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In 2021, I graduated from the University of Algarve with a BSc in Biomedical Sciences. During this program, I completed my final project in Professor José Bragança's lab. The experience sparked my interest in science and led me to pursue a Master of Science (MSc) in Molecular Biology and Microbial Science, which I finished in 2024. For my MSc thesis, I started my research at Professor Inês Araújo's lab, situated at the Algarve Biomedical Center Research Institute (ABC-RI). My project centred on exploring the role of S-nitrosylation of several proteins in aSyn aggregation and toxicity in SH-SY5Y cells. Throughout my research journey, I became proficient in a wide range of techniques, including cell culture, Western blotting, immunofluorescence, confocal microscopy, and cell transfection. During my master’s degree, I undertook a research internship at the same lab for the same project as my thesis. In 2024 I received an award for best oral communication. Throughout the thesis, I organised 5 event(s) and participated in 2 event(s). In October of 2024, I entered the PhD programme in Biomedical Sciences at the Algarve University.
Identification

Personal identification

Full name
Mariana Filipa Fernandes Teixeira

Citation names

  • Teixeira, Mariana

Author identifiers

Ciência ID
4A11-E201-DEA9

Addresses

  • Rua Herculano Saraiva Arquitecto, Número 8, 2°Direito, 7500-110, Vila Nova de Santo André, Setúbal, Portugal (Personal)

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
2024/10/01 - 2027/10/01
Ongoing
Ciências Biomédicas (Doutoramento)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2024/04/11 - 2024/04/11
Concluded
Hands-on workshop, "Quantification in ImageJ". (Outros)
Algarve Biomedical Center Research Institute, Portugal
2021/10/04 - 2024/04/05
Concluded
Molecular Biology and Microbial (Mestrado)
Universidade do Algarve Faculdade de Ciências e Tecnologia, Portugal
"Characterization of the contribution of S-nitrosylated proteins to the aggregation of alpha-synuclein in Parkinson's Disease" (THESIS/DISSERTATION)
16
2024/03/13 - 2024/03/13
Concluded
BioRad - Advance Skills for Western Blotting Sample Preparation (Outros)
Biorad Inc, United States
2023/07/01 - 2023/07/06
Concluded
Brain Organoids Advanced Hands-on Course (Outros)
Centre de Regulació Genòmica, Spain
2022/09/01 - 2022/09/05
Concluded
Hands-on Molecular Biology Tools - a beginners crash course (Outros)
Fundação Champalimaud, Portugal
2018/08/17 - 2021/07/22
Concluded
Ciências Biomédicas (Licenciatura)
Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
"Resgate dos defeitos causados pela diminuição da expressão de CITED2 nas células estaminais embrionárias" (THESIS/DISSERTATION)
14
Affiliation

Science

Category
Host institution
Employer
2024 - Current Researcher (Research) Algarve Biomedical Center Research Institute, Portugal
2023/06/01 - 2024/02/29 Research Trainee (Research) Centro Académico de Investigação e Formação Biomédica do Algarve, Portugal
Algarve Biomedical Center Research Institute, Portugal

Others

Category
Host institution
Employer
2023/01/04 - 2023/01/23 Estágio observacional Centro Hospitalar da Universidade do Algarve, Portugal
2021/01/01 - 2022/01/03 Voluntariado Centro Social Paroquial Santa Maria, Portugal
Casa de Jovens "O Farol", Portugal
2021/10/23 - 2021/11/23 Voluntariado RE-FOOD 4 GOOD-Associação, Portugal
Casa de Jovens "O Farol", Portugal
2018/08/01 - 2020/08/09 Estágio observacional Policlínica de São Jorge, Portugal
2020/07/06 - 2020/08/06 Estágio observacional Clídis, Grupo HPA Saude, clínica de diagnóstico de Sines, Portugal
Casa de Jovens "O Farol", Portugal
2019/10/01 - 2019/12/01 Voluntariado Centro Hospitalar da Universidade do Algarve, Portugal
2018/06/01 - 2018/06/06 Estágio observacional Farmácia Fontes, Portugal
Outputs

