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Mafalda Sarraguça is a researcher at LAQV/REQUIMTE/FFUP and an invited professor at the University of Porto's Faculty of Pharmacy (FFUP), where she also earned her PhD in Pharmaceutical Sciences (Analytical Chemistry) in 2010. She previously graduated from the University of Coimbra with a degree in Industrial Chemistry (2000) and a Master’s in Chemistry (Chemical Control, 2004). Her research focuses on supramolecular chemistry to enhance drug properties like solubility, palatability, and mechanical properties. She also works on optimizing the extraction of bioactive compounds with pharmaceutical interest using green chemistry approaches. Proficient in several solid-state analytical methods (mid- and near-infrared spectroscopy, Raman spectroscopy, and differential scanning calorimetry), she also applied multivariate analysis to improve pharmaceutical industrial processes. Dr. Sarraguça has co-authored 46 peer-reviewed publications in international journals (over 1300 citations, h-index of 19), including 11 as corresponding author, and 4 invited book chapters. She has supervised and co-supervised several PhD student, master's and research training students. She has delivered 40 oral communications at national and international conferences (5 invited) and 6 invited webinars and presented over 55 posters. Dr. Sarraguça has participated in 8 scientific projects (4 national, 4 international, including 1 European), serving as a PI in the FECT 2024 projects (ESCAPE-TB) and a co-PI of the FCT project "Honey2KILL." She was active in COST Action CA18112 (Mechanochemistry for Sustainable Industry) as Gender Balance co-leader and a member of the communication team. She led WG4in COST Action CA18224 (Green Chemical Engineering Network towards upscaling sustainable processes) and is a member of COST Actions CA21164 (Towards an improvement in diagnostics and treatment strategies for TB control) and CA22107 (Bringing Experiment and Simulation Together in Crystal Structure Prediction).
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Identification

Personal identification

Full name
Mafalda Sofia Coelho da Cruz Sarraguça

Citation names

  • Sarraguça, Mafalda
  • Sarraguça Cruz Mafalda
  • Cruz Mafalda
  • Sarraguça C. Mafalda

Author identifiers

Ciência ID
4710-B5E5-5036
ORCID iD
0000-0003-0294-5596
Researcher Id
A-4700-2009
Scopus Author Id
24765266100

Email addresses

  • mafalda.cruz@ff.up.pt (Professional)

Telephones

Fax
  • 226093483 (Professional)
Telephone
  • 220428662 (Professional)

Addresses

  • LAQV/REQUIMTE, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto. Rua Jorge de Viterbo, nº 228, 4050-313 , Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Exact Sciences - Chemical Sciences

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1) Elementary (A2)
Portuguese (Mother tongue)
Education
Degree Classification
2011/04/01 - 2017/07/31
Concluded
 Post-Doctoral (Pós-doutoramento)
Major in Pharmaceutical Sciences
REQUIMTE LAQV Porto, Portugal
2006/10/01 - 2010/12/06
Concluded
 PhD in Pharmaceutical Sciences (Doutoramento)
Major in Pharmaceutical Sciences - Analytical Chemistry
Universidade do Porto Faculdade de Farmácia, Portugal
"Improved quality control of solid dosage forms for the pharmaceutical industry with high-throughput vibrational spectroscopy" (THESIS/DISSERTATION)
 Approved with distinction
2002/09/01 - 2004/06/21
Concluded
 Master in Chemistry - Quality Control (Mestrado)
Major in Chemical Sciences
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
" Solid state chemistry of betaxolol hydrochloride" (THESIS/DISSERTATION)
 Very Good
1995/09/01 - 2000/06/29
Concluded
 Graduation in Industrial Chemistry (Licenciatura)
Major in Chemical Sciences
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Enthalpy of vaporization of butanediols " (THESIS/DISSERTATION)
 13 valores
Affiliation

Science

Category
Host institution 		Employer
2023/08/01 - Current Auxiliary Researcher (Research) REQUIMTE LAQV Porto, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal
2017/08/01 - 2023/07/31 Researcher (Research) Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
REQUIMTE LAQV Porto, Portugal
2015/10/30 - 2015/11/07 Visiting Researcher (Research) REQUIMTE LAQV Porto, Portugal
Universidade Federal do Maranhão, Brazil
2010/04/01 - 2010/06/30 Visiting Researcher (Research) Universitat Autònoma de Barcelona, Spain
2009/05/01 - 2009/07/03 Visiting Researcher (Research) Universiteit Gent, Belgium
2001/01/01 - 2002/12/31 Research Trainee (Research) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2000/10/01 - 2000/12/15 Visiting Researcher (Research) Lunds Universitet, Sweden

Teaching in Higher Education

Category
Host institution 		Employer
2021/09/01 - Current Invited Assistant Professor (University Teacher) Universidade do Porto Faculdade de Farmácia, Portugal
Universidade do Porto Faculdade de Farmácia, Portugal

Other Careers

Category
Host institution 		Employer
2010/09/01 - 2010/12/31 Carreiras / Categorias Subsistentes WorldMetrics, Portugal
2005/01/14 - 2005/03/23 Professor do ensino básico e secundário (Professor do ensino básico e secundário) Escola Secundária, Dr. António Granjo , Portugal
2004/02/01 - 2004/08/31 Professor do ensino básico e secundário (Professor do ensino básico e secundário) Escola Secundára da Anadia, Portugal
2003/04/01 - 2003/08/31 Professor do ensino básico e secundário (Professor do ensino básico e secundário) Escola E.B. 2 3 Jorge de Montemor, Portugal

Others

Category
Host institution 		Employer
2005/04/03 - 2005/10/31 Internship Celbi SA, Portugal
2004/07/16 - 2005/01/15 Internship Soporcel , Portugal
Projects

Grant

Designation Funders
2011/04/01 - 2017/07/31 HIGH-THROUGHPUT SPECTROSCOPIC CHARACTERIZATION OF SOLID FORMS AND COCRYSTALS: IMPROVING PHARMACEUTICAL MANUFACTURING AND ENHANCING PHARMACOLOGICAL PROPERTIES
SFRH/BPD/74788/2010
Post-doc
Fundação para a Ciência e a Tecnologia
Concluded
2006/10/01 - 2010/09/30 MONITORIZAÇÃO AVANÇADA DE ESPECIALIDADES FARMACÊUTICAS POR ESPECTROSCOPIA DE INFRA-VERMELHO PRÓXIMO NIR E RAMAN COM MÉTODOS QUIMIOMÉTRICOS
SFRH/BD/32614/2006
PhD Student Fellow
Universidade do Porto Faculdade de Ciências, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2001/01/01 - 2003/12/31 A Thermodynamic and Spectroscopic Approach to the Study of Intermolecular Interactions in Hydroxylated Organic Compounds
PRAXIS/QUI/10137/98
Scientific Initiation Fellow
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2023/08/01 - 2029/07/31 A new perspective on the treatment of tuberculosis in children by giving a new life to existent drugs - CEECIND
2022.01388.CEECIND
10.54499/2022.01388.CEECIND/CP1724/CT0003
10.54499/2022.01388.CEECIND/CP1724/CT0003
Principal investigator
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Ongoing
2019/01/01 - 2019/12/31 LAQV (Associated Laboratory for Green Chemistry - Clean Technologies and Processes)
UID/QUI/50006/2019
LA/P/0008/2020
10.54499/LA/P/0008/2020
Universidade do Porto Faculdade de Ciências, Portugal

Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade Nova de Lisboa, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade de Aveiro, Portugal

Universidade de Évora, Portugal

Unidade de Investigação Vidro e Cerâmica para as Artes, Portugal

Universidade de Lisboa Instituto Dom Luiz, Portugal

Universidade Nova de Lisboa Associação para a Inovação e Desenvolvimento da FCT, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2010/01/22 - 2013/01/21 Beleza e significado da cor na iluminura medieval portuguesa[Colour in medieval illuminated manuscripts :between beauty and meaning]
PTDC/EAT-EAT/104930/2008
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal

Universidade Nova de Lisboa Laboratório para a Ciência da Computação e Informática, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade Nova de Lisboa Faculdade de Ciências Sociais e Humanas, Portugal

Instituto de Biologia Experimental e Tecnológica, Portugal

Universidade de Lisboa Instituto Dom Luiz, Portugal

Universidade Nova de Lisboa Instituto de Estudos Medievais, Portugal
Fundação para a Ciência e a Tecnologia
Concluded

Other

Designation Funders
2023/02/01 - Current Towards an improvement in diagnostics and treatment strategies for TB control - COST Action CA21164
CA21164
Member
European Cooperation in Science and Technology, Belgium
Ongoing
2020/01 - Current Green Chemical Engineering Network towards upscaling sustainable processes
CA18224
Member
European Cooperation in Science and Technology, Belgium
Ongoing
2025/07/01 - 2028/06/29 ESCAPE_TB - Eutectic Solutions for Controlled and Advanced Pulmonary Enhancement in Tuberculosis
COMPETE2030-FEDER-00662700
15566
Principal investigator
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia

Fundo Europeu de Desenvolvimento Regional.
Ongoing
2023/10/02 - 2027/09/17 Bringing Experiment and Simulation Together in Crystal Structure Prediction- CA22107
CA22107
Other
European Cooperation in Science and Technology, Belgium
Ongoing
2022/10/01 - 2026/09/30 Innovative Mechanochemical Processes to synthesize green ACTIVE pharmaceutical ingredients
101057286
10.3030/101057286
Researcher
Universidade de Lisboa Centro de Química Estrutural, Portugal
 European Union
Ongoing
2020/01/01 - 2023/12/31 Associated Laboratory for Green Chemistry - Clean Technologies and Processes
UIDP/50006/2020
Researcher
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/02/27 - 2023/08/26 MechanoChemistry for Sustainable Industry - COST Action CA18112
CA18112
Member
European Cooperation in Science and Technology, Belgium
Concluded
2022/01/01 - 2023/06/30 Honey2KILL- Honey-exosomes to fight superbugs
EXPL/NAN-MAT/0743/2021
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2020/11/06 - 2022/11/06 Development and characterization of new solid dispersions of drugs used in the treatment of tuberculosis
UNIVERSAL-00998/19
Researcher
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal

Universidade Estadual da Região Tocantina do Maranhão, Brazil
Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão
Concluded
2016/11/14 - 2018/11/14 HANSENÍASE - synthesis and characterization of co-crystals of drugs used in the treatment of leprosy
05974/16
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão
Concluded
2014/05/13 - 2017/05/16 NOFARMA: Synthesis and spectroscopic characterization of co-crystals and polymorphic forms of drugs widely used by the Brazilian population
00284-14
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão
Concluded
2012/02/01 - 2015/02/01 BIOTEXTILE - Sequencing batch reactor biotechnology toward effective textile wastewater treatment
Provided by PTCRIS: 120624
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2010/01/22 - 2012/01/22 Colour in medieval illuminated manuscripts: between beauty and meaning
Provided by PTCRIS: 104930
Researcher
Universidade do Porto Faculdade de Farmácia, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
Outputs

