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Vítor Costa obtained a Biochemistry degree at Universidade do Porto and a PhD in Biomedical Sciences at Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto (ICBAS, UP). He currently holds a position as Associate Professor at ICBAS-UP and leads the Yeast Signalling Networks group at Instituto de Investigação e Inovação em Saúde i3S. Using the yeast Saccharomyces cerevisiae as model organism, his research focuses on the role of bioactive sphingolipids and nutrient signalling in the regulation of organelle function, redox homeostasis, and autophagy, and how deregulation of these signalling networks impacts on aging and cell death in the context of yeast models of human disease, namely Niemann Pick type C and seipinopathy. Vítor Costa co-authored 64 publications with more than 2700 citations (h-index 28) and 3 book chapters, and supervised 6 Post-docs, 9 PhD students and 18 Master students. He is course director of the first degree in Biochemistry (FCUP/ICBAS), member of the scientific committee of the Doctoral Programme in Molecular and Cell Biology (ICBAS/FCUP) and of the Master Degree in Environmental Contamination and Toxicology (ICBAS/FCUP), Academic Editor of Microbial Cell, Review Editor of Frontiers in Cell Death - Cell Death Model Systems, and President of the Portuguese Biochemical Society.
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Identification

Personal identification

Full name
Vítor Manuel Vieira da Costa

Citation names

  • Costa, Vítor

Author identifiers

Ciência ID
3C19-49DF-3ACB
ORCID iD
0000-0002-7868-4663
Researcher Id
A-2647-2008
Scopus Author Id
7103026233; 55303549700

Email addresses

  • vcosta@ibmc.up.pt (Professional)

Telephones

Telephone
  • 226074956 (Professional)
  • 220428134 (Professional)

Addresses

  • Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Professional)
  • ICBAS, Instituto de Ciências Biomédicas Abel Salazar, Departamento de Biologia Molecular, Rua de Jorge Viterbo Ferreira 228, 4050-313, Porto, Porto, Portugal (Professional)

Knowledge fields

  • Natural sciences - Biological Sciences - Biochemistry
  • Natural sciences - Biological Sciences - Molecular Biology

Languages

Language Speaking Reading Writing Listening Peer-review
Portuguese (Mother tongue)
English Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2) Upper intermediate (B2)
Education
Degree Classification
1994/07 - 1998/12
Concluded
 Ciências Biomédicas (Doutoramento)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
"Oxidative stress in Saccharomyces cerevisiae: molecular mechanisms of ethanol and hydrogen peroxide stress responses" (THESIS/DISSERTATION)
1984/10 - 1988/12
Concluded
 Bioquímica (Licenciatura)
Universidade do Porto Faculdade de Ciências, Portugal

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
15
Affiliation

Teaching in Higher Education

Category
Host institution 		Employer
2007/12 - Current Associate Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1998/12 - 2007/12 Assistant Professor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1994/07 - 1998/12 Assistant (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1991/04 - 1994/07 Trainee Assistant (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1988/11 - 1990/08 Tutor (University Teacher) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
Projects

Grant

Designation Funders
2021 - Current PhaseAGE - Excellence Hub on Phase Transitions in Aging and Age-Related Disorders
952334
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
 European Commission
2023/01/01 - 2024/06/30 Comparative analysis of proteomics and genomics of a yeast model of N88S BSCL2/seipin-related human seipinopathy
2022.02305.PTDC
Researcher
Fundação para a Ciência e a Tecnologia
Ongoing
2018/01 - 2019/12 Structure-function studies of neuronal calcium sensor proteins in ceramide signaling using yeast as a model system
441.00 Servia
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2016/05 - 2019/12 Porto Neurosciences and Neurologic Disease Research Initiative at i3S
NORTE-01-0145-FEDER-000008
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Comissao de Coordenacao e Desenvolvimento Regional do Norte
Concluded
2013/06 - 2015/05 Role of the yeast neutral sphingomyelinase in mitochondria function and iron homeostasis.
127248
Provided by PTCRIS: 127248
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2009/01 - 2012/06 Elucidation of ceramide-induced apoptosis: modulation of Protein Kinase C isoforms
Provided by PTCRIS: 69448
69448
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2009/01 - 2011/12 Antioxidant and antiradical characterization of polyphenolic compounds; bioavailability, biological properties and cell signalling.
65501
Provided by PTCRIS: 65501
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2009/01 - 2011/12 Implementation of a Nacional Facility for DNA Microarrays: Phase II
64745
Provided by PTCRIS: 64745
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia, I.P.
Concluded
2005/03 - 2008/02 Oxidative stress and the biology of ageing in Saccharomyces cerevisiae
4.1.3/CAPES/CPLP
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2003/11 - 2007/04 Involvement of sphingolipid signalling in chronological life-span and cell death in Saccharomyces cerevisiae – role of Isc1p sphingomyelinase
POCTI/BCI/45066/2002
Principal investigator
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
2005/09 - 2006/07 Production of new natural dyes and their applications in the food industry
na
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Universidade do Porto
Concluded
2002/07 - 2005/06 Isolation of molecules involved in high-affinity iron uptake systems of Leishmania infantum
POCTI/ESP/41982/2001
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
1999/02 - 2001/01 Oxidative stress: mechanisms involved in the repair of oxidised lipids and proteins in Saccharomyces cerevisiae
PRAXIS/P/BIA/102641/1998
Researcher
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
 Fundação para a Ciência e a Tecnologia
Concluded
1995/01 - 1999/06 Microrganisms in extreme environments: mechanisms of response
PRAXIS XXI/2/2.1/BIO720/94
Researcher
Fundação para a Ciência e a Tecnologia
Concluded
Outputs

