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Ana Joana Borges Duarte completed her Master's in biology in 2008, and her Biology Degree in 2006, both from Faculty of Sciences (FCUP) - University of Porto (UP). She is currently attending the PhD in Biomedical Sciences from Instituto de Ciências Biomédicas Abel de Salazar (ICBAS, UP). She worked has a research fellow in the Lysosomal Storage Disorders R&D group (National Institute of Health Doutor Ricardo Jorge - INSA) since 2009, and in 2019 she signed a contract has Superior Technician to work in the same R&D group. Since 2015 she is also a group member of the Centre for Animal Science Studies (CECA, UP). Ana published 15 articles in peer-reviewed journals; has 1 book section published; supervised 1 work of course completion of LSc/BSc; and has received 8 awards and/or honors. In addition to her PhD project (Fabry disease: from iPS cells to Genomic Editing), she is currently Researcher in 3 projects. She was Principal Investigator in 1 project (Molecular and cellular defects of cystatin B - from cell to population), and was Research Fellow in 2 FCT funded projects. Works in the areas of Medical and Health Sciences, with emphasis on Medical Biotechnology (Gene-based Diagnostics and Therapeutic Interventions), as well as the area of Basic Medicine with emphasis on Human Genetics. In her curriculum Ciência Vitae the most frequent terms in the context of scientific and technological output are: Sphingolipidoses; Hereditary metabolic diseases; Lysosomal Storage Disorders; Ceramide; Cellular models; Lysosome; Genetic Diseases; Correction mechanisms; Induced Pluripotent Stem Cells; CRISPR/Cas; Fabry Disease; Gaucher Disease; Sphingolipidoses; Heart failure.
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Identification

Personal identification

Full name
Ana Joana Borges Duarte

Citation names

  • Duarte, Ana Joana

Author identifiers

Ciência ID
4F11-0EFD-0103
ORCID iD
0000-0002-6774-4886

Email addresses

  • ana.duarte@insa.min-saude.pt (Professional)

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Gene-based Diagnostics and Therapeutic Interventions
  • Medical and Health Sciences - Basic Medicine - Human Genetics

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
English Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
Spanish; Castilian Beginner (A1) Intermediate (B1) Beginner (A1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2017/07 - 2023/11
Ongoing
 Doutoramento em Ciências Biomédicas (Doutoramento)
Major in Genética Humana
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008
Concluded
 Mestrado em Biologia (Mestrado)
Universidade do Porto Faculdade de Ciências, Portugal
"Estudo de mosaicismo em casos de Restrição de Crescimento Intra-Uterino por Hibridação Genómica Comparativa" (THESIS/DISSERTATION)
 17 Valores
2006
Concluded
 Biologia (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal
"Mecanismos Neurohumorais e Endoteliais na Insuficiência Cardíaca Diastólica" (THESIS/DISSERTATION)
 14 Valores
Affiliation

Other Careers

Category
Host institution 		Employer
2019/02/01 - Current Técnico Superior (Técnico Superior) Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Saúde Pública Dr. Gonçalves Ferreira, Portugal

Others

Category
Host institution 		Employer
2017/07 - Current Estudante de Doutoramento Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Saúde Pública Dr. Gonçalves Ferreira, Portugal
2015/01/02 - Current I&D group member Universidade do Porto Centro de Estudos de Ciencia Animal, Portugal
2020/04 - 2023/12 Colaborador na implementação dos testes moleculares de SARS-Cov-2 no INSA Porto Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Saúde Pública Dr. Gonçalves Ferreira, Portugal
2016/05/02 - 2017/08/31 FCT Research Fellow in the project “Cellular models for the study of lysosomal dysfunction and correction mechanisms (CeMoLy)”, with the reference PTDC/BIM-MEC/4762/2014. Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Saúde Pública Dr. Gonçalves Ferreira, Portugal
2015/09/14 - 2016/04/29 Collaborator I&D in the Lysosomal Storage Disorders group at Instituto Nacional de Saúde Dr. Ricardo Jorge (INSA, IP), Porto. Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Saúde Pública Dr. Gonçalves Ferreira, Portugal
2013/04/01 - 2015/07/31 Grant winner and Investigator of the project "Molecular and cellular defects of cystatin B - from cell to population", Genzyme Investigation Grant 2013. http://www.spdm.org.pt/bolsas/bolsas-atribuida Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Saúde Pública Dr. Gonçalves Ferreira, Portugal
2013/02/04 - 2013/03/15 Colaboration, organization and participation in the International event "Brain Awareness Week" from Dana Foundation, USA. http://www.dana.org/baw/reportdetail.aspx?id=109535 Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Genética Médica Jacinto de Magalhães, Portugal
2012/06/01 - 2012/12/31 Collaborator on the project “Prognosis and prevention in a few inherited diseases existing in the Portuguese population” (PIC/IC/82822/2007). Research in Lysosomal Storage Disorders. Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Genética Médica Jacinto de Magalhães, Portugal
2009/06/01 - 2012/05/31 FCT Research Fellow: FCT PIC/IC/82822/2007 “Prognosis and prevention in a few inherited diseases existing in the Portuguese population ”. Area: Lysosomal Storage Disorders. Four peer-reviewed articles Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Genética Médica Jacinto de Magalhães, Portugal
2007/01/02 - 2008/12/31 I&D group member Universidade do Porto Unidade de Investigação e Desenvolvimento Cardiovascular, Portugal
2007/10/01 - 2008/12/18 Master in Biology: Thesis title: “Estudo de Mosaicismo Cromossómico em casos de Restrição de Crescimento Intra-Uterino por Hibridação Genómica Comparativa”. Three works presented in conferences. Universidade do Porto Faculdade de Medicina, Portugal
2007/05/07 - 2008/05/18 Diagnosis in Cytogenetics: - Karyotype analysis - G banding - Cell culture - FISH (Fluorescence in situ hybridization) Universidade do Porto Faculdade de Medicina, Portugal
2006/08/14 - 2007/04/27 Postgraduate training: I continued the studies with endothelin -1 and initiated studies with urocortin - 2 in papillary muscles from New Zealand rabbit. Co-author of one article. Eight conference pape Universidade do Porto Faculdade de Medicina, Portugal
2006/02/01 - 2006/07/14 Academic training: Thesis title: “Mecanismos Neurohumorais e Endoteliais na Insuficiência Cardíaca Diastólica” In vitro evaluation of endothelin-1 action in papillary muscles from New Zealand rabbit. Universidade do Porto Faculdade de Medicina, Portugal
Projects

