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I am graduated in Biochemistry at School of Sciences, University of Minho in 2018. In 2021, I concluded my Master's in Health Sciences at the Life and Health Sciences Research Institute (ICVS). My thesis dissertation was focused on the role of GSK-3 inhibition in lung homeostasis and injury. This work was published in a scientific journal (doi:10.3390/ijms25021279). From 2016 to 2020 I was a member of a project awarded (IF/00959/2014) in a competitive national call. From 2021 to 2022 I was an external collaborator of the ICVS. During this period, I focused my research interests on lung cell and molecular biology, aiming to contribute to bringing new knowledge that can advance the therapeutic strategies available in lung diseases. During this time I presented a poster orally at an international meeting, which abstract was published in a scientific journal. I am was a co-author of three oral conferences presented in international meetings. I am was a co-author of a published article (doi:10.3390/cells12030402). From 2022 to March 2023 I worked as researcher at Innovation and Development department of Mesosystem S.A. I focused my research on the extraction/purification of natural bioactive compounds from marine sources and by-products from the wine industry for use in cosmetic formulations, in line with the circular economy/industrial symbiosis. In this context, I was a member of an international award-winning project (MOD.PN.FRM.059.PT.V03), I was an internship tutor of two master students, I participated as co-author in four international oral communications, and I wrote a review article (doi:10.3390/ph16040592). I am currently a PhD student at the University of Trás-os-Montes and Alto Douro (UTAD) where we are focusing on polyphenol-based nanoparticles for targeted therapies of prostate cancer. At moment, I published a review article (doi:10.3390/biomedicines11123140) and I presented four oral communications in national and international conferences.
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Identification

Personal identification

Full name
Raquel Alexandra Gomes Fernandes

Citation names

  • Fernandes, Raquel

Author identifiers

Ciência ID
4F17-B17E-CD82
ORCID iD
0000-0003-4764-2580

Email addresses

  • rgfernandes@utad.pt (Professional)
  • raquel.f.0018@gmail.com (Personal)

Addresses

  • Vila Real, 4710-057, Vila Real, Vila Real, Portugal (Professional)

Websites

Knowledge fields

  • Medical and Health Sciences - Health Sciences
  • Natural sciences - Biological Sciences - Cell Biology
  • Natural sciences - Biological Sciences - Molecular Biology
  • Natural sciences - Biological Sciences - Biochemistry

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Advanced (C1) Advanced (C1) Upper intermediate (B2)
Spanish; Castilian Proficiency (C2) Proficiency (C2) Upper intermediate (B2) Proficiency (C2)
Education
Degree Classification
2023/10 - 2027
Ongoing
 Ciências Químicas e Biológicas (Doutoramento)
Universidade de Trás-os-Montes e Alto Douro, Portugal
2018 - 2021
Concluded
 Health Sciences (Mestrado)
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
"The role of GSK-3 inhibition in lung injury" (THESIS/DISSERTATION)
 18
2019/01 - 2019/05
Concluded
 Laboratory Animals Sciences - Category C program according to FELASA recommendations (Curso de mestrado (conclusão do curso de especialização))
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 16
2018/11 - 2019/05
Concluded
 Laboratory Rotation "Lung macrophage populations and their activation profile in bleomycin-induced pulmonary fibrosis" (Curso de mestrado (conclusão do curso de especialização))
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 18
2015 - 2018
Concluded
 Biochemistry (Licenciatura)
Universidade do Minho Escola de Ciências, Portugal
""Lung injury modulation by c-Met- expressing immune cells"" (THESIS/DISSERTATION)
 15
Affiliation

Science

Category
Host institution 		Employer
2022/09 - 2023/03 Researcher (Research) Mesosystem S.A, Portugal
2021/04 - 2022/09 Visiting Researcher (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Laboratório Associado ICVS 3B's, Portugal
(...)
2017/09 - 2018/09 Research Trainee (Research) Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
Laboratório Associado ICVS 3B's, Portugal
(...)

