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Luis Ruano is a Neurology clinical fellow at the Entre o Douro e Vouga Hospital Center since 2016, where he is the head of the Cognition and Dementia Unit. He is an assistant professor of Clinical Epidemiology at the Faculty of Medicine of the University of Porto since 2017. He is an integrated researcher at the Epidemiology Research Unit of the Institute of Public Health of the University of Porto since 2014. He was born in 1984 in Bragança, Portugal. He finished his medical degree at the Abel Salazar Institute of Biomedical Sciences of the University of Porto in 2008. In 2012 he obtained a Master's degree in Public Health at the Faculty of Medicine, University of Porto, with the dissertation "The epidemiology of hereditary ataxias and spastic paraparesis in Portugal", under the supervision of Prof. Paula Coutinho and Prof. Carolina Silva. In 2017 he completed his PhD at the Faculty of Medicine of the University of Porto with the thesis "Improving the understanding of cognitive impairment: Insights from cross-sectional and longitudinal assessment", under the supervision of Prof. Nuno Lunet, Prof. Vítor Tedim Cruz and Prof. Maria Pia Amato. He has published 40 papers in peer-reviewed scientific journals, and co-authored about 20 oral presentations at international conferences and 50 at Portuguese conferences. He has participated as a researcher in 7 funded projects, 2 as principal investigator. His scientific interest is in understanding and modifying the natural history and the determinants of cognitive deterioration in neurodegenerative diseases, cancer and multiple sclerosis. He is currently working in the development of a new approaches for more sensitive and cost effective cognitive screening and monitoring, allowing for a timely diagnosis and improved management strategies for cognitive impairment.
Identificação

Identificação pessoal

Nome completo
Luis Manuel Rebelo Ruano

Nomes de citação

  • Ruano, Luis

Identificadores de autor

Ciência ID
4511-29E4-53A6
ORCID iD
0000-0002-0903-494X
Google Scholar ID
WT8RTZIAAAAJ
Scopus Author Id
55989554100

Endereços de correio eletrónico

  • luis.ruano@chedv.min-saude.pt (Profissional)
  • luisruano@med.up.pt (Profissional)
  • luis.ruano@ispup.up.pt (Profissional)

Telefones

Telefone
  • 222 061 82 (Profissional)

Moradas

  • ISPUP, Rua das Taipas nº135 , 4050-600, Porto, Porto, Portugal (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Clínica - Neurologia Clínica
  • Ciências Médicas e da Saúde - Ciências da Saúde - Epidemiologia
  • Ciências Médicas e da Saúde - Ciências da Saúde - Saúde Pública e Saúde Ambiental

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador independente (B1)
Italiano Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2012/10/01 - 2017/05/02
Concluído
Saúde Pública (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
"Improving the understanding of cognitive impairment Insights from cross-sectional and longitudinal assessment" (TESE/DISSERTAÇÃO)
2013
Concluído
Mestrado em Saúde Pública (Mestrado)
Universidade do Porto Faculdade de Medicina, Portugal
"The epidemiology of hereditary ataxias and spastic paraplegias in Portugal" (TESE/DISSERTAÇÃO)
19
2008
Concluído
Licencitura em Medicina (Licenciatura)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Licenciatura sem tese" (TESE/DISSERTAÇÃO)
13
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2018/09/15 - Atual Professor Auxiliar Convidado (Docente Universitário) Universidade do Porto Faculdade de Medicina, Portugal
2017 - 2018/08/31 Assistente Convidado (Docente Universitário) Universidade do Porto Faculdade de Medicina, Portugal

Outras Carreiras

Categoria Profissional
Instituição de acolhimento
Empregador
2016/09/01 - Atual Assistente (Médica) Centro Hospitalar de Entre o Douro e Vouga EPE, Portugal
2011/01/01 - 2016/06/30 Interno (Médica) Centro Hospitalar de Entre o Douro e Vouga EPE, Portugal
2010/01/01 - 2010/12/31 Interno (Médica) Unidade Local de Saúde do Nordeste EPE, Portugal
Projetos

Projeto

Designação Financiadores
2021 - Atual SMART-HEALTH-4-ALL - Smart medical technologies for better health and care
SMART-HEALTH-4-ALL
Investigador
Universidade do Porto Instituto de Saúde Pública, Portugal

