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H. Fernandes obtained his Applied Biology degree from the University of Minho (Portugal) after performing an internship at the Faculty of Medicine, University Complutense Madrid (Spain) under the supervision of Prof. J Regueiro. After graduating, H. Fernandes joined the group of Prof. C van Blitterswijk and Prof. J de Boer at the University of Twente (The Netherlands) where he completed his PhD in 2009. During this period, H. Fernandes made important contributions to the field of Bone Tissue Engineering by unravelling the biomaterial-driven molecular mechanisms governing the differentiation of human stem cells into osteoblasts. During his post-doctoral studies, H. Fernandes established the use of high-throughput screening (HTS) technologies to identify and study the role of small molecules on endothelial differentiation and function. His main findings were published in the top journals in the field (e.g., PNAS and Biomaterials). In 2011, H. Fernandes was invited to lead a new research group at the University of Twente focusing on the development of translational technologies for tendon and ligament regeneration. An important goal of the group was the development of technologies that could reach the Clinic within a short period of time and thus, a novel peptide-based platform capable of capturing endogenous growth factors, in a spatially-controlled manner, was developed. During this period, H. Fernandes supervised, full-time, 2 PhD students and 1 visiting PhD student from Rutgers University (USA) as well as 6 MSc and 6 BSc students. The results obtained led to the publication of 7 peer-review articles and the submission of a patent (P113734NL00). In 2014, H. Fernandes secured a grant from the Foundation for Science and Technology (FCT) and joined the Centre for Neuroscience and Cell Biology (Portugal) focusing on the implementation of HTS platforms to identify miRNAs capable of modulating stem cell fate and survival. During this period, H. Fernandes supervised 1 postdoctoral fellow, 2 MSc and 1 BSc Student and the results obtained were published in PNAS and a patent (PCT/IB2013/061110). In 2017, H. Fernandes joined the ERA Chair team of Prof. Lino Ferreira at the Faculty of Medicine (University of Coimbra, Portugal) where he focused on: (i) discovering of miRNAs capable of inhibiting or delaying cellular senescence and (ii) developing exosome-based drug delivery platforms. In 2020, H. Fernandes received the prestigious Stimuli to Scientific Employment Award from FCT to develop his research in the field of Molecular Bioengineering with special emphasis on the use of bioengineered exosomes for Regenerative Medicine. Currently, H. Fernandes supervises 4 PhD students working on Molecular Bioengineering of exosomes and on the role of non-coding RNAs in Regenerative Medicine. H. Fernandes has published 43 papers in peer-reviewed journals with >1700 citations (h-index of 17 - Publons), including papers in high impact factor journals in the field (PNAS, Biomaterials, Acta Biomaterialia). During the last 7 years, H. Fernandes secured more than 1 million Euros from Industry (600k from Smith&Nephew - 2012-16), Academia (60k from Co-tutella agreement University of Coimbra - University Maastricht; 2016-20) and from National and Internationally funding agencies (130k 2013-15 and 201k 2018-21 from FCT; 323k Netherlands Organization for Health Research and Development - 2017-22). H. Fernandes acts as referee for several journals (Biomaterials, Theranostics, Advanced Therapy, Tissue Engineering, Frontiers in Bioengineering, Acta Biomaterials amongst others) and as Evaluator for several funding agencies (Sklodowska-Curie Individual Fellowships from EU - 2017-22, French National Research Agency, Dunhill Medical Trust, Swiss National Science Foundation, Action Medical Research and Polish Science Foundation. Since 2019, H Fernandes is Board Member (Secretary) of the Portuguese Society for Stem Cells and Cell Therapy.
Identification

Personal identification

Full name
Hugo Agostinho Machado Fernandes
Date of birth
1977/10/16
Gender
Male

Citation names

  • Fernandes, Hugo
  • Hugo Machado Fernandes
  • Fernandes, H.A.M.

Author identifiers

Ciência ID
CE15-5259-CC1D
ORCID iD
0000-0002-4574-7648
Google Scholar ID
https://scholar.google.pt/citations?user=fzRUwicAAAAJ&hl=en
Researcher Id
H-6192-2014

Email addresses

  • hugo.fernandes@uc.pt (Professional)
  • h.fernandes@me.com (Personal)

Telephones

Telephone
  • 231249170 (Professional)

Addresses

  • UC-Biotech, Biocant Parque; Nucleo 4, Lote 8, 3060-197, Cantanhede, Cantanhede, Portugal (Professional)

Websites

  • https://advancedtherapies.cibb.uc.pt (Professional)
  • https://www.cnc.uc.pt/en/research-group/act-advanced-cell-technology (Professional)

Knowledge fields

  • Engineering and Technology - Other Engineering and Technologies
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Proficiency (C2) Proficiency (C2) Advanced (C1) Proficiency (C2) Advanced (C1)
Spanish; Castilian Upper intermediate (B2) Advanced (C1) Elementary (A2) Advanced (C1) Elementary (A2)
Education
Degree Classification
2013
Concluded
Designing a lesson and a course (Outros)
Universiteit Twente, Netherlands
2013
Concluded
University Teaching Qualification (Pós-Graduação)
Universiteit Twente, Netherlands
2013
Concluded
Guidelines and legislation for clinical trials in human subjects (Outros)
Universiteit Twente, Netherlands
2012
Concluded
Time Management course (Outros)
Universiteit Twente, Netherlands
2012
Concluded
Testing and assessment (Outros)
Universiteit Twente, Netherlands
2012
Concluded
Supervising final projects (Outros)
Universiteit Twente, Netherlands
2012
Concluded
Policy of Education and course coordination (Outros)
Universiteit Twente, Netherlands
2011
Concluded
Certification program for Ingenuity Pathway Analysis (Outros)
QIAGEN Bioinformatics, United States
2010 - 2010
Concluded
Dutch course – Follow-up III (Outros)
Universiteit Twente, Netherlands
2010
Concluded
Analysis of microarray gene expression data (Outros)
Universiteit Leiden, Netherlands
2009
Concluded
Biomedical Engineering (Doutoramento)
Universiteit Twente, Netherlands
"Instructive Elements for Bone Tissue Engineering" (THESIS/DISSERTATION)
N/A
2009
Concluded
Intensive week Dutch Course (Outros)
Universiteit Twente, Netherlands
2009
Concluded
Dutch course – Follow-up I (Outros)
Universiteit Twente, Netherlands
2009
Concluded
Dutch course – Follow-up II (Outros)
Universiteit Twente, Netherlands
2007
Concluded
Presentation Skills course (Outros)
Universiteit Twente, Netherlands
2007
Concluded
Technical writing and Editing training program (Outros)
Universiteit Twente, Netherlands
2005
Concluded
Laboratory Animal Science (Outros)
Universiteit Utrecht, Netherlands
2004
Concluded
Safety and Occupational Health (Pós-Graduação)
Worfocus, Portugal
2002
Concluded
Applied Biology (Licenciatura)
Universidade do Minho, Portugal
"Immunopathologies of T lymphocytes" (THESIS/DISSERTATION)
14
1998
Attended
Systems Engineering and Computer Science (Licenciatura)
Universidade do Minho Escola de Engenharia, Portugal
"N/A" (THESIS/DISSERTATION)
N/A
1995/07/11
Concluded
Natural Sciences (Ensino secundário)
Colégio Dom Diogo de Sousa, Portugal
"N/A" (THESIS/DISSERTATION)
N/A
Affiliation

