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I graduated in Biochemistry from the University of Porto in 2005 and obtained a PhD degree in Pharmaceutical Sciences in 2009 from the Kings College London. Currently, I am an Assitant Researcher at LAQV-REQUIMTE - University of Porto. The main research line focuses on several aspects of iron biochemistry, most importantly on how blood serum protein post-translational modifications (oxidation and glycation) contribute to the dyshomeostasis of systemic iron transport observed in diabetes mellitus and hereditary hemochromatosis and the occurrence of non-transferrin-bound iron. I have also been collaborating in several projects for disease biomarker discovery, taking advantage of proficient knowledge regarding mass spectrometry and proteomics. I have ongoing collaborations with the three major hospitals in the Porto area (H. S. António, H. S. João and Instituto Português de Oncologia IPO-Porto). I am the co-author of 47 publications in international peer reviewed journals, accumulating over 1800 citations and an h-index of 15. Notably, international collaborations, both in the field of iron biochemistry and glycoproteomics, resulted in publications in high impact factor journals, Coord. Chem. Rev., Eur. Heart J., Nat. Cell Biol., Theranostics, and J. Exp. Clin. Cancer Res. I have also participated in several competitive founding research projects, being currently Principle Investigator (PI) of the eQuaNTI project, which aims at developing a new quantification assay for NTBI. I am an active part in academic activities at the University of Porto (UP), supervising MSc and BSc students and being a regular lecturer at several curricular units. I am Invited Auxiliary Professor of Bioinorganic Chemistry at the Faculty of Sciences-UP and Invited Auxiliary Professor of Biological Chemistry at Institute of Biomedical Sciences-UP. Finally, I am a co-founder of GlycoMatters, a biotech start-up company dedicated to the definition of Glycoprotein biomarkers and molecular targets, and the translation of such knowledge into precision medicine approaches.
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Identification

Personal identification

Full name
André Moreira Neto da Silva

Citation names

  • Silva, André
  • Silva, A. M. N.
  • Silva, A. M.
  • Silva, André M. N.
  • Silva, A.
  • da Silva, A.M.N.

Author identifiers

Ciência ID
8B17-285E-C0CE
ORCID iD
0000-0001-5554-7714
Google Scholar ID
HHmX1EkAAAAJ
Researcher Id
G-2295-2010
Scopus Author Id
26653803700

Email addresses

  • andre.silva@fc.up.pt (Professional)

Addresses

  • LAQV-REQUIMTE, Departamento de Química e Bioquímica, Faculdade de Ciências, Universidade do Porto. R. D. Manuel II, Apartado 55142, 4169-007, Porto, Porto, Portugal (Professional)

Websites

Knowledge fields

  • Exact Sciences - Chemical Sciences - Analytical Chemistry
  • Exact Sciences - Chemical Sciences - Inorganic Chemistry
  • Medical and Health Sciences - Clinical Medicine - Endocrinology and Metabolism
  • Natural sciences - Biological Sciences - Biochemical Research Methods
  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
French Beginner (A1) Beginner (A1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2010/01 - 2013/06
Concluded
 Post-doctoral (Pós-doutoramento)
Major in Mass Spectrometry; Proteomics; Protein Post-translational modifications
Universidade de Aveiro Centro de Espectrometria de Massa, Portugal
2006/02 - 2009/11
Concluded
 PhD in Pharmaceutical Sciences (Doctor of Philosophy)
King's College London, United Kingdom
"Chemical Nature of Non-Transferrin-Bound Iron" (THESIS/DISSERTATION)
 n/a
2000/09 - 2005/01
Concluded
 Bioquimica (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Isolation and Further Characterization of the New Eukaryotic Elongation Factor 1 A2 Binding Protein" (THESIS/DISSERTATION)
 16 points (in a 20 point scale)
1997/09 - 2000/07
Concluded
 Agrupamento 1 - Científico-Natural (Ensino secundário)
Major in Agrupamento Científico-Natural
Escola Secundária D. Dinis, Portugal
 18
Affiliation

Science

Category
Host institution 		Employer
2017/01/01 - Current Researcher (Research) REQUIMTE LAQV Porto, Portugal
2015/01/01 - 2016/12/31 Researcher (Research) REQUIMTE Unidade de Ciências Biomoleculares Aplicadas, Portugal
2013/06/01 - 2014/12/31 Researcher (Research) REQUIMTE, Portugal
2010/01/01 - 2013/05/31 Postdoc (Research) Universidade de Aveiro Centro de Espectrometria de Massa, Portugal
2004/10/01 - 2005/12/20 Research Assistant (Research) Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
2004/03/01 - 2004/08/15 Research Trainee (Research) Aarhus Universitet Center for Strukturel Biologi, Denmark
Aarhus Universitet Center for Strukturel Biologi, Denmark

Teaching in Higher Education

Category
Host institution 		Employer
2022/09/12 - 2023/02/12 Invited Assistant Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Others

Category
Host institution 		Employer
2019/06/01 - Current Startup Company - Founder/Partner GlycoMatters, Portugal
GlycoMatters, Portugal
Projects

Grant

Designation Funders
2010/01/01 - 2013/05 CHARACTERIZATION OF THE NON-ENZYMATIC MODIFICATIONS OCCURRING IN SERUM TRANSFERRIN: IMPLICATIONS FOR DIABETIC PATHOLOGY
SFRH//BPD/64296/2009
Universidade de Aveiro Unidade de Investigação de Química Orgânica Produtos Naturais e Agroalimentares, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Concluded
2006/01/01 - 2009/10 NON-TRANSFERRIN BOUND IRON: UNDERSTANDING THE CHEMICAL NATURE AND TOXICITY OF IRON(III) CITRATE SPECIES
SFHR/BD/22633/2005
 Fundação para a Ciência e a Tecnologia
Concluded

Contract

Designation Funders
2021/01/01 - 2025/12/31 Associated Laboratory for Green Chemistry - Clean Technologies and Processes
LA/P/0008/2020
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade de Aveiro, Portugal

Associação para a Inovação e Desenvolvimento da FCT, Portugal

Universidade de Évora, Portugal

Unidade de Investigação Vidro e Cerâmica para as Artes, Portugal

Universidade NOVA de Lisboa, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/02 - 2024/12/31 RESOLVE: Rational Design of Multivalent Glycocode-Inspired Nanovaccines for Gastric Cancer
PTDC/MED-OUT/2512/2021
Researcher
Instituto Português de Oncologia do Porto Francisco Gentil Centro de Investigação, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2023/03/01 - 2024/08/31 Keep fertility at advanced maternal age: on the track of uterine senescent cells
2022.04368.PTDC
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Universidade do Porto Faculdade de Medicina, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2023/01/02 - 2024/06/30 eQuaNTI: An enzymatic assay for the determination of blood serum non-transferrin-bound iron.
2022.06328.PTDC
Principal investigator
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2020/01/01 - 2023/12/31 Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos
UIDB/50006/2020
Research Fellow
REQUIMTE LAQV Porto, Portugal
 Governo da República Portuguesa Ministério da Ciência Tecnologia e Ensino Superior

Fundação para a Ciência e a Tecnologia
2019/01 - 2023/01 Polyphenols in Art
02/SAICT/2017
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Ongoing
2022/01/02 - 2022/12/31 IronIC | Infection and iron homeostasis: a new perspective for an old question
EXPL/BIA-BQM/1170/2021
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Ongoing
2019/01/01 - 2019/12/31 Laboratório Associado para a Química Verde - Tecnologias e Processos Limpos
UID/QUI/50006/2019
Research Fellow
REQUIMTE LAQV Porto, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Concluded
2016/04/01 - 2019/12/30 DESignBIOtecHealth - New Technologies for three Health Challenges of Modern Societies: Diabetes, Drug Abuse and Kidney Diseases
Norte-01-0145-FEDER-000024
Researcher
Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2016/06/01 - 2019/06/30 (Fe)rrying Plants to Prevent Chlorosis
PTDC/AGR-PRO/3515/2014
Researcher
Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal
 Fundação para a Ciência e Tecnologia - FCT
Ongoing
2013/06 - 2015/06 Nanochemistry
NORTE-07-0124-FEDER-000067
Researcher
Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
Outputs

