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Pedro Mendes Ferreira. Concluiu o(a) Doutoramento em Ciências Cardiovasculares em 2017/05/09 pelo(a) Universidade do Porto Faculdade de Medicina, Mestrado em Fisiopatologia Cardiovascular em 2012/12/27 pelo(a) Universidade do Porto Faculdade de Medicina e Licenciatura em Biologia em 2010/07/02 pelo(a) Universidade do Porto Faculdade de Ciências. É Laboratory Animal Sciences (LAS) assistant tutor no(a) Universidade do Porto, Assistant tutor at the Cardiovascular Sciences PhD programme no(a) Universidade do Porto Faculdade de Medicina e Assistant tutor at the Cardiovascular Pathophysiology Master Programme no(a) Universidade do Porto Faculdade de Medicina. Publicou 11 artigos em revistas especializadas. Recebeu 16 prémio(s) e/ou homenagens.
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Identification

Personal identification

Full name
Pedro Mendes Ferreira

Citation names

  • Mendes-Ferreira, Pedro

Author identifiers

Ciência ID
091B-9DCD-698D
ORCID iD
0000-0003-3616-6785

Email addresses

  • pedmendesferreira@gmail.com (Personal)

Telephones

Telephone
  • 220426806 (Professional)

Knowledge fields

  • Medical and Health Sciences - Clinical Medicine - Cardiac and Cardiovascular Systems
  • Medical and Health Sciences - Basic Medicine - Physiology
  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy

Languages

Language Speaking Reading Writing Listening Peer-review
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2017/10/01 - 2019/03/31
Concluded
 European Respiratory Society Long-Term Research Fellowship (Pós-doutoramento)
Major in Pneumologia
Katholieke Universiteit Leuven Groep Biomedische Wetenschappen, Belgium
2012/09/03 - 2017/05/09
Concluded
 Ciências Cardiovasculares (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
"Neuregulin-1 role in Pulmonary Arterial Hypertension and Right Ventricular Failure" (THESIS/DISSERTATION)
 Aprovado com Distinção
2010/09/06 - 2012/12/27
Concluded
 Fisiopatologia Cardiovascular (Mestrado)
Universidade do Porto Faculdade de Medicina, Portugal
"Pathophysiological Role and Therapeutic Potential of Neuregulin-1 in Pulmonary Arterial Hypertension" (THESIS/DISSERTATION)
 19
2011/06/16 - 2011/07/08
Concluded
 Certification in Laboratory Animal Sciences (LAS) - Category C (according to FELASA recomendations) (Diploma de especialização)
Universidade do Porto, Portugal
2007/09/03 - 2010/07/02
Concluded
 Biologia (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Characterization of free-soluble BAMPs released by Aggregatibacter actinomycetemcomitans biofilms" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2020/05/01 - Current Researcher (Research) Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
2019/07/01 - 2020/04/30 Postdoc (Research) Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
2017/10/01 - 2019/05/31 Postdoc (Research) European Respiratory Society, Switzerland
Katholieke Universiteit Leuven Groep Biomedische Wetenschappen, Belgium
2015/12/01 - 2016/03/30 Visiting Researcher (Research) Institut universitaire de cardiologie et de pneumologie de Québec, Canada
2010 - 2013 Researcher (Research) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
2012/03/05 - 2012/03/24 Visiting Researcher (Research) Universiteit Antwerpen Departement Farmaceutische Wetenschappen, Belgium

Teaching in Higher Education

Category
Host institution 		Employer
2013/09/01 - 2017 Tutor (University Teacher) Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Faculdade de Medicina, Portugal
2010/03/01 - 2013/06/30 Invited Assistant (Polytechnic Teacher) Escola Superior de Enfermagem de Santa Maria, Portugal
Escola Superior de Enfermagem de Santa Maria, Portugal

Others

Category
Host institution 		Employer
2013/06/01 - 2017/05/31 PhD Scholarship - SFRH-BD-877142012 Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
2012/06/25 - 2015/06/01 Laboratory Animal Sciences (LAS) Assistant Tutor Universidade do Porto, Portugal
2012/01/02 - 2013/05/31 Research Scholarship - Pest-C/SAU/UI0051/2011 Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
2010/11/01 - 2011/11/01 Research Scholarship - PTDC/SAU-FCF/100442/2008 Universidade do Porto Faculdade de Medicina, Portugal
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
Projects

Grant

Designation Funders
2023/01/01 - Current REMODELLING OF THE INFARCTED HEART: PIEZOELECTRIC MULTIFUNCTIONAL PATCH ENABLING THE SEQUENTIAL RELEASE OF THERAPEUTIC FACTORS
101091852
Researcher
Universidade do Porto Faculdade de Medicina, Portugal
 European Union
Ongoing
2020/12/01 - Current Endothelial dysfunction as a target in chronic thromboembolic pulmonary hypertension and Covid-19
HR21-00819
Researcher
Institut d'Investigacions Biomèdiques August Pi i Sunyer, Spain
Ongoing
2020/05/01 - Current SEquential Cardiac REsynchronization Therapy (SECRET)
LCF/PR/HP17/52190002
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - Current Right ventricular adaptation under BMPR2 mutations
3PH
Principal investigator
INSERM UMRS 939, France

Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
2019/07/01 - Current Novos alvos na insuficiência diastólica: das comorbilidades à medicina personalizada - NETDIAMOND
SAICT-PAC/0047/2015
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2020/06/23 - Current Pathophysiological role of vitamin D and microbiota in pulmonary hypertension and erectile dysfunction (VIMIPHED)
PID2019-107363RB-I00
Researcher
Universidad Complutense de Madrid, Spain
 Gobierno de España Ministerio de Ciencia e Innovación
Ongoing
2019/07/01 - Current Sequential eletrical pacing for resynchronization therapy – SexPeRT
PTDC/BTM-SAL/32616/2017 / POCI-01-0145-FEDER-032616
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/06/01 - Current TRAIN-HEART
info:eu-repo/grantAgreement/EC/H2020/813716/EU
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 European Commission
Ongoing
2018/09/01 - Current Role of microvascular rarefaction in Heart Failure with Preserved Ejection Fraction
FWO-1160718N / ERA-CV-LYMIT-DIS
Researcher
Katholieke Universiteit Leuven Centrum voor Moleculaire en Vasculaire Biologie, Belgium
 Fonds Wetenschappelijk Onderzoek Vlaanderen

European Union
Ongoing
2018/04/06 - Current IMPAcT - Insight in the pathophysiological role of Mir-146a in Pulmonary Arterial hypertension - Therapeutic implications
PTDC/MED-FSL/31719/2017
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2016/09/01 - Current Role of Urocortin-2 in preventing and treating doxorubicin-induced cardiotoxicity
U&D nº51/94
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular
Ongoing
2013/07/01 - Current Pathophysiological role and therapeutic potential of urocortin 2 in pulmonary hypertension
PTDC/DTP-FTO/0130/2012
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2010/06/01 - Current Role of the neuregulin system in pulmonary arterial hypertension - pathophysiological and therapeutic implications
PTDC/SAU-FCF/100442/2008
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2021/01/01 - 2025/12/31 Rede de Investigação em Saúde: do Laboratório à Saúde Comunitária
LA/P/0053/2020
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Universidade do Algarve, Portugal

Universidade da Madeira, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Universidade de Lisboa Centro Cardiovascular da Universidade de Lisboa, Portugal

Centro de Investigação em Tecnologias e Serviços de Saúde, Portugal

Universidade do Porto Faculdade de Medicina, Portugal

Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal

Escola Superior de Enfermagem do Porto, Portugal

Universidade de Aveiro, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2021/01/01 - 2025/12/31 Health Research Network: From Lab to Community Health
10.54499/LA/P/0053/2020
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal

Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Universidade do Algarve, Portugal

Universidade da Madeira, Portugal

Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal

Universidade de Lisboa Centro Cardiovascular da Universidade de Lisboa, Portugal

Universidade Nova de Lisboa, Portugal

Centro de Investigação em Tecnologias e Serviços de Saúde, Portugal

Universidade de Aveiro, Portugal

Associação para a Investigação e Desenvolvimento da Faculdade de Medicina, Portugal

Escola Superior de Enfermagem do Porto, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/03/12 - 2024/09/11 Relaxin-2 and Pulmonary Arterial Hypertension: pathophysiological role and therapeutic potential
2022.08921.PTDC
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2018/07/01 - 2021/06/30 Compreensão do papel fisiopatológico do miR-146a na hipertensão arterial pulmonar - implicações terapêuticas
PTDC/MED-FSL/31719/2017
Universidade do Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2019/01/01 - 2019/12/31 Unidade de Investigação e Desenvolvimento Cardiovascular
UID/IC/00051/2019
Universidade do Porto Faculdade de Medicina, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2017/10/01 - 2019/05/01 ß-3 adrenoceptors: a therapeutic target for pulmonary arterial hypertension
P168/2018
Post-doc Fellow
Katholieke Universiteit Leuven Groep Biomedische Wetenschappen, Belgium
 Katholieke Universiteit Leuven
Ongoing

