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Identification

Personal identification

Full name
Joana Catarina da Silva Bravo

Citation names

  • Bravo, Joana

Author identifiers

Ciência ID
AA15-F362-062E
ORCID iD
0000-0002-8403-7235
Education
Degree Classification
2017 - 2023/05/15
Concluded
 Programa Graduado em Áreas da Biologia Básica e Aplicada (GABBA) (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Psychostimulants and neuroinflammation: finding critical players in the crosstalk between glial cells and neurons" (THESIS/DISSERTATION)
2017
Concluded
 Neurobiologia (Mestrado integrado)
Universidade do Porto Faculdade de Medicina, Portugal
 18
2010
Concluded
 Anatomia Patológica, Citológica e Tanatológica (Licenciatura)
Instituto Politécnico do Porto, Portugal
 15
Affiliation

Science

Category
Host institution 		Employer
2023/06/16 - Current Researcher (Research) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2015/04/15 - 2016 Researcher (Research) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/10/01 - 2015/12/31 Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2014/04/01 - 2014/12/31 Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2010/09/15 - 2013/09/30 Researcher (Research) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2023/09 - 2024/07 Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2022/09 - 2023/07 Invited Assistant (Polytechnic Teacher) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2021/11/01 - 2022/07/31 Invited Assistant (Polytechnic Teacher) Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
Projects

Contract

Designation Funders
2023/06/16 - 2024/12/31 Advanced therapeutic approaches in addiction: targeting neuroinflammation
PTDC/SAU-TOX/0067/2021
Post-doc
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2017/04 - 2017/12 Operant behavioral tasks for evaluation of cognition, anxiety, fear and other complex behaviours in animal models
NORTE-01-0145-FEDER-000008
Research Fellow
Concluded
2016/04 - 2017/03 Vulnerabilidade às drogas de abuso em ratos pré adolescentes: Interação entre a predisposição genética e os factores ambientais
IF/00753/2014/CP1241/CT0005
Research Fellow
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Concluded
2015/04 - 2015/09 Does social behavior during adolescence a reflex of adverse early experiences? Effects of both maternal separation and environmental enrichment
info:eu-repo/grantAgreement/FCT/COMPETE/132642/PT
Research Fellow
Universidade do Algarve Faculdade de Ciências e Tecnologia
Concluded
2010/09 - 2013/09 "Neuroprotecting mechanisms of carnitine in mitochondrial dysfunction", PTDC/SAU-OSM/100630/2008.
PTDC/SAU-OSM/100630/2008
Research Fellow
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
Concluded
Outputs