Publications

Conference poster
  1. Teixeira, Mariana; Simão, Sónia; Outeiro, Tiago; Araújo, Inês Maria. Corresponding author: Teixeira, Mariana. "Identification of S-nitrosylation targets contributing to pathological aggregation of alpha-synuclein in Parkinson´s disease: a proteomic study". Paper presented in Encontro Ciência 2025, 2025.
  2. Agostinho, Rafaela R.; Teixeira, Mariana; MASCARENHAS MARQUES, VERA; Sofia M. Calado; Bragança, José; Medeiros, Raquel; Martínez-Ruiz, Antonio; Simão, Sónia; Araújo, Inês Maria. Corresponding author: Agostinho, Rafaela R.. ""Optimization of Dimedone Switch Method for detection of S-sulfhydrated proteins in human induced pluripotent stem cells derived from Down syndrome individuals"". Paper presented in 2nd FEBS Redox Medicine Workshop, 2025.
  3. Teixeira, Mariana; Agostinho, Rafaela R.; Martínez-Ruiz, Antonio; Outeiro, Tiago; Araújo, Inês Maria; Simão, Sónia. Corresponding author: Teixeira, Mariana. "Identification of S-nitrosylation targets contributing to pathological aggregation of alfa-synuclein in Parkinson´s Disease: a proteomic study". Paper presented in 2nd FEBS Redox Medicine Workshop, 2025.
Journal article
  1. Simão, Sónia; Santos, Daniela F.; Teixeira, Mariana; Agostinho, Rafaela R.; Rodrigues, Joana; Vitorino, Marta; Araújo, Inês M.. "Unraveling the potential of gasotransmitters as neurogenic and neuroprotective molecules: focus on Alzheimer’s and Parkinson’s diseases". Redox Report 31 1 (2025): https://doi.org/10.1080/13510002.2025.2592413.
    10.1080/13510002.2025.2592413
  2. Simão, Sónia; Teixeira, Mariana; Agostinho, Rafaela; Santos, Daniela F.; Rodrigues, Joana; Vitorino, Marta; Araújo, Inês. Corresponding author: Simão, Sónia. "The role of gasotransmitters in adult neurogenesis (In preparation)". (2024):
  3. Teixeira, Mariana; Simão, Sónia; Agostinho, Rafaela; Outeiro, Tiago; Araújo, Inês. "Characterization of the contribution of S-nitrosylated proteins to the aggregation of alpha-synuclein in Parkinson’s disease (In preparation)". (2024):
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/01/26 Contribuition of S-nitrosylation of PDI to the aggregation and toxicity of alpha-synuclein in SH-SY5Y cells. Teixeira M, Simão S, Agostinho R, Outeiro T, Araújo I. IX Clinical Biochemistry Workshop
Portuguese Society of Biochemistry (Faro, Portugal)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2026/04/09 - 2026/04/27 Validação de proteínas S-nitrosiladas num modelo celular de Doença de Parkinson
Supervisor of Vânia Nobre Rodrigues
Mestrado Integrado em Medicina (Master)
Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
2025/04 - 2025/04 Identificação de alvos de S-nitrosilação que contribuem para a agregação patológica da alfa-sinucleína na doença de Parkinson
Co-supervisor
Mestrado Integrado em Medicina (Master)
Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal

Event organisation

Event name
Type of event (Role)
Institution / Organization
2023/11/23 - 2023/11/23 Semana da Ciência e da Tecnologia: Dinamização de atividade "Como manter o teu cérebro forte?" (2023)
Workshop (Co-organisor)
Centro Ciência Viva do Algarve, Portugal
2023/10/16 - 2023/10/20 Prion (2023)
Congress (Member of the Organising Committee)
Universidade do Algarve - Campus de Gambelas, Portugal
2023/05/03 - 2023/05/05 Fens Regional Meeting, 3rd-5th May 2023, Algarve, Portugal (2023)
Congress (Member of the Organising Committee)
Algarve Biomedical Center Research Institute, Portugal

Federation of European Neuroscience Societies, Belgium
2023/05/02 - 2023/05/02 VII Symposium Portuguese Glial Network - satellite event of FENS and FRM (2023)
Conference (Member of the Organising Committee)
Federation of European Neuroscience Societies, Belgium

Algarve Biomedical Center Research Institute, Portugal
2022/05/22 - 2022/05/22 Visita de estudo UAlg - Sessão experimental: DNA inside cells (2022)
Seminar (Co-organisor)
Algarve Biomedical Center Research Institute, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2026/02/25 - 2026/02/25 Dia Aberto- Universidade do Algarve Dias Abertos - Universidade do Algarve
Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal
2024/04/11 - 2024/04/13 Insight into Parkinson´s: "Parkinson´s Online Conference"
Seminar
Parkinson´s Online Conference
2024/04/04 - 2024/04/04 Palestra, Ansiedade | A visão da Neurociência.
Seminar
Ansiedade | A visão da Neurociência.
Universidade do Minho, Portugal
2024/01/31 - 2024/01/31 How to get Published and Get your Article Accepted in a Good Journal (with Elsevier UK) Workshop
Workshop
How to get Published and Get your Article Accepted in a Good Journal
Centre for Doctoral Studies at King’s College London, United Kingdom
2022/12/06 - 2022/12/07 International Conference, Ageing With]Out[Borders in Faro, Portugal 6-7 December 2022.
Congress
Ageing without Borders
Algarve Biomedical Center Research Institute, Portugal

Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal
2022/10/12 - 2022/10/14 ABC Days - V Annual Meeting of the Algarve Biomedical Center
Congress
ABC Days
Centro Académico de Investigação e Formação Biomédica do Algarve, Portugal

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2025/03/24 - 2025/04/30 Escrita Científica (Curso de doutoramento (conclusão de unidades curriculares)) Escrita Ciêntifica em Ciências da Vida (Outros) Universidade do Algarve Faculdade de Medicina e Ciências Biomédicas, Portugal

Mentoring / Tutoring

Topic Student name
2023/03 - 2023/06 Characterization of the contribution of S-nitrosylation to the aggregation of alpha-synuclein in Parkinson's Disease Catarina Glória
Distinctions

Award

2024 Best Oral Communication Award
Universidade do Algarve - Campus de Gambelas, Portugal