Science

Category
Host institution
Employer
2018/11/17 - Current Invited Principal Investigator (Research) University Coimbra - Faculty Medicine, Portugal
2017/11/17 - 2018/11/16 Invited Auxiliary Researcher (Research) University Coimbra - Faculty Medicine, Portugal
2014/01/01 - 2017/11/16 Auxiliary Researcher (Research) CNC.IBILI, Portugal
2011/09/01 - 2013/12/31 Auxiliary Researcher (Research) Universiteit Twente, Netherlands
2004/01/01 - 2004/09/01 Researcher (Research) Universidade do Minho, Portugal

Others

Category
Host institution
Employer
2020/11/16 - Current Auxiliary Investigator - Scientific Employment Stimulus Award (FCT) University Coimbra - Faculty Medicine, Portugal
2009/02/01 - 2011/08/01 Postdoctoral Fellow Universiteit Twente, Netherlands
2004/11/01 - 2009/01/31 Ph.D Student Universiteit Twente, Netherlands
2002/03/01 - 2002/08/01 Erasmus Exchange Student Universidad Complutense de Madrid Facultad de Medicina, Spain
Projects

Grant

Designation Funders
2015 - Current Role of microRNAs in chondrogenesis of human mesenchymal stromal cells
NA
Integration into Research Grant Fellow
Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Netherlands
2018 - 2021/08 Exo-Heart: cardiac protection and regeneration mediated by systemic administration of targeted exosomes
029919
Fundação para a Ciência e a Tecnologia
2017 - 2021/06/01 Towards personalized beta-cell mass imaging in type 2 Diabetes
95105008
Integration into Research Grant Fellow
ZonMw, Netherlands
ZonMw
2013 - 2015/06 Combinatorial approaches to promote cell survival - PROSURVIVAL
125994
Provided by PTCRIS: 125994
Fundação para a Ciência e a Tecnologia, I.P.

Contract

Designation Funders
2012 - 2016/02/01 Validation of bone marrow aspirate concentrator for reconstructive medicine
NA
Principal investigator
Smith & Nephew, United States
2012 - 2016/02/01 Advanced Tendon and Ligament Healing
NA
Principal investigator
Smith & Nephew, United States
Outputs

