Catarina Custódio (0A10-D092-BD3C)

Curriculum Vitae

Catarina Custódio

Catarina Custódio holds a BSc degree in Applied Chemistry from Faculty of Science and Technology of New University of Lisbon and a Doctoral Degree in Tissue Engineering, Regenerative Medicine and Stem Cells from University of Minho in a collaboration with the Max Planck Institute for Polymer Research in Germany (2013). In 2014 she was awarded with a FCT Post-doctoral grant to develop a project on the patterning of chitosan hydrogels towards controlling cellular function to enhance endogenous cardiac repair. Currently, she is an Assistant Researcher (CEEC) and Principal Investigator of a national R&D project at CICECO-Aveiro Institute of Materials, University of Aveiro. Her main scientific interests are on novel biomaterials for Tissue Engineering and Regenerative Medicine. Her research has a strong translational focus with the main goal of manipulating microenvironments that cells interact with, to facilitate cell assembly and build functional tissue for customized therapies with a particular attention on cardiovascular disease. So far, she has published more than 50 peer-reviewed papers in high impact international journals, summing more than 1800 citations and an h-index 25 (Scopus at 04/2025). She has been actively involved in writing competitive international and national funding proposals and and has been an ad-hoc reviewer for top-quality international journals. Part of her work is focused in product development and translational research to engineer innovative 3D platforms for cell culture. She is a co-founder of the startup Metatissue (2018). The core competency of the company lies in the design and development of novel soft materials for 3D cell culture.

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Identificação

Identificação pessoal

Nome completo: Catarina Custódio

Nomes de citação

Custódio, Catarina A.

Identificadores de autor

Ciência ID: 0A10-D092-BD3C
ORCID iD: 0000-0003-2967-700X
Google Scholar ID: https://scholar.google.com/citations?user=05NgwUQAAAAJ&hl=pt-PT&oi=ao
Scopus Author Id: 26643851500

Endereços de correio eletrónico

catarinacustodio@ua.pt (Profissional)

Moradas

Department of Chemistry, CICECO - Aveiro Institute of Materials, University of Aveiro. Department of Chemistry, CICECO - Aveiro Institute of Materials University of Aveiro, 3810-193 Aveiro, Portugal, 3810-193, Aveiro, Aveiro, Portugal (Profissional)

Websites

http://compass.web.ua.pt/catarina-custodio/ (Profissional)
http://www.ciceco.ua.pt/catarinacustodio (Académico)

Domínios de atuação

Ciências Médicas e da Saúde - Biotecnologia Médica
Ciências da Engenharia e Tecnologias - Engenharia Médica
Ciências Médicas e da Saúde - Biotecnologia Médica - Tecnologias que envolvem a Manipulação de Células,Tecidos,Órgãos ou todo o Organismo
Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Novos Materiais de Bio-derivados
Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
Ciências Médicas e da Saúde - Medicina Clínica - Sistemas Cardíacos e Cardiovasculares
Ciências Exatas - Química

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão
Inglês	Utilizador independente (B1)	Utilizador proficiente (C1)	Utilizador independente (B1)	Utilizador independente (B1)
Espanhol; Castelhano	Utilizador independente (B1)	Utilizador independente (B1)	Utilizador elementar (A1)	Utilizador independente (B1)
Alemão	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)	Utilizador elementar (A1)
Português (Idioma materno)

Formação

	Grau	Classificação
2025/11 - 2025/11 Concluído	Management Acceleration Program (Outros) NOVA University Lisbon NOVA SBE Venture Lab, Portugal
2013 Concluído	Engenharia de Tecidos, Medicina Regenerativa e Células Estaminais (Doutoramento) Universidade do Minho Escola de Engenharia, Portugal "Immobilization of biomolecules into biodegradable polymeric based substrates for selective recruitment and adhesion of cells for tissue engineering applications" (TESE/DISSERTAÇÃO)	Aprovado
2007 Concluído	Química Aplicada (Licenciatura) Especialização em Biotecnologia Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal "Optimization of the conditions for overexpression of metallothionein in the K-562 cell line" (TESE/DISSERTAÇÃO)	14

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2021/04/01 - Atual	Investigador Auxiliar (carreira) (Investigação)	Universidade de Aveiro CICECO, Portugal
	Universidade de Aveiro Departamento de Química, Portugal (...)
2018/04 - 2021/03/31	Investigador Contratado (Investigação)	Universidade de Aveiro Departamento de Química, Portugal
	Universidade de Aveiro Departamento de Química, Portugal (...)
2016/04/04 - 2018/06/14	Pós-doutorado (Investigação)	Universidade de Aveiro, Portugal
	Universidade de Aveiro CICECO, Portugal (...)
2014/02/01 - 2016/03/31	Pós-doutorado (Investigação)	Universidade do Minho Departamento de Engenharia de Polímeros, Portugal
	Laboratório Associado ICVS 3B's, Portugal
2007/11/01 - 2009/09/30	Investigador (Investigação)	Universidade do Minho Departamento de Engenharia de Polímeros, Portugal
	Laboratório Associado ICVS 3B's, Portugal
2006/02/01 - 2006/07/30	Estagiário de Investigação (Investigação)	Katholieke Universiteit Leuven, Bélgica
	Katholieke Universiteit Leuven Faculteit Wetenschappen, Bélgica

Cargos e Funções

	Categoria Profissional Instituição de acolhimento	Empregador
2018/04/04 - Atual	CEO and Co-founder	METATISSUE, Portugal
	METATISSUE, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2009/10/01 - 2013/10/01	Ph.D. in Tissue Engineering, Regenerative Medicine and Stem Cells, Ph.D. thesis title: Immobilization of biomolecules into biodegradable polymeric based substrates for selective recruitment and adhesi	Universidade do Minho Departamento de Engenharia de Polímeros, Portugal
	Laboratório Associado ICVS 3B's, Portugal
2010/10/18 - 2011/09/05	Visiting PhD student- Development of photosensitive chitosan surfaces for controlled cell attachment	Max-Planck-Institut für Polymerforschung, Alemanha
	Max-Planck-Institut für Polymerforschung, Alemanha
2005/09/01 - 2006/02/01	Trainee- Under supervision of Dr. Alice Pereira	Universidade Nova de Lisboa Departamento de Química, Portugal
	Universidade Nova de Lisboa Departamento de Química, Portugal

Projetos

Bolsa

	Designação	Financiadores
2020/09 - Atual	AMNIOGEL - Extracellular matrix derived products from human placenta to engineer bone microtissues for in vitro disease models 957585 Orientador Universidade de Aveiro CICECO, Portugal	European Research Council
2019 - Atual	HYDROMAN - A new platform for developing 3D humanized in vitro osteosarcoma models for drug screening and validation: Hydrogels based on human platelet lysates HYDROMAN Investigador Institut Jean Lamour, França	Em curso
2025/07/01 - 2028/06/30	Revolucionando Modelos de Doenças e Triagem de Medicamentos com um Sistema Microfisiológico Cardíaco Totalmente Humano Impresso em 3D. COMPETE2030-FEDER-00836800 Investigador responsável Universidade de Aveiro, Portugal Universidade de Aveiro CICECO, Portugal	Em curso
2023/03/01 - 2028/03/31	3D Printing of Ultra-fideLity tissues using Space for anti-ageing solutions on Earth 101099346 Orientador
2023/05 - 2027/10	BioRobot-MiniHeart- Building a human mini-heart in the lab 101070953 Co-Investigador Responsável (Co-IR) METATISSUE, Portugal	Em curso
2023/05 - 2027/05	GUT MICROBIOTA-INDUCED TREGS FOR INFLAMMATORY BOWEL DISEASE (IBD) IMMUNOTHERAPY (MITI2) 101080445 Co-Investigador Responsável (Co-IR)	Em curso
2023/01/01 - 2026/12/31	TheraTools - Innovative tools to treat and model complex cancer environments Grant agreement ID: 101073404 Orientador Universidade de Aveiro, Portugal	Em curso
2021/11/01 - 2026/10/31	REBORN - Full human-based multi-scale constructs with jammed regenerative pockets for bone engineering 883370 Orientador Universidade de Aveiro CICECO, Portugal Universidade de Aveiro Departamento de Química, Portugal	Em curso
2021/09/01 - 2025/08/31	UroPrint-Urinary bladder bioprinting for fully autologous transplantation 964883 Investigador responsável METATISSUE, Portugal	EU Framework Programme for Research and Innovation Future and Emerging Technologies Em curso
2021/01/01 - 2025/01/31	InterLynk - Human Platelet Lysates-based Scaffolds for Interfacial Multi-tissue Repair 953169 Investigador responsável	Horizon 2020 EU Framework Programme for Research and Innovation Industrial Leadership Em curso
2021/03 - 2024/03	Tetrissue- Bioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion PTDC/BTM-MAT/3201/2020 Investigador Universidade de Aveiro CICECO, Portugal Universidade de Aveiro Departamento de Química, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2021/03 - 2024/03	Tetrissue- Bioinspired tile-matching to create ultrastructured bone microtissues in a close-to-native fashion PTDC/BTM-MAT/3201/2020	Fundação para a Ciência e a Tecnologia
2022/06/01 - 2023/05/31	TechTissue - Validate human-based 3D in vitro models for accurate drug discovery and development towards a successful market entry 101072131 Investigador responsável METATISSUE, Portugal	Em curso
2013/01 - 2015/03	Multilayered and hierarchically polymeric particles production for bone tissue engineering using a new biomimetic platform inspired on natural repellent substrates Provided by PTCRIS: 127180 Bolseiro de Investigação	Fundação para a Ciência e a Tecnologia, I.P.