Publications

Conference abstract
  1. Lopes, M.; Duarte, T.; Teles, M.; Mosteo, L; Chacim, S; Aguiar, E.; Pereira-Reis, J.; et al. "LOSS OF ERYTHROBLASTS IN ACUTE MYELOID LEUKEMIA CAUSES IRON REDISTRIBUTION WITH CLINICAL IMPLICATIONS". Paper presented in EHA Congress 2021 (European Heamatology Association Congress 2021), 2021.
    Accepted
  2. Alves, EA; Soares, JX; Silva, AM; Neves, JF; Cravo, SM; Rangel, M; Afonso, CM; et al. "identification of a complex mixture of opioids on krokodil street-like samples". 2016.
    10.1016/j.toxlet.2016.06.2039
Conference paper
  1. Miranda, Joana L. A.; Mesquita, Raquel B. R.; Leite, Andreia; Silva, André; Rangel, Maria; Rangel, António O. S. S.. "Study of 3,4-hydroxypyridinones functionalized beads for iron (III) determination in a microsequential injection solid phase spectrophotometry mode". 2018.
Conference poster
  1. Freitas, Rui; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Ferreira, Eduardo; Gaiteiro, Cristiana; et al. "Pre-clinical Validation of a Multivalent CD44 Glycoconjugate Vaccine for Cancer Immunotherapy". Paper presented in 1st Young Researcher's Day, 2023.
  2. Ferreira, Eduardo; Freitas, Rui; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Palmeira, Carlos; et al. "A Targeted and Self-Adjuvated PLGA MUC16-Tn Nanoglycovaccine Candidate for Cancer Immunotherapy". Paper presented in 1st Young Researcher's Day, 2023.
  3. Soares, Janine; Ferreira, Dylan; Miranda, Andreia; Relvas-Santos, Marta; Brandão, Andreia; Freitas, Rui; Ferreira, Eduardo; et al. "Glycosylation as a driver of Colorectal cancer aggressiveness". Paper presented in 1st Young Researchers¿s Day, 2023.
  4. Relvas-Santos, Marta; Peixoto, Andreia; Ferreira, Dylan; Lara Santos, Lúcio; Silva, André M. N.; Ferreira, José Alexandre. "Exploiting Glycoengineered Simple Cells and Targeted O-glycoproteomics Towards Bladder Cancer Neoantigens". Paper presented in 1st Young Researchers' Day, 2023.
  5. Silva, A. M. N.; Ramos, Eduardo; Porto, G; Rangel, M. Corresponding author: Silva, A. M. N.. "Albumin adducts with Glucose contribute to toxic iron in the blood serum". Paper presented in XXVII Encontro Luso-Galego de Química, 2023.
  6. Fonseca, Óscar; Couto, Carolina A; Ramos, Ana Sofia; Silva, André; Frederico Ferreira-da-Silva; Silva, Tânia; Gomes, Maria Salomé; Moreira, Ana C.. "The shift in iron metabolism: a new anti-inflammatory strategy?". Paper presented in 1st Symposium on Iron Metabolism and Cancer, 2023.
  7. Ramos, Eduardo; Porto, Graça; Rangel, Maria; Silva, André M. N.. Corresponding author: Ramos, Eduardo. "Understanding the role of transferrin post-translational modifications in serum iron binding in Hereditary Hemochromatosis". Paper presented in 18th YES Meeting, 2023.
  8. Ramos, Eduardo; Porto, Graça; Rangel, Maria; Silva, André M. N.. Corresponding author: Ramos, Eduardo. "Study of Glycation and Oxidation as naturally occurring Chemical Modifications in Serotransferrin". Paper presented in XXVIII Encontro Nacional da SPQ, 2023.
  9. Ramos, Ana Sofia; Fonseca, Óscar; Frederico Ferreira-da-Silva; Silva, André; Silva, Tânia; Gomes, Maria Salomé; Moreira, Ana C.. "The serum ¿iron-shift¿ during mycobacterial infection". Paper presented in SPI' 48 XLVIII Annual meeting of the Portugese Society of Immunology, 2023.
  10. Freitas, Rui; Miranda, Andreia; Ferreira, Dylan; Gaiteiro, Cristiana; Ferreira, Eduardo; Relvas-Santos, Marta; Soares, Janine; et al. "Production and pre-clinical evaluation of immunogenic CD44 glycoconjugates: setting the molecular bases for novel multivalent anti-cancer glycovaccines". Paper presented in Trabalho apresentado no XLVIII Annual Meeting of the Portuguese Society for Immunology, 2023.
  11. Ramos, Ana; Fonseca, Óscar; Frederico Ferreira-da-Silva; Silva, André; Silva, Tânia; Gomes, Maria Salomé; Moreira, Ana C.. Corresponding author: Ramos, Ana. "SPI' 48 XLVIII Annual meeting of the Portugese Society of Immunology". 2023.
  12. Rangel, Maria; Miranda, J. L. A.; Mesquita, Raquel B.R.; Leite, Andreia; Silva, A. M. N.; António O. S. S. Rangel. Corresponding author: Rangel, Maria. "NTBI determination using microsequential injection solid phase spectrometry in blood serum – proof of concept". Paper presented in European Iron Club Meeting 2022, 2022.
  13. Freitas, Rui; Relvas-Santos, Marta; Pereira Azevedo, Ana Rita ; Soares, Janine; Fernandes, Elisabete; Teixeira, Beatriz; Lara Santos, Lúcio; Silva, André M. N.; Ferreira, José Alexandre. "Single-pot enzymatic synthesis of cancer-associated MUC16 O-glycopeptides libraries and multivalent protein glycoconjugates: a step towards cancer glycovaccines. Trabalho apresentado no XLVII Annual Meeting of the Portuguese Society for Immunology". Paper presented in XLVII Annual Meeting of the Portuguese Society for Immunology, 2022.
  14. Freitas, Rui; Relvas-Santos, Marta; Pereira Azevedo, Ana Rita ; Soares, Janine; Fernandes, Elisabete; Teixeira, Beatriz; Santos, Lúcio; Silva, André M. N.; Ferreira, José Alexandre. "Single-pot enzymatic synthesis of cancer-associated Muc16 O-glycopeptides libraries and multivalent protein glycoconjugates: a step towards cancer glycovaccines". Paper presented in XLVII Annual Meeting of the Portuguese Society for Immunology, 2022.
  15. Freitas, Rui; Relvas-Santos, Marta; Pereira Azevedo, Ana Rita ; Soares, Janine; Fernandes, Elisabete; Beatriz Teixeira; Santos, Lúcio; Silva, André M. N.; Ferreira, José Alexandre. Corresponding author: Ferreira, José Alexandre. "Enzymatic synthesis of cancer-associated O-glycopeptides libraries and multivalent protein glycoconjugates: translating synthetic glycoepitopes into cancer glycovaccines". Paper presented in First Summer School in Biomedical Glycoscience, 2022.
  16. Freitas, Rui; Relvas-Santos, Marta; Azevedo, Rita; Soares, Janine; Beatriz Teixeira; Fernandes, Elisabete; Silva, André M. N.; Ferreira, José Alexandre; Santos, Lúcio. "Single pot enzymatic synthesis of cancer associated MUC16 O glycopeptide libraries and multivalent protein glycoconjugates: a step towards cancer glycovaccines. Trabalho apresentado no 4th I3S PhDay". Paper presented in 4th I3S PhDay: Break borders and build opportunities, 2021.
  17. Lopes, M.; Lemos, F.; Duarte, T.L.; Teles, M.J.; Silva, A. M. N.; Gonçalves, N.; Pereira-Reis, J.; et al. "Apotransferin in combination with induction chemotherapy protects against Escherichia coli infection in an acute myeloid leukemia mouse model". Paper presented in 31st European Congress of Clinical Microbiology & Infectious Diseases (ECMID 2021), 2021.
  18. Lopes, M.; Duarte, T.L.; Teles, M.J.; Mosteo, L.; Chacim, S.; Aguiar, E.; Pereira Reis, J.; et al. "Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications". Paper presented in 27th PORTO CANCER MEETING, 2021.
  19. Moreira, M.; Silva, A. M. N.; Guedes-Martins, L.; Saraiva, J.; Almeida, H.; Silva, E.; Matos, L.. "Using decellularized human uterine samples to assess the influence of the extracellular matrix on the age related decay on uterine function.". Paper presented in Encontro Investigação Jovem da Universidade do Porto (IJUP 2021), 2021.
  20. Abreu, D.; Teixeira, A. S.; Timoteo-Ferreira, F.; Rodrigues, A.R.; Silva, A. M. N.; Almeida, H.; Matos, L.; Silva, E.. "Reproductive ovarian ageing: a comparison with the liver". Paper presented in Encontro Investigação Jovem da Universidade do Porto (IJUP 2021), 2021.
  21. Rita Freitas; Marta Relvas-Santos; Elisabete Fernandes; Rita Azevedo; Silva, A. M. N.; Lúcio Lara Santos; José Alexandre Ferreira. "Single-pot enzymatic synthesis of short-chain MUC16 O-sialoglycopeptides and protein glycoconjugates for bioanalytical and biomedical applications". Paper presented in GLUPOR13 13th International Meeting of the Portuguese Carbohydrate Group, 2019.
  22. Cláudia Sofia Cardoso; Davide Carvalho; Maria Rangel; Silva, A. M. N.. "Characterization of transferrin glycation in type 1 Diabetes Mellitus". Paper presented in 8th BioIron Society Meeting, 2019.
  23. Andreia Peixoto; Elisabete Fernandes; Cristiana Gaiteiro; Luís Lima; Rita Azevedo; Janine Soares; Sofia Cotton; et al. "Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation". Paper presented in ICS 2018: 29th International Carbohydrate Symposium, 2018.
  24. Cláudia Sofia Cardoso; Davide Carvalho; Maria Rangel; Silva, A. M. N.. "Serum transferrin glycation and the occurrence of non-transferrin-bound iron in type 1 Diabetes Mellitus.". Paper presented in 12th IBCC - Inorganic and Bioinorganic Chemistry Conference of the Portuguese Chemistry Society, 2018.