Publications

Book chapter
  1. Passos, Marieta L.C.; Sarraguça, Mafalda C.; Saraiva, M. Lúcia M.F.S.; Prasada Rao, T.; Biju, V.M.. "Organic Compounds". In Encyclopedia of Analytical Science, 236-243. Elsevier, 2019.
    Published • 10.1016/b978-0-12-409547-2.14465-8
  2. Lopes, João A.; Sarraguça, Mafalda C.. "Data Processing in Multivariate Analysis of Pharmaceutical Processes". In Multivariate Analysis in the Pharmaceutical Industry, 35-51. Elsevier, 2018.
    Published • 10.1016/b978-0-12-811065-2.00002-3
  3. Mafalda C. Sarraguca; Ricardo Pascoa; Miguel Lopo; Jorge Sarraguca; Joao A. Lopes. "Bioactive Compounds in Coffee as Health Promotors". In Natural Bioactive Compounds from Fruits and Vegetables as Health Promoters Part II, 180-220. BENTHAM SCIENCE PUBLISHERS, 2016.
    Published • 10.2174/9781681082431116010011
  4. Páscoa, R.N.M.J.; Sarraguça, M.C.; Magalhães, L.M.; Santos, J.R.; Rangel, A.O.S.S.; Lopes, J.A.. "Use of Near-Infrared Spectroscopy for Coffee Beans Quality Assessment". In Disease Prevention and Health Promotion, 933-941. Academic Press, 2015.
    Published • 10.1016/B978-0-12-409517-5.00103-0
Conference abstract
  1. Marisa Freitas; Carina Proença; Sarraguça C. Mafalda; Daniela Ribeiro; Eduarda Fernandes. "Assessment of HOCl Production in Human blood: Experimental Optimization and Proof of Concept for the Antioxidant Activity of Flavonoids in this Complex Matrix". Paper presented in 27th Annual Conference of the Society for Redox Biology and Medicine, 2020.
    Published
  2. Daniela Ribeiro ; Tânia Soares; Sílvia Rocha; Sarraguça, Mafalda; Eduarda Fernandes; Marisa Freitas. "Optimization of experimental settings for the assessment of HOCl in human blood, using the fluorescent probe APF". Paper presented in 19th Biennial Meeting for the Society for Free Radical Research International (SFRRI), Lisboa, 2018.
    Published
Conference poster
  1. Sarraguça Cruz Mafalda. Corresponding author: Sarraguça Cruz Mafalda. "Green Mechanochemical Synthesis of a Novel Drug-Drug Eutectic Mixture of Acetylsalicylic Acid and Pyrazinamide for Enhanced Drug Delivery". Paper presented in INCOME, 2025.
  2. Sarraguça C. Mafalda. "ESCAPE-TB - Eutectic Solutions for Controlled and Advanced Pulmonary Enhancement in Tuberculosis". Paper presented in Advance TB GP3 annual meeting - Current topics in TB and pulmonary mycobacteriosis: from immunity to diagnostic approach, 2025.
  3. Sevin Uner; Nunes, Cláudia; Sarraguça C. Mafalda. Corresponding author: Sarraguça C. Mafalda. "Nano delivery of isoniazid-based therapeutic deep eutectic systems for enhanced tuberculosis treatment". Paper presented in InnovDelivery'25 - II Lusophone Meeting on Innovative Delivery Systems, 2025.
  4. Myriam Taghouti; Sarraguça C. Mafalda; Azza Silotri-Naik; Atif Emre Demet. "Shaping sustainable agri-food chains: identifying future skills and actions to enhance upcycled ingredients uptake". Paper presented in 13º Jornadas de Alimentação Animal, 2024.
  5. Sarraguça C. Mafalda. "Multivariate Analysis for Cocrystal Property Prediction: A promising approach?". Paper presented in From Molecules to Materials: 1st Workshop on Benchmarking Solid State Properties, 2024.
  6. Sarraguça Cruz Mafalda. "IMPACTIVE: Mechanochemistry for greener pharma". Paper presented in CQE days, 2024.
  7. Catia Ferreira; Manuela Moreira; Sarraguça C. Mafalda. Corresponding author: Catia Ferreira. "EXTRACTION OF BIOACTIVE COMPOUNDS FROM GRAPE POMACE USING DEEP EUTECTIC SOLVENTS". Paper presented in 8 PYCheM, 2023.
  8. Catarina Carvalho; Sarraguça C. Mafalda; Reis, Salette. Corresponding author: Catarina Carvalho. "Development of green solvents for the pharmaceutical industry". Paper presented in IJUP 23- Tenth Meeting of Young Researcher of University of Porto, 2023.
  9. Sarraguça C. Mafalda; Tânia Moniz; Vinhas, Sílvia; Reis, Salette; Maia Rangel. Corresponding author: Sarraguça C. Mafalda. "A sustainable strategy for the withdrawal of cellulose from eucalyptus tree wood waste using deep eutectic solvents and microwave-assisted extraction". Paper presented in 2nd Greenering International Conference, 2023.
  10. Tânia Moniz; Vinhas, Sílvia; Sarraguça C. Mafalda; Reis, Salette; Rangel, Maria. Corresponding author: Tânia Moniz. "A microwave-assisted approach for cellulose extraction from Eucalyptus and Pine tree wood by-products". Paper presented in XXVI ENCONTRO GALEGO-PORTUGUÉS DE QUÍMICA, 2022.
  11. Sarraguça C. Mafalda; Sousa, Marcus Lima; Adenilson Santos; Jorge Sarraguça; João Almeida Lopes; da Silva Ribeiro, Paulo Roberto. Corresponding author: Sarraguça C. Mafalda. "Multicomponent forms of Clofazimine by mechanochemistry". Paper presented in 10th International Conference on Mechanochemistry and Mechanical Alloying, 2022.
  12. Catarina Carvalho; Sarraguça C. Mafalda. Corresponding author: Sarraguça C. Mafalda. "Development of green solvents for the pharmaceutical industry". Paper presented in Encontro de Investigação Jovem Universidade do Porto, 2022.
  13. Marisa Freitas; Carina Proença; Sarraguça C. Mafalda; Daniela Ribeiro; Eduarda Fernandes. "Assessment of HOCl Production in Human blood: Experimental Optimization and Proof of Concept for the Antioxidant Activity of Flavonoids in this Complex Matrix". Paper presented in 27th Annual Conference of the Society for Redox Biology and Medicine, 2020.
  14. André R. T. S. Araujo; Sarraguça, Mafalda; Márcio Rodrigues; Maximiano Prata Ribeiro; Paula Coutinho; Elena Falqué. "Physico-chemical fingerprinting of mineral medicinal waters of Ourense (Galicia)". Paper presented in International Symposium on Thermalism and Quality of Life (STCV-2019), 2019.
  15. Marisa Rodrigues; João Almeida Lopes; João Figueirinhas; Carlos Cruz; Alexandra Guedes; Sarraguça, Mafalda. "High-throughput screening of hydrochlorothiazide cocrystals by vibrational spectroscopy". Paper presented in XXVI Meeting of the National Portuguese Chemical Society, 2019.
  16. Renato Gil; Sarraguça, Mafalda; Célia Amorim; Conceição Montenegro; Alberto Araújo. "Lithium determination in human serum with improved accuracy using potentiometric detection". Paper presented in XXVI Meeting of the National Portuguese Chemical Society, 2019.
  17. Marisa Rodrigues; Joao A. Lopes; Mafalda Sarraguca. Corresponding author: Marisa Rodrigues. "Pharmaceutical cocrystallization techniques. Advances and Chalanges". Paper presented in XXIV Meeting Galitian-Portuguese of Chemistry, 2018.
  18. Ana Silva; Mafalda Sarraguca (presenter); M. Fonteyne; J. Vercruysse; F. De Leersnyder ; V. Vanhoorne; N. Bostijn; et al. "Multivariate statistical process control of a continuous pharmaceutical twin-screw granulation and fluid bed drying process". Paper presented in EuPAT 9 - Nineth pan-European QbD &PAT Science Conference European, 2018.
    10.1016/j.ijpharm.2017.05.075
  19. Lourenço, Dina; Sarraguça, Mafalda; Alves, Gilberto; Coutinho, Paula; Araujo, A.R.T.S.; Rodrigues, Márcio. "HPLC-DAD method for determination of zonisamide in human plasma using microextraction by packed sorbent optimized by Plackett-Burman experimental design". Paper presented in 32nd International Epilepsy Congress, 2017.
  20. Pedro Cruz; João A. Lopes; Mafalda Sarraguca. "Synthesis of co-amorphous drugs by freeze-drying of low solubility drugs". Paper presented in XXV Meeting of the National Portuguese Chemical Society, 2017.
  21. Marisa Rodrigues; Joao A. Lopes; Mafalda Sarraguca. "Cocrystallization screening of new hydrochlorothiazide cocrystals". Paper presented in XXV Meeting of the National Portuguese Chemical Society, 2017.
  22. Silvério Ferreira Silva Filho ; Andreia Cardoso Pereira; Jorge Sarraguca; Mafalda Sarraguca; Joao A. Lopes; Pedro Freitas Filho ; Adenilson Santos; Paulo Roberto S. Ribeiro. "Crystallographic, thermodynamic and spectroscopic characterization of glibenclamide:tromethamine 1:1 cocrystal synthesized by slow evaporation". Paper presented in XXV Meeting of the National Portuguese Chemical Society, 2017.
  23. Tânia Soares; Carina Proênça; Mafalda Sarraguca; Eduarda Fernandes; Marisa Freitas. "Optimization of experimental settings for the analysis of reactive oxygen and nitrogen species production in human blood using DCFH-DA". Paper presented in IJUP 17- Tenth Meeting of Young Researcher of University of Porto, 2017.
  24. Pedro Cruz; Mafalda Sarraguca. "Synthesis and quality control of new drugs with improved solubility: co-amorphization by freeze-drying of low solubility drugs". Paper presented in IJUP 17- Tenth Meeting of Young Researcher of University of Porto, 2017.
  25. Marisa Rodrigues; Mafalda Sarraguca. "Optimization of cocrystallization processes. Cocrystallization by solvent evaporation and microwave assisted". Paper presented in IJUP 17- Tenth Meeting of Young Researcher of University of Porto, 2017.
  26. Bárabra Baptista ; Mafalda Sarraguca (presenter); Joao A. Lopes. "Synthesis, characterization and use in a formulation of glibenclamide and gliclazide cocrystals". Paper presented in EuPAT 8 - Eight pan-European QbD &PAT Science Conference European, 2016.
  27. Mafalda Sarraguca (presenter); Paulo Roberto S. Ribeiro; Adenilson Santos; João A. Lopes. "Monitoring of a cocrystallization process with process analytical technology". Paper presented in XX Meeting Galitian-Portuguese of Chemistry, 2014.
  28. Nídia Lourenço ; Mafalda Sarraguca (presenter); Helena Pinheiro; João A. Lopes. "A process analytical technology approach for the in-situ monitoring of sequencing batch reactors treating dye-laden textile wastewater". Paper presented in XX Meeting Galitian-Portuguese of Chemistry, 2014.
  29. Mafalda Sarraguca (presenter); Paulo Roberto S. Ribeiro; João A. Lopes. "A PAT approach for the on-line monitoring of pharmaceutical co-crystals formation with near infrared spectroscopy". Paper presented in EuroPACT 2014 - 3rd European Conference on Process Analytics and Control Technology, 2014.
  30. Mafalda Sarraguca; Paulo Roberto S. Ribeiro; Rita Matias; Joao A. Lopes. "Quality-by-design applied to dissolution tests: in-situ NIR spectroscopy monitoring". Paper presented in EuPAT 6 - Sixth pan-European QbD &PAT Science Conference European, 2013.
  31. Mafalda Sarraguca (presenter); Paulo Roberto S. Ribeiro; Rita Matias; João A. Lopes. "A new simple and sensitive spectrophotometric method for the determination of folic acid in pharmaceutical formulations". Paper presented in XXIII Meeting of the National Portuguese Chemical Society., 2013.
  32. Raquel Figueiredo; Rita Matias; Mafalda Sarraguca; João A. Lopes. "A PAT/QbD approach for in-situ monitoring of drug dissolution tests with NIR spectroscopy". Paper presented in XVIII Meeting Galitian-Portuguese of Chemistry, 2012.
  33. Raquel Figueiredo; Mafalda Sarraguca; Jorge Salvador; Joao A. Lopes. "NIR diffuse reflectance spectroscopy to assess tablets dissolution profiles". Paper presented in EuPAT 5 - Fifht pan-European QbD &PAT Science Conference European, 2012.
  34. Sarraguça, Mafalda; Mafalda Sarraguca; Jorge Salvador; João A. Lopes. "A new trend for NIR spectroscopy: in-situ monitoring of dissolution tests". Paper presented in EuPAT 5 - Fifht pan-European QbD &PAT Science Conference European, 2012.
  35. João Santos; Mafalda Sarraguca (presenter); João A. Lopes; António O.S.S. Rangel. "Evaluation of green coffee quality using NIR spectroscopy: a quantitative approach". Paper presented in XVII Meeting Galitian-Portuguese of Chemistry, 2011.
  36. Rodrigo Santos; Mafalda Sarraguca; João A. Lopes; António O.S.S. Rangel. "Authenticity assessment of roasted coffee brands using near infrared spectroscopy". Paper presented in XVII Meeting Galitian-Portuguese of Chemistry, 2011.
  37. Mafalda Sarraguca (presenter); Joao A. Lopes. "Improved quality control of solid dosage forms for the pharmaceutical industry with high-throughput near infrared spectroscopy". Paper presented in XXII Meeting of the National Portuguese Chemical Society, 2011.
  38. Sandra Soares; Helena Amara ; Paulo Costa; Mafalda Sarraguca; João A. Lopes. "Near infrared spectroscopy for polymorphism characterization in pharmaceutical solid dosage forms". Paper presented in IJUP 11- Fourth Meeting of Young Researcher of University of Porto, 2011.
  39. Carla P. Coutinho; Mafalda Sarraguca; Jorge Sarraguca; Luís Meirinhos-Soares; Mónica Miranda; Raquel Guiomar; Jorge Machado; et al. "Fourier-transform infrared spectroscopy in bacteriology". Paper presented in REQUIMTE National Meeting, 2011.
  40. Mafalda Sarraguça (presenter); Ana Cruz; Helena Amaral; Paulo Costa; Joao A. Lopes; Mafalda Sarraguca; João A. Lopes. "Particle size determination in pharmaceuticals by near infrared spectroscopy". Paper presented in VII Colloquium Chemiometricum Mediterraneum, 2010.
  41. Mafalda Sarraguca; Cristina Leandro; Joao A. Lopes. "High-throughput pharmaceutical process quality control (PAT): practical implementation and revenue". Paper presented in EuPAT 4 - Fourth pan-European QbD &PAT Science Conference, 2010.
  42. Ana Cruz; Mafalda Sarraguça; Paulo Costa; Helena Amaral; Joao A. Lopes. "Using NIR to a deep understanding of pharmaceutical powders physical properties". Paper presented in IJUP 10 - Third Meeting of Young Researcher of University of Porto, 2010.
  43. Sandra Soares; Mafalda Sarraguca; Paulo Costa; Helena Amaral; João A. Lopes. "NIR for polymorphism characterization and quantifcation in pharmaceutical dosage forms". Paper presented in IJUP 10 - Third Meeting of Young Researcher of University of Porto, 2010.
  44. Mafalda Sarraguca (presenter); João A. Lopes. "A novel method to determine aminoglycosides in pharmaceutical solid formulations". Paper presented in 14th Internatioanal Conference on Near Infrared Spectroscopy, 2009.
  45. Ana Cruz; Sandra Soares; Mafalda Sarraguca; Paulo Costa; Helena Amaral; Joao A. Lopes. "Advanced control of pharmaceutical specialties with near infrared spectroscopy". Paper presented in IJUP 09 - Second Meeting of Young Researcher of University of Porto., 2009.
  46. Sandra Soares; Mafalda Sarraguca; Paulo Costa; Helena Amaral; João A. Lopes. "Analysis of UV degradation of active pharmaceutical ingredients in powder form with near infrared spectroscopy". Paper presented in IJUP09 - Second Meeting of Young Researcher of University of Porto., 2009.
  47. Mafalda Sarraguca; Ana Cruz; Sandra Soares; Paulo Costa; Helena Amaral; Joao A. Lopes. "Determination of physical parameters in pharmaceutical powders by near infrared spectroscopy". Paper presented in 19th International Symposium on Pharmaceutical and Biomedical Analysis, 2008.
  48. Adriano Fachini; Mafalda Sarraguca; Joao A. Lopes. "Unveiling chemical and physical information from chemometrics models". Paper presented in XXI Meeting of the National Portuguese Chemical Society, 2008.
  49. A. Paulo; A. Dias; Mafalda Sarraguca; Joao A. Lopes; M. Alves; E. C. Ferreira. "Surveying an activated sludge reactor using online UV-visible and NIR spectroscopy and chemometrics". Paper presented in SIDISA 08 - Proceedings of the International Symposium on Sanitary and Environmental Engineering, 2008.