Publications

Book chapter
  1. Thakkar, Shraddha; Fernandes, Hugo; Moroni, Lorenzo. "Decellularized Extracellular Matrix Scaffolds for Cartilage Regeneration". In Cartilage Tissue Engineering, 133-151. Springer New York, 2015.
    10.1007/978-1-4939-2938-2_9
  2. Fernandes, Hugo; Roderick Beijersbergen; Lino Ferreira; Koen Dechering; Prabhas Moghe; Katharina Maniura-Weber. "Bioassay Development". In Materiomics: high-Throughput Screening of Biomaterial Properties. Cambridge University Press, 2013.
  3. Fernandes, Hugo; Frits Hulshof; Er Liu; Andrea Negro; Samy Gobaa; Matthias Lutolf; Prabhas Moghe. "High-content Imaging". In Materiomics: high-Throughput Screening of Biomaterial Properties. Cambridge University Press, 2013.
Conference poster
  1. Fernandes, Hugo; Alessandra Zonnari; Ricardo Abreu; Sezin Aday; Marta Barão; Ines Albino; Miguel Lino; et al. "Extracellular vehicles enriched with an endothelial cell pro- survival microrna impacts skin tissue regeneration". Paper presented in 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, 2022.
  2. Fernandes, Hugo; Ricardo Abreu; Miguel Lino; Cristiana Ramos; Clarissa Becher; Carlos Jesus; Paula Martins; et al. "Biomolecular engineering of extracellular vesicles with micrornas". Paper presented in 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies, 2022.
Journal article
  1. Fernandes, Hugo; Zonnari, Alessandra; Abreu, Ricardo; Aday, Sezin; Barão, Marta; Albino, Inês; Lino, Miguel; et al. Corresponding author: Fernandes, Hugo. "Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration". Molecular Therapy - Nucleic Acids 28 (2022): 307-327. http://dx.doi.org/10.1016/j.omtn.2022.03.018.
    10.1016/j.omtn.2022.03.018
  2. Ottaviani, L.; Juni, R.P.; de Abreu, R.C.; Sansonetti, M.; Sampaio-Pinto, V.; Halkein, J.; Hegenbarth, J.C.; et al. "Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells". Molecular Therapy (2022): http://dx.doi.org/10.1016/j.ymthe.2022.03.002.
    10.1016/j.ymthe.2022.03.002
  3. Inês Tomé; Vitor Francisco; Hugo Fernandes; Lino Ferreira. "High-throughput screening of nanoparticles in drug delivery". APL Bioengineering (2021): https://doi.org/10.1063/5.0057204.
    10.1063/5.0057204
  4. Abreu, Ricardo C.; Ramos, Cristiana V.; Becher, Clarissa; Lino, Miguel; Jesus, Carlos; Costa Martins, Paula A.; Martins, Patrícia A. T.; et al. Corresponding author: Fernandes, Hugo. "Exogenous loading of miRNAs into small extracellular vesicles". Journal of Extracellular Vesicles 10 10 (2021): http://dx.doi.org/10.1002/jev2.12111.
    Open access • 10.1002/jev2.12111
  5. Francisco, Vitor; Rebelo, Catarina; Rodrigues, Artur Filipe; Blersch, Josephine; Fernandes, Hugo; Ferreira, Lino. Corresponding author: Ferreira, Lino. "A high-throughput screening platform to identify nanocarriers for efficient delivery of RNA-based therapies". Methods (2020): http://dx.doi.org/10.1016/j.ymeth.2020.12.002.
    10.1016/j.ymeth.2020.12.002
  6. de Abreu, Ricardo Cerqueira; Fernandes, Hugo; da Costa Martins, Paula A.; Sahoo, Susmita; Emanueli, Costanza; Ferreira, Lino. "Native and bioengineered extracellular vesicles for cardiovascular therapeutics". Nature Reviews Cardiology 17 11 (2020): 685-697. http://dx.doi.org/10.1038/s41569-020-0389-5.
    10.1038/s41569-020-0389-5
  7. Pádua, Diana; Barros, Rita; Amaral, Ana Luísa; Mesquita, Patrícia; Freire, Ana Filipa; Sousa, Mafalda; Maia, André Filipe; et al. "A SOX2 Reporter System Identifies Gastric Cancer Stem-Like Cells Sensitive to Monensin". Cancers 12 2 (2020): 495. http://dx.doi.org/10.3390/cancers12020495.
    10.3390/cancers12020495
  8. Rosa, Susana; Pitrez, Patrícia; Fernandes, Hugo; Ferreira, Lino. Corresponding author: Fernandes, Hugo. "A High-Throughput Screening Method to Identify Compounds Displaying Human Vascular Embryonic Toxicity". Current Protocols in Stem Cell Biology 50 1 (2019): http://dx.doi.org/10.1002/cpsc.93.
    10.1002/cpsc.93
  9. Othman, Ziryan; Fernandes, Hugo; Groot, Arjan J.; Luider, Theo M.; Alcinesio, Alessandro; Pereira, Daniel de Melo; Guttenplan, Alexander P.M.; Yuan, Huipin; Habibovic, Pamela. "The role of ENPP1/PC-1 in osteoinduction by calcium phosphate ceramics". Biomaterials 210 (2019): 12-24. http://dx.doi.org/10.1016/j.biomaterials.2019.04.021.
    10.1016/j.biomaterials.2019.04.021
  10. Honglin Chen; Danielle F. Baptista; Giuseppe Criscenti; João Crispim; Hugo Fernandes; Clemens van Blitterswijk; Roman Truckenmüller; Lorenzo Moroni. "From fiber curls to mesh waves: a platform for the fabrication of hierarchically structured nanofibers mimicking natural tissue formation". Nanoscale 11 30 (2019): 14312-14321. https://doi.org/10.1039/C8NR10108F.
    10.1039/C8NR10108F
  11. Criscenti G; De Maria C; Longoni A; van Blitterswijk CA; Fernandes HAM; Vozzi G; Moroni L. "Soft-molecular imprinted electrospun scaffolds to mimic specific biological tissues.". Biofabrication (2018): http://europepmc.org/abstract/med/30024388.
    10.1088/1758-5090/aad48a
  12. Crispim JF; Fu SC; Lee YW; Fernandes HAM; Jonkheijm P; Yung PSH; Saris DBF. "Bioactive Tape With BMP-2 Binding Peptides Captures Endogenous Growth Factors and Accelerates Healing After Anterior Cruciate Ligament Reconstruction.". The American journal of sports medicine (2018): http://europepmc.org/abstract/med/30074814.
    10.1177/0363546518787507
  13. Ghebes, Corina Adriana; Groen, Nathalie; Cheuk, Yau Chuk; Fu, Sai Chuen; Fernandes, Hugo Machado; Saris, Daniel B.F.. Corresponding author: Fernandes, Hugo Machado. "Muscle-Secreted Factors Improve Anterior Cruciate Ligament Graft Healing: An In Vitro and In Vivo Analysis". Tissue Engineering Part A 24 3-4 (2018): 322-334. http://dx.doi.org/10.1089/ten.tea.2016.0546.
    10.1089/ten.tea.2016.0546
  14. Ekwueme, Emmanuel C.; Mohiuddin, Mahir; Yarborough, Jazmin A.; Brolinson, P. Gunnar; Docheva, Denitsa; Fernandes, Hugo A. M.; Freeman, Joseph W.. "Prolotherapy Induces an Inflammatory Response in Human Tenocytes In Vitro". Clinical Orthopaedics and Related Research® 475 8 (2017): 2117-2127. http://dx.doi.org/10.1007/s11999-017-5370-1.
    10.1007/s11999-017-5370-1
  15. Vazão H; Rosa S; Barata T; Costa R; Pitrez PR; Honório I; de Vries MR; et al. "High-throughput identification of small molecules that affect human embryonic vascular development.". (2017): http://europepmc.org/abstract/med/28348206.
    10.1073/pnas.1617451114
  16. Crispim, J.; Fernandes, H.A.M.; Fu, S.C.; Lee, Y.W.; Jonkheijm, P.; Saris, D.B.F.. "TGF-ß1 activation in human hamstring cells through growth factor binding peptides on polycaprolactone surfaces". Acta Biomaterialia 53 (2017): 165-178. http://dx.doi.org/10.1016/j.actbio.2017.01.066.
    10.1016/j.actbio.2017.01.066
  17. Romão, Joana; Barata, David; Ribeiro, Nelson; Habibovic, Pamela; Fernandes, Hugo; Mul, Guido. Corresponding author: Fernandes, Hugo. "High throughput screening of photocatalytic conversion of pharmaceutical contaminants in water". Environmental Pollution 220 (2017): 1199-1207. http://dx.doi.org/10.1016/j.envpol.2016.11.015.
    10.1016/j.envpol.2016.11.015
  18. Ghebes CA; Braham MV; Zeegers AV; Renard AJ; Fernandes H; Saris DB. Corresponding author: Fernandes H. "Means of enhancing bone fracture healing: optimal cell source, isolation methods and acoustic stimulation.". (2016): http://europepmc.org/abstract/med/27955656.
  19. Ghebes, Corina-Adriana; van Lente, Jéré; Post, Janine Nicole; Saris, Daniel B. F.; Fernandes, Hugo. Corresponding author: Fernandes, Hugo. "High-Throughput Screening Assay Identifies Small Molecules Capable of Modulating the BMP-2 and TGF-ß1 Signaling Pathway". SLAS DISCOVERY: Advancing Life Sciences R&D 22 1 (2016): 40-50. http://dx.doi.org/10.1177/1087057116669346.
    10.1177/1087057116669346
  20. Ekwueme, Emmanuel C.; Shah, Jay V.; Mohiuddin, Mahir; Ghebes, Corina A.; Crispim, João F.; Saris, Daniël B.F.; Fernandes, Hugo A.M.; Freeman, Joseph W.. "Cross-Talk Between Human Tenocytes and Bone Marrow Stromal Cells Potentiates Extracellular Matrix Remodeling In Vitro". Journal of Cellular Biochemistry 117 3 (2015): 684-693. http://dx.doi.org/10.1002/jcb.25353.
