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Rui Pinto is a Professor of Pharmacology at the Department of Pharmacy, Pharmacology and Health Technologies of the Faculty of Pharmacy – University of Lisbon. He is Pharmacist Specialist in clinical analysis (AC) and in human genetics (GH) by the Order of Pharmacists (OF). With the background in Pharmacology and Laboratory Medicine, he is interested in the research areas related to the identification and validation of biomarkers associated with the pathophysiology of diseases using animal models. His background in the area related to the drug-receptor interaction has allowed him to develop experimental work in the field of molecular pharmacology and inflammation. He leads a line of research that he began to develop in 2011 related to the pharmacological modulation of inflammation associated with inflammatory bowel disease – from animal model study to clinical trial. The research areas in which he is involved already allow the publication of more than 110 full papers in international peer-reviewed journals with a total number of citations (web of science): 1393 and acts as reviewer of international peer-reviewed journals in the area of Pharmacology and Laboratory Medicine. In the Health Regulatory area, he is a Pre-Clinical Pharmacology and Toxicology Expert Assessor for the Medicines Evaluation Committee at INFARMED (National Authority of Medicines and Health Products). He is also a Toxicological and Pharmaceutical Expert Assessor for DGAV (Directorate General for Food and Veterinary). He is Chairman of the Board of the College of Specialties in AC and GH of the OF (2016-2021); Member of the Board of the Order of Pharmacists and founding partner of the European Union of Pharmacists Specialists in AC and GH (EUPLMG).
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Identificação

Identificação pessoal

Nome completo
Rui Manuel Amaro Pinto

Nomes de citação

  • Pinto, Rui

Identificadores de autor

Ciência ID
2B10-96CF-BFC4
ORCID iD
0000-0002-1667-7871

Endereços de correio eletrónico

  • rapinto@ff.ulisboa.pt (Profissional)
Formação
Grau Classificação
2006/11/17
Concluído
 Farmácia (Doutoramento)
Especialização em Especialidade: Farmacologia
Universidade de Lisboa, Portugal
"Papel do Monóxido de Azoto no Aparelho Reprodutor Masculino: Estudos em Canal Deferente de Rato e em Espermatozóides Humanos" (TESE/DISSERTAÇÃO)
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2006/11/17 - Atual Professor Auxiliar (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal
2016/11/17 - 2018 Professor Auxiliar (Docente Universitário) Universidade de Lisboa, Portugal
2013/11/17 - 2016 Professor Auxiliar (Docente Universitário) Universidade de Lisboa Faculdade de Farmácia, Portugal

Cargos e Funções

Categoria Profissional
Instituição de acolhimento 		Empregador
2000/01/03 - Atual Especialista em Análises Clínicas e Genética Humana Joaquim Chaves Saúde, Portugal
Joaquim Chaves Saúde, Portugal
Projetos

Bolsa

Designação Financiadores
2015 - Atual IBD Inflammatory Bowel Disease
SIFIDE/2015/JCS
 Jefferson Central School
Produções

Publicações

Artigo em revista
  1. Cristina M. Alfaia; Mónica M. Costa; Rui M. A. Pinto; José M. Pestana; Miguel Mourato; Patrícia Carvalho; Cátia F. Martins; et al. "Plasma Metabolites and Liver Composition of Broilers in Response to Dietary Ulva lactuca with Ulvan Lyase or a Commercial Enzyme Mixture". Molecules (2022): https://doi.org/10.3390/molecules27217425.
    10.3390/molecules27217425
  2. Inês Silva; João Solas; Rui Pinto; Vanessa Mateus. "Chronic Experimental Model of TNBS-Induced Colitis to Study Inflammatory Bowel Disease". International Journal of Molecular Sciences 23 9 (2022): 4739-4739. https://doi.org/10.3390/ijms23094739.
    10.3390/ijms23094739
  3. Silva, I.; Mendes, P.; Guerra, S.; Pinto, R.; Mateus, V.. "Anti-Inflammatory Effect of Topiramate in a Chronic Model of TNBS-Induced Colitis". International Journal of Molecular Sciences 23 16 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85136700698&partnerID=MN8TOARS.
    10.3390/ijms23169127
  4. Silva, I.; Correia, R.; Pinto, R.; Mateus, V.. "Hemin Ameliorates the Inflammatory Activity in the Inflammatory Bowel Disease: A Non-Clinical Study in Rodents". Biomedicines 10 8 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85137339206&partnerID=MN8TOARS.
    10.3390/biomedicines10082025
  5. Modesto, R.; Estarreja, J.; Silva, I.; Rocha, J.; Pinto, R.; Mateus, V.. "Chemically Induced Colitis-Associated Cancer Models in Rodents for Pharmacological Modulation: A Systematic Review". Journal of Clinical Medicine 11 10 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85129813597&partnerID=MN8TOARS.