  50. Mafalda Sarraguca; João A. Lopes. "The use of net analyte signal (NAS) in NIR Spectroscopy: interpretability and figures of merit". Paper presented in CAC2008 -11th International Conference on Chemometrics in Analytical Chemistry, 2008.
  51. Ana Cruz; Sandra Soares; Mafalda Sarraguca; Paulo Costa; Helena Amaral; Joao A. Lopes. "Determination of physical parameters in pharmaceutical powders by near infrared spectroscopy". Paper presented in IJUP 08 - First Meeting of Young Researcher of University of Porto, 2008.
  52. Mafalda Sarraguca (presenter); Joao A. Lopes. "Quality control of pharmaceuticals with NIR: from lab to process line". Paper presented in 13th Internatioanal Conference on Near Infrared Spectroscopy, 2007.
  53. João Canotilho; Mafalda Cruz; Maria Luísa Planas Leitão ; Adriano Sousa; J. Redinha. "Thermospectroscopic studies in the stretching region of betaxolol and betaxolol hydrochloride". Paper presented in 7th International Conference/Workshop on Pharmacy and Applied Physical Chemistry, 2003.
  54. Mafalda Cruz (presenter); João Canotilho; Maria Luísa Planas Leitão. "Structural modifications in betaxolol hydrochloride on heating/cooling cycles". Paper presented in 6th Mediterranean Conference on Calorimetry and Thermal Analysis, 2003.
  55. Maria Luísa Planas Leitão ; Mafalda Cruz; João Canotilho. "Thermal behaviour of betaxolol". Paper presented in 8th European Symposium on Thermal Analysis and Calorimetry, 2002.
  56. Paula Barreleiro; Mafalda Cruz; S. Ferreira; G. Olofsson. "Factors influencing the energetics of DNA-cationic vesicle formation". Paper presented in XV Conference of the European Colloid & Interface Society - ECIS, 2001.
  57. Ermelinda Eusébio ; Lopes Jesus, A.J.; M.T.S. Rosado; Mafalda Cruz; Maria Luísa Planas Leitão ; Redinha, J.S.. "Butanediols: enthalpies of vaporization and gas state molecular structure". Paper presented in 12th International Congress on Thermal Analysis and Calorimetry, 2000.
Encyclopedia entry
  1. André, Vânia; Duarte, M. Teresa; Clara S. B. Gomes; Mafalda Sarrguça. Corresponding author: Mafalda Sarrguça. "Mechanochemistry in Portugal". In Encyclopedia: Where Brilliant Minds Gather. MDPI, 2022. https://encyclopedia.pub/19902.
    Published
Journal article
  1. Simão Pinho; Carla Santos; Tânia Moniz; Andreia Granja; Mafalda Sarraguça; Salette Reis; Maria Rangel; Marta Vasconcelos. Corresponding author: Marta Vasconcelos. "Novel polymeric nanoparticles as nanofertilisers for alkaline iron-deficient conditions". Plant and Soil (2025): http://dx.doi.org/10.1007/s11104-025-07462-y.
    Open access • Published • 10.1007/s11104-025-07462-y
  2. Luís H. S. Queiroz; Mateus R. Lage; Clenilton C. dos Santos; Mafalda C. Sarraguça; Paulo R. S. Ribeiro. "Thermodynamic and Structural Characterization of a Mechanochemically Synthesized Pyrazinamide–Acetylsalicylic–Acid Eutectic Mixture". Pharmaceuticals (2025): https://doi.org/10.3390/ph18020211.
    Open access • Published • 10.3390/ph18020211
  3. Queiroz, Luís H. S.; Barros, Ranna S.; de Sousa, Francisco F.; Lage, Mateus R.; Sarraguça, Mafalda C.; Ribeiro, Paulo R. S.. "Preparation and Characterization of a Rifampicin Coamorphous Material with Tromethamine Coformer: An Experimental–Theoretical Study". Molecular Pharmaceutics 21 3 (2024): 1272-1284. http://dx.doi.org/10.1021/acs.molpharmaceut.3c00947.
    Published • 10.1021/acs.molpharmaceut.3c00947
  4. Cátia Ferreira; Mafalda Sarraguça. Corresponding author: Mafalda Sarraguça. "A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest". Pharmaceuticals 17 124 (2024): https://doi.org/10.3390/ph17010124.
    Open access • Published • 10.3390/ph17010124
  5. Vinhas, Silvia; Sarraguça C. Mafalda; Moniz, Tânia; Reis, Salette; Rangel, Maria. Corresponding author: Moniz, Tânia. "A New Microwave-Assisted Protocol for Cellulose Extraction from Eucalyptus and Pine Tree Wood Waste". Polymers 16 1 (2023): 20. http://dx.doi.org/10.3390/polym16010020.
    Open access • Published • 10.3390/polym16010020
  6. Cátia Ferreira; Manuela M. Moreira; Cristina Delerue-Matos; Mafalda Sarraguça. Corresponding author: Mafalda Sarraguça. "Subcritical Water Extraction to Valorize Grape Biomass- A Step Closer to Circular Economy". Molecules 28 22 (2023): 7538. https://doi.org/10.3390/molecules28227538.
    Open access • Published • 10.3390/molecules28227538
  7. Joana Gonçalves; Cláudia Marques; Cláudia Nunes; Mafalda Sarraguça. Corresponding author: Mafalda Sarraguça. "Therapeutic Liquid Eutectic Solvents in Lipid Nanoparticles as Drug Vehicles - A Proof of Concept". International Journal of Molecular Sciences 24 21 (2023): 15648. https://doi.org/10.3390/ijms242115648.
    Published • 10.3390/ijms242115648
  8. Passos, Marieta L.C.; Wicinska, Aleksandra; Sarraguça, Mafalda; Saraiva, M. Lúcia M.F.S.. "An automatic approach for the evaluation of the effect of ionic liquids and deep eutectic solvents on elastase". Journal of Molecular Liquids 373 (2023): 121240. http://dx.doi.org/10.1016/j.molliq.2023.121240.
    10.1016/j.molliq.2023.121240
  9. R. Sá, Mônica; Sarraguça, Jorge M.G.; de Sousa, Francisco F.; Sarraguça, Mafalda S.C.; Lopes, João A.; Lima, Antonio Douglas da S.G.; Lage, Mateus R.; Ribeiro, Paulo R.S.. "Structural, thermal, vibrational, solubility and DFT studies of a tolbutamide co-amorphous drug delivery system for treatment of diabetes". International Journal of Pharmaceutics 615 (2022): 121500. http://dx.doi.org/10.1016/j.ijpharm.2022.121500.
    10.1016/j.ijpharm.2022.121500
  10. Sarraguça, Mafalda C.; Ribeiro, Paulo R. S.; Nunes, Cláudia; Seabra, Catarina Leal. Corresponding author: Sarraguça, Mafalda C.. "Solids Turn into Liquids-Liquid Eutectic Systems of Pharmaceutics to Improve Drug Solubility". Pharmaceuticals 15 3 (2022): 279. http://dx.doi.org/10.3390/ph15030279.
    Open access • Published • 10.3390/ph15030279
  11. Teresa Paiva; Telma A. Jacinto; Sarraguça C. Mafalda; Paula Coutinho. Corresponding author: Teresa Paiva. "Beef Consumers Behaviour and Preferences - The Case of Portugal". Sustainability 14 2358 (2022): 1-21. https://www.mdpi.com/2071-1050/14/4/2358.
    Open access • Published
  12. André, Vânia; Duarte, M. Teresa; Gomes, Clara S. B.; Sarraguça, Mafalda C.. Corresponding author: Sarraguça, Mafalda C.. "Mechanochemistry in Portugal: A Step towards Sustainable Chemical Synthesis". Molecules 27 1 (2021): 241. http://dx.doi.org/10.3390/molecules27010241.
    Open access • Published • 10.3390/molecules27010241
  13. Queiroz, Ana Luiza P.; Rodrigues, Marisa; Zeglinski, Jacek; Crean, Abina M.; Sarraguça, Mafalda Cruz ; Vucen, Sonja. Corresponding author: Sarraguça, Mafalda Cruz. "Determination of co-crystal phase purity by mid infrared spectroscopy and multiple curve resolution". International Journal of Pharmaceutics 595 (2021): 120246. http://dx.doi.org/10.1016/j.ijpharm.2021.120246.
    Published
  14. Moreira, Miguel; Cruz Sarraguça, Mafalda. Corresponding author: Cruz Sarraguça, Mafalda. "How can oral paediatric formulations be improved? A challenge for the XXI century". International Journal of Pharmaceutics 590 (2020): 119905. http://dx.doi.org/10.1016/j.ijpharm.2020.119905.
    Published • 10.1016/j.ijpharm.2020.119905
  15. Sousa, Marcus Lima; Sarraguça, Mafalda C.; Oliveira dos Santos, Adenilson; Sarraguça, Jorge M.G.; Lopes, João; S Ribeiro, Paulo Roberto. "A new salt of clofazimine to improve leprosy treatment". Journal of Molecular Structure 1214 (2020): 128226. http://dx.doi.org/10.1016/j.molstruc.2020.128226.
    Published • 10.1016/j.molstruc.2020.128226
  16. Rodrigues, Marisa; Lopes, João; Guedes, Alexandra; Sarraguça, Jorge; Sarraguca, Mafalda Cruz. Corresponding author: Sarraguca, Mafalda Cruz. "Considerations on high-throughput cocrystals screening by ultrasound assisted cocrystallization and vibrational spectroscopy". Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 229 (2020): 117876. http://dx.doi.org/10.1016/j.saa.2019.117876.
    Published • 10.1016/j.saa.2019.117876
  17. Soares, Tânia; Rodrigues, Daniela; Sarraguça, Mafalda; Rocha, Sílvia; Lima, José L. F. C.; Ribeiro, Daniela; Fernandes, Eduarda; Freitas, Marisa. "Optimization of Experimental Settings for the Assessment of Reactive Oxygen Species Production by Human Blood". Oxidative Medicine and Cellular Longevity 2019 (2019): 1-11. http://dx.doi.org/10.1155/2019/7198484.
    Open access • Published • 10.1155/2019/7198484
  18. Silva, A.F.; Vercruysse, J.; Vervaet, C.; Remon, J.P.; Lopes, J.A.; De Beer, T.; Sarraguça, M.C.. "In-Depth Evaluation of Data Collected During a Continuous Pharmaceutical Manufacturing Process: A Multivariate Statistical Process Monitoring Approach". Journal of Pharmaceutical Sciences 108 1 (2019): 439-450. https://www.sciencedirect.com/science/article/pii/S0022354918305112.
    Published • 10.1016/j.xphs.2018.07.033
  19. Marisa Rodrigues; João Lopes; Cruz Sarraguça, Mafalda. Corresponding author: Cruz Sarraguça, Mafalda. "Vibrational Spectroscopy for Cocrystals Screening. A Comparative Study". Molecules 23 3263; (2018): 1-15. https://doi.org/10.3390/molecules23123263.
    Open access • Published • 10.3390/molecules23123263
  20. Silva Filho, Silverio Ferreira; Pereira, Andreia Cardoso; Sarraguça, Jorge M. G.; Sarraguça, Mafalda C.; Lopes, Joao; Facanha Filho, Pedro de Freitas; dos Santos, Adenilson Oliveira; da Silva Ribeiro, Paulo Roberto. "Synthesis of a Glibenclamide Cocrystal: Full Spectroscopic and Thermal Characterization". Journal of Pharmaceutical Sciences 107 6 (2018): 1597-1604. https://www.sciencedirect.com/science/article/pii/S0022354918300789.
    Published • 10.1016/j.xphs.2018.01.029
  21. Silva, A. F.; Vercruysse, J.; Vervaet, C.; Remon, J. P.; Lopes, J. A.; De Beer, T.; Sarraguça, M. C.. "Process monitoring and evaluation of a continuous pharmaceutical twin-screw granulation and drying process using multivariate data analysis". European Journal of Pharmaceutics and Biopharmaceutics 128 (2018): 36-47. https://www.sciencedirect.com/science/article/pii/S0939641117312869.
    Published • 10.1016/j.ejpb.2018.04.011
  22. Rodrigues, Marisa; Baptista, Barbara; Lopes, Joao Almeida; Sarraguça, Mafalda Cruz . Corresponding author: Sarraguça, Mafalda Cruz. "Pharmaceutical cocrystallization techniques. Advances and challenges". International Journal of Pharmaceutics 547 1-2 (2018): 404-420. https://www.sciencedirect.com/science/article/pii/S0378517318304216.
    Published • 10.1016/j.ijpharm.2018.06.024
  23. Cláudia A. Teixeira dos Santos; Ricardo N.M.J. Páscoa; Mafalda Cruz Sarraguça; Patrícia A.L.S. Porto; António L. Cerdeira; J.M. González-Sáiz; C. Pizarro; João A. Lopes. "Merging vibrational spectroscopic data for wine classification according to the geographic origin". Food Research International 102 (2017): 504-510. https://doi.org/10.1016/j.foodres.2017.09.018.
    Published • 10.1016/j.foodres.2017.09.018
  24. Lourenço, Dina; Sarraguça, Mafalda; Alves, Gilberto; Coutinho, Paula; Araujo, André R. T. S.; Rodrigues, Márcio. "A novel HPLC method for the determination of zonisamide in human plasma using microextraction by packed sorbent optimised by experimental design". Anal. Methods 9 40 (2017): 5910-5919. http://dx.doi.org/10.1039/c7ay01912b.
    Published • 10.1039/c7ay01912b
  25. Silva, A.F.T.; Sarraguça, M.C.; Ribeiro, P.R.; Santos, A.O.; De Beer, T.; Lopes, J.A.. "Statistical process control of cocrystallization processes: A comparison between OPLS and PLS". International Journal of Pharmaceutics 520 1-2 (2017): 29-38. https://www.sciencedirect.com/science/article/pii/S0378517317300613.
    Published • 10.1016/j.ijpharm.2017.01.052
  26. A. R. T. S. Araujo; Sarraguça, Mafalda; M. P. Ribeiro; P. Coutinho. "Physicochemical fingerprinting of thermal waters of Beira Interior region of Portugal". Environmental Geochemistry and Health 39 3 (2017): 483-496. http://dx.doi.org/10.1007/s10653-016-9829-x.
    Published • 10.1007/s10653-016-9829-x
  27. Silva, A.F.; Sarraguça, M.C.; Fonteyne, M.; Vercruysse, J.; De Leersnyder, F.; Vanhoorne, V.; Bostijn, N.; et al. Corresponding author: Sarraguça, M.C.. "Multivariate statistical process control of a continuous pharmaceutical twin-screw granulation and fluid bed drying process". International Journal of Pharmaceutics 528 1-2 (2017): 242-252. https://www.sciencedirect.com/science/article/pii/S0378517317304994.
    Published • 10.1016/j.ijpharm.2017.05.075
  28. Mafalda Cruz Sarraguça; Rita Matias; Raquel Figueiredo; Paulo Roberto S. Ribeiro; Ana Teixeira Martins; João Almeida Lopes. "Near infrared spectroscopy to monitor drug release in-situ during dissolution tests". International Journal of Pharmaceutics 513 1-2 (2016): 1-7. https://doi.org/10.1016%2Fj.ijpharm.2016.09.010.
    Published • 10.1016/j.ijpharm.2016.09.010
  29. Sarraguça, M.C.; Paisana, M.; Pinto, J.; Lopes, J.A.. "Real-time monitoring of cocrystallization processes by solvent evaporation: A near infrared study". European Journal of Pharmaceutical Sciences 90 (2016): 76-84. https://www.sciencedirect.com/science/article/pii/S0928098715300981.
    Published • 10.1016/j.ejps.2015.12.025
  30. Cruz, M.V.; Sarraguça, M.C.; Freitas, F.; Lopes, J.A.; Reis, M.A.M.. "Online monitoring of P(3HB) produced from used cooking oil with near-infrared spectroscopy". Journal of Biotechnology 194 (2015): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84919897626&partnerID=MN8TOARS.
    Published • 10.1016/j.jbiotec.2014.11.022
  31. Sarraguça, M.C.; Ribeiro, P.R.S.; Santos, A.O.D.; Lopes, J.A.. "Batch Statistical Process Monitoring Approach to a Cocrystallization Process". Journal of Pharmaceutical Sciences 104 12 (2015): 4099-4108. https://www.sciencedirect.com/science/article/pii/S0022354915000489.
    Published • 10.1002/jps.24623
  32. Matias, R.; Ribeiro, P.R.S.; Sarraguça, M.C.; Lopes, J.A.. "A UV spectrophotometric method for the determination of folic acid in pharmaceutical tablets and dissolution tests". Analytical Methods 6 9 (2014): 3065-3071. https://pubs.rsc.org/en/content/articlelanding/2014/ay/c3ay41874j#!divAbstract.
    Published • 10.1039/c3ay41874j
  33. Sarraguça, M.C.; Ribeiro, P.R.S.; Santos, A.O.; Silva, M.C.D.; Lopes, J.A.. "A PAT approach for the on-line monitoring of pharmaceutical co-crystals formation with near infrared spectroscopy". International Journal of Pharmaceutics 471 1-2 (2014): 478-484. https://www.sciencedirect.com/science/article/pii/S0378517314004232.
    Published • 10.1016/j.ijpharm.2014.06.003
  34. Sarraguça, M.C.; Santos, J.R.; Rangel, A.O.S.S.; Lopes, J.A.. "Authenticity Control of Roasted Coffee Brands Using Near-Infrared Spectroscopy". Food Analytical Methods 6 3 (2013): 892-899. https://link.springer.com/article/10.1007%2Fs12161-012-9499-y.
    Published • 10.1007/s12161-012-9499-y
  35. Santos, J.R.; Sarraguça, M.C.; Rangel, A.O.S.S.; Lopes, J.A.. "Evaluation of green coffee beans quality using near infrared spectroscopy: A quantitative approach". Food Chemistry 135 3 (2012): 1828-1835. https://www.sciencedirect.com/science/article/pii/S0308814612010321.
