???global.info.a_carregar???
Luis Filipe Baptista Pleno de Gouveia. Concluiu o Doutoramento em Farmácia em 2003/05/10 pela Universidade de Lisboa. É Professor Auxiliar na Universidade de Lisboa, Faculdade de Farmácia, Senior assessor in the Essential Medicines Prequalification Project (WHO-Quality Assurance & Safety: Medicines - Medicines Policy and Standards) no(a) World Health Organization Regional Office for Europe, Perito do Grupo de Avaliação de Produtos Fitofarmacêuticos e do Grupo de Avaliação de Medicamentos Veterinários na Direcção-Geral de Alimentação e Veterinária, Membro do Conselho Científico da Sociedade Portuguesa de Metrologia. Publicou 37 artigos em revistas especializadas. Possui 1 livro(s). Recebeu 9 prémio(s) e/ou homenagens. Nas suas actividades profissionais interagiu com 131 colaborador(es) em co-autorias de trabalhos científicos. No seu currículo Ciência Vitae os termos mais frequentes na contextualização da produção científica e tecnológica são: Starch; Nanocapsules; Neutrophil elastase inhibitors; Topical application.
Identificação

Identificação pessoal

Nome completo
LUÍS FILIPE BAPTISTA PLENO DE GOUVEIA

Nomes de citação

  • Gouveia, Luis
  • Luis F. Gouveia
  • Luis Pleno de Gouveia

Identificadores de autor

Ciência ID
4414-CBF2-330A
ORCID iD
0000-0001-5611-0047

Endereços de correio eletrónico

  • lgouveia@ff.ulisboa.pt (Profissional)

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Francês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Inglês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2003/05/10
Concluído
Farmácia (Doutoramento)
Especialização em Especialidade: Tecnologia Farmacêutica
Universidade de Lisboa, Portugal
"Instrumentação e Métodos Dedicados ao Controlo de Qualidade de Medicamentos Recorrendo À Análise em Fluxo" (TESE/DISSERTAÇÃO)
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2013/05/10 - Atual Professor Auxiliar (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
1993/09/01 - Atual Professor Auxiliar (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
1993/09/01 - Atual Assistente (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
1993/09/01 - Atual Assistente Estagiário (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
1990/09/01 - Atual Assistente Convidado (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 - 2017 Professor Auxiliar (Docente Universitário) Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
2003/05/10 - 2013 Professor Auxiliar (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2017/01/01 - Atual Perito do Grupo de Avaliação de Produtos Fitofarmacêuticos Direcção-Geral de Alimentação e Veterinária, Portugal
2011/01/01 - Atual Senior assessor in the Essential Medicines Prequalification Project (WHO-Quality Assurance & Safety: Medicines - Medicines Policy and Standards) World Health Organization Regional Office for Europe, Dinamarca
2010/03/18 - Atual Perito do Grupo de Avaliação de Medicamentos Veterinários Direcção-Geral de Alimentação e Veterinária, Portugal
2010/01/01 - Atual Membro do Conselho Científico da Sociedade Portuguesa de Metrologia Sociedade Portuguesa de Metrologia, Portugal
1990/09/01 - Atual Bolseiro de Doutoramento da JNICT Fundação para a Ciência e a Tecnologia, Portugal
2005/01/01 - 2010/01/01 Membro do Conselho Directivo da FFUL Universidade de Lisboa Faculdade de Farmácia, Portugal
Projetos

Bolsa

Designação Financiadores
2010 - Atual Aplication of QSAR e PBPK models to predict drugs PK behaviour
FCT-SFRH/BDP/69748/2010
Ministério da Educação
Produções