    10.3390/jcm11102739
  6. Mateus, V.; Estarreja, J.; Silva, I.; Gonçalves, F.; Teixeira-Lemos, E.; Pinto, R.. "Effect of Aqueous Extract of Phenolic Compounds Obtained from Red Wine in Experimental Model of Colitis in Mice". Current Issues in Molecular Biology 44 6 (2022): 2745-2758. http://www.scopus.com/inward/record.url?eid=2-s2.0-85132606318&partnerID=MN8TOARS.
    10.3390/cimb44060188
  7. Costa, M.M.; Lopes, P.A.; Assunção, J.M.P.; Alfaia, C.M.R.P.M.; Coelho, D.F.M.; Mourato, M.P.; Pinto, R.M.A.; Lordelo, M.M.; Prates, J.A.M.. "Combined effects of dietary Laminaria digitata with alginate lyase on plasma metabolites and hepatic lipid, pigment and mineral composition of broilers". BMC Veterinary Research 18 1 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85128968503&partnerID=MN8TOARS.
    10.1186/s12917-022-03250-3
  8. Martins, C.F.; Lopes, P.A.; Palma, M.; Pinto, R.M.A.; Costa, M.; Alfaia, C.M.; Pestana, J.M.; et al. "Impact of dietary Chlorella vulgaris and feed enzymes on health status, immune response and liver metabolites in weaned piglets". Scientific reports 12 1 (2022): 16816-16816. http://www.scopus.com/inward/record.url?eid=2-s2.0-85139571216&partnerID=MN8TOARS.
    10.1038/s41598-022-21238-9
  9. Coelho, D.; Alfaia, C.M.; Lopes, P.A.; Pestana, J.M.; Costa, M.M.; Pinto, R.M.A.; Almeida, J.M.; et al. "Impact of Chlorella vulgaris as feed ingredient and carbohydrases on the health status and hepatic lipid metabolism of finishing pigs". Research in Veterinary Science 144 (2022): 44-53. http://www.scopus.com/inward/record.url?eid=2-s2.0-85123016529&partnerID=MN8TOARS.
    10.1016/j.rvsc.2022.01.008
  10. Kydonaki, E.K.; Freitas, L.; Reguengo, H.; Simón, C.R.; Bastos, A.R.; Fernandes, E.M.; Canadas, R.F.; et al. "Pharmacological and Non-Pharmacological Agents versus Bovine Colostrum Supplementation for the Management of Bone Health Using an Osteoporosis-Induced Rat Model". Nutrients 14 14 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85135105352&partnerID=MN8TOARS.
    10.3390/nu14142837
  11. Eirini Kalliopi Kydonaki; Laura Freitas; Bruno M Fonseca; HENRIQUE REGUENGO; Carlos; Ana R. Bastos; Emanuel M. Fernandes; et al. "Bovine Colostrum Supplementation Improves Bone Metabolism in an Osteoporosis-Induced Animal Model". Nutrients (2021): https://www.mdpi.com/2072-6643/13/9/2981.
    10.3390/nu13092981
  12. Vanessa Mateus; João Estarreja; Inês Silva; Paulo Barracosa; Edite Teixeira-Lemos; Rui Pinto. "Effect of Cynara cardunculus L. var. altilis (DC) in Inflammatory Bowel Disease". Applied Sciences 11 4 (2021): 1629-1629. https://doi.org/10.3390/app11041629.
    10.3390/app11041629
  13. Inês Vieira da Silva; Miriam Echevarría; Bárbara P. Soares; Catarina Pimpão; Rui M. A. Pinto; Teresa Costa; João P. B. Freire; et al. "Glutamine and cystine-enriched diets modulate aquaporins gene expression in the small intestine of piglets". PLOS ONE 16 1 (2021): e0245739-e0245739. https://doi.org/10.1371/journal.pone.0245739.
    10.1371/journal.pone.0245739
  14. dos Santos Madeira, M.S.M.; Lopes, P.A.A.B.; Martins, C.F.; Assunção, J.M.P.; Alfaia, C.M.R.P.M.; Pinto, R.M.A.; Prates, J.A.M.. "Dietary Arthrospira platensis improves systemic antioxidant potential and changes plasma lipids without affecting related hepatic metabolic pathways in post-weaned piglets". BMC Veterinary Research 17 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85104285125&partnerID=MN8TOARS.
    10.1186/s12917-021-02869-y
  15. Bártolo, I.; Santos, B.S.; Fontinha, D.; MacHado, M.; Francisco, D.; Sepodes, B.; Rocha, J.; et al. "Spiro-ß-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium". ACS Infectious Diseases 7 2 (2021): 421-434. http://www.scopus.com/inward/record.url?eid=2-s2.0-85099655355&partnerID=MN8TOARS.
    10.1021/acsinfecdis.0c00768
  16. Prates, J.A.M.; Freire, J.P.B.; de Almeida, A.M.; Martins, C.; Ribeiro, D.M.; Osório, H.; Pinho, M.A.S.; et al. "Influence of dietary supplementation with an amino acid mixture on inflammatory markers, immune status and serum proteome in lps-challenged weaned piglets". Animals 11 4 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85104319060&partnerID=MN8TOARS.