    10.1002/jcb.25353
  21. Higuera, Gustavo A.; Fernandes, Hugo; Spitters, Tim W.G.M.; van de Peppel, Jeroen; Aufferman, Nils; Truckenmueller, Roman; Escalante, Maryana; et al. "Spatiotemporal proliferation of human stromal cells adjusts to nutrient availability and leads to stanniocalcin-1 expression in vitro and in vivo". Biomaterials 61 (2015): 190-202. http://dx.doi.org/10.1016/j.biomaterials.2015.05.017.
    10.1016/j.biomaterials.2015.05.017
  22. Ghebes, Corina Adriana; Kelder, Cindy; Schot, Thomas; Renard, Auke J.; Pakvis, Dean F. M.; Fernandes, Hugo; Saris, Daniel B.. "Anterior cruciate ligament- and hamstring tendon-derived cells: in vitro differential properties of cells involved in ACL reconstruction". Journal of Tissue Engineering and Regenerative Medicine 11 4 (2015): 1077-1088. http://dx.doi.org/10.1002/term.2009.
    10.1002/term.2009
  23. Le B; Fernandes H; Bouten C; Karperien M; van Blitterswijk C; de Boer J. "High throughput screening assay for the identification of compounds enhancing collagenous extracellular matrix production by ATDC5 cells.". (2015): http://europepmc.org/abstract/med/25604243.
    10.1089/ten.TEC.2014.0088
  24. Thakkar, Shraddha; Ghebes, Corina A.; Ahmed, Maqsood; Kelder, Cindy; van Blitterswijk, Clemens A.; Saris, Daniel; Fernandes, Hugo A. M.; Moroni, Lorenzo. "Mesenchymal stromal cell-derived extracellular matrix influences gene expression of chondrocytes". Biofabrication 5 2 (2013):
    10.1088/1758-5082/5/2/025003
  25. Barradas, Ana M. C.; Monticone, Veronica; Hulsman, Marc; Danoux, Charlene; Fernandes, Hugo; Birgani, Zeinab Tahmasebi; Barrere-de Groot, Florence; et al. "Molecular mechanisms of biomaterial-driven osteogenic differentiation in human mesenchymal stromal cells". Integrative Biology 5 7 (2013): 920-931.
    10.1039/c3ib40027a
  26. Doorn, Joyce; Fernandes, Hugo A. M.; Le, Bach Q.; van de Peppel, Jeroen; van Leeuwen, Johannes P. T. M.; De Vries, Margreet R.; Aref, Zeen; et al. "A small molecule approach to engineering vascularized tissue". Biomaterials 34 12 (2013): 3053-3063.
    10.1016/j.biomaterials.2012.12.037
  27. Prins HJ; Fernandes H; Rozemuller H; van Blitterswijk C; de Boer J; Martens AC. "Spatial distribution and survival of human and goat mesenchymal stromal cells on hydroxyapatite and ß-tricalcium phosphate.". (2012): http://europepmc.org/abstract/med/23255230.
    10.1002/term.1681
  28. Barradas, Ana M.C.; Yuan, Huipin; van der Stok, Johan; Le Quang, Bach; Fernandes, Hugo; Chaterjea, Anindita; Hogenes, Marieke C.H.; et al. "The influence of genetic factors on the osteoinductive potential of calcium phosphate ceramics in mice". Biomaterials 33 23 (2012): 5696-5705. http://dx.doi.org/10.1016/j.biomaterials.2012.04.021.
    10.1016/j.biomaterials.2012.04.021
  29. Barradas, Ana M.C.; Fernandes, Hugo A.M.; Groen, Nathalie; Chai, Yoke Chin; Schrooten, Jan; van de Peppel, Jeroen; van Leeuwen, Johannes P.T.M.; van Blitterswijk, Clemens A.; de Boer, Jan. "A calcium-induced signaling cascade leading to osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells". Biomaterials 33 11 (2012): 3205-3215. http://dx.doi.org/10.1016/j.biomaterials.2012.01.020.
    10.1016/j.biomaterials.2012.01.020
  30. Portalska, Karolina Janeczek; Leferink, Anne; Groen, Nathalie; Fernandes, Hugo; Moroni, Lorenzo; van Blitterswijk, Clemens; de Boer, Jan. "Endothelial Differentiation of Mesenchymal Stromal Cells". Plos One 7 10 (2012):
    10.1371/journal.pone.0046842
  31. Yuan, Huipin; Fernandes, Hugo; Habibovic, Pamela; de Boer, Jan; Barradas, Ana M. C.; de Ruiter, Ad; Walsh, William R.; van Blitterswijk, Clemens A.; de Bruijn, Joost D.. "'Smart' biomaterials and osteoinductivity". Nature Reviews Rheumatology 7 4 (2011): 1-1.
    10.1038/nrrheum.2010.210-c1
  32. Nandakumar, Anandkumar; Fernandes, Hugo; de Boer, Jan; Moroni, Lorenzo; Habibovic, Pamela; van Blitterswijk, Clemens A.. "Fabrication of Bioactive Composite Scaffolds by Electrospinning for Bone Regeneration". Macromolecular Bioscience 10 11 (2010): 1365-1373. http://dx.doi.org/10.1002/mabi.201000145.
    10.1002/mabi.201000145
  33. Fernandes, Hugo; Dechering, Koen; van Someren, Eugene; Steeghs, Ilse; Apotheker, Marion; Mentink, Anouk; van Blitterswijk, Clemens; de Boer, Jan. "Effect of Chordin-Like 1 on MC3T3-E1 and Human Mesenchymal Stem Cells". Cells Tissues Organs 191 6 (2010): 443-452.
    10.1159/000281825
  34. Fernandes, Hugo; Mentink, Anouk; Bank, Ruud; Stoop, Reinout; van Blitterswijk, Clemens; de Boer, Jan. "Endogenous Collagen Influences Differentiation of Human Multipotent Mesenchymal Stromal Cells". Tissue Engineering Part a 16 5 (2010): 1693-1702.
    10.1089/ten.tea.2009.0341
  35. Liu, Jun; Barradas, Ana; Fernandes, Hugo; Janssen, Frank; Papenburg, Bernke; Stamatialis, Dimitrios; Martens, Anton; van Blitterswijk, Clemens; de Boer, Jan. "In Vitro and In Vivo Bioluminescent Imaging of Hypoxia in Tissue-Engineered Grafts". Tissue Engineering Part C-Methods 16 3 (2010): 479-485.
    10.1089/ten.tec.2009.0278
  36. Teixeira, S.; Fernandes, H.; Leusink, A.; van Blitterswijk, C.; Ferraz, M. P.; Monteiro, F. J.; de Boer, J.. "In vivo evaluation of highly macroporous ceramic scaffolds for bone tissue engineering". Journal of Biomedical Materials Research Part a 93A 2 (2010): 567-575.
    10.1002/jbm.a.32532
  37. Yuan, Huipin; Fernandes, Hugo; Habibovic, Pamela; de Boer, Jan; Barradas, Ana M. C.; de Ruiter, Ad; Walsh, William R.; van Blitterswijk, Clemens A.; de Bruijn, Joost D.. "Osteoinductive ceramics as a synthetic alternative to autologous bone grafting". Proceedings of the National Academy of Sciences of the United States of America 107 31 (2010): 13614-13619.
    10.1073/pnas.1003600107
  38. Fernandes, Hugo; Dechering, Koen; Van Someren, Eugene; Steeghs, Ilse; Apotheker, Marion; Leusink, Anouk; Bank, Ruud; et al. "The Role of Collagen Crosslinking in Differentiation of Human Mesenchymal Stem Cells and MC3T3-E1 Cells". Tissue Engineering Part A 15 12 (2009): 3857-3867. http://dx.doi.org/10.1089/ten.tea.2009.0011.
    10.1089/ten.tea.2009.0011
  39. Siddappa, Ramakrishnaiah; Mulder, Winfried; Steeghs, Ilse; van de Klundert, Christine; Fernandes, Hugo; Liu, Jun; Arends, Roel; van Blitterswijk, Clemens; de Boer, Jan. "cAMP/PKA Signaling Inhibits Osteogenic Differentiation and Bone Formation in Rodent Models". Tissue Engineering Part A 15 8 (2009): 2135-2143. http://dx.doi.org/10.1089/ten.tea.2008.0512.
    10.1089/ten.tea.2008.0512
  40. Schop, Deborah; Janssen, Frank W.; van Rijn, Linda D.S.; Fernandes, Hugo; Bloem, Rolf M.; de Bruijn, Joost D.; van Dijkhuizen-Radersma, Riemke. "Growth, Metabolism, and Growth Inhibitors of Mesenchymal Stem Cells". Tissue Engineering Part A 15 8 (2009): 1877-1886. http://dx.doi.org/10.1089/ten.tea.2008.0345.
    10.1089/ten.tea.2008.0345
  41. Fernandes, Hugo; Moroni, Lorenzo; van Blitterswijk, Clemens; de Boer, Jan. "Extracellular matrix and tissue engineering applications". Journal of Materials Chemistry 19 31 (2009): 5474-5484.
    10.1039/b822177d
  42. Siddappa, Ramakrishnaiah; Fernandes, Hugo; Liu, Jun; van Blitterswijk, Clemens; de Boer, Jan. "The response of human mesenchymal stem cells to osteogenic signals and its impact on bone tissue engineering.". Current stem cell research & therapy 2 3 (2007): 209-20.
    10.2174/157488807781696267
  43. Teixeira, S.; Fernandes, H.M.; De Boer, J.; Ferraz, M.P.; Monteiro, F.J.. "Mesenchymal stem cell proliferation and morphological analysis on interconnected macroporous structures". Key Engineering Materials 330-332 II (2007): 1129-1132. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846317063&partnerID=MN8TOARS.
Newsletter article
  1. Susana Simões; Fernandes, Hugo; Lino da Silva Ferreira. "Recent advances on non viral CRISPR nano formulations for brain delivery and clinical approaches", ARRIGE (Association for responsible research and innovation in genome editing Newsletter), 2021, https://www.arrige.org/wp-content/uploads/2021/10/ARRIGE_newsletter_issue4.pdf.