Grant

Designation Funders
2019/01 - Current Genetic Substrate Reduction Therapy for Mucopolysaccharidoses Toward a siRNA-containing nanoparticle targeted to brain cells
2019DGH1629/SPDM2018I&D
Researcher
Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Saúde Pública Dr. Gonçalves Ferreira, Portugal
 Sociedade Portuguesa de Doenças Metabólicas (Portuguese Society for Metabolic Disorders)
Concluded
2017/09/01 - Current Fabry disease: from iPS cells to Genomic Editing
SFRH/BD/118009/2016
PhD Student Fellow
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2023/06 - 2025/03 ModellingMLII - New models for the most frequent Mucolipidosis II-causing mutation using iPSCs and zebrafish: a crucial step towards the development of new therapies
2022.03836.PTDC
Researcher
Universidade do Porto Centro de Estudos de Ciencia Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2023/03/01 - 2024/09/30 Development of a Genetic Substrate Reduction Therapy for MPS III using Antisense Oligonucleotides as therapeutic agents (ASOs2cureMPSIII)
-
Researcher
Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal
 Fundação para a Ciência e a Tecnologia
Ongoing
2013/05/02 - 2014/12/31 Cystatin B: From cell to population
Bolsa SPDM/Genzyme 2012
Principal investigator
Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Saúde Pública Dr. Gonçalves Ferreira, Portugal
 Genzyme Corporation
Concluded

Contract

Designation Funders
2020/01/01 - Current Genetic Substrate Reduction Therapy for Mucopolysaccharidoses - Toward a siRNA-containing nanoparticle targeted to brain cells
2019DGH1656/SCF2019I&D
Researcher
Sanfilipo Childrens Foundation, Australia
 Sanfilipo Childrens Foundation
Ongoing
2023/03/01 - 2025/02/28 Development of a Genetic Substrate Reduction Therapy for MPS III using Antisense Oligonucleotides as therapeutic agents
2022.04667.PTDC
10.54499/2022.04667.PTDC
Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal

Universidade do Porto Centro Interdisciplinar de Investigação Marinha e Ambiental, Portugal

Centro Hospitalar Universitário de Santo António, Portugal

Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal

Centro Hospitalar Universitário Lisboa Norte EPE, Portugal

Centro Hospitalar Universitário de São João, Portugal

Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação para a Ciência e a Tecnologia
Ongoing
2022/01/01 - 2023 Neurological disease modeling for Sanfilippo: a key step towards understanding and treating a rare genetic disorder
EXPL/BTM-SAL/0659/2021
Researcher
Universidade do Porto Centro de Estudos de Ciencia Animal, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/05/01 - 2020/01/31 Cellular models for the study of lysosomal dysfunction and correction mechanisms (CeMoLy) - Modelos celulares para o estudo de mecanismos de disfunção e correção lisossomal
PTDC/BIM-MEC/4762/2014
Research Fellow
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal

Universidade do Algarve, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2019/01/01 - 2019/12/31 Center for the Study of Animal Science
UID/Multi/00211/2019
Universidade do Porto Centro de Estudos de Ciencia Animal, Portugal