Others

Category
Host institution 		Employer
2024/01 - Current Doctoral Student Universidade de Trás-os-Montes e Alto Douro Centro de Investigação e de Tecnologias Agro-Ambientais e Biologicas, Portugal
2021/02 - 2022/08 Dental Assistant Dentolímia, Portugal
2021/02 - 2022/08 Dental clinic coordinator / Dental Assistant Hospital de São José, Portugal
Projects

Grant

Designation Funders
2022 - 2023 Physalia Physalis - Innovative and unexploited source of high added-value cosmetic products - 1.238.013 EUR
MOD.PN.FRM.059.PT.V03
Researcher
Mesosystem S.A, Portugal
 EEA and Norway Grants
Ongoing
2016 - 2020 Unravelling the key roles of tissue macrophages in lung morphogenesis and injury - 49.500 EUR
IF/00959/2014
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book
  1. Ana I.R.N.A. Barros; Campos, Joana; Fernandes, Raquel. Funcional Food. IntechOpen. 2023.
    Under revision • Assistant staff
Conference abstract
  1. Ana I.R.N.A. Barros; Campos, Joana; Fernandes, Raquel; Mónica Serra; Javier Fidalgo; Hugo Almeida; Ana Casas. "Fighting antibiotic resistance: giving a second life to natural compounds". Paper presented in The First International Conference on Antioxidants: Sources, Methods, Health Benefits and Industrial Applications, Barcelone, 2023.
    Accepted
  2. Mónica Serra; Fernandes, Raquel; Campos, Joana; Hugo Almeida; Javier Fidalgo; Ana Casas; Ana I.R.N.A. Barros. "Hyaluronic acid: new advances in optimising production for rejuvenation". Paper presented in 6th Edition of International Webinar on Aging and Rejuvenation, 2022.
  3. Fernandes, Raquel; Catarina Barbosa-Matos; Caroline Borges-Pereira; Sandra Costa. "Glycogen synthase kinase-3 inhibition by CHIR99021 promotes alveolar epithelial cell proliferation and lung regeneration in acute lung injury". Paper presented in Lung Research Conference 2021, 2021.
    Published • 10.1183/23120541.lsc-2021.88
Conference poster
  1. Fernandes R 4F17-B17E-CD82; Barbosa-Matos, Catarina; Caroline Borges-Pereira; Costa S. "Glycogen synthase kinase-3 inhibition by CHIR99021 promotes alveolar epithelial cell proliferation and lung regeneration in acute lung injury". Paper presented in 19th Lung Science Conference " Repair and regeneration in chronic lung disease and lung cancer", 2021.
  2. Libório-Ramos, Sofia; Catarina Barbosa-Matos; Caroline Borges-Pereira; Fernandes R F17-B17E-CD82; Costa S. "Pulmonary macrophages profile during the inflammatory phase of lung fibrosis". Paper presented in Champalimaud Research Symposium “Tissue Environment in Health and Disease, 2019.
Journal article
  1. Jorge Gomes Lopes Barros; Raquel Fernandes; Ana Abraão; Rui Dias Costa; Alfredo Aires; Irene Gouvinhas; Daniel Granato; Ana Novo Barros. "Characterization of Azorean Plant Leaves for Sustainable Valorization and Future Advanced Applications in the Food, Cosmetic, and Pharmaceutical Industries". Antioxidants (2024): https://doi.org/10.3390/antiox13030325.
    10.3390/antiox13030325
  2. Fernandes, Raquel; Barbosa-Matos, Catarina; Borges-Pereira, Caroline; Carvalho, Ana Luísa Rodrigues Toste de; Costa, Sandra. "Glycogen Synthase Kinase-3 Inhibition by CHIR99021 Promotes Alveolar Epithelial Cell Proliferation and Lung Regeneration in the Lipopolysaccharide-Induced Acute Lung Injury Mouse Model". International Journal of Molecular Sciences 25 2 (2024): 1279. http://dx.doi.org/10.3390/ijms25021279.
    Published • 10.3390/ijms25021279
  3. Fernandes, Raquel; Cátia Costa; Rúben Miguel Pereira Fernandes; Ana I. R. N. A. Barros. "Inflammation in Prostate Cancer: Exploring the Promising Role of Phenolic Compounds as an Innovative Therapeutic Approach". Biomedicines 11 12 (2023): https://www.mdpi.com/2227-9059/11/12/3140.
    Published
  4. Raquel Fernandes; Joana Campos; Mónica Serra; Javier Fidalgo; Hugo Almeida; Ana Casas; Duarte Toubarro; Ana I. R. N. A. Barros. "Exploring the Benefits of Phycocyanin: From Spirulina Cultivation to Its Widespread Applications". Pharmaceuticals (2023): https://doi.org/10.3390/ph16040592.
    10.3390/ph16040592
  5. Sofia Libório-Ramos; Catarina Barbosa-Matos; Raquel Fernandes; Caroline Borges-Pereira; Sandra Costa. "Interstitial Macrophages Lead Early Stages of Bleomycin-Induced Lung Fibrosis and Induce Fibroblasts Activation". Cells (2023): https://doi.org/10.3390/cells12030402.
    10.3390/cells12030402
  6. Fernandes, Raquel; Catarina Barbosa-Matos; Caroline Borges-Pereira; Ana Luísa Rodrigues Toste de Carvalho; Costa, Sandra. "Glycogen synthase kinase-3a/b isoforms inhibition by CHIR99021 promotes alveolar epithelial progenitor proliferation and repair in acute lung injury.". (2023):
    Submitted
  7. Catarina Barbosa-Matos; Caroline Borges-Pereira; Libório-Ramos, Sofia; Fernandes, Raquel; Costa, Sandra. "c-MET deletion attenuates bleomycin-induced pulmonary fibrosis by modulation of inflammatory recruitment.". (2023):
    Submitted
Thesis / Dissertation
  1. "The role of GSK-3 inhibition in lung injury". Master, 2021.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/12/11 Innovative therapeutic strategies against prostate cancer using grape stem-based gold nanoparticles I Seminar | PhD in Chemical and Biological Sciences
2023/11/22 Polyphenol-based gold nanoparticles for innovative targeted prostate cancer therapies Encontro Luso Galego de Química
2023/11/17 GRAPE STEM-BASED NANOPARTICLES FOR TARGETED PROSTATE CANCER THERAPIES AND BY-PRODUCT UPGRADE InoV4Agro Researchers Day
2023/10/25 Grape stem polyphenol-based nanoparticles for by-product recycling and innovative targeted prostate cancer therapies 3rd Edition of the Online Conference - Circular Economy: Make It Happen
(Portugal)
2023/06 A sustainable and innovative strategy on the treatment of wounds using natural bioactive compounds International Congress on Pharmaceutics and Novel Drug Delivery Systems
(London, United Kingdom)
2023/05 Fighting antibiotic resistance: giving a second life to natural compounds The First International Conference on Antioxidants: Sources, Methods, Health Benefits and Industrial Applications
(Barcelone, Spain)
2023/03 Traceability, authentication and sustainability of food matrices: A Spectroscopic overview 2nd Global Summit on Food Science and Technology
(Rome, Italy)
2022 Hyaluronic acid: new advances in optimising production for rejuvenation 6th Edition of International Webinar on Aging and Rejuvenation

