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Identification

Personal identification

Full name
Alexandra Maria Fonseca Castelo Dias de Carvalho

Citation names

  • Carvalho, A.

Author identifiers

Ciência ID
5B19-EAA3-A589
ORCID iD
0000-0002-0281-3422

Email addresses

  • alexandra.d.carvalho@ipleiria.pt (Professional)

Addresses

  • Escola Superior de Turismo e Tecnologia do Mar Campus 4 Rua do Conhecimento, nº 4, 2520–614 , Peniche, Leiria, Portugal (Professional)

Knowledge fields

  • Exact Sciences - Physical Sciences - Condensed Matter Physics
  • Engineering and Technology - Materials Engineering - Materials Engineering
  • Agrarian Sciences - Agrarian and Food Biotechnology - Diagnostics
Education
Degree Classification
2001
Concluded
 Física (Doutoramento)
Major in Física da Matéria Condensada
Instituto Superior Técnico Departamento de Física, Portugal
"Estudo por Ressonância Mgnética Nuclear da Ordem e Dinâmica Molecular em Mesofase Esméticas de Dupla Camada" (THESIS/DISSERTATION)
1994/03/08
Concluded
 Mestrado em Física (Mestrado)
Major in Fìsica da Matéria Condensada e Ciência dos Materiais
Universidade de Lisboa Faculdade de Ciências, Portugal
"Propriedades Magnéticas de Óxidos Metálicos Tipo Espinela" (THESIS/DISSERTATION)
1989/12/12
Concluded
 Física (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
Affiliation

Science

Category
Host institution 		Employer
2011/04/01 - 2015/05/31 Science and Technology Management Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal
1995/09/01 - 1999/08/01 Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal
1991/09/01 - 1993/08/01 Researcher (Research) Fundação para a Ciência e a Tecnologia, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2022/09/01 - Current Invited Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
Instituto Politécnico de Leiria Escola Superior de Turismo e Tecnologia do Mar de Peniche, Portugal
2000/03/01 - 2010/09/26 Adjunct Teacher (Polytechnic Teacher) Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa, Portugal
1999/09/01 - 2000/04/01 Invited Assistant (University Teacher) Universidade Lusófona de Humanidades e Tecnologias, Portugal
1994/09/01 - 1995/08/01 Adjunct Teacher (Polytechnic Teacher) Universidade Lusófona de Humanidades e Tecnologias, Portugal

Other Careers

Category
Host institution 		Employer
2020/09/06 - 2022/08/31 Professor do ensino básico e secundário (Professor do ensino básico e secundário) Escola Internacional de Torres Vedras, Portugal

Positions / Appointments

Category
Host institution 		Employer
2015/06/01 - 2019/05/31 Organic Unit Sub-director IEQUALTECS, Lda, Portugal

Others

Category
Host institution 		Employer
2020/09/06 - Current Gestor IEQUALTECS, Lda, Portugal
Projects

Contract

Designation Funders
2016/05/01 - 2018/04/30 Métodos de Ressonância Magnética para Previsão Precoce do Acastanhamento Interno de Pera Rocha e Amadurecimento de Produtos Hortofrutícolas, Projeto CENTRO-01-0247-FEDER-10959
CENTRO-01-0247-FEDER-10959
Principal investigator
IEQUALTECS, Lda, Portugal
Concluded
Outputs