Publicações

Artigo em conferência
  1. Ribeiro, H.; Marto, J.; Ascenso, A.; Manteigas, P.; Eleuterio, C.V.; Gouveia, L.; Loreau, S.R.; Oliveira, E.; Almeida, A.. "Design of a novel melatonin Pickering emulsion sunscreen". 2015.
Artigo em revista
  1. Gouveia, Luis. "Astaxanthin Extraction from Marine Crustacean Waste Streams: An Integrate Approach between Microwaves and Supercritical Fluids". ACS Sustainable Chemistry & Engineering 9 8 (2021): 3050-3059. https://doi.org/10.1021/acssuschemeng.0c06534.
    10.1021/acssuschemeng.0c06534
  2. Gouveia, Luis. "Supercritical CO2 extraction of bioactive lipids from canned sardine waste streams". Journal of CO2 Utilization 43 (2021): 101359-101359. https://www.sciencedirect.com/science/article/pii/S2212982020309896.
    https://doi.org/10.1016/j.jcou.2020.101359
  3. Carolina Sousa; Luís F. Gouveia; Bruna Kreutzer; Beatriz Silva-Lima; Retsepile E. Maphasa; Admire Dube; Mafalda Videira. "Polymeric Micellar Formulation Enhances Antimicrobial and Anticancer Properties of Salinomycin". Pharmaceutical Research 36 6 (2019): https://doi.org/10.1007%2Fs11095-019-2615-6.
    10.1007/s11095-019-2615-6
  4. Joana Marto; A. Duarte; Sandra Simões; Lídia Gonçalves; Luis Gouveia; António José Almeida; Helena Ribeiro. "Starch-Based Pickering Emulsions as Platforms for Topical Antibiotic Delivery: In Vitro and In Vivo Studies". Polymers (2019): http://www.mdpi.com/2073-4360/11/1/108.
    10.3390/polym11010108
  5. Gouveia, Luis. "Antigenic response to CT-P13 and infliximab originator in inflammatory bowel disease patients shows similar epitope recognition". Alimentary Pharmacology & Therapeutics 0 0 (2018): https://onlinelibrary.wiley.com/doi/abs/10.1111/apt.14808.
    10.1111/apt.14808
  6. J. M. Marto; L. F. Gouveia; L. M. D. Gonçalves; H. M. Ribeiro; A. J. Almeida. "Design of minocycline-containing starch nanocapsules for topical delivery". Journal of Microencapsulation (2018): 1-13. https://doi.org/10.1080/02652048.2018.1487472.
    10.1080/02652048.2018.1487472
  7. Tukulula, M.; Gouveia, L.; Paixao, P.; Hayeshi, R.; Naicker, B.; Dube, A.. "Functionalization of PLGA Nanoparticles with 1,3-ß-glucan Enhances the Intracellular Pharmacokinetics of Rifampicin in Macrophages". Pharmaceutical Research 35 6 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85044822251&partnerID=MN8TOARS.
    10.1007/s11095-018-2391-8
  8. Gouveia, Luis. "Starch nanocapsules containing a novel neutrophil elastase inhibitor with improved pharmaceutical performance". European Journal of Pharmaceutics and Biopharmaceutics 127 (2018): 1-11. http://www.sciencedirect.com/science/article/pii/S0939641117313206.
    https://doi.org/10.1016/j.ejpb.2018.01.011
  9. Paixão, P.; Gouveia, L.F.; Silva, N.; Morais, J.A.G.. "Evaluation of dissolution profile similarity – Comparison between the f2, the multivariate statistical distance and the f2bootstrapping methods". European Journal of Pharmaceutics and Biopharmaceutics 112 (2017): 67-74. http://www.scopus.com/inward/record.url?eid=2-s2.0-85000997402&partnerID=MN8TOARS.
    10.1016/j.ejpb.2016.10.026
  10. Cavaco, M.C.; Pereira, C.; Kreutzer, B.; Gouveia, L.F.; Silva-Lima, B.; Brito, A.M.; Videira, M.. "Evading P-glycoprotein mediated-efflux chemoresistance using Solid Lipid Nanoparticles". European Journal of Pharmaceutics and Biopharmaceutics 110 (2017): 76-84. http://www.scopus.com/inward/record.url?eid=2-s2.0-84995901373&partnerID=MN8TOARS.
    10.1016/j.ejpb.2016.10.024
  11. J. Marto; L.F. Gouveia; B.G. Chiari; A. Paiva; V. Isaac; P. Pinto; P. Simões; A.J. Almeida; H.M. Ribeiro. "The green generation of sunscreens: Using coffee industrial sub-products". Industrial Crops and Products 80 (2016): 93-100. http://dx.doi.org/10.1016/j.indcrop.2015.11.033.