    10.1016/j.foodchem.2012.06.059
  36. Lourenço, N.D.; Lopes, J.A.; Almeida, C.F.; Sarraguça, M.C.; Pinheiro, H.M.. "Bioreactor monitoring with spectroscopy and chemometrics: A review". Analytical and Bioanalytical Chemistry 404 4 (2012): 1211-1237. https://link.springer.com/article/10.1007%2Fs00216-012-6073-9.
    Published • 10.1007/s00216-012-6073-9
  37. Sarraguça, M.C.; Cruz, A.V.; Amaral, H.R.; Costa, P.C.; Lopes, J.A.. "Comparison of different chemometric and analytical methods for the prediction of particle size distribution in pharmaceutical powders". Analytical and Bioanalytical Chemistry 399 6 (2011): 2137-2147. https://link.springer.com/article/10.1007%2Fs00216-010-4230-6.
    Published • 10.1007/s00216-010-4230-6
  38. Sarraguça, M.C.; Soares, S.O.; Lopes, J.A.. "A near-infrared spectroscopy method to determine aminoglycosides in pharmaceutical formulations". Vibrational Spectroscopy 56 2 (2011): 184-192. https://www.sciencedirect.com/science/article/pii/S0924203111000257.
    Published • 10.1016/j.vibspec.2011.02.007
  39. Canotilho, J.; Castro, R.A.E.; Rosado, M.T.S.; Nunes, S.C.C.; Cruz, M.S.C.; Redinha, J.S.. "Thermal analysis and crystallization from melts: ß-adrenergic compounds". Journal of Thermal Analysis and Calorimetry 100 2 (2010): 423-429. https://link.springer.com/article/10.1007/s10973-009-0645-8.
    Published • 10.1007/s10973-009-0645-8
  40. Sarraguça, M.C.; Cruz, A.V.; Soares, S.O.; Amaral, H.R.; Costa, P.C.; Lopes, J.A.. "Determination of flow properties of pharmaceutical powders by near infrared spectroscopy". Journal of Pharmaceutical and Biomedical Analysis 52 4 (2010): 484-492. https://www.sciencedirect.com/science/article/pii/S0731708510000592.
    Published • 10.1016/j.jpba.2010.01.038
  41. Sarraguça, M.C.; De Beer, T.; Vervaet, C.; Remon, J.-P.; Lopes, J.A.. "A batch modelling approach to monitor a freeze-drying process using in-line Raman spectroscopy". Talanta 83 1 (2010): 130-138. https://www.sciencedirect.com/science/article/pii/S0039914010006909.
    Published • 10.1016/j.talanta.2010.08.051
  42. Sarraguça, M.C.; Lopes, J.A.. "The use of net analyte signal (NAS) in near infrared spectroscopy pharmaceutical applications: Interpretability and figures of merit". Analytica Chimica Acta 642 1-2 (2009): 179-185. https://www.sciencedirect.com/science/article/pii/S0003267008017558.
    Published • 10.1016/j.aca.2008.10.006
  43. Sarraguça, M.C.; Paulo, A.; Alves, M.M.; Dias, A.M.A.; Lopes, J.A.; Ferreira, E.C.. "Quantitative monitoring of an activated sludge reactor using on-line UV-visible and near-infrared spectroscopy". Analytical and Bioanalytical Chemistry 395 4 (2009): 1159-1166. https://link.springer.com/article/10.1007%2Fs00216-009-3042-z.
    Published • 10.1007/s00216-009-3042-z
  44. Sarraguça, M.C.; Lopes, J.A.. "Quality control of pharmaceuticals with NIR: From lab to process line". Vibrational Spectroscopy 49 2 (2009): 204-210. https://www.sciencedirect.com/science/article/pii/S0924203108001239.
    Published • 10.1016/j.vibspec.2008.07.013
  45. Eusébio, M.E.; Lopes Jesus, A.J.; Cruz, M.S.C.; Leitão, M.L.P.; Redinha, J.S.. "Enthalpy of vaporisation of butanediol isomers". Journal of Chemical Thermodynamics 35 1 (2003): 123-129. https://www.sciencedirect.com/science/article/pii/S0021961402003063.
    Published • 10.1016/S0021-9614(02)00306-3
  46. Leitao, M.L.P.; Canotilho, J.; Cruz, M.S.C.; Pereira, J.C.; Sousa, A.T.; Redinha, J.S.. "Study of polymorphism from DSC melting curves. Polymorphs of terfenadine". Journal of Thermal Analysis and Calorimetry 68 2 (2002): 397-412. https://link.springer.com/article/10.1023/A:1016023315613.
    Published • 10.1023/A:1016023315613
Thesis / Dissertation
  1. Sarraguça, Mafalda. "Improved Quality Control of Solid Dosage Forms for the Pharmaceutical Industry with High-Throughput Vibrational Spectroscopy". PhD, Universidade do Porto Faculdade de Farmácia, 2006.
  2. Sarraguça, Mafalda. "Solid state chemistry of betaxolol hydrochloride". Master, Universidade de Coimbra Faculdade de Ciencias e Tecnologia, 2004.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025/09/10 Women in STEM: Past, Present, and Future From molecules to materials: 2nd Workshop on Benchmarking Solid State Properties
COST - European Cooperation in Science and Technology (Bologna, Italy)
2025/04/23 Deep Eutectic Solvents-Mediated Green Extraction for Nanoparticle Encapsulation of Bioactive Compounds LAQV webinar series
LAQV-REQUIMTE (Portugal)
2025/04/03 Nano Delivery Systems based on Therapeutic Deep Eutectic Systems for Enhanced Tuberculosis Treatment Workshop COST ACTION Advance -TB on "Advances in antituberculosis drug development and treatment strategies"
Krakow University (Krakow, Poland)
2025/03/27 Effective Science Communication: Challenges and Insights from COST and Beyond Advance TB workshop on effective communication
COST - European Cooperation in Science and Technology (Brussels, Belgium)
2024/11/13 A sustainable approach to cellulose extraction from wood waste XXVIII Encontro Galego Portugés de Química
Colegio OficiaL de Quimicos da Galicia (Vigo, Spain)
2023/12/14 Therapeutic Liquid Eutectic Solvents in Lipid Nanoparticles as Drug Vehicles – A proof of concept Advances in Nanotechnology: applications on Agriculture and Health
Faculdade de Farmácia da Universidade do Porto
2023/11/22 GREENER Pharmaceuticals for more sustainable healthcare – This is the way! XXVII Encontro Luso Galego de Química
Portuguese Chemical society (Porto, Portugal)
2023/05/17 TOWARDS A GREENER PHARMACEUTICAL INDUSTRY. THIS IS THE WAY! 8 PYCheM
Universidade de Trás-os-Montes e Alto Douro (Vila Real, Portugal)
2022/12/07 Espectroscopia de Infravermelho próximo (NIR) aplicado ao controlo de qualidade de alimentos Webinar Programa de Pós-graduação em Ciência e Tecnologia de Alimentos
Universidade Federal do Pará (Belém, Brazil)
2022/11/24 EXTRACTION OF BIOACTIVE COMPOUNDS FROM GRAPE POMACE USING DEEP EUTECTIC SOLVENTS SIFFUP – Simpósio de Investigação da FFUP
Faculdade de Farmácia da Universidade do Porto (Porto, Portugal)
2022/11/17 Green Chemistry in the pharmaceutical industry XXVI ENCONTRO GALEGO-PORTUGUÉS DE QUÍMICA
Universidade de Santiago de Compostela (Santiago de Compostela, Spain)
2022/02/28 Improvement of pharmaceutical formulations for tuberculosis treatment CA18224 GREENERING Scientific meeting
GREENERING COST Action (CA18224) (Coimbra, Portugal)
2022/02/24 Multicomponent forms to improve active pharmaceutical ingredients physicochemical properties Research Seminar Series - Hilary Term 2021/22
Trinity College Dublin - School of Pharmacy and Pharmaceutical Sciences (Ireland)
2022/02/11 Gender Balance Activities in COST Action CA18112 Webinar COST Action CA 18112 - Mechanochemistry for Sustainable Industry
COST Action 18112
2021/10/08 Mechanochemistry applied to pharmaceutical multicomponent synthesis Greenering Webinar Series - When industry meets academia
COST Action 18224 - Green Chemical Engineering Network towards upscaling sustainable processes
2021/03/25 Practical applications of IR and Raman spectroscopies in multicomponent reactions Training School - Mechanochemistry: from supramolecular to covalent bonds - synthesis and structural characterization
COST Action CA18112 Mechanochemistry for Sustainable Industry (Lisbon, Portugal)
2021/02/15 Solids turn into liquids. Eutectic mixtures of pharmaceutics to improve drug solubility 1st GREENERING International Conference
GREENERING COST Action (CA18224) (Almada)
2020/07/10 Multivariate Data Analysis in Co-Crystals Development Webinar COST Action CA 18112 - Mechanochemistry for Sustainable Industry
COST Action 18112
2020/02/13 Cocrystallization of olanzapine a way to improve chemical and physical stability IJUP 2020- Thirteenth Meeting of YoungResearcher of University of Porto.©
University of Porto (Portugal, Portugal)
2019/11/26 Cocrystallization of olanzepine a way to improve chemical and physical stability SIFFUP - Research symposium
Students Association Pharmacy Faculty, University of Porto (Porto, Portugal)
2018/11 Hydrochlorothiazide cocrystals screening: a vibrational spectroscopy study XXIVMeeting Galitian-Portuguese of Chemistry
National Portuguese Chemical Society (SPQ) (Porto, Portugal)
2018/04 Dynamic modelling of granules size distribution produced by a continuous manufacturing process with autoregressive neural networks EuPAT 9 - Nineth pan-European QbD &PAT Science Conference European
European Federation for Pharmaceutical Sciences (EUFEPS) (Manchester, United Kingdom)
2018/03 NIR and Raman spectroscopy as tools to assure olanzapine stability in formulations 11th, World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology
International Association for Pharmaceutical Technology (Granada, Spain)
2017/11 New hydrochlorothiazide cocrystals: scale-up and charcterization XXII Meeting Galitian-Portuguese of Chemistry
Colegio Oficial De Químicos da Galicia (Ferrol, Spain)
2017/02 Determination of zonisamide in human plasma using microextraction by packed sorbent and high performance liquid chromatography-diode array detection XLVII Anual Metting of the Portuguese Farmacology Society
Portuguese Farmacology Society (Coimbra, Portugal)
2016/11 Synthesis and characterization of pharmaceutical cocrystals of glibenclamide and gliclazide XXII Meeting Galitian-Portuguese of Chemistry
Portuguese Society of Chemistry (SPQ) (Bragança, Portugal)
2016/10 Batch statistical process control of cocrystallization processes: a comparison between PLS and OPLS EuPAT 8 - Eigth pan-European QbD & PAT Science Conference
European Federation for Pharmaceutical Sciences (EUFEPS) (Cork, Ireland)
2016/06 Comparison between PLS and OPLS to batch process monitoring of cocrystallization processes 8º Meeting of Analytical Chemistry Division
Portuguese Chemical Society (Lisboa, Portugal)
2015/11 Vibrational spectroscopy applied to the synthesis and characterization of pharmaceutical cocrystals with industrial relevance III NUPFARQ Symposium
Maranhão Federal University (Imperatriz, Brazil)
2015/06 Furosemide and p-aminobenzoic acid cocrystals. A near infrared spectroscopy study XXIV Meeting of the National Portuguese Chemical Society
Portuguese Chemical Society (SPQ) (Coimbra, Portugal)
2015/05 Near infrared spectroscopy as a PAT tool to monitor cocrystallizations EuPAT 7- Seventh pan-European QbD & PAT Science Conference
European Federation for Pharmaceutical Sciences (EUFEPS) (Graz, Austria)
2014/09 Near infrared spectroscopy as a PAT tool to monitor online cocrystallizations 8th Annual Symposium of Pharmaceutical Solid State Research Cluster (PSSRC)
University of Ljubljana (Ljubljana, Slovenia)
2014/04 Optimizing multivariate regression models based on heterogeneous samples near infrared spectra 6º Meeting of Analytical Chemistry Division
Portuguese Chemical Society (SPQ) (Coimbra, Portugal)
2011/11 Differentiation of Acinetobacter spp. with intrinsic fluorescence spectroscopy XVII Meeting Galitian-Portuguese of Chemistry
Colegio Oficial De Químicos da Galicia (Pontevedra, Spain)
2011/06 A batch modelling approach to monitor a freeze-drying process using in-line Raman spectroscopy 3rd PharmSciFair
European Federation for Pharmaceutical Sciences (EUFEPS) (Praga, Czech Republic)
2010/11 High-throughput pharmaceutical process quality control (PAT/QbD): a challenge for analytical chemistry V Congresso Iberoamericano de Química Analítica X Encuentro Nacional de Química Analítica y Ambiental
(Concón, Chile)
2010/06 Bioreactor monitoring with spectroscopy and chemometrics: a review VII Colloquium Chemiometricum Mediterraneum
Granada University (Granada, Spain)
2009/11 NIR as a multitasking technique in the pharmaceutical field 14th Internatioanal Conference on Near Infrared Spectroscopy
International Council for Near Infrared Spectroscopy (Banguecoque, Thailand)
2008/09 High-throughput pharmaceutical process monitoring: integrating the hardware and software components 10th International Chemical & Biological Engineering Conference
Minho University (Braga, Portugal)
2008/06 High-throughput pharmaceutical process quality control (PAT): practical implementations and revenue 19th International Symposium on Pharmaceutical and Biomedical Analysis
Pharmaceutical and Biomedical Analysis Steering Commitiee (Gdansk, Poland)
2007/06 Chemometrics in NIR spectroscopy pharmaceutical applications 13th Internatioanal Conference on Near Infrared Spectroscopy
International Council for Near Infrared Spectroscopy (Umea, Sweden)
2007/03 Chemometrics in vibrational spectroscopy pharmaceutical applications 6º Meeting of Analytical Chemistry Division
Portuguese Chemical Society (SPQ) (Lisboa, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2025/03/01 - Current Post-Doctoral Fellow hired under project IMPACTIVE (reference nº: 101057286)
Co-supervisor of Ricardo Teixeira
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2024/07/01 - Current Post-Doctoral Fellow hired under project IMPACTIVE (reference nº: 101057286)
Co-supervisor of Jorge Dourado
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2024/04/01 - Current Post-Doctoral Fellow hired under project IMPACTIVE (reference nº: 101057286)
Co-supervisor
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2023/06/01 - Current Post-Doctoral Fellow hired under project IMPACTIVE (reference nº: 101057286)
Co-supervisor of Ana Carina Sobral Carvalho
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2025/02/10 - 2025/07/24 Nanoparticle-Based Delivery of Therapeutic Deep Eutectic Systems for Tuberculosis Treatment
Supervisor of Evelina Karlsson de Aguiar Quintas
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2025/02/10 - 2025/07/24 Utilização de Solventes Eutécticos Profundos para a Extração Assistida por Micro-Ondas de Celulose a partir de Amostras de Madeira
Co-supervisor of Pedro Castanheira Silva Sousa
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/09/01 - 2023/07/25 Extração de compostos bioativos do bagaço de uva com recurso a solventes eutécticos profundos.
Supervisor of Cátia Ferreira
 Controlo da Qualidade (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/02/02 - 2022/09/13 Desenvolvimento de solventes verdes para utilização na indústria farmacêutica
Supervisor of Catarina Filipa Martins Carvalho
 Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/02/01 - 2022/07/25 Therapeutic Liquid Eutectic Systems as a drug vehicle for tuberculosis treatment
Supervisor of Cláudia Isabel Vareiro Marques
 Bioquímica (Degree)
Universidade do Porto Faculdade de Farmácia, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
2020/09/01 - 2022/07/22 Development of green solvents for the pharmaceutical industry
Supervisor of Constatino Coelho
 Controlo de Qualidade (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/07/10 - 2022/06 Curso Secundário com Planos Próprios de Análises Químico-Biológicas
Supervisor of David Moreira
 Planos Próprios de Análises Químico-Biológicas (Specialization course)
Universidade do Porto Faculdade de Farmácia, Portugal