Publications

Book chapter
  1. Almeida AC; Drpic D; Okada N; Bravo J; Madureira M; Maiato H. "Functional Dissection of Mitosis Using Immortalized Fibroblasts from the Indian Muntjac, a Placental Mammal with Only Three Chromosomes.". In Methods in molecular biology (Clifton, N.J.). 2020.
    10.1007/978-1-0716-0219-5_16
Conference abstract
  1. Andrade, Elva Bonifacio; Magalhães, Ana; Puga, Ana; Costa, Madalena; Bravo, Joana; Portugal, Camila Cabral; Ribeiro, Adilia; et al. "AB009. A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection". 2020.
    Published • 10.21037/pm.2020.ab009
Conference poster
  1. Rodrigues, João; Bravo, Joana; Bonifácio Andrade, Elva; Lorga, Inês; Vieira, Rita; Azevedo, Maria; Magalhães, Ana; Bettencourt Relvas, João; Summavielle, Teresa. "Psychostimulantabuse and neuroinflammation: findingcritical players in the crosstalk betweenglial cells and neurons.". Paper presented in XVI EuropeanMeeting on Glial Cells in Health andDisease., 2023.
  2. Rodrigues, João; Bravo, Joana; Bonifácio Andrade, Elva; Canedo, Teresa; Azevedo, Maria; Summavielle, Teresa. "Regulation of CD47 expression byinterferon-gamma under chronicMethamphetamine exposure". Paper presented in IJUP 2023, 2023.
  3. Rodrigues, João; Bravo, Joana; Bonifácio Andrade, Elva; Azevedo, Maria; Summavielle, Teresa; Canedo, Teresa. "Microglia-Neuron crosstalk in chronicMethamphetamine exposure: regulation ofCD47 expression by interferon-gamma". Paper presented in FENS Regional Meeting 2023, 2023.
  4. Rodrigues, João; Bravo, Joana; Bonifácio Andrade, Elva; Canedo, Teresa; Azevedo, Maria; Summavielle, Teresa. "Microglia-Neuron crosstalk in chronicmethamphetamine exposure". Paper presented in VIISymposium of the Portuguese GliaNetwork, 2023.
  5. Soares, Joana; Lorga, Inês; Bravo, Joana; Summavielle, Teresa; Manuel Vilanova; Bonifácio Andrade, Elva. "Uncovering the microglia response during neonatal Group B Streptococcus meningitis". Paper presented in IJUP’23-16th Youth Research Meeting of the University of Porto, 2023.
  6. Soares, Joana; Lorga, Inês; Bravo, Joana; Summavielle, Teresa; Manuel Vilanova; Bonifácio Andrade, Elva. "Microglia response to neonatal bacterial meningitis". Paper presented in XLVIII Annual Meeting of the Portuguese Society for Immunology, 2022., 2023.
  7. Canedo, Teresa; Silva, Ana I.; Andrade, Elva B.; Almeida, Tiago O.; Pombinho, António R.; Maia, André F.; Bravo, Joana; et al. "Unveiling the mechanism of methamphetamine-induced neuroinflammarory response: focus on astrocyte to microglia glutamatergic signaling (Presented by T. Summavielle)". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  8. Canedo, T.; Silva, Ana I.; Andrade, Elva B.; Almeida, Tiago O.; Pombinho, António R.; Maia, André F.; Bravo, Joana; et al. "Unveiling the mechanism of methamphetamine-induced neuroinflammarory response: focus on astrocyte to microglia glutamatergic signaling". Paper presented in XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  9. João P Brás; Bravo, Joana; Summavielle, Teresa; Bettencourt Relvas, João; Màrio A. Barbosa; Santos, Susana G.; Maria Ines Almeida. "miR-342 as a mediator of microglia activation". Paper presented in 100 years of Microglia - International Symposium (Lausanne, Switzerland), 2019.
  10. Ribeiro, Inês; Bravo, Joana; Canedo, Teresa; Lopes, Cátia DF; Summavielle, Teresa. "Methamphetamine and neuroinflammation: unveiling the crosstalk between glial cells and neurons". Paper presented in XVI Meeting of Portuguese Society for Neuroscience, 2019.
  11. Bravo, Joana; Ribeiro, Inês; Canedo, Teresa; Lopes, Cátia DF; Summavielle, Teresa. "Methamphetamine and neuroinflammation: a crosstalk between glial cells and neurons". Paper presented in 6th Venusberg Meeting on Neuroinflammation, 2019.
  12. Bravo, Joana; Ribeiro, Inês; Canedo, Teresa; Lopes, Cátia DF; Summavielle, Teresa. "Psychostimulant abuse and neuroinflammation: a crosstalk between glial cells and neurons". Paper presented in i3S Annual Meeting, 2018.
