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Mariana G. Bexiga is an experienced Project Manager and Researcher in the field of Life and Health Sciences, with experience in molecular cardiology, membrane trafficking, and nanotoxicoloty. Mariana graduated in Biochemistry from the University of Coimbra, Portugal, in 2005. She obtained her PhD in Biochemistry, speciality of Molecular Biology, in 2012 from the same University. Her PhD project was developed in University College Dublin, Ireland, and focussed on the molecular and cellular mechanisms of toxicity induced by positively-charged nanoparticles. Mariana has extensive experience in Genome-wide (GW) RNAi screening applied to different fields, in particular membrane trafficking, nanoparticle uptake and toxicity and molecular cardiology. She was the Science Manager for the MIRACLE project, a EU-funded project in the area of photonics and supported management for the RESTORE project. Her roles included managing the communication within and outside of the consortium and managing the exploitation of the products that will arise from the project. Additionally, she supported grant writing for several H2020 calls, with her work contributing to raising close to 9M euro. Mariana has been very successful in procuring individual fellowships. Of note are the highly competitive and prestigious Assistant Researcher contract in the remit of CEEC-Ind 2017 and Marie Sklodowska-Curie Individual fellowship she secured in 2018 and 2016, respectively. She has also received a PhD fellowship from the Portuguese Science Foundation (FCT) and an exchange grant from the European Science Foundation (ESF). Over the years she has also received several awards recognising both her scientific merit as well as her communication skills, of note is the Lindau Nobel Laureate Meeting Fellow award by the Irish Research Council (IRC), which allowed her to represent Ireland in the Lindau Nobel Laureate Meetings. Alongside her research activities, Mariana has extensive experience teaching both at undergraduate and MSc/PhD level. Throughout the years she has also supervised six undergraduate student research projects, one master student project and mentored three PhD students. Mariana also actively participates in Science Communication and Outreach. Mariana has published her work in 12 international peer-reviewed articles and has presented her work in national and international meetings, including 7 oral communications. Over the years, Mariana has been integrated in the team of several research projects funded by European Commission, Science Foundation Ireland (SFI) and FCT.
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Identificação

Identificação pessoal

Nome completo
Mariana Godinho Bexiga

Nomes de citação

  • G. Bexiga, Mariana
  • Bexiga, Mariana G.

Identificadores de autor

Ciência ID
1C1F-C9F9-5372
ORCID iD
0000-0003-2906-4975

Domínios de atuação

  • Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
  • Ciências Naturais - Ciências Biológicas - Biologia Celular
  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências da Engenharia e Tecnologias - Nanotecnologia - Nanomateriais

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Espanhol; Castelhano Utilizador independente (B2) Utilizador proficiente (C2) Utilizador independente (B2) Utilizador proficiente (C2)
Formação
Grau Classificação
2021/10/01 - 2022/04/27
Concluído
 Executive MBA (Outros)
Universidade do Porto Porto Business School, Portugal
2016/05 - 2016/05
Concluído
 Laboratory Animal Science FELASA Category C - Design and direction of animal experiments (Diploma de especialização)
Especialização em Laboratory Animal Science
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015 - 2015
Concluído
 Project Management Certificate (Diploma de especialização)
Especialização em Project Management
Quality Qualifications Ireland, Irlanda
2012/02/22
Concluído
 Bioquímica - Especialidade Biologia Molecular (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Cationic nanoparticles: friend or foe? – Deciphering the mechanisms of cell death induced by cationic nanoparticles" (TESE/DISSERTAÇÃO)
 Aprovado com distincao e louvor por unanimidade
2012/02/22
Concluído
 Bioquímica (Doutoramento)
Especialização em Especialidade: Biologia Molecular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Cationic Nanoparticles: Friend or Foe? Deciphering the mechanisms of cell death induced by cationic nanoparticles" (TESE/DISSERTAÇÃO)
 Aprovada com Distinção e Louvor por Unanimidade
2012 - 2012
Concluído
 Certificado de Competências Pedagógicas (Outros)
Instituto do Emprego e Formação Profissional, Portugal
2010 - 2010
Concluído
 Diplôme d’Études en Langue Française B1 (Outros)
Gouvernement francais Ministere de l'education nationale, França
 17.5
2005/07/08
Concluído
 Bioquímica (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Optimising the Minicircle plasmid for Bioplex targeting to Liver cells" (TESE/DISSERTAÇÃO)
 16/20
2001 - 2001
Concluído
 Certificate of Proficiency in English (Outros)
University of Cambridge, Reino Unido
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento 		Empregador
2023/12/01 - Atual Gestão de Ciência e Tecnologia Universidade Católica Portuguesa Portuguesa Centro de Biotecnologia e Química Fina, Portugal
2021/03/16 - 2023/11/30 Gestão de Ciência e Tecnologia Instituto Nacional de Engenharia Biomédica, Portugal
2019/05/01 - 2021/03/15 Investigador Auxiliar (carreira) (Investigação) CNC.IBILI, Portugal
2018/03/01 - 2019/04/30 Gestão de Ciência e Tecnologia Instituto Nacional de Engenharia Biomédica, Portugal
2016/03/01 - 2018/02/28 Investigador Auxiliar (carreira) (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/11/01 - 2016/02/29 Pós-doutorado (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/03/01 - 2015/08/31 Pós-doutorado (Investigação) University College Dublin School of Biology and Environmental Science, Irlanda
2011/06/01 - 2012/03/01 Investigador visitante (Investigação) Université de Bordeaux, França

