BSc Chemistry and Biochemistry from the universities of Burgos and Salamanca, respectively. I received my Ph.D. from the University of Burgos in 2009 for a work developed at the Group of Bioinspired Materials (Instituto de Ciencia de Materiales de Madrid, CSIC). Later I joined the Recombinant Protein Production Group at NUI Galway as IRSCET postdoctoral fellow. Since 2014 I have been working at the Surface Science Group at TEMA (Centre for Mechanical Technology and Automation), University of Aveiro. My research interest spans over multidisciplinary fields in nanostructured materials, surface science, wet chemistry, biomaterials, microbiology and biotechnology. * Surfaces, interfaces, thin films and coatings * Structural and electronic properties of nanostructures on surfaces * 2D materials such as graphene, graphene oxide, reduced graphene oxide, hexagonal Boron Nitride (h-BN) and Transition Metal Dichalcogenides (MoS2, WS2) and their functionalization * Devices based on functionalized surfaces: supercapacitors, solar cells, catalysts, sensors During the last 5 years I publish several high impact factor papers in peer reviewed international journal, including: Applied Materials Today, International Journal of Hydrogen Energy, Journal of Physical Chemistry C, Nanomaterials, Ecotoxicology and Environmental Safety, Carbon, Journal of Materials Chemistry B and ACS Applied Materials and Interfaces. Experimental techniques: Materials characterization: XPS, UPS, AES, SEM, TEM, FT-IR, UV-Vis, XRD, ARAMIS. Molecular biology techniques: cloning, protein expression, purification, enzyme immunoassays. Use of specialized XPS data processing software Prodigy (for controlling multitechnique XPS system of TEMA), and data analysis: CasaXPS, XPS peak, Igor, Origin Writing of scientific manuscripts Mentoring of students in the laboratory work

Identificação pessoal

Nome completo
Maria Jesus Hortiguela Gallo

Nomes de citação

  • María J. Hortigüela

Identificadores de autor

Ciência ID


Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Nanotecnologia - Nanomateriais
  • Ciências da Engenharia e Tecnologias - Engenharia dos Materiais


Idioma Conversação Leitura Escrita Compreensão Peer-review
Espanhol; Castelhano (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Português Utilizador independente (B1) Utilizador proficiente (C1) Utilizador elementar (A2) Utilizador independente (B1)
Grau Classificação
PhD by University of Burgos (Department of Chemistry) (Doctor)
Universidad de Burgos, Espanha
Sobresaliente "cum laude"
Cell signaling and associated pathologies (Señalización celular y patologías asociadas) (DEA)
Universidad de Burgos, Espanha
BsC in Biochemistry (Bachelor)
Universidad de Salamanca, Espanha
BsC in Chemistry (Bachelor)
Universidad de Burgos, Espanha
Percurso profissional


Categoria Profissional
Instituição de acolhimento
2017/12/01 - 2019/10/31 Pós-doutorado (Investigação) Universidade de Aveiro Centro de Tecnologia Mecânica e Automação, Portugal
Universidade de Aveiro Centro de Tecnologia Mecânica e Automação, Portugal
2014/04 - 2017/11 Estagiário de Investigação (Investigação) Universidade de Aveiro Centro de Tecnologia Mecânica e Automação, Portugal
Universidade de Aveiro Centro de Tecnologia Mecânica e Automação, Portugal
2010/10/01 - 2012/09/30 Pós-doutorado (Investigação) National University of Ireland Galway, Irlanda
National University of Ireland Galway Discipline of Microbiology, Irlanda
2006/09 - 2010/06 Estagiário de Investigação (Investigação) Instituto de Ciencia de Materiales de Madrid, Espanha
Instituto de Ciencia de Materiales de Madrid, Espanha


Categoria Profissional
Instituição de acolhimento
2005/12 - 2006/08 Practical training grant for graduates in the area of animal health and laboratory techniques Laboratorio Central de Veterinaria (LCV Algete), Espanha
Laboratorio Central de Veterinaria (Agete) / Ministerio de Agricultura, Pesca y Alimentación, Espanha
2003/06/01 - 2004/05/31 Collaboration agreement to implement the practical training of fellows in receiving entities Chemical Iberica P.V. Veterinary products, Espanha
Chemical Iberica P.V. Veterinary products, Espanha