Publications

Journal article
  1. Carvalho, A.. "Foundations and trends of high resolution energy dispersive PIXE (HiRED-PIXE)". Nuclear Inst. and Methods in Physics Research B 479 (2020): 187-193.
  2. Carvalho, A. . Corresponding author: Carvalho, A.. "Unilateral NMR, A New Approach to the Assessment of Rocha Pear Stored in Controlled Atmosphere during Long Periods". SF Journal of Biotechnology and Biomedical Engineering 2 1 (2019): 1009.
  3. Mendes, Goncalo; Faria, Monica; Carvalho, Alexandra; Clara Goncalves, M.; de Pinho, Maria Norberta. "Structure of water in hybrid cellulose acetate-silica ultrafiltration membranes and permeation properties". Carbohydrate Polymers 189 (2018): 342-351. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000428322000042&KeyUID=WOS:000428322000042.
    10.1016/j.carbpol.2018.02.030
  4. Carvalho, Alexandra; Goncalves, M. Clara; Corvo, M. Luisa; Martins, M. Barbara F.. "Development of New Contrast Agents for Imaging Function and Metabolism by Magnetic Resonance Imaging". Magnetic Resonance Insights 10 (2017): 1-4. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000406149600001&KeyUID=WOS:000406149600001.
    10.1177/1178623X17722134
  5. Marcelino, Paulo; Susana Marinho, H.; Campos, Maria Celeste; Neves, Ana Rita; Real, Carla; Fontes, Filipa S.; Carvalho, Alexandra; et al. "Therapeutic activity of superoxide dismutase-containing enzymosomes on rat liver ischaemia-reperfusion injury followed by magnetic resonance microscopy". European Journal of Pharmaceutical Sciences 109 (2017): 464-471. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000413325000048&KeyUID=WOS:000413325000048.
    10.1016/j.ejps.2017.09.008
  6. Soares, Paula I. P.; Laia, Cesar A. T.; Carvalho, Alexandra; Pereira, Laura C. J.; Coutinho, Joana T.; Ferreira, Isabel M. M.; Novo, Carlos M. M.; Borges, Joao Paulo. "Iron oxide nanoparticles stabilized with a bilayer of oleic acid for magnetic hyperthermia and MRI applications". Applied Surface Science 383 (2016): 240-247. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000378091700028&KeyUID=WOS:000378091700028.
    10.1016/j.apsusc.2016.04.181
  7. Fundo, Joana F.; Galvis-Sanchez, Andrea; Madureira, Ana Raquel; Carvalho, Alexandra; Feio, Gabriel; Silva, Cristina L. M.; Quintas, Mafalda A. C.. "NMR water transverse relaxation time approach to understand storage stability of fresh-cut 'Rocha' pear". Lwt-Food Science and Technology 74 (2016): 280-285. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000383524300038&KeyUID=WOS:000383524300038.
    10.1016/j.lwt.2016.07.050
  8. Taborda, A.; Desbree, A.; Carvalho, A.; Chaves, P. C.; Reis, M. A.. "Energetic electron processes fluorescence effects for structured nanoparticles X-ray analysis and nuclear medicine applications". Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions With Materials and Atoms 381 (2016): 122-131. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000380082700020&KeyUID=WOS:000380082700020.
    10.1016/j.nimb.2016.05.031
  9. Palma, Susana I. C. J.; Rodrigues, Carlos A. V.; Carvalho, Alexandra; del Puerto Morales, Maria; Freitas, Filomena; Fernandes, Alexandra R.; Cabral, Joaquim M. S.; Roque, Ana C. A.. "A value-added exopolysaccharide as a coating agent for MRI nanoprobes". Nanoscale 7 34 (2015): 14272-14283. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000360117200011&KeyUID=WOS:000360117200011.
    10.1039/c5nr01979f
  10. Carvalho, A.; Domingues, I.; Goncalves, M. Clara. "Core-shell superparamagnetic nanoparticles with interesting properties as contrast agents for MRI". Materials Chemistry and Physics 168 (2015): 42-49. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000367493000007&KeyUID=WOS:000367493000007.
    10.1016/j.matchemphys.2015.10.030
  11. Fundo, Joana F.; Carvalho, Alexandra; Feio, Gabriel; Silva, Cristina L. M.; Quintas, Mafalda A. C.. "Relationship between molecular mobility, microstructure and functional properties in chitosan/glycerol films". Innovative Food Science & Emerging Technologies 28 (2015): 81-85. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000351646700011&KeyUID=WOS:000351646700011.
    10.1016/j.ifset.2015.01.009
  12. Carvalho, A.; Sebastiao, P. J.; Fonseca, I.; Matos, J.; Clara Goncalves, M.. "Silica and silica organically modified nanoparticles: Water dynamics in complex systems". Microporous and Mesoporous Materials 217 (2015): 102-108. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000360596100014&KeyUID=WOS:000360596100014.
    10.1016/j.micromeso.2015.06.015
  13. Palma, Susana I. C. J.; Carvalho, Alexandra; Silva, Joana; Martins, Pedro; Marciello, Marzia; Fernandes, Alexandra R.; del Puerto Morales, Maria; Roque, Ana C. A.. "Covalent coupling of gum arabic onto superparamagnetic iron oxide nanoparticles for MRI cell labeling: physicochemical and in vitro characterization". Contrast Media & Molecular Imaging 10 4 (2015): 320-328. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000359420500005&KeyUID=WOS:000359420500005.
    10.1002/cmmi.1635
  14. Palma, Susana I. C. J.; Marciello, Marzia; Carvalho, Alexandra; Veintemillas-Verdaguer, Sabino; del Puerto Morales, Maria; Roque, Ana C. A.. "Effects of phase transfer ligands on monodisperse iron oxide magnetic nanoparticles". Journal of Colloid and Interface Science 437 (2015): 147-155. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000345109000020&KeyUID=WOS:000345109000020.
    10.1016/j.jcis.2014.09.019
  15. Cardoso, Bernardo de P.; Vicente, Ana I.; Ward, Joseph B. J.; Sebastiao, Pedro J.; Vaca Chavez, Fabian; Barroso, Sonia; Carvalho, Alexandra; et al. "Fe(III) salEen derived Schiff base complexes as potential contrast agents". Inorganica Chimica Acta 432 (2015): 258-266. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000355127300033&KeyUID=WOS:000355127300033.