  25. José Almeida; Andreia Leite; Luís Cunha-Silva; Maria Rangel; Ana Margarida Gomes Silva; Silva, A. M. N.. "Insights on the metal ion coordination of carboxyphenyl porphyrins and chlorins.". Paper presented in ISMEC 2018 - International Symposium on Metal Complexes, 2018.
  26. Miranda, J.L.A.; Mesquita, R.B.R.; Leite, A.; Silva, A. M. N.; Rangel, M.; Rangel, A.O.S.S.. "Study of 3,4–hydroxypyridinones functionalized beads for iron(III) determination in a microsequential injection solid phase spectrometry mode.". Paper presented in Analitica2018 - 9th meeting of the Division of Analytical Chemistry of the Portuguese Chemistry Society, 2018.
  27. Almeida, José; Andreia Leite; Silva, André; Luís Cunha-Silva; B. de Castro; Rangel, Maria; Silva, Ana M. G.. "Aiming at cancer: Structural and spectroscopic studies of new metalloporphyrins and metallochlorins". Paper presented in XXV Encontro Nacional da SPQ, 2017.
  28. Vinchi, F.; Porto, G.; Silva, A. M. N.; Sparla, R.; Vercelloti, G. M.; Belcher, J. D.; Fibach, E.; et al. "Elevated systemic heme and iron levels as risk factors for vascular dysfunction and atherosclerosis: evidence from B-thalassemia and hemochromatosis cohort studies.". Paper presented in 22nd Congress of the European Hematology Association, 2017.
  29. Rangel, M.; Coimbra, J.T.S.; Brás, N.F.; Fernandes, P.A.; Ramos, M. J.; Porto, G.; Silva, A. M. N.. "Non-enzymatic modifications of human serotransferrin and the dyshomeostasis of systemic iron transport.". Paper presented in XXV Encontro Nacional da Sociedade Portuguesa de Química (SPQ), 2017.
    10.13031/aim.20152189948
  30. Silva, A. M. N.; de Castro, M. M.; Oliveira, A. D. A.; Brás, N. F.; Coimbra, J.T.S.; Fernandes, P.A.; Ramos, M. J.; Rangel, M.. "Implications for iron-binding of human holo-transferrin glycation.". Paper presented in 11th Inorganic Chemistry Conference and 1st Meeting of the Inorganic and Bioinorganic Chemistry Division of the Portuguese Chemistry Society (SPQ), 2016.
  31. Moniz, T.; Mesquita, R. B. R.; Miranda, J. L. A.; Gomes, V.; Silva, A. M. N.; Rodrigues-Borges,; Rangel, A.O.S.S.; Rangel, M.. "3-Hydroxy-4-pyridinone functionalized with hydrophilic ethoxylated chains and their metal ion complexes.". Paper presented in 11th Inorganic Chemistry Conference and 1st Meeting of the Inorganic and Bioinorganic Chemistry Division of the Portuguese Chemistry Society (SPQ), 2016.
  32. Alves, E. A.; Soares, J. X.; Silva, A. M. N.; Neves, J. F.; Cravo, S. M.; Silva, A. M.; Rangel, M.; et al. "Identification of a complex mixture of opioids on krokodil street-like samples.". Paper presented in Eurotox 2016, 2016.
  33. Moreira, Ana S. P.; Coimbra, M.A.; Nunes, Fernando M.; Passos, Cláudia; Sónia Andreia Oliveira Santos; ARMANDO JORGE DOMINGUES SILVESTRE; da Silva, A.M.N.; Ranguel, M.; Domingues, M. Rosário M.. "Chlorogenic acid-arabinose hybrids as part of coffee melanoidin structures: evidences from a model system". Paper presented in 3rd International Congress on Cocoa Coffee and Tea (Aveiro, Portugal), 2015.
  34. Silva, A. M. N.; Sousa, P. R. H.; Coimbra, J. T. S.; Brás, N. F.; Vitorino, R.; Fernandes, P. A.; Ramos, M. J.; Rangel, M.; Domingues, P.. "Insight into lysine susceptibility to glycation in human serum transferrin and its relevance to transferrin-iron binding in diabetes.". Paper presented in The European Iron Club (EIC) Meeting 2014, 2014.
  35. Silva, A. M. N.; Marçal, S.; Vitorino, R.; Domingues, P.. "The oxidation of the alpha-amylase from Bacillus amyloliquefaciens: a study on a thermostable protein.". Paper presented in 4th EuPA (European Proteomics Association) meeting, 2010.
  36. Cheng, X.; Silva, A. M. N.; Hider, R. C.; Siow, R.; Mann, G. E.. "Impaired redox signalling in fetal endothelial cells in gestational diabetes: consequences for Nrf2/ARE mediated HO-1 expression and fetal programming.". Paper presented in 59th Annual conference of the British Microcirculation Society, 2009.
  37. Silva, A. M. N.; Kong, X. L.; Parkin, M. C.; Hider, R.C.. "Iron-Citrate Speciation in Aqueous Solutions: Implications for Biological Systems.". Paper presented in BioMetals Meeting, 2008.
  38. Silva, A. M. N.; Parkin, M. C.; Hider, R. C.. "Ferric Citrate Speciation and Interactions with Albumin in Aqueous Solutions: Implications for NTBI Speciation.". Paper presented in European Iron Club Meeting, 2007.
  39. Silva, A. M. N.; Hider, R. C.. "Characterization of Non-transferrin-bound iron: identification of iron citrate species and evaluation of their interaction with human serum albumin.". Paper presented in King's College London - Post-Graduate Student Symposium, 2007.
  40. Silva, A. M. N.; Hider, R. C.. "Characterization of Non-Transferrin-Bound Iron: Analysis of Iron - Citrate Solutions Using New Gel Permeation - Based Thin Layer Chromatography". Paper presented in King's College London - Post-Graduate Student Symposium, 2006.
  41. Silva, A. M. N.; Fernandes, P. A.; Ramos, M. J.. "Design of 2-cyclopentenone derivatives with enhanced NF-kB:DNA Binding Inhibitory Properties.". Paper presented in Quitel 2004 - 30º Congresso Internacional de Químicos Teóricos de Expressão Latina, 2004.
Journal article
  1. Freitas, Rui; Ferreira, Eduardo; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Santos, Beatriz; et al. "Targeted and Self-Adjuvated Nanoglycovaccine Candidate for Cancer Immunotherapy". ACS Nano (2024): http://dx.doi.org/10.1021/acsnano.3c12487.
    In press • 10.1021/acsnano.3c12487
  2. Freitas, Rui; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Ferreira, Eduardo; Gaiteiro, Cristiana; et al. "A multivalent CD44 glycoconjugate vaccine candidate for cancer immunotherapy". Journal of Controlled Release 367 (2024): 540-556. http://dx.doi.org/10.1016/j.jconrel.2024.01.065.
    Published • 10.1016/j.jconrel.2024.01.065
  3. Eduardo Ferreira; Dylan Ferreira; Marta Relvas-Santos; Rui Freitas; Janine Soares; Rita Azevedo; Luís Pedro Afonso; et al. "Aberrantly Glycosylated GLUT1 as a Poor Prognosis Marker in Aggressive Bladder Cancer". International Journal of Molecular Sciences (2024): https://www.mdpi.com/1422-0067/25/6/3462.
    10.3390/ijms25063462
  4. Freitas, Rui; Ferreira, Eduardo; Miranda, Andreia; Ferreira, Dylan; Relvas-Santos, Marta; Castro, Flávia; Santos, Beatriz; et al. "Targeted and Self-Adjuvated PLGA MUC16-Tn Nanoglycovaccine Candidate for Cancer Immunotherapy". ACS Nano (2024):
    Submitted
  5. Cotton, Sofia; Ferreira, Dylan; Relvas-Santos, Marta; Brandão, Andreia; Luis Afonso; Miranda, Andreia; Ferreira, Eduardo; et al. "E-selectin Affinity Glycoproteomics Reveals Neuroendocrine Proteins and the Secretin Receptor as a Poor Prognosis Signature in Colorectal Cancer". (2024):
    Submitted
  6. Amaral, Luísa M. P. F.; Moniz, Tânia; Silva, A. M. N.; Rangel, Maria. Corresponding author: Silva, A. M. N.. "Vanadium Compounds with Antidiabetic Potential". International Journal of Molecular Sciences 24 21 (2023): 15675. http://dx.doi.org/10.3390/ijms242115675.
    Published • 10.3390/ijms242115675
  7. Duarte, Tiago L.; Lopes, Marta; Oliveira, Mónica; Santos, Ana G.; Vasco, Catarina; Reis, Joana P.; Antunes, Ana Rita; et al. "Iron overload induces dysplastic erythropoiesis and features of myelodysplasia in Nrf2-deficient mice". Leukemia 38 1 (2023): 96-108. http://dx.doi.org/10.1038/s41375-023-02067-9.
    Published • 10.1038/s41375-023-02067-9
  8. Miranda, Joana L.A.; Mesquita, Raquel B.R.; Leite, Andreia; Silva, A. M. N.; Rangel, Maria; Rangel, António O.S.S.. Corresponding author: Rangel, António O.S.S.. "Non-transferrin-bound iron determination in blood serum using microsequential injection solid phase spectrometry– proof of concept". Talanta 257 (2023): 124345. http://dx.doi.org/10.1016/j.talanta.2023.124345.
    Published • 10.1016/j.talanta.2023.124345
  9. Gaiteiro, C.; Silva, A. M. N.; Ferreira, J.A.. "Glycoproteogenomics characterizes the CD44 splicing code associate with bladder cancer invasion.". Theranostics (2022): https://www.thno.org/ms/doc/3507/epub/67409k2/pubfile/thno_67409k2_1.pdf.
    Accepted • 10.7150/thno.67409
  10. Silva, A. M. N.; Rangel, Maria. Corresponding author: Silva, A. M. N.. "The (Bio)Chemistry of Non-Transferrin-Bound Iron". Molecules 27 6 (2022): 1784. http://dx.doi.org/10.3390/molecules27061784.
    10.3390/molecules27061784
  11. Barreira, Sérgio; Silva, André M. N.; Moutinho, Carla; Seo, Ean-Jeong; Hegazy, Mohamed-Elamir F.; Efferth, Thomas; Gomes, Lígia Rebelo. "Effect of Extraction Methodology on the Phytochemical Composition for Camelia sinensis “Powdered Tea Extracts” from Different Provenances". Beverages 8 1 (2022): 13. http://dx.doi.org/10.3390/beverages8010013.
    10.3390/beverages8010013
