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Rafaela Costa (RC) holds a B.Sc. (2019) and an M.Sc. degree (2021) in Biochemistry, which were granted by the Faculty of Sciences of the University of Porto and concluded with the final grades of 17 and 18 (out of 20), respectively. During the B.Sc. degree, RC undertook a curricular internship in the field of Ecotoxicology, focusing on the biological impact of nanoplastics and lithium on the freshwater bivalve Corbicula fluminea. This study allowed for the first contact of RC with research on aquatic organisms and was presented at an international congress, with an extended abstract published in book format. During the M.Sc., RC developed her dissertation on the topic "a-Ketoglutarate, amino acid homeostasis and lifespan in a yeast model of Niemann-Pick type C1" (NPC1), with the aim of characterizing the role of a-ketoglutarate and amino acids in the lifespan of a yeast model of NPC1, and in the activation of nutrient-sensing pathways that control cell growth and metabolism (e.g., TORC1 and autophagy). Throughout this period, RC acquired extensive expertise in subcellular fractionation techniques and molecular biology tools, such as PCR, DNA and protein electrophoresis, and Western blotting analyses. The dissertation was classified with 19 (out of 20) and resulted in the publication of a manuscript in the International Journal of Molecular Sciences, a high-impact journal ranked in Q1 in the Biochemistry and Molecular Biology field (doi: 10.3390/ijms24076221). Driven by a deep fascination for nutrition and metabolism, RC started her professional research career at the Interdisciplinary Centre of Marine and Environmental Research (CIIMAR) in April 2022, with a contract under the SIDESTREAM European project, which aims to explore the potential of low trophic organisms, namely polychaetes, as novel sustainable ingredients for aquafeeds. RC has become highly experienced in fish husbandry and tissue sampling, enzymatic activity (e.g., oxidative stress and lipogenesis-related enzymes), lipid peroxidation, and antioxidant capacity analyses, metabolites quantification, and immune parameters evaluation. Additionally, RC has been highly involved in science communication events, participating in the Aquaculture Europe 2022 international congress and the 6th AquaImprove - Aquaculture Research Workshop (oral presentation), among others. Currently, RC is a team member of the INSECTERA project and has a research contract under the INFISHMIX international project, focused on the use of insects in diets for Atlantic salmon and seabass. In 2023, RC was awarded an FCT Ph.D. scholarship, which will allow the continuation of her studies in the field of aquaculture nutrition. The proposed project will provide RC with the opportunity to broaden her understanding of sustainable aquaculture practices and fish nutrition by investigating the impact of new ingredients on fish growth and resilience under the changing climate. RC aims to take a holistic approach to the project and analyze various factors that affect fish health and productivity, ultimately contributing to the development of more efficient and sustainable aquafeeds.
Identificação

Identificação pessoal

Nome completo
Rafaela Silva Costa

Nomes de citação

  • Costa, Rafaela S.
  • Costa, Rafaela
  • Costa, R.S.

Identificadores de autor

Ciência ID
2E1C-1321-EE41
ORCID iD
0000-0002-7196-2616

Endereços de correio eletrónico

  • rcosta@ciimar.up.pt (Profissional)

Moradas

  • ICBAS - Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Porto, Portugal (Profissional)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Bioquímica
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Naturais - Ciências Biológicas - Biologia Marinha

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador elementar (A1) Utilizador elementar (A2) Utilizador elementar (A1) Utilizador elementar (A2)
Formação
Grau Classificação
2019 - 2021
Concluído
Bioquímica (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
"a-Ketoglutarate, amino acid homeostasis and lifespan in a yeast model of Niemann-Pick type C1" (TESE/DISSERTAÇÃO)
18 (Dissertation classification: 19)
2016 - 2019
Concluído
Bioquímica (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Effects of nanoplastics and lithium, alone and in combination, on the freshwater bivalve Corbicula fluminea" (TESE/DISSERTAÇÃO)
17 (Report classification: 19)
2013 - 2016
Concluído
Ciências e Tecnologias (Ensino secundário)
Escola Secundária D. Afonso Sanches, Portugal
18
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2023/02/21 - 2023/10 Investigador (Investigação) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2022/04/21 - 2023/02/20 Investigador (Investigação) Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
2020/09 - 2021/12 Estagiário de Investigação (Investigação) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/02 - 2019/09 Estagiário de Investigação (Investigação) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Projetos

Projeto

Designação Financiadores
2023/02/21 - 2023/10 INFISHMIX - Combining insects for a novel circular strategy towards fish growth and robustness
MOD.PN.DOC.065.EN.V01
Investigador
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Em curso
2022/04/21 - 2023/02/20 SIDESTREAM - Secondary bio-production of low-trophic organisms utilizing side streams from the Blue and Green sectors to produce novel feed ingredients for European aquaculture
BLUEBIO/0005/2019
Investigador
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Concluído

Outro

Designação Financiadores
2023/03 - Atual InsectERA - A ERA da indústria dos insetos
C644917393-00000032
Team member
Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal
Em curso
Produções