Universidade do Porto Unidade de Investigação em Epidemiologia, Portugal
Autoridade de Gestão do Programa Operacional Competitividade e Internacionalização
Em curso
2021 - 2024/02/29 Neurodegenerative complications after COVID-19
PTDC/SAU-EPI/6275/2020
Investigador responsável
Universidade do Porto Unidade de Investigação em Epidemiologia, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018 - 2022/07/15 Neuro-oncological complications of prostate cancer: longitudinal study of cognitive decline
PTDC/SAU-EPI/32358/2017
Investigador
Universidade do Porto Instituto de Saúde Pública, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2015 - 2020/12/31 Tracking cognitive decline in Multiple Sclerosis
PRT-MSG-14-10645
Investigador responsável
Universidade do Porto Instituto de Saúde Pública, Portugal
Biogen
Concluído
2016 - 2019/11/30 A five-year prospective cohort study on the neurological complications of breast cancer: frequency and impact in patient-reported outcomes
PTDC/DTP-EPI/7183/2014
Investigador
Universidade do Porto Instituto de Saúde Pública, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014 - 2017/06/30 Identification of new causative genes in spinocerebellar degenerations by combination of whole genome scan, next-generation sequencing and biological validation in vitro and in vivo
FCT-ANR/BEX-GMG/0008/2013
Investigador
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em revista
  1. Natália Araújo; Luisa Lopes-Conceição; Samantha Morais; Filipa Fontes; Teresa Dias; Vítor Tedim Cruz; Luís Ruano; Susana Pereira; Nuno Lunet. "Interchangeability of two versions of the Montreal Cognitive Assessment for the longitudinal evaluation of patients with breast cancer". Supportive Care in Cancer (2022): https://doi.org/10.1007/s00520-021-06702-y.
    10.1007/s00520-021-06702-y
  2. Pinto P; Barbosa A; Ruano L; Lunet N. "Assessment of Cancer-related Cognitive Impairment: Methodological Issues.". Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists (2021): http://europepmc.org/abstract/med/31737901.
    10.1093/arclin/acy045
  3. Araujo N; Morais S; Costa AR; Braga R; Carneiro AF; Cruz VT; Ruano L; et al. "Cognitive decline in patients with prostate cancer: study protocol of a prospective cohort, NEON-PC.". BMJ open (2021): http://europepmc.org/abstract/med/33589462.
    10.1136/bmjopen-2020-043844
  4. De Meo E; Portaccio E; Giorgio A; Ruano L; Goretti B; Niccolai C; Patti F; et al. "Identifying the Distinct Cognitive Phenotypes in Multiple Sclerosis.". JAMA neurology (2021): http://europepmc.org/abstract/med/33393981.
    10.1001/jamaneurol.2020.4920
  5. Hendriks, S.; Peetoom, K.; Bakker, C.; Van Der Flier, W.M.; Papma, J.M.; Koopmans, R.; Verhey, F.R.J.; et al. "Global Prevalence of Young-Onset Dementia: A Systematic Review and Meta-analysis". JAMA Neurology 78 9 (2021): 1080-1090. http://www.scopus.com/inward/record.url?eid=2-s2.0-85110480879&partnerID=MN8TOARS.
    10.1001/jamaneurol.2021.2161
  6. Pais, R.; Ruano, L.; Moreira, C.; Fraga, S.; Carvalho, O.P.; Barros, H.. "Social support and cognitive impairment: Results from a portuguese 4-year prospective study". International Journal of Environmental Research and Public Health 18 16 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85113780447&partnerID=MN8TOARS.
    10.3390/ijerph18168841
  7. Araújo, N.; Severo, M.; Lopes-Conceição, L.; Fontes, F.; Dias, T.; Branco, M.; Morais, S.; et al. "Trajectories of cognitive performance over five years in a prospective cohort of patients with breast cancer (NEON-BC)". Breast 58 (2021): 130-137. http://www.scopus.com/inward/record.url?eid=2-s2.0-85107670447&partnerID=MN8TOARS.
    10.1016/j.breast.2021.05.006