Designação Financiadores
2010/10/01 - 2012/09/30 Monolithic silica columns for environmental monitoring applications
Bolseiro de Pós-Doutoramento
Irish Research Council for Science, Engineering and Technology, Irlanda

National University of Ireland Galway Discipline of Microbiology, Irlanda
Irish Research Council for Science, Engineering and Technology
2006/09/01 - 2007/08/31 Encapsulation of biological material in inorganic supports (Biocers)
Announcement at BOE 11/04/06
Bolseiro de Iniciação Científica
Instituto de Ciencia de Materiales de Madrid, Espanha

Consejo Superior de Investigaciones Científicas, Espanha
Consejo Superior de Investigaciones Científicas

Fundación Mapfre


Designação Financiadores
2017/12 - 2019/10 On-surface synthesis of functional nanostructures
FCT/ IF/01054/2015
Bolseiro de Pós-Doutoramento
Em curso
2018/10/01 - 2018/12/31 Development of a gas sensor based on 2D materials
PROT IERA 3rd edition
Desenvolvimento técnico


Artigo em conferência
  1. Moreno-Vicente, C.; Abarrategi, A.; Gutiérrez, M.C.; Civantos, A.; Hortigüela, M.J.; Ramos, V.; Aranaz, I.; et al. "Multiwall carbon nanotube scaffolds: A tissue engineering application". Trabalho apresentado em 8th World Biomaterials Congress, Amsterdam, 2008.
Artigo em revista
  1. María J. Hotigüela; Denise Machado; Igor Bdikin; Gonzalo Otero-Irurueta. "Chemical Changes of Graphene Oxide Thin Films Induced by Thermal Treatment under Vacuum Conditions". Coatings 10 2 (2020): 113. https://www.mdpi.com/2079-6412/10/2/113.
    Acesso aberto • Publicado • 10.3390/coatings10020113
  2. Girão, A.F.; Sousa, J.; Domínguez-Bajo, A.; González-Mayorga, A.; Bdikin, I.; Pujades-Otero, E.; Casañ-Pastor, N.; et al. "3D Reduced Graphene Oxide Scaffolds with a Combinatorial Fibrous-Porous Architecture for Neural Tissue Engineering". ACS Applied Materials and Interfaces 12 35 (2020): 38962-38975. http://www.scopus.com/inward/record.url?eid=2-s2.0-85090273715&partnerID=MN8TOARS.
  3. Okhay, O.; Tkach, A.; Gallo, M.J.H.; Otero-Irurueta, G.; Mikhalev, S.; Staiti, P.; Lufrano, F.. "Energy storage of supercapacitor electrodes on carbon cloth enhanced by graphene oxide aerogel reducing conditions". Journal of Energy Storage 32 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85090597393&partnerID=MN8TOARS.
  4. María J. Hortigüela; Gonzalo Otero-Irurueta. "XPS study of the thermal vapour sulfurization of tungsten thin films". Nanomaterials Science & Engineering 1 1 (2019): 6-9. https://proa.ua.pt/index.php/nmse/article/view/6757.
    Acesso aberto • 10.34624/nmse.v1i1.6757
  5. Hortigüela, María J.; Bdikin, Igor; Otero-Irurueta, Gonzalo. "Thermal vapor sulfurization of molybdenum layers". Thin Solid Films 691 (2019): 137588. http://dx.doi.org/10.1016/j.tsf.2019.137588.
  6. Machado, Denise; Hortigüela, Maria J.; Otero-Irurueta, Gonzalo; Marques, Paula A.A.P.; Silva, Ricardo; Silva, Rui F.; Neto, Victor. "Graphene Based Sensors for Air Quality Monitoring – Preliminary Development Evaluation". Journal of Coating Science and Technology 6 1 (2019): 10-21. http://dx.doi.org/10.6000/2369-3355.2019.06.01.2.
  7. Sebastian Zlotnik; Marisa Maltez-da Costa; Nathalie Barroca; María J. Hortigüela; Manoj Kumar Singh; Maria Helena V. Fernandes; Paula Maria Vilarinho. "Functionalized Ferroelectric Coatings Driven Enhanced Biomineralization and Protein Conformation on Metallic Implants". Journal of Materials Chemistry B 7 (2019): 2177-2189. https://pubs.rsc.org/en/content/articlelanding/2019/tb/c8tb02777c#!divAbstract.
