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Invited Assistant Professor at the Faculty of Pharmacy of the University of Coimbra since 2021, with previous teaching experience at the Faculty of Health Sciences of the University of Beira Interior. Doctoral and Master's degree in Pharmaceutical Sciences from University of Beira Interior. Academic scientific research focused on the pharmaceutical sciences field, more specifically on nanotechnology, pharmaceutical technology, and analytical chemistry. Experience in teaching Pharmaceutical Sciences, Pharmaceutical Technology, Bioanalytical Sciences, Biomedical Pharmacy, and Biomedical Sciences graduate and undergraduate students. Lecture, theoretical-practical and laboratory-type classes. Past and current subjects include (alphabetical order): Applied Pharmaceutical Development; Dermopharmacy and Cosmetics; Drugs and Medicines; Galenic Pharmacy; Galenic Pharmacy and Pharmaceutical Technology; Medical Devices; Metrology and Analytical Validation; Nanotechnology; Pharmaceutical Development of Medicines; Pharmaceutical Quality Control; Pharmaceutical Technology I; Pharmaceutical Technology II; Pharmaceutical Technology III; Quality Management; Veterinary Medicines.
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Identification

Personal identification

Full name
Patrícia Sofia Cabral Pires

Citation names

  • Pires, Patrícia C.
  • Pires, P. C.
  • Patrícia C. Pires
  • P. C. Pires

Author identifiers

Ciência ID
DF1D-73CF-6BA4
ORCID iD
0000-0003-0036-4894

Knowledge fields

  • Medical and Health Sciences - Basic Medicine - Pharmacology and pharmacy
  • Engineering and Technology - Nano-technology
  • Exact Sciences - Chemical Sciences - Analytical Chemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2016/10 - 2021/03
Concluded
 Doctoral Degree in Pharmaceutical Sciences (Doutoramento)
Universidade da Beira Interior, Portugal
"The promise of prodrugs and nanosystems in nose-to-brain delivery of poorly soluble drugs: the case of phenytoin and fosphenytoin" (THESIS/DISSERTATION)
 Approved
2011/09 - 2016/06
Concluded
 Integrated Master's Degree in Pharmaceutical Sciences (Mestrado integrado)
Universidade da Beira Interior, Portugal
"Síntese de derivados da estrona funcionalizados nos anéis C e D como potenciais agentes anticancerígenos" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution 		Employer
2025 - Current Researcher (Research) RISE-Health - Health Research and Innovation, Portugal
Universidade da Beira Interior, Portugal
2022 - Current Researcher (Research) REQUIMTE LAQV Porto, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal
2014/06 - 2025/03 Researcher (Research) Universidade da Beira Centro de Investigação em Ciências da Saúde, Portugal
Universidade da Beira Centro de Investigação em Ciências da Saúde, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2021/10/01 - Current Invited Assistant Professor (University Teacher) Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/09 - 2021/03 Tutor (University Teacher) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
Projects

Grant

Designation Funders
2021 - 2022 Intranasal Delivery of Simvastatin in Stroke – IDSS
UIDP/Multi/00709/2020
Researcher
Universidade da Beira Interior Centro de Investigação em Ciências da Saúde, Portugal
2018/09 - 2020/02 ICON: Interdisciplinary Challenges On Neurodegeneration
CENTRO-01-0145-FEDER-000013
PhD Student Fellow
Universidade da Beira Centro de Investigação em Ciências da Saúde, Portugal
 Universidade da Beira Interior
Concluded
Outputs