Publications

Book chapter
  1. Costa, Vítor; Moradas-Ferreira, Pedro; Rego, Ana Cristina. "Mecanismos moleculares de adaptação ao stresse oxidativo". In Bioquímica – Fundamentos e Correlações Clínicas'. Portugal: Lidel, 2025.
    Accepted
  2. Moradas-Ferreira, Pedro; Barbosa, António Daniel; Costa, Vítor. "O envelhecimento celular". In Biologia Celular e Molecular, edited by Azevedo, Carlos; sunkel, claudio. Portugal: Lidel, 2012.
    Published
  3. Costa, Vítor; Moradas-Ferreira, Pedro. "Mecanismos de adaptação de Saccharomyces cerevisiae a condições de stress". In Biotecnologia - Fundamentos e Aplicações, edited by Lima, Nelson; Mota, Manuel. Portugal: Lidel, 2003.
    Published
Conference abstract
  1. Pereira, Clara; Pereira, Andreia; Pereira, Joana; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Identification of the F1Fo ATP synthase complex ß Subunit as a potential target for the phosphatase Sit4p, impacting on mitochondrial function in yeast". Paper presented in 27th International Conference on Yeast Genetics and Molecular Biology, Yeast, Levico Terme (Trento), 2015.
    Published
  2. Harris, Nicholas; MacLean, Morag; Costa, Vítor; Pedro Moradas-Ferreira; Piper, Peter W.. "Overexpression of superoxide dimutases can extend Saccharomyces cerevisiae chronological life span". Paper presented in The Annual Scientific Meeting of the British Society for Research on Ageing, Mech Ageing Dev, 2002.
    Published
  3. Moradas-Ferreira, Pedro; Costa, Vítor; Amorim, Maria Amélia; Lemos, Maria Albertina; Cruz, Margarida; Quintanilha, Alexandre. "Ethanol stress response in yeast: induction of antioxidant defences". Paper presented in III Congresso Ibérico de Biotecnologia - BIOTEC’96, Valladolid, 1996.
    Published
Conference poster
  1. Ribeiro, Mariana; Oliveira, Mafalda; Nogueira, Verónica; Costa, Vítor; Teixeira, Vitor. "N88S Human Seipinopathy is a lipidopathy associated with loss of iron homeostasis". Paper presented in XXII Congresso Nacional de Bioquímica, 2024.
  2. Correia, Miguel; Martins, Telma; Pinheiro, Denise; Pereira, Clara; Costa, Vítor. "Vps27 is essential for mitochondrial respiration and lifespan extension in Sit4 deficient cells". Paper presented in XXII Congresso Nacional de Bioquímica, 2024.
  3. Martins, Telma; Correia, Miguel; Pinheiro, Denise; Catarina, Lemos; Pereira, Clara; Costa, Vítor. "Vps27 is essential for mitochondrial respiration and lifespan extension in Sit4 deficient cells". Paper presented in 48th FEBS Congress, 2024.
  4. Ribeiro, Mariana; Oliveira, Mafalda; Nogueira, Verónica; Costa, Vítor; Teixeira, Vitor. "Iron dyshomeostasis and disrupted inositol metabolism unveiled: insights from the yeast model of human N88S seipinopathy". Paper presented in 48th FEBS Congress, 2024.
  5. Ribeiro, M.; Nogueira, V.; Costa, Vítor; Teixeira, V.. "Comparative analysis of proteomics and genomics of a yeast model of N88S BSCL2/seipin-related human seipinopathy". Paper presented in IX Workshop de Bioquímica Clínica, 2024.
  6. Nogueira, V.; Costa, Vítor; Teixeira, V.. "Insights from Yeast on Oxidative Stress in N88S seipinopathy". Paper presented in EMBO Workshop “Lipid droplets: Metabolic hubs in health and disease”, 2023.
  7. Martins, T.S.; Correia, M.; Pereira, C.; Costa, Vítor. "Vps27 mediates the mitochondrial derepression and increased lifespan of yeast cells lacking the Sit4 protein phosphatase". Paper presented in 31st International Conference on Yeast Genetics and Molecular Biology, 2023.
  8. Martins, TS; Costa, RS; Lemos, C; Pereira, C; Costa, V. Corresponding author: Costa, V. "Vacuolar membrane proteome and role of amino acids in the lifespan of a Niemann-Pick type C1 yeast model". Paper presented in XXI Congresso Nacional de Bioquímica, 2021.
  9. Martins, TS; Costa, R; Lemos, C; Pereira, C; Costa, V. Corresponding author: Costa, V. "Regulation of the lysosome-like vacuole and amino acid homeostasis in the yeast model of Niemann-Pick type C1". Paper presented in 45th FEBS Congress, 2021.