  8. Monteiro A; Velon AG; Rodrigues AM; Oliveira A; Valadas A; Nóbrega C; Cruto C; et al. "[Portuguese Consensus on the Diagnosis and Management of Lewy Body Dementia (PORTUCALE)].". Acta medica portuguesa (2020): http://europepmc.org/abstract/med/33496254.
    10.20344/amp.13696
  9. Pais R; Ruano L; Moreira C; Carvalho OP; Barros H. "Prevalence and incidence of cognitive impairment in an elder Portuguese population (65-85¿years old).". BMC geriatrics (2020): http://europepmc.org/abstract/med/33198643.
    10.1186/s12877-020-01863-7
  10. Pais R; Ruano L; P Carvalho O; Barros H. "Global Cognitive Impairment Prevalence and Incidence in Community Dwelling Older Adults-A Systematic Review.". Geriatrics (Basel, Switzerland) (2020): http://europepmc.org/abstract/med/33121002.
    10.3390/geriatrics5040084
  11. Rodrigues R; Branco M; Silva R; Ruano L; Fontão L; Lopes M; Scigliano H; et al. "Peripheral neuropathy in systemic vasculitis and other autoimmune diseases - a report of five cases emphasizing the importance of etiologic characterization.". eNeurologicalSci (2020): http://europepmc.org/abstract/med/32995578.
    10.1016/j.ensci.2020.100272
  12. Luis Ruano; Mariana Branco; Milton Severo; Andreia Sousa; Juliana Castelo; Isabel Araújo; Joana Pais; et al. "Tracking cognitive impairment in multiple sclerosis using the Brain on Track test: a validation study". Neurological Sciences (2020): https://doi.org/10.1007/s10072-019-04088-8.
    10.1007/s10072-019-04088-8
  13. Luis Ruano; Mariana Branco; Milton Severo; Andreia Sousa; Juliana Castelo; Isabel Araújo; Joana Pais; et al. "Correction to: Tracking cognitive impairment in multiple sclerosis using the Brain on Track test: a validation study". Neurological Sciences (2020): https://doi.org/10.1007/s10072-019-04130-9.
    10.1007/s10072-019-04130-9
  14. Melo, C.; Ruano, L.; Jorge, J.; Pinto Ribeiro, T.; Oliveira, G.; Azevedo, L.; Temudo, T.. "Prevalence and determinants of motor stereotypies in autism spectrum disorder: A systematic review and meta-analysis". Autism 24 3 (2020): 569-590. http://www.scopus.com/inward/record.url?eid=2-s2.0-85073946129&partnerID=MN8TOARS.
    10.1177/1362361319869118
  15. Branco, M.; Alves, I.; Martins da Silva, A.; Pinheiro, J.; Sá, M.J.; Correia, I.; Sousa, L.; et al. "The epidemiology of multiple sclerosis in the entre Douro e Vouga region of northern Portugal: a multisource population-based study". BMC neurology 20 1 (2020): 195-195. http://www.scopus.com/inward/record.url?eid=2-s2.0-85084964210&partnerID=MN8TOARS.
    10.1186/s12883-020-01755-8
  16. Rodrigues, R.; Silva, R.; Branco, M.; Brandão, E.; Alonso, I.; Ruano, L.; Loureiro, J.L.. "Determinants of age at onset in a Portuguese cohort of autosomal dominant spastic paraplegia". Journal of the Neurological Sciences 410 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85076910562&partnerID=MN8TOARS.
    10.1016/j.jns.2019.116646
  17. Branco, M.; Ruano, L.; Portaccio, E.; Goretti, B.; Niccolai, C.; Patti, F.; Chisari, C.; et al. "Correction to: Aging with multiple sclerosis: prevalence and profile of cognitive impairment (Neurological Sciences, (2019), 40, 8, (1651-1657), 10.1007/s10072-019-03875-7)". Neurological Sciences 41 1 (2020): 243-243. http://www.scopus.com/inward/record.url?eid=2-s2.0-85075048974&partnerID=MN8TOARS.
    10.1007/s10072-019-04134-5
  18. Luis Ruano; Natália Araújo; Mariana Branco; Rui Barreto; Sandra Moreira; Ricardo Pais; Vítor Tedim Cruz; Nuno Lunet; Henrique Barros. "Prevalence and Causes of Cognitive Impairment and Dementia in a Population-Based Cohort From Northern Portugal". American Journal of Alzheimer's Disease & Other Dementias® 34 1 (2019): 49-56. https://doi.org/10.1177/1533317518813550.
    10.1177/1533317518813550