  12. Silva, André M.N.; Moniz, Tânia; de Castro, Baltazar; Rangel, Maria. Corresponding author: Silva, André M.N.. "Human transferrin: An inorganic biochemistry perspective". Coordination Chemistry Reviews 449 (2021): 214186. http://dx.doi.org/10.1016/j.ccr.2021.214186.
    10.1016/j.ccr.2021.214186
  13. Lopes, Marta; Duarte, Tiago L.; Teles, Maria J.; Mosteo, Laura; Chacim, Sérgio; Aguiar, Eliana; Pereira-Reis, Joana; et al. "Loss of erythroblasts in acute myeloid leukemia causes iron redistribution with clinical implications". Blood Advances 5 16 (2021): 3102-3112. http://dx.doi.org/10.1182/bloodadvances.2021004373.
    Published • 10.1182/bloodadvances.2021004373
  14. Peixoto, A.; Freitas, R.; Ferreira, D.; Relvas-Santos, M.; Paulo, P.; Cardoso, M.; Soares, J.; et al. "Metabolomics, Transcriptomics and Functional Glycomics Reveals Bladder Cancer Cells Plasticity and Enhanced Aggressiveness Facing Hypoxia and Glucose Deprivation". bioRxive (2021): https://www.biorxiv.org/content/10.1101/2021.02.14.431133v1.
    Submitted • 10.1101/2021.02.14.431133
  15. Peixoto, Andreia; Ferreira, Dylan; Azevedo, Rita; Freitas, Rui; Fernandes, Elisabete; Relvas-Santos, Marta; Gaiteiro, Cristiana; et al. "Glycoproteomics identifies HOMER3 as a potentially targetable biomarker triggered by hypoxia and glucose deprivation in bladder cancer". Journal of Experimental & Clinical Cancer Research 40 1 (2021): 191. http://dx.doi.org/10.1186/s13046-021-01988-6.
    In press • 10.1186/s13046-021-01988-6
  16. Ferreira, José Alexandre; Relvas-Santos, Marta; Peixoto, Andreia; Silva, André M.N.; Santos, Lúcio Lara. "Glycoproteogenomics: Setting the Course for Next Generation Cancer Neoantigens Discovery for Cancer Vaccines". Genomics, Proteomics & Bioinformatics (2021): http://dx.doi.org/10.1016/j.gpb.2021.03.005.
    Open access • In press • 10.1016/j.gpb.2021.03.005
  17. Loureiro, Daniela R. P.; Soares, José X.; Maia, Ana; Silva, André M. N.; Rangel, Maria; Azevedo, Carlos M. G.; Hansen, Steffen V.; et al. "One-Pot Synthesis of Xanthone by Carbonylative Suzuki Coupling Reaction". ChemistrySelect 6 18 (2021): 4511-4514. http://dx.doi.org/10.1002/slct.202101394.
    Accepted • 10.1002/slct.202101394
  18. Vinchi, Francesca; Sparla, Richard; Passos, Sara T.; Sharma, Richa; Vance, S. Zebulon; Zreid, Hala S.; Juaidi, Hesham; et al. "Vasculo-toxic and pro-inflammatory action of unbound haemoglobin, haem and iron in transfusion-dependent patients with haemolytic anaemias". British Journal of Haematology 193 3 (2021): 637-658. http://dx.doi.org/10.1111/bjh.17361.
    Published • 10.1111/bjh.17361
  19. Cotton, Sofia; Ferreira, Dylan; Soares, Janine; Peixoto, Andreia; Relvas-Santos, Marta; Azevedo, Rita; Piairo, Paulina; et al. "Target Score - A Proteomics Data Selection Tool Applied to Esophageal Cancer Identifies GLUT1-Sialyl Tn Glycoforms as Biomarkers of Cancer Aggressiveness". International Journal of Molecular Sciences 22 4 (2021): 1664. http://dx.doi.org/10.3390/ijms22041664.
    10.3390/ijms22041664
  20. Sérgio Barreira; Carla Moutinho; André M.N. Silva; José Neves; Ean-Jeong Seo; Mohamed-Elamir F. Hegazy; Thomas Efferth; Lígia Rebelo Gomes. "Phytochemical characterization and biological activities of green tea (Camellia sinensis) produced in the Azores, Portugal". Phytomedicine Plus 1 1 (2021): 100001-100001. https://doi.org/10.1016/j.phyplu.2020.100001.
    10.1016/j.phyplu.2020.100001
  21. Freitas, Rui; Relvas-Santos, Marta; Azevedo, Rita; Soares, Janine; Fernandes, Elisabete; Teixeira, Beatriz; Santos, Lúcio Lara; Silva, André M. N.; Ferreira, José Alexandre. "Single-pot enzymatic synthesis of cancer-associated MUC16 O-glycopeptide libraries and multivalent protein glycoconjugates: a step towards cancer glycovaccines". New Journal of Chemistry (2021): http://dx.doi.org/10.1039/d0nj06021f.
    10.1039/d0nj06021f
  22. Vinchi, Francesca; Porto, Graca; Simmelbauer, Andreas; Altamura, Sandro; Passos, Sara T; Garbowski, Maciej; Silva, André M N; et al. "Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction". European Heart Journal 41 28 (2020): 2681-2695. http://dx.doi.org/10.1093/eurheartj/ehz112.
    Published • 10.1093/eurheartj/ehz112
  23. Mendes, S.; Timóteo-Ferreira, F.; Soares, A.I.; Rodrigues, A.R.; Silva, A.M.N.; Silveira, S.; Matos, L.; et al. "Age-related oxidative modifications to uterine albumin impair extravillous trophoblast cells function". Free Radical Biology and Medicine 152 (2020): 313-322. http://dx.doi.org/10.1016/j.freeradbiomed.2020.03.020.
    Published • 10.1016/j.freeradbiomed.2020.03.020
  24. Fernandes, Elisabete; Freitas, Rui; Ferreira, Dylan; Soares, Janine; Azevedo, Rita; Gaiteiro, Cristiana; Peixoto, Andreia; et al. "Nucleolin-Sle A Glycoforms as E-Selectin Ligands and Potentially Targetable Biomarkers at the Cell Surface of Gastric Cancer Cells". Cancers 12 4 (2020): 861. http://dx.doi.org/10.3390/cancers12040861.
    Published • 10.3390/cancers12040861
  25. Almeida, José; Fortuna, Maria E.; Pricop, Lucia; Lobiuc, Andrei; Leite, Andreia; Silva, André M. N.; Monteiro, Rodrigo P.; et al. "(Aminophenyl)porphyrins as precursors for the synthesis of porphyrin-modified siloxanes". Journal of Porphyrins and Phthalocyanines 23 09 (2019): 1001-1012. http://dx.doi.org/10.1142/s1088424619500573.
    Published • 10.1142/s1088424619500573
  26. Moniz, Tânia; Cunha-Silva, Luís; Mesquita, Raquel B.R.; Miranda, Joana L.A.; Silva, André M.N.; Silva, Ana M.G.; Rangel, António O.S.S.; de Castro, Baltazar; Rangel, Maria. "New hydrophilic 3-hydroxy-4-pyridinone chelators with ether-derived substituents: Synthesis and evaluation of analytical performance in the determination of iron in waters". Polyhedron 160 (2019): 145-156. http://dx.doi.org/10.1016/j.poly.2018.12.005.
    Published • 10.1016/j.poly.2018.12.005
  27. Rangel, Maria; Moniz, Tânia; Silva, André; Leite, Andreia. "Tuning the Anti(myco)bacterial Activity of 3-Hydroxy-4-pyridinone Chelators through Fluorophores". Pharmaceuticals 11 4 (2018): 110. http://dx.doi.org/10.3390/ph11040110.
    Published • 10.3390/ph11040110
  28. Carrascal, M.A.; Silva, M.; Ferreira, J.A.; Azevedo, R.; Ferreira, D.; Silva, A.M.N.; Ligeiro, D.; et al. "A functional glycoproteomics approach identifies CD13 as a novel E-selectin ligand in breast cancer". Biochimica et Biophysica Acta (BBA) - General Subjects 1862 9 (2018): 2069-2080. http://dx.doi.org/10.1016/j.bbagen.2018.05.013.
    Published • 10.1016/j.bbagen.2018.05.013
  29. Silva, André M.N.; Coimbra, João T.S.; Castro, Maria M.; Oliveira, Ângela; Brás, Natércia F.; Fernandes, Pedro A.; Ramos, Maria J.; Rangel, Maria. Corresponding author: Silva, André M.N.. "Determining the glycation site specificity of human holo-transferrin". Journal of Inorganic Biochemistry 186 (2018): 95-102. http://dx.doi.org/10.1016/j.jinorgbio.2018.05.016.
    Published • 10.1016/j.jinorgbio.2018.05.016
  30. Zhang, Haiying; Freitas, Daniela; Kim, Han Sang; Fabijanic, Kristina; Li, Zhong; Chen, Haiyan; Mark, Milica Tesic; et al. "Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation". Nature Cell Biology 20 3 (2018): 332-343. http://dx.doi.org/10.1038/s41556-018-0040-4.
    Published • 10.1038/s41556-018-0040-4
  31. Azevedo, Rita; Silva, André M.N.; Reis, Celso A.; Santos, Lúcio Lara; Ferreira, José Alexandre. "In silico approaches for unveiling novel glycobiomarkers in cancer". Journal of Proteomics 171 (2018): 95-106. http://dx.doi.org/10.1016/j.jprot.2017.08.004.
    Published • 10.1016/j.jprot.2017.08.004
  32. Almeida, José; Silva, André M. N.; Rebelo, Susana L. H.; Cunha-Silva, Luís; Rangel, Maria; de Castro, Baltazar; Leite, Andreia; Silva, Ana M. G.. "Synthesis and coordination studies of 5-(4'-carboxyphenyl)-10,15,20-tris(pentafluorophenyl)porphyrin and its pyrrolidine-fused chlorin derivative". New Journal of Chemistry 42 10 (2018): 8169-8179. http://dx.doi.org/10.1039/c7nj05165d.
    Published • 10.1039/c7nj05165d
  33. Soares, José Xavier; Alves, Emanuele Amorim; Silva, André M. N.; de Figueiredo, Natália Guimarães; Neves, João F.; Cravo, Sara Manuela; Rangel, Maria; et al. "Street-Like Synthesis of Krokodil Results in the Formation of an Enlarged Cluster of Known and New Morphinans". Chemical Research in Toxicology 30 8 (2017): 1609-1621. http://dx.doi.org/10.1021/acs.chemrestox.7b00126.
    Published • 10.1021/acs.chemrestox.7b00126
  34. Cotton, Sofia; Azevedo, Rita; Gaiteiro, Cristiana; Ferreira, Dylan; Lima, Luís; Peixoto, Andreia; Fernandes, Elisabete; et al. "Targeted O-glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced-stage bladder tumours". Molecular Oncology 11 8 (2017): 895-912. http://dx.doi.org/10.1002/1878-0261.12035.