Colégio de Gaia, Portugal
2021/09/01 - 2022/02/11 Melhoramento de formulações farmacêuticas para o tratamento da tuberculose em crianças
Supervisor of Helena Sofia Ribeiro Monteiro
 Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/11 - 2021/07 Enhancement of pharmaceutical formulations for the tratment of tubercolosis in children
Supervisor of Joana Catarina Martins Gonçalves
 Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/09 - 2021/02/08 Synthesis of new multicomponent forms of the drug (S,S)-Ethambutol
Supervisor of Rafael Gomes
 Mestrado Integrado em Ciências Farmacêuticas (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/11/01 - 2020 Thermal study of the cocrystals of Glibenclamide
Supervisor of Ana Beatriz Almeida
Ciências Farmacêuticas (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/09 - 2019/11 Development of sweet cocrystals for pharmaceutical applications
Supervisor
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Faculdade de Farmácia, Portugal
2019/02/12 - 2019/07/31 Study of new co-amorphous materials
Supervisor of Luís Diogo Pinheiro
Ciências Farmacêuticas (Scientific initiation)
Universidade do Porto Faculdade de Farmácia, Portugal
2016/09 - 2019/07/31 High-throughput screening of hydrochlorothiazide cocrystals by vibrational spectroscopy
Supervisor of Marisa Abreu Rodrigues
 Controlo de Qualidade (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2018/11/01 - 2019/06 Study of glibenclamide p-aminobenzoic acid cocrystals
Supervisor of Rita Lima
 Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/02 - 2018/10/28 Scale-up and high-throughput monitoring of cocrystallisation processes
Co-supervisor of Inês Pecêgo
Engenharia Farmacêutica (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2011/09 - 2017/10/02 Process analytical technology for batch and continuous pharmaceutical process supervision
Co-supervisor of Ana Filipa Tavares da Silva
 Ciências Farmacêuticas (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal

Universiteit Gent, Belgium
2016/02/01 - 2017/09/07 From synthesis to formulation of gliclazide and glibenclamide cocrystal pharmaceutical solid dosage forms
Co-supervisor of Bárbara Violinha Baptista
 Engenharia Farmacêutica (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/09 - 2016/07 On-line monitoring of a cocrystallization process between hydrochlorothiazide and p-aminobenzoic acid using near infrared spectroscopy
Co-supervisor of Carolina Janardo Ribeiro
 Ciências Farmacêuticas (Other)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/09/21 - 2023/09/22 1st year meeting European Project IMPACTIVE (2023/09/21 - 2023/09/22)
Meeting
 Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2022/02/28 - 2022/03/02 CA18224 GREENERING Scientific meeting. This 3-day meeting aims to bring together in person the participants of the Greenering network. After two years of online work, it is our belief that personal connections must be re-established and encouraged. (2022/02/28 - 2022/03/02)
Meeting (Member of the Organising Committee)
 Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2021/02/11 - 2021/02/11 Perspectives on Gender Balance in STEM (online event) - COST Action 18112 MechanoChemistry for Sustainable Industry (2021/02/11 - 2021/02/11)
Round table (Co-organisor)
 European Cooperation in Science and Technology, Belgium
2013/06 - 2013/09/24 Scientific committee member of the EuPAT6 conference (2013/09/22 - 2013/09/24)
Congress (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2001/06 - 2001/09/21 Collaboration on the organization of the XV European Colloid and Interface Society Conference (2001/09/16 - 2001/09/21)
Congress (Other)
 Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2025/07/07 - 2025/07/11 Participation in the Junior University in the Faculty of Pharmacy of the University of Porto, Portugal, in which students from the high school are introduced to research in pharmaceutical sciences.
Other
 Universidade Junior
Universidade do Porto Faculdade de Farmácia, Portugal
2024/07/08 - 2024/07/12 Participation in the Junior University in the Faculty of Pharmacy of the University of Porto, Portugal, in which students from the high school are introduced to research in pharmaceutical sciences. Universidade Junior
Universidade do Porto Faculdade de Farmácia, Portugal
2024/05/22 - 2024/05/23 Defeating tuberculosis: challenges, breakthroughs and lessons learnt from projects including clinical research. Online participation
Workshop
 Defeating tuberculosis: challenges, breakthroughs and lessons learnt from projects including clinical research
Institut de Recerca Germans Trias i Pujol, Spain
2024/05/22 - 2024/05/23 Defeating Tuberculosis: challenges, breakthroughs and lessons learnt from projects including clinical research Workshop
Workshop
 Defeating tuberculosis: challenges, breakthroughs and lessons learnt from projects including clinical research
Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol, Spain
2024/04/08 - 2024/04/08 Seminar from Dr Lucica Ditiu entitled: "Communities, civil society and people with vulnerabilities at the center of TB response - myth or reality?"
Seminar
 Communities, civil society and people with vulnerabilities at the center of TB response - myth or reality?
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024/02/15 - 2024/02/16 Final Meeting of COST Action 18224
Meeting
 Final Meeting of COST Action 18224
European Cooperation in Science and Technology, Belgium
2023/09/21 - 2023/09/22 1st year meeting European Project IMPACTIVE
Meeting
 1st year meeting European Project IMPACTIVE
Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2023/06/22 - 2023/06/23 Workshop of the Final Meeting of COST ACTION CA18112
Workshop
 Workshop of the Final Meeting of COST ACTION CA18112
European Cooperation in Science and Technology, Belgium
2023/02/14 - 2023/02/17 COST Action CA21164 - Towards an improvement in diagnostics and treatment strategies for TB control (ADVANCE-TB) first meeting
Meeting
 Fist meeting CA21164 - Towards an improvement in diagnostics and treatment strategies for TB control (ADVANCE-TB)
European Cooperation in Science and Technology, Belgium
2022/12/20 - 2022/12/20 Conference by Professor Isiah M. Warner, University Cincinnati, USA
Seminar
 Medical Apllications of GUMBOS
Universidade do Porto Faculdade de Farmácia, Portugal
2022/11/07 - 2022/11/08 Kick-off meeting European Project IMPACTIVE DOI 10.3030/101057286
Meeting
 Kick-off meeting European Project IMPACTIVE
Université de Montpellier Département Chimie, France
2022/10/28 - 2022/10/28 The COST Academy will organize a targeted training session on how to integrate a gender dimension in R&I teams
Workshop
 COST Academy – Workshop on Gender equality in research and innovation
European Cooperation in Science and Technology, Belgium

