Personal identification

Full name

Inês Gomes Direito

Citation names

• Direito, Inês Gomes

Author identifiers

Ciência ID

FC1C-0C0E-1095

ORCID iD

0000-0001-9188-7118

	Degree	Classification
2017/09/01 - 2023/03/16 Concluded	Doutoramento Biomedicina (Doutoramento) Universidade de Aveiro, Portugal "Loss of proteostasis in cancer and its relation with acquired resistance to endocrine therapy" (THESIS/DISSERTATION)
2015 Concluded	Biologia Molecular e Genética (Mestrado) Major in Sem especialização Universidade de Lisboa Faculdade de Ciências, Portugal "Expression of aquaporins in prancreatic tumors: new targets for cancer therapy?" (THESIS/DISSERTATION)	18 valores
2007/09/01 - 2011/09/01 Concluded	Anatomia Patológica, Citológica e Tanatológica (Licenciatura) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal	16

Science

	Category Host institution	Employer
2022/09/01 - Current	Postdoc (Research)	Instituto de Biologia Experimental e Tecnológica, Portugal
2016/05/01 - 2017/05/01	Researcher (Research)	Universidade de Aveiro Instituto de Biomedicina, Portugal

Others

	Category Host institution	Employer
2017/09/01 - 2023/03/16	PhD Student	Universidade de Aveiro Instituto de Biomedicina, Portugal
	Universidade de Aveiro Instituto de Biomedicina, Portugal
2017/06/01 - 2017/08/31	Research fellow	Universidade de Aveiro Instituto de Biomedicina, Portugal
2013/04/01 - 2014/09/30	Recepcionist	Vodafone Portugal Comunicações Pessoais SA, Portugal
2012/02/01 - 2012/12/31	Technical sales representative	ZMWay Lab Solutions, Portugal

Contract

	Designation	Funders
2020 - 2021	PREDICT- PRotein aggrEgation Detection to Indicate response to anti-Cancer Treatment PREDICT Researcher	Comissão de Coordenação e Desenvolvimento Regional do Centro Concluded
2019 - 2021	MEDISIS: Promoting the involvement of key players in the Centro Region for the transfer of knowledge and the creation of new partnerships in the area of Regenerative Medicine and Precision Medicine CENTRO-01-0246-FEDER-000018 Researcher	Comissão de Coordenação e Desenvolvimento Regional do Centro Concluded
2018 - 2020	Protein aggregation across the lifespan - pAGE CENTRO-01-0145-FEDER-000003 Researcher	Comissão de Coordenação e Desenvolvimento Regional do Centro Concluded
2019/01/01 - 2019/12	Institute for Biomedicine - Aveiro UID/BIM/04501/2019 Researcher	Concluded

Publications

Book chapter	Direito, Inês Gomes. "Hormone signalling pathways in the postnatal mammary gland". In Tissue-Specific Cell Signaling. Springuer, 2020. Accepted
Conference paper	Carolina Sousa; Inês Direito; Samuel Guieu; Paulo André; Luisa Helguero; M. Fátima Domingues; Nélia Alberto. "Smartphone-based Fluorescence System for Protein Aggregates Detection". 2023. 10.1109/enbeng58165.2023.10175370 Fátima Domingues, M.; Direito, Inês; Sousa, Carolina; Radwan, Ayman; Antunes, Paulo; André, Paulo; Helguero, Luisa; Alberto, Nélia. "Optical Fibre FPI End-Tip based Sensor for Protein Aggregation Detection". 2022. 10.1109/HealthCom54947.2022.9982774
Journal article	Monteiro FL; Góis A; Direito I; Melo T; Neves B; Alves MI; Batista I; Domingues MDR; Luisa Helguero. "Inhibiting SETD7 methyl-transferase activity impairs differentiation, lipid metabolism and lactogenesis in mammary epithelial cells.". FEBS letters (2023): https://doi.org/10.1002/1873-3468.14737. 10.1002/1873-3468.14737 Inês Direito; Daniela Gomes; Fatima Monteiro; Isa Carneiro; João Lobo; Rui Henrique; Carmen Jeronimo; Carmen Jerónimo; Luisa Helguero. "The Clinicopathological Significance of BiP/GRP-78 in Breast Cancer: A Meta-Analysis of Public Datasets and Immunohistochemical Detection". Current Oncology 29 12 (2022): 9066-9087. http://dx.doi.org/10.3390/curroncol29120710. 10.3390/curroncol29120710 Direito, Inês Gomes; Monteiro, Fátima L.; Direito, Inês; Amado, Francisco; Afreixo, Vera; Santos, Lúcio L.; Helguero, Luisa A.. "Association Between Estrogen Receptors and GATA3 in Bladder Cancer: A Systematic Review and Meta-Analysis of Their Clinicopathological Significance". Frontiers in Endocrinology 12 (2021): http://dx.doi.org/10.3389/fendo.2021.684140. 10.3389/fendo.2021.684140 Direito, Inês; Monteiro, Liliana; Melo, Tânia; Figueira, Daniela; Lobo, João; Enes, Vera; Moura, Gabriela; et al. "Protein Aggregation Patterns Inform about Breast Cancer Response to Antiestrogens and Reveal the RNA Ligase RTCB as Mediator of Acquired Tamoxifen Resistance". Cancers 13 13 (2021): 3195. http://dx.doi.org/10.3390/cancers13133195. 10.3390/cancers13133195 Direito I; Fardilha M; Helguero LA. "Contribution of the unfolded protein response to breast and prostate tissue homeostasis and its significance to cancer endocrine response.". Carcinogenesis (2018): http://europepmc.org/abstract/med/30596981. 10.1093/carcin/bgy182 Direito I; Paulino J; Vigia E; Brito MA; Soveral G. "Differential expression of aquaporin-3 and aquaporin-5 in pancreatic ductal adenocarcinoma.". (2017): http://europepmc.org/abstract/med/28471475. 10.1002/jso.24605 Direito, I.; Madeira, A.; Brito, M.A.; Soveral, G.. "Aquaporin-5: From structure to function and dysfunction in cancer". Cellular and Molecular Life Sciences 73 8 (2016): 1623-1640. http://www.scopus.com/inward/record.url?eid=2-s2.0-84962287823&partnerID=MN8TOARS. 10.1007/s00018-016-2142-0
Thesis / Dissertation	Rodrigues, Maria da Graça Soveral, 1959-; Gomes, Manuel do Carmo, 1957-; Direito, Inês Gomes. "Expression of aquaporins in pancreatic tumors: new targets for cancer therapy?". Master, 2015. http://hdl.handle.net/10451/22682.

Award

2020	Cheque MEDISIS - saúde por esse mundo fora
2019	Travel Grant para EMBO Workshop - Proteostasis: From organelles to organisms
2018	Travel Grant para EMBO Practical Course: Techniques for Mammary Gland Research