Outros

Categoria Profissional
Instituição de acolhimento 		Empregador
2009/01/01 - 2011/06/01 PhD Student Project: Cationic nanoparticles: friend or foe? – Deciphering the mechanisms of cell death induced by cationic nanoparticles University College Dublin School of Biology and Environmental Science, Irlanda
2006/08/15 - 2008/12/31 Researcher Project: Metabolic changes induced by HIV-1 infection of Primary Macrophages. The case of Neurotoxicity University College Dublin, Irlanda
2008/09/01 - 2008/11/30 Visiting Researcher. Project: Metabolic changes induced by HIV-1 infection of Primary Macrophages. The case of Neurotoxicity University of Massachusetts Medical School Program in Molecular Medicine, Estados Unidos
2004/09/01 - 2005/06/01 Visiting student Project: Optimising the Minicircle plasmid for Bioplex targeting to Liver cells Karolinska institutet Institutionen för laboratoriemedicin, Suécia
Projetos

Bolsa

Designação Financiadores
2011/06 - 2012/04 Investigating the effect of cationic nanoparticles on Endoplasmic Reticulum homeostasis
3636
 European Science Foundation

Projeto

Designação Financiadores
2023/03/01 - Atual Recreation of the blood-brain barrier microvasculature network by integrating innovative molecular engineering approaches and 3D printing technologies
2022.01690.PTDC
Investigador
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Em curso
2022/01/01 - Atual Role of mitochondrial-thiol homeostasis in neurodegeneration: implication for amyotrophic lateral sclerosis
EXPL/BTM-TEC/1407/2021
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Associação para a Inovação e Desenvolvimento da FCT
Em curso
2021/03/16 - Atual Molecular Bioengineering in health ERA chair
951723
Project Manager
Instituto Nacional de Engenharia Biomédica, Portugal
 European Commission
Em curso
2018/07/26 - 2021/07/25 Caracterização do papel de microRNAs na fibrose cardíaca através de abordagens de genómica funcional
PTDC/BTM-TEC/29894/2017
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Em curso
2016/10/01 - 2020/06/30 Staphylococcus aureus intracelular: identificação de factores bacterianos e celulares envolvidos na invasão do hospedeiro por estirpes clinicamente relevantes para definição de novas abordagens terapêuticas
Infect-ERA/0001/2015
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

CNC.IBILI, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2016/04/01 - 2019/12/31 Identificação e caracterização funcional de microRNAs reguladores de dano cardíaco por isquemia-reperfusão
PTDC/BIM-MEC/2968/2014
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluído
2019/01/01 - 2019/04/30 RESTORE – User-centred smart nanobiomaterial-based 3D matrices for chondral repair
814558
Outra
Instituto Nacional de Engenharia Biomédica, Portugal
 European Commission
Em curso
2018/03/01 - 2019/04/30 MIRACLE – Mid-infrared arthroscopy innovative imaging system for real-time clinical in depth examination and diagnosis of degenerative joint diseases
780598
Outra
Instituto Nacional de Engenharia Biomédica, Portugal
 European Commission
Em curso
2015/11/01 - 2018/02/28 Combinação de high-throughput screening e análise single-cell para o estudo de RNA regulatórios envolvidos nas etapas iniciais de infecção por Campylobacter
Infect-ERA/0001/2014
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