European Commission Joint Research Centre, Belgium
2022/09/12 - 2022/09/13 Encontro Online LAQV REQUIMTE
Meeting
 Encontro Online REQUIMTE
REQUIMTE LAQV Porto, Portugal
2022/06/10 - 2022/06/10 "Mechanochemistry meets Industry” (2nd Edition) Economic consideration and business perspective
Workshop
 Mechanochemistry meets Industry
Università degli Studi di Cagliari Dipartimento di Ingegneria Civile Ambientale e Architettura, Italy
2021/09 - 2022/04 The University of Porto presents the Introduction to University Teaching initiative, a Training Cycle aimed at teachers at the beginning of their careers. The course 15 modules with a duration of 77 hours.
Workshop
 Introdução à docência universitária - ciclo de formações da U.Porto
Universidade do Porto, Portugal
2022/02/28 - 2022/03/02 CA18224 GREENERING Scientific meeting
Meeting
 CA18224 GREENERING Scientific meeting
COST Action 18224 - Green Chemical Engineering Network towards upscaling sustainable processes, Portugal
2021/11/04 - 2021/11/04 Pedagogic conference Pharmacy Faculty, University of Porto
Conference
 Pedagogic conference Pharmacy Faculty, University of Porto
Universidade do Porto Faculdade de Farmácia, Portugal
2021/02/17 - 2021/02/18 Mechanochemistry Meets Industry - Mechanochemistry for Sustainable Industry - online event - COST Action CA18112 - strives to advance cooperation between industrial partners and academic researchers to facilitate integration of mechanochemistry into chemical processes at both R&D phase and production scale.
Symposium
 Mechanochemistry Meets Industry
European Cooperation in Science and Technology, Belgium
2020/09/17 - 2020/09/18 Encontro Online REQUIMTE
Meeting
 Encontro Nacional REQUIMTE
REQUIMTE LAQV Porto, Portugal
2020/02/17 - 2020/02/18 1st Join meeting COST Action CA18224
Meeting
 1st Join meeting COST Action CA18224
COST Action 18224 , Portugal
2019/10/21 - 2019/10/25 Modern Methods of Structure Elucidation (MMSE) is the annual national training site on modern spectroscopic analytical techniques intended for Bachelor, Master and Ph.D. Students, Post-docs and Young Researchers from the Universities, as well as Researchers/Spectroscopists from the Industrial Laboratories across the country. This event is organized by the Centro de Química Estrutural – Instituto Superior Técnico – Universidade de Lisboa (CQE–IST), in collaboration with the IST/ITN .
Workshop
 National Training Site on Modern Methods of Structure Elucidation - 2019
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017/04/06 - 2017/04/06 Seminar Retsch – The art of grinding and dynamic image analysis
Seminar
 The art of grinding and dynamic image analysis
Retsch GmbH, Germany
2016/02/04 - 2016/02/05 Encontro REQUIMTE
Meeting
 Encontro Nacional do REQUIMTE
REQUIMTE LAQV Porto, Portugal
2015/09/13 - 2015/09/13 Seminary in XRD solutions
Seminar
 ECS Transactions
Paralab, Portugal
2015/05/05 - 2015/05/05 Seminary, BTC Europe
Seminar
 BTC Customer seminar
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015/02/25 - 2015/02/25 Conference in Nanoparticles in modern analytical chemistry
Conference
 Nanoparticles in modern analytical chemistry
Universidade do Porto Faculdade de Farmácia, Portugal
2013/04/02 - 2013/04/02 Conference in Biodisel
Conference
 Conference in Biodisel in Brazil
Universidade do Porto Faculdade de Farmácia, Portugal
2008/05/20 - 2008/05/20 Seminary Ecoanalytix.
Seminar
 Seminary Ecoanalytix
PerkinElmer Inc, United States
2006/11/20 - 2006/11/22 Workshop in Pharmaceutical Quality Management
Workshop
 Workshop in Pharmaceutical Quality Management
Ordem dos Farmaceuticos, Portugal
2006/10/24 - 2006/10/24 Hands-on workshop on FTIR, NIR, Raman and TD-NMR
Workshop
 Hands-on workshop on FTIR, NIR, Raman and TD-NMR
Bruker Optics Inc, United States
2006/01/02 - 2006/04/30 Post-graduation in Entrepreneurship and Business Management
Other
 Entrepreneurship and Business Management
Centro de Emprego e Formação Profissional , Portugal
2003/04 - 2003/06 Post-graduation in Quality Management System
Other
 Quality Management System
AEMITEQ - Associação Para A Inovação Tecnologica E Qualidade, Portugal
2003/01 - 2003/03 Post-graduation in chemical quality control of water
Other
 Chemical quality control of water
AEMITEQ - Associação Para A Inovação Tecnologica E Qualidade, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2025/07/24 Utilização de Solventes Eutécticos Profundos para a Extração Assistida por Micro-Ondas de Celulose a partir de Amostras de Madeira
Supervisor
 Pedro Castanheira Silva Sousa (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2025/07/24 Nanoparticle-Based Delivery of Therapeutic Deep Eutectic Systems for Tuberculosis Treatment
Supervisor
 Evelina Karlsson de Aguiar Quintas (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2025/06/26 Tailoring GUMBOS for Enhanced Antibacterial Potency: Synthesis, Characterization and Biological Insights
(Thesis) Arguer
 Fábio Miguel Santos Costa (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2025/03/24 Enable the Development of Dissolution Models as a Path to Real Time Release Testing in Continuous Manufacturing Environment
(Thesis) Main arguer
 Sara Campelos Batista (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/12/06 Optimizing Blending Processes: Establishing and Refining NIR and Transmission Raman methods
(Thesis) Main arguer
 Jacinta Dias Ribeiro (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2024/07/24 Development of a resveratrol solid dispersion with enhanced oral bioavailability by the lyophilization method
(Thesis) Arguer
 Hugo Miguel Ferreira Almeida (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/10/19 Caracterização dos resíduos provenientes da indústria vinícola e potencial aplicação em produtos alimentares
(Thesis) Main arguer
 EDUARDA MANUELA PINHEIRO FERREIRA (Master)
Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal
2023/07/24 Extração de compostos bioativos do bagaço de uva com recurso a solventes eutécticos profundos
Supervisor
 Cátia Carvalho Ferreira (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2023/07/21 Uso de nanopartículas poliméricas para entrega de fármacos para terapia fotodinâmica de cancro de figado
(Thesis) Arguer
 Mariana Fernando Moreira (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2023/04/17 Solventes eutécticos profundos para a extração de compostos bioativos naturais. Aplicações na indústria cosmética. - Seminario de Mestrado
Supervisor
 Cátia Ferreira (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/07/25 Therapeutic deep eutectic systems as a drug vehicule for tuberculosis treatmentr
Supervisor
 Cláudia Marques (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/07/22 Implementation of green chemistry in the pharmaceutical industry. New challenges for the XXI century.
Supervisor
 Constantino Coelho (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/07/20 FTIR-ATR analysis of Covid-19 blood plasma for immunological biochemical indicators estimation
(Thesis) Main arguer
 Alexandra Raquel Moreira Martins (Other)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2022/07/13 Development of green solvents for pharmaceutical industry
Supervisor
 Catarina Carvalho (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/02/11 Melhoramento de formulações farmacêuticas para o tratamento da tuberculose em crianças
Supervisor
 Helena Sofia Ribeiro Monteiro (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/11/18 A reverse engineering approach for the quantitative evaluation of a liquid dosage form using FT-IR spectroscopy and chemometric tools
(Thesis) Main arguer
 Carolina Mendes Oliveira (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2021/10/05 Development of a Resveratrol Solid Dispersion with Enhanced Oral Bioavailability by the Lyophilization Method
(Thesis) Main arguer
 Hugo Miguel Ferreira Almeida (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/07/22 IONIC LIQUIDS, GUMBOS AND NANOGUMBOS AS STRATEGY TO CONTROL ANTIMICROBIAL RESISTANCE
(Thesis) Main arguer
 Fábio Miguel Santos Costa (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2021/05/07 Improvement of pharmaceutical formulations for tubercolosis treatment
Supervisor
 Joana Catarina Martins Gonçalves (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/02/08 Synthesis of new multicomponent forms of the drug (S,S)-Ethambutol
Supervisor
 Rafael Silveira Gomes (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/11/26 Quality Risk Management, its tools and practical applications
(Thesis) Main arguer
 Rui Miguel Oliveira Ferro (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/07/31 High-throughput screening of hydrochlorothiazide cocrystals by vibrational spectroscopy
Supervisor
 Marisa Abreu Rodrigues (Master)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/06 Study og glibenclamide p-aminobenzoic acid cocrystals
Supervisor
 Rita Lima (Other)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/04/11 Monitorização de conversões polimórficas em formulações de olanzepina através de espectroscopia vibracional
(Thesis) Main arguer
 Cláudia Filipa Abreu Miranda (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/10 Mathematical Modelling for Development, Scale-up and Optimization of a process of Lyophilization
(Thesis) Main arguer
 Mauro Duarte (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/10 Multivariate analysis of a direct compression pharmaceutical tablets continuous manufacturing process
(Thesis) Main arguer
 Sílvia Miranda (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018/02/28 Monitorização da qualidade de papas infantis por espetroscopia de infravermelho próximo
(Thesis) Main arguer
 Ana Telma da Silva Pereira Leal (Other)
Universidade do Porto Faculdade de Farmácia, Portugal
2017/01/19 A continuous manufacturing model for the production of granules by roller compaction
(Thesis) Main arguer
 Rute Sofia Fonseca Cordeiro Dias (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/12 Intrinsic fluorescence in the discrimination of Acinetobacter calcoaceticus-Acinetobacter baumannii complex species
(Thesis) Main arguer
 Ana Sofia Rodrigues de Oliveira e Silva (Master)
Universidade do Minho, Portugal
2016/11/28 Análise e Caracterização de Tintas de Instrumentos Manuais de Escrita por Espetroscopia de Raman
(Thesis) Main arguer
 Patrícia Alexandra de Araújo Pereira (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/06/27 Evaluation of the cost-benefit of the implementation of PAT systems for the production of solid forms in the pharmaceutical industry
(Thesis) Main arguer
 Pedro Miguel António Cordeiro (Master)
Universidade de Lisboa Faculdade de Farmácia, Portugal

