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Catarina Sofia Rodrigues do Carmo. Concluiu o(a) Mestrado em Molecular Genetics em 2015 pelo(a) Universidade do Minho Escola de Ciências e Licenciatura em Health Sciences em 2013 pelo(a) Universidade de Lisboa. Atua na(s) área(s) de Ciências Naturais com ênfase em Ciências Biológicas com ênfase em Biologia.
Identification

Personal identification

Full name
Catarina Sofia Rodrigues do Carmo

Citation names

  • Carmo, Catarina

Author identifiers

Ciência ID
7B13-6D80-3999

Knowledge fields

  • Natural sciences - Biological Sciences - Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Advanced (C1) Proficiency (C2) Proficiency (C2) Proficiency (C2) Proficiency (C2)
Education
Degree Classification
2017/01/01 - 2021/12/01
Ongoing
 Integrative Biology and Biomedicine (Doutoramento)
Major in Biology
Instituto Gulbenkian de Ciência, Portugal
"Understanding the role of histone tails for chromosome condensation" (THESIS/DISSERTATION)
2015
Concluded
 Molecular Genetics (Mestrado)
Universidade do Minho Escola de Ciências, Portugal
"Role of sirtuin 3 on mitochondrial dynamics in Huntington's disease striatal cells" (THESIS/DISSERTATION)
 19/20 (120 ECTS) (Best of the class)
2013
Concluded
 Health Sciences (Licenciatura)
Universidade de Lisboa, Portugal
"n/a" (THESIS/DISSERTATION)
 16/20 (180 ECTS) (Second best of the class)
Affiliation

Science

Category
Host institution 		Employer
2017/01 - 2021/12 Research Trainee (Research) Instituto Gulbenkian de Ciência, Portugal
Instituto Gulbenkian de Ciência, Portugal
2015/12 - 2016/12 Research Assistant (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014 - 2015 Research Trainee (Research) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Projects