    Publicado • 10.1039/C8TB02777C
  8. Nuño, Manuel; Adamaki, Vaia; Tobaldi, David M.; Hortigüela Gallo, Maria J.; Otero-Irurueta, Gonzalo; Bowen, Chris R.; Ball, Richard J.. "Solid-Gas Phase Photo-Catalytic Behaviour of Rutile and TiOn (1 < n < 2) Sub-Oxide Phases for Self-Cleaning Applications". Materials 12 1 (2019): 170. http://dx.doi.org/10.3390/ma12010170.
    Acesso aberto • 10.3390/ma12010170
  9. Zlotnik, S.; Maltez-Da Costa, M.; Barroca, N.; Hortigüela, M.J.; Singh, M.K.; Fernandes, M.H.V.; Vilarinho, P.M.. "Functionalized-ferroelectric-coating-driven enhanced biomineralization and protein-conformation on metallic implants". Journal of Materials Chemistry B 7 13 (2019): 2177-2189. http://www.scopus.com/inward/record.url?eid=2-s2.0-85063467044&partnerID=MN8TOARS.
  10. Olena Okhay; Sebastian Zlotnik; Wenjie Xie; Krzysztof Orlinski; Maria J. Hortiguela Gallo; Gonzalo Otero-Irurueta; Antonio J. S. Fernandes; et al. "Thermoelectric performance of Nb-doped SrTiO3 enhanced by reduced graphene oxide and Sr deficiency cooperation". Carbon 143 (2018): 215-222. https://www.sciencedirect.com/science/article/pii/S0008622318310467.
  11. Susana Loureiro; Sandra Filipe Gonçalves; Gil Gonçalves; Maria Jesús Hortiguela; Sandra Rebelo; Marta Carmona Ferro; Mercedes Vila. "Eco-friendly profile of pegylated nano-graphene oxide at different levels of an aquatic trophic chain". Ecotoxicology and Environmental Safety 162 (2018): 192-200. https://www.sciencedirect.com/science/article/pii/S0147651318305670?via%3Dihub.
  12. María J. Hortigüela. "Eco-friendly profile of pegylated nano-graphene oxide at different levels of an aquatic trophic chain". (2018):
  13. Sharma, D.K.; Ramana, E.V.; Fateixa, S.; Hortigüela, M.J.; Otero-Irurueta, G.; Nogueira, H.I.S.; Kholkin, A.. "Pressure-dependent large area synthesis and electronic structure of MoS2". Materials Research Bulletin 97 (2018): 265-271. https://www.sciencedirect.com/science/article/pii/S0025540817331070.
  14. Bdikin, I.; Sharma, D.K.; Otero-Irurueta, G.; Hortigüela, M.J.; Tyagi, P.K.; Neto, V.; Singh, M.K.. "Charge injection in large area multilayer graphene by ambient Kelvin probe force microscopy". Applied Materials Today 8 (2017): 18-25. https://www.sciencedirect.com/science/article/pii/S2352940716301883.
  15. Ramana, E.V.; Prasad, N.V.; Tobaldi, D.M.; Zavašnik, J.; Singh, M.K.; Hortigüela, M.J.; Seabra, M.P.; Prasad, G.; Valente, M.A.. "Effect of samarium and vanadium co-doping on structure, ferroelectric and photocatalytic properties of bismuth titanate". RSC Advances 7 16 (2017): 9680-9692. http://www.scopus.com/inward/record.url?eid=2-s2.0-85011872340&partnerID=MN8TOARS.
  16. Cicuéndez, M.; Silva, V.S.; Hortigüela, M.J.; Matesanz, M.C.; Vila, M.; Portolés, M.T.. "MC3T3-E1 pre-osteoblast response and differentiation after graphene oxide nanosheet uptake". Colloids and Surfaces B: Biointerfaces 158 (2017): 33-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021202890&partnerID=MN8TOARS.
  17. Tobaldi, D.M.; Hortigüela Gallo, M.J.; Otero-Irurueta, G.; Singh, M.K.; Pullar, R.C.; Seabra, M.P.; Labrincha, J.A.. "Purely Visible-Light-Induced Photochromism in Ag-TiO2 Nanoheterostructures". Langmuir 33 20 (2017): 4890-4902. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019928887&partnerID=MN8TOARS.
