Artigo em revista |
- Gouveia, Maria João; Ribeiro, Eduarda; Vale, Nuno. "A Surprising Repurposing of Central Nervous System Drugs against Squamous
Cell Carcinoma of the Bladder, UM-UC-5". Pharmaceutics 16 2 (2024): 212. http://dx.doi.org/10.3390/pharmaceutics16020212.
Publicado • 10.3390/pharmaceutics16020212
- da Costa, José Manuel Correia; Gouveia, Maria João; Rinaldi, Gabriel; Brindley, Paul J.; Santos, Júlio; Santos, Lúcio Lara.
"Control Strategies for Carcinogenic-Associated Helminthiases: An Integrated Overview". Frontiers in Cellular and Infection
Microbiology 11 (2021): http://dx.doi.org/10.3389/fcimb.2021.626672.
Publicado • 10.3389/fcimb.2021.626672
- Mariana Pereira; Guy Caljon; Maria Gouveia; Louis Maes; Nuno Vale. "Synthesis, Biological Activity and In Silico Pharmacokinetic
Prediction of a New 2-Thioxo-Imidazoldidin-4-One of Primaquine". Pharmaceuticals (2021): https://www.mdpi.com/1424-8247/14/3/196.
10.3390/ph14030196
- Lúcio Lara Santos; Júlio Santos; Maria Gouveia; Carina Bernardo; Carlos Lopes; Gabriel Rinaldi; Paul J. Brindley; José M.
Correia da Costa. "Urogenital Schistosomiasis—History, Pathogenesis, and Bladder Cancer". Journal of Clinical Medicine
(2021): https://www.mdpi.com/2077-0383/10/2/205.
10.3390/jcm10020205
- Vale, Nuno; Duarte, Diana; Silva, Sara; Correia, Ana Salomé; Costa, Bárbara; Gouveia, Maria João; Ferreira, Abigail. "Cell-penetrating
peptides in oncologic pharmacotherapy: A review". Pharmacological Research 162 (2020): 105231. http://dx.doi.org/10.1016/j.phrs.2020.105231.
Publicado • 10.1016/j.phrs.2020.105231
- Bernardo, Carina; Santos, Júlio; Costa, Céu; Tavares, Ana; Amaro, Teresina; Marques, Igor; Gouveia, Maria João; et al. "Estrogen
receptors in urogenital schistosomiasis and bladder cancer: Estrogen receptor alpha-mediated cell proliferation". Urologic
Oncology: Seminars and Original Investigations 38 9 (2020): 738.e23-738.e35. http://dx.doi.org/10.1016/j.urolonc.2020.04.022.
Publicado • 10.1016/j.urolonc.2020.04.022
- Gouveia, Maria João; Brindley, Paul J.; Gärtner, Fátima; Vale, Nuno. "Activity of Combinations of Antioxidants and Anthelmintic
Drugs against the Adult Stage of Schistosoma mansoni". Journal of Parasitology Research 2020 (2020): 1-9. http://dx.doi.org/10.1155/2020/8843808.
Acesso aberto • Publicado • 10.1155/2020/8843808
- Vale, Nuno; Gouveia, Maria João; Gärtner, Fátima; Brindley, Paul J. "Oxysterols of helminth parasites and pathogenesis of
foodborne hepatic trematodiasis caused by Opisthorchis and Fasciola species". Parasitology Research 119 5 (2020): 1443-1453.
http://dx.doi.org/10.1007/s00436-020-06640-4.
Publicado • 10.1007/s00436-020-06640-4
- Vale, Nuno; Gouveia MJ; Gärtner, Fátima. "Current and Novel Therapies Against Helminthic Infections: The Potential of Antioxidants
Combined with Drugs". Biomolecules 10 3 (2020): 350. http://dx.doi.org/10.3390/biom10030350.
Publicado • http://dx.doi.org/10.3390/biom10030350
- Yang, Vítor; Gouveia, Maria João; Santos, Joana; Koksch, Beate; Amorim, Irina; Gärtner, Fátima; Vale, Nuno. "Breast cancer:
insights in disease and influence of drug methotrexate". RSC Medicinal Chemistry 11 6 (2020): 646-664. http://dx.doi.org/10.1039/d0md00051e.
Publicado • 10.1039/d0md00051e
- Gouveia, Maria João; Pakharukova, Maria Y.; Rinaldi, Gabriel; Mordvinov, Viatcheslav A.; Brindley, Paul J.; Gärtner, Fátima;
Vale, Nuno. "Helminth infection-induced carcinogenesis: spectrometric insights from the liver flukes, Opisthorchis and Fasciola".
Experimental Results 1 (2020): http://dx.doi.org/10.1017/exp.2020.38.
Publicado • 10.1017/exp.2020.38
- Gouveia MJ; Brindley, Paul J.; Rinaldi, Gabriel; Gärtner, Fátima; da Costa, José M. C.; Vale, Nuno. "Infection with carcinogenic
helminth parasites and its production of metabolites induces the formation of DNA-adducts". Infectious Agents and Cancer
14 1 (2019): http://dx.doi.org/10.1186/s13027-019-0257-2.
Acesso aberto • Aceite para publicação • 10.1186/s13027-019-0257-2
- Gouveia MJ; Nogueira, Verónica; Araújo, Bruno; Gärtner, Fátima; Vale, Nuno. "Inhibition of the Formation In Vitro of Putatively
Carcinogenic Metabolites Derived from S. haematobium and O. viverrini by Combination of Drugs with Antioxidants". Molecules
24 21 (2019): 3842. http://dx.doi.org/10.3390/molecules24213842.