Projeto

	Designação	Financiadores
2019/07/01 - Atual	Une nouvelle plateforme pour développer des modèles d'ostéosarcome in vitro 3D humanisés pour le criblage et la validation de médicaments : Des Hydrogels à base de lysats plaquettaires humains (HYDROMAN) HYDROMAN Institut Jean Lamour, França	Cancéropôle du Grand Ouest Em curso
2018/07/26 - 2021/07/25	Efficient methodologies for the conjugation of natural polysaccharides with peptides to obtain multifunctional membranes for periodontal regeneration. PTDC/QUI-QOR/30771/2017 PTDC/QUI-QOR/30771/2017 Investigador Universidade de Aveiro CICECO, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/07/22 - 2021/07/21	Directing Bone Dynamics Through The Synergistic Action Of Immune Cells With Bioengineered Cell Microfactories Containing Patterned Microplatforms PTDC/BTM-MAT/31064/2017 Investigador Universidade de Aveiro CICECO, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/07/20 - 2021/07/19	High performance multicompartmental spherical capsules for transplantation of multimodal co-cultures of adipose-derived stem cells and pancreatic islets PTDC/BTM-ORG/30770/2017 PTDC/BTM-ORG/30770/2017 Investigador Universidade de Aveiro CICECO, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/07 - 2021/07	PANGEIA- Microencapsulated 3D+ Cancer-Stroma Microtumor-based In vitro Testing Platforms for High-Throughput Screening of Combinatorial Therapies for Pancreatic Cancer PTDC/BTM-SAL/30503/2017 PTDC/BTM-SAL/30503/2017 Investigador Universidade de Aveiro CICECO, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/06/26 - 2021/06/25	PROMENADE - 3D cells colonization in marine-derived hydrogels through controlled micro-channels patterning for bone repair PTDC/BTM-MAT/29830/2017 Investigador Universidade de Aveiro CICECO, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/06/22 - 2021/06/21	BEAT- Platelet Lysate Hydrogels for Myocardial Repair PTDC/BTM-MAT/30869/2017 Investigador responsável Universidade de Aveiro CICECO, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/06/22 - 2021/06/21	DNA Base Pairing-based Supramolecular Self-Sorting Devices: A Molecular Recognition and Biomimetic Technology to Screen Target Cells for Biomedical and Healthcare Applications PTDC/QUI-OUT/30658/2017 Investigador Universidade de Aveiro CICECO, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2015/12 - 2020/11	ATLAS - Bioengineered autonomous cell-biomaterials devices for generating humanised micro-tissues for regenerative medicine 669858 Investigador Universidade de Aveiro CICECO, Portugal	European Research Council Em curso
2019/01/01 - 2019/12/31	CICECO-Instituto de Materiais de Aveiro UID/CTM/50011/2019 LA/P/0006/2020 10.54499/LA/P/0006/2020 Universidade de Aveiro, Portugal Universidade de Aveiro CICECO, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2018/03/01 - 2019/08/31	MICROBONE: Novel 3D platforms to engineer bone microtissues for in vitro disease models info:eu-repo/grantAgreement/EC/H2020/789760/EU Investigador Universidade de Aveiro CICECO, Portugal	European Commission Concluído
2013/05 - 2018/04	ComplexiTE - An integrated multidisciplinary tissue engineering approach combining novel high-throughput screening and advanced methodologies to create complex biomaterials-stem cells constructs 321266 Bolseiro de Pós-Doutoramento Laboratório Associado ICVS 3B's, Portugal	European Research Council Concluído
2016/06/01 - 2016/06/01	3D Bioencapsulated hydrogel(s) Constructs for Organ Printing: From Concept to Reality PTDC/BBB-ECT/3213/2014 Investigador Laboratório Associado ICVS 3B's, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2014/03 - 2015/06	BioSeaGlue - Multifunctional layer-by-layer coatings inspired by mussels that combine bioactivity with superior adhesion for orthopaedic applications Provided by PTCRIS: 133668 Investigador	Fundação para a Ciência e a Tecnologia, I.P.
2012 - 2015	Matryoshkas - Multilayered and hierarchically polymeric particles production for bone tissue engineering using a new biomimetic platform inspired on natural repellent substrates. PTDC/CTM-BIO/1814/2012 Bolseiro de Investigação Laboratório Associado ICVS 3B's, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2007/09/03 - 2010/03/31	PHOTONANOTECH - Photozyme Nanoparticle applications for water purification, textile finishing, photodynamic biomineralization and biomaterial coating https://cordis.europa.eu/project/id/33168 Bolseiro de Investigação Laboratório Associado ICVS 3B's, Portugal	European Research Council Concluído