CNC.IBILI, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2016/03 - 2018/02 Functional high-throughput analysis of the role of microRNAs in cardiac ischemia-reperfusion injury
701096
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
Concluído
2010/03 - 2016/02 Dissecting plasma membrane to endoplasmic reticulum trafficking pathways in mammalian cells – potential new avenues for improved drug delivery
09/IN.1/B2604
Investigador
Science Foundation Ireland
Concluído
2007/12 - 2012/11 BioNanoInteract SRC
SFI/SRC/B1155
Investigador
Science Foundation Ireland
Concluído
Produções

Publicações

Artigo em revista
  1. Panarella, A.; Bexiga, M.G.; Galea, G.; O'Neill, E.D.; Salvati, A.; Dawson, K.A.; Simpson, J.C.. "A systematic High-Content Screening microscopy approach reveals key roles for Rab33b, OATL1 and Myo6 in nanoparticle trafficking in HeLa cells". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84977555667&partnerID=MN8TOARS.
    10.1038/srep28865
  2. G. Bexiga, Mariana. "Poster Sessions". FEBS Journal 282 (2015): 55-422. http://dx.doi.org/10.1111/febs.13339.
    10.1111/febs.13339
  3. Galea, G.; Bexiga, M.G.; Panarella, A.; O'Neill, E.D.; Simpson, J.C.. "A high-content screening microscopy approach to dissect the role of Rab proteins in Golgi-to-ER retrograde trafficking". Journal of Cell Science 128 13 (2015): 2339-2349. http://www.scopus.com/inward/record.url?eid=2-s2.0-84935496100&partnerID=MN8TOARS.
    10.1242/jcs.167973
  4. G. Bexiga, Mariana. "Poster Sessions". FEBS Journal 281 (2014): 65-784. http://dx.doi.org/10.1111/febs.12919.
    10.1111/febs.12919
  5. Bexiga, M.G.; Kelly, C.; Dawson, K.A.; Simpson, J.C.. "RNAi-mediated inhibition of apoptosis fails to prevent cationic nanoparticle-induced cell death in cultured cells". Nanomedicine 9 11 (2014): 1651-1664. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908880951&partnerID=MN8TOARS.
    10.2217/nnm.13.151
  6. Wang, F.; Bexiga, M.G.; Anguissola, S.; Boya, P.; Simpson, J.C.; Salvati, A.; Dawson, K.A.. "Time resolved study of cell death mechanisms induced by amine-modified polystyrene nanoparticles". Nanoscale 5 22 (2013): 10868-10876. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886682963&partnerID=MN8TOARS.
    10.1039/c3nr03249c
  7. Bexiga, M.G.; Simpson, J.C.. "Human diseases associated with form and function of the Golgi complex". International Journal of Molecular Sciences 14 9 (2013): 18670-18681. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884192614&partnerID=MN8TOARS.
    10.3390/ijms140918670
  8. Simpson, J.C.; Joggerst, B.; Laketa, V.; Verissimo, F.; Cetin, C.; Erfle, H.; Bexiga, M.G.; et al. "Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway". Nature Cell Biology 14 7 (2012): 764-774. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863205689&partnerID=MN8TOARS.
    10.1038/ncb2510
  9. Yi, P.; Higa, A.; Taouji, S.; Bexiga, M.G.; Marza, E.; Arma, D.; Castain, C.; et al. "Sorafenib-mediated targeting of the AAA+ ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death". Molecular Cancer Therapeutics 11 12 (2012): 2610-2620. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871382622&partnerID=MN8TOARS.
    10.1158/1535-7163.MCT-12-0516
  10. Varela, J.A.; Bexiga, M.G.; Åberg, C.; Simpson, J.C.; Dawson, K.A.. "Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells". Journal of Nanobiotechnology 10 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84866517033&partnerID=MN8TOARS.
    10.1186/1477-3155-10-39
  11. Bexiga, M.G.; Varela, J.A.; Wang, F.; Fenaroli, F.; Salvati, A.; Lynch, I.; Simpson, J.C.; Dawson, K.A.. "Cationic nanoparticles induce caspase 3-, 7-and 9-mediated cytotoxicity in a human astrocytoma cell line". Nanotoxicology 5 4 (2011): 557-567. http://www.scopus.com/inward/record.url?eid=2-s2.0-80655125242&partnerID=MN8TOARS.
    10.3109/17435390.2010.539713
