Personal identification

Full name

Carlos Lopes

Citation names

• Lopes, Carlos

Author identifiers

Ciência ID

5B12-908A-21A2

ORCID iD

0000-0002-6136-0478

Telephones

Mobile phone

• 917497526 (Personal)

	Degree	Classification
2009/12/17 Concluded	Engenharia Biológica (Mestrado integrado) Universidade do Algarve, Portugal "Produção, Purificação e Estabilidade Proteolítica da proteína Priónica" (THESIS/DISSERTATION)	13
2008/06/06 Concluded	Ciências de Engenharia Biológica (Licenciatura) Universidade do Algarve, Portugal	11

Science

	Category Host institution	Employer
2016/02/01 - 2019/05/31	Research Assistant (Research)	Centro de Ciências do Mar, Portugal
	Centro de Ciências do Mar, Portugal

Grant

	Designation	Funders
2015/08/01 - 2016/01/31	BTI-Incentivo/EQB/LA0023/2014 BTI-Incentivo/EQB/LA0023/2014 Research Technician Fellow Universidade do Algarve Centro de Investigação em Biomedicina, Portugal
2015/08 - 2016/01	BTI-Incentivo/EQB/LA0023/2014 BTI-Incentivo/EQB/LA0023/2014	N/A

Contract

	Designation	Funders
2016/02/01 - 2019/05/31	European Marine Biology Resource Infrastructure Cluster 654008 Other Centro de Ciências do Mar, Portugal	European Commission Seventh Framework Programme for Research and Technological Development Socio Economic Sciences and Humanities Concluded
2012/05/01 - 2015/04/30	A Biophysical Approach to Oxidative Protein Folding in the ER: Relative Importance of Ero1 and Prdx4 alternative pathways PTDC/QUI-BIQ/119677/2010 Research Fellow Universidade do Algarve, Portugal	Fundação para a Ciência e a Tecnologia
2012/05 - 2015/04	A Biophysical Approach to Oxidative Protein Folding in the ER: Relative Importance of Ero1 and Prdx4 alternative pathways PTDC/QUI-BIQ/119677/2010	Fundação para a Ciência e a Tecnologia
2011/06/15 - 2011/12/15	Controlled freezing to improve the stability and delivery of therapeutic proteins PTDC/EQU-EQU/104318/2008 Research Fellow Universidade de Lisboa Centro de Química Estrutural, Portugal	Fundação para a Ciência e a Tecnologia Concluded
2010/01/02 - 2011/03/31	Single-Molecule Detection of the Prion Protein: Characterization of Conformational Changes Involved in Prion Diseases PTDC/QUI/73027/2006 Scientific Initiation Fellow Universidade do Algarve, Portugal	Fundação para a Ciência e a Tecnologia Concluded

Publications

Journal article

Lopes, Carlos. "Stability of Protein Formulations at Subzero Temperatures by Isochoric Cooling". Journal of Pharmaceutical Sciences 109 1 (2020): 316-322. http://dx.doi.org/10.1016/j.xphs.2019.06.017. 10.1016/j.xphs.2019.06.017 Melo EP; Lopes C; Gollwitzer P; Lortz S; Lenzen S; Mehmeti I; Kaminski CF; Ron D; Avezov E. "TriPer, an optical probe tuned to the endoplasmic reticulum tracks changes in luminal H2O2.". (2017): http://europepmc.org/abstract/med/28347335. 10.1186/s12915-017-0367-5 Estrela N; Franquelim HG; Lopes C; Tavares E; Macedo JA; Christiansen G; Otzen DE; Melo EP. "Sucrose prevents protein fibrillation through compaction of the tertiary structure but hardly affects the secondary structure.". (2015): http://europepmc.org/abstract/med/26344410. 10.1002/prot.24921 Lopes, Carlos. "Live-cell FRET imaging reveals clustering of the prion protein at the cell surface induced by infectious prions". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2014): http://www.sciencedirect.com/science/article/pii/S0925443914000350/pdf?md5=b143495eabd2807a80df6d482b11a885&pid=1-s2.0-S0925443914000350-main.pdf. Rosa, M.; Lopes, C.; Melo, E.P.; Singh, S.K.; Geraldes, V.; Rodrigues, M.A.. "Measuring and modeling hemoglobin aggregation below the freezing temperature". Journal of Physical Chemistry B 117 30 (2013): 8939-8946. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881244021&partnerID=MN8TOARS. 10.1021/jp4035369 Lopes, Carlos. "Unfolding pathway of CotA-laccase and the role of copper on the prevention of refolding through aggregation of the unfolded state". Biochemical and Biophysical Research Communications 422 3 (2012): 442-446. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861938261&partnerID=MN8TOARS. 10.1016/j.bbrc.2012.05.011 Melo, E.P.; Estrela, N.; Lopes, C.; Matias, A.C.; Tavares, E.; Ochoa-Mendes, V.. "Compacting proteins: Pros and cons of osmolyte-induced folding". Current Protein and Peptide Science 11 8 (2010): 744-751. http://www.scopus.com/inward/record.url?eid=2-s2.0-79951728885&partnerID=MN8TOARS. 10.2174/138920310794557727