Universidade do Porto Instituto de Ciências Tecnologias e Agroambiente, Portugal
Fundação para a Ciência e a Tecnologia
Concluded
2009/01/01 - 2012/12/30 Prognóstico e prevenção em algumas doenças hereditárias existentes na população portuguesa
PIC/IC/82822/2007
Research Fellow
Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Amaral, Olga; Duarte, Ana; Ribeiro, Diogo; Santos, Renato; Bragança, José. "Applications of iPSCs in Gaucher Disease and other rare sphingolipidoses". In iPSCs - State of the Science, 197-224. Elsevier, 2022.
    Published • 10.1016/b978-0-323-85767-3.00001-3
Conference abstract
  1. Duarte, Ana Joana. "Unverricht-Lundborg disease: development of splicing therapeutic approaches for a patient with an homozygous mutation in the cystatin B gene". Paper presented in 9th Annual Meeting of the Oligonucleotide Therapeutics Society Annual Meeting, Nápoles, 2013.
    Published
  2. Duarte, Ana Joana. "Genetic variation in a gene involved in glycosphingolipid biosynthesis". Paper presented in American Society of Human Genetics, 2013.
    Published
  3. Duarte, Ana Joana. "Application of Touch FISH as an additional tool in the study of spontaneous abortions". Paper presented in Chromosome Research, 2009.
    Published
  4. Duarte, Ana Joana. "Nitric oxide and prostaglandins - key downstream modulators of endothelin-1 induced incrase in myocardial distensibility". Paper presented in inter Meeting on Translational Basic Science of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) - From Cardiac Adaptation to Failure and Back 2007, 2007.
    Published
  5. Duarte, Ana Joana. "Efeitos Miocárdicos da Urocortina 2". Paper presented in Revista Portuguesa de Cardiologia, 2007.
    Published
  6. Duarte, Ana Joana. "Evidência funcional para a existência de interacção dos receptores ETA e ETB no coração". Paper presented in Revista Portuguesa de Cardiologia, 2007.
    Published
  7. Duarte, Ana Joana. "O aumento da distensibilidade miocárdica induzido pela endotelina-1 depende da libertação endotelial de NO e prostaglandinas". Paper presented in Revista Portuguesa de Cardiologia, 2006.
    Published
  8. Duarte, Ana Joana. "Impaired systolic and diastolic myocardial response to ET-1 and angiotensin II in heart failure". Paper presented in European Journal of Heart Failure, 2006.
    Published
  9. Duarte, Ana Joana. "NO and prostaglandins are required for the increase in myocardial distensibility induced by ET-1". Paper presented in European Journal of Heart Failure, 2006.
    Published
  10. Duarte, Ana Joana. "Impaired systolic and diastolic myocardial response to ET-1 and angiotensin II in heart failure". Paper presented in Circulation, 2006.
    Published
  11. Duarte, Ana Joana. "Endothelin-1 increases myocardial distensibility through nitric oxide and prostaglandins". Paper presented in Circulation, 2006.
    Published
  12. Duarte, Ana Joana. "Atenuação da resposta miocárdica à endotelina-1 e à angiotensina II com evidência de disfunção endotelial endocárdica na insuficiência cardíaca". Paper presented in Revista Portuguesa de Cardiologia, 2005.
    Published
  13. Graw, G.. "Evidence for the existence of supersymmetry in atomic nuclei". Paper presented in Journal of Hypertension, 2000.
    Published • 10.1063/1.1361367
Conference paper
  1. Duarte, Ana Joana. "Unverricht-Lundborg disease. Report of a new mutation.". 2011.
    Published • 10.1111/j.1528-1167.2011.03207.x
  2. BRASSILVA, C; DUARTE, A; MONTEIROSOUSA, D; LEITEMOREIRA, A. "154 Urocortin 2 acutely decreases myocardial stiffness". 2008.
    10.1016/s1567-4215(07)60110-6
  3. BRASSILVA, C; MONTEIROSOUSA, D; DUARTE, A; FONTESSOUSA, A; LEITEMOREIRA, A. "348 NO and prostaglandins are required for the increase in myocardial distensibility induced by ET-1". 2007.
    Published • 10.1016/s1567-4215(06)80210-9
  4. BRASSILVA, C; MONTEIROSOUSA, D; DUARTE, A; LEITEMOREIRA, A. "671 Functional evidence for the existence of ETA-ETB receptor crosstalk in the heart". 2007.
    10.1016/s1567-4215(07)60406-8
Conference poster
  1. Moreira, Luciana Vaz; Moutinho, Maria Eduarda; Coutinho, Maria Francisca; Duarte, Ana Joana; Gonçalves, Mariana; Matos, Liliana; Santos, Juliana Inês; et al. "Advances and challenges in generating new models for the rare genetic disease Mucolipidosis type II.". Paper presented in ESGCT/SITGEC Collaborative Congress, 2024.
  2. Duarte, Ana Joana; Moreira, Luciana Vaz; Bragança, José; Amaral, Olga. "Development of a Fabry Disease cell model using Gene Editing.". Paper presented in SSIEM 2024 Annual Symposium, 2024.
  3. Duarte, Ana Joana; Moreira, Luciana Vaz; Bragança, José; Amaral, Olga. "Development of a Knockout cell line for Fabry Disease through CRISPR/Cas9 system". Paper presented in III Meeting Al4animals, 2024.
  4. Moutinho, Maria Eduarda; Duarte, Ana Joana; Gonçalves, Mariana; Matos, Liliana; Coutinho, Maria Francisca; Amaral, Olga; Alves, Sandra; Moreira, Luciana Vaz. "Correcting the most frequent pathogenic variant causing Mucolipidosis type II with CRISPR/Cas9". Paper presented in III AL4AnimalS Meeting, 2024.
  5. Carvalho, Sofia; Santos, Juliana Inês; Moreira, Luciana Vaz; Duarte, Ana Joana; Gaspar, Paulo; Rocha, Hugo; Encarnação, Marisa; et al. "Models Matter: exploring baby teeth as a source of stem cells for translational research in Mucopolysaccharidoses". Paper presented in III Meeting Al4animals, 2024.
  6. Almeida Barbosa, Matilde; Santos, Juliana Inês; Carvalho, Sofia; Moreira, Luciana Vaz; Moutinho, Maria Eduarda; Duarte, Ana Joana; Gaspar, Paulo; et al. "A Step Closer To a Much Desired Cure: Human Induced Pluripotent Stem Cell Lines as Tools in Understanding and Treating MPS III". Paper presented in III Meeting Al4animals, 2024.
  7. Almeida, Matilde Barbosa; Carvalho, Sofia; Santos, Juliana Inês; Moreira, Luciana Vaz; Moutinho, Maria Eduarda; Duarte, Ana Joana; Gaspar, Paulo; Coutinho, Maria Francisca; Alves, Sandra. "Induced Pluripotent Stem Cell Lines as Tools to Understand and Treat MPS III". Paper presented in 20º Simpósio Internacional da SPDM, 2024.
  8. Duarte, Ana Joana. "Prime Editing testing to correct a Fabry Disease nonsense mutation". Paper presented in 27ª Reunião Anual da Sociedade Portuguesa de Genética Humana, 2023.
  9. Duarte, Ana Joana. "Gene Editing in Fabry Disease: A Strategy Delineation". Paper presented in 26ª Reunião Anual da Sociedade Portuguesa de Genética Humana, 2023.