    10.3390/ani11041143
  17. Coelho, D.F.M.; Alfaia, C.M.R.P.M.; Assunção, J.M.P.; Costa, M.; Pinto, R.M.A.; de Andrade Fontes, C.M.G.; Lordelo, M.M.; Prates, J.A.M.. "Impact of dietary Chlorella vulgaris and carbohydrate-active enzymes incorporation on plasma metabolites and liver lipid composition of broilers". BMC Veterinary Research 17 1 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85110200611&partnerID=MN8TOARS.
    10.1186/s12917-021-02932-8
  18. Kislaya, I.; Gonçalves, P.; Barreto, M.; Sousa, R.D.; Garcia, A.C.; Matos, R.; Guiomar, R.; et al. "Seroprevalence of SARS-CoV-2 infection in Portugal in May-July 2020: Results of the first national serological survey (ISNCOVID-19),Seroprevalência da infecção por SARS-CoV-2 em Portugal em Maio-Julho de 2020: Resultados do primeiro inquérito serológico nacional (ISNCOVID-19)". Acta Medica Portuguesa 34 2 (2021): 87-94. http://www.scopus.com/inward/record.url?eid=2-s2.0-85101582944&partnerID=MN8TOARS.
    10.20344/amp.15122
  19. Silva, I.; Alípio, C.; Pinto, R.; Mateus, V.. "Potential anti-inflammatory effect of erythropoietin in non-clinical studies in vivo: A systematic review". Biomedicine and Pharmacotherapy 139 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85104669780&partnerID=MN8TOARS.
    10.1016/j.biopha.2021.111558
  20. Grácio, M.; Rocha, J.; Pinto, R.; Boavida Ferreira, R.; Solas, J.; Eduardo-Figueira, M.; Sepodes, B.; Ribeiro, A.C.. "A proposed lectin-mediated mechanism to explain the in Vivo antihyperglycemic activity of ¿-conglutin from Lupinus albus seeds". Food Science and Nutrition 9 11 (2021): 5980-5996. http://www.scopus.com/inward/record.url?eid=2-s2.0-85115063677&partnerID=MN8TOARS.
    10.1002/fsn3.2520
  21. Mota, A.H.; Duarte, N.; Serra, A.T.; Ferreira, A.; Bronze, M.R.; Custódio, L.; Gaspar, M.M.; et al. "Further evidence of possible therapeutic uses of sambucus nigra l. Extracts by the assessment of the in vitro and in vivo anti-inflammatory properties of its plga and pcl-based nanoformulations". Pharmaceutics 12 12 (2020): 1-28. http://www.scopus.com/inward/record.url?eid=2-s2.0-85097221454&partnerID=MN8TOARS.
    10.3390/pharmaceutics12121181
  22. Amaro-Leal, Â.; Shvachiy, L.; Pinto, R.; Geraldes, V.; Rocha, I.; Mota-Filipe, H.. "Therapeutic effects of IkB kinase inhibitor during systemic inflammation". International Immunopharmacology 84 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85083574926&partnerID=MN8TOARS.
    10.1016/j.intimp.2020.106509
  23. Amaral, M.; Martins, A.S.; Catarino, J.; Faísca, P.; Kumar, P.; Pinto, J.F.; Pinto, R.; et al. "How can biomolecules improve mucoadhesion of oral insulin? A comprehensive insight using ex-vivo, in silico, and in vivo models". Biomolecules 10 5 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85083970308&partnerID=MN8TOARS.
    10.3390/biom10050675
  24. Pestana, J.M.; Puerta, B.; Santos, H.; Madeira, M.S.; Alfaia, C.M.; Lopes, P.A.; Pinto, R.M.A.; et al. "Erratum: Impact of dietary incorporation of Spirulina (Arthrospira platensis) and exogenous enzymes on broiler performance, carcass traits, and meat quality (Poultry Science (2020) 99(5) (2519–2532), (S0032579120300195), (10.1016/j.psj.2019.11.069))". Poultry Science 99 8 (2020): 4100-4100. http://www.scopus.com/inward/record.url?eid=2-s2.0-85088648965&partnerID=MN8TOARS.
    10.1016/j.psj.2020.07.001
  25. Pestana, J.M.; Puerta, B.; Santos, H.; Madeira, M.S.; Alfaia, C.M.; Lopes, P.A.; Pinto, R.M.A.; et al. "Impact of dietary incorporation of Spirulina (Arthrospira platensis) and exogenous enzymes on broiler performance, carcass traits, and meat quality". Poultry Science 99 5 (2020): 2519-2532. http://www.scopus.com/inward/record.url?eid=2-s2.0-85081245935&partnerID=MN8TOARS.