  10. Pereira, Clara; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "The Sit4p phosphatase controls mitochondrial function and lifespan by regulating the phosphorylation of the ATP synthase beta subunit Atp2p". Paper presented in 19th biennial meeting for the Society for Free Radical Research International, 2018.
  11. Lemos, Vera; Oliveira, Rita M.; Naia, Luana; Szego, Éva; Ramos, Elisabete; Pinho, Sónia; Magro, Fernando; et al. "The NAD-dependent deacetylase SIRT2 reverses hepatic insulin resistance by attenuating ROS generation and mitochondrial dysfunction". Paper presented in MitoPorto – Advances in mitochondrial research, 2017.
  12. Pereira. Clara; Martins, Telma; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Phosphoproteomic screening identifies ATP synthase subunit beta as a target of the yeast type 2A-like protein phosphatase Sit4p". Paper presented in MitoPorto – Advances in mitochondrial research, 2017.
  13. Vilaça, Rita; Barros, Ivo; Matmati, Nabil; Silva, Elísio; Teixeira, Vitor; Hannun, Yusuf A.; Costa, Vítor. "The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics and mitochondrial function in the yeast model of Niemann-Pick type C1". Paper presented in MitoPorto – Advances in mitochondrial research, 2017.
  14. Vilaça, Rita; Barros, Ivo; Matmati, Nabil; Silva, Elísio; Teixeira, Vitor; Hannun, Yusuf A.; Costa, Vítor. "The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in the yeast model of Niemann-Pick type C1". Paper presented in Gordon Research Conference “Lysosomal Diseases”, 2017.
  15. Araújo, Ana R.; Domingues, M.R.; Maciel, M.; Melo, T.; Santinha, D.; Antunes, D.; Morais, C.; et al. "Effects of mistranslation in Saccharomyces cerevisiae: a lipidomics study". Paper presented in XIX Congresso Nacional de Bioquímica, 2016.
  16. Vilaça, Rita; Barros, Ivo; Matmati, Nabil; Silva, Elísio; Teixeira, Vitor; Hannun, Yusuf A.; Costa, Vítor. "The ceramide activated protein phosphatase Sit4p impairs sphingolipid dynamics, mitochondrial function and lifespan in the yeast model of Niemann-Pick type C1". Paper presented in XIX Congresso Nacional de Bioquímica, 2016.
  17. Martins, Telma S.; Pereira, Clara; Teixeira, Vitor; Vilaça, Rita; Moradas-Ferreira, Pedro; Costa, Vítor. "Activation of the transcriptional regulator Aft1p underlies iron accumulation in cells lacking the sphingomyelinase Isc1p". Paper presented in XIX Congresso Nacional de Bioquímica, 2016.
  18. Pereira, Clara; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Identification of the F1Fo ATP synthase ß subunit as a target of the phosphatase Sit4p, impacting mitochondrial function and longevity in yeast". Paper presented in XIX Congresso Nacional de Bioquímica, 2016.
  19. Rego, António; Costa, Vítor; Chaves, Susana R.; Côrte-Real, Manuela. "Ceramide metabolism regulates apoptotic cell death induced by acetic acid via Pkh1p-Ypk1p and Pkh1p-Sch9p pathways". Paper presented in XIX Congresso Nacional de Bioquímica, 2016.
  20. Campos, V; Rego, António; Cunha, R.; Sousa, Maria João; Costa, Vítor; Côrte-Real, Manuela; Chaves, Susana. "Signaling Isc1p-mediated cell death: the role of possible downstream regulators". Paper presented in 11th International Meeting on Yeast Apoptosis, 2015.
  21. Rego, António; Costa, Vítor; Chaves, Susana R.; Côrte-Real, Manuela. "Signaling pathways involved in acetic acid-induced cell death in Saccharomyces cerevisiae". Paper presented in 11th International Meeting on Yeast Apoptosis, 2015.
  22. Martins, Telma S.; Pereira, Clara; Teixeira, Vitor; Leite, A.; Rangel, Maria; Moradas-Ferreira, Pedro; Costa, Vítor. "Role of the sphingomyelinase Isc1p in the regulation of iron homeostasis". Paper presented in 27th International Conference on Yeast Genetics and Molecular Biology, 2015.
  23. Pereira, Clara; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Phosphoproteome analysis to elucidate the role of the ceramide-activated protein phosphatase Sit4p in mitochondrial function and lifespan in yeast". Paper presented in XVIII Congresso Nacional de Bioquímica, 2014.