Publications

Book chapter
  1. Pires, Patrícia C.; Amado, Maria João; Corte-Real, Margarida; Farinha, Dina; Veiga, Francisco; Faneca, Henrique; Paiva-Santos, Ana Cláudia. "Introduction and Overview of Liposomes". In Advances in Liposomal Technology in Food, Supplements and Nutraceuticals, 1-18. Royal Society of Chemistry, 2025.
    Published • 10.1039/9781837674220-00001
  2. Pires, Patrícia C.; Melo, Dora; Santos, Adriana O.. "Intranasal delivery of antiseizure drugs". In Drug Delivery Devices and Therapeutic Systems, edited by Eric Chappel, 623-646. Elsevier, 2021.
    Published • 10.1016/b978-0-12-819838-4.00022-5
Conference abstract
  1. Patrícia C. Pires. "Nanoemulgels: nanoemulsion and hydrogel hybrids as polymeric nanocomposites for improved drug delivery". Paper presented in The 3rd International Online Conference on Polymer Science, 2025.
  2. Ana Filipa São Pedro; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. "Synergistic triple drug co-loaded nanoplatforms for improved cancer treatment". Paper presented in The 1st International Electronic Conference on Medicinal Chemistry and Pharmaceutics, 2025.
  3. Maria Anastácio; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. "Innovative nanoplatforms with simultaneous triple drug co-delivery for improved synergistic therapeutic effects". Paper presented in The 1st International Electronic Conference on Medicinal Chemistry and Pharmaceutics, 2025.
  4. Mariana S. Antunes; Ana Macário-Soares ; Veiga, Francisco; Patrícia C. Pires; Ana Cláudia Paiva-Santos. "Co-encapsulation of phytocompounds in liposomes for enhanced wound healing: development and physicochemical characterization". Paper presented in The 5th International Online Conference on Nanomaterials, 2025.
  5. Nádia B. Santos; Ana Macário-Soares ; Mariana S. Antunes; Veiga, Francisco; Patrícia C. Pires; Ana Cláudia Paiva-Santos. "Development and characterization of novel plant-extract-loaded liposomes for dermopharmaceutical and cosmetic applications". Paper presented in The 5th International Online Conference on Nanomaterials, 2025.
  6. Patrícia C. Pires. "Recent advances in nanomedicine for skin cancer immunotherapy - a focus on nanosystems, drug repurposing and co-loading for synergistic effects". Paper presented in The 3rd International Electronic Conference on Biomedicines, 2025.
  7. Veiga, Francisco; Maria Beatriz Pinto; Patrícia C. Pires; Ricardo C. Calhelha; Silva, Ana Rita; Maria João Sousa; Vilas-Boas, Miguel; et al. "Nature-derived compounds and nanotechnology for cancer treatment: bee venom-loaded niosomes development and in vitro and ex vivo evaluation". Paper presented in CRSingapore 2025, 2025.
  8. Gabriel Martínez-Razo; Patrícia C. Pires; Angelica Avilez-Colin; María Lilia Domínguez-López; Veiga, Francisco; Eliezer Conde-Vazquéz; Linda A. Orozco-Maldonado; Ana Cláudia Paiva-Santos; Armando Vega-López. "Evaluation of a Norcantharidin Nanoemulsion Efficacy for Treating B16F1-Induced Melanoma in a Syngeneic Murine". Paper presented in European Academy of Dermatology and Venereology Congress, 2024.
  9. Matilde de Simão Marques; Patrícia C. Pires; Antonio José Guillot; Ana Melero; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Thermoresponsive hydrogel loaded with clobetasol PLGA nanoparticles for the treatment of inflammatory skin diseases: formulation development and characterization". Paper presented in The 5th International Electronic Conference on Applied Sciences, 2024.
  10. Margarida Corte-Real; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. "Advancing skin cancer treatment through dual drug loading into liposome-derived nanosystems". Paper presented in The 5th International Electronic Conference on Applied Sciences, 2024.
  11. Maria Araújo; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. "Novel antifungal-loaded nanoemulsions and nanoemulgels for topical melanoma treatment: preformulation studies’ optimization". Paper presented in PharmaDay - Encontro Anual de Estudantes de Doutoramento em Ciências Farmacêuticas, 2024.
  12. Matilde S. Marques; Patrícia C. Pires; Antonio J. Guillot; Ana Melero; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Development and characterization of a thermosensitive hydrogel incorporated with clobetasol-loaded PLGA nanoparticles for the treatment of inflammatory skin diseases". Paper presented in PharmaDay - Encontro Anual de Estudantes de Doutoramento em Ciências Farmacêuticas, 2024.
  13. Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Drug repurposing and nanotechnology in glioma treatment: ketoprofen nanoemulgel development and characterization for nose-to-brain delivery". Paper presented in XIX International CICS-UBI Symposium, 2024.
  14. Patrícia C. Pires; Maria Beatriz Pinto; Correia, Mafalda; Gabriela Moço; Ricardo C. Calhelha; Silva, Ana Rita; Maria João Sousa; et al. "Nanocosmetics containing nature-derived hydrophobic compounds: niosome development and physicochemical and toxicity characterization". Paper presented in XIX International CICS-UBI Symposium, 2024.
  15. Fernando Silva; Veiga, Francisco; Patrícia C. Pires; Amélia C. F. Vieira; Vera Moura; Ana Cláudia Paiva-Santos. "Development of a nanoemulsion for intravenous administration of paracetamol in combination with ketoprofen". Paper presented in XIX International CICS-UBI Symposium, 2024.
  16. Matilde R. Rodrigues; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Ketoprofen nanoemulsions: drug repurposing for potential application in melanoma treatment". Paper presented in XIX International CICS-UBI Symposium, 2024.
  17. Matilde S. Marques; Patrícia C. Pires; Antonio J. Guillot; Ana Melero; Veiga, Francisco; Ana Cláudia Paiva-Santos. "PLGA-nanoparticles for topical delivery of clobetasol: formulation development and particle size and PDI characterization". Paper presented in XIX International CICS-UBI Symposium, 2024.
  18. Maria Araújo; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Development of miconazole-loaded nanoemulsions and nanoemulgels as innovative therapeutic systems for the treatment of melanoma". Paper presented in XIX International CICS-UBI Symposium, 2024.
  19. Maria Beatriz Pinto; Patrícia C. Pires; Ricardo C. Calhelha; Silva, Ana Rita; Maria João Sousa; Vilas-Boas, Miguel; Falcão, Soraia I.; et al. "Niosomes encapsulating bee venom as a novel anticancer treatment: formulation development and evaluation of in vitro therapeutical efficacy and safety". Paper presented in XIX International CICS-UBI Symposium, 2024.
  20. Miriana Griesi; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Anthelmintic drug repurposing in cancer therapy: flubendazole-loaded nanoemulgel development for the topical treatment of melanoma". Paper presented in XIX International CICS-UBI Symposium, 2024.
  21. Isabella Felipe; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Novel nanocosmetics: curcumin nanoemulgel development and physicochemical characterization". Paper presented in XIX International CICS-UBI Symposium, 2024.
  22. Gabriel Martínez-Razo; Patrícia C. Pires; María Lilia Domínguez-López; Linda A. Orozco Maldonado; Veiga, Francisco; Armando Vega-López; Ana Cláudia Paiva-Santos. "Norcantharidin nanoemulsion development, characterization and in vitro antiproliferation effect on B16F1 melanoma cells". Paper presented in 1st International Societies for Investigative Dermatology Meeting, 2023.
  23. Matilde R. Rodrigues; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Redefining Ketoprofen: Nanoemulsion for Future Melanoma Therapeutics". Paper presented in 9th International Electronic Conference on Medicinal Chemistry, 2023.
  24. Patrícia C. Pires; Correia, Mafalda; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Anti-inflammatory drug repurposing for intranasal delivery: ketoprofen nanoemulgel development for the treatment of glioma". Paper presented in The 4th International Electronic Conference on Applied Sciences, 2023.
  25. Patrícia C. Pires; Correia, Mafalda; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Repurposing old drugs for new targets: ketoprofen intranasal nanoemulgel development for the treatment of glioma". Paper presented in X Congresso Iberoamericano de Ciências Farmacêuticas, 2023.
  26. Joana Amado; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. "Miconazole nanoemulsions for the topical treatment of melanoma: formulation development and characterization". Paper presented in X Congresso Iberoamericano de Ciências Farmacêuticas, 2023.
  27. Maria Beatriz Pinto; Correia, Mafalda; Gabriela Moço; Amélia C. F. Vieira; Veiga, Francisco; Patrícia C. Pires; Ana Cláudia Paiva-Santos. "Niosomes development and characterization for topical delivery of hydrophobic compounds". Paper presented in X Congresso Iberoamericano de Ciências Farmacêuticas, 2023.
  28. Veiga, Francisco; Patrícia C. Pires; Rui Carvalho; Matilde Rodrigues; Ana Cláudia Paiva-Santos. "Drug repurposing and nanosystems for the treatment of glioma: ketoprofen nanoemulgel development and characterization". Paper presented in Controlled Release Society 2023 Annual Meeting & Expo, 2023.
  29. Veiga, Francisco; Gabriel Martínez-Razo; Patrícia C. Pires; María Lilia Domínguez-López; Armando Vega-López; Ana Cláudia Paiva-Santos. "Norcantharidin nanoemulsion development, characterization and in vitro antiproliferation effect on B16F1 melanoma cells". Paper presented in Controlled Release Society 2023 Annual Meeting & Expo, 2023.
  30. Francisco Gama Sousa; Meirinho, Sara; Patrícia C. Pires; Alves, Gilberto; SANTOS, ADRIANA O.. "Development of Micro and Nanoemulsions for Intranasal Delivery of Simvastatin to the brain". Paper presented in 4th European Conference on Pharmaceutics, 2023.
  31. Patrícia C. Pires; Mariana Fernandes; Francisca Nina; Maria F. Gomes; Alves, Gilberto; SANTOS, ADRIANA O.. "Highly homogeneous nanoemulsion compositions by low energy emulsification: drug solubilization, modulation of drug release and promotion of bioavailability". Paper presented in 4th European Conference on Pharmaceutics, 2023.
  32. Miriana Griesi; Patrícia C. Pires; Veiga, Francisco; Giovanni Tosi; Ana Cláudia Paiva-Santos. "Development of a novel nanoemulgel for topical delivery of hydrophobic compounds". Paper presented in In4Med, 2023.
  33. Joana Amado; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Formulation development and characterization of miconazole nanoemulsions for melanoma treatment". Paper presented in In4Med, 2023.
  34. Matilde R. Rodrigues; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Drug repurposing and nanosystems for the treatment of melanoma: novel ketoprofen nanoemulsion development and characterization". Paper presented in In4Med, 2023.
  35. Maria Beatriz Pinto; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Encapsulation of hydrophilic compounds into niosomes for skin application". Paper presented in In4Med, 2023.
  36. Matilde Rodrigues; Ana Cláudia Paiva-Santos; Patrícia C. Pires; Veiga, Francisco. "Ketoprofen nanoemulsions for melanoma treatment: formulation development and characterization". Paper presented in Leiden International (Bio)Medical Student Conference (LIMSC), 2023.