Intellectual property

Patent
  1. Fernandes, Hugo; Ferreira, L; Vazão, H. 2016. "Differentiated cell population of endothelial cells derived from human pluripotent stem cells, composition system, kit and uses therefore".
Provisional application for patent
  1. 2015. "Functionalization of biopolymers with growth factor-binding peptides".
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2022/03/12 miRNAs e vesículas extracelulares: uma nova terapia no tratamento do síndrome metabólico, 18th Congresso Português de diabetes
Sociedade Portuguesa Diabetes
2021/10/25 Science and Stem Cells. Seminars about science and stem cells organized at Centro Escolar Cantanhede. During one week (1h/day) I had the chance to present our work and discuss with the students science and cell biology Science and Stem cells
Centro Escolar Cantanhede (Cantanhede)
2021/10/13 Stem Cell Seminar Celebrations Stem Cell Day 2021
Escola Secundária Infanta D. Maria (Coimbra)
2021/10/13 Stem Cell Seminar
Escola Básica da Ponte das Três Entradas (São Sebastião Feira)
2021/09/14 microRNA-modulated extracellular vesicles for Regenerative Medicine applications 1st Meeting Portuguese Society Extracellular Vesicles
I3S (Portugal)
2021/09/06 miRNA-engineered extracellular vesicles for Regenerative Medicine applications 31st Conference European Society Biomaterials
ESB (Porto, Portugal)
2021/06/10 miRNA-modified extracellular vesicles for wound regeneration 55th Anual Scientific Meeting
European Society for Clinical Investigation
2021/06/10 Extracellular vesicles as lncRNA-H19 carriers to the cardiovascular system Presented by Andreia Vilaça 55th Anual Scientific Meeting
European Society for Clinical Investigation
2020/12 Non-coding RNA-engineered extracellular vesicles for cardiac regeneration, 1st Workshop of the Portuguese Network on Extracellular Vesicles
Portuguese Network on Extracellular Vesicles (Online, Portugal)
2020/11/06 Harnessing the power of extracellular vesicles for wound regeneration 11th International Congress on Skin Ageing & Challenges 2020
(Porto (Virtual Meeting), Portugal)
2019/10/11 High-content screening identifies pro-survival microRNas 11th International Meeting of the Portuguese Society for stem cells and cell therapies
Faculty Pharmacy Lisbon (Portugal)
2019/05 Human cardiac stem cell therapy PhD Program in Health Sciences
Faculty Medicine, University Coimbra
2019/04/13 Tailoring Biomaterials for Tissue Engineering Seminar Master Course in Pharmaceutical Biotechnology
Faculty of Pharmacy, University Coimbra (Portugal)
2019/04 “Regenerative Medicine: from the bench to the bedside and stem cells and drug screening” Course on Advanced Therapies, PhD Program in Experimental Biology and Biomedicine
Center Neuroscience and Cell Biology (Portugal)
2019/04 Tailoring Biomaterials for Tissue Engineering” Master in Pharmaceutical Biotechnology
Faculty of Pharmacy, University Coimbra (Portugal)
2018 High-content screening identifies pro-survival microRNAs 29th Annual Meeting of the European Society of Biomaterials
European Society Biomaterials (Netherlands)
2018 Smart technologies to enable tissue regeneration IV National Meeting Biotechnology
Instituto Politécnico Coimbra (Portugal)
2018 CardioSTem Project MIT Portugal Annual Conference
(Portugal)
2018 Identification of pro survival microRNAs Curso de “CIÊNCIAS CARDIOVASCULARES” Programa de Doutoramento em Ciências da Saúde, da Faculdade de Medicina da Universidade de Coimbra
CNC.IBILI (Portugal)
2018 Stem Cells and Regenerative Medicine Invited
University Aveiro (Portugal)
2017 High-throughput screening identifies pro-survival microRNas 10th International Meeting of the Portuguese Society for stem cells and cell therapies
(Portugal)
2017 From a medical problem to a product: new avenues in the treatment of skeletal disorders III Ciclo de Conferências em Biotecnologia Medicinal e Farmacêutica
Universidade Beira Interior (Portugal)
2017 Cell therapies for cardiac repair: role of microRNAs on cell survival Stem Cell Symposium
Portuguese Society for stem cells and cell therapies (Portugal)
2017 Identification of microRNAs capable of enhancing cell survival: Heart Without Borders
(Portugal)
2017 Identification of microRNAs capable of enhancing cell survival Curso de “CIÊNCIAS CARDIOVASCULARES” Programa de Doutoramento em Ciências da Saúde, da Faculdade de Medicina da Universidade de Coimbra
CNC.IBILI (Portugal)
2017 Stem cells and drug screening MIT-Portugal, PhD Program Lectures
Instituto Superior Técnico - Universidade Lisboa (Portugal)
2017 Identification of microRNAs capable of enhancing cell survival Department of Physiology and cardiothoracic surgery, Faculty Medicine, University Porto
University Porto (Portugal)
2016 Cell therapies for cardiac repair: role of microRNAs on cell survival Curso de “CIÊNCIAS CARDIOVASCULARES” Programa de Doutoramento em Ciências da Saúde, da Faculdade de Medicina da Universidade de Coimbra
CNC.IBILI (Portugal)
2016 High-content screening identifica pro-survival microRNAs Institutional Seminars CNC
CNC.IBILI (Portugal)
2016 Identification of pro-survival microRNAs to improve cell survival Centro Hospitalar Universidade Coimbra
(Portugal)
2016 Stem cells and Drug Screening MIT-Portugal; PhD Program Lecturer
Instituto Superior Técnico, Universidade Lisboa (Portugal)
2015 a small molecule approach to engineering vascularised tissue th International Meeting of the Portuguese Society for stem cells and cell therapies
Portuguese Society for stem cells and cell therapies (Portugal)
2015 Stem cells and cell-material interactions Lecture Master Degree Biomedical Engineering
University Aveiro (Portugal)
2015 Stem cells and drug screening MIT-Portugal; PhD Program Lecture
Instituto Superior Técnico, Universidade de Lisboa (Portugal)
2015 Bioengineering strategies to modulate stem cell fate Institutional Seminar
CNC.IBILI (Portugal)
2015 Stem Cells and Clinical Applications: are we doing it right? UC-Biotech Seminars
CNC.IBILI (Portugal)
2013 Enabling technologies to control cell fate Invited Seminar Ferreira Lab
(Portugal)
2012 A novel player in angiogenesis Invited Seminar Dankers Lab
Technical University of Eindhoven (Netherlands)
2011 topographical library to control stem cell fate 3rd COST TD0903 meeting
(Romania)
2011 human mesenchymal stromal cells as pro-angiogenic releasing systems 4th International Conference on Tissue Engineering
(Greece)
2011 A novel player in angiogenesis Invited Lecture Ferreira Lab
(Portugal)
2011 Training mesenchymal stromal cells for tissue engineering applications University Munich Seminars
(Germany)
2009 Hidden talents of stem cells World Congress on Regenerative Medicine
(Germany)
2008 Role of collagen cross linking in osteogenic differentiation: 8th World Biomaterials Congress
(Netherlands)
2007 potential application of extracellular matrix proteins to control osteogenic differentiation of human mesenchymal stem cells 16th conference of the Netherlands Society for Biomaterials and Tissue Engineering
(Netherlands)
2007 potential application of extracellular matrix proteins to control osteogenic differentiation of human mesenchymal stem cells: 17th Annual meeting of the Dutch Society for Calcium and bone metabolism
(Netherlands)
2006 Role of extracellular matrix on osteogenic differentiation 5th conference of the Netherlands Society for Biomaterials and Tissue Engineering
(Netherlands)
2006 Role of extracellular matrix on osteogenic differentiation 16th Annual Meeting of the Dutch Society for Calcium and Bone metabolism
(Netherlands)
2003 Career options 5th Meeting of Applied Biology
Universidade Minho (Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2018/09 - Current Towards personalised beta-cell mass imaging in type 2 diabetes
Supervisor
CNC.IBILI, Portugal
2018/09 - Current Urine extracellular vesicles: a promising tool for Regenerative Medicine
Supervisor
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/09 - Current Exosomes as platforms to modulate cardiac regeneration
Co-supervisor
CNC.IBILI, Portugal

