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Identification

Personal identification

Full name
Pedro Rafael Martins de Almeida Sampaio

Citation names

  • Sampaio, Pedro

Author identifiers

Ciência ID
E716-D602-CC12
ORCID iD
0000-0002-6197-1068

Websites

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Intermediate (B1) Advanced (C1) Advanced (C1) Intermediate (B1)
Spanish; Castilian Intermediate (B1) Intermediate (B1) Intermediate (B1) Intermediate (B1)
Education
Degree Classification
2016/01/02 - 2021/05/06
Concluded
Mechanisms of Disease and Regenerative Medicine (Doutoramento)
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade do Algarve, Portugal
"Uncoupling heart and liver laterality events during embryogenesis" (THESIS/DISSERTATION)
Very good with distinction and honors
2014
Concluded
Genética Molecular e Biomedicina (Mestrado)
Universidade de Lisboa Faculdade de Ciências, Portugal
"Using cilia mutants to study left-right asymmetry in zebrafish" (THESIS/DISSERTATION)
16.2 (0-20) (Thesis 18/20)
2011
Concluded
Biologia Celular e Molecular (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
"n/a" (THESIS/DISSERTATION)
13.1 (0-20)
Affiliation

Science

Category
Host institution
Employer
2021/08/01 - 2023/11/30 Researcher (Research) Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal

Others

Category
Host institution
Employer
2016 - 2021 PhD Student - funded by Fundação para Ciência e Tecnologia Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2015/07/15 - 2016/02/29 Bolsa de Investigação - Mestre Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2014/05/14 - 2015/05/15 IEFP Professional Internship - Research technician specialized in Primary Ciliary Dyskinesia diagnostic Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
2014/04/14 - 2014/06/01 Travelling Fellowship. Title: Characterization of Kupffer's vesicle cilia motility and fluid flow through time-resolved 3D high spee The Company of Biologists, United Kingdom
Universidad Nacional Autónoma de México Instituto de Biotecnología, Mexico
2011/07/01 - 2014/03/01 Mestrado Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal
Projects

Grant

Designation Funders
2019/11/01 - 2021/01/01 Excel in Rare Diseases Research: Focus on LYSOsomal Disorders and CILiopathies
PhD Student Fellow
Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal

Telethon Institute of Genetics and Medicine, Italy

Westfälische Wilhelms-Universität Münster, Germany
Horizon 2020
Ongoing
2016/03/01 - 2020/02/29 Uncoupling heart and liver laterality events during embryogenesis.
SFRH/BD/111611/2015
PhD Student Fellow
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2016/05/01 - 2019/10/31 The role of fluid dynamics in the molecular mechanisms of organ laterality.
PTDC/BEX-BID/1411/2014
PhD Student Fellow
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

iNOVA4Health, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2013/03/01 - 2017/01/30 Quantitative analysis of asymmetric gene expression in the left-right organizer in response to flow forces: what comes downstream of cilia driven flow?
FCT-ANR/BEX-BID/0153/2012
PhD Student Fellow
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade Nova de Lisboa Centro de Estudos de Doenças Crónicas, Portugal