    Published • 10.1002/1878-0261.12035
  35. Almeida, José; Aguiar, António; Leite, Andreia; Silva, André M. N.; Cunha-Silva, Luís; de Castro, Baltazar; Rangel, Maria; et al. "1,3-Dipolar cycloadditions with meso-tetraarylchlorins – site selectivity and mixed bisadducts". Organic Chemistry Frontiers 4 4 (2017): 534-544. http://dx.doi.org/10.1039/c6qo00771f.
    Published • 10.1039/c6qo00771f
  36. Peixoto, Andreia; Fernandes, Elisabete; Gaiteiro, Cristiana; Lima, Luís; Azevedo, Rita; Soares, Janine; Cotton, Sofia; et al. "Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension". Oncotarget 7 39 (2016): 63138-63157. http://dx.doi.org/10.18632/oncotarget.11257.
    Published • 10.18632/oncotarget.11257
  37. Rebelo, Susana; Silva, André; Medforth, Craig; Freire, Cristina. "Iron(III) Fluorinated Porphyrins: Greener Chemistry from Synthesis to Oxidative Catalysis Reactions". Molecules 21 4 (2016): 481. http://dx.doi.org/10.3390/molecules21040481.
    Published • 10.3390/molecules21040481
  38. Mesquita, Raquel B.R.; Moniz, Tânia; Miranda, Joana L.A.; Gomes, Vânia; Silva, André M.N.; Rodriguez-Borges, J.E.; Rangel, António O.S.S.; Rangel, Maria. "Synthesis and characterization of a 3-hydroxy-4-pyridinone chelator functionalized with a polyethylene glycol (PEG) chain aimed at sequential injection determination of iron in natural waters". Polyhedron 101 (2015): 171-178. http://dx.doi.org/10.1016/j.poly.2015.09.015.
    Published • 10.1016/j.poly.2015.09.015
  39. Moreira, Ana S.P.; Coimbra, Manuel A.; Nunes, Fernando M.; Passos, Cláudia P.; Santos, Sónia A.O.; Silvestre, Armando J.D.; Silva, André M.N.; Rangel, Maria; Domingues, M. Rosário M.. "Chlorogenic acid–arabinose hybrid domains in coffee melanoidins: Evidences from a model system". Food Chemistry 185 (2015): 135-144. http://dx.doi.org/10.1016/j.foodchem.2015.03.086.
    Published • 10.1016/j.foodchem.2015.03.086
  40. Queirós, Carla; Leite, Andreia; G. M. Couto, Maria; Cunha-Silva, Luís; Barone, Giampaolo; de Castro, Baltazar; Rangel, Maria; M. N. Silva, André; M. G. Silva, Ana. Corresponding author: M. G. Silva, Ana. "The Influence of the Amide Linkage in the FeIII-Binding Properties of Catechol-Modified Rosamine Derivatives (corresponding author)". Chemistry - A European Journal 21 44 (2015): 15692-15704. http://dx.doi.org/10.1002/chem.201502093.
    Published • 10.1002/chem.201502093
  41. Aguiar, António; Leite, Andreia; Silva, André M. N.; Tomé, Augusto C.; Cunha-Silva, Luís; de Castro, Baltazar; Rangel, Maria; Silva, Ana M. G.. "Isoxazolidine-fused meso-tetraarylchlorins as key tools for the synthesis of mono- and bis-annulated chlorins". Organic & Biomolecular Chemistry 13 26 (2015): 7131-7135. http://dx.doi.org/10.1039/c5ob00800j.
    Published • 10.1039/c5ob00800j
  42. Silva, André M. N.; Aguiar, António; Balula, Salete S.; Silva, Ana M. G.; Rangel, Maria. Corresponding author: Silva, André M. N.. "Characterization of a µ-oxo-bridged diiron porphyrin by ESI-LTQ-Orbitrap-MS (corresponding author)". Journal of Mass Spectrometry 49 8 (2014): 763-765. http://dx.doi.org/10.1002/jms.3405.
    Published • 10.1002/jms.3405
  43. Silva, André M. N.; Sousa, Paulo R. H.; Coimbra, João T. S.; Brás, Natércia F.; Vitorino, Rui; Fernandes, Pedro A.; Ramos, Maria J.; et al. Corresponding author: Silva, André M. N.. "The glycation site specificity of human serum transferrin is a determinant for transferrin's functional impairment under elevated glycaemic conditions (corresponding author)". Biochemical Journal 461 1 (2014): 33-42. http://dx.doi.org/10.1042/bj20140133.
    Published • 10.1042/bj20140133
  44. Gouveia, Duarte D.; Silva, André M.N.; Vitorino, Rui; Domingues, M. Rosário M.; Domingues, Pedro. "Efficiency of Trypsin Digestion for Mass-Spectrometry-Based Identification and Quantification of Oxidized Proteins: Evaluation of the Digestion of Oxidized Bovine Serum Albumin". European Journal of Mass Spectrometry 20 3 (2014): 271-278. http://dx.doi.org/10.1255/ejms.1279.
    Published • 10.1255/ejms.1279
  45. Rangel, Maria; Leite, Andreia; Silva, André; de Castro, Baltazar; Schlindwein, Walkiria; Murphy, Loretta. "EPR and XANES studies of anaerobic photolysis of iso-propilpyridinecobaloxime: Elucidation of the reactivity of the Co(II) primary product". Journal of Organometallic Chemistry 760 (2014): 11-18. http://dx.doi.org/10.1016/j.jorganchem.2014.01.033.
    Published • 10.1016/j.jorganchem.2014.01.033
  46. Aguiar, António; Ribeiro, Susana; Silva, André M.N.; Cunha-Silva, Luís; de Castro, Baltazar; Silva, Ana M.G.; Balula, Salete S.. "An efficient eco-sustainable oxidative desulfurization process using µ-oxo-bridged Fe(III) complex of meso-tetrakis(pentafluorophenyl)porphyrin". Applied Catalysis A: General 478 (2014): 267-274. http://dx.doi.org/10.1016/j.apcata.2014.04.002.
    Published • 10.1016/j.apcata.2014.04.002
  47. Rangel, Maria; Leite, Andreia; Silva, André M. N.; Moniz, Tânia; Nunes, Ana; Amorim, M. João; Queirós, Carla; et al. "Distinctive EPR signals provide an understanding of the affinity of bis-(3-hydroxy-4-pyridinonato) copper(ii) complexes for hydrophobic environments". Dalton Trans. 43 25 (2014): 9722-9731. http://dx.doi.org/10.1039/c4dt00642a.
    Published • 10.1039/c4dt00642a
  48. Silva, André M.N.; Vitorino, Rui; Domingues, M.Rosário M.; Spickett, Corinne M.; Domingues, Pedro. "Post-translational Modifications and Mass Spectrometry Detection". Free Radical Biology and Medicine 65 (2013): 925-941. http://dx.doi.org/10.1016/j.freeradbiomed.2013.08.184.
    Published • 10.1016/j.freeradbiomed.2013.08.184
  49. Silva, André M.N.; Marçal, Susana L.; Vitorino, Rui; Domingues, Maria R.M.; Domingues, Pedro. "Characterization of in vitro protein oxidation using mass spectrometry: A time course study of oxidized alpha-amylase". Archives of Biochemistry and Biophysics 530 1 (2013): 23-31. http://dx.doi.org/10.1016/j.abb.2012.12.010.
    Published • 10.1016/j.abb.2012.12.010
  50. Silva, André Moreira Neto; Borralho, Ana Carolina; Pinho, Sónia Andreia; Domingues, M. Rosário M.; Domingues, Pedro. "Cross-oxidation of angiotensin II by glycerophosphatidylcholine oxidation products". Rapid Communications in Mass Spectrometry 25 10 (2011): 1413-1421. http://dx.doi.org/10.1002/rcm.5006.
    Published • 10.1002/rcm.5006
  51. Hider, R.C.; Silva, A.M.N.; Podinovskaia, M.; Ma, Yongmin. "Monitoring the efficiency of iron chelation therapy: the potential of nontransferrin-bound iron". Annals of the New York Academy of Sciences 1202 1 (2010): 94-99. http://dx.doi.org/10.1111/j.1749-6632.2010.05573.x.
    Published • 10.1111/j.1749-6632.2010.05573.x
  52. Silva, Andre M.N.; Hider, Robert C.. "Influence of non-enzymatic post-translation modifications on the ability of human serum albumin to bind iron". Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1794 10 (2009): 1449-1458. http://dx.doi.org/10.1016/j.bbapap.2009.06.003.
    Published • 10.1016/j.bbapap.2009.06.003
  53. Silva, Andre M. N.; Kong, Xiaole; Hider, Robert C.. "Determination of the pKa value of the hydroxyl group in the a-hydroxycarboxylates citrate, malate and lactate by 13C NMR: implications for metal coordination in biological systems". BioMetals 22 5 (2009): 771-778. http://dx.doi.org/10.1007/s10534-009-9224-5.
    Published • 10.1007/s10534-009-9224-5
  54. Silva, Andre M. N.; Kong, XiaoLe; Parkin, Mark C.; Cammack, Richard; Hider, Robert C.. "Iron(iii) citrate speciation in aqueous solution". Dalton Transactions 40 (2009): 8616-8625. http://dx.doi.org/10.1039/b910970f.
    Published • 10.1039/b910970f
  55. Fernandes, Pedro A.; Cruz, Ana I.S.; Maia, Ana R.R.; Almeida, André A.S.; da Silva, André M.N.; Silva, Bruno F.B.; Ribeiro, Carla M.S.; et al. "Design of 2-cyclopentenone derivatives with enhanced NF-kB: DNA binding inhibitory properties". Journal of Molecular Structure: THEOCHEM 685 1-3 (2004): 73-82. http://dx.doi.org/10.1016/j.theochem.2004.06.027.
    Published • 10.1016/j.theochem.2004.06.027
Preprint
  1. Peixoto, Andreia; Ferreira, Dylan; Miranda, Andreia; Relvas-Santos, Marta; Freitas, Rui; Veth, Tim S.; Brandão, Andreia; et al. "Multilevel Plasticity and Altered Glycosylation Drive Aggressiveness in Hypoxic and Glucose-Deprived Bladder Cancer Cells". 2023. http://dx.doi.org/10.1101/2023.10.21.561355.
    10.1101/2023.10.21.561355
Thesis / Dissertation
  1. Silva, A. M. N.. "Chemical Nature of Non-Transferrin-Bound Iron". PhD, King's College London, 2009.
  2. Silva, A. M. N.. "Isolation and Further Characterization of the New Eukaryotic Elongation Factor 1 A2 Binding Protein". Degree, Universidade do Porto Faculdade de Ciências, 2005.