  19. Souto Silva, R.; Rodrigues, R.; Reis Monteiro, D.; Tavares, S.; Pereira, J.P.; Xavier, J.; Melo, C.; Ruano, L.. "Acute Ischemic Stroke in a Child Successfully Treated with Thrombolytic Therapy and Mechanical Thrombectomy". Case Reports in Neurology (2019): 47-52. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061641259&partnerID=MN8TOARS.
    10.1159/000496535
  20. Rodrigues, R.; Silva, R.; Fontão, L.; Ruano, L.; Roriz, J.M.. "Acute Ischemic Stroke in Pregnancy". Case Reports in Neurology (2019): 37-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061654376&partnerID=MN8TOARS.
    10.1159/000496386
  21. Martins, A.I.; Araujo, I.; Sousa, A.; Ruano, C.; Pais, J.; Félix, S.; Conde, E.; et al. "Long term cognitive monitoring in a community setting: A real-world implementation study,Monitorização cognitiva longitudinal numa comunidade: Estudo de implementação em contexto real". RISTI - Revista Iberica de Sistemas e Tecnologias de Informacao E17 (2019): 499-512. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061212730&partnerID=MN8TOARS.
  22. Ruano, L.; Severo, M.; Sousa, A.; Ruano, C.; Branco, M.; Barreto, R.; Moreira, S.; et al. "Tracking Cognitive Performance in the General Population and in Patients with Mild Cognitive Impairment with a Self-Applied Computerized Test (Brain on Track)". Journal of Alzheimer's Disease 71 2 (2019): 541-548. http://www.scopus.com/inward/record.url?eid=2-s2.0-85072568724&partnerID=MN8TOARS.
    10.3233/JAD-190631
  23. Branco, M.; Ruano, L.; Portaccio, E.; Goretti, B.; Niccolai, C.; Patti, F.; Chisari, C.; et al. "Aging with multiple sclerosis: prevalence and profile of cognitive impairment". Neurological Sciences 40 8 (2019): 1651-1657. http://www.scopus.com/inward/record.url?eid=2-s2.0-85064654217&partnerID=MN8TOARS.
    10.1007/s10072-019-03875-7
  24. Branco M; Rodrigues R; Lopes M; Ruano L. "Cluster-Like Headache Secondary to Sphenoid Sinus Mucocele.". Case reports in neurological medicine (2018): http://europepmc.org/abstract/med/30631616.
    10.1155/2018/5850286
  25. Ruano, L.; Branco, M.; Portaccio, E.; Goretti, B.; Niccolai, C.; Patti, F.; Chisari, C.; et al. "Patients with paediatric-onset multiple sclerosis are at higher risk of cognitive impairment in adulthood: An Italian collaborative study". Multiple Sclerosis Journal 24 9 (2018): 1234-1242. http://www.scopus.com/inward/record.url?eid=2-s2.0-85043346494&partnerID=MN8TOARS.
    10.1177/1352458517717341
  26. Ruano, L.; Branco, M.; Samões, R.; Taipa, R.; Pires, M.M.. "The etiology of spontaneous intracerebralhemorrhage: Insights from a neuropathological series". Clinical Neuropathology 37 1 (2018): 16-21. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042549642&partnerID=MN8TOARS.
    10.5414/NP301051
  27. Ramalho M; Fontes F; Ruano L; Pereira S; Lunet N. "Cognitive impairment in the first year after breast cancer diagnosis: A prospective cohort study.". (2017): http://europepmc.org/abstract/med/28208082.
    10.1016/j.breast.2017.01.018
  28. Ruano, L.; Pereira, S.; Fontes, F.; Ramalho, M.; Lunet, N.. "Reply to H. Ian Robins". Breast 34 (2017): 135-135. http://www.scopus.com/inward/record.url?eid=2-s2.0-85017113326&partnerID=MN8TOARS.
    10.1016/j.breast.2017.03.007
  29. Torres Redondo, M.; Campoa, E.; Ruano, L.; Sucena, M.. "Health-Related Quality of Life in Patients With a1 Antitrypsin Deficency: A Cross Sectional Study,Calidad de vida relacionada con la salud en pacientes con déficit de a1 antitripsina: estudio transversal". Archivos de Bronconeumologia 53 2 (2017): 49-54. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979715886&partnerID=MN8TOARS.
    10.1016/j.arbr.2016.05.013
  30. Ruano L; Portaccio E; Goretti B; Niccolai C; Severo M; Patti F; Cilia S; et al. "Age and disability drive cognitive impairment in multiple sclerosis across disease subtypes.". Multiple Sclerosis 23 9 (2016): 1258-1267. http://europepmc.org/abstract/med/27738090.