  10. Amaral, Olga; Duarte, Ana Joana. "Models of Lysosomal Storage Diseases". Paper presented in European Society of Human Genetics, 2023.
  11. Amaral, Olga; Duarte, Ana Joana. "Prospective application of genomics in cell models". Paper presented in Genetics Week 2023 - Labroots, 2023.
  12. Duarte, Ana Joana. "The disease modelling value of a folklore FAIRYtale: SHEDing light over a special group of genetic disorders". Paper presented in 2th AL4AnimalS Meeting, 2023.
  13. Moreira, L; Duarte, Ana Joana. "Pluripotent cells and zebrafish: two complementary platforms for modelling Lysosomal Storage Disorders". Paper presented in Delivery of Antisense RNA Therapies (DARTER) Final Meeting, COST ACTION CA17103, 2023.
  14. Duarte, Ana Joana. "Gene editing in Fabry disease: A strategy delineation from first steps to future perspectives". Paper presented in 26.ª Reunião Anual da Sociedade Portuguesa de Genética Humana, 2022.
  15. Moreira, L; Duarte, Ana Joana. Corresponding author: Moreira, L. "Pluripotent cells and zebrafish: two complementary platforms for modelling Lysosomal Storage Disorders". Paper presented in CIISA Congress 2022: Innovation in Animal, Veterinary and Biomedical Research, 2022.
  16. Duarte, Ana Joana. "iPSCs-derived Cardiomyocytes and Future Perspectives". Paper presented in CIISA Congress 2022: Innovation in Animal, Veterinary and Biomedical Research, 2022.
  17. Duarte, Ana Joana. "iPSCs-derived Cardiomyocytes and Future Perspectives". Paper presented in Dia do Jovem investigador do INSA, 2022.
  18. Duarte, Ana Joana. "When folklore meets science: the 21st century baby teeth collector that is helping us SHED light over rare genetic disorders". Paper presented in 26ª Reunião Anual da Sociedade Portuguesa de Genética Humana, 2022.
  19. Duarte, Ana Joana. "The disease modelling value of baby teeth: A new way to unlock knowledge about a special group of genetic disorders". Paper presented in Dia do Jovem Investigador do Instituto Nacional de Saúde Dr. Ricardo Jorge, 2022.
  20. Duarte, Ana Joana. "Help come from unexpected places: how a tiny fairy and tropical fish may help us model Mucopolysaccharidosis type III". Paper presented in 24th ESGLD Workshop and Graduate Course, 2022.
  21. Moreira, L; Duarte, Ana Joana. "Urine Stem Cells as a potential in vitro model for Mucolipidosis type II". Paper presented in 24th ESGLD Workshop and Graduate Course, 2022.
  22. Moreira, L; Duarte, Ana Joana. Corresponding author: Moreira, L. "Urine Stem Cells as a potential in vitro model for Mucolipidosis type II". Paper presented in International Meeting of the Portuguese Society of Genetics, 2022.
  23. Duarte, Ana Joana. "Cell lines for the study of Lysosomal Storage Diseases: conservation and identity". Paper presented in Workshop Sphingolipids in Health and Disease, 2022.
  24. Duarte, Ana Joana; Ribeiro, Diogo; Moreira, Luciana; Amaral, Olga. Corresponding author: Amaral, Olga. "Can cell-type specific variability be involved in a rare variant of Unverricht-Lundborg? Investigation with iPSCs generated models". Paper presented in 25ª Reunião Anual da SPGH, 2021.
  25. Ribeiro, Diogo; Amaral, Olga; Encarnação, Marisa; Silva, Lisbeth; Alves, Sandra. Corresponding author: Amaral, Olga. "Preliminary characterization of lysosomal-related genes in two Tay-Sachs variant B1 fibroblast cell lines". Paper presented in 25ª Reunião Anual da SPGH, 2021.
  26. Maria Francisca Coutinho; Alves, Sandra; Ribeiro, Diogo; Santos, Juliana Inês; Carvalho, Sofia; Gaspar, Paulo; Matos, Liliana; et al. "The 2020S tooth fairy: from loose tooth to neuronal cell cultures, an innovative method to model neurologic lysosomal storage diseases in vitro". Paper presented in 25ª Reunião Anual da SPGH, 2021.
  27. Ribeiro, Diogo; Amaral, Olga. "Future perspectives using Lysosomal Storage Disease iPSCs models and gene editing therapy". Paper presented in Encontro com a Ciência e a Tecnologia em Portugal, 2021.
  28. Ribeiro, Diogo; Amaral, Olga. "From Lysosomal Storage Disease iPSCs models to gene editing therapy: future perspectives". Paper presented in Oligonucleotide Tecnologies and Therapieutics, 2021.
  29. Ribeiro, Diogo; Amaral, Olga. "Constructing a cardiac cell model from a patient with Fabry Disease". Paper presented in Labroots: 9th Genetics Virtual Week 2021, 2021.
  30. Duarte, Ana Joana. "A fisrt step to open the neuronal box of Gaucher Disease: neural progenitor cells". Paper presented in 24ª Reunião Anual da Sociedade Portuguesa de Genética Humana, 2020.
  31. Duarte, Ana Joana. "Induced Pluriopotent Stem Cells Derived Cardiomyocytes from a patient with Fabry Disease: a work in process cell model". Paper presented in 24ª Reunião Anual da Sociedade Portuguesa de Genética Humana, 2020.
  32. Duarte, Ana Joana. "What about the host? A possible answer using iPSCs". Paper presented in Coronavirus Virtual Webinar Series - Labroots, 2020.
  33. Duarte, Ana Joana. "Induced pluripotent stem cells as genetic disease models". Paper presented in 3rd Annual 2020 Cannabis Sciences Virtual Event - Labroots, 2020.
  34. Duarte, Ana Joana. "The key to open the neuronal box of Tay Sachs disease variant B1: cellular models". Paper presented in Segundo Encontro do Doutoramento em Ciências Biomédicas do ICBAS, 2019.
  35. Duarte, Ana Joana. "Gaucher disease and iPSCs: what does the future hold?". Paper presented in 13th European Working Group on Gaucher Disease Congress (EWGGD 2019), 2019.
  36. Duarte, Ana Joana. "From fibroblasts to cardiomyocytes in lysosomal storage disorders". Paper presented in 15th International Symposium SPDM, 2019.
  37. Duarte, Ana Joana. "First steps to generate a new Tay Sachs disease variant B1 cellular model". Paper presented in 15th International Symposium SPDM, 2019.
  38. Duarte, Ana Joana. "CRISPR/Cas in iPSCs from sphingolipidoses patients". Paper presented in 5th Annual WORLDSymposium 2019, 2019.
  39. Duarte, Ana Joana. "Upstream of precise disease models for better downstream decision making". Paper presented in First International Congress on Advanced Treatments in Rare Diseases (RARE2018), 2018.
  40. Duarte, Ana Joana. "From iPSCs to Gene Editing in Lysosomal Storage Disorders". Paper presented in Labroots Genetics and Genomics 2018, 2018.