Other

Designation Funders
2019/11/25 - Current PORTCASTS – Porto Cardiac Simulation and Training System
PORTCASTS
Principal investigator
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
Ongoing
2019/07/01 - Current Role of miRNA-199b in a large animal model of left ventricular pressure overload
199b
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 Mirabilis Therapeutics
Ongoing
2018/09/01 - Current microCT for the non-invasive evaluation of lung disease, function and therapy
microCT
Researcher
Katholieke Universiteit Leuven Groep Biomedische Wetenschappen, Belgium
2018/03/01 - Current Possible pathophysiological role of vitamin D deficit in pulmonary arterial hypertension
Vitamin-D
Researcher
Universidad Complutense de Madrid Departamento de Farmacología, Spain
Ongoing
2016/09/01 - Current Pre-clinical testing of GGF2 in Right Ventricle Pressure Overload
GGF2
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 Acorda Therapeutics Inc
Ongoing
2016/03/01 - Current Understanding of the downstream consequences of the genetic risk factors of PAH (KCNK3 and BMPR2 gene mutations) on the pulmonary vasculature and right ventricle,
N/A
Researcher
INSERM U999, France
2015/09/01 - Current Pre-clinical testing of NTP42 in Pulmonary Arterial Hypertension
NTP42
Researcher
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
 ATXA Therapeutics
Ongoing
2012/09/01 - 2014/09/01 Modulation of antiotensin-II vasoconstriction by angiotensin 1-7 in human thoracic arteries from patients submited to coronary artery bypass graft surgery
Delta Prize in Ischemic Cardiomyopathy 2012/13
Sociedade Portuguesa de Cardiologia, Portugal
 Sociedade Portuguesa de Cardiologia
Concluded
Outputs