  18. Sharma, D.K.; Fateixa, S.; Hortigüela, M.J.; Vidyasagar, R.; Otero-Irurueta, G.; Nogueira, H.I.S.; Singh, M.K.; Kholkin, A.. "Defect concentration in nitrogen-doped graphene grown on Cu substrate: A thickness effect". Physica B: Condensed Matter 513 (2017): 62-68. http://www.scopus.com/inward/record.url?eid=2-s2.0-85014725410&partnerID=MN8TOARS.
  19. Sundar, L.S.; Hortiguela, M.J.; Singh, M.K.; Sousa, A.C.M.. "Thermal conductivity and viscosity of water based nanodiamond (ND) nanofluids: An experimental study". International Communications in Heat and Mass Transfer 76 (2016): 245-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973382913&partnerID=MN8TOARS.
  20. Pukazhselvan, D.; Nasani, N.; Pérez, J.; Hortigüela, M.J.; Yang, T.; Bdikin, I.; Fagg, D.P.. "Two step mechanochemical synthesis of Nb doped MgO rock salt nanoparticles and its application for hydrogen storage in MgH2". International Journal of Hydrogen Energy 41 27 (2016): 11716-11722. http://www.scopus.com/inward/record.url?eid=2-s2.0-84953426220&partnerID=MN8TOARS.
  21. Hortigüela, M.J.; Yuste, L.; Rojo, F.; Aranaz, I.. "Green synthesis of hierarchically structured silver-polymer nanocomposites with antibacterial activity". Nanomaterials 6 8 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84983283841&partnerID=MN8TOARS.
  22. Jaggernauth, A.; Silva, R.M.; Neto, M.A.; Hortigüela, M.J.; Gonçalves, G.; Singh, M.K.; Oliveira, F.J.; Silva, R.F.; Vila, M.. "Nanographene Oxide Functionalization with Organic and Hybrid Organic-Inorganic Polymers by Molecular Layer Deposition". Journal of Physical Chemistry C 120 42 (2016): 24176-24186. http://www.scopus.com/inward/record.url?eid=2-s2.0-84993991947&partnerID=MN8TOARS.
  23. Hortigüela, M.J.; Aumailley, L.; Srivastava, A.; Cunningham, C.; Anandakumar, S.; Robin, S.; Pandit, A.; Hu, X.; Wall, J.G.. "Engineering recombinant antibodies for polymer biofunctionalization". Polymers for Advanced Technologies 26 12 (2015): 1394-1401. http://www.scopus.com/inward/record.url?eid=2-s2.0-84955189369&partnerID=MN8TOARS.
  24. Hortigüela, M.J.; Wall, J.G.. "Improved detection of domoic acid using covalently immobilised antibody fragments". Marine Drugs 11 3 (2013): 881-895. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875771762&partnerID=MN8TOARS.
    Acesso aberto • 10.3390/md11030881
  25. Hu, X.; Hortigüela, M.J.; Robin, S.; Lin, H.; Li, Y.; Moran, A.P.; Wang, W.; Wall, J.G.. "Covalent and oriented immobilization of scFv antibody fragments via an engineered glycan moiety". Biomacromolecules 14 1 (2013): 153-159. http://www.scopus.com/inward/record.url?eid=2-s2.0-84872578197&partnerID=MN8TOARS.
  26. Hortigüela, M.J.; Aranaz, I.; Gutiérrez, M.C.; Ferrer, M.L.; Del Monte, F.. "Chitosan gelation induced by the in situ formation of gold nanoparticles and its processing into macroporous scaffolds". Biomacromolecules 12 1 (2011): 179-186. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651315888&partnerID=MN8TOARS.
  27. Gutierrez, M.C.; Hortigüela, M.J.; Ferrer, M.L.; Del Monte, F.. "Reply to comment on "highly fluorescent rhodamine B nanoparticles entrapped in hybrid glasses"". Langmuir 24 5 (2008): 2258-2259. http://www.scopus.com/inward/record.url?eid=2-s2.0-41849099977&partnerID=MN8TOARS.