Universiteit Maastricht, Netherlands
2016/09 - Current A multi-approach platform to identify biomolecules for cardiac regeneration
Co-supervisor
CNC.IBILI, Portugal

Universiteit Maastricht, Netherlands
2016 - 2022/03 Extracellular vesicles as platforms for therapeutic microRNA delivery
Co-supervisor
Universidade de Coimbra, Portugal

Universiteit Maastricht, Netherlands
2018 - 2022/02/21 Extracellular Vesicles as Platforms for Therapeutic microRNA delivery
Co-supervisor
Universiteit Maastricht, Netherlands

Universidade de Coimbra, Portugal
2018/09 - 2019/09 Uncover the mechanism behind miRNA function on cell survival
Supervisor
Universidade de Coimbra Faculdade de Medicina, Portugal
2019 - 2019 High-Throughput screening for extracellular vesicle content modulation for cardiovascular application
Supervisor
Master
Georg-August-Universität Göttingen Universitätsmedizin, Germany
2018/02 - 2018/09 Mechanism of action of pro-survival microRNAs
Supervisor
CNC.IBILI, Portugal
2018/01 - 2018/09 Towards personalised beta-cell mass imaging in type 2 diabetes
Supervisor
CNC.IBILI, Portugal
2018 - 2018 Urine extracellular vesicles: waste or a powerful tool?
Supervisor
Universidade de Coimbra, Portugal
2014/04 - 2017/09 Improving hematopoietic stem cell expansion using small molecules
Supervisor
Postdoctoral Fellow, FCT Scholarship: SFRH/BPD/97286/2013 (Other)
CNC.IBILI, Portugal
2017 - 2017 The role of miRNAs on cell survival
Supervisor
Universidade de Coimbra, Portugal
2013/07 - 2016/12 Functionalized surfaces for ligament tissue engineering
Supervisor
Universiteit Twente, Netherlands
2012/03 - 2016/09 Means of accelerating tendon graft healing after ACL reconstruction
Supervisor
Universiteit Twente, Netherlands
2016 - 2016 Identification of microRNAs to promote cell survival for the treatment of ischemic diseases
Supervisor
Universidade de Coimbra, Portugal
2015 - 2015 Optimizing an high-throughput screening assay for hematopoietic stem cell expansion in co-culture with Wharton´s Jelly mesenchymal stem cells
Supervisor
Universidade de Coimbra, Portugal
2013/09 - 2014/02 Non-surgical tissue engineering approaches to sub-failure ligament and tendon injury repair
Co-supervisor
Rutgers The State University of New Jersey, United States
2014 - 2014 Functionalized surfaces stimulating tendon/ligament healing by activation of the TGFb1 signalling
Supervisor
Universiteit Twente, Netherlands
2014 - 2014 High-throughput screening to identify BMP-2 mimicking drugs
Supervisor
Universiteit Twente, Netherlands
2014 - 2014 Screening for small molecules that mimic TGF-b activation
Supervisor
Universiteit Twente, Netherlands
2013 - 2014 Bioassay development to identify pro-survival and pro-angiogenic compounds
Supervisor
Universiteit Twente, Netherlands
2013 - 2014 New technologies for the isolation and priming of bone marrow cells”
Supervisor
Universiteit Twente, Netherlands
2013 - 2014 High-throughput screening for tendon and ligament healing
Supervisor
Universiteit Twente, Netherlands

Universidade de Trás-os-Montes e Alto Douro, Portugal
2013/09 - 2013/10 Tendon and Ligament Engineering
Supervisor
Postdoctoral Fellow (Other)
Universiteit Twente, Netherlands
2013 - 2013 Crosstalk between mesenchymal stem cells and muscle, cartilage and bone cells in co-culture
Supervisor
Universiteit Twente, Netherlands
2013 - 2013 Influence of cell shape on cell fate decision
Supervisor
Universiteit Twente, Netherlands

Universidade do Minho, Portugal
2013 - 2013 Characterization of hamstring and anterior cruciate ligament cells
Supervisor
Universiteit Twente, Netherlands
2012 - 2012 The effect of cell shape on cell fate
Supervisor
Universiteit Twente, Netherlands
2012 - 2012 Characterization of anterior cruciate ligament derived cells
Supervisor
Universiteit Twente, Netherlands
2011 - 2011 The power of extracellular matrix
Co-supervisor
Universiteit Twente, Netherlands
2010 - 2010 Endothelial differentiation of mesenchymal stem cells
Co-supervisor
Universiteit Twente, Netherlands
2008 - 2008 Relation between hMSCs diffreentiation, cell shape and focal adhesion assembly
Co-supervisor
2007 - 2007 The effect of extracellular matrix recombinant proteins on osteogenic differentiation of human mesenchymal stem cells
Co-supervisor
Universiteit Twente, Netherlands

Event organisation

Event name
Type of event (Role)
Institution / Organization
2015 - Current Organisation of the weekly Seminars at UC-Biotech (2015)
Seminar (Member of the Organising Committee)
Universidade de Coimbra, Portugal
2001 - Current Organisation of the 3rd Meeting of Applied Biology. Contributed to the outline of the meeting. (2001)
2021/10/13 - 2021/10/13 Organization of the Stem Cell Day - together with other scientists we organized seminars at different schools in the Center Region of Portugal. (2021/10/13 - 2021/10/13)
Seminar (President of the Organising Committee)
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal
2021/09/17 - 2021/09/17 3rd Retreat of CIBB's Innovative Therapies Area. Annual meeting organized by CIBB thematic strand Innovative Therapies led by Lino Ferreira. The goal is to get together, share the latest scientific achievements, get to know new members and socialize in an informal manner. (2021/09/17)
Meeting (Member of the Organising Committee)
Centre for Innovative Biomedicine and Biotechnology, Portugal
2020/01/16 - 2020/01/16 Organisation of an in-site visit to high school students (Escola Secundária Moimenta da Beira). I delivered a lecture on stem cells and organised the visit to the different laboratories. (2020/01/16 - 2020/01/16) CNC.IBILI, Portugal
2019/10/25 - 2019/10/25 Organisation of an in-site visit to high school students (Colégio Nossa Senhora Assunção, Anadia). I delivered a lecture about stem cells and organised the visit to the different laboratories. (2019/10/25)