Produções

Publicações

Artigo em boletim informativo	"Bluepharma-U.Coimbra Award for UA project of bioplatforms for cell culture", https://www.ua.pt/en/news, 2020, https://www.ua.pt/pt/noticias/16/63673. Custódio, Catarina A.; Borges, João F.; Amorim, Sara; Araújo, Ana R.; Moro, Artur J.; Mendes, Leonardo. "The Next Generation of Portuguese Chemists", https://www.chemistryviews.org/, 2018
Artigo em conferência	Bruno M. Ladeira; Maria C. Gomes; Custódio, Catarina A.; Mano, Joao F.. "Recreating the dynamic properties of the ECM through cyclodextrin-mediated assembly of human amniotic membrane". Trabalho apresentado em Jornadas do CICECO 2023, Aveiro, 2023. Bruno M. Ladeira; Maria C. Gomes; Custódio, Catarina A.; Kongchang Wei; Mano, Joao F.. "Leveraging host-guest interactions to produce highly reshapable soft hydrogels from proteins of human origin". Trabalho apresentado em 33rd Annual Conference of the European Society for Biomaterials, ESB2023, Davos, 2023. "A human-based 3D platform to support osteosarcoma spheroid invasion in a tri-culture environment for disease modelling and drug screening applications". Trabalho apresentado em 6th TERMIS World Congress, 2021. Publicado Silva, Joana M.; Custódio, Catarina A.; Reis, R. L.; Mano, J. F.. "Multilayered Hollow Tubes for Cardiovascular Tissue Engineering". Trabalho apresentado em 4th TERMIS World Congress, 2015. Publicado Custódio, Catarina A.; Gasperini L.,; Reis, Rui L.; Mano, João F.. "Cell Type Specific Microspheres Incorporating Growth Factors as Injectable Cell Carriers for Tissue Repair". Trabalho apresentado em 4th TERMIS World Congress, 2015. Publicado Custódio, Catarina A.; Cerqueira, M. T.; Marques, A. P.; Reis, R. L.. "Functional chitosan microcarriers for selective cell attachment and expansion". Trabalho apresentado em TERM STEM, 2014. Publicado Custódio, Catarina A.; Silva, Joana M.; Duarte, Ana R.; Sher Praveen; Neto, Ana I.; Pinho, António; Fonseca, Jaime; Reis, Rui L.; Mano, João F.. "Nanostructured Hollow tubes based on chitosan and alginate multilayers". Trabalho apresentado em TERM STEM 2013, 2013. Publicado Neto, A. I.; Correia, C.R.; Custódio, Catarina A.; Mano, João F.. "Miniaturized droplets-based microarray of chemical and biological high-throughput tests". Trabalho apresentado em TERM STEM, 2013. Publicado Costa, R. R.; Castro-Otero E.; Custódio, Catarina A.; Testera, A.M.; Arias, F.J.; Rodríguez-Cabello, J.C.; Mano, João F.. "Extrapolation of hybrid polysaccharide and recombinant polypeptide multilayer films towards three-dimensional compartmentalization". Trabalho apresentado em TERM STEM, 2013. Publicado Custódio, Catarina A. (0A10-D092-BD3C); Cerqueira, M. T.; Marques, A. P.; Reis, R. L.; João. F. Mano. "Functional cell microcarriers- a new platform for cell separation and expansion". Trabalho apresentado em TERM STEM, 2013. Publicado Costa, R.R.; Custódio, Catarina A.; Arias, F.J.; Rodríguez-Cabello, J.C.; Mano, J. F.. "Self-Assembled Microcapsules with Tunable and Sustained Release of Macromolecules for Tissue Engineering". Trabalho apresentado em TERMIS World Congress 2012, 2012. Publicado Custódio, Catarina A.; Santo, V.E.; Gomes, M.E.; Reis, Rui L.; Mano, João F.. "Development of bioactive constructs through cell crosslinking for tissue regeneration". Trabalho apresentado em TERM STEM, 2012. Publicado Custódio, Catarina A.; Frias, A.M.; Del Campo, A.; Reis, Rui L.; Mano, João F.. "Chitosan membranes for spatially controlled cell adhesion and specific cell recruitment". Trabalho apresentado em 3rd TERMIS World Congress, 2012. Publicado Custódio, Catarina A.; Lima, Ana C.; Alvarez-Lorenzo, C.; Mano, João F.. "Multilayered polymeric particle production using superhydrophobic surfaces methodology for drug delivery and tissue engineering applications". Trabalho apresentado em TERM STEM, 2012. Publicado Costa Rui R.; Custódio, Catarina A.; Arias, F.J.; Rodríguez-Cabello J. C.; Mano, J.F.. "Nanostructured Films Exhibiting Multiple Stimuli Responsive Behavior and Improved Cell Adhesion for Tissue Engineering". Trabalho apresentado em TERMIS-EU 2011, 2011. Publicado Custódio, Catarina A.; Alves, C. M.; Reis, Rui L.; Joao F. Mano. "Immobilization of Biomolecules on Chitosan Surface for Selective Recruitment, Controlled Growth and Differentiation of Cells from Mixed Populations". Trabalho apresentado em TERMIS-EU 2008 Porto Meeting, 2008. Publicado
Artigo em revista	Mariana Dias; Catarina A. Custódio; João F. Mano. "Human protein-based biomaterials in preclinical modelling". Nature Reviews Bioengineering (2026): https://doi.org/10.1038/s44222-026-00425-7. 10.1038/s44222-026-00425-7 Maria C. Mendes; Elisa A. G. Martins; Roman V. Chernozem; Polina V. Chernozem; Catarina C. Custódio; Roman A. Surmenev; Andrei L. Kholkin; Ana S. Silva; João F. Mano. "Osteogenic Differentiation Triggered by Intracellular Magnetoelectric Stimulation of Core–Shell Nanotransducers under Remotely Applied Magnetic Fields". ACS Nano (2025): https://doi.org/10.1021/acsnano.5c10509. 10.1021/acsnano.5c10509 Costa, Marcelo; Middleton, Herbert; Correia, Tiago; Soares, Ana Prates; Ellinghaus, Agnes; Jahn, Denise; Schmidt-Bleek, Oskar; et al. "Injectable, mechanically reinforced human-based nanocomposite for minimal invasive applications". Acta Biomaterialia (2025): https://doi.org/10.1016/j.actbio.2025.12.007. 10.1016/j.actbio.2025.12.007 Lucas S. Ribeiro; João Rocha Maia; Vítor M. Gaspar; Catarina A. Custódio; Emerson R. Camargo; Rita Sobreiro-Almeida; João F. Mano. "Nozzle Jamming Granularized Blood-Derived Proteins for Bioprinting Cell-Instructive Architectures". Aggregate (2025): https://doi.org/10.1002/agt2.70041. 10.1002/agt2.70041 Elisa A.G. Martins; Inês A. Deus; Maria C. Gomes; Ana S. Silva; João F. Mano; Catarina A. Custódio. "Human Chorionic Membrane-derived Tunable Hydrogels for Vascular Tissue Engineering Strategies". Advanced Healthcare Materials (2025): https://doi.org/10.1002/adhm.202401510. 10.1002/adhm.202401510 Monteiro, Cátia F.; Deus, Inês A.; Custódio, Catarina A.; Mano, Joao F.. Autor correspondente: Monteiro, Cátia F.. "Biomaterials meet organ-on-chips – a perspective on tumor modeling". International Materials Reviews (2024): 1. Aceite para publicação • 10.1177/09506608241303436 Cátia F. Monteiro; Catarina R. Almeida; Catarina A. Custódio; João F. Mano. "Modeling 3D Tumor Invasiveness to Modulate Macrophage Phenotype in a Human-Based Hydrogel Platform". Macromolecular Bioscience (2024): https://doi.org/10.1002/mabi.202400227. 10.1002/mabi.202400227 Sobreiro-Almeida, Rita; Santos, Sara C.; Decarli, Monize C.; Costa, Marcelo; Correia, Tiago R.; Babilotte, Joanna; Custódio, Catarina A.; Moroni, Lorenzo; Mano, João F.. "Leveraging Blood Components for 3D Printing Applications Through Programmable Ink Engineering Approaches". Advanced Science 11 47 (2024): https://doi.org/10.1002/advs.202406569. 10.1002/advs.202406569 Martins, Elisa A.G.; Deus, Inês A.; Gomes, Maria; Silva, Ana Sofia; Mano, Joao F.; Custódio, Catarina A.. Autor correspondente: Custódio, Catarina A.. "Human Chorionic Membrane-derived Tunable Hydrogels for Vascular Tissue Engineering Strategies". Advanced Healthcare Materials 2401510 (2024): https://onlinelibrary.wiley.com/doi/epdf/10.1002/adhm.202401510. Publicado Sousa, Joana P.M.; Deus, Inês A.; Monteiro, Cátia F.; Custódio, Catarina A.; Gil, João; Papadimitriou, Lina; Ranella, Anthi; et al. "Amniotic Membrane-Derived Multichannel Hydrogels for Neural Tissue Repair". Advanced Healthcare Materials 13 27 (2024): https://doi.org/10.1002/adhm.202400522. Publicado • 10.1002/adhm.202400522 Caiado Decarli, Monize; Ferreira, Helena P.; Sobreiro-Almeida, Rita; Teixeira, Filipa C.; Correia, Tiago R.; Babilotte, Joanna; Olijve, Jos; et al. "Embedding Bioprinting of Low Viscous, Photopolymerizable Blood-Based Bioinks in a Crystal Self-Healing Transparent Supporting Bath". Small Methods (2024): http://dx.doi.org/10.1002/smtd.202400857. 10.1002/smtd.202400857 Cátia F. Monteiro; Maria C. Gomes; Pankaj Bharmoria; Mara G. Freire; João A. P. Coutinho; Catarina A. Custódio; João F. Mano. "Human Platelet Lysate-Derived Nanofibrils as Building Blocks to Produce Free-Standing Membranes for Cell Self-Aggregation". ACS Nano (2024): https://doi.org/10.1021/acsnano.4c02790. 10.1021/acsnano.4c02790 Cátia F. Monteiro; Inês A. Deus; Inês B. Silva; Iola F. Duarte; Catarina A. Custódio; João F. Mano. "Tumor-On-A-Chip Model Incorporating Human-Based Hydrogels for Easy Assessment of Metastatic Tumor Inter-Heterogeneity". Advanced Functional Materials (2024): https://doi.org/10.1002/adfm.202315940. 10.1002/adfm.202315940 Joana P. M. Sousa; Inês A. Deus; Cátia F. Monteiro; Catarina A. Custódio; Emmanuel Stratakis; João F. Mano; Paula A. A. P. Marques. "Comparative analysis of aligned and random amniotic membrane-derived cryogels for neural tissue repair". Biomaterials Science (2024): https://doi.org/10.1039/D4BM00364K. 10.1039/D4BM00364K Sara C. Santos; Catarina A. Custódio; João F. Mano. "Photocrosslinkable microgels derived from human platelet lysates: injectable biomaterials for cardiac cell culture". Biomaterials Science (2024): https://doi.org/10.1039/D3BM01933K. 10.1039/D3BM01933K Zargarzadeh, Mehrzad; Gomes, Maria C.; Patrício, Sónia G.; Custódio, Catarina A.; Mano, João F.. "A Self-Sustaining Hydrogels with Autonomous Supply of Nutrients and Bioactive Domains for 3D Cell Culture". Advanced Functional Materials 33 48 (2023): http://dx.doi.org/10.1002/adfm.202214372. 10.1002/adfm.202214372 Gomes MC; Pinho AR; Custódio C; Mano JF. "Self-Assembly of Platelet Lysates Proteins into Microparticles by Unnatural Disulfide Bonds for Bottom-Up Tissue Engineering.". Advanced materials (Deerfield Beach, Fla.) (2023): http://europepmc.org/abstract/med/37354139. 10.1002/adma.202304659 Ladeira BMF; Gomes MC; Custódio CA; Mano JF. "High-Throughput Production of Microsponges from Platelet Lysate for Tissue Engineering Applications.". Tissue engineering. Part C, Methods (2022): http://europepmc.org/abstract/med/35343236. 10.1089/ten.tec.2022.0029 "High-Throughput Manufacturing of Microsponges from Methacryloyl Platelet Lysate for Cell Delivery". Tissue Engineering Part C (2022): Em revisão Santos, Sara C.; Custódio, Catarina A.; Mano, João F.. "Human Protein-Based Porous Scaffolds as Platforms for Xeno-Free 3D Cell Culture". Advanced Healthcare Materials (2022): 2102383. http://dx.doi.org/10.1002/adhm.202102383. 10.1002/adhm.202102383 Mehrzad Zargarzadeh; A. Sofia Silva; Cláudia Nunes; Manuel A. Coimbra; Catarina A. Custódio; João F. Mano. "Self-glucose feeding hydrogels by enzyme empowered degradation for 3D cell culture". Materials Horizons (2022): https://doi.org/10.1039/D0MH01982H. 10.1039/D0MH01982H Bruno M. Ladeira; Catarina A. Custódio; João F. Mano. "Core–shell microcapsules: biofabrication and potential applications in tissue engineering and regenerative medicine". Biomaterials Science (2022): https://doi.org/10.1039/D1BM01974K. 10.1039/D1BM01974K Deus, Inês A.; Santos, Sara C.; Custódio, Catarina A.; Mano, João F.. "Designing highly customizable human based platforms for cell culture using proteins from the amniotic membrane". Materials Science and Engineering: C (2021): 112574. http://dx.doi.org/10.1016/j.msec.2021.112574. Publicado • 10.1016/j.msec.2021.112574 Monteiro CF; Custódio CA; Mano JF. "Bioengineering a humanized 3D tri-culture osteosarcoma model to assess tumor invasiveness and therapy response.". Acta biomaterialia (2021): http://europepmc.org/abstract/med/34303015. 10.1016/j.actbio.2021.07.034 Tavares, M.T.; Santos, S.C.; Custódio, C.A.; Farinha, J.P.S.; Baleizão, C.; Mano, J.F.. "Platelet lysates-based hydrogels incorporating bioactive mesoporous silica nanoparticles for stem cell osteogenic differentiation". Materials Today Bio 9 (2021): 100096. http://dx.doi.org/10.1016/j.mtbio.2021.100096. 10.1016/j.mtbio.2021.100096 C. S. Dias; C. A. Custódio; G. C. Antunes; M. M. Telo da Gama; J. F. Mano; N. A. M. Araújo. "Modeling of Cell-Mediated Self-Assembled Colloidal Scaffolds". ACS Applied Materials & Interfaces (2020): https://doi.org/10.1021/acsami.0c13457. 10.1021/acsami.0c13457 Inês A. Deus; João F. Mano; Catarina A. Custódio. "Perinatal tissues and cells in tissue engineering and regenerative medicine". Acta Biomaterialia 110 (2020): 1-14. https://doi.org/10.1016/j.actbio.2020.04.035. 10.1016/j.actbio.2020.04.035 Mehrzad Zargarzadeh; Adérito J.R. Amaral; Catarina A. Custódio; João F. Mano. "Biomedical applications of laminarin". Carbohydrate Polymers 232 (2020): 115774-115774. https://doi.org/10.1016/j.carbpol.2019.115774. 10.1016/j.carbpol.2019.115774 Monteiro, Cátia F.; Santos, Sara C.; Custódio, Catarina A.; Mano, João F.. "Human Platelet Lysates-Based Hydrogels: A Novel Personalized 3D Platform for Spheroid Invasion Assessment". Advanced Science (2020): 1902398. http://dx.doi.org/10.1002/advs.201902398. 