  28. Abarrategi, A.; Gutiérrez, M.C.; Moreno-Vicente, C.; Hortigüela, M.J.; Ramos, V.; López-Lacomba, J.L.; Ferrer, M.L.; del Monte, F.. "Multiwall carbon nanotube scaffolds for tissue engineering purposes". Biomaterials 29 1 (2008): 94-102. http://www.scopus.com/inward/record.url?eid=2-s2.0-35349030396&partnerID=MN8TOARS.
  29. Hortigüela, M.J.; Gutiérrez, M.C.; Aranaz, I.; Jobbágy, M.; Abarrategi, A.; Moreno-Vicente, C.; Civantos, A.; et al. "Urea assisted hydroxyapatite mineralization on MWCNT/CHI scaffolds". Journal of Materials Chemistry 18 48 (2008): 5933-5940. http://www.scopus.com/inward/record.url?eid=2-s2.0-57349144617&partnerID=MN8TOARS.
  30. Gutiérrez, M.C.; García-Carvajal, Z.Y.; Hortigüela, M.J.; Yuste, L.; Rojo, F.; Ferrer, M.L.; Del Monte, F.. "Biocompatible MWCNT scaffolds for immobilization and proliferation of E. coli". Journal of Materials Chemistry 17 29 (2007): 2992-2995. http://www.scopus.com/inward/record.url?eid=2-s2.0-34547169516&partnerID=MN8TOARS.
  31. Gutiérrez, M.C.; Hortigüela, M.J.; Manuel Amarilla, J.; Jiménez, R.; Ferrer, M.L.; Del Monte, F.. "Macroporous 3D architectures of self-assembled MWCNT surface decorated with pt nanoparticles as anodes for a direct methanol fuel cell". Journal of Physical Chemistry C 111 15 (2007): 5557-5560. http://www.scopus.com/inward/record.url?eid=2-s2.0-34247644367&partnerID=MN8TOARS.
  32. Gutiérrez, M.C.; Hortigüela, M.J.; Ferrer, M.L.; Del Monte, F.. "Highly fluorescent rhodamine B nanoparticles entrapped in hybrid glasses". Langmuir 23 4 (2007): 2175-2179. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947127059&partnerID=MN8TOARS.
Capítulo de livro
  1. Manoj Kumar Singh; Dhananjay K. Sharma; Gonzalo Otero-Irurueta; María J. Hortigüela. "CVD of flat monolayer of 2D atomics honeycomb structure and their applications". In Chemical Vapour Deposition (CVD) Advances, Technology and Applications, editado por Kwang-Leong Choy. Taylor & Francis Group, 2019.
  1. Maria J. Hortiguela Gallo; Otero-Irurueta, Gonzalo. X-ray Photoelectron Spectroscopy: a Surface Characterization Technique. Aveiro, Portugal: UA Editora. Universidade de Aveiro. 2019.
Resumo em conferência
  1. M.Miranda; T. Marques; A. Correia; María J. Hortigüela; G. Otero-Irurueta; M. Singh; A. Carreira; F. Araújo; M. Fernandes. "Surface and bulk characterisation of a zirconia implant by XRD and XPS". Trabalho apresentado em EAO congress, Paris, 2016.

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2018 Workshop of X-ray photoelectron spectroscopy (XPS) 3rd International Summer School: Multifunctional Smart Coating and Surfaces
(Aveiro, Portugal)
2017 Workshop of X-ray photoelectron spectroscopy (XPS) 2nd International Summer School: Multifunctional Smart Coating and Surfaces
(Aveiro, Portugal)
2017 Workshop of X-ray photoelectron spectroscopy (XPS) II national meeting on Characterization of Materials, Aveiro, Portugal
(Aveiro, Portugal)


2018 PROT_IERA, action mobilizing entrepreneurial ecosystem of Aveiro region

Outra distinção

2010 Postdoctoral Fellowship
2006 Fellowship for the training of research staff
CSIC-MAPFRE Foundation , Espanha
2005 Practical training fellowship for graduates
Ministry of Rural, Marine and Natural Environment, Espanha
2004 Support for enrolment in doctoral courses
Universidad de Burgos, Espanha
2003 Practical training fellowship
General Foundation of the University of Salamanca, Economic Development Agency from Castilla y León, European Social Fund., Espanha