    10.1016/j.psj.2019.11.069
  26. Kydonaki, Eirini; Freitas, Laura; Fonseca, Bruno; Reguengo, Henrique; Simon, Carlos; Bastos, Ana; Canadas, Raphael; et al. "Bovine colostrum improves bone microstructure in ovariectomized and orchidectomy rats via VEGFA signaling". Journal of Bone and Mineral Research (2020): https://publons.com/wos-op/publon/40693326/.
  27. Pinto, Rui. "Preclinical Study in Vivo for New Pharmacological Approaches in Inflammatory Bowel Disease: A Systematic Review of Chronic Model of TNBS-Induced Colitis". Journal of Clinical Medicine (2019): http://dx.doi.org/10.3390/jcm8101574.
    10.3390/jcm8101574
  28. Rosa Direito; João Rocha; Ana-Teresa Serra; Adelaide Fernandes; Marisa Freitas; Eduarda Fernandes; Rui Pinto; et al. "Anti-inflammatory Effects of Persimmon (Diospyros kaki L.) in Experimental Rodent Rheumatoid Arthritis". Journal of Dietary Supplements (2019): https://doi.org/10.1080/19390211.2019.1645256.
    10.1080/19390211.2019.1645256
  29. Rosa Direito; Catarina Reis; Luís Roque; Margarida Gonçalves; Ana Sanches-Silva; Maria Manuela Gaspar; Rui Pinto; et al. "Phytosomes with Persimmon (Diospyros kaki L.) Extract: Preparation and Preliminary Demonstration of In Vivo Tolerability". Pharmaceutics (2019): https://doi.org/10.3390/pharmaceutics11060296.
    10.3390/pharmaceutics11060296
  30. Rosa Direito; João Rocha; Ana Lima; Maria Margarida Gonçalves; Maria Paula Duarte; Vanessa Mateus; Catarina Sousa; et al. "Reduction of Inflammation and Colon Injury by a Spearmint Phenolic Extract in Experimental Bowel Disease in Mice". Medicines 6 2 (2019): 65-65. https://doi.org/10.3390/medicines6020065.
    10.3390/medicines6020065
  31. Rocha, J.; Direito, R.; Lima, A.; Mota, J.; Gonçalves, M.; Duarte, M.P.; Solas, J.; et al. "Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in experimental inflammatory bowel disease in mice". Biomedicine and Pharmacotherapy 118 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85070874907&partnerID=MN8TOARS.
    10.1016/j.biopha.2019.109351
  32. Pinto, R.; Mateus, V.; Centeno, A.; Cardoso, C.; Domingos, C.; Pinto, S.; Pecegueiro, J.. "Role of the medicine laboratory in the development of new therapeutics: A non-clinical study on the use of erythropoietin in a model of inflammatory bowel disease". Clinica Chimica Acta (2019): https://publons.com/wos-op/publon/44177280/.
    10.1016/J.CCA.2019.03.802
  33. Amorim, Tania; Freitas, Laura; Kydonaki, Eirini K.; Reguendo, Henrique; Simon, Carlos R.; Bastos, Ana R.; Canadas, Raphael F.; et al. "Bovine Colostrum Supplementation and Bone Health: a Pilot Study". Journal of Bone and Mineral Research (2019): https://publons.com/wos-op/publon/33091847/.
  34. Vanessa Mateus; João Rocha; Helder Mota-Filipe; Bruno Sepodes; Rui Pinto. "Hemin reduces inflammation associated with TNBS-induced colitis". Clinical and Experimental Gastroenterology (2018): https://doi.org/10.2147/CEG.S166197.
    10.2147/CEG.S166197
  35. Carlos Cardoso; Joana Paiva Martinho; Paula A. Lopes; Susana Martins; Jorge Correia; Cláudia Afonso; Francisco J. Alarcón; et al. "Stearidonic acid combined with alpha-linolenic acid improves lipemic and neurological markers in a rat model subject to a hypercaloric diet". Prostaglandins, Leukotrienes and Essential Fatty Acids 135 (2018): 137-146. https://doi.org/10.1016/j.plefa.2018.07.010.
    10.1016/j.plefa.2018.07.010
  36. Inês Bártolo; Philippe A. Gallay; Ana Rita Diniz; Pedro Borrego; João Pedro Ferreira; Maria Rosário Bronze; Helena Barroso; et al. "Evaluation of the fusion inhibitor P3 peptide as a potential microbicide to prevent HIV transmission in women". PLOS ONE 13 4 (2018): e0195744-e0195744. https://doi.org/10.1371/journal.pone.0195744.
    10.1371/journal.pone.0195744
  37. Aguiar, P.; Azevedo, O.; Pinto, R.; Marino, J.; Cardoso, C.; Sousa, N.; Cunha, D.; Hughes, D.; Soares, J.L.D.. "Biomarkers of myocardial fibrosis: Revealing the natural history of fibrogenesis in Fabry disease cardiomyopathy". Journal of the American Heart Association 7 6 (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85043711679&partnerID=MN8TOARS.