Publications

Book chapter
  1. Adao, Rui; Maia-Rocha, Carolina; Santos-Ribeiro, Diana; Mendes- Ferreira, Pedro; Leite-Moreira, Adelino F.; Bras-Silva, Carmen. "Cardiotoxicity of Cancer Chemotherapy–Recent Developments". In Frontiers in Drug Design & Discovery, 36-83. BENTHAM SCIENCE PUBLISHERS, 2016.
    10.2174/9781681081656116070004
Conference abstract
  1. Moreira-Costa, Liliana; Leite-Moreira, André M; Adão, Rui; Miranda, Isabel; Cerqueira, Rui; Perros, Frederic; Leite-Moreira, Adelino F; Lourenço, André P; Mendes-Ferreira, Pedro. "Size does matter: a simple swine model of chronic pulmonary hypertension". 2023.
    10.1183/13993003.congress-2023.pa440
  2. Quarck, Rozenn; Wagenaar, Allard; Tielemans, Birger; Mendes-Ferreira, Pedro; Perros, Frédéric; Dorfmuller, Peter; Belge, Catharina; Delcroix, Marion. "Repeated embolization with blood clots containing an inhibitor of angiogenesis induces chronic thromboembolic pulmonary hypertension in rabbits". Paper presented in Pulmonary Vascular Research Institute, 2019.
  3. Miranda, Sónia; Mendes-Ferreira, Pedro; Adão, Rui; Maia-Rocha, Carolina; Santos-Ribeiro, Diana; Pimentel, Luís; Monteiro-Pinto, Cláudia; et al. "MicroRNA-146a role in the pathophysiology of Pulmonary Arterial Hypertension". Paper presented in SPCCTV Congress, 2019.
    Published
  4. Mendes-Ferreira, Pedro; Adão, Rui; Leite-Moreira, Adelino; Brás-Silva, Carmen; Belge, Catharina. "ß-3 adrenoceptors: a therapeutic target for Pulmonary Arterial Hypertension". Paper presented in SPCCTV Congress, 2019.
    Published
  5. Quarck, Rozenn; Wagenaar, Allard; Tielemans, Birger; Mendes-Ferreira, Pedro; Perros, Frederic; Dorfmuller, Peter; Belge, Catharina; Delcroix, Marion. "Local inhibition of angiogenesis combined with repeated blood clot embolization induces chronic thromboembolic pulmonary hypertension in rabbits". 2018.
    10.1183/13993003.congress-2018.oa4947
  6. Adão, Rui; Mendes-Ferreira, Pedro; Santos-Ribeiro, Diana; Maia-Rocha, Carolina; Pimentel, Luís; Pinto, Cláudia; Mulvaney, Eamon P.; et al. "Urocortin-2 improves right ventricular function and attenuates experimental pulmonary arterial hypertension". 2018.
    10.1183/13993003.congress-2018.pa3041
  7. Mendes-Ferreira, Pedro; Adao, Rui; Quarck, Rozenn; Belge, Catharina; Delcroix, Marion; Bras-Silva, Carmen. "Activation of the Beta-3 adrenoceptor in experimental pulmonary hypertension". 2018.
    10.1183/13993003.congress-2018.pa3063
  8. Adão, Rui; Mendes-Ferreira, Pedro; Santos-Ribeiro, Diana; Maia-Rocha, Carolina; Potus, François; Breuils-Bonnet, Sandra; Provencher, Steve; et al. "Urocortin-2 improves right ventricular function in pulmonary arterial hypertension". Paper presented in American Thoracic Society Conference, 2016.
    Published
  9. Mendes-Ferreira, Pedro; Potus, François; Santos-Ribeiro, Diana; Maia-Rocha, Carolina; Adão, Rui; Leite-Moreira, Adelino; Provencher, Steve; Bonnet, Sébastien; Brás-Silva, Carmen. "Microrna-146a expression is increased in human PAH". Paper presented in American Thoracic Society Conference, 2016.
    Published
  10. Adão, Rui; Mendes-Ferreira, Pedro; Maia-Rocha, Carolina; Santos-Ribeiro, Diana; Potus, François; Breuils-Bonnet, Sandra; Provencher, Steve; et al. "Urocortin-2treatment reduces right ventricular dysfunction in pulmonary arterial hypertension". Paper presented in European Society of Cardiology Congress, 2016.
    Published
  11. Mendes-Ferreira, Pedro; Santos-Ribeiro, Diana; Adão, Rui; Maia-Rocha, Carolina; Mendes-Ferreira, Miguel; Sousa-Mendes, Cláudia; Leite-Moreira, Adelino; Brás-Silva, Carmen. "Pulmonary artery banding-induced adaptive and maladaptive remodelling of the right ventricle in the rat". Paper presented in Heart Failure Congress - European Society of Cardiology, 2016.
    Published
  12. Santos-Ribeiro, Diana; Adão, Rui; Maia-Rocha, Carolina; Alves, Bárbara; Mendes-Ferreira, Pedro; Leite-Moreira, Adelino; Brás-Silva, Carmen. "Urocortin-2 Improves Right Ventricular Function in Pulmonary Arterial Hypertension". Paper presented in American Heart Association's Scientific Sessions, 2014.
    Published
  13. Adão, Rui; Mendes-Ferreira, Pedro; Maia-Rocha, Carolina; Lourenço, André; Falcão-Pires, Inês; De Keulenaer, Gilles; Leite-Moreira, Adelino; Brás-Silva, Carmen. "Neuregulin-1 Chronic Treatment Improves Right Ventricle Cardiomyocyte Function in Pulmonary Hypertension". Paper presented in American Heart Association's Scientific Sessions, 2013.
    Published
Conference poster
  1. Moreira-Costa, Liliana; Leite-Moreira, André; Adão, Rui; Miranda, Isabel; Cerqueira, RJ; Perros, Frédéric; ADELINO F. LEITE-MOREIRA; Lourenço, André; Mendes-Ferreira, Pedro. "Indução de um modelo de hipertensão pulmonar crónica em suínos pela embolização de suturas". Paper presented in 39th Pneumology Congress, 2023.
  2. Silva, Maria; Mendes-Ferreira, Pedro; Adão, R; Maia-Rocha C; Lourenco, AP; Leite-Moreira AF; Bras-Silva, C. "Neuregulin attenuates right ventricular hypertrophy and dysfunction in an experimental model of pulmonary hypertension". Paper presented in IJUP¿ 11 ¿ 4th Meeting of Young Researchers at the University of Porto, 2011.