10.1002/advs.201902398 C.R. Martins; C.A. Custódio; J.F. Mano. "Multifunctional laminarin microparticles for cell adhesion and expansion". Carbohydrate Polymers 202 (2018): 91-98. https://doi.org/10.1016/j.carbpol.2018.08.029. 10.1016/j.carbpol.2018.08.029 Monteiro, Cátia F.; Custódio, Catarina; Mano, João F.. "Three-Dimensional Osteosarcoma Models for Advancing Drug Discovery and Development". Advanced Therapeutics 2 3 (2018): 1800108. http://dx.doi.org/10.1002/adtp.201800108. Publicado • 10.1002/adtp.201800108 Santos, Sara C.; Custódio, Catarina; Mano, João F.. "Photopolymerizable Platelet Lysate Hydrogels for Customizable 3D Cell Culture Platforms". Advanced Healthcare Materials 7 23 (2018): 1800849. http://dx.doi.org/10.1002/adhm.201800849. Publicado • 10.1002/adhm.201800849 Santos, Sara C.; Sigurjonsson ÓE; Custódio, Catarina; João F. Mano. "Blood Plasma Derivatives for Tissue Engineering and Regenerative Medicine Therapies.". Tissue engineering. Part B, Reviews (2018): http://europepmc.org/abstract/med/29737237. Publicado • 10.1089/ten.teb.2018.0008 Custódio, Catarina; João F. Mano. "Cell Surface Engineering to Control Cellular Interactions". ChemNanoMat 2 5 (2016): 376-384. https://doi.org/10.1002/cnma.201600047. Publicado • 10.1002/cnma.201600047 Silva, J.M.; Custódio, Catarina A.; Reis, R.L.; Mano, J.F.. "Multilayered Hollow Tubes as Blood Vessel Substitutes". ACS Biomaterials Science and Engineering 2 12 (2016): 2304-2314. http://www.scopus.com/inward/record.url?eid=2-s2.0-85006036367&partnerID=MN8TOARS. Publicado • 10.1021/acsbiomaterials.6b00499 Custódio, Catarina A.; Reis, R.L.; Mano, J.F.. "Photo-Cross-Linked Laminarin-Based Hydrogels for Biomedical Applications". Biomacromolecules 17 5 (2016): 1602-1609. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973630001&partnerID=MN8TOARS. Publicado • 10.1021/acs.biomac.5b01736 Rodrigues, L.C.; Custódio, Catarina; Reis, R.L.; Mano, J.F.. "Light responsive multilayer surfaces with controlled spatial extinction capability". Journal of Materials Chemistry B 4 8 (2016): 1398-1403. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959348872&partnerID=MN8TOARS. Publicado • 10.1039/c5tb02606g Oliveira, M.B.; Custódio, C.A.; Gasperini, L.; Reis, R.L.; Mano, J.F.. "Autonomous osteogenic differentiation of hASCs encapsulated in methacrylated gellan-gum hydrogels". Acta Biomaterialia 41 (2016): 119-132. http://www.scopus.com/inward/record.url?eid=2-s2.0-84971601488&partnerID=MN8TOARS. 10.1016/j.actbio.2016.05.033 Martins, N.I.; Sousa, M.P.; Custódio, C.A.; Pinto, V.C.; Sousa, P.J.; Minas, G.; Cleymand, F.; Mano, J.F.. "Multilayered membranes with tuned well arrays to be used as regenerative patches". Acta Biomaterialia (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85018325310&partnerID=MN8TOARS. 10.1016/j.actbio.2017.04.021 Custódio, Catarina A.; Cerqueira, M.T.; Marques, A.P.; Reis, R.L.; Mano, J.F.. "Cell selective chitosan microparticles as injectable cell carriers for tissue regeneration". Biomaterials 43 1 (2015): 23-31. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922996872&partnerID=MN8TOARS. 10.1016/j.biomaterials.2014.11.047 Custódio, Catarina A.; San Miguel-Arranz, V.; Gropeanu, R.A.; Gropeanu, M.; Wirkner, M.; Reis, R.L.; Mano, J.F.; Del Campo, A.. "Photopatterned antibodies for selective cell attachment". Langmuir 30 33 (2014): 10066-10071. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906656874&partnerID=MN8TOARS. Publicado • 10.1021/la502688h Custódio, Catarina A.; Reis, R.L.; Mano, J.F.. "Engineering Biomolecular Microenvironments for Cell Instructive Biomaterials". Advanced Healthcare Materials 3 6 (2014): 797-810. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902243790&partnerID=MN8TOARS. Publicado • 10.1002/adhm.201300603 Neto, A.I.; Correia, C.R.; Custódio, Catarina; Mano, J.F.. "Biomimetic miniaturized platform able to sustain arrays of liquid droplets for high-throughput combinatorial tests". Advanced Functional Materials 24 32 (2014): 5096-5103. http://www.scopus.com/inward/record.url?eid=2-s2.0-84906783657&partnerID=MN8TOARS. Publicado • 10.1002/adfm.201400503 Silva, J.M.; Duarte, A.R.C.; Custódio, Catarina; Sher, P.; Neto, A.I.; Pinho, A.C.M.; Fonseca, J.; Reis, R.L.; Mano, J.F.. "Nanostructured Hollow Tubes Based on Chitosan and Alginate Multilayers". Advanced Healthcare Materials 3 3 (2014): 433-440. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895429567&partnerID=MN8TOARS. Publicado • 10.1002/adhm.201300265 Custódio, Catarina A.; Santo, V.E.; Oliveira, M.B.; Gomes, M.E.; Reis, R.L.; Mano, J.F.. "Functionalized microparticles producing scaffolds in combination with cells". Advanced Functional Materials 24 10 (2014): 1391-1400. http://www.scopus.com/inward/record.url?eid=2-s2.0-84895923617&partnerID=MN8TOARS. Publicado • 10.1002/adfm.201301516 Costa, Rui R.; Custódio, Catarina A.; Arias, Francisco J.; Rodríguez-Cabello, José C.; Mano, João F.. "Nanostructured and thermoresponsive recombinant biopolymer-based microcapsules for the delivery of active molecules". Nanomedicine: Nanotechnology, Biology and Medicine 9 7 (2013): 895-902. http://dx.doi.org/10.1016/j.nano.2013.01.013. Publicado • 10.1016/j.nano.2013.01.013 Ana Catarina Lima; Custódio, Catarina A.; Carmen Alvarez-Lorenzo; João F. Mano. "Polymer Particles: Biomimetic Methodology to Produce Polymeric Multilayered Particles for Biotechnological and Biomedical Applications (Small 15/2013)". Small 9 15 (2013): 2486-2486. http://dx.doi.org/10.1002/smll.201370089. Publicado • 10.1002/smll.201370089 Lima, A.C.; Custódio, Catarina; Alvarez-Lorenzo, C.; Mano, J.F.. "Biomimetic methodology to produce polymeric multilayered particles for biotechnological and biomedical applications". Small 9 15 (2013): 2487-2492. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885181437&partnerID=MN8TOARS. Publicado • 10.1002/smll.201202147 Custódio, Catarina; Frias, A.M.; del Campo, A.; Reis, R.L.; Mano, J.F.. "Selective cell recruitment and spatially controlled cell attachment on instructive chitosan surfaces functionalized with antibodies". Biointerphases 7 1-4 (2012): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871130354&partnerID=MN8TOARS. Publicado • 10.1007/s13758-012-0065-3 Neto, A.I.; Custódio, Catarina A.; Song, W.; Mano, J.F.. "High-throughput evaluation of interactions between biomaterials, proteins and cells using patterned superhydrophobic substrates". Soft Matter 7 9 (2011): 4147-4151. http://www.scopus.com/inward/record.url?eid=2-s2.0-79955026925&partnerID=MN8TOARS. Publicado • 10.1039/c1sm05169e Costa, R.R.; Custódio, Catarina; Arias, F.J.; Rodríguez-Cabello, J.C.; Mano, J.F.. "Layer-by-layer assembly of chitosan and recombinant biopolymers into biomimetic coatings with multiple stimuli-responsive properties". Small 7 18 (2011): 2640-2649. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052779197&partnerID=MN8TOARS. Publicado • 10.1002/smll.201100875 Custódio, Catarina A.; Alves, C. M.; Reis, R. L.; Mano, J. F.. "Immobilization of fibronectin in chitosan substrates improves cell adhesion and proliferation". Journal of Tissue Engineering and Regenerative Medicine 4 4 (2010): 316-323. http://dx.doi.org/10.1002/term.248. Publicado • 10.1002/term.248 Praveen Sher; Catarina A. Custódio; João. F. Mano. "Layer-by-layer assembly: Layer-By-Layer Technique for Producing Porous Nanostructured 3D Constructs Using Moldable Freeform Assembly of Spherical Templates (Small 23/2010)". Small 6 23 (2010): 2643-2643. http://dx.doi.org/10.1002/smll.201090084. Publicado • 10.1002/smll.201090084 Sher, P.; Custódio, Catarina A. (0A10-D092-BD3C); Mano, J.F.. "Layer-by-layer technique for producing porous nanostructured 3D constructs using moldable freeform assembly of spherical templates". Small 6 23 (2010): 2644-2648. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649942073&partnerID=MN8TOARS. Publicado • 10.1002/smll.201001066 Wenlong Song; Diana D. Veiga; Custódio, Catarina A. (0A10-D092-BD3C); João F. Mano. "Superhydrophobic Coatings: Bioinspired Degradable Substrates with Extreme Wettability Properties (Adv. Mater. 18/2009)". Adv. Mater. 21 18 (2009): NA-NA. http://dx.doi.org/10.1002/adma.200990062. Publicado • 10.1002/adma.200990062 Song, W.; Veiga, D.D.; Custódio, Catarina A. (0A10-D092-BD3C); Mano, J.F.. "Bioinspired degradable substrates with extreme wettability properties". Advanced Materials 21 18 (2009): 1830-1834. http://www.scopus.com/inward/record.url?eid=2-s2.0-66749087667&partnerID=MN8TOARS. Publicado • 10.1002/adma.200803680 Costa, R.R.; Custódio, Catarina A. (0A10-D092-BD3C); Testera, A.M.; Arias, F.J.; Rodríguez-Cabello, J.C.; Alves, N.M.; Mano, J.F.. "Stimuli-responsive thin coatings using elastin-like polymers for biomedical applications". Advanced Functional Materials 19 20 (2009): 3210-3218. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350452405&partnerID=MN8TOARS. Publicado • 10.1002/adfm.200900568
Capítulo de livro	Deus, Inês A.; Santos, Sara C.; Monteiro, Cátia F.; Gomes, M. C. ; Custódio, Catarina A.; Mano, Joao F.. "Human protein-based soft materials for tissue engineering applications". In Soft Matter for Biomedical Applications. 2021. Aceite para publicação Custódio, Catarina A.; Santos, Sara C.; Monteiro, Cátia F.; Deus, Inês A.; Gomes, Maria C.; Mano, Joao F.. "Chapter 26: Animal Protein-based Soft Materials for Tissue Engineering Applications". In Animal Protein-based Soft Materials for Tissue Engineering Applications, 660-683. The Royal Society of Chemistry, 2021. 10.1039/9781839161124-00660
Edição de número de revista	Custódio, Catarina A.; Silva, A. Sofia; Clara R. Correia. "Design and Fabrication of Soft Materials". Biomimetics (2020): https://www.mdpi.com/journal/biomimetics/special_issues/soft_materials. Aceite para publicação • Editor
Livro	Custódio, Catarina A.; Deus, Inês; Monteiro, Cátia F.; Santos, Sara C.; Mano, J.F.. Soft Matter for Biomedical Applications. Royal Society of Chemistry. 2021. Aceite para publicação Custódio, Catarina; Reis, R.L.; Mano, J.F.; Del Campo, A.. Smart Polymers and their Applications: Chapter 12 - Smart Instructive Polymer Substrates for Tissue Engineering. Elsevier. 2019. Publicado • 10.1016/c2013-0-16347-7 Custódio, Catarina A.; Reis, R.L.; Mano, J.F.; Del Campo, A.. Smart instructive polymer substrates for tissue engineering. 2014. Publicado • 10.1533/9780857097026.2.301
Poster em conferência	Ladeira, Bruno; Custódio, Catarina A.; Mano, Joao F.. "Engineering mechanical tunability in human-derived materials by combining covalent and supramolecular interactions". Trabalho apresentado em Jornadas CICECO 2025: Navigating the Borders of Knowledge, 2025. Ladeira, Bruno; Custódio, Catarina A.; Mano, Joao F.. Autor correspondente: Ladeira, Bruno. "Combining supramolecular and covalent interactions to achieve mechanical tunability in human dECM-based scaffolds". Trabalho apresentado em SupraLife Final International Conference - Supramolecular Multifunctional Biomaterials & Systems for Biomedical and Healthcare Applications, 2025. LUIZ, MARIA EDUARDA; James P.K. Armstrong; Custódio, Catarina A.; Bakht, Syeda Mahwish; Mano, Joao F.. "Contactless Ultrasound-Induced Cell Alignment for Bioengineered Cardiac Tissue Models". Trabalho apresentado em SupraLife Final International Conference, 2025. Martins, Elisa A.G.; Monteiro, Cátia F.; Luís P. G. Monteiro; Custódio, Catarina A.; Mano, Joao F.. "Guiding Cells Through Directional Freeze Casting of Human Placental Chorionic Membrane". Trabalho apresentado em European Society of Biomaterials (ESB) 2025 Congress, 2025. Costa, Marcelo; Custódio, Catarina A.; Sobreiro-Almeida, Rita; Mano, Joao F.. "Engineering human-based nanocomposite materials to develop complex 3D single and multi-material structures for tissue regeneration". Trabalho apresentado em Supralife Final International Conference, 2025. Monteiro, Cátia F.; Maria Clara Gomes; Bharmoria, Pankaj; Mara G. Freire; Coutinho, Joao A. P.; Custódio, Catarina A.; Mano, Joao F.. "Human protein-based nanofibrils assemble into ultrathin membranes to generate cell-sculpted 3D bone microtissue". Trabalho apresentado em CICECO&I3N - Materials Processing and Nanofabrication WORKSHOP, 2025. Fuentes, Julián; Monteiro, Cátia F.; Beloqui, Ana; Custódio, Catarina A.; Mano, Joao F.. "Human Platelet Lysate-Derived Nanoparticles: A Novel Drug Delivery Platform". Trabalho apresentado em SupraLife Third School, 2025. Costa, Marcelo; H.Middleton; Tiago R. Correia; Custódio, Catarina A.; Sobreiro-Almeida, Rita; Mano, Joao F.. "Engineering tunable hydroxyapatite-human based materials to develop complex 3D structures for multi-tissue regeneration". Trabalho apresentado em SupraLife Third School - Supramolecular Multifunctional Biomaterials, 2025. Monteiro, Cátia F.; Gomes, M. C. ; Pankaj Bharmoria; Mara G. Freire; Coutinho, Joao A. P.; Custódio, Catarina A.; Mano, Joao F.. "Human platelet lysates-derived fibrils as building blocks to produce free-standing membranes for cell self-aggregation". Trabalho apresentado em Jornadas do CICECO, 2024. Bruno M. Ladeira; Maria C. Gomes; Custódio, Catarina A.; Mano, Joao F.. "Harnessing Human Extracellular Matrix to Produce Self-Curing Granular Hydrogels for Cell Delivery". Trabalho apresentado em Jornadas do CICECO 2024, 2024. Deus, Inês A.; Custódio, Catarina A.; Mano, Joao F.. Autor correspondente: Deus, Inês A.. "Microphysiological engineering of cardiac fibrotic tissues using human extracellular matrix for disease modelling". Trabalho apresentado em Annual EUROoCS Conference 2024, 2024. Monteiro, Cátia F.; Deus, Inês A.; Silva, Inês B.; Duarte, Iola F; Custódio, Catarina A.; Mano, Joao F.. "Advancing tumor-on-a-chip by integrating a 3D human-based hydrogel to study invasive and metastatic tumor inter-heterogeneity". Trabalho apresentado em EUROoCS Annual Meeting, 2024. Sobreiro-Almeida, Rita; Santos, Sara C.; Correia, Tiago R.; Decarli, Monize; Costa, Marcelo; Babilotte, Joanna; Custódio, Catarina A.; Moroni, Lorenzo; Mano, Joao F.. Autor correspondente: Sobreiro-Almeida, Rita. "Blood components as basis to engineer highly bioactive and customized implantable biomaterials with programmable architectures". Trabalho apresentado em Bioinspired Materials Gordon Research Conferences, 2024. Martins, Elisa A.G.