  37. Ana Cláudia Paiva-Santos; Matilde Rodrigues; Patrícia C. Pires; Veiga, Francisco. "Ketoprofen nanoemulsions for melanoma treatment: formulation development and characterization". Paper presented in 13th Annual Meeting on Skin Ageing & Challenges, 2022.
  38. Matilde Rodrigues; Ana Cláudia Paiva-Santos; Patrícia C. Pires; Veiga, Francisco. "From development to characterization — Ketoprofen nanoemulsions for melanoma treatment". Paper presented in Jesien Immunologiczna Third Interdisciplinary Scientific Conference, 2022.
  39. Joana Amado; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Miconazole nanoemulsions to treat melanoma: formulation development and droplet size and solubility studies". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, 2022.
  40. Jéssica Antunes; Ana Cláudia Paiva-Santos; Veiga, Francisco; Patrícia C. Pires. "Brain targeting of antidepressant and anxiolytic drugs". Paper presented in 3rd International Electronic Conference on Applied Sciences, 2022.
  41. Maria Ferreira; Ana Cláudia Paiva-Santos; Veiga, Francisco; Patrícia C. Pires. "The importance of nanosystems in antipsychotic drugs brain targeting". Paper presented in 3rd International Electronic Conference on Applied Sciences, 2022.
  42. Margarida Alberto; Ana Cláudia Paiva-Santos; Veiga, Francisco; Patrícia C. Pires. "Intranasal nanoparticles for the treatment of depression and anxiety disorders". Paper presented in 3rd International Electronic Conference on Applied Sciences, 2022.
  43. Patrícia C. Pires; Ana Cláudia Paiva-Santos; Veiga, Francisco. "Improving drug solubility and brain bioavailability of antipsychotics through nanometric emulsions". Paper presented in 35th European College of Neuropsychopharmacology (ECNP) Congress, 2022.
  44. Patrícia C. Pires; Ana Cláudia Paiva-Santos; Veiga, Francisco. "Nanometric emulsions for the treatment of depressive and anxiety disorders". Paper presented in 35th European College of Neuropsychopharmacology (ECNP) Congress, 2022.
  45. Matilde R. Rodrigues; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Ketoprofen nanoemulsions for cancer treatment". Paper presented in 17th YES (Young European Scientist) Meeting, 2022.
  46. Patrícia C. Pires; Matilde Rodrigues; Ana Cláudia Paiva-Santos; Veiga, Francisco. "Intranasal ketoprofen nanoemulgels for brain cancer treatment: formulation development and characterization". Paper presented in XVII International CICS-UBI Symposium, 2022.
  47. Patrícia C. Pires; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Strategies to Improve Drug Strength in Nasal Preparations for Brain Delivery of Low Aqueous Solubility Drugs". Paper presented in XVII International CICS-UBI Symposium, 2022.
  48. Francisco Gama; Meirinho, Sara; Patrícia C. Pires; Alves, Gilberto; SANTOS, ADRIANA O.. "Development of a promising nanoemulsion for intranasal delivery of simvastatin in ischemic stroke". Paper presented in XVII International CICS-UBI Symposium, 2022.
  49. Francisco Gama; Meirinho, Sara; Patrícia C. Pires; SANTOS, ADRIANA O.. "Desenvolvimento de Micro e Nanoemulsões para Entrega Intranasal de Sinvastatina em AVC". Paper presented in 16º Congresso Português do AVC, 2022.
  50. Cristina Monteiro; Patrícia C. Pires; Duarte, Ana Paula; Mariana Brás; João Ribeiro; Manuel Morgado; Sandra Morgado; et al. "COVID-19 vaccine safety in a hospital: the role of pharmacovigilance". Paper presented in XVI Annual CICS-UBI Symposium 2021, 2021.
  51. Francisca S. Nina; Patrícia C. Pires; SANTOS, ADRIANA O.. "Otimização de nanoemulsões óleo-em-água com caraterísticas ideais de composição e tamanho de gotícula". Paper presented in VI Congresso Científico Anual UBIPharma, 2020.
  52. Patrícia C. Pires; Ana C. Fazendeiro; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Nose-to-brain delivery of microemulsions containing phenytoin and fosphenytoin: formulation development and pharmacokinetics". Paper presented in XV Annual CICS-UBI Symposium, 2020.
  53. Patrícia C. Pires; Liliana T. Santos; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Nose-to-brain delivery of poorly soluble drugs: the case of phenytoin and fosphenytoin - formulation development, in vitro characterization and in vivo pharmacokinetics". Paper presented in FENS 2020 Virtual Forum, 2020.
  54. Patrícia C. Pires; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Brain delivery of poorly soluble drugs: a proof-of-concept of phosphate esters as a way of increasing solubility and bioavailability". Paper presented in Controlled Release Society Virtual Annual Meeting, 2020.
  55. Patrícia C. Pires; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Intranasal administration of fosphenytoin: assay development and validation and preliminary in vivo pharmacokinetic studies". Paper presented in III International Congress in Health Sciences Research, 2019.
  56. Patrícia C. Pires; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Formulation development and in vitro characterization of nanoemulsions and nanoemulgels of phenytoin and fosphenytoin for intranasal administration". Paper presented in XIV Annual CICS-UBI Symposium, 2019.
  57. Dora Melo; Patrícia C. Pires; SANTOS, ADRIANA O.. "A review of the clinical application of intranasal benzodiazepines in the treatment of epilepsy". Paper presented in XIV Annual CICS-UBI Symposium, 2019.
  58. Patrícia C. Pires; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Simultaneous Quantification of Phenytoin and Fosphenytoin in Mouse Blood and Brain using High-Performance Liquid Chromatography: a tool for in vivo studies". Paper presented in 6th European Chemical Biology Symposium, 2019.
  59. Patrícia C. Pires; Liliana T. Santos; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Novel fosphenytoin formulations for intranasal administration - development, characterization and in vitro release studies". Paper presented in 3rd European Conference on Pharmaceutics, 2019.
  60. Liliana T. Santos; Patrícia C. Pires; SANTOS, ADRIANA O.. "Avaliação da libertação de fosfenitoína em preparações líquidas mucoadesivas ou termossensíveis". Paper presented in X Beira Interior Medical Meeting, 2019.
  61. Joana Ferreira; Patrícia C. Pires; Alves, Gilberto; SANTOS, ADRIANA O.. "The contribution of carbomer in pluronic-based thermoreversible gels of carbamazepine". Paper presented in 13th International Chemical and Biological Engineering Conference, 2018.
  62. Patrícia C. Pires; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Thermosensitive and mucoadhesive polymers in intranasal drug delivery: fosphenytoin formulation development and characterization". Paper presented in XIII Annual CICS-UBI Symposium, 2018.
  63. Patrícia C. Pires; SANTOS, ADRIANA O.. "Brain drug delivery by intranasal nanosystems: a systematic review of pre-clinical studies". Paper presented in XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  64. Catarina Canário; Matias, Mariana; Patrícia C. Pires; Brito, Vanessa; SANTOS, ADRIANA O.; Amílcar Falcão; Silvestre, Samuel; Alves, Gilberto. "Modifications of estrone in C- and D-ring: synthesis, biological evaluation and docking studies". Paper presented in XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia, 2017.
  65. Catarina Canário; Patrícia C. Pires; Brito, Vanessa; Matias, Mariana; SANTOS, ADRIANA O.; Silvestre, Samuel; Amílcar Falcão; Alves, Gilberto. "Steroidal estrone oximes: cytotoxic effects on hormone-dependent cancer cell lines". Paper presented in XI Annual CICS-UBI Symposium, 2016.
Conference paper
  1. Pires, Patrícia C.; Correia, Mafalda; Veiga, Francisco; Paiva-Santos, Ana Cláudia. "Anti-Inflammatory Drug Repurposing for Intranasal Delivery: Ketoprofen Nanoemulgel Development for the Treatment of Glioma". 2023.
    10.3390/asec2023-15345
  2. Matilde R. Rodrigues; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Redefining Ketoprofen: Nanoemulsion for Future Melanoma Therapeutics". 2023.
  3. Patrícia C. Pires; Correia, Mafalda; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Repurposing old drugs for new targets: ketoprofen intranasal nanoemulgel development for the treatment of glioma". 2023.
  4. Joana Amado; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. "Miconazole nanoemulsions for the topical treatment of melanoma: formulation development and characterization". 2023.
  5. Maria Beatriz Pinto; Correia, Mafalda; Gabriela Moço; Amélia C. F. Vieira; Veiga, Francisco; Patrícia C. Pires; Ana Cláudia Paiva-Santos. "Niosomes development and characterization for topical delivery of hydrophobic compounds". 2023.
  6. A. Vega-Lopez; Ana Cláudia Paiva-Santos; Patrícia C. Pires; M. Dominguez Lopez; L.A. Orozco-Maldonado. "Norcantharidin nanoemulsion development, characterization and in vitro antiproliferation effect on B16F1 melanoma cells". 2023.
  7. Joana Amado; Patrícia C. Pires; Francisco Veiga; Ana Cláudia Paiva-Santos. "Miconazole Nanoemulsions to Treat Melanoma: A Study of Formulation Development, Droplet Size and Solubility". 2022.
    10.3390/ecmc2022-13416
  8. P. Pires; A.C. Santos; F. Veiga. "Nanometric emulsions for the treatment of depressive and anxiety disorders". 2022.
    10.1016/j.nsa.2022.100337
  9. Jéssica Lopes Antunes; Ana Cláudia Paiva-Santos; Francisco Veiga; Patrícia C. Pires. "Brain Targeting of Antidepressant and Anxiolytic Drugs". Paper presented in Engineering Proceedings, 2022.
    10.3390/asec2022-13766
  10. Maria Ferreira; Ana Cláudia Paiva-Santos; Veiga, Francisco; Patrícia C. Pires. "The importance of nanosystems in antipsychotic drugs brain targeting". 2022.
  11. Margarida Alberto; Ana Cláudia Paiva-Santos; Veiga, Francisco; Patrícia C. Pires. "Intranasal nanoparticles for the treatment of depression and anxiety disorders". 2022.
Conference poster
  1. Veiga, Francisco; Maria Beatriz Pinto; Patrícia C. Pires; Ricardo C. Calhelha; Silva, Ana Rita; Maria João Sousa; Vilas-Boas, Miguel; et al. "Nature-derived compounds and nanotechnology for cancer treatment: bee venom-loaded niosomes development and in vitro and ex vivo evaluation". Paper presented in CRSingapore 2025, 2025.
  2. Fernando Silva; Francisco Veiga; Patrícia C. Pires; Amélia C. F. Vieira; Vera Moura; Ana Cláudia Paiva-Santos. "Development of a nanoemulsion for intravenous administration of paracetamol in combination with ketoprofen". Paper presented in XIX International CICS-UBI Symposium, 2024.
  3. Gabriel Martínez-Razo; Patrícia C. Pires; Angelica Avilez-Colin; María Lilia Domínguez-López; Veiga, Francisco; Eliezer Conde-Vazquéz; Linda A. Orozco-Maldonado; Ana Cláudia Paiva-Santos; Armando Vega-López. "Evaluation of a Norcantharidin Nanoemulsion Efficacy for Treating B16F1-Induced Melanoma in a Syngeneic Murine". Paper presented in European Academy of Dermatology and Venereology Congress, 2024.
  4. Margarida Corte-Real; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. "Advancing skin cancer treatment through dual drug loading into liposome-derived nanosystems". Paper presented in The 5th International Electronic Conference on Applied Sciences, 2024.