    10.1161/JAHA.117.007124
  38. "Tubular dysfunction biomarkers in Fabry disease: better than albuminuria to identify patients at risk of nephropathy progression". Molecular Genetics and Metabolism (2018): https://publons.com/wos-op/publon/11908988/.
    10.1016/J.YMGME.2017.12.014
  39. "Collagen type I synthesis biomarkers predict the progression of Fabry disease cardiomyopathy". Molecular Genetics and Metabolism (2018): https://publons.com/wos-op/publon/11908989/.
    10.1016/J.YMGME.2017.12.013
  40. Bartolo, Ines; Diniz, Ana Rita; Borrego, Pedro; Ferreira, Joao Pedro; Bronze, Maria Rosario; Barroso, Helena; Pinto, Rui; et al. "Evaluation of the fusion inhibitor P3 peptide as a potential microbicide to prevent HIV transmission in women (vol 13, e0195744, 2018)". Plos One (2018): https://publons.com/wos-op/publon/15571592/.
    10.1371/JOURNAL.PONE.0197015
  41. Madeira, Marta S; Rolo, Eva A; Lopes, Paula A; Ramos, Denis A; Alfaia, Cristina M; Pires, Virginia Mr; Martins, Susana V; Pinto, Rui Ma; Prates, Jose Am. "Betaine and arginine supplementation of low protein diets improves plasma lipids but does not affect hepatic fatty acid composition and related gene expression profiling in pigs.". Journal of the science of food and agriculture (2017): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:28664986&KeyUID=MEDLINE:28664986.
    10.1002/jsfa.8504
  42. Madeira, M.S.M.S.; Rolo, E.S.A.; Pires, V.M.R.; Alfaia, C.M.R.P.M.; Coelho, D.F.M.; Lopes, P.A.A.B.; Martins, S.I.V.; Pinto, R.M.A.; Prates, J.A.M.. "Arginine supplementation modulates pig plasma lipids, but not hepatic fatty acids, depending on dietary protein level with or without leucine". BMC Veterinary Research 13 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85020023702&partnerID=MN8TOARS.
    10.1186/s12917-017-1063-y
  43. Aguiar, Patricio; Azevedo, Olga; Pinto, Rui; Marino, Jacira; Cardoso, Carlos; Ducla Soares, Jose Luis; Hughes, Derralynn. "Increase synthesis of collagen type I: an early event in Fabry cardiomyopathy. New biomarkers?". Molecular Genetics and Metabolism 120 1-2 (2017): S17-S18. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000393734000005&KeyUID=WOS:000393734000005.
    10.1016/j.ymgme.2016.11.012
  44. Direito, R.; Lima, A.; Rocha, J.; Ferreira, R.B.; Mota, J.; Rebelo, P.; Fernandes, A.; et al. "Dyospiros kaki phenolics inhibit colitis and colon cancer cell proliferation, but not gelatinase activities". Journal of Nutritional Biochemistry 46 (2017): 100-108. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018410246&partnerID=MN8TOARS.
    10.1016/j.jnutbio.2017.03.002
  45. Mateus, V.; Rocha, J.; Alves, P.; Mota-Filipe, H.; Sepodes, B.; Pinto, R.. "Thiadiazolidinone-8 Ameliorates Inflammation Associated with Experimental Colitis in Mice". Pharmacology (2017): 35-42. http://www.scopus.com/inward/record.url?eid=2-s2.0-85030680048&partnerID=MN8TOARS.
    10.1159/000471808
  46. Lopes, P.A.; Bandarra, N.M.; Martins, S.V.; Martinho, J.; Alfaia, C.M.; Madeira, M.S.; Cardoso, C.; et al. "Markers of neuroprotection of combined EPA and DHA provided by fish oil are higher than those of EPA (Nannochloropsis) and DHA (Schizochytrium) from microalgae oils in Wistar rats". Nutrition and Metabolism 14 1 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85030184363&partnerID=MN8TOARS.
    10.1186/s12986-017-0218-y
  47. De Mello-Sampayo, C.; Paterna, A.; Polizzi, A.; Duarte, D.; Batista, I.; Pinto, R.; Gonçalves, P.; et al. "Evaluation of marine microalga Diacronema vlkianum biomass fatty acid assimilation in Wistar rats". Molecules 22 7 (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85027837719&partnerID=MN8TOARS.
    10.3390/molecules22071097
  48. Aguiar, P.; Azevedo, O.; Pinto, R.; Marino, J.; Baker, R.; Cardoso, C.; Ducla Soares, J.L.; Hughes, D.. "New biomarkers defining a novel early stage of Fabry nephropathy: A diagnostic test study". Molecular Genetics and Metabolism 121 2 (2017): 162-169. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019596623&partnerID=MN8TOARS.