Intellectual property

Provisional application for patent
  1. 2021. "CD44 Glycoepitopes and chimeric vaccine glycoconjugates for cancer therapy and synthesis methods thereof".
    Protected
  2. 2021. "METHOD FOR CANCER DETECTION, PROGNOSIS, AND THERAPEUTIC SELECTION BASED ON SHORT CD44 GLYCOPROTEOFORMS".
    Protected

Other

Other output
  1. Glycoproteogenomics characterizes the CD44 splicing code driving bladder cancer invasion. 2021. Gaiteiro, C; Soares, J; Relvas-Santos, M; Peixoto, A; Ferreira, D; Brandão, A; Fernandes, E; et al.
    10.1101/2021.09.04.458979
Spin-off company
  1. 2019. GlycoMatters Biotech, Lda. Research and Develpment.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/11 Transferrin at the crossroads: asymmetrical iron lobe distribution in Hemocromatosis XXVII Encontro Luso-Galego de Química
Sociedade Portuguesa de Química (Porto, Portugal)
2023/07 The whereabouts of iron in the human body: insights from blood serum chemistry XXVIII Encontro Nacional da SPQ
Sociedade Portuguesa de Química (Aveiro, Portugal)
2021/11/11 Apotransferin in combination with induction chemotherapy protects against Escherichia coli infection in an acute myeloid leukemia mouse model Reunião Anual Sociedade Portuguesa de Hematologia (SPH) 2021
Sociedade Portuguesa de Hematologia
2019/09/03 Glycomics and Glycoproteomics: Unravelling the bladder cancer glycocode towards precision oncology. GLUPOR13 13th International Meeting of the Portuguese Carbohydrate Group.
Sociedade Portuguesa de Química; I3S (Porto, Portugal)
2019/09/03 Exploring the influence of oxygen and glucose on the bladder cancer glycome by cellular O-glycome reporter amplification: insights for targeted therapeutics. GLUPOR13 13th International Meeting of the Portuguese Carbohydrate Group.
I3S (Porto, Portugal)
2019/09/03 Glycoproteogenomics for addressing CD44 isoforms in bladder cancer. GLUPOR13 13th International Meeting of the Portuguese Carbohydrate Group.
I3S (Porto, Portugal)
2019/06/07 A Relação Agridoce Entre Açucares e Proteínas/The sweet and sour side of protein life "Um dia com..."
CEBAL - Centro de Biotecnologia Agrícola e Agro-Alimentar do Alentejo (Beja, Portugal)
2019/05/07 New insights into the molecular mechanisms underlying the pro-atherosclerotic effect of non-transferrin-bound iron 8th Congress of the International BioIron Society
EMBL, BioIron Society (Heidelberg, Germany)
2019/03/27 Exploring the influence of oxygen and glucose on the bladder cancer glycome by cellular O-glycome reporter amplification: insights for targeted therapeutics. Mass spectrometry and Carbohydrates 8th Workshop.
Universidade de Aveiro (Aveiro, Portugal)
2019/03/27 Glycomics and glycoproteomics: unravelling the cancer glycocode towards precision oncology. Mass spectrometry and Carbohydrates 8th Workshop.
Universidade de Aveiro (Aveiro, Portugal)
2019/02/06 Identification of protein post-translational modifications 5th Practical Course on LC-MS: From the basics to LC-MS data acquisition and interpretation
University of Aveiro Centro de Espectrometria de Massa (Aveiro, Portugal)
2018/10/09 The sweet and sour life of proteins: a tale of (glyco)proteomics at UPorto. Thermo Scientific Multi-Omics Seminar
ITQB – NOVA IBET Institute (Oeiras, Portugal)
2017/02/22 When less is more: applications of nanoLC-MS Universidade de Aveiro Centro de Espectrometria de Massa
From the basics to LC-MS data acquisition and interpretation (Aveiro, Portugal)
2017/02 Compreensão do papel da glicação não enzimática das proteínas do soro humano na acumulação e toxicidade do ferro na Diabetes Mellitus tipo 1./Understanding the role of non-enzymatic glycation of blood serum protein in iron toxicity and accumulation in type 1 diabetes mellitus. Reunião do Grupo Clínico do Serviço de Endocrinologia do Centro Hospitalar de São João
Serviço de Endocrinologia do Centro Hospitalar de São João (Porto, Portugal)
2015/07 Analysis of post-translational modifications by mass spectrometry. Analytical methods to study oxidative damage, antioxidants and drugs Meeting
Medical University of Bialystok - Faculty of Pharmacy (Bialystok, Poland)
2015/06/18 Proteomic Applications using the Orbitrap Encontro de Espectrometria de Massa", organized by Thermo Unicam
Thermo Unicam, (Porto, Portugal)
2015/05 Monitoring serum transferrin glycation by mass spectrometry Workshop "Mass spectrometry and Carbohydrates"
Universidade de Aveiro (Aveiro, Portugal)
2015/04 Trying to understand the site specificity of protein glycation: the case of serum transferrin. “Have a Cofee with the Orbitrap” organized by Thermo Unicam
Thermo Unicam, Universidade de Lisboa Faculdade de Ciências (Lisbon, Portugal)
2013/06 Mass Spectrometry - Resources and Experimental Oportunities
CEMUP - Centro de Materiais da Universidade do Porto (Porto, Portugal)
2009/12 Human serum albumin, a determinant ligand for NTBI speciation. First International Conference on Metal Chelation in Biology and Medicine
University of Bath (Bath, United Kingdom)
2009/06 Relevance of non-enzymatic post-translation modifications of human serum albumin for non-transferrin-bound iron speciation. International BioIron Society Meeting
International BioIron Society (Porto, Portugal)
2008/10 Towards an Understanding of the Chemical Nature of Non-Transferrin-Bound Iron Meeting of the London Biological Mass Spectrometry Discussion Group
University College London (London, United Kingdom)
2008/07 Towards an Understanding of the Chemical Nature of Non-Transferrin-Bound Iron. Post-Graduate Students Symposium
King's College London (London, United Kingdom)
2007/11 Studies on iron-citrate-albumin aqueous solutions: implications for NTBI speciation. London Iron Metabolism Research Group Scientific Meetings
London Iron Metabolism Research Group (London, United Kingdom)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2020/01/01 - Current Construction of a multivalent glycan-based nanovaccine for bladder cancer: A step towards effective immunotherapies .
Co-supervisor of Marta Filipa Relvas dos Santos
 PhD in Biomedical Sciencies (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/10/01 - 2023/12/14 "Avaliação do papel da especificidade da ligação do ferro à transferrina na Hemocromatose Hereditária"
Supervisor of Eduardo Ramos
 Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2022/04/15 - 2022/09 Péptidos derivados de hidrolisado de camarão como agentes neutracêuticos em PetFood
Supervisor
 Biotecnologia Medicinal (Degree)
Instituto Politecnico do Porto Escola Superior de Tecnologia da Saúde do Porto, Portugal
2020/09/15 - 2021/09/15 New Insights Into The Role of Extracelular Matrix on Human Decidualization
Co-supervisor
 BSc in Biology (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2021/02/08 - 2021/07/15 Estudo Proteómico de Biomarcadores na Hemocromatose Hereditária/Proteomics Study of Hereditary Haemochromatosis Biomarkers
Supervisor
 BSc in Biochemistry (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2019/09/30 - 2020/09 Cellular senescence and ovarian ageing.
Co-supervisor of David José Silva Abreu
 Licenciatura em Biologia (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2020/01/31 - 2020/07/31 Estudo da oxidação proteica em diferentes modelos de senescência celular prematura induzida por stress/Study of protein oxidation in different stress induced premature senescence cell models.
Supervisor of Paulo Jorge Cardoso Pinheiro