  12. Fletcher, N.F.; Bexiga, M.G.; Brayden, D.J.; Brankin, B.; Willett, B.J.; Hosie, M.J.; Jacque, J.-M.; Callanan, J.J.. "Lymphocyte migration through the blood-brain barrier (BBB) in feline immunodeficiency virus infection is significantly influenced by the pre-existence of virus and tumour necrosis factor (TNF)-a within the central nervous system (CNS): Studies using an in vitro feline BBB model". Neuropathology and Applied Neurobiology 35 6 (2009): 592-602. http://www.scopus.com/inward/record.url?eid=2-s2.0-70449701529&partnerID=MN8TOARS.
    10.1111/j.1365-2990.2009.01031.x
  13. O'Connor, Clare; Meerschaut, Sofie; Corbett, Danielle; Nemeth, Eszter; Decker, Yann; Batti, Laura; Lukasz, Bartlomiej; et al. "Abstracts of the international neuroimmunology symposium University College Dublin, Dublin, Ireland, 13th–14th March, 2008". Journal of Neuroimmunology 197 2 (2008): 159-176. http://dx.doi.org/10.1016/j.jneuroim.2008.04.005.
    10.1016/j.jneuroim.2008.04.005
Capítulo de livro
  1. Bexiga, Mariana. "Advances in biomarker detection: Alternative approaches for blood-based biomarker detection". 2019.
    10.1016/bs.acc.2019.04.003
  2. Bexiga, Mariana. "Genome-Wide siRNA Screening Using Forward Transfection: Identification of Modulators of Membrane Trafficking in Mammalian Cells.". Estados Unidos, 2016.
    10.1007/978-1-4939-6337-9_4
Tese / Dissertação
  1. Bexiga, Mariana Godinho. "Cationic Nanoparticles: Friend or Foe? Deciphering the mechanisms of cell death induced by cationic nanoparticles". Doutoramento, 2012. http://hdl.handle.net/10316/18398.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2015 A genome-wide RNAi screen to dissect retrograde membrane traffic to the Golgi complex. 40th FEBS Congress
FEBS (Berlin, Alemanha)
2012 Cationic nanoparticles: friend or foe? – Deciphering the mechanisms of cell death induced by cationic nanoparticles.
Interdisciplinary Institute for Neuroscience, Université Bordeaux 2 (Bordeaux, França)
2011 Cationic nanoparticles: friend or foe? – Deciphering the mechanisms of cell death induced by cationic nanoparticles.
EMBL (Grenoble, França)
2010/12 Cationic nanoparticles: friend or foe? – Deciphering the mechanisms of cell death induced by cationic nanoparticles. Won Carmel Humphries Memorial Medal for the Best Presentation. UCD SBES Postgraduate Symposium
School of Biology and Environmental Science - University College Dublin (Dublin, Irlanda)
2009 Investigation of the molecular mechanism of cytotoxicity induced by polystyrene nanoparticles in astrocytes. Won Travel grant (400€). MAC’09 Mitochondria, Apoptosis & Cancer – EMBO Workshop
(Prague, República Checa)
2009 Nanotoxicity: Human Brain under attack. Won Registration Grant (950€) and prize for the Best Contribution for Scientific Discussion 2nd ESF/UB European Summer School in Nanomedicine
(Cascais, Portugal)
2008 Nanoparticles as possible delivery system to the Brain. VI Annual Meeting of the PhD Programme in Experimental Biology and Biomedicine
(Cantanhede, Portugal)
2008 Neurodegeneration in HIV-1 infection: role of CXC chemokines. International Neuroimmunology Symposium
(Dublin, Irlanda)

Orientação

Título / Tema
Papel desempenhado 		Curso (Tipo)
Instituição / Organização
2013 - 2014 Dissecting the Retrograde Pathway using Cholera Toxin: A methodological approach to investigate the subcellular trafficking of cholera toxin
Coorientador
 Molecular and Cell Biology (Licenciatura/Bacharelato)
University College Dublin, Irlanda
2013 - 2014 Localisation of GFP-tagged urea transporters in human intestinal Caco-2 cells
Coorientador
University College Dublin, Irlanda
2010 - 2011 Microscopy based analysis of the secretory pathway
Coorientador
 Molecular and Cell Biology (Licenciatura/Bacharelato)
University College Dublin, Irlanda
2010 - 2011 Functional analysis of microtubule associated protein SPATA7
Coorientador
 Cell and Molecular Biology (Licenciatura/Bacharelato)
University College Dublin, Irlanda