    10.1016/j.ymgme.2017.05.007
  49. Bandarra, N.M.; Lopes, P.A.; Martins, S.V.; Ferreira, J.; Alfaia, C.M.; Rolo, E.A.; Correia, J.J.; et al. "Docosahexaenoic acid at the sn-2 position of structured triacylglycerols improved n-3 polyunsaturated fatty acid assimilation in tissues of hamsters". Nutrition Research 36 5 (2016): 452-463. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961793590&partnerID=MN8TOARS.
    10.1016/j.nutres.2015.12.015
  50. Aguiar, Patricio; Pinto, Rui; Azevedo, Olga; Marino, Jacira; Baker, Rob; Cardoso, Carlos; Ducla Soares, Jose Luis; Hughes, Derralynn. "Urinary type IV collagen: Better than albuminuria to identify incipient Fabry nephropathy". Molecular Genetics and Metabolism 117 2 (2016): S16-S16. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000370888100008&KeyUID=WOS:000370888100008.
    10.1016/j.ymgme.2015.12.165
  51. Madeira, M.S.; Pires, V.M.R.; Alfaia, C.M.; Lopes, P.A.; Martins, S.V.; Pinto, R.M.A.; Prates, J.A.M.. "Restriction of dietary protein does not promote hepatic lipogenesis in lean or fatty pigs". British Journal of Nutrition 115 8 (2016): 1339-1351. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959457981&partnerID=MN8TOARS.
    10.1017/S0007114516000453
  52. Mateus, V.; Rocha, J.; Alves, P.; Mota-Filipe, H.; Sepodes, B.; Pinto, R.M.A.. "Anti-Inflammatory Effect of Erythropoietin in the TNBS-induced Colitis". Basic and Clinical Pharmacology and Toxicology (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85006047651&partnerID=MN8TOARS.
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  109. Sepodes, B.; Rocha, J.; Abdelrahman, M.; Pinto, R.; Oliveira, P.; Thiemermann, C.; Mota-Filipe, H.. "Inhibition of endogenous hydrogen sulphide formation protects the liver from hepatic ischemia-reperfusion injury in the rat". Shock (2006): https://publons.com/wos-op/publon/11850326/.
    10.1097/00024382-200610001-00049
  110. Sepodes, B.; Abdelrahman, M.; Rocha, J.; Pinto, R.; Mota-Filipe, H.; Thiemermann, C.. "A glycogen synthase kinase-3 inhibitor (TDZD-8) attenuates the liver and neuromuscular injury caused by burn in the rat". Shock (2006): https://publons.com/wos-op/publon/11850325/.
    10.1097/00024382-200610001-00064
  111. Reto, Marcia; Almeida, Cristina; Barroso, Isabel; Sepodes, Bruno; Pinto, Rui; Mota-Filipe, Helder; Figueira, Maria-Eduardo. "Hypocholesterolemic effect of green tea and antioxidant effect ofepigallocatechin gallate (EGCG) from green tea". Acta Pharmacologica Sinica (2006): https://publons.com/wos-op/publon/4009973/.
  112. Sepodes, Bruno; Abdelrahman, Maha; Pinto, Rui; Figueira, Maria-Eduardo; Mota-Filipe, Helder; Thiemermann, Christoph. "Glycogen synthase kinase-3b inhibitor, TDZD-8, attenuates the liver injury caused by ischemia-reperfusion in the rat". Acta Pharmacologica Sinica (2006): https://publons.com/wos-op/publon/4009974/.
  113. Pinto, Rui; Barrento, Clara; Sepodes, Bruno; Mota-Filipe, Helder; Lima, Beatriz Silva. "Nitric oxide is involved in the mechanism for the antihypertension action of carvedilol". Acta Pharmacologica Sinica (2006): https://publons.com/wos-op/publon/11850324/.
  114. Sepodes, B; Pinto, R; McDonald, M; Eduardo-Figueira, M; Thiemermann, C; Mota-Filipe, H. "Tyrphostin AG126 reduces ischemia-reperfusion injury of the liver in the rat". Shock (2005): https://publons.com/wos-op/publon/4010034/.
  115. Sepodes, B.; Maio, R.; Pinto, R.; Marques, C.; Mendes-Do-Vale, J.; McDonald, M.C.; Thiemermann, C.; Mota-Filipe, H.. "Tempol, an intracelullar free radical scavenger, reduces liver injury in hepatic ischemia-reperfusion in the rat". Transplantation Proceedings 36 4 (2004): 849-853. http://www.scopus.com/inward/record.url?eid=2-s2.0-2942674742&partnerID=MN8TOARS.
    10.1016/j.transproceed.2004.03.050
  116. Sepodes, B; Pinto, R; McDonald, MC; Thiemermann, C; Mota-Filipe, H. "Effect of recombinant human erythropoietin in a rat model of ischemia-reperfusion injury of the liver". Shock (2004): https://publons.com/wos-op/publon/11850334/.