  24. Teixeira, Vitor; Medeiros, Tânia C.; Vilaça, Rita; Moradas-Ferreira, Pedro; Costa, Vítor. "Ceramide-activated protein phosphatase Sit4p deregulates macroautophagy, mitophagy and mitochondrial dynamics in isc1¿ cells". Paper presented in The FEBS EMBO 2014 Conference, 2014.
  25. Pereira, Clara; Pereira, Andreia; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Identification of the F1Fo ATP synthase complex ß subunit as a potential target for the phosphatase Sit4p, impacting lifespan extension in yeast". Paper presented in 18th European BioEnergetics Conference, 2014.
  26. Mendes, Vanda; Costa, Vítor; Mateus, Nuno. "Involvement of the modulation of cancer cell redox status in the anti-tumoral effect of polyphenols". Paper presented in Oxygen Club of California, 2014.
  27. Pereira, Clara; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Using phosphoproteomics to elucidate the role of the phosphatase Sit4p in mitochondrial function and lifespan yeast". Paper presented in IJUP14-7º Encontro de Investigação Jovem da Universidade do Porto, 2014.
  28. Teixeira, Vitor; Medeiros, Tânia C.; Vilaça, Rita; Moradas-Ferreira, Pedro; Costa, Vítor. "Activation of the protein phosphatase Sit4p impairs macroautophagy, mitophagy and mitochondrial dynamics in isc1¿ cells". Paper presented in Congresso Nacional MicroBiotech13, 2013.
  29. Rego, António; Costa, Margarida; Chaves, Susana R.; Matmati, Nabil; Pereira, Helena; Sousa, Maria João; Moradas-Ferreira, Pedro; et al. "Ceramide metabolism modulates mitochondrial outer membrane permeabilization and apoptosis". Paper presented in 7th International Ceramide Con, 2013.
  30. Teixeira, Vitor; Moradas-Ferreira, Pedro; Costa, Vítor. "TORC1 mediates loss of mitochondrial function in isc1¿ cells". Paper presented in 22nd IUBMB – 37th FEBS Congress, 2012.
  31. Mendes, Vanda; Moradas-Ferreira, Pedro; de Freitas, Vitor; Mateus, Nuno; Costa, Vítor. "Catechol protects yeast cells against hydrogen peroxide stress in Saccharomyces cerevisiae by inducing catalase type T". Paper presented in XXVI International Conference on Polyphenols, 2012.
  32. Bessa, Cláudia; Leão, M.; Gonçalves, Jorge; Côrte-Real, Manuela; Costa, Vítor; Saraiva, Lucília. "Using yeast to study the regulation of mammalian protein kinase c isoforms by the ceramide pathway". Paper presented in XIX Jornadas de Biologia de Levedura “Professor Nicolau van Uden”, 2012.
  33. Vilaça, Rita; Silva, Elísio; Sá-Miranda, Clara; Costa, Vítor. "Deletion of Niemann -Pick type C1 related gene decreases yeast lifespan associated with mitochondrial dysfunctions". Paper presented in Redox signaling and oxidative stress in health and disease, 2012.
  34. Carvalho, Sandra; Silva, Rosa; Shawki, Ali; Mackenzie, Bryan; Castro, Helena; Eide, David; Costa, Vítor; Tomás, Ana M. "Leishmania infantum ZIP3 is a zinc transporter that is tightly regulated by zinc status". Paper presented in Experimental Biology Meeting, 2012.
  35. Barbosa, António Daniel; Graça, João; Mendes, Vanda; Amorim, Maria Amélia; Mendes, Marta Vaz; Moradas-Ferreira, Pedro; Costa, Vítor. "Activation of the Hog1p kinase in Isc1p-deficient yeast cells is associated with mitochondrial dysfunction, oxidative stress sensitivity and premature aging". Paper presented in Congresso Nacional MicroBiotech11, 2011.
    10.1016/j.mad.2012.03.007
  36. Rego, António; Costa, Ana; Chaves, Susana; Moradas-Ferreira, Pedro; Côrte-Real, Manuela; Costa, Vítor. "The involvement of sphingolipids in apoptosis induced by acetic acid in yeast". Paper presented in Congresso Nacional MicroBiotech11, 2011.
  37. Teixeira, Vitor; Moradas-Ferreira, Pedro; Costa, Vítor. "Role of Isc1 in the regulation of unfolded protein response: effect on cell death induced by oxidative stress and ageing in Saccharomyces cerevisiae". Paper presented in Congresso Nacional MicroBiotech11, 2011.
  38. Vilaça, Rita; Balreira, Andrea; Sá-Miranda, Clara; Costa, Vítor. "The Niemann-Pick type C1 protein function is essential for lifespan". Paper presented in VIII International Symposium of Sociedade Portuguesa de Doenças Metabólicas, 2011.
  39. Vilaça, Rita; Gaifém, Joana; Moradas-Ferreira, Pedro; Sá-Miranda, Clara; Costa, Vítor. "The Niemann-Pick type C1 protein plays a key role in redox homeostasis and lifespan". Paper presented in 18th workshop of the European Study Group on Lysosomal Diseases, 2011.
  40. Vilaça, Rita; Sá-Miranda, Clara; Moradas-Ferreira, Pedro; Costa, Vítor. "Unraveling the molecular aspects of Niemann-Pick type C". Paper presented in XVII Congresso Nacional de Bioquímica, 2010.
  41. Rego, António; Costa, Ana Margarida; Chaves, Susana; Moradas-Ferreira, Pedro; Côrte-Real, Manuela; Costa, Vítor. "Role of ceramide pathway in apoptotic signalling induced by acetic acid in yeast". Paper presented in XVII Congresso Nacional de Bioquímica, 2010.
  42. Mendes, Vanda; Moradas-Ferreira, Pedro; de Freitas, Vitor; Mateus, Nuno; Costa, Vítor. "Oxidative stress protection in S. cerevisiae by myricetin, pyrogallol and phloroglucinol". Paper presented in XVII Congresso Nacional de Bioquímica, 2010.
  43. Rego, António; Costa, Ana Margarida; Moradas-Ferreira, Pedro; Côrte-Real, Manuela; Costa, Vítor. "Role of ceramide pathway in apoptotic signalling induced by acetic acid in yeast". Paper presented in XXXV Jornadas Portuguesas de Genética, 2010.
  44. Barbosa, António Daniel; Amorim, Maria Amélia; Moradas-Ferreira, Pedro; Costa, Vítor. "Isc1-dependent regulation of the cell integrity pathway is required for oxidative stress resistance and chronological lifespan in yeast". Paper presented in XXXV Jornadas Portuguesas de Genética, 2010.
  45. Barbosa, António Daniel; Osório, Hugo; Alves, Mariana; Amorim, Maria Amélia; Moradas-Ferreira, Pedro; Costa, Vítor. "ISC1-dependent regulation of the cell integrity pathway is required for oxidative stress resistance and chronological lifespan in yeast". Paper presented in Annual meeting of the Coordination Action LINK-AGE - Third topic research groups meeting, 2009.
  46. Vilaça, Rita; Azevedo, J.; Gonçalves, R.; Amorim, Maria Amélia; Mendes, Vanda; Moradas-Ferreira, Pedro; de Freitas, Vitor; Mateus, Nuno; Costa, Vítor. "Protective effect of pomegranate juice against oxidative stress in Saccharomyces cerevisiae". Paper presented in 24th International Conference on Yeast Genetics and Molecular Biology, 2009.
  47. Barbosa, António Daniel; Osório, Hugo; Alves, Mariana; Amorim, Maria Amélia; Moradas-Ferreira, Pedro; Costa, Vítor. "The role of Sit4 in Isc1-dependent sphingolipid signalling during oxidative stress and chronological ageing in yeast". Paper presented in 24th International Conference on Yeast Genetics and Molecular Biology, 2009.
  48. Barbosa, António Daniel; Osório, Hugo; Alves, Mariana; Amorim, Maria Amélia; Moradas-Ferreira, Pedro; Costa, Vítor. "Chronological ageing and oxidative stress in Saccharomyces cerevisiae: the role of Sit4 in Isc1-dependent sphingolipid signalling". Paper presented in MARK-AGE/LINK-AGE joint summer school "From molecular mechanisms to biomarkers of human ageing", 2009.
  49. Barbosa, António Daniel; Osório, Hugo; Alves, Mariana; Amorim, Maria Amélia; Moradas-Ferreira, Pedro; Costa, Vítor. "ISC1-dependent sphingolipid signalling during oxidative stress and chronological ageing in yeast". Paper presented in XVI Congresso Nacional de Bioquímica, 2008.
  50. Vilaça, Rita; Amorim, Maria Amélia; Moradas-Ferreira, Pedro; de Freitas, Vitor; Costa, Vítor; Mateus, Nuno. "Downregulation of the AMPK protein kinase Snf1p increases cellular protection by quercetin against oxidative stress in yeast". Paper presented in XXIVth International Conference on Polyphenols, 2008.
  51. Mannarino, S.C.; Amorim, Maria Amélia; Pereira, M.D.; Panek, A.D.; Moradas-Ferreira, Pedro; Costa, Vítor; Eleutherio, E.C.A.. "Glutathione is necessary to ensure benefits of calorie restriction during ageing in S. cerevisiae". Paper presented in 37th Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology, 2008.
  52. Almeida, Teresa; Amorim, Maria Amélia; Almeida, Bruno; Figueiredo, Elisabete; LUDOVICO, PAULA; Moradas-Ferreira, Pedro; Côrte-Real, Manuela; Costa, Vítor. "Role of Lcb5p in oxidative stress resistance and ageing in yeast". Paper presented in LINK-AGE Meeting and IBMC Symposium “The free radical theory of ageing – 50 years and beyond: a tribute to Denham Harman”, 2007.
  53. Mannarino, S.C.; Pereira, M.D.; Panek, A.D.; Moradas-Ferreira, Pedro; Costa, Vítor; Eleutherio, E.C.A.. "Superoxide dismutase activation during oxidative stress in S. cerevisiae requires glutathione". Paper presented in 10th IUBMB Conference & 36th Annual Meeting of the Brazilian Society for Biochemistry and Molecular Biology, 2007.
  54. Almeida, Teresa; Marques, Marta; Mojzita, Dominik; Rodrigues, Pedro; Amorim, Maria Amélia; LUDOVICO, PAULA; Hohmann, Stefan; et al. "Role of Isc1 in oxidative stress resistance and ageing in yeast". Paper presented in 47th International Conference on the Bioscience of Lipids, 2006.
  55. Almeida, Teresa; Marques, Marta; Amorim, Maria Amélia; LUDOVICO, PAULA; Moradas-Ferreira, Pedro; Côrte-Real, Manuela; Costa, Vítor. "Yeast neutral sphingomyelinase Isc1p: role in cell death associated with oxidative stress and ageing". Paper presented in 2nd International Congress on Stress Responses in Biology and Medicine, 2005.
  56. Almeida, Teresa; Marques, Marta; Amorim, Maria Amélia; LUDOVICO, PAULA; Moradas-Ferreira, Pedro; Côrte-Real, Manuela; Costa, Vítor. "The role of the yeast neutral sphingomyelinase Isc1p in cell death associated with oxidative stress and ageing". Paper presented in 2nd Spanish and Portuguese Congress on Free Radicals, 2004.
  57. Mateus, Nuno; Faria, A.; Ventura, S.; Costa, Vítor; Moradas-Ferreira, Pedro; de Freitas, Vitor. "Protective effect of polyphenols on yeast life span and oxidative stress resistance". Paper presented in XXII International Conference on Polyphenols, 2004.
  58. Almeida, Teresa; Marques, Marta; Amorim, Maria Amélia; LUDOVICO, PAULA; Moradas-Ferreira, Pedro; Côrte-Real, Manuela; Costa, Vítor. "Sphingolipid signalling in stress resistance and chronological life-span in Saccharomyces cerevisiae: the role of Isc1p". Paper presented in XXI International Conference on Yeast Genetics and Molecular Biology, 2003.
  59. Marques, Marta; Costa, Vítor; Mojzita, Dominik; Amorim, Maria Amélia; Almeida, Teresa; Hohmann, Stefan; Moradas-Ferreira, Pedro. "Transcriptional response during recovery of Saccharomyces cerevisiae cells from hydrogen peroxide stress". Paper presented in XXI International Conference on Yeast Genetics and Molecular Biology, 2003.
  60. Marques, Marta; Costa, Vítor; Amorim, Maria Amélia; Moradas-Ferreira, Pedro. "Recovery of Saccharomyces cerevisiae cells from hydrogen peroxide stress – turnover and re-activation of glyceraldehyde-3-phosphate dehydrogenase". Paper presented in XI Biennial Meeting of the Society for Free Radical Research International, 2002.
  61. Marques, Marta; Costa, Vítor; Amorim, Maria Amélia; Moradas-Ferreira, Pedro. "Hydrogen peroxide stress in Saccharomyces cerevisiae cells - cell recovery is linked to glucose metabolism". Paper presented in 2nd International Meeting on Cellular Responses to Oxidative and Osmotic Stress, 2001.
  62. Marques, Marta; Costa, Vítor; Amorim, Maria Amélia; Moradas-Ferreira, Pedro. "Recovery of Saccharomyces cerevisiae cells from oxidative stress by hydrogen peroxide stress - glucose metabolism and proteolytic activity". Paper presented in FEBS Meeting, 2001.
  63. Marques, Marta; Costa, Vítor; Amorim, Maria Amélia; Moradas-Ferreira, Pedro. "Mechanisms involved in the recovery of Saccharomyces cerevisiae cells from oxidative stress by hydrogen peroxide". Paper presented in 10th International Symposium on Yeasts, 2000.
  64. Marques, Marta; Costa, Vítor; Amorim, Maria Amélia; Moradas-Ferreira, Pedro. "Glucose metabolism and turnover of oxidised proteins during the recovery of yeast cells from hydrogen peroxide stress". Paper presented in 18th International Congress of Biochemistry and Molecular Biology, 2000.
  65. Costa, Vítor; Marques, Marta; Amorim, Maria Amélia; Moradas-Ferreira, Pedro. "Protein oxidation by hydrogen peroxide in Saccharomyces cerevisiae". Paper presented in International Congress on Cellular Responses to Oxidative and Osmotic Stress, 1999.
  66. Santos, Manuel; Cheesman, C.; Costa, Vítor; Moradas-Ferreira, Pedro; Tuite, M.F.. "Gene expression re-programming by genetic code ambiguity in Saccharomyces cerevisiae". Paper presented in XI Congresso Nacional de Bioquímica, 1998.
  67. Costa, Vítor; Amorim, Maria Amélia; Quintanilha, Alexandre; Moradas-Ferreira, Pedro. "Oxidative damages in Saccharomyces cerevisiae". Paper presented in IX Biennial Meeting, International Society for Free Radical Research, 1998.
  68. Mateus, Nuno; Costa, Vítor; Santos, Manuel; Moradas-Ferreira, Pedro. "Antioxidant defences in Saccharomyces cerevisiae transformed with Candida albicans tRNAcag - a positive selection mechanism?". Paper presented in 3º Congresso de Radicais Livres em Química, Biologia e Medicina, 1997.
  69. Costa, Vítor; Amorim, Maria Amélia; Rodrigues-Pousada, Claudina; Quintanilha, Alexandre; Moradas-Ferreira, Pedro. "Molecular damages induced by stress in Saccharomyces cerevisiae". Paper presented in Euroconference “Microbial Response to Stress: what's new and how can it be applied?, 1997.
  70. Costa, Vítor; Fernandes, Lisete; Rodrigues-Pousada, Claudina; Moradas-Ferreira, Pedro. "The role of YAP2 transcription factor on the resistance of Saccharomyces cerevisiae to hydrogen peroxide". Paper presented in X Congresso Nacional de Bioquímica, 1996.
  71. Costa, Vítor; Amorim, Maria Amélia; Quintanilha, Alexandre; Moradas-Ferreira, Pedro. "The role of mitochondrial superoxide dismutase on ethanol tolerance of stationary phase S. cerevisiae cells". Paper presented in 4th IUBMB Conference “The life and death of the cell”, 1996.
  72. Costa, Vítor; Amorim, Maria Amélia; Quintanilha, Alexandre; Moradas-Ferreira, Pedro. "Antioxidant defenses in the stationary phase of S. cerevisiae - correlation with ethanol resistance". Paper presented in 2º Congresso de Radicais Livres em Química, Biologia e Medicina, 1995.
  73. Costa, Vítor; Fernandes, Lisete; Teixeira, Alexandra; Moradas-Ferreira, Pedro; Rodrigues-Pousada, Claudina. "Effect of YAP2 on Saccharomyces cerevisiae superoxide dismutase in the presence of hydrogen peroxide". Paper presented in 17th International Conference on Yeast Genetics and Molecular Biology, 1995.
  74. Costa, Vítor; Reis, Eduardo; Quintanilha, Alexandre; Moradas-Ferreira, Pedro. "Ethanol toxicity in Saccharomyces cerevisiae is correlated with reactive oxygen species". Paper presented in 16th International Specialized Symposium on Yeast, 1993.
  75. Costa, Vítor; Reis, Eduardo; Quintanilha, Alexandre; Moradas-Ferreira, Pedro. "Stress effect on antioxidant defenses". Paper presented in 21th FEBS Meeting, 1992.
  76. Costa, Vítor; Quintanilha, Alexandre; Moradas-Ferreira, Pedro. "Superoxide dismutase activity in ethanol-tolerant Saccharomyces cerevisiae cells". Paper presented in 1º Congresso Nacional sobre radicais livres de oxigénio, 1991.
  77. Costa, Vítor; Quintanilha, Alexandre; Moradas-Ferreira, Pedro. "Ethanol stress and antioxidant defenses in yeast". Paper presented in IV Portuguese-Spanish Biochemistry Congress, 1991.
  78. Moradas-Ferreira, Pedro; Amorim, Maria Amélia; Lemos, Maria Albertina; Costa, Vítor; Mager, W.. "Effect of ethanol on mRNA and protein synthesis in Saccharomyces cerevisiae". Paper presented in Cold Spring Harbor Laboratory Meeting: “Stress proteins and the heat shock response”, 1991.