  41. Duarte, Ana Joana. "Induced Pluripotent Stem Cells differentiation and characterization using Fabry Disease as a model of Lysosomal Storage Disorders". Paper presented in 1st Meeting of the Students of the 3CCB ICBAS, 2018.
  42. Duarte, Ana Joana. "Science communication: a matter of shared experiences". Paper presented in 21ª Reunião Anual Sociedade Portuguesa de Genética Humana, 2017.
  43. Duarte, Ana Joana. "Induced Pluripotent Stem Cells: from fibroblast to disease models". Paper presented in 21ª Reunião Anual Sociedade Portuguesa de Genética Humana, 2017.
  44. Duarte, Ana Joana. "Gene editing in Lysosomal Diseases". Paper presented in 8th annual Clinical Diagnostics & Research – Labroots, 2017.
  45. Duarte, Ana Joana. "Difficulties obtaining iPSCs from scratch". Paper presented in European Human Genetics Conference 2017, 2017.
  46. Duarte, Ana Joana. "Inducing a new start". Paper presented in 2º Dia do Jovem Investigador do Instituto Nacional de Saúde Doutor Ricardo Jorge, 2017.
  47. Duarte, Ana Joana. "To CRISPR or not to CRISPR". Paper presented in The 3rd CRISPR Congress, 2017.
  48. Duarte, Ana Joana. "CSTB: from cell to population". Paper presented in 12th SPDM symposium, 2016.
  49. Duarte, Ana Joana. "Preliminary results regarding the cellular characterization of normal and mutant cystatin B". Paper presented in Meeting da Sociedade Portuguesa de Bioquímica, 2014.
  50. Duarte, Ana Joana. "Cellular characterization of normal and mutant cystatin B". Paper presented in XVIII Congress of the Portuguese Biochemical Society, 2014.
  51. Duarte, Ana Joana. "Unverricht-Lundborg disease: desenvolvimento de uma nova abordagem terapêutica no caso de um doente homozygótico para uma mutação no gene da cistatin B". Paper presented in Simpósio dedicado às Doenças Raras II, 2014.
  52. Duarte, Ana Joana. "Genetic variation in a gene involved in glycosphingolipid biosynthesis". Paper presented in 63rd Annual Meeting of The American Society of Human Genetics, 2013.
  53. Duarte, Ana Joana. "Unverricht-Lundborg disease: development of splicing therapeutic approaches for a patient with an homozygous mutation in the cystatin B gene". Paper presented in 9th Annual Meeting of the Oligonucleotide Therapeutics Society, 2013.
  54. Duarte, Ana Joana. "Study of Cellular Localization of Cystatin B in Unverricht-Lundborg Disease". Paper presented in IX International Symposium of SPDM, 2013.
  55. Duarte, Ana Joana. "Genetic variation in a common biomarker encoded by CHIT1". Paper presented in 8th Annual Lysosomal Disease Network World Symposium 2012, 2012.
  56. Duarte, Ana Joana. "Lack of Cystatin B protein as a cause of Myoclonic Epilepsy". Paper presented in 8th Annual Lysosomal Disease Network World Symposium 2012, 2012.
  57. Duarte, Ana Joana. "Genetic Variation in CHIT1". Paper presented in VIII Simpósio Internacional da Sociedade Portuguesa de Doenças Metabólicas, 2011.
  58. Offutt, A.J.. "Characterization of a common IDUA mutation in the Portuguese population". Paper presented in VIII Simpósio Internacional da Sociedade Portuguesa de Doenças Metabólicas, 2011.
    10.1109/test.1994.528535
  59. Duarte, Ana Joana. "Allelic frequency of G102S and A442G CHIT1 in the Portuguese population". Paper presented in 18th European Study Group on Lysosomal Diseases Workshop, 2011.
  60. Duarte, Ana Joana. "New splicing mutation in the Cystatin B Gene". Paper presented in 18th European Study Group on Lysosomal Diseases Workshop, 2011.
  61. Duarte, Ana Joana. "Study of the p.W402X mutation frequency of the lysosomal a-L-iduronidase gene in the Portuguese population". Paper presented in XVII Congresso Nacional de Bioquímica, 2010.
  62. Duarte, Ana Joana. "New splicing mutation in cystatin B gene.". Paper presented in New splicing mutation in cystatin B gene., 2010.
  63. Duarte, Ana Joana. "Study of CHIT1 Single Nucleotide Polymorphisms in Portuguese controls". Paper presented in The EMBO meeting 2010, 2010.
  64. Duarte, Ana Joana. "Mutational analysis of the EPM1 gene in a Portuguese family". Paper presented in The EMBO meeting 2010, 2010.
  65. Wu, Weidong. "Allelic Discrimination of the Hexosaminidase A c.533G>A mutation.". Paper presented in The EMBO meeting 2010, 2010.
    10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5771
  66. Duarte, Ana Joana. "Study of mutation impact on lysosomal proteins using computational analysis". Paper presented in The Genetics Society of America Conferences, Genetics 2010: model organisms to human biology, 2010.
  67. Zhao, Sha; Wang, Ya; Bie, Beibei; Xu, Le; Bai, Hong. "Study on the Genetic Diversity of Reticulitermes Aculabialis". Paper presented in The Genetics Society of America Conferences, Genetics 2010: model organisms to human biology, 2010.
    10.5220/0008188402550259
  68. Hopwood, John J.. "Preliminary “in silico” analysis of mutations in Lysosomal Storage Diseases". Paper presented in VI Simpósio Da Sociedade Portuguesa De Doenças Metabólicas, 2009.
    10.1100/tsw.2002.360
  69. Duarte, Ana Joana. "Application of Touch FISH as na additional tool in the study of spontaneous abortions.". Paper presented in 7th European Cytogenetics Conference, 2009.
  70. Duarte, Ana Joana. "Duplications with terminal deletions". Paper presented in VIII Jornadas Internacionais de Diagnóstico Pré-Natal, 2008.
  71. Duarte, Ana Joana. "Double and triple chromosomal abnormalities in spontaneous abortions". Paper presented in III Jornadas Internacionais de Diagnóstico Pré-Natal, 2008.
  72. Duarte, Ana Joana. "Urocortin 2 Acutely Increases Diastolic Distensibility". Paper presented in Scientific Sessions of the American Heart Association 2007, 2007.
  73. Duarte, Ana Joana. "Urocortin 2 as a novel neurohumoral modulator of diastolic function.". Paper presented in European Society of Cardiology Congress 2007, 2007.
  74. Duarte, Ana Joana. "Functional evidence for the existence of ETA-ETB receptor crosstalk in the heart". Paper presented in European Society of Cardiology Congress 2007, 2007.
  75. Duarte, Ana Joana. "Functional evidence for the existence of ETA and ETB receptor crosstalk in the heart". Paper presented in Seventeenth European Meeting on Hypertension, 2007.
  76. Duarte, Ana Joana. "Urocortin 2 acutely decreases myocardial stiffness". Paper presented in Heart Failure 2007, 2007.
  77. Duarte, Ana Joana. "Functional evidence for the existence of ETA and ETB receptor crosstalk in the heart". Paper presented in Heart Failure 2007, 2007.