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação) 		Instituição / Organização
2023/01/27 - 2023/01/27 Organisation of the MOBILIsE Launch Event: Molecular Bioengineering: Challenges in Industrial and Clinical Translation - Porto, Portugal https://mobilise.i3s.up.pt/news-events/events/molecular-bioengineering-challenges-in-industrial-and-clinical-translation/ (2023/01/27 - 2023/01/27)
Simpósio
 Instituto Nacional de Engenharia Biomédica, Portugal
2019/07 - 2019/07 "Como reparar um coração partido”, Ocupação Científica de Jovens nas Férias, Ciência Viva – Cantanhede, Portugal. Conception, organisation and implementation of the activity. (2019/09)
Outro (Coorganizador)
 Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2018/03 - 2019/07 Organisation of the first project meeting for the MIRACLE project in Porto, Portugal (2018/06 - 2018/06)
Outro (Coorganizador)
 Instituto Nacional de Engenharia Biomédica, Portugal
2015/01 - 2015 "Cellular Light Show¿, University College Dublin - Ireland. Conception, organisation and implementation of the outreach activity which focussed on the use of microscopy to understand the world around us. It was integrated on the Light & Shadow event organised by UCD's College of Science in the remit of the 2015 Year of Light. (2015/05/23 - 2015/05/23)
Oficina (workshop) (Presidente da Comissão Organizadora)
 University College Dublin, Irlanda
2003 - 2003 Member of the Organisation of 1st National Biochemistry Students Meeting in Coimbra (2003 - 2003)
Encontro (Membro da Comissão Organizadora)
 Universidade de Coimbra, Portugal