Event participation

Activity description
Type of event
Event name
Institution / Organization
2022/01 - Current Research in higher education: How and what for? A meeting organised by the General Council University of Coimbra to discuss Research in Higher Education.
Meeting
Research in higher education: How and what for?
2021/11 - Current Chair of a symposium entitled Extracellular Vesicles for Tissue Regeneration. I proposed the symposium and invited the Keynote speaker, Professor Eduardo Marban, Director, Cedars-Sinai Heart Institute (USA).
Congress
6th TERMIS World Congress
2021/06/11 - Current The first meeting of the consortium RESETageing, an EU-financed Twinning project with the University of Groningen and University of Maastricht (The Netherlands), and University Newcastle (UK).
Conference
1st RESETageing Conference
Universidade de Coimbra, Portugal
2019/02/27 - Current diálogos com cientistas - seminar about stem cells and cell therapy
Seminar
Cardiovascular Diseases and cell therapy
Escola Secundária Oliveira Bairro, Portugal
2019/02/22 - Current Conferencias na Escola - Engagement with high school students.
Seminar
Conferências na Escola
Escola Secundária Marques Castilho, Portugal
2019 - Current Outreaching activity for High-school students and professors.
Seminar
Células estaminais e Medicina Regenerativa
Instituto de Educação e Cidadania, Portugal
2018 - Current 1st Meeting on Vesicular Biology
Meeting
1st Meeting on Vesicular Biology
2017 - Current Diálogos de Verão com cientistas
Round table
Doenças Cardiovasculares
Instituto de Educação e Cidadania, Portugal
2016 - Current Mês da Ciência
Symposium
Células Estaminais e Terapias Celulares
Instituto Politécnico de Coimbra Escola Superior de Tecnologia da Saúde de Coimbra, Portugal
2016 - Current Curso avançado de células estaminais
Seminar
Curso avançado de células estaminais
Instituto de Educação e Cidadania, Portugal
2016 - Current 1st Meeting on Biomedical Research
Meeting
1st Meeting on Biomedical Research
2015 - Current Curso avançado de células estaminais
Seminar
Curso avançado de células estaminais
Instituto de Educação e Cidadania, Portugal
2013 - Current Advances in Tissue Regeneration
Symposium
Advances in Tissue Regeneration, November 2013, The Netherlands.
2012 - Current Poster Presentation: Cell sources for anterior cruciate ligament reconstruction
Conference
TERMIS International, Austria.
Universiteit Twente, Netherlands
2012 - Current Poster Presentation: hypoxia mimicking small molecules induce an angiogenic trophic profile in human mesenchymal stromal cells. (Travel Award)
Conference
TERMIS International, Austria.
2012 - Current Poster Presentation: hypoxia mimicking small molecules induce an angiogenic trophic profile in human mesenchymal stromal cells
Symposium
Cell Symposia: Angiogenesis, metabolic regulation and cancer biology, Belgium.
2011 - Current Poster Presentation: human mesenchymal stromal cells as pro-angiogenic drug release systems
Meeting
4th International Angiogenesis Meeting, The Netherlands.
Universiteit Twente, Netherlands
2011 - Current 20th conference of the Netherlands Society for Biomaterials and Tissue Engineering
Conference
20th conference of the Netherlands Society for Biomaterials and Tissue Engineering
2011 - Current 21st Annual Meeting of the Dutch Society for Calcium and Bone Metabolism
Meeting
21st Annual Meeting of the Dutch Society for Calcium and Bone Metabolism
2011 - Current High-Throughput screening – shaping a new research area
Workshop
High-Throughput screening – shaping a new research area
2009 - Current Gordon Research Conference in Vascular Cell Biology
Conference
Gordon Research Conference in Vascular Cell Biology
2008 - Current Poster Presentation: Investigating the role of collagen in osteogenic differentiation of human mesenchymal stem cells
Meeting
TERMIS EU Meeting, Portugal.
Universiteit Twente, Netherlands
2008 - Current Poster Presentation: Investigating the role of the extracellular matrix on differentiation of human mesenchymal stem cells and MC3T3 cells
Workshop
International bone and mineral research society workshop, Switzerland.
Universiteit Twente, Netherlands
2008 - Current Poster Presentation: Investigating the role of extracellular matrix on differentiation of human mesenchymal stem cells and MC3T3 cells
Conference
17th conference of the Netherlands Society for Biomaterials and Tissue Engineering, The Netherlands.
Universiteit Twente, Netherlands
2007 - Current Dutch Program for Tissue Engineering meeting
Meeting
Dutch Program for Tissue Engineering meeting
2007 - Current 1st Dutch Conference on Bio-Medical Engineering
Conference
1st Dutch Conference on Bio-Medical Engineering
2005 - Current 15th Annual Meeting of the Dutch Society for Calcium and Bone Metabolism
Meeting
15th Annual Meeting of the Dutch Society for Calcium and Bone Metabolism
2005 - Current iBME Meeting
Meeting
iBME Meeting
2005 - Current Dutch Symposium on Tissue Engineering
Symposium
Dutch Symposium on Tissue Engineering
2005 - Current Embryonic Stem Cells symposium, Hubrecht Laboratory, April 2005, The Netherlands.
Symposium
Embryonic Stem Cells symposium
Hubrecht Institute, Netherlands
2005 - Current International Workshop textbook Tissue Engineering
Workshop
International Workshop textbook Tissue Engineering
2004 - Current 13th conference of the Netherlands Society for Biomaterials and Tissue Engineering
Conference
13th conference of the Netherlands Society for Biomaterials and Tissue Engineering
2000 - Current 2nd Meeting of Applied Biology
Meeting
2nd Meeting of Applied Biology, University of Minho
Universidade do Minho, Portugal
1999 - Current 1st Meeting of Applied Biology
Meeting
1st Meeting of Applied Biology
Universidade do Minho, Portugal
2022/03/10 - 2022/03/11 12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies. Chair of the panel on Exosomes.
Meeting
12th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies
2021/10/15 - 2021/10/15 Stem Cell Day 2021 - event organized by the Portuguese Society Stem Cells and Cell Therapy in collaboration with Ciência Viva
Seminar
Sociedade Portuguesa de Células Estaminais e Terapia Celular, Portugal

