Lígia Silva holds a degree in Pharmaceutical Sciences (October 2006) and a PhD in Pharmaceutical Technology (October 2012) from the University of Coimbra (UC). Her doctoral research, conducted at the Center of Neurosciences and Cell Biology of Coimbra, was focused on developing lipid nanoparticles for the targeted delivery of therapeutic molecules to solid tumors. Following her PhD, Lígia Silva conducted post-doctoral activities at CQC-Coimbra Chemistry Centre (2012-2014, Coimbra, Portugal) and at Centre de Recherche des Cordeliers and Institute Gustave Roussy (2015-2018, Paris, France). Her post-doc work was centered on preclinical investigations of the photosensitizer redaporfin and exploring the link between cell death mechanisms and anti-tumor immunity, particularly in the context of Photodynamic Therapy (PDT). In 2019, Lígia Silva secured a Researcher contract under the transitory law, DL/57, at CQC. Since then, she has led the Photobiology Lab, focusing on Photodynamic therapy, drug delivery, anti-tumor immunity, and mechanisms of cell death. Lígia Silva was the principal investigator (PI) in POLYTHEA, a Marie Curie -Innovative Training Network – European Joint Doctorate. Within Polythea, she coordinated the selection of 10 PhD candidates during the MedChemTrain summer school (Portugal, June 2018) and she organized the first POLYTHEA training school - The Fundamentals of Photodynamic Therapy (Portugal, November 2018). She was also PI of an exploratory FCT grant to study the role of lipid oxidation in the anti-tumor immunity mediated by PDT, managing approximately €300,000. In 2022, Lígia Silva received an individual award (5th edition - CEEC) to cover her salary as an assistant researcher, for six years. Throughout her career, Lígia Silva has supervised or co-supervised 4 PhD, 5 MSc, and 7 BSc students. Currently, she co-supervises 2 PhD students, 1 master student, and 3 bachelor students in Medicinal Chemistry. She frequently serves as a jury member for PhD, MSc, and BSc theses and acts as a referee for prestigious journals such as Nature Communications, ACS Applied Materials and Interfaces, ACS Nano, Chemical Reviews, and Oncoimmunology. Additionally, she evaluates proposals for funding agencies in Belgium and Poland. Lígia Silva and her collaborators regularly participate in international conferences, with 16 appearances since 2019, earning recognition including 2 best poster awards and 1 best oral communication in 2021. Overall, Lígia Silva is an author or co-author of 36 international peer-reviewed publications, including in high-impact journals like JACS, Acc Chem Res, EMBO, Cell Death Differentiation, BBA-Reviews on cancer, Cell Death Disease, Biomaterials, and Oncoimmunology, as well as 5 book chapters. According to Google Scholar, her h-index is 21 with a total of 2232 citations. Lastly, she lectures at the Department of Chemistry of Coimbra, teaching courses such as Labs of Drug Development I, Labs of Chemistry II, and tutorials of Chemistry. She has also been invited to lecture at the MedChemTrain and POLYTHEA PhD programs.

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Lígia Catarina Gomes da Silva

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