Journal article
  1. Bravo, Joana. "Poster Presentations". Glia 71 S1 (2023): E993-E994. http://dx.doi.org/10.1002/glia.24419.
    Published • 10.1002/glia.24419
  2. Bravo J; Magalhães C; Andrade EB; Magalhães A; Summavielle T. "The impact of psychostimulants on central and peripheral neuro-immune regulation: a scoping review of cytokine profiles and their implications for addiction.". Frontiers in cellular neuroscience (2023): http://europepmc.org/abstract/med/37305435.
    10.3389/fncel.2023.1109611
  3. Bravo J; Ribeiro I; Terceiro AF; Andrade EB; Portugal CC; Lopes IM; Azevedo MM; et al. "Neuron-Microglia Contact-Dependent Mechanisms Attenuate Methamphetamine-Induced Microglia Reactivity and Enhance Neuronal Plasticity.". Cells (2022): http://europepmc.org/abstract/med/35159165.
    10.3390/cells11030355
  4. Soares NL; Paiva I; Bravo J; Queiroga CSF; Melo BF; Conde SV; Romão CC; Summavielle T; Vieira HLA. "Carbon Monoxide Modulation of Microglia-Neuron Communication: Anti-Neuroinflammatory and Neurotrophic Role.". Molecular neurobiology (2021): http://europepmc.org/abstract/med/34796462.
    10.1007/s12035-021-02643-z
  5. Canedo T; Portugal CC; Socodato R; Almeida TO; Terceiro AF; Bravo J; Silva AI; et al. "Astrocyte-derived TNF and glutamate critically modulate microglia activation by methamphetamine.". Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology (2021): http://europepmc.org/abstract/med/34400780.
    10.1038/s41386-021-01139-7
  6. Brás JP; Bravo J; Freitas J; Barbosa MA; Santos SG; Summavielle T; Almeida MI. "TNF-alpha-induced microglia activation requires miR-342: impact on NF-kB signaling and neurotoxicity.". Cell death & disease (2020): http://europepmc.org/abstract/med/32488063.
    10.1038/s41419-020-2626-6
  7. Andrade EB; Magalhães A; Puga A; Costa M; Bravo J; Portugal CC; Ribeiro A; et al. "A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection.". Nature communications (2018): http://europepmc.org/abstract/med/30087335.
    10.1038/s41467-018-05492-y
  8. Amorim, Manuela; Bravo, Joana; Silva, Ana Isabel; Juliana Alves, CecA­lia; Monteiro, Pedro RR; MagalhAEes, Ana; Summavielle, Teresa. "Repeated Exposure to Ketamine in Adolescent Rats Results in Persistent Anxiety in the Adulthood". Journal of Drug and Alcohol Research 07 01 (2018): 1-10. http://dx.doi.org/10.4303/jdar/236060.
    Published • 10.4303/jdar/236060
  9. Braz SO; Cruz A; Lobo A; Bravo J; Moreira-Ribeiro J; Pereira-Castro I; Freitas J; et al. "Expression of Rac1 alternative 3' UTRs is a cell specific mechanism with a function in dendrite outgrowth in cortical neurons.". (2017): http://europepmc.org/abstract/med/28274785.
    10.1016/j.bbagrm.2017.03.002
  10. Bravo, Joana. "Exploring cinnamic acid scaffold: development of promising neuroprotective lipophilic antioxidants". Med. Chem. Commun. (2015):
    10.1039/C5MD00018A
  11. Bravo, Joana. "Biology-oriented development of novel lipophilic antioxidants with neuroprotective activity". RSC Advances - Royal Society of Chemistry (2015):
    10.1039/c4ra15164j
  12. Bravo, Joana. "Acetyl-L-carnitine prevents methamphetamine-induced structural damage on endothelial cells via ILK related MMP-9 activity". Molecular Neurobiology (2014):
    10.1007/s12035-014-8973-5
  13. Bravo, Joana. "Neuroprotective Action of Acetyl-L-Carnitine on Methamphetamine-Induced Dopamine Release". American Journal of Neuroprotection and Neurodegeneration (2011):
    http://dx.doi.org/10.1166/ajnn.2011.1022
Preprint
  1. Canedo, Teresa; Portugal, Camila Cabral; Socodato, Renato; Bravo, Joana; Almeida, Tiago Oliveira; Magalhães, João D.; Guerra-Gomes, Sónia; et al. "Astrocyte-derived TNF and glutamate critically modulate microglia reactivity by methamphetamine". 2021. https://doi.org/10.1101/2021.02.22.432170.
    10.1101/2021.02.22.432170