    10.1097/00024382-200403001-00346
  117. Pinto, R.; Carvalho, R.; Sepodes, B.; Barrento, C.; Mota-Filipe, H.; Silva-Lima, B.. "Involvement of nitric oxide synthase pathway and alpha 1-adrenoceptors in the noradrenaline-release induced by phenylephrine in the rat vas deferens". Fundamental & Clinical Pharmacology (2004): https://publons.com/wos-op/publon/11850337/.
  118. Sepodes, B.; Pinto, R.; McDonald, M.; Thiemermann, C.; Mota-Filipe, H.. "The effect of haemoglobin pretreatment on the liver ischaemia/reperfusion injury". Fundamental & Clinical Pharmacology (2004): https://publons.com/wos-op/publon/11850336/.
  119. Pinto, R.; Barrento, C.; Mota-Filipe, H.; Lima, B.S.. "Phenylephrine Induces Endogenous Noradrenaline Release in the Rat Vas deferens through Nitric Oxide Synthase Pathway". Pharmacology and Toxicology 93 4 (2003): 191-196. http://www.scopus.com/inward/record.url?eid=2-s2.0-0242383350&partnerID=MN8TOARS.
    10.1034/j.1600-0773.2003.930407.x
  120. Pinto, R.; Mota-Filipe, H.; Lima, B.S.. "Nitric oxide synthase/guanylate cyclase pathway modulates the rat vas deferens contractility induced by phenylephrine". Pharmacology and Toxicology 91 4 (2002): 179-184. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036799367&partnerID=MN8TOARS.
    10.1034/j.1600-0773.2002.910405.x
  121. Mota-Filipe, H.; Sepodes, B.; McDonald, M.; Cuzzocrea, S.; Pinto, R.; Thiemermann, C.. "The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat". Medical Science Monitor 8 11 (2002): http://www.scopus.com/inward/record.url?eid=2-s2.0-0036858375&partnerID=MN8TOARS.
  122. Mota-Filipe H; Sepodes B; McDonald MC; Cuzzocrea S; Pinto R; Thiemermann C. "The novel PARP inhibitor 5-aminoisoquinolinone reduces the liver injury caused by ischemia and reperfusion in the rat". Medical Science Monitor (2002): https://publons.com/wos-op/publon/15534757/.
  123. Palma, P; Barata, JD; Branco, P; Pinto, R; Lima, BS. "Dietary supplementation with canned sardine (c.s.) improves the parameters of risk of cardiovascular disease. Study in old male rats". British Journal of Pharmacology (2002): https://publons.com/wos-op/publon/11858523/.
  124. Pinto, R; Mota-Filipe, H; Barrento, C; Lima, BS. "Effect of nitric oxide synthase/guanylate cyclase inhibition on the rat vas deferens contractility and noradrenaline efflux". British Journal of Pharmacology (2002): https://publons.com/wos-op/publon/11858522/.
  125. Sepodes, B; Pinto, R; McDonald, MC; Mota-Filipe, H; Thiemermann, C. "Dithiocarbamates attenuate the organ injury and dysfunction caused by endotoxin in the rat". British Journal of Pharmacology (2002): https://publons.com/wos-op/publon/11850333/.
  126. Palma, P.; Barata, J. D.; Pinto, R.; Mota-Filipe, H.; Silva-Lima, B.. "Effect of dietary supplementation with canned Portuguese sardine (cPs) on serum lipids and the glucose metabolic profile in old male rats". Fundamental & Clinical Pharmacology 15 (2001): 96-96. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208316200563&KeyUID=WOS:000208316200563.
  127. Caneira-da-Silva, M.; Mota-Filipe, H.; Pinto, R.; Albuquerque, L.; Pita, R.; Giao-T-Rico, J. M.. "Effect of L-NAME on blood pressure, liver injury and renal dysfunction in a rat burn scald injury model". Fundamental & Clinical Pharmacology 15 (2001): 69-69. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208316200399&KeyUID=WOS:000208316200399.
  128. Pinto, R.; Barrento, C.; Mota-Filipe, H.; Silva-Lima, B.. "Effect of nitric oxide synthase inhibition in the rat vas deferens contractility and noradrenaline release". Fundamental & Clinical Pharmacology 15 (2001): 85-85. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208316200497&KeyUID=WOS:000208316200497.
  129. Sepodes, B.; Mota-Filipe, H.; Pinto, R.; McDonald, M. C.; Thiemermann, C.. "Pretreatment of rats with hemoglobin reduces the multiple organ dysfunction associated with endotoxic shock". Fundamental & Clinical Pharmacology 15 (2001): 85-85. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000208316200499&KeyUID=WOS:000208316200499.
  130. Pinto, R; Vieira, C; Lima, BS. "Role of N-G-nitro-L-arginine in the rat vas deferens induced contractility by noradrenaline and phenylephrine". British Journal of Pharmacology 127 (1999): U63-U63. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000081651500117&KeyUID=WOS:000081651500117.