  5. Maria Araújo; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. "Novel antifungal-loaded nanoemulsions and nanoemulgels for topical melanoma treatment: preformulation studies’ optimization". Paper presented in PharmaDay - Encontro Anual de Estudantes de Doutoramento em Ciências Farmacêuticas, 2024.
  6. Matilde S. Marques; Patrícia C. Pires; Antonio J. Guillot; Ana Melero; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Development and characterization of a thermosensitive hydrogel incorporated with clobetasol-loaded PLGA nanoparticles for the treatment of inflammatory skin diseases". Paper presented in PharmaDay - Encontro Anual de Estudantes de Doutoramento em Ciências Farmacêuticas, 2024.
  7. Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Drug repurposing and nanotechnology in glioma treatment: ketoprofen nanoemulgel development and characterization for nose-to-brain delivery". Paper presented in XIX International CICS-UBI Symposium, 2024.
  8. Matilde R. Rodrigues; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Ketoprofen nanoemulsions: drug repurposing for potential application in melanoma treatment". Paper presented in XIX International CICS-UBI Symposium, 2024.
  9. Matilde S. Marques; Patrícia C. Pires; Antonio J. Guillot; Ana Melero; Veiga, Francisco; Ana Cláudia Paiva-Santos. "PLGA-nanoparticles for topical delivery of clobetasol: formulation development and particle size and PDI characterization". Paper presented in XIX International CICS-UBI Symposium, 2024.
  10. Maria Araújo; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Development of miconazole-loaded nanoemulsions and nanoemulgels as innovative therapeutic systems for the treatment of melanoma". Paper presented in XIX International CICS-UBI Symposium, 2024.
  11. Maria Beatriz Pinto; Patrícia C. Pires; Ricardo C. Calhelha; Silva, Ana Rita; Maria João Sousa; Vilas-Boas, Miguel; Falcão, Soraia I.; et al. "Niosomes encapsulating bee venom as a novel anticancer treatment: formulation development and evaluation of in vitro therapeutical efficacy and safety". Paper presented in XIX International CICS-UBI Symposium, 2024.
  12. Miriana Griesi; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Anthelmintic drug repurposing in cancer therapy: flubendazole-loaded nanoemulgel development for the topical treatment of melanoma". Paper presented in XIX International CICS-UBI Symposium, 2024.
  13. Isabella Felipe; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Novel nanocosmetics: curcumin nanoemulgel development and physicochemical characterization". Paper presented in XIX International CICS-UBI Symposium, 2024.
  14. Francisco Veiga; Patrícia C. Pires; Rui Carvalho; Matilde Rodrigues; Ana Cláudia Paiva-Santos. "Drug repurposing and nanosystems for the treatment of glioma: ketoprofen nanoemulgel development and characterization". Paper presented in Controlled Release Society 2023 Annual Meeting & Expo, 2023.
  15. Matilde Rodrigues; Patrícia C. Pires; Francisco Veiga; Ana Cláudia Paiva-Santos. "Drug repurposing and nanosystems for the treatment of melanoma: Novel ketoprofen nanoemulsion development and characterization". Paper presented in In4Med, 2023.
  16. Joana Amado; Patrícia C. Pires; Francisco Veiga; Ana Cláudia Paiva-Santos. "Formulation development and characterization of miconazole nanoemulsions for melanoma treatment". Paper presented in In4Med, 2023.
  17. Maria Beatriz Pinto; Patrícia C. Pires; Francisco Veiga; Ana Cláudia Paiva-Santos. "Encapsulation of hydrophilic compounds into niosomes for skin application". Paper presented in In4Med, 2023.
  18. Miriana Griesi; Patrícia C. Pires; Francisco Veiga; Giovanni Tosi; Ana Cláudia Paiva-Santos. "Development of a novel nanoemulgel for topical delivery of hydrophobic compounds". Paper presented in In4Med, 2023.
  19. Maria Beatriz Pinto; Mafalda Correia; Moço, Gabriela; Amélia Vieira; Francisco Veiga; Patrícia C. Pires; Ana Cláudia Paiva-Santos. "Niosomes development and characterization for topical delivery of hydrophobic compounds". Paper presented in X Congresso Iberoamericano das Ciências Farmacêuticas, Coimbra, Portugal, 2023.
  20. Patrícia C. Pires; Mafalda Correia; Francisco Veiga; Ana Cláudia Paiva-Santos. "Repurposing old drugs for new targets: Ketoprofen intranasal nanoemulgel development for the treatment of glioma". Paper presented in X Congresso Iberoamericano das Ciências Farmacêuticas, Coimbra, Portugal, 2023.
  21. Joana Amado; Francisco Veiga; Ana Cláudia Paiva-Santos; Patrícia C. Pires. "Miconazole nanoemulsions for the topical treatment of melanoma: Formulation development and characterization". Paper presented in X Congresso Iberoamericano das Ciências Farmacêuticas, Coimbra, Portugal, 2023.
  22. Gabriel Martínez-Razo; Patrícia C. Pires; María Lilia Domínguez-López; Linda A. Orozco Maldonado; Veiga, Francisco; Armando Vega-López; Ana Cláudia Paiva-Santos. "Norcantharidin nanoemulsion development, characterization and in vitro antiproliferation effect on B16F1 melanoma cells". Paper presented in 1st International Societies for Investigative Dermatology Meeting, 2023.
  23. Matilde R. Rodrigues; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. "Redefining Ketoprofen: Nanoemulsion for Future Melanoma Therapeutics". Paper presented in 9th International Electronic Conference on Medicinal Chemistry, 2023.
  24. Veiga, Francisco; Gabriel Martínez-Razo; Patrícia C. Pires; María Lilia Domínguez-López; Armando Vega-López; Ana Cláudia Paiva-Santos. "Norcantharidin nanoemulsion development, characterization and in vitro antiproliferation effect on B16F1 melanoma cells". Paper presented in Controlled Release Society 2023 Annual Meeting & Expo, 2023.
  25. Francisco Gama Sousa; Meirinho, Sara; Patrícia C. Pires; Alves, Gilberto; SANTOS, ADRIANA O.. "Development of Micro and Nanoemulsions for Intranasal Delivery of Simvastatin to the brain". Paper presented in 4th European Conference on Pharmaceutics, 2023.
  26. Patrícia C. Pires; Mariana Fernandes; Francisca Nina; Maria F. Gomes; Alves, Gilberto; SANTOS, ADRIANA O.. "Highly homogeneous nanoemulsion compositions by low energy emulsification: drug solubilization, modulation of drug release and promotion of bioavailability". Paper presented in 4th European Conference on Pharmaceutics, 2023.
  27. Joana Amado; Patrícia C. Pires; Francisco Veiga; Ana Cláudia Paiva-Santos. "Miconazole nanoemulsions to treat melanoma: formulation development and droplet size and solubility studies". Paper presented in 8th International Electronic Conference on Medicinal Chemistry, 2022.
  28. Ana Cláudia Paiva-Santos; Matilde Rodrigues; Patrícia C. Pires; Francisco Veiga. "Ketoprofen Nanoemulsions for Melanoma Treatment: Formulation, Development and Characterization". Paper presented in 13th Annual Meeting on Skin Ageing & Challenges, 2022.
  29. Patrícia C. Pires; Ana Cláudia Paiva-Santos; Francisco Veiga. "Improving drug solubility and brain bioavailability of antipsychotics through nanometric emulsions". Paper presented in 35th European College of Neuropsychopharmacology (ECNP) Congress, 2022.
  30. Matilde Rodrigues; Patrícia C. Pires; Francisco Veiga; Ana Cláudia Paiva-Santos. "Ketoprofen nanoemulsions for cancer treatment". Paper presented in 17th YES - Young European Scientist Meeting, 2022.
  31. Patrícia C. Pires; Matilde Rodrigues; Ana Cláudia Paiva-Santos; Francisco Veiga. "Intranasal ketoprofen nanoemulgels for brain cancer treatment: formulation development and characterization". Paper presented in XVII International CICS-UBI Symposium, 2022.
  32. Gama, Francisco; Meirinho, Sara; Patrícia C. Pires; Adriana O. Santos. "Desenvolvimento de Micro e Nanoemulsões para Entrega Intranasal de Sinvastatina em AVC". Paper presented in 16º Congresso Português do AVC, 2022.
  33. Patrícia C. Pires; Ana Cláudia Paiva-Santos; Veiga, Francisco. "Nanometric emulsions for the treatment of depressive and anxiety disorders". Paper presented in 35th European College of Neuropsychopharmacology (ECNP) Congress, 2022.
  34. Patrícia C. Pires; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. "Strategies to Improve Drug Strength in Nasal Preparations for Brain Delivery of Low Aqueous Solubility Drugs". Paper presented in XVII International CICS-UBI Symposium, 2022.
  35. Cristina Monteiro; Patrícia C. Pires; Duarte, Ana Paula; Mariana Brás; João Ribeiro; Manuel Morgado; Sandra Morgado; et al. "COVID-19 vaccine safety in a hospital: the role of pharmacovigilance". Paper presented in XVI Annual CICS-UBI Symposium, 2021.
  36. Francisca S. Nina; Patrícia C. Pires; SANTOS, ADRIANA O.. "Otimização de nanoemulsões óleo-em-água com caraterísticas ideais de composição e tamanho de gotícula". Paper presented in VI Congresso Científico Anual UBIPharma, 2020.
  37. Patrícia C. Pires; Márcio Rodrigues; Gilberto Alves; SANTOS, ADRIANA O.. "Brain delivery of poorly soluble drugs: a proof-of-concept of phosphate esters as a way of increasing solubility and bioavailability". Paper presented in Controlled Release Society Virtual Annual Meeting, 2020.
  38. Patrícia C. Pires; Liliana T. Santos; Márcio Rodrigues; Gilberto Alves; SANTOS, ADRIANA O.. "Nose-to-brain delivery of poorly soluble drugs: the case of phenytoin and fosphenytoin - formulation development, in vitro characterization and in vivo pharmacokinetics". Paper presented in FENS 2020 Virtual Forum, 2020.
  39. Patrícia C. Pires; Ana C. Fazendeiro; Márcio Rodrigues; Gilberto Alves; SANTOS, ADRIANA O.. "Nose-to-brain delivery of microemulsions containing phenytoin and fosphenytoin: formulation development and pharmacokinetics". Paper presented in XV Annual CICS-UBI Symposium, 2020.
  40. Dora Melo; Patrícia C. Pires; Adriana O. Santos. "A review of the clinical application of intranasal benzodiazepines in the treatment of epilepsy". Paper presented in XIV Annual CICS-UBI Symposium, 2019.
  41. Patrícia C. Pires; Márcio Rodrigues; Gilberto Alves; Adriana O. Santos. "Simultaneous quantification of phenytoin and fosphenytoin in mouse blood and brain using high-performance liquid chromatography: a tool for in vivo studies". Paper presented in 6th European Chemical Biology Symposium, 2019.
  42. Patrícia C. Pires; Liliana T. Santos; Márcio Rodrigues; Gilberto Alves; Adriana O. Santos. "Novel fosphenytoin formulations for intranasal administration - development, characterization and in vitro release studies". Paper presented in 3rd European Conference on Pharmaceutics, 2019.
  43. Liliana T. Santos; Patrícia C. Pires; SANTOS, ADRIANA O.. "Avaliação da libertação de fosfenitoína em preparações líquidas mucoadesivas ou termossensíveis". Paper presented in X Beira Interior Medical Meeting, 2019.
  44. Patrícia C. Pires; Adriana O. Santos. "Brain drug delivery by intranasal nanosystems: a systematic review of pre-clinical studies". Paper presented in XII Spanish-Portuguese Conference on Controlled Drug Delivery, 2018.
  45. Joana Ferreira; Patrícia C. Pires; Gilberto Alves; SANTOS, ADRIANA O.. "The contribution of carbomer in pluronic-based thermoreversible gels of carbamazepine". Paper presented in 13th International Chemical and Biological Engineering Conference, 2018.