(821C-E851-B932); Monteiro, Luís P. G.; Custódio, Catarina A.; Mano, Joao F.. "Bioactive human-based cryogels to fabricate bioinspired scaffolds for bone tissue engineering". Trabalho apresentado em SupraLife Second School, 2024. Bruno M. Ladeira; Maria C. Gomes; Custódio, Catarina A.; Mano, Joao F.. Autor correspondente: Bruno M. Ladeira. "Exploiting Cyclodextrin-Protein Interactions to Generate Dynamic Biomaterials from Human Amniotic Membrane". Trabalho apresentado em SupraLife Second School, 2024. Santos, Sara C.; Custódio, Catarina A.; Mano, Joao F.. "Xeno-free cardiac tissue repair enabled by human protein-based microparticles as cell carriers". Trabalho apresentado em Jornadas CICECO 2023, 2023. Monteiro, Cátia F.; Deus, Inês A.; Silva, Inês B.; Duarte, Iola F; Custódio, Catarina A.; Mano, Joao F.. "A tumor-on-a-chip incorporating human-based hydrogels for easy assessment of tumor invasion and metastasis". Trabalho apresentado em Jornadas do CICECO, 2023. Sousa, Joana P.M.; Deus, Inês A.; Monteiro, Cátia F.; Custódio, Catarina A.; Stratakis, Emmanuel; Mano, Joao F.; Marques, Paula A.A.P.. "Amniotic membrane-derived anisotropic hydrogels for neural tissue repair". Trabalho apresentado em 33rd Annual Conference of the European Society for Biomaterials, 2023. Martins, Elisa A.G.; Custódio, Catarina A.; Mano, Joao F.. "Development of bioactive human-based cryogels to fabricate bio-inspired scaffolds for bone tissue engineering". Trabalho apresentado em Ciência 2023, 2023. Monteiro, Cátia F.; Deus, Inês A.; Silva, Inês B.; Duarte, Iola F; Custódio, Catarina A.; Mano, Joao F.. "tumor-on-a-chip incorporating human-based hydrogels for easy assessment of tumor invasion and metastasis". Trabalho apresentado em Microphysiological Systems World Summit, 2023. Bruno M. Ladeira; Maria C. Gomes; Custódio, Catarina A.; Mano, Joao F.. Autor correspondente: Bruno M. Ladeira. "Exploring host-guest interactions between cyclodextrins and proteins to produce supramolecular amniotic membrane hydrogels". Trabalho apresentado em SupraLife First School “Functional Supramolecular Polymeric Biomaterials”, 2023. Monteiro, Cátia F.; Custódio, Catarina A.; Mano, Joao F.. "Bioengineering humanized 3D osteosarcoma models for therapy development – moving from static to dynamic modelling". Trabalho apresentado em Jornadas do CICECO, 2022. "Advanced allogeneic porous matrices for personalized cell culture and tissue engineering". Trabalho apresentado em 6th TERMIS World Congress, 2021. "Human platelet lysates-based hydrogels to assess osteosarcoma spheroid invasiveness in a tri-culture model for drug screening applications". Trabalho apresentado em 31st Annual Conference of the European Society for Biomaterials (ESB 2021), 2021. Santos, Sara C.; Custódio, Catarina A.; Mano, Joao F.. "Human-based protein porous scaffolds as platforms for xeno-free 3D cell culture". Trabalho apresentado em Jornadas do CICECO 2020, 2020. Santos, Sara C.; Custódio, Catarina A.; João F. Mano. "Establishment of xenogeneic platforms for 3D cell culture using human protein-based porous scaffolds". Trabalho apresentado em Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Meeting 2020 (TERMIS EU 2020), 2020. Custódio, Catarina A.; Santos, Sara C.; Monteiro, Cátia F.; Deus, Inês A.; Mano, João F.. "Humanized 3D cell culture models - a new era for engineering tissues". Trabalho apresentado em World Biomaterials Congress 2020, 2020. Santos, Sara C.; Custódio, Catarina A.; Mano, João F.. "Human platelet lysates-based sponges: a solution to culture human cells in serum free conditions". Trabalho apresentado em 11th World Biomaterials Congress WBC 2020, 2020. Cátia F. Monteiro; Custódio, Catarina A.; João. F. Mano. "A human-based 3D platform to support osteosarcoma spheroid invasion for disease modelling applications". Trabalho apresentado em European Chapter of the Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS), Manchester, United Kingdom, 2020. Custódio, Catarina A.; Cátia F. Monteiro; João. F. Mano. "A platelet lysates-based 3D platform for humanized cancer invasion modelling for preclinical research". Trabalho apresentado em EACR-AACR Basic and Translational Research Conference: Tumor Microenvironment, Lisboa, Portugal, 2020. Tavares, Márcia T.; Santos, Sara C.; Farinha, José Paulo S.; Baleizão, Carlos; Custódio, Catarina A.; Mano, João F.. "Platelet Lysate-based Hydrogels Incorporated with Multi-Bioactive Mesoporous Silica Nanoparticles for Stem Cell Osteogenic Differentiation". Trabalho apresentado em Jornadas CICECO 2019, 2019. Monteiro, Cátia F.; Custódio, Catarina A.; Mano, João F.. "Human platelet lysates-based hydrogels as a 3D platform for spheroid invasion assessment". Trabalho apresentado em Jornadas do CICECO, 2019. Custódio, Catarina A.; Catia F. Monteiro; Joao F. Mano. "Human platelet lysates based hydrogels – a novel personalized 3D platform for spheroid invasion assessment". Trabalho apresentado em Jornadas do CICECO, Aveiro, Portugal, 2019. Custódio, Catarina A.; Santos, Sara C.; João. F. Mano. "Human platelet lysates-based hydrogels: a novel platform for tissue engineering applications". Trabalho apresentado em Jornadas do CICECO 2019, 11-12 June 2019, Aveiro, 2019. Custódio, Catarina A.; Sara C. Santos; Catia F. Monteiro; Joao F. Mano. "Designing humanized hydrogels toward tissue engineering and disease modeling". Trabalho apresentado em 13th International Chemical and Biological Engineering Conference (CHEMPOR 2018), Aveiro, Portugal, 2018. Monteiro, Cátia F.; Custódio, Catarina A.; Mano, João F.. "Human platelet lysate based hydrogels – a novel personalized 3D platform for spheroid invasion assessment". Trabalho apresentado em 3rd EACR Conference - Goodbye Flat Biology: In Vivo Inspired Cancer Biology and Therapy, 2018. Custódio, Catarina A.; Martins, C. M.; Mano, João F.. "Designing multifunctional laminarin microparticles for 3D cell culture". Trabalho apresentado em 5th TERMIS World Congress, 2018. Custódio, Catarina A.; Santos, Sara C.; Mano, João F.. "Customized platelet lysate based hydrogels for 3D cell culture". Trabalho apresentado em 5th TERMIS World Congress, 2018. Custódio, Catarina A.; Cátia F. Monteiro; Joao F. Mano. "Humanized In-Vitro 3D Models Of Human Osteosarcoma For Drug Screening And Validation". Trabalho apresentado em 3rd EACR Conference - Goodbye Flat Biology: In Vivo Inspired Cancer Biology and Therapy, Berlin - Germany, 2018. Custódio, Catarina A.; Catia F. Monteiro; Joao F. Mano. "Human platelet lysates based hydrogels – a novel personalized 3D platform for spheroid invasion assessment". Trabalho apresentado em 3rd EACR Conference - Goodbye Flat Biology: In Vivo Inspired Cancer Biology and Therapy, Berlin, Germany, 2018. Custódio, Catarina A.; Monteiro, Cátia F.; Joao F. Mano. "Platelet lysates-based hydrogels for the development of in vitro disease models for osteosarcoma". Trabalho apresentado em Jornadas do CICECO, Aveiro, Portugal, 2018. Monteiro, Cátia F.; Custódio, Catarina A.; Mano, João F.. "Platelet lysate based hydrogels for the development of in vitro disease models for osteosarcoma". Trabalho apresentado em Jornadas do CICECO, 2018. Monteiro, Cátia F.; Custódio, Catarina A.; Mano, João F.. "Humanized In-Vitro 3D Models Of Human Osteosarcoma". Trabalho apresentado em EACR Conference - Goodbye Flat Biology: In Vivo Inspired Cancer Biology and Therapy, Berlin - Germany, 2018. Custódio, Catarina A.; Martins C. M.; Mano, João F.. "Multifunctional Laminarin Microparticles for Cell Adhesion and Expansion". Trabalho apresentado em 6th Portuguese Young Chemists Meeting, Setúbal – Portugal, 2018. Silva J. M.; Custódio, Catarina A.; Reis, Rui L.; Mano, João F.. "Multilayered Hollow Tubes for Cardiovascular Tissue Engineering". Trabalho apresentado em 4th TERMIS World Congress, Boston, USA, 2015. Custódio, Catarina A.; Gasperini L.,; Reis, Rui L.; Joao F. Mano. "Cell Type Specific Microspheres Incorporating Growth Factors as Injectable Cell Carriers for Tissue Repair". Trabalho apresentado em 4th TERMIS World Congress, Boston, USA, 2015. Custódio, Catarina A.; Reis, Rui L.; Mano, João F.. "Functional cell selective microparticles as injectable cell carriers for tissue engineering applications". Trabalho apresentado em TERMIS-Americas 2013 Annual Conference & Exposition, Atlanta, USA, 2013. Custódio, Catarina A.; Cerqueira, M.T.; Marques, A.P.; Reis, Rui L.; Mano, João F.. "Functional cell microcarriers- a new platform for cell separation and expansion". Trabalho apresentado em TERM STEM 2013 & 1st POLARIS Workshop, Porto, 2013. Costa, R.R.; Custódio, Catarina A.; Arias, F.J.; Rodríguez-Cabello J. C.; Mano, J. F.. "Self-Assembled Microcapsules with Tunable and Sustained Release of Macromolecules for Tissue Engineering". Trabalho apresentado em 3rd TERMIS World Congress, 2012, Vienna (Austria), 2012. Custódio, Catarina A.; Frias, A.M.; Del Campo, A.; Reis, Rui L.; Mano, João F.. "Chitosan membranes for spatially controlled cell adhesion and specific cell recruitment". Trabalho apresentado em 3rd TERMIS World Congress, 2012, Vienna (Austria), 2012. Custódio, Catarina A.; Reis, Rui L.; Mano, J. F.; Del Campo, A.. "Photopatterned chitosan for spatially defined cell cocultures". Trabalho apresentado em Euromat 2011, Montpellier, 2011. Costa, R.R.; Custódio, Catarina A.; Arias, F.J.; Rodríguez-Cabello, J.C.; Mano, J.F.. "Buildup of biomimetic and multiple stimuli responsive thin coatings of polysaccharides and recombinant biopolymers". Trabalho apresentado em 2nd Meeting of the Institute for Biotechnology and Bioengineering, 2010. Custódio, Catarina A.; Reis, Rui L.; Mano, João F.. "Comparison of adsorption and covalent attachment of proteins as strategies in surface modification of a natural-origin polymer". Trabalho apresentado em Frontiers in Polymer Science, Mainz, Germany, 2009. Custódio, Catarina A.; Alves, Catarina M; Reis, Rui L.; Mano, João F.. "Immobilization of biomolecules on chitosan surface for selective recruitment, controlled growth and differentiation of cells from mixed populations". Trabalho apresentado em TERMIS-EU 2008 Tissue Engineering International & Regenerative Medicine Society Meeting, 2008. Custódio, Catarina A.; Alves, Catarina M; Reis, Rui L.; Mano, João F.. "Studies of the efficiency of EDC/NHS as molecular-binders to chitosan surfaces". Trabalho apresentado em 5th Marie Curie Conference on "Synthesis and Applications of Self Assembling Materials at nano-scale, 2008.
Pré-impressão	Piedade F; Santos S; Ferreira B; Mano J; Custódio C; Almeida C. "Taking Advantage of 3D Human Cell Culture Platforms to Study Pulmonary Fibrotic Diseases". 2022. http://europepmc.org/abstract/PPR/PPR478044. 10.22541/au.164913677.73849537/v1
Resumo em conferência	Ladeira, Bruno; Maria C. Gomes; Custódio, Catarina A.; Mano, Joao F.. "Biofabrication of injectable granular matrices for cell delivery through the supramolecular assembly of decellularized human tissue". Trabalho apresentado em TERMIS European Congress 2025, Freiburg, 2025. Rufino, A.T.; Dias, Mariana; Mano, Joao F.; Custódio, Catarina A.. "Advancing 3D Cell Culture and Organ-on-Chip Models: hPLMA as a Superior, Biocompatible Alternative to Matrigel with Reduced Immunogenicity and Enhanced Stability". Trabalho apresentado em Tissue Engineering and Regenerative Medicine Society (TERMIS) European Congress 2025, Freiburg, 2025.
Tese / Dissertação	Custódio, Catarina A.. "Immobilization of biomolecules into biodegradable polymeric based substrates for selective recruitment and adhesion of cells for tissue engineering applications". Doutoramento, Universidade do Minho, 2013. https://repositorium.sdum.uminho.pt/handle/1822/28881?mode=full.