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2018/02/17 - 2018/02/17 Participation and organization of the activity " Ciência p`ra que te quero| A tua casa é sustentável? Vamos preservar o património!" (2018/02/17)
Workshop
 Universidade do Minho Escola de Ciências, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2023/07/18 - 2023/07/20 Participation in a workshop
Workshop
 Plant Mediated Green Synthesis of Metal Based Nanoparticles
Nano Science & Technology Consortium, India
2023/06 - 2023/06 Participation in a webinar
Other
 Mouse and Rat Model Generation: The Essentials for Success
Taconic Biosciences Inc, United States
2023/03/10 - 2023/03/10 III International Webinar on Trends in Food Science, Technology, and Health
Other
 Women in Food Science Science- Sustainable proteins
University of Limerick, Ireland
2022/12/15 - 2022/12/16 Participation in a webinar
Seminar
 EIT Food Online Training Session DNA Analysis – Fast and Portable Methods
EIT Food iVZW, Belgium
2022/12 - 2022/12 EIT Food Online Training Session DNA Analysis – Fast and Portable Methods, webinar
Other
 EIT Food Online Training Session DNA Analysis- Fast and Portable Methods
2022/11/18 - 2022/11/19 Participation in an international conference
Congress
 LEGUMINA- Congresso de Alimentação Vegetariana
Faculdade de Medicina da Universidade Católica Portuguesa, Portugal
2022/10/27 - 2022/10/27 Webinar about medical devices regulation, inspection and licensing
Conference
 Novo Regulamento dos Dispositivos Médicos (UE) 2017/745: Inspeção e licenciamento
Infarmed Autoridade Nacional do Medicamento e Produtos de Saúde IP, Portugal
2022/10 - 2022/10 Specialized cell and evolution, webinar
Other
 Specialized Cell and Evolution
The American Society for Cell Biology, United States
2021/01/23 - 2021/01/23 Participation in training "Criatividade e Inovação Social"
Other
FNAJ – Federação Nacional das Associações Juvenis, Portugal
2020/09 - 2020/09 Participation in the webinar "International Covid-19 webinar: Current scenario, opportunities and challenges"
Universidade do Minho Escola de Medicina, Portugal
2020/09 - 2020/09 Health literacy, an emergent challenge. Contributors for behavior change, webinar
Centro Hospitalar e Universitário de Coimbra EPE, Portugal
2020/05 - 2020/05 Participation in the webinar "Vacinação e Covid19"
Universidade do Minho Escola de Medicina, Portugal
2019/12 - 2019/12 Participation in the scientific seminar "DEV BIO MED from biology to medicine and back"
Fundação Champalimaud, Portugal
2019/05 - 2019/05 Participation in the scientific seminar "Frontiers of research in ILD"
Universidade do Minho Escola de Medicina, Portugal
2019/01/10 - 2019/01/18 Participation in the project " Educations on environment & entrepreneurship", Cuetzalan, Mexico
Youthpass, Intercambios Juveniles, Mexico
2018 - 2018 Participation in the workshop "Comunicar Ciência- da investigação à indústria"
Universidade do Minho, Portugal
2017 - 2017 Participation in "VIII Jornadas de Bioquímica – 10 anos de percurso"
Universidade do Minho Escola de Ciências, Portugal
2016 - 2016 Participation in "VII Jornadas de Bioquímica – Ciência para a vida"
Universidade do Minho Escola de Ciências, Portugal
2016 - 2016 Participation in “IX Encontro nacional de estudantes de Bioquímica”
Universidade de Coimbra, Portugal

Association member

Society Organization name Role
2018/07/02 - 2018/07/30 Coordinadora Infantil y Juvenil de Tiempo Libre de Vallecas: Madrid, ES Participation in a volunteer project

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2024/01 - Current Ética e Ciência
2024/01/23 - 2024/01/25 Cromatografia e Espetrometria de Massa

Mentoring / Tutoring

Topic Student name
2022/10 - 2023/01 Valorization of by-products from the winery industry for the development of new cosmetic products Maria Beatriz Sanguedo Castro da Silva Oliveira
2022/10 - 2023/01 Innovative Process for the Production of Hyaluronic Acid from By-products of the Wine Industry Sara Ribeiro Peixoto
Distinctions

Other distinction

2023 Best oral presentation
2014 Scholastic excellence award
Escola Secundária de Ponte da Barca, Portugal
2013 Scholastic excellence award
Escola Secundária de Ponte da Barca, Portugal