  46. Catarina Canário; Patrícia C. Pires; Mariana Matias; Vanessa de Brito; Adriana O. Santos; Amílcar Falcão; Samuel Silvestre; Gilberto Alves. "Steroidal estrone oximes: cytotoxic effects on hormone-dependent cancer cell lines". Paper presented in XI Annual CICS-UBI Symposium, 2016.
Journal article
  1. Santos, Soraia; Lopes, Joana; Lopes, Daniela; Moradialvand, Madineh; Hameed, Huma; Pires, Patrícia C.; Damiri, Fouad; et al. "Biomembrane-Derived vesicles for targeted cancer Therapies: Novel treatment avenues from Cells, Bacteria, and extracellular sources". European Journal of Pharmaceutics and Biopharmaceutics 218 (2026): 114935. https://doi.org/10.1016/j.ejpb.2025.114935.
    10.1016/j.ejpb.2025.114935
  2. Pires, Patrícia C.; Magalhães, Mariana; Cabral, Célia; Veiga, Francisco; Mazzola, Priscila Gava; Paiva-Santos, Ana Cláudia. "Development and characterization of novel intranasal in situ thermoreversible ketoprofen-loaded nanoemulgels for the treatment of glioblastoma". Journal of Drug Delivery Science and Technology 114 (2025): 107580. https://doi.org/10.1016/j.jddst.2025.107580.
    10.1016/j.jddst.2025.107580
  3. Ferreira, Patrícia; Ataide, Janaína Artem; Babaie, Soraya; Vieira, Amélia C. F.; Costa, Gustavo; Pires, Patrícia C.; Mazzola, Priscila Gava; et al. "Ectoine as a multifunctional molecule: biotechnological production and pharmaceutical applications". Drug Delivery and Translational Research (2025): https://doi.org/10.1007/s13346-025-02024-2.
    10.1007/s13346-025-02024-2
  4. Rodrigues, Sara; Veiga, Francisco; Paiva-Santos, Ana Cláudia; Pires, Patrícia C.. "Dual drug co-encapsulation into liposomes and liposome-derived nanosystems for improved synergistic treatment of skin diseases". Drug Delivery and Translational Research (2025): https://doi.org/10.1007/s13346-025-02016-2.
    10.1007/s13346-025-02016-2
  5. Rodrigues, Matilde R.; Pires, Patrícia C.; Melero, Ana; Guillot, Antonio José; Borrego-Sánchez, Ana; Sesarman, Alina; Banciu, Manuela; Veiga, Francisco; Paiva-Santos, Ana Cláudia. "Anti-inflammatory drug repurposing in skin diseases: ketoprofen-loaded nanoemulsion development and characterization for topical administration". European Journal of Pharmacology 1004 (2025): 177992. https://doi.org/10.1016/j.ejphar.2025.177992.
    10.1016/j.ejphar.2025.177992
  6. Pinto, Maria Beatriz; Pires, Patrícia C.; Correia, Mafalda; Moço, Gabriela; Sousa-Oliveira, Inês; Sousa, Maria João; Calhelha, Ricardo C.; et al. "Propolis-Loaded Niosomes for Dermopharmaceutic and Cosmetic Applications: Development, Stability, Safety, and In Vitro Bioactivity Studies". ACS Pharmacology & Translational Science 8 7 (2025): 2220-2246. https://doi.org/10.1021/acsptsci.5c00253.
    10.1021/acsptsci.5c00253
  7. Pereira, Ana Rita; Pires, Patrícia C.; Hameed, Huma; Lopes, Daniela; Lopes, Joana; Sousa-Oliveira, Inês; Babaie, Soraya; et al. "Injectable nanocomposite hydrogels for targeted intervention in cancer, wound healing, and bone and myocardial tissue engineering". Drug Delivery and Translational Research 15 9 (2025): 2994-3077. https://doi.org/10.1007/s13346-025-01864-2.
    10.1007/s13346-025-01864-2
  8. Couceiro, Beatriz; Hameed, Huma; Vieira, Amélia C.F.; Singh, Sachin Kumar; Dua, Kamal; Veiga, Francisco; Pires, Patrícia C.; Ferreira, Laura; Paiva-Santos, Ana Cláudia. "Promoting health and sustainability: exploring safer alternatives in cosmetics and regulatory perspectives". Sustainable Chemistry and Pharmacy 43 (2025): 101901. https://doi.org/10.1016/j.scp.2024.101901.
    10.1016/j.scp.2024.101901
  9. Martínez-Razo, Gabriel; Pires, Patrícia C.; Avilez-Colin, Angélica; Domínguez-López, María Lilia; Veiga, Francisco; Conde-Vázquez, Eliezer; Paiva-Santos, Ana Cláudia; Vega-López, Armando. "Evaluation of a Norcantharidin Nanoemulsion Efficacy for Treating B16F1-Induced Melanoma in a Syngeneic Murine Model". International Journal of Molecular Sciences 26 3 (2025): 1215. https://doi.org/10.3390/ijms26031215.
    10.3390/ijms26031215
  10. Martins, Maria; Veiga, Francisco; Paiva-Santos, Ana Cláudia; Pires, Patrícia C.. "Drug Repurposing and Nanotechnology for Topical Skin Cancer Treatment: Redirecting toward Targeted and Synergistic Antitumor Effects". ACS Pharmacology & Translational Science 8 2 (2025): 308-338. https://doi.org/10.1021/acsptsci.4c00679.
    10.1021/acsptsci.4c00679
  11. Gama, Francisco; Meirinho, Sara; Pires, Patrícia C.; Tinoco, Johann; Martins Gaspar, Maria Carolina; Baltazar, Graça; Alves, Gilberto; Santos, Adriana O.. "Simvastatin is delivered to the brain by high-strength intranasal cationic SMEDDS and nanoemulsions". Drug Delivery and Translational Research 15 8 (2025): 2749-2764. https://doi.org/10.1007/s13346-024-01769-6.
    10.1007/s13346-024-01769-6
  12. Faria, Marta; Ferreira-Faria, Inês; Sousa-Oliveira, Inês; Pires, Patrícia C.; Hameed, Huma; Silva, Fernando; Moço, Gabriela; et al. "Engineered biomimetic cell membrane-coated polymeric nanostructures for cancer therapy". Materials Today Chemistry 43 (2025): 102506. https://doi.org/10.1016/j.mtchem.2024.102506.
    10.1016/j.mtchem.2024.102506
  13. Pires, Patrícia C.; Renca, Andreia; Amaro, Inês; Parreiras, Lara; Anselmo, Márcia; Ferreira, Maria; Veiga, Francisco; Paiva-Santos, Ana Cláudia. "From stimuli-responsive polymers to nanosystems and electrocircuits: An update on the current state of polymeric hydrogel microneedles for wound healing". Journal of Drug Delivery Science and Technology 102 (2024): 106395. https://doi.org/10.1016/j.jddst.2024.106395.
    10.1016/j.jddst.2024.106395
  14. Ferreira, Laura; Torres, Beatriz; Hameed, Huma; Vieira, Amélia C.F.; Singh, Sachin Kumar; Dua, Kamal; Veiga, Francisco; et al. "Updated insights of active cosmetic ingredients against blue light: In vivo and in vitro evidence". Journal of Drug Delivery Science and Technology 101 (2024): 106306. https://doi.org/10.1016/j.jddst.2024.106306.
    10.1016/j.jddst.2024.106306
  15. Macário-Soares, Ana; Sousa-Oliveira, Inês; Correia, Mafalda; Pires, Patrícia C.; Sharma, Ankur; Kumar Jha, Niraj; Zare, Ehsan Nazarzadeh; et al. "Cell membrane and extracellular vesicle membrane-coated nanoparticles: An envisaged approach for the management of skin conditions". VIEW 5 6 (2024): https://doi.org/10.1002/viw.20240043.
    10.1002/viw.20240043
  16. Gonçalves, Maria Beatriz S.; Marques, Mário Pedro; Correia, Fernando; Pires, Patrícia C.; Correia, Mafalda; Makvandi, Pooyan; Varela, Carla; et al. "Wine industry by-products as a source of active ingredients for topical applications". Phytochemistry Reviews 24 5 (2024): 4065-4099. https://doi.org/10.1007/s11101-024-10030-4.
    10.1007/s11101-024-10030-4
  17. Pires, Patrícia C.; Motallebi, Mahzad; Marques, Mário Pedro; Correia, Mafalda; Sharma, Ankur; Damiri, Fouad; Hameed, Huma; et al. "Mentha aquatica (Water Mint) as a Source of Active Pharmaceutical and Cosmetic Ingredients: A Critical Review". Phytotherapy Research 38 12 (2024): 5806-5839. https://doi.org/10.1002/ptr.8337.
    10.1002/ptr.8337
  18. Corte-Real, Margarida; Veiga, Francisco; Paiva-Santos, Ana Cláudia; Pires, Patrícia C.. "Improving Skin Cancer Treatment by Dual Drug Co-Encapsulation into Liposomal Systems—An Integrated Approach towards Anticancer Synergism and Targeted Delivery". Pharmaceutics 16 9 (2024): 1200. https://doi.org/10.3390/pharmaceutics16091200.
    10.3390/pharmaceutics16091200
  19. Duarte, Joana; Mascarenhas-Melo, Filipa; Pires, Patrícia C.; Veiga, Francisco; Paiva-Santos, Ana Cláudia. "Multifunctional hydrogels-based therapies for chronic diabetic wound healing". European Polymer Journal 211 (2024): 113026. https://doi.org/10.1016/j.eurpolymj.2024.113026.
    10.1016/j.eurpolymj.2024.113026
  20. Pinto, Maria Beatriz; Pires, Patrícia C.; Calhelha, Ricardo C.; Silva, Ana Rita; Sousa, Maria João; Vilas-Boas, Miguel; Falcão, Soraia I.; et al. "Bee Venom-Loaded Niosomes as Innovative Platforms for Cancer Treatment: Development and Therapeutical Efficacy and Safety Evaluation". Pharmaceuticals 17 5 (2024): 572. https://doi.org/10.3390/ph17050572.
    10.3390/ph17050572
  21. Pires, Patrícia C.; Damiri, Fouad; Zare, Ehsan Nazarzadeh; Hasan, Anwarul; Neisiany, Rasoul Esmaeely; Veiga, Francisco; Makvandi, Pooyan; Paiva-Santos, Ana Cláudia. "A review on natural biopolymers in external drug delivery systems for wound healing and atopic dermatitis". International Journal of Biological Macromolecules 263 (2024): 130296. https://doi.org/10.1016/j.ijbiomac.2024.130296.
    10.1016/j.ijbiomac.2024.130296
  22. Sghier, Kamil; Mur, Maja; Veiga, Francisco; Paiva-Santos, Ana Cláudia; Pires, Patrícia C.. "Novel Therapeutic Hybrid Systems Using Hydrogels and Nanotechnology: A Focus on Nanoemulgels for the Treatment of Skin Diseases". Gels 10 1 (2024): 45. https://doi.org/10.3390/gels10010045.
    10.3390/gels10010045
  23. Duarte, Joana; Sharma, Ankur; Sharifi, Esmaeel; Damiri, Fouad; Berrada, Mohammed; Khan, Moonis Ali; Singh, Sachin Kumar; et al. "Topical delivery of nanoemulsions for skin cancer treatment". Applied Materials Today 35 (2023): 102001. https://doi.org/10.1016/j.apmt.2023.102001.
    10.1016/j.apmt.2023.102001
  24. Eliana Veiga; Laura Ferreira; Mafalda Rodrigues Luis Correia; Patrícia C. Pires; Huma Hameed; Andre RTS Araujo; Letícia Caramori Cefali; et al. "Anti-aging peptides for advanced skincare: Focus on nanodelivery systems". Journal of Drug Delivery Science and Technology 89 (2023): 105087-105087. http://dx.doi.org/10.1016/j.jddst.2023.105087.
    10.1016/j.jddst.2023.105087
  25. Pires, Patrícia C.; Paiva-Santos, Ana Cláudia; Veiga, Francisco. "Liposome-Derived Nanosystems for the Treatment of Behavioral and Neurodegenerative Diseases: The Promise of Niosomes, Transfersomes, and Ethosomes for Increased Brain Drug Bioavailability". Pharmaceuticals 16 10 (2023): 1424. https://doi.org/10.3390/ph16101424.
    10.3390/ph16101424
  26. Ana Cláudia Paiva-Santos; Tatiana Gonçalves; Diana Peixoto; Patrícia C. Pires; K. Velsankar; Niraj Kumar Jha; Vivek Chavda; et al. "Rosacea Topical Treatment and Care: From Traditional to New Drug Delivery Systems". Molecular Pharmaceutics 20 8 (2023): 3804-3828. http://dx.doi.org/10.1021/acs.molpharmaceut.3c00324.
    10.1021/acs.molpharmaceut.3c00324
  27. Pires, Patrícia C.; Fernandes, Mariana; Nina, Francisca; Gama, Francisco; Gomes, Maria F.; Rodrigues, Lina E.; Meirinho, Sara; et al. "Innovative Aqueous Nanoemulsion Prepared by Phase Inversion Emulsification with Exceptional Homogeneity". Pharmaceutics 15 7 (2023): 1878. https://doi.org/10.3390/pharmaceutics15071878.
    10.3390/pharmaceutics15071878
  28. Beatriz P. Ferreira; Gustavo Costa; Filipa Mascarenhas-Melo; Patrícia C. Pires; Fariba Heidarizadeh; Prabhanjan S. Giram; Priscila Gava Mazzola; et al. "Skin applications of cannabidiol: sources, effects, delivery systems, marketed formulations and safety". Phytochemistry Reviews 22 3 (2023): 781-828. http://dx.doi.org/10.1007/s11101-023-09860-5.
    10.1007/s11101-023-09860-5