 Licenciatura em Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2020/01/31 - 2020/07 Especiação de Espécies de Ferro Tóxicas no Soro de Indivíduos com Sobrecarga deste Elemento/Non-transferrin-bound iron speciation in the blood serum of iron overload patients.
Supervisor of Rui Fernando Alves Mendes
 Licenciatura em Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2020/01/31 - 2020/07 Influence of Extracellular Matrix on Human Uterine Function: a Preliminary Approach
Co-supervisor of Teodora Garcia Lema Figueiredo
 Licenciatura em Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2018/09/01 - 2019/09/04 Estudo da etiologia do ferro não ligado à transferrina em indivíduos com diabetes mellitus tipo 1.
Supervisor of José Moutinho Guedes
 Licenciatura em Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2019/02/01 - 2019/07/31 Desenvolvimento de biocatalizadores para dessulfurização oxidativa.
Supervisor of Maria Clara Amador Macedo Dias
 Programa de Estágios Extra Curriculares (PEEC) (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2017/09/01 - 2018/12/13 Bladder cancer glycome and glycoproteome microenvironmental regulation: the role of oxygen and glucose.
Co-supervisor of Marta Filipa Relvas dos Santos
 Mestrado em Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2017/09/01 - 2018/12/12 Estudo da etiologia do ferro não ligado à transferrina em indivíduos com diabetes mellitus.
Supervisor of Cláudia Sofia Gomes Cardoso
 Licenciatura em Bioquímica (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2018/02/01 - 2018/07/31 Desenvolvimento de um método cromatográfico para a separação de complexos organometálicos.
Supervisor of Sara Luciana da Silva Cascais
 Programa de Estágios Extra Curriculares (PEEC) (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2016/02/01 - 2016/07/31 Estudos de coordenação de catecolatos ao Fe(III) com recurso à espectrometria de massa
Supervisor of Rita Prata Barbedo Magalhães
 PEEC - Pregrama de estágios extracurriculares (Other)
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
2016/02/01 - 2016/07/31 Desenvolvimento de um método analítico para a determinação de Fe(III)
Co-supervisor of Maria Inês Guedes Mano de Oliveira
 PEEC - Programa de Estágios Extra-curriculares (Other)
REQUIMTE LAQV Porto, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
2015/09/01 - 2016/07/08 Variação dos parâmetros hematopoiéticos e de toxicidade do ferro como biomarcadores de previsão da severidade clínica da Hemocromatose Hereditária ligada ao HFE.
Co-supervisor of André Sotero Araújo Ferreira
 Mestrado Integrado em Medicina (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014/09/01 - 2015/12/18 Glycoproteomic Characterization of Bladder Cancer Chemoresistant Cells
Co-supervisor of Diogo André Teixeira Neves
 Mestrado em Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2015/02/01 - 2015/07/31 Estudo da influência da glucose na ligação do ferro a proteínas do plasma do soro.
Supervisor of Maria Miguel Ferreira Pinto Menezes de Castro
 Programa de Estágios Extra Curriculares (PEEC) (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2015/02/01 - 2015/07/31 Estudo da influência da glucose na ligação do ferro a proteínas do plasma do soro.
Supervisor of Ângela Daniela Abreu Oliveira
 Programa de Estágios Extra Curriculares (PEEC) (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2011/09/01 - 2012/12/11 Caracterização dos produtos de glicação da transferrina do soro humano por espectrometria de massa.
Supervisor of Paulo Roberto Horta Sousa
 Mestrado em Bioquímica (Master)
Universidade de Aveiro, Portugal
2011/09/01 - 2012/12/11 Avaliação da influência da oxidação de péptidos e proteínas na quantificação de proteínas por espectrometria de massa.
Supervisor of Duarte Domingos Gouveia
 Mestrado em Bioquímica (Master)
Universidade de Aveiro, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2018/07/05 - 2018/07/06 12th IBCC - Inorganic and Bioinorganic Chemistry Conference da Sociedade Portuguesa de Química, Julho 2018, Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto Member of Organizing Committee (2018/07/05 - 2018/07/06)
Congress (Member of the Organising Committee)
 Sociedade Portuguesa de Química, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 - 2018 Regular participation in the organization of LAQV-REQUIMTE stand at "Mostra da Universidade do Porto" (2014 - 2018)
Exhibition (Other)
 REQUIMTE LAQV Porto, Portugal

Universidade do Porto, Portugal
2016/09/12 - 2016/09/14 3ª European Conference on Smart Inorganic Polymers (3rd EuSIPs Meeting), Setembro de 2016, Faculdade de Ciências da Universidade do Porto Member of Organizing Committee (2016/09/12 - 2016/09/14)
Meeting (Member of the Organising Committee)
 Rede de Química e Tecnologia Laboratório Associado para a Química Verde, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2016/09/08 - 2016/09/12 3ª EuSIPS training school (2016/09/08 - 2016/09/12)
Workshop (Member of the Organising Committee)
 REQUIMTE LAQV Porto, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2015/02 - 2015/02 Organizador e orientador de módulo experimental nas 2as Jornadas de Bioquímica da FCUP. Título do projeto executado “Determinação da oxidação proteica em fibroblastos humanos em senescência replicativa.” Fevereiro de 2015, Faculdade de Ciências da Universidade do Porto. (2015/02 - 2015/02)
Symposium (Other)
 Universidade do Porto Faculdade de Ciências, Portugal
2014/04 - 2014/04 Organizador e orientador de módulo experimental no II AEICBAS Biomedical Congress. Título do projeto executado “Determinação da oxidação proteica em fibroblastos humanos em senescência replicativa.”, Abril de 2014, Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto. (2014/04 - 2014/04)
Symposium (Other)
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012/06 - 2012/06 Proteomics Workshop 2012 Member of organizing committee (2012/06 - 2012/06)
Workshop (Member of the Organising Committee)
 Universidade de Aveiro Centro de Espectrometria de Massa, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2021/11/26 New roles for serum iron proteins during infection.
(Thesis) Main arguer
 Inês Isabel Simões Alves (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/11/11 Novos corantes alimentares: do estudo da interação de metais com antocianinas à descoberta de novas molóculas naturais
(Thesis) Main arguer
 Sara Ferreira Alves (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2019/09/05 Purinergic Calcium Signals in Tumour derived Endothelium
(Thesis) Main arguer
 Joana Rita de Almeida Vieira (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2019/07/08 Polifenóis em Arte – Investigação de Tintas Ferrogálhicas Medievais
(Thesis) Main arguer
 Filipa Alexandra Silva Campos (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2019/07/07 Fused in Sarcoma (FUS) gene regulation disruption in Spinocerebellar Ataxia Type 7 (SCA7)
(Thesis) Main arguer
 Ricardo Gel Santos Mota (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2017/12/22 CD44-glycoprofilling: Establishing the molecular basis for targeted therapeutics in bladder cancer.
(Thesis) Main arguer
 Eliana Janine de Paiva Soares (Master)
Universidade de Aveiro Departamento de Química, Portugal
2017/07/06 Diagnostic and risk assessment technics for tuberculosis
(Thesis) Main arguer
 Nuno André Ramos Rufino de Sousa (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2015/05/05 Study of the interaction between food polyphenolics and celiac disease related peptides.
(Thesis) Main arguer
 Ricardo Jorge Correia Dias (Master)
Universidade do Porto Faculdade de Ciências, Portugal