  78. Duarte, Ana Joana. "Evidência funcional para a existência de interacção dos receptores ETA e ETB no coração". Paper presented in XXVIII Congresso Português de Cardiologia, 2007.
  79. Duarte, Ana Joana. "Endothelin-1 increases myocardial distensibility through nitric oxide prostaglandins release". Paper presented in 79th Scientific Sessions of the American Heart Association 2006, 2006.
  80. Duarte, Ana Joana. "Disturbed myocardial response to endothelin-1 and angiotensin II in heart failure". Paper presented in 79th Scientific Sessions of the American Heart Association 2006, 2006.
  81. Duarte, Ana Joana. "NO and prostaglandins are required for the increase in myocardial distensibility induced by ET-1". Paper presented in Heart Failure 2006, 2006.
  82. Duarte, Ana Joana. "Impaired systolic and diastolic myocardial response to ET-1 and Ang II in heart failure". Paper presented in Heart Failure 2006, 2006.
  83. Duarte, Ana Joana. "Atenuação da resposta miocárdica à endotelina-1 e à angiotensina II com evidência de disfunção endotelial endocárdica na insuficiência cardíaca". Paper presented in XXVII Congresso Português de Cardiologia, 2006.
Journal article
  1. Santos, Juliana Inês; Gonçalves, Mariana; Almeida, Matilde Barbosa; Rocha, Hugo; Duarte, Ana Joana; Matos, Liliana; Moreira, Luciana Vaz; et al. "mRNA Degradation as a Therapeutic Solution for Mucopolysaccharidosis Type IIIC: Use of Antisense Oligonucleotides to Promote Downregulation of Heparan Sulfate Synthesis". International Journal of Molecular Sciences 26 3 (2025): 1273. https://doi.org/10.3390/ijms26031273.
    Open access • Published • 10.3390/ijms26031273
  2. Carvalho, Sofia; Santos, Juliana Inês; Moreira, Luciana; Duarte, Ana Joana; Gaspar, Paulo; Rocha, Hugo; Encarnação, Marisa; et al. "Modeling Lysosomal Storage Disorders in an Innovative Way: Establishment and Characterization of Stem Cell Lines from Human Exfoliated Deciduous Teeth of Mucopolysaccharidosis Type II Patients". International Journal of Molecular Sciences 25 6 (2024): 3546. https://doi.org/10.3390/ijms25063546.
    Published • 10.3390/ijms25063546
  3. Carvalho, Sofia; Moreira, Luciana; Santos, Juliana Inês; Gaspar, Paulo; Gonçalves, Mariana; Matos, Liliana; David, Hugo; et al. "Help Comes from Unexpected Places: How a Tiny Fairy and a TropicalFish may help us Model Mucopolysaccharidoses". Endocrine, Metabolic & Immune Disorders - Drug Targets 24 (2023): http://dx.doi.org/10.2174/0118715303277318231024055425.
    10.2174/0118715303277318231024055425
  4. Amaral, Olga; Martins, Mariana; Oliveira, Ana Rita; Duarte, Ana Joana; Mondragão-Rodrigues, Inês; Macedo, M. Fátima. "The Biology of Lysosomes: From Order to Disorder". Biomedicines 11 1 (2023): 213. http://dx.doi.org/10.3390/biomedicines11010213.
    10.3390/biomedicines11010213
  5. Duarte, Ana; Ribeiro, Diogo; Moreira, Luciana; Amaral, Olga. "In Silico Analysis of Missense Mutations as a First Step in Functional Studies: Examples from Two Sphingolipidoses". International Journal of Molecular Sciences 19 11 (2018): 3409. http://dx.doi.org/10.3390/ijms19113409.
    10.3390/ijms19113409
  6. Matos, Liliana; Duarte, Ana; Ribeiro, Diogo; Chaves, João; Amaral, Olga; Alves, Sandra. "Correction of a Splicing Mutation Affecting an Unverricht-Lundborg Disease Patient by Antisense Therapy". Genes 9 9 (2018): 455. http://dx.doi.org/10.3390/genes9090455.
    10.3390/genes9090455
  7. Duarte, Ana Joana; Ribeiro, Diogo; Oliveira, Pedro; Amaral, Olga. "Mutation Frequency of Three Neurodegenerative Lysosomal Storage Diseases: From Screening to Treatment?". Archives of Medical Research 48 3 (2017): 263-269. http://dx.doi.org/10.1016/j.arcmed.2017.04.001.
    10.1016/j.arcmed.2017.04.001
  8. Duarte, Ana Joana; Ribeiro, Diogo; Chaves, João; Amaral, Olga. "Characterization of a rare Unverricht–Lundborg disease mutation". Molecular Genetics and Metabolism Reports 4 (2015): 68-71. http://dx.doi.org/10.1016/j.ymgmr.2015.07.005.
    10.1016/j.ymgmr.2015.07.005
  9. Duarte, Ana Joana. "Characterization of a rare Unverricht-Lundborg disease mutation". Molecular Genetics and Metabolism Reports (2015):
    doi:10.1016/j.ymgmr.2015.07.005
  10. Duarte, Ana Joana; Ribeiro, Diogo; Amaral, Olga. "CHIT1 genetic defects in the Portuguese population". Blood Cells, Molecules, and Diseases 50 1 (2013): 50-52. http://dx.doi.org/10.1016/j.bcmd.2012.08.008.
    10.1016/j.bcmd.2012.08.008
  11. Diogo Ribeiro; Ana Cardoso; Ana Joana Duarte; Luis Vieira; Olga Amaral. "Efficient IDUA Gene Mutation Detection with Combined Use of dHPLC and Dried Blood Samples". ISRN Molecular Biology 2013 (2013): 1-4. https://doi.org/10.1155/2013/451298.
    10.1155/2013/451298
  12. Duarte, Ana Joana. "Efficient IDUA Gene Mutation Detection with Combined Use of dHPLC and Dried Blood Samples". ISRN Molecular Biology (2013): http://www.hindawi.com/journals/isrn/2013/451298/.
    http://dx.doi.org/10.1155/2013/451298
  13. Pinto, Eugénia; Freitas, Joel; Duarte, Ana Joana; Ribeiro, Isaura; Ribeiro, Diogo; Lima, J. Lopes; Chaves, João; Amaral, Olga. "Unverricht–Lundborg disease: Homozygosity for a new splicing mutation in the cystatin B gene". Epilepsy Research 99 1-2 (2012): 187-190. http://dx.doi.org/10.1016/j.eplepsyres.2011.11.004.
    10.1016/j.eplepsyres.2011.11.004
  14. Duarte, Ana; Ribeiro, Diogo; Amaral, Olga. "Genetic Variation in a Common Biomarker Encoded By CHIT1". Molecular Genetics and Metabolism 105 2 (2012): S27. http://dx.doi.org/10.1016/j.ymgme.2011.11.049.
    Published • 10.1016/j.ymgme.2011.11.049
  15. Ribeiro, Diogo; Duarte, Ana Joana; Amaral, Olga. "Rapid and Cost-Effective Method for the Detection of the c.533G>A Mutation in theHEXAGene". Genetic Testing and Molecular Biomarkers 15 3 (2011): 123-126. http://dx.doi.org/10.1089/gtmb.2010.0129.
    Published • 10.1089/gtmb.2010.0129
  16. Brás-Silva, C.; Monteiro-Sousa, D.; Duarte, A.J.; Guerra, M.; Fontes-Sousa, A.P.; Moura, C.; Areias, J.C.; Leite-Moreira, A.F.. "Nitric oxide and prostaglandins - Important players in endothelin-1 induced myocardial distensibility". Physiological Research 57 2 (2008): 165-174. http://www.scopus.com/inward/record.url?eid=2-s2.0-45849091552&partnerID=MN8TOARS.
  17. Duarte, Ana Joana. "Nitric Oxide and Prostaglandins – important players in the endothelin-1 induced myocardial dystensibility". Physiological Research 57 2 (2007): 165-174. http://www.biomed.cas.cz/physiolres/pdf/57/57_165.pdf.