  29. Badalkhani, Omolbanin; Pires, Patrícia C.; Mohammadi, Maryam; Babaie, Soraya; Paiva-Santos, Ana Cláudia; Hamishehkar, Hamed. "Nanogel Containing Gamma-Oryzanol-Loaded Nanostructured Lipid Carriers and TiO2/MBBT: A Synergistic Nanotechnological Approach of Potent Natural Antioxidants and Nanosized UV Filters for Skin Protection". Pharmaceuticals 16 5 (2023): 670. https://doi.org/10.3390/ph16050670.
    10.3390/ph16050670
  30. Cruz, Ana M.; Gonçalves, Margarida C.; Marques, Matilde S.; Veiga, Francisco; Paiva-Santos, Ana Cláudia; Pires, Patrícia C.. "In Vitro Models for Anti-Aging Efficacy Assessment: A Critical Update in Dermocosmetic Research". Cosmetics 10 2 (2023): 66. https://doi.org/10.3390/cosmetics10020066.
    10.3390/cosmetics10020066
  31. Patrícia C. Pires; Filipa Mascarenhas-Melo; Kelly Pedrosa; Daniela Lopes; Joana Lopes; Ana Macário-Soares; Diana Peixoto; et al. "Polymer-based biomaterials for pharmaceutical and biomedical applications: A focus on topical drug administration". European Polymer Journal 187 (2023): 111868-111868. http://dx.doi.org/10.1016/j.eurpolymj.2023.111868.
    10.1016/j.eurpolymj.2023.111868
  32. Martínez-Razo, Gabriel; Pires, Patrícia C.; Domínguez-López, María Lilia; Veiga, Francisco; Vega-López, Armando; Paiva-Santos, Ana Cláudia. "Norcantharidin Nanoemulsion Development, Characterization, and In Vitro Antiproliferation Effect on B16F1 Melanoma Cells". Pharmaceuticals 16 4 (2023): 501. https://doi.org/10.3390/ph16040501.
    10.3390/ph16040501
  33. Ferreira, Laura; Pires, Patrícia C.; Fonseca, Mariana; Costa, Gustavo; Giram, Prabhanjan Shridhar; Mazzola, Priscila Gava; Bell, Victoria; et al. "Nanomaterials in Cosmetics: An Outlook for European Regulatory Requirements and a Step Forward in Sustainability". Cosmetics 10 2 (2023): 53. https://doi.org/10.3390/cosmetics10020053.
    10.3390/cosmetics10020053
  34. Antunes, Jéssica L.; Amado, Joana; Veiga, Francisco; Paiva-Santos, Ana Cláudia; Pires, Patrícia C.. "Nanosystems, Drug Molecule Functionalization and Intranasal Delivery: An Update on the Most Promising Strategies for Increasing the Therapeutic Efficacy of Antidepressant and Anxiolytic Drugs". Pharmaceutics 15 3 (2023): 998. https://doi.org/10.3390/pharmaceutics15030998.
    10.3390/pharmaceutics15030998
  35. Ferreira, Maria Daniela; Duarte, Joana; Veiga, Francisco; Paiva-Santos, Ana Cláudia; Pires, Patrícia C.. "Nanosystems for Brain Targeting of Antipsychotic Drugs: An Update on the Most Promising Nanocarriers for Increased Bioavailability and Therapeutic Efficacy". Pharmaceutics 15 2 (2023): 678. https://doi.org/10.3390/pharmaceutics15020678.
    10.3390/pharmaceutics15020678
  36. Patrícia C. Pires; Ana Cláudia Paiva-Santos; Francisco Veiga. "Nano and Microemulsions for the Treatment of Depressive and Anxiety Disorders: An Efficient Approach to Improve Solubility, Brain Bioavailability and Therapeutic Efficacy". Pharmaceutics 14 12 (2022): 2825-2825. http://dx.doi.org/10.3390/pharmaceutics14122825.
    10.3390/pharmaceutics14122825
  37. Margarida Alberto; Ana Cláudia Paiva-Santos; Francisco Veiga; Patrícia C. Pires. "Lipid and Polymeric Nanoparticles: Successful Strategies for Nose-to-Brain Drug Delivery in the Treatment of Depression and Anxiety Disorders". Pharmaceutics 14 12 (2022): 2742-2742. http://dx.doi.org/10.3390/pharmaceutics14122742.
    10.3390/pharmaceutics14122742
  38. Joana Lopes; Daniela Lopes; Ana Macário-Soares; Inês Ferreira-Faria; Diana Peixoto; Mahzad Motallebi; Imran Mohammad; et al. "Cell Membrane-Coated Biomaterials for Bone Cancer-Targeted Diagnosis and Therapy: A Critical Update on Osteosarcoma Applications". Materials Chemistry Horizons (2022): https://doi.org/10.22128/mch.2022.615.1032.
    10.22128/mch.2022.615.1032
  39. Patrícia C. Pires; Ana Cláudia Paiva-Santos; Francisco Veiga. "Antipsychotics-Loaded Nanometric Emulsions for Brain Delivery". Pharmaceutics 14 10 (2022): 2174-2174. http://dx.doi.org/10.3390/pharmaceutics14102174.
    10.3390/pharmaceutics14102174
  40. Pires, Patrícia C.; Rodrigues, Márcio; Alves, Gilberto; Santos, Adriana O.. "Strategies to Improve Drug Strength in Nasal Preparations for Brain Delivery of Low Aqueous Solubility Drugs". Pharmaceutics 14 3 (2022): 588. https://doi.org/10.3390/pharmaceutics14030588.
    10.3390/pharmaceutics14030588
  41. Canário, Catarina; Matias, Mariana; Brito, Vanessa; Pires, Patrícia; Santos, Adriana O.; Falcão, Amílcar; Silvestre, Samuel; Alves, Gilberto. "C-Ring Oxidized Estrone Acetate Derivatives: Assessment of Antiproliferative Activities and Docking Studies". Applied Sciences 12 7 (2022): 3579. https://doi.org/10.3390/app12073579.
    10.3390/app12073579
  42. Pires, Patrícia C.; Fazendeiro, Ana C.; Rodrigues, Márcio; Alves, Gilberto; Santos, Adriana O.. "Nose-to-brain delivery of phenytoin and its hydrophilic prodrug fosphenytoin combined in a microemulsion - formulation development and in vivo pharmacokinetics.". European Journal of Pharmaceutical Sciences 164 (2021): 105918. https://doi.org/10.1016/j.ejps.2021.105918.
    10.1016/j.ejps.2021.105918
  43. Pires, Patrícia C.; Santos, Liliana T.; Rodrigues, Márcio; Alves, Gilberto; Santos, Adriana O.. "Intranasal fosphenytoin: The promise of phosphate esters in nose-to-brain delivery of poorly soluble drugs". International Journal of Pharmaceutics 592 (2021): 120040. https://doi.org/10.1016/j.ijpharm.2020.120040.
    10.1016/j.ijpharm.2020.120040
  44. Pires, Patrícia C.; Peixoto, Diana; Teixeira, Isaura; Rodrigues, Márcio; Alves, Gilberto; Santos, Adriana O.. "Nanoemulsions and thermosensitive nanoemulgels of phenytoin and fosphenytoin for intranasal administration: Formulation development and in vitro characterization". European Journal of Pharmaceutical Sciences 141 (2020): 105099. https://doi.org/10.1016/j.ejps.2019.105099.
    10.1016/j.ejps.2019.105099
  45. Pires, Patrícia C.; Santos, Adriana O.. "Nanosystems in nose-to-brain drug delivery: A review of non-clinical brain targeting studies". Journal of Controlled Release 270 (2018): 89-100. https://doi.org/10.1016/j.jconrel.2017.11.047.
    10.1016/j.jconrel.2017.11.047
Online resource
  1. Patrícia C. Pires. Nanoemulgels: nanoemulsion and hydrogel hybrids as polymeric nanocomposites for improved drug delivery. 2025. https://sciforum.net/paper/view/27072.
  2. Ana Filipa São Pedro; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. Synergistic triple drug co-loaded nanoplatforms for improved cancer treatment. 2025. https://sciforum.net/paper/view/25604.
  3. Maria Anastácio; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. Innovative nanoplatforms with simultaneous triple drug co-delivery for improved synergistic therapeutic effects. 2025. https://sciforum.net/paper/view/25628.
  4. Mariana S. Antunes; Ana Macário-Soares ; Veiga, Francisco; Patrícia C. Pires; Ana Cláudia Paiva-Santos. Co-encapsulation of phytocompounds in liposomes for enhanced wound healing: development and physicochemical characterization. 2025. https://sciforum.net/paper/view/24059.
  5. Nádia B. Santos; Ana Macário-Soares ; Mariana S. Antunes; Veiga, Francisco; Patrícia C. Pires; Ana Cláudia Paiva-Santos. Development and characterization of novel plant-extract-loaded liposomes for dermopharmaceutical and cosmetic applications. 2025. https://sciforum.net/paper/view/24049.
  6. Patrícia C. Pires. Recent advances in nanomedicine for skin cancer immunotherapy - a focus on nanosystems, drug repurposing and co-loading for synergistic effects. 2025. https://sciforum.net/paper/view/22458.
  7. Matilde de Simão Marques; Patrícia C. Pires; Antonio José Guillot; Ana Melero; Veiga, Francisco; Ana Cláudia Paiva-Santos. Thermoresponsive hydrogel loaded with clobetasol PLGA nanoparticles for the treatment of inflammatory skin diseases: formulation development and characterization. 2024. https://sciforum.net/paper/view/21046.
  8. Margarida Corte-Real; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. Advancing skin cancer treatment through dual drug loading into liposome-derived nanosystems. 2024. https://sciforum.net/paper/view/21112.
  9. Kamil Sghier; Maja Mur; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. Therapeutic Hybrid Systems Using Hydrogels and Nanotechnology. 2024. https://encyclopedia.pub/entry/53599.
  10. Laura Ferreira; Patrícia C. Pires; Fonseca, Mariana; Gustavo Costa; Giram, Prabhanjan S.; Mazzola, Priscila Gava; Bell, Victoria; et al. Nanomaterials in Cosmetics. 2023. https://encyclopedia.pub/entry/42715.
  11. Matilde R. Rodrigues; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. Redefining Ketoprofen: Nanoemulsion for Future Melanoma Therapeutics. 2023. https://sciforum.net/paper/view/15724.
  12. Patrícia C. Pires; Correia, Mafalda; Veiga, Francisco; Ana Cláudia Paiva-Santos. Anti-inflammatory drug repurposing for intranasal delivery: ketoprofen nanoemulgel development for the treatment of glioma. 2023. https://sciforum.net/paper/view/15345.
  13. Patrícia C. Pires; Ana Cláudia Paiva-Santos; Veiga, Francisco. Liposome-Derived Nanosystems for Increased Brain Drug Bioavailability. 2023. https://encyclopedia.pub/entry/50195.
  14. Ana M. Cruz; Margarida C. Gonçalves; Matilde S. Marques; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. In Vitro Models for Anti-Aging Efficacy Assessment. 2023. https://encyclopedia.pub/entry/43562.
  15. Jéssica L. Antunes; Joana Amado; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. Enhancing Brain Drug Bioavailability in Depression and Anxiety. 2023. https://encyclopedia.pub/entry/42637.
  16. Maria Ferreira; Duarte, Joana; Veiga, Francisco; Ana Cláudia Paiva-Santos; Patrícia C. Pires. Second Generation Antipsychotics. 2023. https://encyclopedia.pub/entry/41699.
  17. Margarida Alberto; Ana Cláudia Paiva-Santos; Francisco Veiga; Patrícia C. Pires. Intranasal Nanoparticles for the Treatment of Depression and Anxiety Disorders. 2022. https://sciforum.net/paper/view/13853.
    10.3390/asec2022-13853
  18. Patrícia C. Pires; Ana Cláudia Paiva-Santos; Francisco Veiga. Nanosystems for Brain Drug Delivery. 2022. https://encyclopedia.pub/entry/33306.
  19. Margarida Alberto; Ana Cláudia Paiva-Santos; Francisco Veiga; Patrícia C. Pires. Lipid and Polymeric Nanoparticles for Brain Drug Delivery. 2022. https://encyclopedia.pub/entry/38768.
  20. Patrícia C. Pires; Ana Cláudia Paiva-Santos; Francisco Veiga. Nano and Microemulsions for Depression and Anxiety Treatment. 2022. https://encyclopedia.pub/entry/39040.
  21. Joana Amado; Patrícia C. Pires; Veiga, Francisco; Ana Cláudia Paiva-Santos. Miconazole nanoemulsions to treat melanoma: formulation development and droplet size and solubility studies. 2022. https://sciforum.net/paper/view/13416.
  22. Jéssica Antunes; Ana Cláudia Paiva-Santos; Veiga, Francisco; Patrícia C. Pires. Brain targeting of antidepressant and anxiolytic drugs. 2022. https://sciforum.net/paper/view/13766.
  23. Maria Ferreira; Ana Cláudia Paiva-Santos; Veiga, Francisco; Patrícia C. Pires. The importance of nanosystems in antipsychotic drugs brain targeting. 2022. https://sciforum.net/paper/view/13765.
  24. Patrícia C. Pires; Rodrigues, Márcio; Alves, Gilberto; SANTOS, ADRIANA O.. Strategies to Improve Drug Strength in Nasal Preparations. 2022. https://encyclopedia.pub/entry/33359.

