From August 2002 to 2008 he took part in the bioinformatic group of the University of Aveiro, in which he was involved in several projects of genetic information analysis. One of the developed projects had as its primary goal the study of the primary structure of the mRNA, having produced several scientific studies. He has also developed a neonatal screening system of metabolic diseases in cooperation with the Porto Medical Genetic Institute (IGM), which analyses statistically and stores the information that comes from the mass spectrometer (MS/MS). This system is in its full use, analysing daily 600 newborns and screening approximately 30 disorders in Portugal. NeoScreen is also being used at 3 hospitals in Spain, Porto Rico and Colombia. In 2014, he developed a new version of this software to integrate new statistical functionalities. From 2008 until 2012 he started working in the Bioinformatic unit of Biocant (Cantanhede) developing and improving data analysis pipelines, in the fields of assembly, genome annotation, metagenomic and transcriptomic with data from a 454 sequencer, property of this unit. He had developed a pipeline, in perl, for the annotation of transcriptomics. He also developed a web site for the visualization of information supported in a mySQL database. This pipeline was, successfully, applied in Bathymodiolus azoricus mussel transcriptome, which inhabits deep-sea hydrothermal vents in the Azorean waters, as well as other transcriptomes sequenced by this unit. With this pipeline was possible to analyse several samples sequenced by 454 and conduct to several scientific papers. He also developed a pipeline to metagenomics analysis applied to several projects in Biocant. Several data also produced by 454 was analysed, and again, two scientific papers were published. Several advanced courses were realized in BioCant and he was responsible for the Bioinformatic lectures. Biocant is a Biotechnology Innovation Center that has several facilities which one of them is a sequencing facility (www.biocant.pt) From November of 2012 until July of 2015 he worked in the University of St Andrews, in the Medical department, developing a new bioinformatic unit. We start from scratch, buying servers in first place, configure all the equipment and start presenting the bioinformatic services to the Medical department. Other departments also joined the facility, like Biology and Marine Biology. During this period we have produced three scientific papers and others in submission. From September of 2015 until January of 2018 worked in Ophiomics, a start-up focused in precision medicine having the cancer its target. He has developed all the pipeline of annotation and report generation for germline and somatic panels, analysing the NGS data that are produced by an Ion Proton, owned by Ophiomics. All the data is produced by panels targeting a specific type of cancers. From February of 2018 he started working in iBiMED, in a bioinformatics group. The main duties are to pass the knowledge of several years of experience in next generation sequencing (NGS) to the students and present the right tools/best technological options to get the best answer of the data. From 2012 on he is giving support to the microbiology bioinformatic group of Instituto Nacional de Saúde Doutor Ricardo Jorge (INSA) create/improving algorithms, also developing the INSaFLU (https://insaflu.insa.pt/) a service for surveillance of influenza virus. This project has already produced an article, published in a revised magazine, several participations in congress and present in the guidelines of the European Center for Disease Prevention and Control (ECDC) as an analysis tool for the flu virus. This pipeline is also used in SARS-CoV-2 by INSA. In total, he published 27 papers in ISI indexed journals, including Nature Microbiology (IF=14), Genome Biology (IF=13), Clinical Infectious Diseases (IF=8) and others