Journal article
  1. Mendes-Ferreira, Pedro; Leite-Moreira, André M.; Leite-Moreira, Adelino F.. "Reverse Translation of Pericardial Access". JACC: Basic to Translational Science 9 10 (2024): 1248-1249. https://doi.org/10.1016/j.jacbts.2024.08.007.
    10.1016/j.jacbts.2024.08.007
  2. Mendes-Ferreira, Pedro; Leite-Moreira, Adelino F.. "Doxorubicin-induced cardiotoxicity – Are plants the answer?". Revista Portuguesa de Cardiologia (2024): https://doi.org/10.1016/j.repc.2024.10.003.
    10.1016/j.repc.2024.10.003
  3. Santos-Gomes, Joana; Mendes-Ferreira, Pedro; Adão, Rui; Maia-Rocha, Carolina; Rego, Beatriz; Poels, Manu; Saint-Martin Willer, Anaïs; et al. "Unraveling the Impact of miR-146a in Pulmonary Arterial Hypertension Pathophysiology and Right Ventricular Function". International Journal of Molecular Sciences 25 15 (2024): 8054. https://doi.org/10.3390/ijms25158054.
    10.3390/ijms25158054
  4. Alban Todesco; Julien Grynblat; Kouamé Kan Firmin Akoumia; Damien Bonnet; Pedro Mendes-Ferreira; Stéphane Morisset; Denis Chemla; et al. "Pulmonary Hypertension Induced by Right Pulmonary Artery Occlusion: Hemodynamic Consequences of Bmpr2 Mutation". Journal of the American Heart Association (2024): https://doi.org/10.1161/JAHA.124.034621.
    10.1161/JAHA.124.034621
  5. Cerqueira, Rui; Moreira-Costa, Liliana; Beslika, Evangelia; Leite-Moreira, André; Silva, Joana; da Costa Martins, Paula A.; Leite-Moreira, Adelino; Lourenço, André; Mendes-Ferreira, Pedro. "A Minimally Invasive Model of Aortic Stenosis in Swine". Journal of Visualized Experiments 200 (2023): http://dx.doi.org/10.3791/65780.
    10.3791/65780
  6. Raposo, Luís; Cerqueira, Rui J.; Leite, Sara; Moreira-Costa, Liliana; Laundos, Tiago L.; Miranda, Joana O.; Mendes-Ferreira, Pedro; et al. "Human-umbilical cord matrix mesenchymal cells improved left ventricular contractility independently of infarct size in swine myocardial infarction with reperfusion". Frontiers in Cardiovascular Medicine 10 (2023): http://dx.doi.org/10.3389/fcvm.2023.1186574.
    10.3389/fcvm.2023.1186574
  7. Mulvaney, Eamon P.; Renzo, Fabiana; Adão, Rui; Dupre, Emilie; Bialesova, Lucia; Salvatore, Viviana; Reid, Helen M.; et al. "The thromboxane receptor antagonist NTP42 promotes beneficial adaptation and preserves cardiac function in experimental models of right heart overload". Frontiers in Cardiovascular Medicine 9 (2022): http://dx.doi.org/10.3389/fcvm.2022.1063967.
    10.3389/fcvm.2022.1063967
  8. Raquel F Videira; Anne Marie C Koop; Lara Ottaviani; Ella M Poels; Jordy M M Kocken; Cristobal Dos Remedios; Pedro Mendes-Ferreira; et al. "The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload". Cardiovascular Research (2022): https://doi.org/10.1093/cvr/cvab299.
    10.1093/cvr/cvab299
  9. Olivencia, Miguel A.; Esquivel-Ruiz, Sergio; Callejo, María; Mondéjar-Parreño, Gema; Quintana-Villamandos, Begoña; Barreira, Bianca; Sacedón, Rosa; et al. "Cardiac and Pulmonary Vascular Dysfunction in Vitamin Deficient Bmpr2 Mutant Rats". American Journal of Respiratory Cell and Molecular Biology 67 3 (2022): 402-405. http://dx.doi.org/10.1165/rcmb.2022-0001le.
    10.1165/rcmb.2022-0001le
  10. Marceau Quatredeniers; Pedro Mendes-Ferreira; Diana Santos-Ribeiro; Morad K. Nakhleh; Maria-Rosa Ghigna; Sylvia Cohen-Kaminsky; Frédéric Perros. "Iron Deficiency in Pulmonary Arterial Hypertension: A Deep Dive into the Mechanisms". Cells 10 2 (2021): 477-477. https://doi.org/10.3390/cells10020477.
    10.3390/cells10020477
  11. Lambert, Mélanie; Mendes-Ferreira, Pedro; Ghigna, Maria-Rosa; LeRibeuz, Hélène; Adão, Rui; Boet, Angèle; Capuano, Véronique; et al. "Kcnk3 dysfunction exaggerates the development of pulmonary hypertension induced by left ventricular pressure overload". Cardiovascular Research (2021): http://dx.doi.org/10.1093/cvr/cvab016.
    10.1093/cvr/cvab016
  12. Cuijpers, Ilona; Carai, Paolo; Mendes-Ferreira, Pedro; Simmonds, Steven J.; Mulder, Paul; Miranda-Silva, Daniela; De Giorgio, Daria; et al. "The effect of different anaesthetics on echocardiographic evaluation of diastolic dysfunction in a heart failure with preserved ejection fraction model". Scientific Reports 10 1 (2020): http://dx.doi.org/10.1038/s41598-020-72924-5.
    10.1038/s41598-020-72924-5
  13. Mendes-Ferreira, Pedro; Adão, Rui; Miranda, Alice; Leite-Moreira, Adelino F.; Brás-Silva, Carmen. "Comprehensive cardiovascular function analysis in rodents with right heart failure". Journal of Visualized Experiments (2020):
    Under revision
  14. Mulvaney, Eamon; Reid, Helen M.; Bialesova, Lucia; Mendes-Ferreira, Pedro; Adão, Rui; Brás-Silva, Carmen; Kinsella, B. Therese. "Efficacy of the thromboxane receptor antagonist NTP42 alone, or in combination with Sildenafil, in the Sugen/hypoxia-induced model of NTP42". European Journal of Pharmacology (2020):
    Submitted
  15. Mendes-Ferreira, Pedro; Manaud, Grégoire; Perros, Frédéric. "Response by Mendes-Ferreira et al to Letter Regarding Article, "Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension"". Circulation 140 7 (2019): http://dx.doi.org/10.1161/circulationaha.119.041480.