Acesso aberto • Aceite para publicação • 10.3390/molecules24213842
- Gouveia MJ; Brindley, Paul J.; Azevedo, Carlos; Gärtner, Fátima; da Costa, José M. C.; Vale, Nuno. "The antioxidants resveratrol
and N-acetylcysteine enhance anthelmintic activity of praziquantel and artesunate against Schistosoma mansoni". Parasites
& Vectors 12 1 (2019): http://dx.doi.org/10.1186/s13071-019-3566-9.
Acesso aberto • Aceite para publicação • 10.1186/s13071-019-3566-9
- Gouveia, Maria João; Brindley, Paul J.; Rinaldi, Gabriel; Gärtner, Fátima; da Costa, José Manuel Correia; Vale, Nuno. "Combination
Anthelmintic/Antioxidant Activity Against Schistosoma Mansoni". Biomolecules 9 2 (2019): 54. http://dx.doi.org/10.3390/biom9020054.
10.3390/biom9020054
- Vale, Nuno; Ferreira, Abigail; Matos, Joana; Fresco, Paula; Gouveia MJ. "Amino Acids in the Development of Prodrugs". Molecules
23 9 (2018): 2318. http://dx.doi.org/10.3390/molecules23092318.
Acesso aberto • 10.3390/molecules23092318
- Gouveia MJ; Brindley, Paul; Gärtner, Fátima; Costa, José; Vale, Nuno. "Drug Repurposing for Schistosomiasis: Combinations
of Drugs or Biomolecules". Pharmaceuticals 11 1 (2018): 15. http://dx.doi.org/10.3390/ph11010015.
Acesso aberto • 10.3390/ph11010015
- Gouveia MJ; Pakharukova, Maria Y; Laha, Thewarach; Sripa, Banchob; Maksimova, Galina A; Rinaldi, Gabriel; Brindley, Paul J;
et al. "Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model". Carcinogenesis
38 9 (2017): 929-937. http://dx.doi.org/10.1093/carcin/bgx042.
Publicado • 10.1093/carcin/bgx042
- Vale, Nuno; Gouveia MJ; Rinaldi, Gabriel; Brindley, Paul J.; Gärtner, Fátima; Correia da Costa, José M.. "Praziquantel for
Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance". Antimicrobial Agents and Chemotherapy
61 5 (2017): http://dx.doi.org/10.1128/aac.02582-16.
Publicado • 10.1128/aac.02582-16
- Vale, Nuno; Gouveia MJ; Rinaldi, Gabriel; Santos, Júlio; Santos, Lúcio Lara; Brindley, Paul J; da Costa, José M Correia. "The
role of estradiol metabolism in urogenital schistosomiasis-induced bladder cancer". Tumor Biology 39 3 (2017): 101042831769224.
http://dx.doi.org/10.1177/1010428317692247.
Publicado • 10.1177/1010428317692247
- Gouveia MJ; Santos, Júlio; Brindley, Paul J.; Rinaldi, Gabriel; Lopes, Carlos; Santos, Lúcio L.; da Costa, José Manuel Correia;
Vale, Nuno. "Estrogen-like metabolites and DNA-adducts in urogenital schistosomiasis-associated bladder cancer". Cancer
Letters 359 2 (2015): 226-232. http://dx.doi.org/10.1016/j.canlet.2015.01.018.
Publicado • 10.1016/j.canlet.2015.01.018
- Correia da Costa, José M.; Vale, Nuno; Gouveia MJ; Botelho, MC; Sripa, Banchob; Santos, Lúcio L.; Santos, Júlio H.; Rinaldi,
Gabriel; Brindley, Paul J.. "Schistosome and liver fluke derived catechol-estrogens and helminth associated cancers". Frontiers
in Genetics 5 (2014): http://dx.doi.org/10.3389/fgene.2014.00444.
Publicado • 10.3389/fgene.2014.00444
- Santos, Júlio; Gouveia MJ; Vale, Nuno; Delgado, Maria de Lurdes; Gonçalves, Ana; da Silva, José M. Teixeira.; Oliveira, Cristiano;
et al. "Urinary Estrogen Metabolites and Self-Reported Infertility in Women Infected with Schistosoma haematobium". PLoS
ONE 9 5 (2014): e96774. http://dx.doi.org/10.1371/journal.pone.0096774.
10.1371/journal.pone.0096774
- Vale, Nuno; Gouveia MJ; Botelho, Mónica; Sripa, Banchob; Suttiprapa, Sutas; Rinaldi, Gabriel; Gomes, Paula; Brindley, Paul
J.; Correia da Costa, José Manuel. "Carcinogenic liver fluke Opisthorchis viverrini oxysterols detected by LC–MS/MS survey
of soluble fraction parasite extract". Parasitology International 62 6 (2013): 535-542. http://dx.doi.org/10.1016/j.parint.2013.08.001.
Publicado • 10.1016/j.parint.2013.08.001
- Gouveia MJ; Brindley, Paul J.; Santos, Lúcio Lara; Correia da Costa, José Manuel; Gomes, Paula; Vale, Nuno. "Mass spectrometry
techniques in the survey of steroid metabolites as potential disease biomarkers: A review". Metabolism 62 9 (2013):
1206-1217. http://dx.doi.org/10.1016/j.metabol.2013.04.003.
10.1016/j.metabol.2013.04.003
- Botelho, Mónica C.; Vale, Nuno; Gouveia MJ; Rinaldi, Gabriel; Santos, Julio; Santos, Lucio L.; Gomes, Paula; Brindley, Paul
J.; Correia da Costa, José Manuel. "Tumour-like phenotypes in urothelial cells after exposure to antigens from eggs of Schistosoma
haematobium: An oestrogen–DNA adducts mediated pathway?". International Journal for Parasitology 43 1 (2013): 17-26.
http://dx.doi.org/10.1016/j.ijpara.2012.10.023.
10.1016/j.ijpara.2012.10.023
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