    10.1016/j.indcrop.2015.11.033
  12. Marto, J.; Gouveia, L.F.; Gonçalves, L.; Chiari-Andréo, B.G.; Isaac, V.; Pinto, P.; Oliveira, E.; Almeida, A.J.; Ribeiro, H.M.. "Design of novel starch-based Pickering emulsions as platforms for skin photoprotection". Journal of Photochemistry and Photobiology B: Biology 162 (2016): 56-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-84975862384&partnerID=MN8TOARS.
    10.1016/j.jphotobiol.2016.06.026
  13. Marto, J.; Gouveia, L.F.; Gonçalves, L.M.; Gaspar, D.P.; Pinto, P.; Carvalho, F.A.; Oliveira, E.; Ribeiro, H.M.; Almeida, A.J.. "A Quality by design (QbD) approach on starch-based nanocapsules: A promising platform for topical drug delivery". Colloids and Surfaces B: Biointerfaces 143 (2016): 177-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961140156&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2016.03.039
  14. Marto, J.; Ascenso, A.; Gonçalves, L.M.; Gouveia, L.F.; Manteigas, P.; Pinto, P.; Oliveira, E.; Almeida, A.J.; Ribeiro, H.M.. "Melatonin-based pickering emulsion for skin’s photoprotection". Drug Delivery 23 5 (2016): 1594-1607. http://www.scopus.com/inward/record.url?eid=2-s2.0-84954232162&partnerID=MN8TOARS.
    10.3109/10717544.2015.1128496
  15. Arranja, A.; Gouveia, L.F.; Gener, P.; Rafael, D.F.; Pereira, C.; Schwartz, S.; Videira, M.A.. "Self-assembly PEGylation assists SLN-paclitaxel delivery inducing cancer cell apoptosis upon internalization". International Journal of Pharmaceutics 501 1-2 (2016): 180-189. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961612946&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2016.01.075
  16. Marto, J.; Baltazar, D.; Duarte, A.; Fernandes, A.; Gouveia, L.; Militão, M.; Salgado, A.; et al. "Topical gels of etofenamate: in vitro and in vivo evaluation". Pharmaceutical Development and Technology 20 6 (2015): 710-715. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964238161&partnerID=MN8TOARS.
    10.3109/10837450.2014.915571
  17. Gener, P.; Gouveia, L.P.; Sabat, G.R.; de Sousa Rafael, D.F.; Fort, N.B.; Arranja, A.; Fernández, Y.; et al. "Fluorescent CSC models evidence that targeted nanomedicines improve treatment sensitivity of breast and colon cancer stem cells". Nanomedicine: Nanotechnology, Biology, and Medicine 11 8 (2015): 1883-1892. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951153297&partnerID=MN8TOARS.
    10.1016/j.nano.2015.07.009
  18. Marto, J.; Gouveia, L.; Jorge, I.M.; Duarte, A.; Gonçalves, L.M.; Silva, S.M.C.; Antunes, F.; et al. "Starch-based Pickering emulsions for topical drug delivery: A QbD approach". Colloids and Surfaces B: Biointerfaces 135 (2015): 183-192. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938786377&partnerID=MN8TOARS.
    10.1016/j.colsurfb.2015.07.024
  19. Paixao, P; Aniceto, N; Gouveia, LF; Morais, JAG. "Prediction of Drug Distribution in Rat and Humans Using an Artificial Neural Networks Ensemble and a PBPK Model". Pharmaceutical Research 31 12 (2014): 3313-3322.
    10.1007/s11095-014-1421-4
  20. Paixão, P.; Aniceto, N.; Gouveia, L.F.; Morais, J.A.G.. "Tissue-to-blood distribution coefficients in the rat: Utility for estimation of the volume of distribution in man". European Journal of Pharmaceutical Sciences 50 3-4 (2013): 526-543. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883721885&partnerID=MN8TOARS.
    10.1016/j.ejps.2013.08.020
  21. Videira, M.A.; Arranja, A.G.; Gouveia, L.F.. "Experimental design towards an optimal lipid nanosystem: A new opportunity for paclitaxel-based therapeutics". European Journal of Pharmaceutical Sciences 49 2 (2013): 302-310. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877054295&partnerID=MN8TOARS.
    10.1016/j.ejps.2013.03.005