    Published • 10.1161/circulationaha.119.041480
  16. Rui Adão; Pedro Mendes-Ferreira; Carolina Maia-Rocha; Diana Santos-Ribeiro; Patrícia Gonçalves Rodrigues; André Vidal-Meireles; Cláudia Monteiro-Pinto; et al. "Neuregulin-1 attenuates right ventricular diastolic stiffness in experimental pulmonary hypertension". Clinical and Experimental Pharmacology and Physiology (2019): https://doi.org/10.1111/1440-1681.13043.
    10.1111/1440-1681.13043
  17. Hautefort, Aurélie; Mendes-Ferreira, Pedro; Sabourin, Jessica; Manaud, Grégoire; Bertero, Thomas; Rucker-Martin, Catherine; Riou, Marianne; et al. "Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension". Circulation 139 7 (2019): 932-948. http://dx.doi.org/10.1161/circulationaha.118.033744.
    Published • 10.1161/circulationaha.118.033744
  18. Adão, Rui; Kraler, Simon; Abdellatif, Mahmoud; Pinto, Ana Rita; Mendes-Ferreira, Pedro; Ljubojevic-Holzer, S; Leite-Moreira, Adelino; Sedej, Simon; Brás-Silva, Carmen. "Acute and chronic effects of urocortin-2 therapy on intracellular Ca2+ homeostasis in right heart failure induced by pulmonary arterial hypertension". Scientific Reports (2019):
    Under revision
  19. Lambert M; Boet A; Rucker-Martin C; Mendes-Ferreira P; Capuano V; Hatem S; Adão R; et al. "Loss of KCNK3 is a hallmark of RV hypertrophy/dysfunction associated with pulmonary hypertension.". Cardiovascular research (2018): http://europepmc.org/abstract/med/29360952.
    10.1093/cvr/cvy016
  20. Adão, R.; Mendes-Ferreira, P.; Santos-Ribeiro, D.; Maia-Rocha, C.; Pimentel, L.D.; Monteiro-Pinto, C.; Mulvaney, E.P.; et al. "Urocortin-2 improves right ventricular function and attenuates pulmonary arterial hypertension". Cardiovascular Research 114 8 (2018): 1165-1177. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050947222&partnerID=MN8TOARS.
    10.1093/cvr/cvy076
  21. Guerra M; Mendes-Ferreira P; Adão R; Pereira E; Vieira M; Lourenço AP; Brás-Silva C; et al. "Improvement in left intraventricular pressure gradients after aortic valve replacement in aortic stenosis patients.". Experimental physiology (2017): http://europepmc.org/abstract/med/28194824.
    10.1113/ep086191
  22. Santos-Ribeiro D; Mendes-Ferreira P; Maia-Rocha C; Adão R; Leite-Moreira AF; Brás-Silva C. "Pulmonary arterial hypertension: Basic knowledge for clinicians.". Archives of cardiovascular diseases (2016): http://europepmc.org/abstract/med/27595464.
    10.1016/j.acvd.2016.03.004
  23. Mendes-Ferreira P; Santos-Ribeiro D; Adão R; Maia-Rocha C; Mendes-Ferreira M; Sousa-Mendes C; Leite-Moreira AF; Brás-Silva C. "Distinct right ventricle remodeling in response to pressure overload in the rat.". American Journal of Physiology - Heart and Circulatory Physiology (2016): http://europepmc.org/abstract/med/27199115.
    10.1152/ajpheart.00089.2016
  24. Mendes-Ferreira P; Maia-Rocha C; Adão R; Mendes MJ; Santos-Ribeiro D; Alves BS; Cerqueira RJ; et al. "Neuregulin-1 improves right ventricular function and attenuates experimental pulmonary arterial hypertension.". Cardiovascular research (2016): http://europepmc.org/abstract/med/26503987.
    10.1093/cvr/cvv244
  25. Mendonça L; Mendes-Ferreira P; Bento-Leite A; Cerqueira R; Amorim MJ; Pinho P; Brás-Silva C; Leite-Moreira AF; Castro-Chaves P. "Angiotensin-(1-7) modulates angiotensin II-induced vasoconstriction in human mammary artery.". Cardiovascular Drugs and Therapy (2014): http://europepmc.org/abstract/med/25301384.
    10.1007/s10557-014-6555-4
  26. Fontoura D; Oliveira-Pinto J; Tavares-Silva M; Leite S; Vasques-Nóvoa F; Mendes-Ferreira P; Lourenço AP; Leite-Moreira AF. "Myocardial and anti-inflammatory effects of chronic bosentan therapy in monocrotaline-induced pulmonary hypertension.". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology (2014): http://europepmc.org/abstract/med/24780128.
    10.1016/j.repc.2013.09.016
  27. Mendes-Ferreira, P.; De Keulenaer, G.W.; Leite-Moreira, A.F.; Brás-Silva, C.. "Therapeutic potential of neuregulin-1 in cardiovascular disease". Drug Discovery Today 18 17-18 (2013): 836-842. http://www.scopus.com/inward/record.url?eid=2-s2.0-84883242344&partnerID=MN8TOARS.
    10.1016/j.drudis.2013.01.010
  28. Lopes-Conceição L; Dias-Neto M; Fontes-Sousa AP; Mendes-Ferreira P; Maia-Rocha C; Henriques-Coelho T; de Keulenaer G; Leite Moreira AF; Brás-Silva C. "[Neuregulin1/ErbB system: importance in the control of cardiovascular function].". Acta medica portuguesa (2011): http://europepmc.org/abstract/med/22863512.
  29. Lopes-Conceição, L.; Dias-Neto, M.; Fontes-Sousa, A.P.; Mendes-Ferreira, P.; Maia-Rocha, C.; Henriquescoelho, T.; de Keulenaer, G.; Leite Moreira, A.F.; Brás-Silva, C.. "Neuregulin1/ErbB system: Importance in the control of cardiovascular function,Sistema neuregulina1/ErbB: Importância no controlo da função cardíaca". Acta Medica Portuguesa 24 SUPPL.4 (2011): 1009-1020. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864244767&partnerID=MN8TOARS.