Ciência Viva, Portugal
2019/12/19 - 2019/12/20 CIBB Meeting 2019 - meeting organised by CIBB to foster collaboration between its members. Chair of the session on Advanced Therapies
Meeting
CNC.IBILI, Portugal
2019/11 - 2019/11 Diálogos com cientistas - Colégio Nossa Senhora Assunção (Anadia) Lecture with high-school students about stem cells and cardiovascular diseases
2019/11 - 2019/11 Semana Ciência e da Tecnologia 2019 - lab tour to high-school students at UC-Biotech. Science and Technology week 2019
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2021/12/07 Tailoring of the cellular microenvironment to guide cell fate and functions for bone tissue engineering strategies
(Thesis) Main arguer
Diana Sofia Santiago Jesus (Master)
Universidade de Aveiro, Portugal
2021/11/29 mirnas in pericardial fluid and their role in cardiac fibrosis - conversations inside us and how they change our hearts
(Thesis) Main arguer
Francisco Ribeiro Coelho de Melo Costa (Master)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2021/04/06 Contribution of Aging and Senescence to Intervertebral Disc Degeneration
(Thesis) Main arguer
Emanuel Novais (PhD)
Universidade do Minho Escola de Medicina, Portugal
2021/03 Bioencapsulamento de células estaminais e endoteliais para criação de um novo modelo in vitro de ossificação endocondral
(Thesis) Main arguer
Inês de Jesus Fernandes (Master)
Universidade de Aveiro, Portugal
2021/01/20 Healthy ageing: the heart of the matter is outside of the heart.
(Thesis) Main arguer
Federica de Majo (PhD)
Universiteit Maastricht, Netherlands
2020/12/17 Investigating the therapeutic potential of extracellular vesicles from hiPSCs and hiPSC-derived cardiac cells for heart regeneration
(Thesis) Main arguer
Marta Rodrigues Oliveira (Master)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2018 3D hybrid scaffolds for Tissue Engineering
(Thesis) Main arguer
Sara Neves (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
2018 Towards the development of potency assays and 3D inflammation models to evaluate the regenerative potential of mesenchymal/stromal cell (MSC) and MSC-derived products
(Thesis) Main arguer
Raquel Cunha (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 Vascular organ-on-a-chip platforms for disease modeling
(Thesis) Arguer
João Ribas (PhD)
Universidade de Coimbra, Portugal
2017 Development of a new nanostructure scaffold for neural stem/progenitor cell transplantation
(Thesis) Main arguer
Tânia Vieira (PhD)
Universidade Nova de Lisboa, Portugal
2017 Microengineered 3D in vitro model of human pulmonary alveoli: curvatures influence on lung epithelial cells
(Thesis) Main arguer
Sara Vilabril (Master)
Universidade de Coimbra, Portugal

Universiteit Twente, Netherlands
2016 Bioengineering platforms to modulate the activity of smooth muscle cells derived from progeria-induced pluripotent stem cells
(Thesis) Arguer
Patrícia Pitrez (PhD)
Universidade do Minho, Portugal
2016 microRNA inhibitor screening: searching for angiogenesis modulators in human endothelial cells
(Thesis) Main arguer
Ricardo Abreu (Master)
Universidade de Coimbra, Portugal

Universiteit Maastricht, Netherlands
2015 Tissue-Engineering approaches to stress urinary incontinence using acellular urethra bioscaffolds
(Thesis) Main arguer
Irina Simões (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 Engineering the microenvironment of human umbilical cord blood hematopoietic stem/progenitor cells towards efficient megakaryocytic lineage differentiation and platelet production ex-vivo
(Thesis) Main arguer
Javad Hatami (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2014 Modulation of induced pluripotency by substrate rigidity
(Thesis) Main arguer
Heloísa Salguinho (Master)
Universidade de Coimbra, Portugal
2014 A soft lithography method for patterning calcium phosphate ceramics
(Thesis) Main arguer
Daniel Pereira (Master)
Universidade de Coimbra, Portugal

Universiteit Twente, Netherlands

Association member

Society Organization name Role
2020/02 - Current Portuguese Society of Diabetology
2019/10 - Current Portuguese Society of Stem Cells and Cell Therapy Board member (Secretary)
2009 - Current Member of the Portuguese Society of Stem Cells and Cellular Therapy National Coordinator of the section "Science and technology of Stem Cells"
2017/10 - 2019/10 Portuguese Society of Stem Cells and Cell Therapy Member and National Coordinator of the working group "Science and Technology of Stem cells"

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2022/03 - Current Lecture to the student enrolled in the PhD program Cardiovascular Sciences. Title: cardiovascular regenerative Medicine Universidade de Coimbra, Portugal
2021/11 - Current Extracellular Vesicles and Regenerative Medicine (Mestrado integrado) Universidade de Coimbra, Portugal
2021/04/07 - Current Lecture "Cardiovascular Regenerative Medicine" (Doutoramento) Universidade de Coimbra Faculdade de Medicina, Portugal
2019/10/02 - Current Lecturer Master Biomedical Engineering - Regenerative Medicine. Two (3h) classes on Adult Stem Cells and High-Throughput Screening. (Mestrado) Universidade de Coimbra, Portugal
2019 - Current Human cardiac stem cell therapy PhD Program in Health Sciences - Faculty of Medicine, University Coimbra, Portugal Universidade de Coimbra, Portugal
2018 - Current Lecturer Master Biomedical Engineering - Regenerative Medicine. Two (3h) classes on Adult Stem Cells and High-Throughput Screening. Master Biomedical Engineering (Mestrado) Universidade de Coimbra, Portugal
2013 - Current Organization/Responsible/Lecturer course Advanced Cell Biology (Bacharelato) Universiteit Twente, Netherlands
2013 - Current Organization/Responsible/Lecturer course Advanced Cell Biology (Mestrado) Universiteit Twente, Netherlands
2021/10 - 2021/12 Regenerative Medicine - Master Biomedical Engineering Master Biomedical Engineering (Mestrado integrado) Universidade de Coimbra, Portugal
2019/12/09 - 2019/12/09 Lecture "Biomaterials and stem cell-based therapies" Master Chemical Engineerting (Mestrado integrado) Universidade de Coimbra, Portugal
2019/01 - 2019/04 Organisation of the course on Biotechnology (Outros) Instituto de Educação e Cidadania, Portugal
2015 - 2018 Lecturer Doctoral Programme in Ageing and Chronic Diseases (Doutoramento) Universidade de Coimbra, Portugal
2014 - 2017 Lecturer at the Doctoral Program Experimental Biology and Medicine (Doutoramento) Universidade de Coimbra, Portugal
2005 - 2013 Lecturer for Master course in Advanced Cell Biology (Mestrado) Universiteit Twente, Netherlands
2005 - 2013 Lecturer Bachelor Course Advanced Cell Biology (Bacharelato) Universiteit Twente, Netherlands

Evaluation committee

Activity description
Role
Institution / Organization Funding entity
2020 - Current Expert for the evaluation of Research Project Action Medical Research
2020 - Current Expert for the evaluation of Research Project Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung
2019 - Current Expert for the evaluation of Research Project The Dunhill Medical Trust
2018 - Current Expert for the evaluation of Marie Sklodowska-Curie Individual Fellowships
Evaluator
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions
2016 - Current Expert for the evaluation of Grants
Evaluator
Agence nationale de la recherche, France Agence nationale de la recherche
2016 - Current Expert for the evaluation of Grant applications
Evaluator
The National Science Centre
2020/09 - 2020/11 Expert for the evaluation of Marie Sklodowska-Curie Individual Fellowships
Evaluator
European Commission, Belgium
2019/10 - 2019/11 Expert for the evaluation of Marie Sklodowska-Curie Individual Fellowships
Evaluator
European Commission
2017 - 2017 Expert for the evaluation of Marie Sklodowska-Curie Individual Fellowships
Evaluator
EU Framework Programme for Research and Innovation Marie Sklodowska-Curie Actions

Interview (newspaper / magazine)

Activity description Newspaper / Forum
2018 Ligação entre médicos e investigadores Jornal Associação Portuguesa Intervenção Cardiovascular
2011 Love in the lab - tissue engineers form creative alliance; UTNieuws
2007 Além fronteiras e ciência em Portugês - entrevista a cientistas Portugueses Revista Mundus
Distinctions

Award

2020 Scientific Employment Stimulus 2019
Fundação para a Ciência e a Tecnologia, Portugal
2012 Travel Award
Tissue Engineering and Regenerative Medicine International Society, United States
2011 Best Paper (2010-2011)
Dutch Bone and Mineral Society, Netherlands
2010 Science Factor
Universiteit Twente, Netherlands