Consulting

Activity description Institution / Organization
2021/09/10 - Current I have been invited to be a consultor to the american company MassMatrix (www.massmatrix.bio). MassMatrix provides a cloud based multiomics data analysis platform. I have been collaborating as an advanced user, testing and advising in the development of new product functionalities. MassMatrix Inc., United States

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2023/02 - Current Termodinâmica Bioengenharia (Licenciatura) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/10 - Current Biological Chemistry Mestrado Integrado em Medicina Veterinária (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/01/11 - Current "Mass Spectrometry", Invited Lecture. Course: Análise Estrutural e Funcional em Bioengenharia/Structural and Functional Analysis in Bioengeneering Licenciatura em Bioengenharia (Licenciatura) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/10/15 - Current Invited Lecture in the Course "Iron Biology" Mestrado Integrado em Medicina (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/02 - Current Bioinorganic Chemistry Bioquímica (Licenciatura) Universidade do Porto Faculdade de Ciências, Portugal
2022/10/07 - 2022/10/07 Invited Lecture: "Fe Metalloprotein", Course: Iron Biology: metabolism and its regulation, Part of Integrated Master in Medicine Mestrado Integrado em Medicina (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/10/12 - 2021/10/12 Invited Lecture in the Course "Iron Biology" Title: Transferrin. Mestrado Integrado em Medicina (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/12/19 - 2020/12/19 "Mass Spectrometry", Invited Lecture. Course: Análise Estrutural e Funcional em Bioengenharia/Structural and Functional Analysis in Bioengeneering. 3rd year Master in Bioengeneering – Molecular Biotechnology, Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto Mestrado em Bioengenharia (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2018/05 - 2018/05 "NTBI Speciation". Invited Lecture, Iron Biology Course, GABBA - Graduate Program in Areas of Basic and Applied Biology - PhD Program, May 2018, I3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto GABBA - Graduate Program in Areas of Basic and Applied Biology - PhD Program (Doutoramento) Universidade do Porto, Portugal
2017/11 - 2017/11 "Mass Spectrometry", Invited Lecture. Course: Análise Estrutural e Funcional em Bioengenharia/Structural and Functional Analysis in Bioengeneering. 3rd year Master in Bioengeneering – Molecular Biotechnology, November 2017, Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto Mestrado em Bioengenharia (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2017/05 - 2017/05 "NTBI Speciation". Invited Lecture, Iron Biology Course, GABBA - Graduate Program in Areas of Basic and Applied Biology - PhD Program, May 2017, I3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto GABBA - Graduate Program in Areas of Basic and Applied Biology - PhD Program (Doutoramento) Universidade do Porto, Portugal
2016/12 - 2016/12 "Mass Spectrometry", Invited Lecture. Course: Análise Estrutural e Funcional em Bioengenharia/Structural and Functional Analysis in Bioengeneering. 3rd year Master in Bioengeneering – Molecular Biotechnology, December 2016, Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto Mestrado em BioEngenharia (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2016/05 - 2016/05 "NTBI Speciation". Invited Lecture, Iron Biology Course, GABBA - Graduate Program in Areas of Basic and Applied Biology - PhD Program, May 2016, I3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto GABBA - Graduate Program in Areas of Basic and Applied Biology - PhD Program (Doutoramento) Universidade do Porto, Portugal
2016/05 - 2016/05 Proteómica: das Modificações Pós-tradução à Biologia Estrutural/Proteomics from post-translational modifications to structural biology, Invited Lecture. Course: Química Bioanalítica, 1st year MSc in Biochemistry, May 2016, Faculdade de Ciências da Universidade do Porto Mestrado em Bioquímica (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2015/10 - 2015/10 "Mass Spectrometry", Invited Lecture. Course: Análise Estrutural e Funcional em Bioengenharia/Structural and Functional Analysis in Bioengeneering. 3rd year Master in Bioengeneering – Molecular Biotechnology, October 2015, Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto Mestrado em BioEngenharia (Mestrado integrado) Universidade do Porto Faculdade de Engenharia, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/05 - 2015/05 "NTBI Speciation". Invited Lecture, Iron Biology Course, GABBA - Graduate Program in Areas of Basic and Applied Biology - PhD Program, May 2015, I3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto GABBA - Graduate Program in Areas of Basic and Applied Biology - PhD Program (Doutoramento) Universidade do Porto, Portugal
2014/10 - 2014/10 "Mass Spectrometry", Invited Lecture. Course: Análise Estrutural e Funcional em Bioengenharia/Structural and Functional Analysis in Bioengeneering. 3rd year Master in Bioengeneering – Molecular Biotechnology, October 2014, Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto Mestrado em BioEngenharia (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2014/05 - 2014/05 "NTBI Speciation". Invited Lecture, Iron Biology Course, GABBA - Graduate Program in Areas of Basic and Applied Biology - PhD Program, May 2014, I3S – Instituto de Investigação e Inovação em Saúde, Universidade do Porto GABBA - Graduate Program in Areas of Basic and Applied Biology - PhD Program (Doutoramento) Universidade do Porto, Portugal
2013/10 - 2013/10 "Mass Spectrometry", Invited Lecture. Course: Métodos Avançados de Análise Estrutural/Advanced Methods in Structural Analysis, 1st year MSc in Chemistry, October 2013, Faculdade de Ciências da Universidade do Porto. Mestrado em Química (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
2012/02/28 - 2012/02/28 Metabolismo do Ferro e Patologias Associadas/Iron Metabolism and Associated Pathologies, Course: Desenvolvimento Clínico do Medicamento/Clinical Development of Medicins, 2nd year, BSc in Biomedicine, Escola Superior de Saúde, Universidade de Aveiro. Licenciatura em Biomedicina (Licenciatura) Universidade de Aveiro Escola Superior de Saúde de Aveiro, Portugal
2007 - 2007 Biochemistry and Biotechnology Master in Pharmacy (Master) King's College London Department of Pharmacy, United Kingdom
2006 - 2006 Introduction to Chemistry Fundation Course in Natural Sciences (Bachelor) King's College London Department of Pharmacy, United Kingdom

Evaluation committee

Activity description
Role 		Institution / Organization Funding entity
2020/06/22 - Current External Evaluator, Action H2020 FET-Open 2018-2020, Challenging Current Thinking, Research and Innovation Action (RIA), 24th January 2020 deadline (Invited external evaluator)
Evaluator
 Research Executive Agency, Belgium European Commission

Research Executive Agency
2019 - Current External Evaluator, Action H2020 FET-Open 2018-2020, Challenging Current Thinking, Research and Innovation Action (RIA), 18th Septembre 2019 deadline (Invited external evaluator - excluded due to conflict of interest) Research Executive Agency, Belgium Research Executive Agency

European Commission
2021/06/14 - 2021/07/07 External Evaluator, Action H2020 Pathfinder Open 2021 (Invited external evaluator)
Evaluator
 Research Executive Agency, Belgium Research Executive Agency
2019/03/01 - 2019/03/31 External Evaluator, Action H2020 FET-Open 2018-2020, Challenging Current Thinking, Research and Innovation Action (RIA), 24th January 2019 call
Evaluator
 Research Executive Agency, Belgium Research Executive Agency

European Commission

Journal scientific committee

Journal title (ISSN) Publisher
2020/06 - Current Phytomedicine Plus (2667-0313) Elsevier
2020 - Current Scientific Reports (2045-2322) Springer Science and Business Media LLC
2020 - Current Expert Review of Clinical Pharmacology (1751-2441) Informa UK (Taylor & Francis)
2020 - Current Biomolecules (2218-273X) MDPI AG
2019 - Current Bioscience Reports (1573-4935) Portland Press
2019 - Current European Biophysics Journal (1432-1017) Springer-Verlag
2019 - Current Cells (2073-4409) MDPI AG
2019 - Current Nutrients (2072-6643) MDPI AG
2018 - Current Molecules (1420-3049) MDPI AG
2017 - Current European Journal of Pharmaceutical Sciences (0928-0987) Elsevier

Other jury / evaluation

Activity description Institution / Organization
2019/11/13 - Current Evaluation Jury of the probation year for the PhD programme in Biomedical Sciences. Student: Eliane Janine de Paiva Soares. Title: A library of colorectal cancer immunogenic glycopeptides: A step towards novel theragnostics. Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/02/21 - Current Selection Committee (vogal) for a Research Fellowship in the project “Novos FERtilizantes para prevenir a clorose” (PTDC/AGRPRO/3515/2014) REQUIMTE LAQV Porto, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal
2016/09 - Current Selection Committee (Vogal) for a posdoctoral position HEALTH_RL3_PHD_QUIBI_01,in the project NORTE-01-0145-FEDER-000024 na instituição ICETA. REQUIMTE LAQV Porto, Portugal

Universidade do Porto Instituto de Ciências e Tecnologias Agrárias e Agro-Alimentares, Portugal