Ad Hoc journal article review

Journal title (ISSN) Publisher
2024/04 - Current Biotechnology Advances Elsevier
2024/04 - Current Jornal da Sociedade Portuguesa de Química Sociedade Portuguesa de Química
2021/11 - Current PLOS One ( 1932-6203) PLOS
2021/09 - Current Molecules (1420-3049) MDPI AG
2021/02/10 - Current Pharmaceuticals (1424-8247) MDPI AG
2021/02 - Current Jornal of Food Composition and Analysis (0889-1575) Elsevier
2021/02 - Current Current Research in Chemical Biology ( 2666-2469) Elsevier
2020/09/15 - Current Processes (2227-9717) MDPI AG
2020/09/14 - Current Molecular Biomedicine (2662-8651) Springer
2020/09/01 - Current ACS Omega (2470-1343) American Chemical Society
2020/07/21 - Current Journal of Chemical Information and Modeling (1549-9596) ACS Publications
2020/05/26 - Current Journal of Drug Delivery Science and Technology (1773-2247) Elsevier
2019/10/14 - Current French-Ukrainian Journal of Chemistry (2312-3222) Taras Shevchenko National University of Kyiv
2019/10/09 - Current Scientific Reports (2045-2322) Springer Science and Business Media LLC
2019/09/13 - Current MethodsX (2215-0161) Elsevier
2019/03/01 - Current European Journal of Pharmaceutical Sciences (0928-0987) Elsevier
2019/02/25 - Current Food Chemistry (0308-8146) Elsevier
2019/01/25 - Current Pharmaceutics (1999-4923) MDPI AG
2018/11/30 - Current Food Research International (0963-9969) Elsevier
2018/11/04 - Current Drug Development and Industrial Pharmacy (1520-5762) Informa UK (Taylor & Francis)
2018/06/25 - Current Chemometrics and Intelligent Laboratory Systems (0169-7439) Elsevier
2018/02/27 - Current International Journal of Pharmaceutics (0378-5173) Elsevier
2018/02/14 - Current Applied Sciences (2076-3417) MDPI
2017/11/06 - Current Journal of Pharmaceutical and Biomedical Analysis (0731-7085) Elsevier
2017/09/21 - Current Journal of Food Science (1750-3841) Wiley (Blackwell Publishing)
2017/07/24 - Current Sensors (1424-8220) MDPI AG
2017/03/27 - Current Journal of Food Process Engineering (1745-4530) Wiley (Blackwell Publishing)
2017/01/20 - Current Environmental Science and Pollution Research (1614-7499) Springer-Verlag
2016/05/27 - Current RSC Advances (2046-2069) The Royal Society of Chemistry
2016/03/15 - Current Food Analytical Methods (1936-976X) Springer-Verlag
2012/02/10 - Current Industrial & Engineering Chemistry Research (1520-5045) American Chemical Society
2018/01 - 2018/01 Vibrational Spectroscopy for Plant Varieties and Cultivars Characterization (978-0-444-64048-2) Elsevier B.V.

Association member

Society Organization name Role
2024/11/01 - Current Portuguese Chemical Society Member
2021 - Current Portuguese Society of Pharmaceutical Sciences Member

Committee member

Activity description
Role 		Institution / Organization
2023/03 - Current Core Group Member COST ACTION CA18224- Green Chemical Engineering Network towards upscaling sustainable processes
Member
 European Cooperation in Science and Technology, Belgium
2023/02 - Current WG4 leader CA 18224 - Green Chemical Engineering Network towards upscaling sustainable processes
Coordinator
 European Cooperation in Science and Technology, Belgium
2022/09/29 - Current Member of COST Action CA21164 - Towards an improvement in diagnostics and treatment strategies for TB control (ADVANCE-TB)
Member
 European Cooperation in Science and Technology, Belgium
2023/10/02 - 2027/09/17 Member of COST Action CA22107 - Bringing Experiment and Simulation Together in Crystal Structure Prediction (BEST-CSP)
Member
 European Cooperation in Science and Technology, Belgium
2020/10/01 - 2023/08/28 Gender Balance Co-Leader of COST Action CA18112 - Mechanochemistryfor Sustainable Industry
Member
 European Cooperation in Science and Technology, Belgium
2020/02/01 - 2023/08/28 Member of COST Action CA18112 - Mechanochemistry for Sustainable Industry
Member
 European Cooperation in Science and Technology, Belgium

Conference scientific committee

Conference name Conference host
2022/02/28 - 2022/03/02 GREENERING Scientific meeting GREENERING COST Action (CA18224)
2013/07 - 2013/08 EuPAT 6 - Sixth pan-European QbD &PATScience Conference European Porto, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022/02 - 2024/07 Physical-Chemistry Ciências Farmacêuticas (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal
2022/09 - 2023/02 General and Inorganic Chemistry Ciências Farmacêuticas (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal
2020/12/04 - 2020/12/04 Métodos Instrumentais de Analise I - theoretical lesson nº 21 Raman spectoscopy - theroy and applications Ciências Farmacêuticas (Mestrado integrado) Universidade do Porto Faculdade de Farmácia, Portugal
2018/04/01 - 2019/04 Process Analytical Tecnology - PAT Engenharia Farmacêutica (Mestrado) Universidade de Lisboa Instituto Superior Técnico, Portugal

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2022/09/01 - Current Editorial Board Member Drugs and Drug Candidate
Member
 Multidisciplinary Digital Publishing Institute AG, Switzerland
2022 - Current Reviewer Editor of Frontiers in Analytical Sciences - section- Chemometrics
Evaluator
 Frontiers Media SA, Switzerland
2020/03 - Current Reviewer board of the Journal Pharmaceutics
Other
 Multidisciplinary Digital Publishing Institute AG, Switzerland
2020/01 - Current Section Board Member of the Journal Pharmaceuticals
Member
 Multidisciplinary Digital Publishing Institute AG, Switzerland
2019 - Current Evaluation of the National Research Agency (ANR) generic call 2019 as a Scientific Expert
Evaluator
 Agence nationale de la recherche, France Agence nationale de la recherche
2023/06 - 2025/04/25 Guest Editor of Pharmaceuticals- Special Issue: 20th Anniversary of Pharmaceuticals -Green Techniques for Organic and Organometallic/Coordination Synthesis and Medicinal Chemistry) Multidisciplinary Digital Publishing Institute AG, Switzerland
2022/09/01 - 2024/02/29 Guest Editor of Molecules: Special Issue: "Mechanochemistry: New Perspective of Green Chemistry"
Coordinator
 Multidisciplinary Digital Publishing Institute AG, Switzerland
2020/03 - 2020/11/30 Guest Editor of Crystals - Specila Issue: "The Realm of Pharmaceutical Multicomponent Forms"
Coordinator
 Multidisciplinary Digital Publishing Institute AG, Switzerland

Mentoring / Tutoring

Topic Student name
2025/02/10 - 2025/07/15 Improving the solubility of quercetin in deep eutectic solvents Ricardo Costa
2024/09/30 - 2024/12/30 Incorporation of anti-tuberculosis drugs based deep eutectic solvents into lipidic nanoparticles. Sevin Üner
2021/09/07 - 2021/09/30 Green Solvents for pharmaceutical applications: Ioanna Kostopoulou
2020/02 - 2020/06 Solubilidade e biodisponibilidade de fármacos sólidos: como melhorar estas propriedades? Ricardo Nave Isaías
2020/02 - 2020/06 Como melhorar a solubilidade e biodisponibilidade de fármacos sólidos? Sara Margarida dos Santos Silva
2019/09/30 - 2019/11/22 Development of sweet cocrystals Miguel Moreira
2019/04/01 - 2019/07/31 Multiple curve resolution for cocrystal purity determination Ana Luiza Pinto Queiroz
2018/02/19 - 2018/02/23 Application of chemometrics and PAT strategy in industrial pharmacy Joanna Ronowicz
2017/09 - 2017/09 Chemometrics in pharmaceutical applications Basma Mohamed Eltanany
2012/09/01 - 2013/11/19 In-situ dissolution testing monitoring of pharmaceutical solid dosage forms by near infrared spectroscopy Ana Rita Matias
2011/01/02 - 2013/07 Manufacturing process and quality control of solid dosage forms optimization for the pharmaceutical industry by near infrared spectroscopy Raquel Queiroz Portela Mendes de Figueiredo
2012 - 2012 Implementation of process analytical technology systems in pharmaceutical production processes Annelies Dhaese
2011 - 2011 Intrinsic fluorescence spectroscopy for differentiating different acinetobacter species/subspecies using multivariate data analysis Lien Mahy
2007 - 2008 Advanced control of Pharmaceutical specialties with near infrared spectrosocopy Ana Isabel de Vasconcelos Cruz
2007 - 2008 Advanced control of pharmaceutical specialties with near-infrared spectroscopy and chemometrics Sandra Liliana de Oliveira Soares

Other jury / evaluation

Activity description Institution / Organization
2023/06/28 - 2023/06/28 Evaluation of a Pos-Doc grant reference IST-ID BL: 161/2023 Associação do Instituto Superior Técnico para a Investigação e Desenvolvimento, Portugal
2023/05/02 - 2023/05/02 Evaluation of a research grant, reference REQUIMTE 2023_22 Universidade do Porto Faculdade de Farmácia, Portugal
2022/04/06 - 2022/04/06 International call for PhD holder Researchers, under a work contract for a non-fixed term for 1 (one) research position (Referência REQUIMTE 2022-13), to pursue scientific research activities in the EXPL/NAN-MAT/0743/2021, HONEY2KILL- Honey-exosomes to fight superbugs project. REQUIMTE LAQV Porto, Portugal
2019/09/09 - 2019/09/09 Evaluation of a research Scholarship for a student with a Master degree. Reference ICETA 2019-65 Universidade do Porto Faculdade de Farmácia, Portugal

REQUIMTE LAQV Porto, Portugal
2016 - 2016 Evaluation of a research Scholarship for a student with a Master degree. Reference ICETA 2019-65
Distinctions

Other distinction

2022 2022.01388.CEECIND
Fundação para a Ciência e a Tecnologia, Portugal
2010 Post-Doc grant (SFRH/BPD/74788/2010)
Fundação para a Ciência e a Tecnologia, Portugal
2006 PhD scholarship (SFRH / BD / 32614 / 2006)
Fundação para a Ciência e a Tecnologia, Portugal
2001 Research Grant (PRAXIS/QUI/10137/98)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal