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Identification

Personal identification

Full name
Rui Filipe Duarte da Silva

Citation names

  • Silva, Rui D

Author identifiers

Ciência ID
4616-48C1-AB64
ORCID iD
0000-0003-2168-8599
Google Scholar ID
6YrcX6YAAAAJ&hl
Researcher Id
C-5622-2012
Scopus Author Id
15045741700

Email addresses

  • rfsilva@ualg.pt (Professional)

Addresses

  • Faculty of Medicine and Biomedical Sciences, University of Algarve, Campus de Gambelas, Bld. 2 Lab. 3.64, 8005-139, Faro, Faro, Portugal (Professional)
Education
Degree Classification
2006/03/01 - 2011/07/01
Concluded
 PhD in Biological Sciences (Doutoramento)
Universidade do Minho, Portugal
"Yeast as a model system for the study of Bax regulation by protein kinase C isoforms" (THESIS/DISSERTATION)
Affiliation

Science

Category
Host institution 		Employer
2018/10/24 - 2024/10/23 Contracted Researcher (Research) Universidade do Algarve, Portugal
Universidade do Algarve Algarve Biomedical Center Research Institute, Portugal
2013/03/01 - 2018/10/23 Postdoc (Research) Universidade do Algarve, Portugal
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal

Teaching in Higher Education

Category
Host institution 		Employer
2024/10/24 - Current Invited Assistant Professor (University Teacher) Universidade do Algarve Departamento de Ciências Biomédicas e Medicina, Portugal

Positions / Appointments

Category
Host institution 		Employer
2019/05/01 - Current Head and scientific manager of the Microscopy Facility Universidade do Algarve, Portugal
Outputs

Publications

Conference abstract
  1. Silva, Rui. "Saccharomyces cerevisiae commits to programmed cell death in response to hyperosmotic stress caused by glucose". Paper presented in CYTOMETRY PART A, 2004.
    Published
Journal article
  1. Varland, Sylvia; Silva, Rui D; Kjosås, Ine; Faustino, Alexandra; Bogaert, Annelies; Billmann, Maximilian; Boukhatmi, Hadi; et al. Corresponding author: Silva, Rui D. "N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity". Nature Communications 14 1 (2023): http://dx.doi.org/10.1038/s41467-023-42342-y.
    Open access • Published • 10.1038/s41467-023-42342-y
  2. Carmo, Catarina; Coelho, João; Silva, Rui D; Tavares, Alexandra; Boavida, Ana; Gaetani, Paola; Guilgur, Leonardo G; Martinho, Rui Gonçalo; Oliveira, Raquel A. "A dual-function SNF2 protein drives chromatid resolution and nascent transcript removal in mitosis". EMBO reports 24 9 (2023): http://dx.doi.org/10.15252/embr.202256463.
    10.15252/embr.202256463
  3. Feijão, Tália; Marques, Bruno; Silva, Rui D.; Carvalho, Célia; Sobral, Daniel; Matos, Ricardo; Tan, Tian; et al. "Polycomb group (PcG) proteins prevent the assembly of abnormal synaptonemal complex structures during meiosis". Proceedings of the National Academy of Sciences 119 42 (2022): http://dx.doi.org/10.1073/pnas.2204701119.
    Published • 10.1073/pnas.2204701119
  4. Rathore, Om Singh; Silva, Rui D.; Ascensão-Ferreira, Mariana; Matos, Ricardo; Carvalho, Célia; Marques, Bruno; Tiago, Margarida N.; et al. "NineTeen Complex-subunit Salsa is required for efficient splicing of a subset of introns and dorsal–ventral patterning". RNA 26 12 (2020): 1935-1956. http://dx.doi.org/10.1261/rna.077446.120.
    10.1261/rna.077446.120
  5. Silva, Rui D.; Mirkovic, Mihailo; Guilgur, Leonardo G.; Rathore, Om S.; Martinho, Rui Gonçalo; Oliveira, Raquel A.. "Absence of the Spindle Assembly Checkpoint Restores Mitotic Fidelity upon Loss of Sister Chromatid Cohesion". Current Biology 28 17 (2018): 2837-2844.e3. http://dx.doi.org/10.1016/j.cub.2018.06.062.
    10.1016/j.cub.2018.06.062
  6. Alves, S.; Neiri, L.; Chaves, S.R.; Vieira, S.; Trindade, D.; Manon, S.; Dominguez, V.; et al. "N-terminal acetylation modulates Bax targeting to mitochondria". International Journal of Biochemistry and Cell Biology 95 (2018): 35-42. http://www.scopus.com/inward/record.url?eid=2-s2.0-85038257457&partnerID=MN8TOARS.
    10.1016/j.biocel.2017.12.004
  7. Ribeiro, A.L.; Silva, R.D.; Foyn, H.; Tiago, M.N.; Rathore, O.S.; Arnesen, T.; Martinho, R.G.. "Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion". Scientific Reports 6 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85007014446&partnerID=MN8TOARS.
    10.1038/srep39118
  8. Silva, R.D.; Martinho, R.G.. "Developmental roles of protein N-terminal acetylation". Proteomics 15 14 (2015): 2402-2409. http://www.scopus.com/inward/record.url?eid=2-s2.0-85006355201&partnerID=MN8TOARS.
    10.1002/pmic.201400631
  9. Rodrigues, J.; Silva, R.D.; Noronha, H.; Pedras, A.; Gerós, H.; Côrte-Real, M.. "Flow cytometry as a novel tool for structural and functional characterization of isolated yeast vacuoles". Microbiology (United Kingdom) 159 PART 5 (2013): 848-856. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876924489&partnerID=MN8TOARS.
    10.1099/mic.0.062570-0
  10. Silva, R.D.; Saraiva, L.; Coutinho, I.; Gonçalves, J.; Côrte-Real, M.. "Yeast as a powerful model system for the study of apoptosis regulation by protein kinase C isoforms". Current Pharmaceutical Design 18 17 (2012): 2492-2500. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860467702&partnerID=MN8TOARS.
  11. Vilela-Moura, A.; Schuller, D.; Mendes-Faia, A.; Silva, R.D.; Chaves, S.R.; Sousa, M.J.; Côrte-Real, M.. "The impact of acetate metabolism on yeast fermentative performance and wine quality: Reduction of volatile acidity of grape musts and wines". Applied Microbiology and Biotechnology 89 2 (2011): 271-280. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651067361&partnerID=MN8TOARS.
    10.1007/s00253-010-2898-3
  12. Silva, R.D.; Manon, S.; Gonçalves, J.; Saraiva, L.; Côrte-Real, M.. "Modulation of Bax mitochondrial insertion and induced cell death in yeast by mammalian protein kinase Ca". Experimental Cell Research 317 6 (2011): 781-790. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952191234&partnerID=MN8TOARS.
    10.1016/j.yexcr.2010.12.001
  13. Silva, R.D.; Manon, S.; Gonçalves, J.; Saraiva, L.; Côrte-Real, M.. "The importance of humanized yeast to better understand the role of Bcl-2 family in apoptosis: Finding of novel therapeutic opportunities". Current Pharmaceutical Design 17 3 (2011): 246-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-79958219652&partnerID=MN8TOARS.
    10.2174/138161211795049651
  14. Fontes, N.; Silva, R.; Vignault, C.; Lecourieux, F.; Gerás, H.; Delrot, S.. "Purification and functional characterization of protoplasts and intact vacuoles from grape cells". BMC Research Notes 3 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77949536638&partnerID=MN8TOARS.
    10.1186/1756-0500-3-19
  15. Almeida, T.; Marques, M.; Mojzita, D.; Amorim, M.A.; Silva, R.D.; Almeida, B.; Rodrigues, P.; et al. "Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis". Molecular Biology of the Cell 19 3 (2008): 865-876. http://www.scopus.com/inward/record.url?eid=2-s2.0-41649101223&partnerID=MN8TOARS.
    10.1091/mbc.E07-06-0604
  16. Pereira, C.; Silva, R.D.; Saraiva, L.; Johansson, B.; Sousa, M.J.; Côrte-Real, M.. "Mitochondria-dependent apoptosis in yeast". Biochimica et Biophysica Acta - Molecular Cell Research 1783 7 (2008): 1286-1302. http://www.scopus.com/inward/record.url?eid=2-s2.0-45049085090&partnerID=MN8TOARS.
    10.1016/j.bbamcr.2008.03.010
  17. Saraiva, L.; Silva, R.D.; Pereira, G.; Gonçalves, J.; Côrte-Real, M.. "Specific modulation of apoptosis and Bcl-xL phosphorylation in yeast by distinct mammalian protein kinase C isoforms". Journal of Cell Science 119 15 (2006): 3171-3181. http://www.scopus.com/inward/record.url?eid=2-s2.0-33748290027&partnerID=MN8TOARS.
    10.1242/jcs.03033
  18. Silva, R.D.; Sotoca, R.; Johansson, B.; Ludovico, P.; Sansonetty, F.; Silva, M.T.; Peinado, J.M.; Côrte-Real, M.. "Hyperosmotic stress induces metacaspase- and mitochondria-dependent apoptosis in Saccharomyces cerevisiae". Molecular Microbiology 58 3 (2005): 824-834. http://www.scopus.com/inward/record.url?eid=2-s2.0-27444438569&partnerID=MN8TOARS.
    10.1111/j.1365-2958.2005.04868.x