Artística / Interpretação

Arte visual

Lucas Ribeiro; João Rocha Maia; Gaspar, Vítor; Custódio, Catarina A.; Emerson Camargo; Sobreiro-Almeida, Rita; Mano, Joao F.. Inside Front Cover: Aggregate Volume 6, Issue 7.
10.1002/agt2.70107

Propriedade Intelectual

Marca registada

2019. "METATISSUE".
Registada

Patente

Sobreiro-Almeida, Rita; Santos, Sara C.; Custódio, Catarina A.; Tiago R. Correia; Mano, Joao F.. 2025. "GLOBULAR PROTEIN-BASED COMPOSITIONS, METHODS AND USES THEREOF". Portugal.
Concedida/Emitida
Mano, Joao F.; Maria C. Gomes; Custódio, Catarina A.. 2024. "PLATELET LYSATE-BASED MICROPARTICLES, METHODS AND USES THEREOF - WO-2024127155-A1". Portugal.
Concedida/Emitida
Mano, Joao F.; Maria C. Gomes; Custódio, Catarina A.. 2024. "MICROPARTICULAS À BASE DE LISADOS DE PLAQUETAS, MÉTODOS DE PREPARAÇÃO E SUAS APLICAÇÕES". Portugal.
Pendente
Custódio, Catarina A.. 2021. "HUMAN PLACENTAL MEMBRANE BASED HYDROGEL COMPOSITION, PROCESSES AND USES THEREOF". Portugal.
Pendente
Custódio, Catarina. 2019. "HYDROGELS BASED ON BLOOD PLASMA COMPONENTS, PROCESS AND USES THEREOF".
Concedida/Emitida
Custódio, Catarina A.; Santos, Sara C.; Inês A. Deus; João. F. Mano. 2019. "HUMAN PLACENTAL MEMBRANE BASED HYDROGEL COMPOSITION, PROCESSES AND USES THEREOF".
Pendente
Custódio, Catarina A.. 2012. "PROCESSO PARA DEPOSIÇÃO DE BIOMATERIAIS EM SUBSTRATOS REPELENTES A ÁGUA E RESULTANTES BIOMATERIAIS".
Permitida

Outros

Empresa spin-off

2018. METATISSUE (JFCC-Biosolutions). Design and development of novel human based soft materials for 3D cell culture.. metatissue.com.

Outra produção

Volumetric Bioprinting of Self-Sustaining Hydrogels and Their Chondrogenic Potential-Manuscript in Preparation. 2024. Zargarzadeh, Mehrzad; Custódio, Catarina A.; João F. Mano; Jos Malda; Levato, Riccardo.
Synthetic organelles as intracellular glucose suppliers for augmented cell viability- Manuscript in Preparation. 2024. Zargarzadeh, Mehrzad; Custódio, Catarina A.; Mano, Joao F..
Platelet Lysate-Based Hydrogels as a 3D Scaffold for Organoid Cultivation-Manuscript in Preparation. 2024. Zargarzadeh, Mehrzad; Custódio, Catarina A.; Mano, Joao F..