Intellectual property

Patent
  1. SANTOS, ADRIANA O.; Mariana Carvalho Fernandes; Patrícia C. Pires; Alves, Gilberto; Ana Carolina Maricoto Fazendeiro; Francisca Matos Silva Pereira Nina; Maria De Fátima da Silva Ferreira Gomes; Rodrigues, Lina. 2021. "Emulsão homogénea para entrega de agentes ativos, seus métodos e usos/ Self-emulsifying composition, production methods and uses thereof".
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2025 Nanoemulgels: nanoemulsion and hydrogel hybrids as polymeric nanocomposites for improved drug delivery The 3rd International Online Conference on Polymer Science
2025 Pharmaceutical particle processes for therapeutic applications: advancements in nanoemulsions and nanoemulgels for improved cancer treatment The 4th International Electronic Conference on Processes
2025 Recent advances in nanomedicine for skin cancer immunotherapy - a focus on nanosystems, drug repurposing and co-loading for synergistic effects The 3rd International Electronic Conference on Biomedicines
2025 Nanossistemas como terapias inovadoras para patologias do cérebro e da pele Unidade curricular de Introdução ao Projeto I, do Mestrado em Tecnologias do Medicamento
Universidade de Coimbra
2025 Synergistic triple drug co-loaded nanoplatforms for improved cancer treatment The 1st International Electronic Conference on Medicinal Chemistry and Pharmaceutics
2025 Innovative nanoplatforms with simultaneous triple drug co-delivery for improved synergistic therapeutic effects The 1st International Electronic Conference on Medicinal Chemistry and Pharmaceutics
2025 Co-encapsulation of phytocompounds in liposomes for enhanced wound healing: development and physicochemical characterization The 5th International Online Conference on Nanomaterials
2025 Development and characterization of novel plant extract-loaded liposomes for dermopharmaceutical and cosmetic applications The 5th International Online Conference on Nanomaterials
2024 Pós e granulados Unidade curricular de Tecnologia Farmacêutica, do Curso de Especialização Avançada em Radiofarmácia
Universidade de Coimbra
2024 Thermoresponsive hydrogel loaded with clobetasol PLGA nanoparticles for the treatment of inflammatory skin diseases: formulation development and characterization The 5th International Electronic Conference on Applied Sciences
2024 Nanocosmetics containing nature-derived hydrophobic compounds: niosome development and physicochemical and toxicity characterization XIX International CICS-UBI Symposium
2023 Nanosystems for topical application: a focus on drug repurposing and natural compounds for therapeutic and cosmetic purposes Lunch Seminar CICS-UBI
2023 Ketoprofen nanoemulsions for melanoma treatment: formulation development and characterization Leiden International (Bio)Medical Student Conference (LIMSC)
2022 Investigação em Ciências Farmacêuticas: moléculas e formulações Unidade curricular de Investigação em Ciências Farmacêuticas, do Mestrado Integrado em Ciências Farmacêuticas
Universidade da Beira Interior
2022 From development to characterization — Ketoprofen nanoemulsions for melanoma treatment Jesien Immunologiczna Third Interdisciplinary Scientific Conference
2022 Brain targeting of antidepressant and anxiolytic drugs 3rd International Electronic Conference on Applied Sciences
2022 The importance of nanosystems in antipsychotic drugs brain targeting 3rd International Electronic Conference on Applied Sciences
2022 Intranasal nanoparticles for the treatment of depression and anxiety disorders 3rd International Electronic Conference on Applied Sciences
2022 Development of a promising nanoemulsion for intranasal delivery of simvastatin in ischemic stroke XVII International CICS-UBI Symposium
2019/11 Intranasal administration of fosphenytoin: assay development and validation and preliminary in vivo pharmacokinetic studies III International Congress in Health Sciences Research
(Covilhã, Portugal)
2019/07 Formulation development and in vitro characterization of nanoemulsions and nanoemulgels of phenytoin and fosphenytoin for intranasal administration XIV Annual CICS-UBI Symposium
(Covilhã, Portugal)
2018/07 Thermosensitive and mucoadhesive polymers in intranasal drug delivery: fosphenytoin formulation development and characterization XIII Annual CICS-UBI Symposium
(Covilhã, Portugal)
2017 Modifications of estrone in C- and D-ring: synthesis, biological evaluation and docking studies XLVII Reunião Anual da Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2025 - Current Triple drug co-delivery within nanometric multifunctional platforms for synergistically improved cancer treatment
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2025 - Current Innovative nanoplatforms with simultaneous triple drug delivery for improved synergistic therapeutic effects
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2025 - Current Novel antihypertensive drug-loaded nanoemulsions and nanoemulgels for topical melanoma treatment: pre-formulation studies’ optimization
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2024 - Current Thermoresponsive hydrogel loaded with clobetasol PLGA nanoparticles for the treatment of inflammatory skin diseases: formulation development and characterization
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2024 - Current Drug Co-Encapsulation into Liposome-Derived Nanosystems for the Treatment of Skin Diseases
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2024 - Current Improving skin cancer treatment by dual drug co-encapsulation into liposomes and derived nanosystems
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - Current Drug Repurposing for Skin Cancer Treatment: A Nanotechnological Approach
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - Current Drug Repurposing and Nanosystems for Cutaneous Melanoma Treatment: development and characterization of a miconazole oi-in-water nanoemulsion
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - Current Propolis-Encapsulated Niosomes for Topical Delivery
Co-supervisor
 Tecnologias do Medicamento (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - Current Novel nanoemulgel for topical delivery of flubendazole in melanoma: preformulation studies and characterization
Co-supervisor
 Química e Tecnologia Farmacêutica (Master)
Università degli Studi di Modena e Reggio Emilia, Italy
2023 - Current Direcionamento cerebral de fármacos antidepressivos e ansiolíticos
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 - Current A importância dos nanossistemas no direcionamento cerebral de fármacos antipsicóticos
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 - Current Nanotechnology in Photoprotection
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 - Current Nanopartículas intranasais para o tratamento da depressão e ansiedade
Supervisor
 Ciências Farmacêuticas (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 - Current Desenvolvimento e avaliação da eficácia de emulsões nanométricas de sinvastatina para o tratamento do AVC
Co-supervisor
 Ciências Biomédicas (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2021 - Current Eficácia da administração intranasal de micro e nanoemulsões na biodisponibilidade e direcionamento cerebral de fármacos de baixa massa molecular
Co-supervisor
 Ciências Farmacêuticas (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2021 - Current Otimização de nanoemulsões óleo-em-água com caraterísticas ideais de composição e tamanho de gotícula
Co-supervisor
 Ciências Farmacêuticas (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2021 - Current Desenvolvimento de microemulsões de fenitoína e fosfenitoína
Co-supervisor
 Ciências Farmacêuticas (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2020 - Current Revisão de modelos de epitélio nasal humano nos estudos pré-clínicos de segurança
Co-supervisor of Iryna Denysyuk
 Ciências Farmacêuticas (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2019 - Current Avaliação da libertação de fosfenitoína em preparações líquidas mucoadesivas ou termossensíveis
Co-supervisor of Liliana Santos
 Ciências Farmacêuticas (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2019 - Current Revisão da aplicação clínica de benzodiazepinas pela via intranasal no tratamento da epilepsia
Co-supervisor of Dora Melo
 Ciências Farmacêuticas (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2019 - 2021 Formulação de emulsões nanométricas de fenitoina e fosfenitoina
Co-supervisor of Ana C. Fazendeiro
 Pharmaceutical Sciences (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023 - Current Moderadora no evento +Talks, Associação Cura+, Painel II "Emergência do futuro: Saúde vs Ambiente", tema "O desperdício da cosmética: produtos vegetais e os seus desafios" (2023)
2023 - Current Júri da competição do IV Compounding Event “Formulação Magistral: Medicamentos Manipulados em Geriatria” (2023)