Other

Other output
  1. Prototype testing for ADinstruments and Millar. Testing of new protoptypes of experimental grade pressure-volume catheters and clinical grade right heart catheterization catheters using solid-state high fidelity pressure sensors.. 2020. Mendes-Ferreira, Pedro.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/06/28 Measurement of Cardiac Function Using Pressure-Volume Loops in Swine Webinar
Inside Scientific
2021/11/30 Pressure-Volume recordings in small & large animals Cardiovascular Research Day
ADinstruments
2013/02/27 Neuregulin attenuates Right Ventricular and Pulmonary Endothelial Dysfunction in an Experimental Model of Pulmonary Hypertension 5th World Symposium on Pulmonary Hypertension
Wold Symposia on Pulmonary Hypertension Association (Nice, France)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/10/21 - 2024 The effect of miR-106b overexpression in a large animal model after induced myocardial infarction
Co-supervisor of Evangelia Beslika
 Doctoral Programm in Cardiovascular Sciences (PhD)
Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2013/04/10 - Current Pressure-Volume Loop Analysis Workshop organized by ADinstruments & Millar (2013/04/10)
Workshop (Co-organisor)
 Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
2025/01/28 - 2025/01/29 Pressure-Volume Loop User Group Meeting (2025/01/28 - 2025/01/29)
Meeting (Co-organisor)
 Universidade do Porto Faculdade de Medicina, Portugal
2020/05/19 - 2020/05/20 IberoHeart - Cardiac Surgery Training Sessions (2020/05/19 - 2020/05/20)
Workshop (Member of the Organising Committee)
 CTF-XXIAC, Spain
2020/04/24 - 2020/04/24 Pressure-Volume Loop in Large Animals Workshop (ADinstruments) (2020/04/24 - 2020/04/24)
Workshop (Co-organisor)
 Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2020/03/16 - 2020/03/21 Apresentação Tecnológica do Sistema Cirúrgico da Vinci Xi
Workshop
 Apresentação Tecnológica do Sistema Cirúrgico da Vinci Xi
Universidade do Porto Faculdade de Medicina, Portugal
2020/03/05 - 2020/03/08 European Respiratory Society - Lung Science Conference
Conference
 European Respiratory Society - Lung Science Conference
European Respiratory Society, Switzerland
2018/05/18 - 2018/05/18 Pressure-Volume Loop European User Group Meeting
Conference
 Pressure-Volume Loop European User Group Meeting
INSERM U999, France
2018/02/27 - 2018/03/01 6th World Symposium on Pulmonary Hypertension
Symposium
 6th World Symposium on Pulmonary Hypertension
World Symposia on Pulmonary Hypertension Association, France
2018 - 2018 Data Sciences Internation (DSI) User Group Meeting
Workshop
 Telemetry implantation training and User Group Meeting
Katholieke Universiteit Leuven, Belgium
2017/10/05 - 2017/10/06 5th Scientific seminar on Pulmonary Hypertension – sponsored by GlaxoSmithKline
Symposium
 Connecting expertise in a rare disease in 2017
Katholieke Universiteit Leuven, Belgium
2016/10/27 - 2016/10/28 European Respiratory Society (ERS) Research Seminar
Seminar
 Pulmonary vascular endothelium: orchestra conductor in respiratory diseases - highlights from basic research to therapy
Université Paris-Sud Bibliothèque Universitaire Kremlin-Bicêtre, France
2013 - 2013 ESC Summer School
Symposium
 ESC Summer School
Société Européenne de Cardiologie, France