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2025/04/16	Inovação na Indústria Farmacêutica: A Relevância das Proteínas Humanas na Criação de Modelos In Vitro Fisiologicamente Relevantes	2ª Edição do Gen Sci Scientific Junior Value (Aveiro, Portugal)
2024/05	Revolutionizing drug screening: harnessing human protein-based materials for ethical and accelerated in vitro testing	12th World Biomaterials Congress, WBC 2024 The Korean Society for Biomaterial (Daegu, Coreia do Sul)
2023/09	Advancing tumor modeling and drug screening with a dynamic system integrating a 3D human-based hydrogel to support spheroid invasion	European Society for Biomaterials ESB2023 European Society for Biomaterials (Davos, Suiça)
2023/09	Leveraging host-guest interactions to produce highly reshapable soft hydrogels from proteins of human origin	European Society for Biomaterials ESB2023 European Society for Biomaterials (Davos, Suiça)
2022/04/01	Tec2Med - Technology And Innovation In Medicine	Tec2Med (Lisboa, Portugal)
2021/11/15	Human protein based platforms for 3D cell culture - a new era for personalized engineering tissues	6th TERMIS World Congress Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS) (Maastricht, Países Baixos)
2021/11/15	An engineered human osteosarcoma-on-a-chip for tumor invasion modelling in a dynamic system	TERMIS World Congress Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS) (Maastricht, Países Baixos)
2021/09/05	Hybrid Multicomponent Laminaran/Platelet lysate-based hydrogels	31st Annual Conference of the European Society for Biomaterials (ESB 2021) European Society for Biomaterials (Porto, Portugal)
2021/09/05	Photocrosslinkable hydrogels from solubilized extracellular matrix of the amniotic membrane	31st Annual Conference of the European Society for Biomaterials (ESB 2021) European Society for Biomaterials (Porto)
2021/09/05	Accelerating drug development with human protein based platforms for in vitro 3D cell culture and disease modelling	31st Annual Conference of the European Society for Biomaterials (ESB 2021) European Society for Biomaterials (Porto, Portugal)
2021/09	Human protein-based sponges for fully xeno-free cell culture platforms	31st Annual Conference of the European Society for Biomaterials (ESB 2021) European Society for Biomaterials (Porto, Portugal)
2020/12/11	A 3D human based hydrogel to support spheroid invasion for disease modelling and drug screening applications	11th World Biomaterials Congress Society For Biomaterials (Reino Unido)
2020/12	Laminarin hydrogels as self-feeding platforms for 3D cell culture	11th World Biomaterials Congress, Glasgow, Scotland Society For Biomaterials (Reino Unido)
2020/05	Laminarin as self-feeding platforms for 3D cell culture	World Biomaterials Congress 2020 (Reino Unido)
2020/05	Human based cell culture platforms for tissue engineering applications	Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Meeting 2020 (TERMIS EU 2020) Tissue Engineering and Regenerative Medicine International Society (Manchester, Reino Unido)
2020/05	A 3D human-based hydrogel to support spheroid invasion for disease modelling and drug screening applications	11th World Biomaterials Congress, Glasgow, Scotland (Glasgow, Reino Unido)
2019/10	Innovative Biomedical System Based on Controlled Enzymatically Degradation of Hydrogels	6th EPNOE International Polysaccharide Conference Cellulose and Renewable Division of the American Chemistry Society (ACS) and Cellulose Society of Japan (CSJ) (Aveiro, Portugal)
2019/05	Human platelet lysate-based hydrogels – a humanized 3D platform for disease modelling guided by tissue engineering	European Chapter of the Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS) Tissue Engineering and Regenerative Medicine International Society (Rhodes, Grécia)
2019/05	Human platelet lysates-based hydrogels: a novel platform for tissue engineering applications	TERMIS European Chapter Meeting 2019 Tissue Engineering and Regenerative Medicine International Society (Rhodes, Grécia)
2018/10	Designing humanized hydrogels toward tissue engineering and disease modeling	13th International Chemical and Biological Engineering Conference (CHEMPOR 2018), Aveiro, Portugal University of Aveiro and Ordem dos Engenheiros (Aveiro, Portugal)
2018/09/20	Biomaterials for Tissue Engineering	Advanced Course on Carbohydrates University of Aveiro (Aveiro, Portugal)
2018/09	Platelet lysate based hydrogels with tunable mechanical properties as platforms for 3D cell culture	9th Annual Meeting of the European Society for Biomaterials European Society for Biomaterials (Maastricht, Países Baixos)
2017/12	Freestanding Multilayered Membranes patterned with Micro-Reservoirs as potential Regenerative Paths.	8th Annual TERMIS - Americas Conference and Exhibition Tissue Engineering and Regenerative Medicine International Society (Charlotte, Estados Unidos)
2014/08	Antibody coated microparticles to fabricate functional 3D constructs in combination with cells	26th Annual Conference European Society for Biomaterials European Society for Biomaterials (Liverpool, Reino Unido)
2014/06	Functional chitosan microcarriers for selective cell attachment and expansion	Termis EU 2014 Tissue Engineering and Regenerative Medicine International Society (Genova, Itália)
2013/05	Functionalized microgels for controlled stem cell proliferation and differentiation	8th International Annual Meeting of the Portuguese Society for Stem Cells and Cell Therapies Portuguese Society for Stem Cells and Cell Therapies (Faro, Portugal)
2013/04	Engineering Functional Microparticles to Fabricate Instructive Cell Microenvironments	Society For Biomaterials - 2013 Annual Meeting & Exposition Society For Biomaterials (Boston, Estados Unidos)
2012/10	Development of bioactive constructs through cell crosslinking for tissue regeneration	TERM STEM 2012 TERM STEM (Guimarães, Portugal)
2011/06	Nanostructured Films Exhibiting Multiple Stimuli Responsive Behavior and Improved Cell Adhesion for Tissue Engineering	European Chapter of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) Tissue Engineering and Regenerative Medicine International Society (Granada, Espanha)
2009/09	Response of Cells on Bioinspired Degradable Substrates with Extreme Wettability Properties	TERMIS 2009 WC Tissue Engineering and Regenerative Medicine International Society (Seoul, Coreia do Sul)
2009/09	Novel Thin Biomimetic Coatings for Polysaccharides with Smart Behavior Based on Recombinant Polymers for Tissue Engineering Applications	2nd World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS) Tissue Engineering and Regenerative Medicine International Society (Seoul, Coreia do Sul)

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2023/11 - Atual	HeartSafe: Developing Human Protein-Based Cardiac Models for Safer Drug Testing and Cardiotoxicity Screening Coorientador	PhD in Biotechnology (Doutoramento) Universidade de Aveiro, Portugal METATISSUE, Portugal
2022/03 - Atual	Scale up of the processing of perinatal tissue to synthesize human based hydrogels to a pilot unit Orientador de Filipe Marques Oliveira	Chemical Engineering (Mestrado) Universidade de Aveiro, Portugal Universidade de Aveiro Departamento de Química, Portugal
2022/02 - Atual	Development of bioactive human based cryogels to fabricate ready-to-use bioinspired scaffolds for bone tissue engineering Coorientador de Elisa Alexandra Gonçalves Martins	Doctoral Program in Biotechnology (Doutoramento) Universidade de Aveiro CICECO, Portugal Universidade de Aveiro Departamento de Química, Portugal
2021/11/11 - Atual	Heart-on-a-chip: a fully-human 3D printed device for disease modelling and drug screening Coorientador de Inês Araújo Deus	Doctorate in Biotechnology (Doutoramento) Universidade de Aveiro CICECO, Portugal Universidade de Aveiro Departamento de Química, Portugal
2021/10 - Atual	Optimization of the synthesis of platforms for 3D culture produced from the amniotic membrane Orientador de Miguel Vigário	Master in Biotechnology (Mestrado) Universidade de Aveiro CICECO, Portugal Universidade de Aveiro Departamento de Química, Portugal
2021/09 - Atual	Are human based materials the future of 3D cell cultures? Orientador de Inês Barbosa Silva	Master in Biotechnology (Mestrado) Universidade de Aveiro CICECO, Portugal Universidade de Aveiro Departamento de Química, Portugal
2021/09 - Atual	Chemical modification of human-derived proteins to develop personalized cell culture platforms and bioinks Orientador	Master in Molecular and Bioengineering Biotechnology (Mestrado) Universidade de Aveiro CICECO, Portugal Universidade de Aveiro Departamento de Química, Portugal
2019/12 - Atual	Chemical modification of human proteins for the preparation of hydrogels with tunable mechanical properties Orientador de Maria Clara Gomes	Junior Researcher hired for the project BEAT (PTDC/BTM-MAT/30869/2017) (Outra) Universidade de Aveiro CICECO, Portugal
2019 - Atual	Human plasma derived hydrogels for myocardial tissue engineering Coorientador de Sara Catarina Nunes da Silva Santos	Doctoral Program in Biotechnology (Doutoramento) Universidade de Aveiro Departamento de Química, Portugal
2019 - Atual	Osteosarcoma-on-a-chip: A physiologically relevant human-based microfluidic platform for drug screening Coorientador de Cátia Filipa Rodrigues Monteiro	Doctoral Program in Biotechnology Universidade de Aveiro Departamento de Química, Portugal
2019 - Atual	Innovative Biomedical System Based on Controlled Enzymatically Degradation of Hydrogels Coorientador de Mehrzad Zargarzadeh	Doctoral Program in Biotechnology (Doutoramento) Universidade de Aveiro Departamento de Química, Portugal
2022/02/15 - 2022/11/15	Development of human platelet-based materials Orientador de Bruno Ladeira	Universidade de Aveiro CICECO, Portugal Universidade de Aveiro Departamento de Química, Portugal
2022/02/15 - 2022/11/15	Development of bioinks derived from the extracellular matrix of the amniotic membrane. Orientador de André Filipe Dias Lima	Universidade de Aveiro CICECO, Portugal Universidade de Aveiro Departamento de Química, Portugal
2020/10/01 - 2021/12/10	Micropatterned platelet lysate based membranes for cardiac tissue regeneration Orientador	Biotecnologia (Mestrado) Universidade de Aveiro, Portugal
2020/10/01 - 2021/12/06	Development of platelet lysate based scaffolds from microcapsules for regeneration post-myocardial infarction Orientador	Biotecnologia (Mestrado) Universidade de Aveiro, Portugal
2021/02/01 - 2021/12	Scale up of a plasma protein hydrogel synthesis process for a pilot unit Orientador	Engenharia Química (Mestrado) Universidade de Aveiro, Portugal
2020/11/01 - 2021/12	Optimization of the synthesis and manufacturing process of platforms for 3D cell culture derived from human blood plasma proteins Orientador	Biotecnologia Universidade de Aveiro, Portugal
2020/01/10 - 2021/11/30	Platelet lysates-based hydrogels as 3D cell culture platforms for cardiac regeneration Orientador	Bioquímica (Mestrado) Universidade de Aveiro, Portugal
2021/01/03 - 2021/11/15	Development of 3D hydrogels for axonal regeneration Coorientador	Biomedical engineering (Mestrado) Universidade de Aveiro Instituto de Biomedicina, Portugal
2020/10 - 2021/11	Behaviour of cells confined to topographic hydrogels Coorientador	Biotecnologia (Mestrado) Universidade de Aveiro, Portugal
2019 - 2021/02/26	Extracellular matrix scaffolds for Cardiac Tissue Engineering Orientador de Elisa Alexandra Gonçalves Martins	Master’s degree in Materials and Biomedical Devices Universidade de Aveiro Departamento de Química, Portugal
2019 - 2021/02/25	Taking advantage of 3D humanized in vitro models to study pulmonary diseases Orientador de Francisca Rodrigues da Piedade	Master in Biochemistry (Mestrado) Universidade de Aveiro Departamento de Química, Portugal
2019/09 - 2021/02/22	Development of a platelet lysates-based hydrogel for nerve regeneration Coorientador	Biomedicina Molecular (Mestrado) Universidade de Aveiro, Portugal
2019 - 2021/02/19	Protein based scaffolds and matrices for 3D cell culture Orientador de Ana Miguel da Silva Loureiro	Master in Biochemistry (Mestrado) Universidade de Aveiro Departamento de Química, Portugal
2020 - 2021	Platelet Lysate Hydrogels for Myocardial Repair Orientador de Inês Araújo Deus	Universidade de Aveiro CICECO, Portugal
2019/02/01 - 2019/10/31	Development and characterization of platelet lysates based hydrogels for cardiac cell culture Orientador de Cátia Filipa Rodrigues Monteiro	Universidade de Aveiro CICECO, Portugal
2018 - 2019	Preparation of a hydrogel from human fetal membranes for 3D cell culture Orientador de Inês Araújo Deus	Master in Biotechnology (Mestrado) Universidade de Aveiro Departamento de Química, Portugal
2017 - 2018	Platelet lysate based gels for the development of in vitro disease models for bone cancer Orientador de Cátia Filipa Rodrigues Monteiro	Master in Biothecnology (Mestrado) Universidade de Aveiro Departamento de Química, Portugal
2017 - 2018	Multifunctional microparticles to produce 3D polymeric structures with controlled organization Orientador de Margarida Seco Martins Marques Neves	Degree in Biotechnology (Licenciatura/Bacharelato) Universidade de Aveiro Departamento de Química, Portugal
2016 - 2017	Development of injectable hydrogels derived from human platelet lysates Orientador de Sara Catarina Nunes da Silva Santos	Master in Biochemistry (Mestrado) Universidade de Aveiro Departamento de Química, Portugal
2016 - 2017	Platelet lysates loaded laminarin microparticles for cell attachment and expansion Orientador de Cláudia Isabel Rodrigues Martins	Master in Biotechnology (Mestrado) Universidade de Aveiro Departamento de Química, Portugal