Publicações

Artigo em revista
  1. Monteiro, M.; Marques, A.; Costa, Rafaela S.; Salgado, M.A.; Castro, C.; Conceição, L.; Valente, L.M.P.. "Beyond fish oil: Assessing the implications of alternative dietary lipid sources for turbot (Scophthalmus maximus) on growth, nutrient utilization and muscle quality". Aquaculture (2023): 740073. http://dx.doi.org/10.1016/j.aquaculture.2023.740073.
    Publicado • 10.1016/j.aquaculture.2023.740073
  2. T. S. Martins; R.S. Costa; R. Vilaça; C. Lemos; V. Teixeira; C. Pereira; V. Costa. "Iron Limitation Restores Autophagy and Increases Lifespan in the Yeast Model of Niemann-Pick Type C1". International Journal of Molecular Sciences (2023): https://www.mdpi.com/1422-0067/24/7/6221.
    10.3390/ijms24076221
Poster em conferência
  1. Martins, Telma S.; Costa, Rafaela S.; Lemos, Carolina; Pereira, Clara; Costa, Vítor. "Vacuolar membrane proteome and role of amino acids in the lifespan of a Niemann-Pick type C1 yeast model". Trabalho apresentado em XXI SPB National Congress of Biochemistry, 14-16 October 2021, Évora, 2021.
  2. Martins, Telma S.; Costa, Rafaela; Lemos, Carolina; Pereira, Clara; Costa, Vítor. "Regulation of the lysosome-like vacuole and amino acid homeostasis in the yeast model of Niemann-Pick type C1". Trabalho apresentado em 45th FEBS Congress, 3-8 July 2021, 2021.
Resumo em conferência
  1. Costa, Rafaela S.; Monteiro, M.; Thoresen, L.; Kousoulaki, K.; Valente, L.M.P.. "Dietary replacement of fishmeal with polychaete meal (Alitta virens) impacts European seabass acute stress response". Trabalho apresentado em II TOXRUN International Congress, Porto, 2023.
  2. Costa, Rafaela S.; Monteiro, M.; Silva, J.; Kousoulaki, K.; Thoresen, L.; Valente, L.M.P.. "Feeding the future: The potential of polychaete meal for European seabass functional diets". Trabalho apresentado em Aquaculture Europe 2023, Vienna, 2023.
    Aceite para publicação
  3. Costa, Rafaela S.; Monteiro, M.; Sá, T.; Kousoulaki, K.; Thoresen, L.; Valente, L.M.P.. "Dietary replacement of fish meal by polychaete meal (Alitta virens): effects on European seabass growth performance and metabolism". Trabalho apresentado em 6th AquaImprove – Aquaculture Research Workshop, 19 October 2022, Matosinhos, 2022.
    Publicado
  4. Monteiro, M.; Costa, Rafaela S.; Sá, T.; Kousoulaki, K.; Thoresen L.; Valente, L.M.P.. "Exploring the potential of low trophic species Alitta virens to replace fish meal in diets for European sea bass". Trabalho apresentado em Aquaculture Europe 2022, 28-30 September 2022, Rimini, 2022.
    Publicado
  5. Costa, Rafaela S.; Oliveira, Patrícia; Guilhermino, L.. "Effects of Nanoplastics, Lithium, and Their Mixtures on Corbicula fluminea: Preliminary Findings". Trabalho apresentado em Geoethics & Groundwater Management Congress, 18-22 May 2020, Porto, 2021.
    Publicado • 10.1007/978-3-030-59320-9_57
  6. Costa, Rafaela S.; Martins, Telma S.; Pereira, Clara; Costa, Vítor. "Role of Gln3 and amino acids in the yeast model of Niemann-Pick type C1". Trabalho apresentado em IJUP’21 – 14th Meeting of Young Researchers of University of Porto, 5-7 May 2021, Porto, 2021.
    Publicado
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/09/19 Feeding the future: The potential of polychaete meal for European seabass functional diets Aquaculture Europe 2023
(Vienna, Áustria)
2023/04/27 Dietary replacement of fishmeal with polychaete meal (Alitta virens) impacts European seabass acute stress response II TOXRUN International Congress
(Porto, Portugal)
2022/10/19 Dietary replacement of fish meal by polychaete meal (Alitta virens): Effects on European seabass growth performance and metabolism 6th AquaImprove – Aquaculture Research Workshop
(Matosinhos, Portugal)
2021/05 Role of Gln3 and amino acids in the yeast model of Niemann-Pick type C1 IJUP’2021 – 14th Meeting of Young Researchers of University of Porto
University of Porto (Portugal)
2020/05 Effects of Nanoplastics, Lithium and Their Mixtures on Corbicula fluminea: Preliminary Findings 1st Congress on Geoethics and Groundwater Management (GEOETH&GWM'20)
(Porto, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2022/09 - 2023/07 Organismos de baixo nível trófico como novos ingredientes para aquacultura
Coorientador
Biology (Licenciatura/Bacharelato)
Universidade do Porto Faculdade de Ciências, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2023/06/05 - 2023/06/09 Attendance of the Advanced Course in Fish Nutrition, Feeding and Health (32 hours), jointly organized by CIHEAM Zaragoza and the NewTechAqua project Advanced Course in Fish Nutrition, Feeding and Health
Mediterranean Agronomic Institute of Zaragoza (CIHEAM Zaragoza), Espanha
2022/09/27 - 2022/09/30 International annual conference on aquaculture topics
Conferência
Aquaculture Europe 2022, 28-30 September 2022, Rimini
European Aquaculture Society, Bélgica
2022/09/15 - 2022/09/15 Workshop on the topic "Global Changes and Animal Nutrition"
Oficina (workshop)
Workshop of the Animal Science Doctoral Programme - 2022
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/03/22 - 2022/03/22 Lectures on the topics "Fish parasites - Bad and not so bad guys" and "How do RNA viruses evolve? An example of the rabbit hemorrhagic disease", by Aurélia Saraiva and Joana Abrantes, respectively
Seminário
Biologia ao Fim da Tarde
Universidade do Porto Faculdade de Ciências, Portugal
2022/03/08 - 2022/03/08 Lectures on the topics "Zebrafish: a new experimental model" and "Sustainable aquaculture", by António Paulo Carvalho and Aires Oliva Teles
Seminário
Biologia ao Fim da Tarde
Universidade do Porto Faculdade de Ciências, Portugal