    10.1016/j.ica.2015.04.026
  16. Fundo, Joana F.; Amaro, Ana L.; Madureira, Ana Raquel; Carvalho, Alexandra; Feio, Gabriel; Silva, Cristina L. M.; Quintas, Mafalda A. C.. "Fresh-cut melon quality during storage: An NMR study of water transverse relaxation time". Journal of Food Engineering 167 (2015): 71-76. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000362856300012&KeyUID=WOS:000362856300012.
    10.1016/j.jfoodeng.2015.03.028
  17. Fundo, J.F.; Fernandes, R.; Almeida, P.M.; Carvalho, A.; Feio, G.; Silva, C.L.M.; Quintas, M.A.C.. "Molecular mobility, composition and structure analysis in glycerol plasticised chitosan films". Food Chemistry 144 (2014): 2-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886420587&partnerID=MN8TOARS.
    10.1016/j.foodchem.2013.05.127
  18. Carvalho, A.; Martins, M. B. F.; Corvo, M. L.; Feio, G.. "Enhanced contrast efficiency in MRI by PEGylated magnetoliposomes loaded with PEGylated SPION: Effect of SPION coating and micro-environment". Materials Science & Engineering C-Materials For Biological Applications 43 (2014): 521-526. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000342529000065&KeyUID=WOS:000342529000065.
    10.1016/j.msec.2014.07.055
  19. Faria, M. R.; Cruz, M. M.; Goncalves, M. C.; Carvalho, A.; Feio, G.; Martins, M. B. F.. "Synthesis and characterization of magnetoliposomes for MRI contrast enhancement". International Journal of Pharmaceutics 446 1-2 (2013): 183-190.
    10.1016/j.ijpharm.2013.02.025
  20. Carvalho, A.; Goncalves, M. C.; Martins, M. B. F.; Meixedo, D.; Feio, G.. "Relaxivities of magnetoliposomes: The effect of cholesterol". Magnetic Resonance Imaging 31 4 (2013): 610-612.
    10.1016/j.mri.2012.10.024
  21. Martins, M.B.A.F.; Corvo, M.L.; Marcelino, P.; Marinho, H.S.; Feio, G.; Carvalho, A.. "New long circulating magnetoliposomes as contrast agents for detection of ischemia-reperfusion injuries by MRI". Nanomedicine: Nanotechnology, Biology, and Medicine (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84880581796&partnerID=MN8TOARS.
    10.1016/j.nano.2013.06.008
  22. Taborda, A.; Reis, M. A.; Chaves, P. C.; Carvalho, A.. "L X-Rays RYIED Oscillations and Proton-NMRD of Gd2O3 Nanoparticles". Physics Research International 2011 (2011):
    10.1155/2011/705686
  23. Reis, M. A.; Carvalho, A.; Taborda, A.; Quaresma, A.; Dias, G.; Alves, L. C.; Mota, M.; et al. "High airborne PM2.5 chlorine concentrations link to diabetes surge in Portugal". Science of the Total Environment 407 21 (2009): 5726-5734.
    10.1016/j.scitotenv.2009.07.029
  24. Taborda, A.; Carvalho, A.. "Superparamagnetic iron oxide nanoparticles - Proton Nuclear Magnetic Resonance Dispersion curves". European Physical Journal-Applied Physics 43 2 (2008): 145-148.
    10.1051/epjap:2008095
  25. Carvalho, A.; Taborda, A.. "Unusual longitudinal relaxation time behaviour of colloidal solutions of superparamagnetic nanoparticles". European Physical Journal-Applied Physics 40 3 (2007): 265-268.
    10.1051/epjap:2007156
  26. Carvalho, A; Sebastiao, PJ; Ribeiro, AC; Nguyen, HT; Vilfan, M. "Molecular dynamics in tilted bilayer smectic phases: A proton nuclear magnetic resonance relaxometry study". Journal of Chemical Physics 115 22 (2001): 10484-10492.
    10.1063/1.1413744
  27. Dong, RY; Carvalho, A; Sebastiao, PJ; Nguyen, HT. "Deuteron NMR study of molecular dynamics in a compound exhibiting a reentrant nematic phase". Physical Review E 62 3 (2000): 3679-3686.
    10.1103/PhysRevE.62.3679
  28. Carvalho, A; Sebastiao, PJ; Ferraz, A; Ribeiro, AC; Nguyen, HT. "Molecular order in bilayer, anticlinic and ferroelectric smectic C mesophases". European Physical Journal E 2 4 (2000): 351-358.
    10.1007/s101890050017
  29. Carvalho, A; Sebastiao, PJ; Nguyen, HT. "NMR study of the molecular order in a liquid crystal with peculiar smectic phases". Molecular Crystals and Liquid Crystals Science and Technology Section a-Molecular Crystals and Liquid Crystals 331 (1999): 1949-1956. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000082878400013&KeyUID=WOS:000082878400013.
  30. GODINHO, M; CARVALHO, A; NOGUES, M; DORMANN, JL; SEQQAT, M. "FIELD AND TEMPERATURE-DEPENDENCE OF MAGNETIC VISCOSITY IN RANDOMLY CANTED LI-TI FERRITE". Journal of Magnetism and Magnetic Materials 133 1-3 (1994): 457-459.
    10.1016/0304-8853(94)90594-0
  31. MENDONCA, MH; NUNES, MR; COSTA, FMA; CARVALHO, A; GODINHO, MM. "STUDIES OF THE SPINEL SOLID-SOLUTION CO2RU1-XFEXO4". Journal of Materials Chemistry 4 4 (1994): 515-517.
    10.1039/jm9940400515
  32. Freitas, M. C.; Lanca, M. C.; Carvalho, A. M.; Decorte, F.. "CODES TO COMPUTE RELEVANT GAMMA-GAMMA AND GAMMA-X TRUE-COINCIDENCE LINES IN ABSOLUTE COUNTING OF GAMMA-RAYS WITH A LEPD". Biological Trace Element Research 26-7 (1990): 33-41.
    10.1007/bf02992656
  33. Freitas, M.C.; Lanca, M.C.; Carvalho, A.M.; De Corte, F.. "CADEIA and REJECT: Codes to compute relevant ¿-¿ and ¿-X true-coincidence lines in absolute counting of gamma rays with a LEPD". Biological Trace Element Research 26-27 (1990): 33-41. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025610475&partnerID=MN8TOARS.
  34. FREITAS, MC; LANCA, MC; CARVALHO, AM; DECORTE, F. "CODES TO COMPUTE RELEVANT GAMMA-GAMMA AND GAMMA-X TRUE-COINCIDENCE LINES IN ABSOLUTE COUNTING OF GAMMA-RAYS WITH A LEPD". Biological Trace Element Research 26-7 (1990): 33-41. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:A1990EM70100006&KeyUID=WOS:A1990EM70100006.
    10.1007/BF02992656