Participação em evento

Descrição da atividade
Tipo de evento 		Nome do evento
Instituição / Organização
2019/09 - 2019/09 European Researcher’s Night “Speed dating” and hands-on exhibitions – Coimbra, Portugal
Festival
 European Researcher's Night
2019 - 2019 Semana da Ciência e Tecnologia, hands-on exhibitions to 150 5th and 6th grade students - Oliveira do Hospital, Portugal
Outro
 Semana da Ciência e Tecnologia
2018/09 - 2018/09 Course - Transferência de Conhecimento e Estratégias de Valorização da PI, INPI, Portugal
Outro
 Transferência de Conhecimento e Estratégias de Valorização da PI
Instituto Nacional de Propriedade Industrial, Portugal
2018/09 - 2018/09 Course: Curso Geral de PI, INPI, Portugal
Outro
 Curso Geral de PI
Instituto Nacional de Propriedade Industrial, Portugal
2017/09 - 2017/09 European Researcher's Night "Speed dating" and hands-on exhibitions - Coimbra, Portugal
Festival
 European Researcher's Night
2017/02 - 2017/02 High-content screening identifies microRNAs modulating cardiac fibrosis. Poster presentation at the Keystone Symposia - RNA-Based Approaches in Cardiovascular Disease (X8), Keystone, CO - USA
Conferência
 Keystone Symposia – RNA-Based Approaches in Cardiovascular Disease (X8)
2017 - 2017 "A volta ao mundo com a ciência", Semana da Ciência e Tecnologia - Coimbra, Portugal. Oral presentation and hands-on exhibition
Outro
 Semana da Ciência e Tecnologia
2016/05 - 2016/05 Course: Laboratory Animal Science FELASA Category C – Design and direction of animal experiments, Portugal
Outro
 Laboratory Animal Science FELASA Category C – Design and direction of animal experiments
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015 - 2015 Participation in the 65th Lindau Nobel Laureate Meeting, Lindau - Germany
Conferência
 65th Lindau Nobel Laureate Meeting
2015 - 2015 A genome-wide RNAi screen to dissect retrograde membrane traffic to the Golgi complex. Poster presentation at the 40th FEBS Congress, Berlin - Germany
Conferência
 40th FEBS Congress
2015 - 2015 Managing Your First Research Group
Oficina (workshop)
 Managing Your First Research Group
University College Dublin, Irlanda
2015 - 2015 Design Of Teaching Materials
Oficina (workshop)
 Design Of Teaching Materials
University College Dublin, Irlanda
2015 - 2015 Design & Management Of Classes
Oficina (workshop)
 Design & Management Of Classes
University College Dublin, Irlanda
2015 - 2015 Building Research Leaders
Oficina (workshop)
 Building Research Leaders
University College Dublin, Irlanda
2015 - 2015 Project Management Certificate - FETAC level 6
Outro
 Project Management Certificate
Quality Qualifications Ireland, Irlanda
2014 - 2014 Dissecting the retrograde membrane trafficking pathway using bacterial toxins and nanoparticles: A tale of two genome-wide RNAi screens. Poster presentation at the 2014 UCD Conway Festival of Research & Innovation, Dublin - Ireland
Simpósio
 2014 UCD Conway Festival of Research & Innovation
2014 - 2014 Dissecting the retrograde membrane trafficking pathway using bacterial toxins and nanoparticles: A tale of two genome-wide RNAi screens. Poster presentation at the FEBS EMBO 2014 Conference, Paris - France
Conferência
 FEBS EMBO 2014 Conference
2013 - 2013 EMBL Introductory Course on Fundamentals of Widefield and Confocal Microscopy and Imaging, EMBL, Heidelberg – Germany
Oficina (workshop)
 EMBL Introductory Course on Fundamentals of Widefield and Confocal Microscopy and Imaging, EMBL
European Molecular Biology Laboratory, Alemanha
2012 - 2012 Certificado de Competências Pedagógicas
Outro
 Certificado de Competências Pedagógicas
2009/06 - 2009/06 Nanotoxicity: Human Brain under attack. Oral and Poster presentation at the 2nd ESF/UB European Summer School in Nanomedicine, Cascais - Portugal
Conferência
 2nd ESF/UB European Summer School in Nanomedicine
2008 - 2008 A systematic study of nanoparticle uptake by human brain cells. Poster presentation at the 2nd International Symposium Cellular Delivery of Therapeutics Macromolecules, Cardiff - UK
Conferência
 2nd International Symposium “Cellular Delivery of Therapeutics Macromolecules”
2008 - 2008 Neurodegeneration in HIV-1 infection: role of CXC chemokines. Oral and Poster presentation at the International Neuroimmunology Symposium, Dublin - Ireland
Simpósio
 International Neuroimmunology Symposium
2007 - 2007 Neurodegeneration in HIV-1 infection: role of CXC chemokines. Poster presentation at the V Annual Meeting of the PhD Programme in Experimental Biology and Biomedicine, Coimbra - Portugal
Simpósio
 V Annual Meeting of the PhD Programme in Experimental Biology and Biomedicine”
2007 - 2007 Virology and Nanobiology: The case of lentiviruses (HIV, SIV, FIV). Poster presentation at the UCD Conway Institute of Biomolecular and Biomedical Research, Dublin - Ireland
Simpósio
 UCD Conway Institute of Biomolecular and Biomedical Research
2007 - 2007 Course: “Immunobiology”, Dublin Molecular Medicine Centre, Dublin – Ireland
Outro
 Immunobiology
2005/10 - 2006/05 BEB PhD Programme advanced courses (http://beb.cnbc.pt/courses.asp?c=4), Center for Neuroscience and Cell Biology, Coimbra – Portugal
Outro
 BEB PhD Programme
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Júri de grau académico

Tema
Tipo de participação 		Nome do candidato (Tipo de grau)
Instituição / Organização
2019/09/16 Allele-specific silencing of Machado-Joseph disease
Arguente principal
 Ana Carolina Pinheiro da Silva (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2020 - 2021 European Journal of Clinical Investigation (1365-2362) John Wiley & Sons Ltd
2020/02 - 2020/02 Methods (10462023) Elsevier
2016 - 2016 Theranostics (1838-7640) Ivyspring International Publisher
2014 - 2014 Particle and Fibre Toxicology (1743-8977) Springer (Biomed Central Ltd.)