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2025 Centella asiatica and Its Phytocompounds-Based Delivery Systems for Skin Applications
(Thesis) Arguer
 Maria Sacramento (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2025 Dual phytochemical loaded liposomes for enhanced topical therapeutic efficiency in wound healing
(Thesis) Arguer
 Mariana Antunes (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2025 Triple drug co-delivery within nanometric multifunctional platforms for synergistically improved cancer treatment
Supervisor
 Ana Pedro (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2025 Innovative nanoplatforms with simultaneous triple drug delivery for improved synergistic therapeutic effects
Supervisor
 Maria Anastácio (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2025 Novel antihypertensive drug-loaded nanoemulsions and nanoemulgels for topical melanoma treatment: pre-formulation studies’ optimization
Supervisor
 Maria Araújo (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2024 Repurposed drugs for topical treatment of cutaneous melanoma
(Thesis) Arguer
 Matilde Rodrigues (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2024 Drug Co-Encapsulation into Liposome-Derived Nanosystems for the Treatment of Skin Diseases
Supervisor
 Sara Rodrigues (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2024 Thermoresponsive hydrogel loaded with clobetasol PLGA nanoparticles for the treatment of inflammatory skin diseases: formulation development and characterization
Supervisor
 Matilde Marques (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2024 Improving skin cancer treatment by dual drug co-encapsulation into liposomes and derived nanosystems
Supervisor
 Margarida Corte-Real (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 Injectable nanocomposite hydrogels for targeted and local interventions in cancer, wound healing, and tissue engineering
(Thesis) Arguer
 Ana Pereira (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 Nanocarriers-based topical treatments for skin cancer: focus on cutaneous melanoma
(Thesis) Arguer
 Beatriz Gomes (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 Anti-aging peptides for skin application: focus on nanodelivery systems
(Thesis) Arguer
 Eliana Veiga (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 Drug Repurposing and Nanosystems for Cutaneous Melanoma Treatment: development and characterization of a miconazole oil-in-water nanoemulsion
Supervisor
 Joana Amado (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 Drug Repurposing for Skin Cancer Treatment: A Nanotechnological Approach
Supervisor
 Maria Martins (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 Direcionamento cerebral de fármacos antidepressivos e ansiolíticos
Supervisor
 Jéssica Antunes (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 NSAIDS-loaded nanocarriers for next generation cancer treatment
(Thesis) Arguer
 Carolina Mesquita (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 Desenvolvimento e otimização de nanoemulsões catiónicas
(Thesis) Arguer
 Rita Bullha (Master)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2022 A importância dos nanossistemas no direcionamento cerebral de fármacos antipsicóticos
Supervisor
 Daniela Ferreira (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 Nanotechnology in Photoprotection
Supervisor
 Sara Vilela (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 Nanopartículas intranasais para o tratamento da depressão e ansiedade
Supervisor
 Margarida Alberto (Master)
Universidade de Coimbra Faculdade de Farmácia, Portugal

Conference scientific committee

Conference name Conference host
2025 - Current The 4th International Electronic Conference on Processes
2025 - Current The 3rd International Electronic Conference on Biomedicines

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022 - 2026 Tecnologia Farmacêutica II Tecnologia Farmacêutica II (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2024 - 2025 Desenvolvimento Farmacêutico Aplicado Desenvolvimento Farmacêutico Aplicado (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2024 - 2025 Nanotecnologias Nanotecnologias (Mestrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2022 - 2025 Fármacos e Medicamento Fármacos e Medicamento (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 - 2025 Controlo de Qualidade de Medicamentos Controlo de Qualidade de Medicamentos (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 - 2025 Metrologia e Validação Analítica Metrologia e Validação Analítica (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - 2024 Desenvolvimento Farmacêutico do Medicamento Desenvolvimento Farmacêutico do Medicamento (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - 2024 Dispositivos Médicos Dispositivos Médicos (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - 2024 Organização e Gestão da Qualidade Organização e Gestão da Qualidade (Licenciatura) Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - 2024 Preparações de Uso Veterinário Preparações de Uso Veterinário (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 - 2024 Tecnologia Farmacêutica III Tecnologia Farmacêutica III (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 - 2023 Dermofarmácia e Cosmética Dermofarmácia e Cosmética (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 - 2023 Farmácia Galénica Farmácia Galénica (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2021 - 2023 Tecnologia Farmacêutica I Tecnologia Farmacêutica I (Mestrado integrado) Universidade de Coimbra Faculdade de Farmácia, Portugal
2017 - 2021 Farmácia Galénica e Tecnologia Farmacêutica Farmácia Galénica e Tecnologia Farmacêutica (Mestrado integrado) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2019 - 2020 Seminário Seminário (Licenciatura) Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal

Mentoring / Tutoring

Topic Student name
2023 - Current Kamil Sghier
2023 - Current Maja Mur
2023 - Current Joana Amado

Other jury / evaluation

Activity description Institution / Organization
2024 - Current Vogal do procedimento concursal para atribuição de 2 bolsas de investigação para mestre do projeto “Panthermicell - Micelas Biomiméticas à Base de Vitamina e Revestidas por Membrana Celular para Nanoteranóstica Multimodal do Cancro do Pâncreas”, IT137-24-91 Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - Current Vogal do procedimento concursal para atribuição de 1 bolsa de investigação para doutorado do projeto “NanoBioGel - Hidrogel de nanotubos de argila haloisite com revestimento biomimético à base de produtos naturais para a cicatrização cutânea de feridas”, IT137-23-240 Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - Current Vogal do procedimento concursal para atribuição de 1 bolsa de investigação para licenciado do projeto “NanoBioGel - Hidrogel de nanotubos de argila haloisite com revestimento biomimético à base de produtos naturais para a cicatrização cutânea de feridas”, IT137-23-241 Universidade de Coimbra Faculdade de Farmácia, Portugal
2023 - Current Vogal do procedimento concursal para atribuição de 2 bolsas de investigação para mestre do projeto “Panthermicell - Micelas Biomiméticas à Base de Vitamina e Revestidas por Membrana Celular para Nanoteranóstica Multimodal do Cancro do Pâncreas”, IT137-23-049 Universidade de Coimbra Faculdade de Farmácia, Portugal
Distinctions

Award

2024 2024 MDPI Top 1000 Reviewers
MDPI AG, Switzerland
2024 Stanford/Elsevier Top 2% Scientists 2024
2024 Highly Cited Papers 2024: “Polymer-based biomaterials for pharmaceutical and biomedical applications: a focus on topical drug administration”, European Polymer Journal
2024 Highly Cited Papers 2024: “A review on natural biopolymers in external drug delivery systems for wound healing and atopic dermatitis”, International Journal of Biological Macromolecules
2023 Antibiotics 2023 Outstanding Reviewer Award
MDPI AG, Switzerland
2023 Medicines 2023 Outstanding Reviewer Award
MDPI AG, Switzerland
2023 4º lugar na competição de comunicações orais e posters do congresso "In4Med"
2023 6º lugar na competição de comunicações orais e posters do congresso "In4Med"
2022 1º prémio na II Sessão de trabalhos de estudantes no congresso "Jesien Immunologiczna Third Interdisciplinary Scientific Conference"
2020 1º prémio na competição científica no "VI Congresso Científico Anual UBIPharma"
2019 Melhor comunicação oral no "III International Congress in Health Sciences Research", Covilhã, Portugal
Universidade da Beira Interior Instituto Coordenador da Investigação, Portugal
2019 1º prémio na categoria não-clínica da competição científica no congresso "X Beira Interior Medical Meeting"

Other distinction

2023 Capa de edição: “Skin Applications of Cannabidiol: Sources, Effects, Delivery Systems, Marketed Formulations and Safety”, Phytochemistry Reviews
2022 Editors Choice Articles 2022: “Strategies to Improve Drug Strength in Nasal Preparations for Brain Delivery of Low Aqueous Solubility Drugs”, Pharmaceutics