Intellectual property

Patent
  1. Carvalho, A.. 2020. "DEMAFRUNI - Método para determinação do estado de maturação de fruta climatérica por ressonância magnética unilateral não invasiva". Portugal.
  2. Carvalho, A.. 2015. "Multifunctional Superparamagnetic Nanosystem as Contrast Agent for Magnetic Resonance Imaging and its Production Method". Portugal.
Activities

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2019 NMR em fruta climatérica
(Thesis) Arguer
 Maria Leonor Santos Pintado da Silva Castel-Branco (Master)
2015 Bioengenharia : nanopartículas com aplicações biomédicas
Thesis Member
 Susana Isabel Conde Jesus Palma (PhD)
2014 Biotecnologia: aplicação de RMN ao estudo de frutas climatéricas.
Thesis Member
 Joana de Freitas Salgado do Fundo (PhD)
Universidade Católica Portuguesa Portuguesa Centro de Biotecnologia e Química Fina, Portugal
2012 Bioengenharia e Nanossistemas: nanopartículas com aplicações biomédicas
Supervisor
 Telma Pereira da Silva (Master)
2006 Engenharia Fi´sica, Especialidade de Fi´sica Nuclear Aplicada: relaxometria de sistemas particulados
Supervisor
 Ana Canaveira Taborda (Master)
Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal
Distinctions

Award

2014 Melhor Poster
Elsevier Ltd, United Kingdom
2012 Melhor Poster
Universidade Nova de Lisboa Centro de Investigação em Materiais, Portugal