Comissão de avaliação

Descrição da atividade
Tipo de assessoria 		Instituição / Organização Entidade financiadora
2020/03 - 2020/05 Expert evaluator of 4 applications to the AIAS-COFUND II FELLOWSHIPS 2020/2021.
Avaliador
 Aarhus University Aarhus Institute of Advanced Studies, Dinamarca EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
2019/09 - 2019/11 Expert Evaluator for 4 applications to the MSCA-IF scheme.
Avaliador
 EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2016 - 2016 Case studies: RNAi screenings for gene and microRNA function BEB PhD Programme (Curso de doutoramento (conclusão de unidades curriculares)) CNC.IBILI, Portugal
2014/02 - 2015/03 Advanced Cell Biology (CELB30090) Advanced Cell Biology (Bachelor) University College Dublin, Irlanda
2014 - 2015 Scientific Enquiry (SCI10010) Scientific Enquiry (Bachelor) University College Dublin, Irlanda
2014 - 2015 Biological Systems (BIOL20030) Biological Systems (Bachelor) University College Dublin, Irlanda
2014 - 2014 High-content screening microscopy (CELB40160) High-content screening microscopy (Master) University College Dublin, Irlanda
2014 - 2014 Advanced Biological Imaging (CNWY40120) Advanced Biological Imaging (Master) University College Dublin, Irlanda
2011 - 2011 Research Methods in Cell Biology (CELB30080) Research Methods in Cell Biology University College Dublin, Irlanda
2011 - 2011 Practical Fluorescence Microscopy (CELB40100) Practical Fluorescence Microscopy (Master) University College Dublin, Irlanda
2009 - 2010 Advanced Cell Biology (CELB30070) Advanced Cell Biology (Bachelor) University College Dublin, Irlanda
2009 - 2009 Medical Zoology (ZOOL10010) Medical Zoology (Bachelor) University College Dublin, Irlanda

Membro de associação

Nome da associação Tipo de participação
2005 - Atual Sociedade Portuguesa de Bioquimica / Society for Biochemistry Member

Membro de comissão

Descrição da atividade
Tipo de participação 		Instituição / Organização
2020/02 - Atual Reviewing Editor for the journal Experimental Results (ISSN: 2516-712X), published by Cambridge University Press, for the Life Science and Biomedicine area.
Membro
 Cambridge University Press, Reino Unido
2014/01 - 2015/09 Deputy member of the School of Biology and Environmental Science Advisory Board
Membro
 University College Dublin School of Biology and Environmental Science, Irlanda
2001/10 - 2004/09 Member of the Pedagogic Committee - Biochemistry Department
Membro
 Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2002 - 2003 Member of the Biochemistry students’ nucleus of Coimbra's Academic Association
Membro
 Universidade de Coimbra, Portugal

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2014/08/01 - 2014/09/30 Participation in the Selection Committee for a Postdoctoral Fellow position at the School of Biology and Environmental Science, UCD, Ireland. University College Dublin School of Biology and Environmental Science, Irlanda

Tutoria

Tópico Nome do aluno
2015 - 2015 Niamh Morgan
2011 - 2015 George Galea
2011 - 2015 Angela Panarella
2013 - 2013 Anais Tatry
2013 - 2013 Steven Culligan
2006 - 2007 Stephen Kearney
Distinções

Prémio

2010 Carmel Humphries Memorial Medal
University College Dublin School of Biology and Environmental Science, Irlanda
2009 Best Contribution for Scientific Discussion

Outra distinção

2018 Assistant Researcher contract - Scientific employment stimulus call (CEECIND/02895/2017; 344,060€) 10/10; top 0.4% of 1270 applicants
Fundação para a Ciência e a Tecnologia, Portugal
2016 Marie Sklodowska-Curie Individual Fellowship (148,635.50€)
European Commission, Bélgica
2015 Lindau Nobel Laureate Meeting Fellow Award (5,500€)
Irish Research Council, Irlanda
2015 FEBS Bursary to attend the 40th FEBS congress in Berlin (200€)
Federation of European Biochemical Societies, Reino Unido
2014 UCD Seed Funding – Dissemination and Outputs – Publications (280€)
University College Dublin, Irlanda
2011 EpitopeMap exchange grant (Grant number: 3636) (11,400€)
European Science Foundation, França
2009 Travel grant (400€)
2009 Registration grant (950€)
2005 PhD Fellowship (SFRH/BD/15892/2005) (146,000€)
Fundação para a Ciência e a Tecnologia, Portugal
2004 Erasmus Programme Fellowship
Universidade de Coimbra, Portugal

European Commission, Bélgica