    10.1177/1352458516674367
  31. Gouveia A; Dias SP; Santos T; Rocha H; Coelho CR; Ruano L; Galego O; et al. "Cognitive impairment and magnetic resonance imaging correlates in primary progressive multiple sclerosis.". (2016): http://europepmc.org/abstract/med/27778334.
    10.1111/ane.12702
  32. Torres Redondo M; Campoa E; Ruano L; Sucena M. "Health-Related Quality of Life in Patients With a1 Antitrypsin Deficency: A Cross Sectional Study.". (2016): http://europepmc.org/abstract/med/27470706.
    10.1016/j.arbres.2016.05.024
  33. Ruano L; Sousa A; Severo M; Alves I; Colunas M; Barreto R; Mateus C; et al. "Development of a self-administered web-based test for longitudinal cognitive assessment.". (2016): http://europepmc.org/abstract/med/26743329.
    10.1038/srep19114
  34. Ruano L; Melo C; Silva MC; Coutinho P. "The Global Epidemiology of Hereditary Ataxia and Spastic Paraplegia: A Systematic Review of Prevalence Studies.". (2014): http://europepmc.org/abstract/med/24603320.
  35. Tedim Cruz V; Pais J; Ruano L; Mateus C; Colunas M; Alves I; Barreto R; et al. "Implementation and Outcomes of a Collaborative Multi-Center Network Aimed at Web-Based Cognitive Training - COGWEB Network.". (2014): http://europepmc.org/abstract/med/26543902.
    10.2196/mental.3840
  36. Cruz, V.T.; Bento, V.; Ruano, L.; Ribeiro, D.D.; Fontão, L.; Mateus, C.; Barreto, R.; et al. "Motor task performance under vibratory feedback early poststroke: Single center, randomized, cross-over, controled clinical trial". Scientific Reports 4 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84904299383&partnerID=MN8TOARS.
    10.1038/srep05670
  37. Cruz, V.T.; Pais, J.; Alves, I.; Ruano, L.; Mateus, C.; Barreto, R.; Bento, V.; et al. "Web-based cognitive training: Patient adherence and intensity of treatment in an outpatient memory clinic". Journal of Medical Internet Research 16 5 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84902269669&partnerID=MN8TOARS.
    10.2196/jmir.3377
  38. Ruano, L.; Melo, C.; Silva, M.C.; Coutinho, P.. "The global epidemiology of hereditary ataxia and spastic paraplegia: A systematic review of prevalence studies". Neuroepidemiology 42 3 (2014): 174-183. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895587442&partnerID=MN8TOARS.
    10.1159/000358801
  39. Barros, J.; Ruano, L.; Domingos, J.; Tuna, A.; Damásio, J.; Alonso, I.; Silveira, I.; Sequeiros, J.; Coutinho, P.. "The prevalence of familial hemiplegic migraine with cerebellar ataxia and spinocerebellar ataxia type 6 in portugal". Headache 54 5 (2014): 911-915. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899900849&partnerID=MN8TOARS.
    10.1111/head.12260
  40. Coutinho, P.; Ruano, L.; Loureiro, J.L.; Cruz, V.T.; Barros, J.; Tuna, A.; Barbot, C.; et al. "Hereditary ataxia and spastic paraplegia in Portugal: A population-based prevalence study". JAMA Neurology 70 6 (2013): 746-755. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878770734&partnerID=MN8TOARS.
    10.1001/jamaneurol.2013.1707
  41. Loureiro, J.L.; Brandão, E.; Ruano, L.; Brandão, A.F.; Lopes, A.M.; Thieleke-Matos, C.; Miller-Fleming, L.; et al. "Autosomal dominant spastic paraplegias: A review of 89 families resulting from a Portuguese survey". JAMA Neurology 70 4 (2013): 481-487. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876133160&partnerID=MN8TOARS.
    10.1001/jamaneurol.2013.1956
  42. Ruano, Luis. "Superficial Siderosis and Anticoagulation Therapy: Different Presentations, Different Outcomes". (2012):
    10.1155/2012/745430
  43. Ruano, Luis. "Ischemic Vagus Nuclei Lesions and Hyperglycemia: A Study in 26 Patients with Lateral Medullary Infarction and Matched Controls". (2012):
    10.1159/000343654