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2022/03 - Atual	Symposium in the 32nd Annual Conference of the European Society of Biomaterials Title of the symposium: Advances in the design of multifunctional and cell-instructive hydrogels for tissue engineering (2022/09/04 - 2022/09/08) Conferência (Membro da Comissão Científica)	European Society of Biomaterials, França
2019/10/10 - 2019/10/12	Techdays 2019 Aveiro (2019/10/10 - 2019/10/12) Exposição (Coorganizador)	Universidade de Aveiro, Portugal
2017/12 - 2017/12	COST-Training School: Understanding bioadhesion in vitro, December 2017 - Aveiro, Portugal. http://www.enba4.eu/2017/06/28/biomimetic-adhesive-polymers-and-hydrogels/ (2017/12) Conferência (Membro da Comissão Organizadora)	Universidade de Aveiro CICECO, Portugal
2017/11/06 - 2017/11/08	International Symposium on Bioinspired Macromolecular Systems (ISMBS), November 2017 – Aveiro, Portugal (2017/11) Conferência	Universidade de Aveiro CICECO, Portugal
2017/10/12 - 2017/10/14	Techdays 2017 Aveiro (2019/10/12 - 2019/10/14) Exposição (Coorganizador)	Universidade de Aveiro, Portugal
2016/09/15 - 2016/09/17	Techdays 2016 Aveiro (2017/09/15 - 2017/09/17) Exposição (Coorganizador)	Universidade de Aveiro, Portugal
2016/04 - 2016/04	5th Portuguese Young Chemists Meeting (5th PYCheM) and 1st European Young Chemists Meeting (1st EYCheM) http://5pychem.eventos.chemistry.pt/ (2016/04 - 2016/04) Conferência (Presidente da Comissão Organizadora)	Sociedade Portuguesa de Química, Portugal

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2022/02/21 - 2022/02/22	23.ª edição das JorTec – Jornadas Tecnológicas JorTec'22 Engenharia Biomédica - Engenharia de Tecidos Mesa-redonda	JorTec'22 Engenharia Biomédica - Jornadas Tecnológicas Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2021/11/01 - 2021/11/04	2021 Web Summit- The world's largest technology conference Congresso	Web Summit 2021 Startup Portugal, Portugal
2021/03/17 - 2021/03/17	Human platelet lysates based hydrogels as 3D platforms for tissue engineering and disease modelling applications Simpósio	2nd Aveiro-Osaka Symposium Universidade de Aveiro, Portugal
2019/10/21 - 2019/10/21	3rd Training School on Bioinspired Adhesive Hydrogels and Polymers Oficina (workshop)	COST Action- 3rd Training School on Bioinspired Adhesive Hydrogels and Polymers Universidade de Aveiro CICECO, Portugal
2018/07/02 - 2018/07/04	Ciência 2018 - Encontro com a Ciência e Tecnologia em Portugal Encontro	Ciência 2018 - Encontro com a Ciência e Tecnologia em Portugal Fundação para a Ciência e a Tecnologia, Portugal Agência Nacional de Cultura Científica, Portugal

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2021/02/26	Hydrogels derived from human chorionic membrane as an innovative platform for 3D cell culture Orientador	Elisa Alexandra Gonçalves Martins (Mestrado) Universidade de Aveiro, Portugal
2021/02/25	Taking advantage of 3D humanized in vitro models to study pulmonary diseases Orientador	Francisca Rodrigues da Piedade (Mestrado) Universidade de Aveiro, Portugal
2021/02/19	Removal of albumin from platelet lysates for the fabrication of hydrogels for 3D cell culture Orientador	Ana Miguel da Silva Loureiro (Mestrado) Universidade de Aveiro, Portugal
2019/07/16	Hidrogéis bioativos com superfície micropadronizada Arguente principal	Pedro Cruz Ribeiro Vilares (Mestrado) Universidade de Aveiro Departamento de Física, Portugal
2018/07	Physicochemical characterization of a bioactive and bioadhesive nanocomposite hydrogel Arguente principal	Raquel Maria da Costa Gonçalves (Outro) Universidade de Aveiro Departamento de Química, Portugal
2017/12	Platelet lysates loaded laminarin microparticles for cell attachment and expansion Orientador	Cláudia Isabel Rodrigues Martins (Mestrado) Universidade de Aveiro Departamento de Química, Portugal
2016	Enzymatic degradation of natural polysacharide-based layer-by-layer devices Arguente principal	Matias Joaquin Cardoso (Mestrado) Universidade do Minho, Portugal

Arbitragem científica em conferência

	Nome da conferência	Local da conferência
2016/03 - 2016/06	5th Portuguese Young Chemists Meeting (5th PYCheM) and 1st European Young Chemists Meeting (1st EYCheM), April 2016 - Guimarães, Portugal.	Guimarães

Arbitragem científica em revista

	Nome da revista (ISSN)	Editora
2021/04 - Atual	Materials Today Communications (2352-4928)	Elsevier
2020/12 - Atual	Advanced NanoBiomed Research (2699-9307)	John Wiley & Sons
2020 - Atual	Tissue Engineering (1076-3279)	Mary Ann Liebert
2018/07 - Atual	Biotechnology Progress (1520-6033)	John Wiley & Sons
2018/06 - Atual	Nanomaterials (2079-4991)	MDPI
2017/01 - Atual	ACS Biomaterials Science & Engineering (2373-9878)	American Chemical Society
2017 - Atual	Applied Surface Science (0169-4332)	Elsevier
2017 - Atual	Gels (2310-2861)	MDPI AG
2016/09 - Atual	Acta Biomaterialia (1742-7061)	Elsevier

Comissão de avaliação

	Descrição da atividade Tipo de assessoria	Instituição / Organização	Entidade financiadora
2020/10/16 - Atual	Latvian Council of Science-ACT ON COMMISSIONING OF THE WORK Avaliador	Latvijas Zinatnes Padome, Letónia
2021/11/04 - 2021/12	Evaluation of the Marie Sklodowska-Curie Postdoctoral Fellowships (PF) 2021 Call proposals. Avaliador	EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions, Bélgica European Commission Marie Sklodowska-Curie Actions, Bélgica	EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions

Consultoria / Parecer

	Descrição da atividade	Instituição / Organização
2017/01 - 2019/06	Preparation of a proposal for a new PhD Program in Biotechnology at University of Aveiro (2017). The proposal was approved in 2018 by the A3ES- Agência de Avaliação e Acreditação do Ensino Superior.	Universidade de Aveiro, Portugal

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2021/03 - Atual	Laboratório Q1	(Licenciatura)	Universidade de Aveiro, Portugal Universidade de Aveiro Departamento de Química, Portugal
2020/01/09 - Atual	Biochemistry and Biophysics	Licenciatura em Enfermagem (Licenciatura)	Universidade de Aveiro, Portugal Universidade de Aveiro Departamento de Química, Portugal
2019/10/31 - Atual	Natural-based hydrogels in bioengineering	(Outros)	Universidade de Aveiro Departamento de Química, Portugal
2019/10 - 2019/10	Processing of Biomaterials - Hydrogels	3rd Training School on Bioinspired Adhesive Hydrogels and Polymers - ENBA (Outros)	Universidade de Aveiro CICECO, Portugal Universidade de Aveiro Departamento de Química, Portugal
2017 - 2018	Cells and Tissue Engineering: Advanced hydrogel technologies to address key challenges in tissue engineering	Master in Biotechnology (Mestrado integrado)	Universidade de Aveiro Departamento de Química, Portugal
2016 - 2017	Cells and Tissue Engineering: Engineering complex hydrogels and microfabrication	Master in Biotechnology (Mestrado integrado)	Universidade de Aveiro Departamento de Química, Portugal
2016 - 2017	Macromolecular Chemistry	Master in Biotechnology (Mestrado)	Universidade de Aveiro Departamento de Química, Portugal

Membro de associação

	Nome da associação	Tipo de participação
2022/02 - Atual	Sociedade Portuguesa de Diabetologia (SPD)
2021/10 - Atual	Tissue Engineering and Regenerative Medicine International Society, Inc. (TERMIS)
2018/07 - Atual	European Association for Cancer Research - EACR
2016/01 - Atual	Sociedade Portuguesa de Química
2016 - 2018	Young Chemists Group - SPQ	Board Member

Membro de comissão

	Descrição da atividade Tipo de participação	Instituição / Organização
2022/05 - Atual	European Female Founders The European Female Founders is on a mission to inspire, encourage and build a new path for female founders. Membro

Outro júri / avaliação

	Descrição da atividade	Instituição / Organização
2019/09 - 2019/09	Monography evaluation: "Liquefied capsules containing nanogrooved microdiscs and co-encapsulated endothelial and mesenchymal stem cells for bone tissue engineering”, Master student in Biotechnology, Mariana da Silva Carreira.	Universidade de Aveiro Departamento de Química, Portugal
2019/07 - 2019/07	Monography evaluation: "Development of Advanced Decellularized-Matrix Based Breast Cancer 3D In Vitro Models for Immunotherapeutic Screening" - Luís Pedro Correia Pinto Ferreira, Master student in Biochemistry.	Universidade de Aveiro Departamento de Química, Portugal

Distinções

Prémio

2022	Women TechEU Supporting deep-tech start-ups led by women European Innovation Council, Bélgica
2020	Bluepharma \| University of Coimbra Innovation Award 2019 Bluepharma, Portugal Universidade de Coimbra, Portugal
2018	Empreende + "Technological Entrepreneurship" NOE – Noroeste Empreendedor and Unidade de Transferência de Tecnologia (UATEC), Portugal
2017	PROT IERA - contest for the materialization of business ideas
2012	Young Investigator Travel Award - 3rd TERMIS World Congress TERMIS-SYIS - Tissue Engineering and Regenerative Medicine International Society, Áustria
2011	Best Student Poster Prize - The Biointerphases Second Prize for the Best Student Poster at the European Congress and Exhibition on Advanced Materials and Processes

Outra distinção

2025	Recognized in Ciência Viva's "Mulheres na Ciência" initiative (5th volume, 2025), featuring over 100 Portuguese women scientists for contributions to biotechnology and tissue engineering. Ciência Viva, Portugal
2024	Shortlisted for the Lush Prize 2024 LUSH Glasgow City, Reino Unido
2022	Selected to participate in this edition of HiTech 2022 HiSeedTech, Portugal
2021	Finalist of the Amyris Innovation BIG Impact Award Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal Amyris Inc, Estados Unidos
2020	Assistant Researcher (Stimulus of Scientific Employment, Individual Support (CEECIND) - 3rd Edition) Fundação para a Ciência e a Tecnologia, Portugal
2013	Registration Awards - 8th International Annual Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC) Portuguese Society for Stem Cells and Cell Therapies-SPCE-TC, Portugal