    Open access • Published
  18. Duarte, Ana Joana. "Evidência funcional para a existência de interacção dos receptores ETA e ETB no coração". Mundo Médico 2007 (2007): 50-54.
    Published
  19. Duarte, Ana Joana. "Urocortina-2, um novo modulador neuro-humoral da função cardíaca.". Mundo Médico 2007 Suplemento (2007): 41-42.
    Accepted
Newsletter article
  1. Duarte, Ana Joana. "O INSA e a resposta de emergência ao diagnóstico laboratorial da COVID-19 em Portugal", Boletim Epidemiológico Observações, 2020, http://repositorio.insa.pt/bitstream/10400.18/7255/1/Boletim_Epidemiologico_Observacoes_NEspecia12-2020_artigo2.pdf.
  2. Duarte, Ana Joana. "Doenças lisossomais de sobrecarga em Portugal: 10 anos de experiência em estudos moleculares no INSA (2006-2016)", Boletim Epidemiológico Observações, 2015, http://repositorio.insa.pt/bitstream/10400.18/3787/1/observacoesNEspecia7-2016_artigo4.pdf.
Thesis / Dissertation
  1. Duarte, Ana Joana. "Estudo de Mosaicismo Cromossómico em casos de Restrição de Crescimento Intra-Uterino por Hibridação Genómica Comparativa". Master, Universidade do Porto Faculdade de Ciências, 2008.
  2. Duarte, Ana Joana. "Mecanismos Neurohumorais e Endoteliais na Insuficiência Cardíaca Diastólica". Degree, Universidade do Porto Faculdade de Ciências, 2006.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/09/20 Modelling Lysosomal Storage Disorders using iPSCs and gene-edited zebrafish Seminários do Departamento de Genética Humana
Instituto Nacional de Saúde Doutor Ricardo Jorge (Porto, Portugal)
2023/06 Generating gene-edited models for Lysosomal Storage Disorders 2th AL4AnimalS Meeting
Universidade de Trás-os-Montes e Alto Douro (Vila Real, Portugal)
2023/05 How to establish stem cell cultures from the dental pulp: a practical guide 2th AL4AnimalS Meeting
Universidade de Trás-os-Montes e Alto Douro (Vila Real, Portugal)
2023/03/31 Gene editing on iPS cells: the first steps IV CECA Meeting
Universidade do Porto (Porto, Portugal)
2023/03 Help comes from unexpected places: How a tiny fairy and a tropical fish may help us model mucopolysccharidoses 19th International Symposium of the Portuguese Society for Metabolic Disorders
Portuguese Society for Metabolic Disorders (Figueira da Foz, Portugal)
2022/11 Use of stem cells to elucidate disease pathology and impacts of substrate Global Symposium on Lysosomal Storage Disorders
(Berlim, Germany)
2022/11 Modelling genetic disorders with an unexpected co-worker: the Tooth Fairy that gifts hope to both children and scientists Modelling genetic disorders with an unexpected co-worker: the Tooth Fairy that gifts hope to both children and scientists. Centro de Investigação Interdisciplinar em Sanidade Animal (CIISA) Congress 2022
Faculdade de Medicina Veterinária - Universidade de Lisboa (Lisboa, Portugal)
2022/06 From fibroblasts to cardiomyocytes and beyond Workshop Sphingolipids in Health and Disease
Aveiro University (Aveiro, Portugal)
2021/10/02 iPSCs como modelos celulares para doenças raras V Jornadas Científicas do CECA
Instituto de Ciências Biomédicas Abel Salazar (PORTO, Portugal)
2021/10/02 RNA como alvo terapêutico: Desenvolvimento de abordagens inovadoras utilizando oligonucleótidos sintéticos V Jornadas Científicas do CECA
Instituto de Ciências Biomédicas Abel Salazar (PORTO, Portugal)
2021/04/29 De célula somática a estaminal e novamente somática: iPSCs como modelos celulares para doenças raras INSA Convida
Instituto Nacional de Saúde Dr. Ricardo Jorge (Portugal)
2020/02/22 Novel tools in cell and molecular biology: induced pluripotent stem cells in the field of lysosomal storage disorders
XII Jornadas de Genética e Biotecnologia / II Jornadas Ibéricas de Genética e Biotecnologia (Portugal)
2018/10/29 Fabry Disease: from iPS cells to Genomic Editing Seminário "À volta da Investigação"
Instituto Nacional de Saúde Dr. Ricardo Jorge (Portugal)
2018/06/14 Inducing Pluripotent Stem Cells in Fibroblasts from Patients with Lysosomal Storage Disorders Seminários do Departamento de Genética Humana
Instituto Nacional de Saúde Dr. Ricardo Jorge (Portugal)
2017/05/08 Splicing therapeutics for patients affected by lysosomal storage disorders 2º Dia do Jovem Investigador do Instituto Nacional de Saúde Doutor Ricardo Jorge
Instituto Nacional de Saúde Doutor Ricardo Jorge (Portugal)
2016/07 Rare diseases - our task: Foreseen accomplishments through precision cellular and molecular biology 14th European Scientific & Training Conference
(Poland)
2016/03/18 Development of RNA based approaches to exploit alternative therapies for lysosomal storage diseases. 12th SPDM symposium
Sociedade Portuguesa de Doenças Metabólicas (Portugal)
2014/03/20 Unverricht-Lundborg disease: development of splicing therapeutic approaches for a patient with an homozygous mutation in the cystatin B gene 10th SPDM International Symposium
Sociedade Portuguesa de Doenças Metabólicas (Portugal)
2010/06/12 Genetic diversity in lysosomal disorders in Portugal Genetics 2010: model organisms to human biology
The Genetics Society of America Conferences (United States)
2007/06/16 Urocortin 2 acutely decreases myocardial stiffness XI Workshop of the ESH Young Investigator Initiative Group
(Italy)
2007/03/21 Efeitos Miocárdicos da Urocortina 2 XXVIII Congresso Português de Cardiologia
(Portugal)
2007/01/24 Nitric oxide and prostaglandins – key downstream modulators of endothelin-1 induced increase in myocardial distensibility Winter Meeting on Translational Basic Science of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) - From Cardiac Adaptation to Failure and Back
(Germany)
2006/09/02 NO and prostaglandins are required for the increase in myocardial distensibility induced by ET-1 XVth World Congress of Cardiology 2006
(Spain)
2006/03/22 O aumento da distensibilidade miocárdica induzido pela endotelina-1 depende da libertação endotelial de NO e prostaglandinas XXVII Congresso Português de Cardiologia
(Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2021/04/01 - 2021/07/15 Estratégia de Investigação da Doença de Fabry
Supervisor
 Genetics and Biotechnology (Degree)
Universidade de Trás-os-Montes e Alto Douro, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2023/02/28 - 2023/02/28 Rare Disease Day 2023 (2023/02/28 - 2023/02/28)
Other (Member of the Organising Committee)
 Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal

Fundação para a Ciência e a Tecnologia, Portugal
2022/02/28 - 2022/02/28 Rare Disease Day 2022 (2022/02/28 - 2022/02/28)
Other (Member of the Organising Committee)
 Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
2022/01/02 - 2022/02/28 Dia das Doenças Raras 2022 - Sensibilizar, Conhecer e Promover a mudança para 6% da população (Rare Disease Day 2022) (2022/02/28 - 2022/02/28)
Congress (Member of the Organising Committee)
 Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal
2018/10/29 - 2018/10/29 Seminário "À volta da Investigação". (2018/10/29 - 2018/10/29)
Conference (Member of the Organising Committee)
 Instituto Nacional de Saúde Doutor Ricardo Jorge - Centro de Saúde Pública Dr. Gonçalves Ferreira, Portugal
Distinctions

Award

2019 Best poster - 13th European Working Group on Gaucher Disease Congress
2016 SPDM award winning presentation 2016. 12th SPDM symposium. March 17-18, Coimbra, Portugal, 2016. Apresentação: "Development of RNA based approaches to exploit alternative therapies for lysosomal storage diseases".
2013 National Award: Genzyme Research Grant / Portuguese Society of Metabolic Diseases 2012
Sociedade Portuguesa de Osteoporose e Doenças Ósseas Metabólicas, Portugal
2013 National Award: Genzyme Research Grant
2007 International Award: Young Investigators Award - Travel Grant of European Society of Hypertension for XVIIth Meeting of European Society of Hypertension, atribuído ao trabalho “Urocortin 2 acutely decreases myocardial stiffness”
2007 International Award: Grant of European Society of Hypertension Young Investigator Initiative Group – 2007, atribuída ao trabalho “Functional evidence for the existence of ETA-ETB receptor crosstalk in the heart”

Other distinction

2007 International Award: Young Investigators Award - Travel Grant of European Society of Hypertension for XVIIth Meeting of European Society of Hypertension, atribuído ao trabalho “Urocortin 2 acutely decreases myocardial stiffness”
2007 International Award: Grant of European Society of Hypertension Young Investigator Initiative Group – 2007, atribuída ao trabalho “Functional evidence for the existence of ETA-ETB receptor crosstalk in the heart”