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2020/05/25 Sudden cardiac arrest: can automatic external defibrillators really help?
President of the jury
 Estela Rafaela Moreira Magalhães Carvalho de Sousa (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2020/05/11 The Role of NETs in the Thrombotic Phenotype of Pulmonary Arterial Hypertension
(Thesis) Main arguer
 Luís Pedro Baptista Barros Ribeiro Dourado (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2019/07/08 Role of microRNAs, namely miR-146a, in Pulmonary Arterial Hypertension and Right Ventricle Failure - Therapeutic Implications
(Thesis) Main arguer
 Rita Azevedo Sousa e Silva (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/01/28 Pathophysiological role of urocortin-2 system in pulmonaryn hypertension - therapeutic implications
(Thesis) Arguer
 Rui Miguel da Costa Adão (PhD)
Universidade do Porto Faculdade de Medicina, Portugal

Association member

Society Organization name Role
2016 - Current European Respiratory Society (ID: 367883) Member
2015/01/01 - Current European Society of Cardiology (ID: 467458) Member
2015 - Current Sociedade Portuguesa de Pneumologia Sócio
2013/12/30 - Current Sociedade Portuguesa de Cardiologia (ID: 2259) Sócio

Consulting

Activity description Institution / Organization
2019/04/02 - Current Consultancy and customer support for pressure-volume catheter systems ADInstruments Pty Ltd, New Zealand

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2012/06/25 - Current Laboratory Animal Sciences (LAS) REF#: 421/000/000/2013 Laboratory Animal Sciences (LAS) (Diploma de especialização) Universidade do Porto, Portugal
2020/04/24 - 2020/04/24 Curso Pré-Congresso CPC - Mitral Valve 360 (PORTCASTS - Porto Cardiac Simulation and Training System) Curso Pré-Congresso CPC - Mitral Valve 360 (Curso de Especialização Tecnológica) Sociedade Portuguesa de Cardiologia, Portugal
2012/09/01 - 2015/07/31 Pre/post-operative monitoring and follow-up in laboratory animals Laboratory Animal Sciences (LAS) accreditation course (Diploma de especialização) Universidade do Porto, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2020/03/03 - Current Scientific Reports (2045-2322) Springer Science and Business Media LLC
2018/05/07 - 2020/04/19 Revista Portuguesa de Cardiologia (0870-2551) Elsevier
2018/04/04 - 2019/02/13 Biochemical Pharmacology (0006-2952) Elsevier
Distinctions

Award

2023 Prémio Thomé Villar 2023
Sociedade Portuguesa de Pneumologia, Portugal
2019 Robalo Cordeiro Award – SPP/Novartis
Sociedade Portuguesa de Pneumologia, Portugal
2017 Thomé Villar/Boehringer Ingelheim – SPP
Sociedade Portuguesa de Pneumologia, Portugal
2017 Servier Award in Heart Failure – Basic Science
Sociedade Portuguesa de Cardiologia, Portugal
2016 Robalo Cordeiro Award – SPP/Novartis
Sociedade Portuguesa de Pneumologia, Portugal
2016 Thomé Villar/Boehringer Ingelheim – SPP
Sociedade Portuguesa de Pneumologia, Portugal
2015 Robalo Cordeiro Award – SPP/Novartis
Sociedade Portuguesa de Pneumologia, Portugal
2015 Servier award in Heart Failure – Basic Science
Sociedade Portuguesa de Cardiologia, Portugal
2015 Thomé Villar/Boehringer Ingelheim - SPP
2014 Servier Award in Heart Failure – Basic Science
Sociedade Portuguesa de Cardiologia, Portugal
2013 Delta Prize in Ischemic Cardiomyopathy 2012-13
Sociedade Portuguesa de Cardiologia, Portugal
2012 Delta Prize in Ischemic Cardiomyopathy 2011-12
Sociedade Portuguesa de Cardiologia, Portugal
2011 IJUP 2011, Projectos Pluridisciplinares UP
Universidade do Porto, Portugal

Banco Santander Totta, Portugal
2010 IJUP 2010, Projectos Pluridisciplinares UP
Universidade do Porto, Portugal

Banco Santander Totta, Portugal
2009 IJUP 2009, Projectos Pluridisciplinares UP
Universidade do Porto, Portugal

Banco Santander Totta, Portugal

Other distinction

2021 Paris - Porto Pulmonary Hypertension Collaborative Laboratory (3PH)
INSERM, France
2018 Honorable mention – 2ª Edition of Janssen Innovation Award
Janssen Pharmaceuticals Inc, United States
2017 Bolsa de Estudos João Porto 2016-2017
Sociedade Portuguesa de Cardiologia, Portugal
2014 Bolsa de Estudo João Porto 2013­-2014
Sociedade Portuguesa de Cardiologia, Portugal