  22. Paixão, P.; Gouveia, L.F.; Morais, J.A.G.. "An alternative single dose parameter to avoid the need for steady-state studies on oral extended-release drug products". European Journal of Pharmaceutics and Biopharmaceutics 80 2 (2012): 410-417. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856613688&partnerID=MN8TOARS.
    10.1016/j.ejpb.2011.11.001
  23. Paixão, P.; Gouveia, L.F.; Morais, J.A.G.. "Prediction of the human oral bioavailability by using in vitro and in silico drug related parameters in a physiologically based absorption model". International Journal of Pharmaceutics 429 1-2 (2012): 84-98. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859561563&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2012.03.019
  24. Paixão, P.; Gouveia, L.F.; Morais, J.A.G.. "Prediction of the in vitro permeability determined in Caco-2 cells by using artificial neural networks". European Journal of Pharmaceutical Sciences 41 1 (2010): 107-117. http://www.scopus.com/inward/record.url?eid=2-s2.0-77954761477&partnerID=MN8TOARS.
    10.1016/j.ejps.2010.05.014
  25. Mulchande, J.; Oliveira, R.; Carrasco, M.; Gouveia, L.; Guedes, R.C.; Iley, J.; Moreira, R.. "4-Oxo-ß-lactams (azetidine-2,4-diones) are potent and selective inhibitors of human leukocyte elastase". Journal of Medicinal Chemistry 53 1 (2010): 241-253. http://www.scopus.com/inward/record.url?eid=2-s2.0-74849100941&partnerID=MN8TOARS.
    10.1021/jm901082k
  26. Paixão, P.; Gouveia, L.F.; Morais, J.A.G.. "Prediction of the in vitro intrinsic clearance determined in suspensions of human hepatocytes by using artificial neural networks". European Journal of Pharmaceutical Sciences 39 5 (2010): 310-321. http://www.scopus.com/inward/record.url?eid=2-s2.0-77549088567&partnerID=MN8TOARS.
    10.1016/j.ejps.2009.12.007
  27. Santos, C.R.; Capela, R.; Pereira, C.S.G.P.; Valente, E.; Gouveia, L.; Pannecouque, C.; De Clercq, E.; Moreira, R.; Gomes, P.. "Structure-activity relationships for dipeptide prodrugs of acyclovir: Implications for prodrug design". European Journal of Medicinal Chemistry 44 6 (2009): 2339-2346. http://www.scopus.com/inward/record.url?eid=2-s2.0-64249094656&partnerID=MN8TOARS.
    10.1016/j.ejmech.2008.08.009
  28. Cordovil, R.; Araújo, D.; Davids, K.; Gouveia, L.; Barreiros, J.; Fernandes, O.; Serpa, S.. "The influence of instructions and body-scaling as constraints on decision-making processes in team sports". European Journal of Sport Science 9 3 (2009): 169-179. http://www.scopus.com/inward/record.url?eid=2-s2.0-67651046199&partnerID=MN8TOARS.
    10.1080/17461390902763417
  29. Passos, P.; Araújo, D.; Davids, K.; Gouveia, L.; Serpa, S.; Milho, J.; Fonseca, S.. "Interpersonal pattern dynamics and adaptive behavior in multiagent neurobiological systems: Conceptual model and data". Journal of Motor Behavior 41 5 (2009): 445-459. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350754613&partnerID=MN8TOARS.
    10.3200/35-08-061
  30. Paixão, P.; Gouveia, L.F.; Morais, J.A.G.. "Prediction of drug distribution within blood". European Journal of Pharmaceutical Sciences 36 4-5 (2009): 544-554. http://www.scopus.com/inward/record.url?eid=2-s2.0-59349098520&partnerID=MN8TOARS.
    10.1016/j.ejps.2008.12.011
  31. Passos, P.; Araújo, D.; Davids, K.; Milho, J.; Gouveia, L.. "Power law distributions in pattern dynamics of attacker-defender dyads in the team sport of rugby union: Phenomena in a region of self-organized criticality?". E:CO Emergence: Complexity and Organization 11 2 (2009): 37-45. http://www.scopus.com/inward/record.url?eid=2-s2.0-70349808971&partnerID=MN8TOARS.
  32. Santos, C.; Morais, J.; Gouveia, L.; De Clercq, E.; Pannecouque, C.; Nielsen, C.U.; Steffansen, B.; Moreira, R.; Gomes, P.. "Dipeptide derivatives of AZT: Synthesis, chemical stability, activation in human plasma, hPEPT1 affinity, and antiviral activity". ChemMedChem 3 6 (2008): 970-978. http://www.scopus.com/inward/record.url?eid=2-s2.0-48149103948&partnerID=MN8TOARS.