Grant

Designation Funders
2017 - 2020 ChromoCellDev - Chromosome Architecture and the Fidelity of Mitosis during Development
ERC-2014-STG638917-ChromoCellDev
PhD Student Fellow
Instituto Gulbenkian de Ciência, Portugal
 European Research Council
Ongoing
2014 - 2015 Role of sirtuin 3 on mitochondrial function and dynamics in Huntington’s disease striatal cells
EXPL/BIM-MEC/2220/2013
Master Student Fellow
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Carmo, Catarina; Araújo, Margarida; Oliveira, Raquel A.. "Microinjection Techniques in Fly Embryos to Study the Function and Dynamics of SMC Complexes". In Methods in Molecular Biology, edited by Badrinarayanan A, 251-268. Oeiras, Portugal: Springer New York, 2019.
    Published • 10.1007/978-1-4939-9520-2_19
  2. Ferreira, I. Luísa; Carmo, Catarina; Naia, Luana; I. Mota, Sandra; Cristina Rego, A.. "Assessing Mitochondrial Function in In Vitro and Ex Vivo Models of Huntington’s Disease". In Methods in Molecular Biology, edited by Dunnet SB; Precious S; Rosser A, 415-442. Coimbra, Portugal: Springer New York, 2018.
    Published • 10.1007/978-1-4939-7825-0_19
  3. Carmo, Catarina; Naia, Luana; Lopes, Carla; Rego, A. Cristina. "Mitochondrial Dysfunction in Huntington’s Disease". In Advances in Experimental Medicine and Biology, edited by Pereira de Almeida L.; Nóbrega C, 59-83. Coimbra, Portugal: Springer International Publishing, 2018.
    Published • 10.1007/978-3-319-71779-1_3
Conference poster
  1. Carmo, Catarina; João Coelho; Ana Boavida; Raquel A Oliveira. "Lodestar, a protein with a dual role in mitotic transcription inactivation and sister chromatid resolution". Paper presented in CellBio Virtual 2020 - American Society of Cell Biology, 2020.
  2. Carmo, Catarina; Oliveira, Raquel A. "Dissecting the structural role of histone tails on mitotic chromosome assembly". Paper presented in Inaugural Trieste Cell Cycle Meeting, 2019.
  3. Carmo, Catarina; Oliveira, Raquel A. "Understanding the dynamics between condensin I and topoisomerase II on metaphase chromosomes". Paper presented in EMBO|EMBL symposium in Principles of Chromosome Structure and Function, 2018.
  4. Carmo, Catarina; Brás, Ines; Oliveira, Raquel A. "Deciphering the minimal histone landscape required for mitotic chromosome architecture". Paper presented in Portuguese Drosophila meeting, 2017.
  5. Naia, Luana; Cunha-Oliveira, Teresa; Rosenstock, Tatiana R.; Oliveira Ana M; Ribeiro, Márcio; Carmo, Catarina; Oliveira-Sousa, Sofia I.; et al. "Activation of pyruvate dehydrogenase complex by sodium butyrate ameliorates mitochondrial and motor phenotype in Huntington’s disease models.". Paper presented in MitoPorto International Symposium, 2017.
  6. Naia, Luana; Carmo, Catarina; Oliveira, Ana M; Valero, Jorge; Lopes, Carla; Hayden, Michael R.; Oliveira, C. R.; Rosenstock, Tatiana R.; Rego, Ana Cristina. "Exacerbated SIRT3 activity alters mitochondrial function and dynamics in Huntington’s disease models.". Paper presented in Society for Neuroscience 46th Annual Meeting, 2016.
  7. Carmo, Catarina; Naia, Luana; Oliveira, Ana M; Valero, Jorge; Rosenstock, Tatiana R.; Rego, Ana Cristina. "Sirtuin 3 overexpression affects mitochondrial dynamics in striatal cells derived from Huntington’s disease knock-in mice". Paper presented in XIV Meeting of the Portuguese Society for Neurosciences, 2015.
  8. Naia, Luana; Oliveira, Ana M; Carmo, Catarina; Oliveira, C. R.; Rosenstock, Tatiana R.; Rego, Ana Cristina. "Exacerbated mitochondrial dysfunction and oxidative stress following SIRT3 overexpression in Huntington’s disease mice striatal cells.". Paper presented in XIV Meeting of the Portuguese Society for Neurosciences, 2015.
  9. Carmo, Catarina; Naia, Luana; Oliveira, Ana M.; Valero, Jorge; Rosenstock, Tatiana R.; Rego, Ana Cristina. "Altered mitochondrial function and dynamics imposed by sirtuin 3 overexpression in Huntington’s disease striatal cells". Paper presented in XXXIX Portuguese Genetics Conference, 2015.
Journal article
  1. Naia, Luana; Carmo, Catarina; Campesan, S; Cotton VE; Valero, Jorge; Lopes, C; Fão, Ligia; et al. "Mitochondrial SIRT3 confers neuroprotection in Huntington’s disease by regulation of oxidative challenges and mitochondrial dynamics". (2020):
    Submitted
  2. Naia, Luana; Cunha-Oliveira, Teresa; Rodrigues, Joana; Rosenstock, Tatiana R.; Oliveira, Ana; Ribeiro, Márcio; Carmo, Catarina; et al. "Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease". The Journal of Neuroscience 37 10 (2017): 2776-2794. http://dx.doi.org/10.1523/jneurosci.2006-14.2016.
    10.1523/jneurosci.2006-14.2016
  3. Naia, Luana; Rosenstock, Tatiana R.; Oliveira, Ana M.; Oliveira-Sousa, Sofia I.; Caldeira, Gladys L.; Carmo, Catarina; Laço, Mário N.; et al. "Comparative Mitochondrial-Based Protective Effects of Resveratrol and Nicotinamide in Huntington’s Disease Models". Molecular Neurobiology 54 7 (2016): 5385-5399. http://dx.doi.org/10.1007/s12035-016-0048-3.
    10.1007/s12035-016-0048-3
Thesis / Dissertation
  1. Carmo, Catarina. "Deciphering the role of histone tails in mitotic chromosome architecture". PhD, Universidade de Coimbra Centro de Neurociências e Biologia Celular, 2022.
  2. Carmo, Catarina. "Role of sirtuin 3 on mitochondrial dynamics in Huntington’s disease striatal cells". Master, Universidade de Coimbra Centro de Neurociências e Biologia Celular, 2015.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2018 Re-establishment of mitochondrial network, transport and function by SIRT3 confers neuroprotection in Huntington's disease models. MitoPorto International Symposium: Mitochondrial evolution, metabolism & disease
(Porto, Portugal)
2016 Increased levels of SIRT3 alter mitochondrial dynamics in Huntington’s disease striatal cells XLV Meeting of the Portuguese Society for Pharmacology
(Porto, Portugal)
2015 Altered mitochondrial dynamics caused by sirtuin 3 overexpression in a cellular model of Huntington’s disease. X Young European Scientist Meeting
(Porto, Portugal)
2015 Overexpression of sirtuin 3 alters mitochondrial dynamics in a cellular model of Huntington’s disease XXIX Meeting of the Study Group on Brain Aging and Dementia.
(Aveiro, Portugal)

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2018 - 2018 Participation in the organizing committee of the 12th AMeeGuS (Annual Meeting of Gulbenkian Students), a scientific retreat for PhDs students from Instituto Gulbenkian de Ciência. (March 4th – 7th, Évora, Portugal) (2017 - 2018)
Meeting (Member of the Organising Committee)
 Instituto Gulbenkian de Ciência, Portugal

Mentoring / Tutoring

Topic Student name
2016 - 2016 Molecular and cellular mechanisms of neuronal dysfunction in neurodegenerative diseases Oluwwayemisi Oshodi
Distinctions

Award

2015 Professor Ernesto Morais Best Oral Presentation Award (in Neurosciences)
X Young European Scientist Meeting, Portugal