Fundação Calouste Gulbenkian, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Conference paper
  1. Sampaio, Pedro. "Does stopping left-right nodal flow mirror impaired mechanosensation in the left-right organizer?". 2015.
    10.1186/2046-2530-4-s1-p39
  2. Sampaio, Pedro. "Pkd2 affects the architecture of zebrafish left-right organizer.". 2015.
    10.1186/2046-2530-4-s1-p84
  3. Sampaio, Pedro. "Insights into the role of Notch signalling in cilia motility regulation.". 2015.
    10.1186/2046-2530-4-s1-p81
Journal article
  1. Sampaio, Pedro; Pestana, Sara; Bota, Catarina; Guerrero, Adán; Telley, Ivo A; Smith, David; Lopes, Susana Santos. "Fluid extraction from the left-right organizer uncovers mechanical properties needed for symmetry breaking". eLife 12 (2023): http://dx.doi.org/10.7554/elife.83861.
    10.7554/elife.83861
  2. Santos, João Xavier; Sampaio, Pedro; Rasga, Célia; Martiniano, Hugo; Faria, Clarissa; Café, Cátia; Oliveira, Alexandra; et al. "Evidence for an association of prenatal exposure to particulate matter with clinical severity of Autism Spectrum Disorder". Environmental Research 228 (2023): 115795. http://dx.doi.org/10.1016/j.envres.2023.115795.
    10.1016/j.envres.2023.115795
  3. Pinto, Andreia L.; Rasteiro, Margarida; Bota, Catarina; Pestana, Sara; Sampaio, Pedro; Hogg, Claire; Burgoyne, Thomas; Lopes, Susana S.. "Zebrafish Motile Cilia as a Model for Primary Ciliary Dyskinesia". International Journal of Molecular Sciences 22 16 (2021): 8361. http://dx.doi.org/10.3390/ijms22168361.
    10.3390/ijms22168361
  4. Henriques, Ana Raquel; Constant, Carolina; Descalço, Andreia; Pinto, Andreia; Moura Nunes, J; Sampaio, Pedro; Lopes, Susana S; Pereira, Luísa; Bandeira, Teresa. "Primary ciliary dyskinesia due to CCNO mutations - A genotype-phenotype correlation contribution". Pediatric Pulmonology (2021): http://dx.doi.org/10.1002/ppul.25440.
    Published • 10.1002/ppul.25440
  5. Jacinto, Raquel; Sampaio, Pedro; Roxo-Rosa, Mónica; Pestana, Sara; Lopes, Susana S.. "Pkd2 affects cilia length and impacts LR flow dynamics and Dand5". Frontiers in Cell and Developmental Biology 9 (2021): http://dx.doi.org/10.3389/fcell.2021.624531.
    Open access • Published • 10.3389/fcell.2021.624531
  6. Sampaio, Pedro; da Silva, Mónica Ferro; Vale, Inês; Roxo-Rosa, Mónica; Pinto, Andreia; Constant, Carolina; Pereira, Luisa; Quintão, Carla M.; Lopes, Susana S.. "CiliarMove: new software for evaluating ciliary beat frequency helps find novel mutations by a Portuguese multidisciplinary team on primary ciliary dyskinesia". ERJ Open Research 7 1 (2021): 00792-2020. http://dx.doi.org/10.1183/23120541.00792-2020.
    10.1183/23120541.00792-2020
  7. Sampaio, Pedro; Burkhalter, Martin D.; Sridhar, Arthi; Sampaio, Pedro; Jacinto, Raquel; Burczyk, Martina S.; Donow, Cornelia; et al. "Imbalanced mitochondrial function provokes heterotaxy via aberrant ciliogenesis". Journal of Clinical Investigation (2019): http://dx.doi.org/10.1172/jci98890.
    10.1172/jci98890
  8. Constant, Carolina; Sousa, Rodrigo; Pinto, Andreia; Moura Nunes, J. F.; Sampaio, Pedro; Lopes, Susana Santos; Bandeira, Teresa; Pereira, Luísa. "Nova Era no Diagnóstico da Discinesia Ciliar Primária: Date of submission: 04-05-2017 | Date of acceptance: 16-11-2017 | Published: 09-07-2018". (2018): https://pjp.spp.pt//article/view/11972.
    10.25754/pjp.2018.11972
  9. Pintado, P.; Sampaio, P.; Tavares, B.; Montenegro-Johnson, T. D.; Smith, D. J.; Lopes, S. S.. "Dynamics of cilia length in left–right development". Royal Society Open Science 4 3 (2017): 161102. http://dx.doi.org/10.1098/rsos.161102.
    Open access • Published • 10.1098/rsos.161102
  10. Tavares, Barbara; Jacinto, Raquel; Sampaio, Pedro; Pestana, Sara; Pinto, Andreia; Vaz, Andreia; Roxo-Rosa, Monica; et al. "Notch/Her12 signalling modulates, motile/immotile cilia ratio downstream of Foxjla in zebrafish left-right organizer". eLife (2017): http://hdl.handle.net/10362/24535.
    https://doi.org/10.7554/eLife.25165
  11. Roxo-Rosa, Mónica; Jacinto, Raquel; Sampaio, Pedro; Lopes, Susana Santos; Sampaio, Pedro. "The zebrafish Kupffer's vesicle as a model system for the molecular mechanisms by which the lack of Polycystin-2 leads to stimulation of CFTR". Biology Open (2015): http://hdl.handle.net/10362/21522.
    https://doi.org/10.1242/bio.014076
  12. Pedro Sampaio. "Left-Right Organizer Flow Dynamics: How Much Cilia Activity Reliably Yields Laterality?". Developmental Cell (2014): http://www.sciencedirect.com/science/article/pii/S1534580714002779.
    http://dx.doi.org/10.1016/j.devcel.2014.04.030
Thesis / Dissertation
  1. Sampaio, Pedro. "Uncoupling heart and liver laterality events during embryogenesis". PhD, Universidade Nova de Lisboa Faculdade de Ciências Médicas, 2021. http://hdl.handle.net/10362/119445.
  2. Sampaio, Pedro Rafael Martins de Almeida. "Using cilia mutants to study left-right asymmetry in zebrafish". Master, 2014. http://hdl.handle.net/10362/13155.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2019/08/07 Fluid matters in a specific time window for zebrafish left-right establishment. The Biology of Cilia and Flagella Conference
FASEB Science Research (Snowmass, Colorado, United States)
2018/10/05 (Un)coupling heart and liver laterality events during embryogenesis. Cilia 2018
EMBO (Copenhagen, Denmark)
2018/02/06 Uncoupling heart and liver laterality events during embryogenesis. 3rd BEAT-PCD Conference
Faculdade de Ciências Médicas, Universidade Nova de Lisboa (Lisbon, Portugal)
2015/10/12 Is No Flow = No Pkd2 mediated sensing in the Left-Right Organizer? 9éme Meeting Cils, Flagelles et Centrosome
French National Centre for Scientific Research (Strasbourg, France)
2014/11/20 Insights into the role of Notch signalling in cilia motility regulation. Cilia Conference
Institut Louis Pasteur (Paris, France)
2014/09/19 CiliarMove: a new tool for the diagnostic of Primary Ciliary Dyskinesia by high-speed videomicroscopy. Workshop "Diagnóstico: da tecnologia ao cidadão"
Faculdade de Ciências Médicas, Universidade Nova de Lisboa (Lisbon, Portugal)

Event participation

Activity description
Type of event
Event name
Institution / Organization
2019/07/10 - 2019/07/16 LYSOCIL Exchange Program - Training in Diagnosis of Primary Ciliary Dyskinesia (PCD)
Other
LYSOCIL Exchange Program - Training in Diagnosis of Primary Ciliary Dyskinesia (PCD)
Universitätsklinikum Münster, Germany

Mentoring / Tutoring

Topic Student name
2015 - 2015 PIATI - Programa de Integração de Alunos em Trabalhos de Investigação at NOVA Medical School / CEDOC Mónica Silva
Distinctions

Award

2018 Best Oral Presentation at 3rd BEAT-PCD Conference
Vertex Pharmaceuticals Europe Ltd, United Kingdom

Other distinction

2014 Travelling Fellowship
The Company of Biologists, United Kingdom