  131. Caneira Da Silva, M.D.R.; Mota Filipe, H.; Amaro Pinto, R.M.; Salaverría Timóteo De Carvalho, M.F.; Monteiro Godinho De Matos, M.M.; Cordeiro Ferreira, A.C.; Gião Toscano Rico, J.M.. "Nitric oxide and human thermal injury short term outcome". Burns 24 3 (1998): 207-212. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032078488&partnerID=MN8TOARS.
    10.1016/S0305-4179(98)00014-X
  132. Pinto, R; Vieira, C; Mota-Filipe, H; Lima, BS. "Effect of sodium fluoride on the noradrenaline contractility of the rat vas deferens induced". Naunyn-Schmiedebergs Archives of Pharmacology 358 1 (1998): R258-R258. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000075207700956&KeyUID=WOS:000075207700956.
  133. da Silva, MDC; Filipe, HM; Pinto, RMA; de Carvalho, MFST; de Matos, MMMG; Ferreira, AC; Rico, JMGT. "Nitric oxide and human thermal injury short term outcome". Burns 24 3 (1998): 207-212. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000074556900003&KeyUID=WOS:000074556900003.
    10.1016/S0305-4179(98)00014-X
  134. do Rosario Caneira da Silva, M; Mota Filipe, H; Pinto, R M; Salaverria Timoteo de Carval; Godinho de Matos, M M; Cordeiro Ferreira, A; Toscano Rico, J M. "Nitric oxide and human thermal injury short term outcome.". Burns : journal of the International Society for Burn Injuries 24 3 (1998): 207-12. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:9677022&KeyUID=MEDLINE:9677022.
  135. Vale, F.M.; Castro, M.; Monteiro, J.; Couto, F.S.; Pinto, R.; Rico, J.M.G.T.. "Acrylic bone cement induces the production of free radicals by cultured human fibroblasts". Biomaterials 18 16 (1997): 1133-1135. http://www.scopus.com/inward/record.url?eid=2-s2.0-0008483538&partnerID=MN8TOARS.
    10.1016/S0142-9612(97)00043-4
  136. Catarino, M; Pinto, R; Conde, A; Costa, A; Soares, J; Tavares, C; DeOliveira, CF; Oliveira, HM. "Tissue polypeptide specific antigen (TPS) as a complementary test of CA 125 in ovarian cancer". 10th International Meeting of Gynaecological Oncology (1997): 305-309. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1997BH98T00055&KeyUID=WOS:A1997BH98T00055.
  137. Caneira, M.; Mota-Filipe, H.; Castro, M.; Pinto, R.; Gondinho-Matos, M.; Cordeiro-Ferreira, A.; Toscano Rico, J.M.. "Effect of burn blister fluid on the viability of human cultured fibroblasts | Efecto del contenido liquido de las ampollas causadas por quemaduras, en la viabilidad de los fibroblastos humanos". Cirugia Plastica Ibero-Latinoamericana 22 3 (1996): 231-239.
  138. Caneira, M.; Mota-Filipe, H.; Castro, M.; Pinto, R.; Gondinho-Matos, M.; Cordeiro-Ferreira, A.; Toscano Rico, J.M.. "Effect of burn blister fluid on the viability of human cultured fibroblasts | Efecto del contenido liquido de las ampollas causadas por quemaduras, en la viabilidad de los fibroblastos humanos". Cirugia Plastica Ibero-Latinoamericana 22 3 (1996): 231-239. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029946340&partnerID=MN8TOARS.
  139. Filipe, P.M.; Freitas, J.P.; Castro, M.; Pinto, R.; Fernandes, A.; de Castro, L.C.; Rico, T.; Rodrigo, F.G.. "Lipid peroxidation, production of PGE2 and cellular mortality induced by UV in cultured human skin fibroblasts | Peroxydation lipidique, production de PGE2 et mortalité cellulaire induites par les UV dans des fibroblasts cutanés humains en culture.". Comptes rendus des séances de la Société de biologie et de ses filiales 189 3 (1995): 443-451.
  140. Filipe, P M; Freitas, J P; Castro, M; Pinto, R; Fernandes, A; de Castro, L C; Rico, T; Rodrigo, F G. "[Lipid peroxidation, production of PGE2 and cellular mortality induced by UV in cultured human skin fibroblasts].". Comptes rendus des seances de la Societe de biologie et de ses filiales 189 3 (1995): 443-51. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:8521092&KeyUID=MEDLINE:8521092.
  141. Filipe, P.M.; Freitas, J.P.; Castro, M.; Pinto, R.; Fernandes, A.; de Castro, L.C.; Rico, T.; Rodrigo, F.G.. "Lipid peroxidation, production of PGE2 and cellular mortality induced by UV in cultured human skin fibroblasts | Peroxydation lipidique, production de PGE2 et mortalité cellulaire induites par les UV dans des fibroblasts cutanés humains en culture.". Comptes rendus des séances de la Société de biologie et de ses filiales 189 3 (1995): 443-451. http://www.scopus.com/inward/record.url?eid=2-s2.0-18744428078&partnerID=MN8TOARS.