    10.1002/cmdc.200800012
  33. Passos, P.; Araújo, D.; Davids, K.; Gouveia, L.; Milho, J.; Serpa, S.. "Information-governing dynamics of attacker-defender interactions in youth rugby union". Journal of Sports Sciences 26 13 (2008): 1421-1429. http://www.scopus.com/inward/record.url?eid=2-s2.0-55849150190&partnerID=MN8TOARS.
    10.1080/02640410802208986
  34. Chambel, P.; Capela, R.; Lopes, F.; Iley, J.; Morais, J.; Gouveia, L.; Gomes, J.R.B.; Gomes, P.; Moreira, R.. "Reactivity of imidazolidin-4-one derivatives of primaquine: implications for prodrug design". Tetrahedron 62 42 (2006): 9883-9891. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748140661&partnerID=MN8TOARS.
    10.1016/j.tet.2006.08.026
  35. Passos, P.; Araújo, D.; Davids, K.; Gouveia, L.; Serpa, S.. "Interpersonal dynamics in sport: The role of artificial neural networks and 3-D analysis". Behavior Research Methods 38 4 (2006): 683-691. http://www.scopus.com/inward/record.url?eid=2-s2.0-34147197222&partnerID=MN8TOARS.
    10.3758/BF03193901
  36. Videira, M.A.; Botelho, M.F.; Santos, A.C.; Gouveia, L.F.; Pedroso De Lima, J.J.; Almeida, A.J.. "Lymphatic uptake of pulmonary delivered radiolabelled solid lipid nanoparticles". Journal of Drug Targeting 10 8 (2002): 607-613. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036968375&partnerID=MN8TOARS.
    10.1080/1061186021000054933
  37. Cerdeira, A.M.; Gouveia, L.F.; Goucha, P.; Almeida, A.J.. "Drug particle size influence on enteric beads produced by a droplet extrusion/precipitation method". Journal of Microencapsulation 17 6 (2000): 733-741. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033777228&partnerID=MN8TOARS.
  38. Gouveia, L.F.; Costa Lima, J.L.F.; Morais, J.A.G.. "Automated flow-injection system for extending the linear range". Analytica Chimica Acta 366 1-3 (1998): 271-279. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032547087&partnerID=MN8TOARS.
    10.1016/S0003-2670(98)00114-7
  39. Korn, M.; Gouveia, L.F.B.P.; de Oliveira, E.; Reis, B.F.. "Binary search in flow titration employing photometric end-point detection". Analytica Chimica Acta 313 3 (1995): 177-184. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029029847&partnerID=MN8TOARS.
    10.1016/0003-2670(95)00245-U
Livro
  1. Paixão, P.; Gouveia, L.; Guimarães Morais, J.A.; Silva, N.. Correlation between cell- and tissue-based in vitro models for drug permeability screening with in vivo situation: Modeling and functional extrapolation. Modeling and functional extrapolation.. 2015.
    10.1016/B978-0-08-100094-6.00020-1
Distinções

Outra distinção

2015 Best poster communication "Development and optimization of a granulation phase using fluid bed technology and a QbD approach"
2015 Best poster communication - Joana Marto et al, Starch-based nanocapsules as potential carriers for topical delivery
2015 Best poster "Novel melatonin-based pickering emulsion sunscreen"; J.Marto et al
2015 Best poster - Marto J. et al, "Novel melatonin-based pickering emulsion sunsreen"
2014 Award 1st Place – post-graduation session, "Design of a novel melatonin Pickering emulsion sunscreen” II International Symposium on Cosmetology
2013 1st Prize - Poster Nano-Toxicology
2013 Award 1st Place oral presentations, FIP Industrial Pharmacy Section: Microparticles for pulmonar delivery of Fluticasone Propionate: Multifactorial assessment of process and formula variables
2012 Outstanding Manuscript Award in Modeling and Simulation
American Association of Pharmaceutical Scientists, Estados Unidos
2006 “DIA Award - Student Poster Competition” Y. Krim, L.Gouveia, B.Refouvelet