  79. Amorim, Maria Amélia; Lemos, Maria Albertina; Costa, Vítor; Moradas-Ferreira, Pedro. "Ethanol stress proteins in Saccharomyces cerevisiae”". Paper presented in Lunteren Lectures on Molecular Genetics: “The stress response in microorganisms”, 1990.
  80. Moradas-Ferreira, Pedro; Costa, Vítor; Guerreiro, P.; Rodrigues-Pousada, Claudina. "Thermotolerance in Tetrahymena pyriformis: correlation between thermic stress and oxidative stress". Paper presented in 19th FEBS Meeting, 1989.
Journal article
  1. Ribeiro, Mariana O.; Oliveira, Mafalda; Nogueira, Verónica; Costa, Vítor; Teixeira, Vitor. "N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis". Cell Communication and Signaling 23 1 (2025): https://doi.org/10.1186/s12964-024-02007-9.
    Published • 10.1186/s12964-024-02007-9
  2. Martins, Telma S.; Correia, Miguel; Pinheiro, Denise; Lemos, Carolina; Mendes, Marta Vaz; Pereira, Clara; Costa, Vítor. "Sit4 Genetically Interacts with Vps27 to Regulate Mitochondrial Function and Lifespan in Saccharomyces cerevisiae". Cells 13 8 (2024): 655. http://dx.doi.org/10.3390/cells13080655.
    Published • 10.3390/cells13080655
  3. Sousa, André D.; Costa, Ana Luisa; Costa, Vítor; Pereira, Clara. "Prediction and biological analysis of yeast VDAC1 phosphorylation". Archives of Biochemistry and Biophysics 753 (2024): 109914. http://dx.doi.org/10.1016/j.abb.2024.109914.
    Published • 10.1016/j.abb.2024.109914
  4. Leite, Ana Cláudia; Costa, Vítor; Pereira, Clara. "Mitochondria and the cell cycle in budding yeast". The International Journal of Biochemistry and Cell Biology 161 (2023): 106444. http://dx.doi.org/10.1016/j.biocel.2023.106444.
    Published • 10.1016/j.biocel.2023.106444
  5. Martins, Telma S.; Costa, Rafaela S.; Vilaça, Rita; Lemos, Carolina; Teixeira, Vitor; Pereira, Clara; Costa, Vítor; et al. Corresponding author: Costa, Vítor. "Iron Limitation Restores Autophagy and Increases Lifespan in the Yeast Model of Niemann-Pick Type C1". International Journal of Molecular Sciences 24 6221 (2023): https://doi.org/10.3390/ijms24076221.
    Open access • Published • 10.3390/ijms24076221
  6. Ana Cláudia Leite; Maria Barbedo; Vítor Costa; Clara Pereira. "The APC/C Activator Cdh1p Plays a Role in Mitochondrial Metabolic Remodelling in Yeast". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24044111.
    10.3390/ijms24044111
  7. Ana Cláudia Leite; Telma S. Martins; Rute R. Cesário; Vitor Teixeira; Vítor Costa; Clara Pereira. "Mitochondrial respiration promotes Cdc37-dependent stability of the Cdk1 homolog Cdc28". Journal of Cell Science (2023): https://doi.org/10.1242/jcs.260279.
    10.1242/jcs.260279
  8. Costa, Vítor; Teixeira, Vitor. "Oxidative stress in N88S seipinopathy: novel insights into the mechanisms of neurodegeneration and therapeutic avenues". Neural Regeneration Research 18 8 (2023): 0. http://dx.doi.org/10.4103/1673-5374.363196.
    10.4103/1673-5374.363196
  9. Nogueira, Verónica; Chang, Che-Kang; Lan, Chung-Yu; Pereira, Clara; Costa, Vítor; Teixeira, Vitor. "Causative links between ER stress and oxidative damage in a yeast model of human N88S seipinopathy". Free Radical Biology and Medicine 192 (2022): 165-181. http://dx.doi.org/10.1016/j.freeradbiomed.2022.09.009.
    10.1016/j.freeradbiomed.2022.09.009
  10. Leite, Ana Cláudia; Martins, Telma Silva; Campos, Ana; Costa, Vítor; Pereira, Clara. "Phosphoregulation of the ATP synthase beta subunit stimulates mitochondrial activity for G2/M progression". Advances in Biological Regulation 85 (2022): 100905. http://dx.doi.org/10.1016/j.jbior.2022.100905.
    10.1016/j.jbior.2022.100905
  11. Rakotonirina-Ricquebourg, R.; Costa, Vítor; Teixeira, Vitor. "Hello from the other side: Membrane contact of lipid droplets with other organelles and subsequent functional implications". Progress in Lipid Research 85 (2022): 101141-101141. http://dx.doi.org/10.1016/j.plipres.2021.101141.
    10.1016/j.plipres.2021.101141
  12. Vitor Teixeira; Telma S. Martins; William A. Prinz; Vítor Costa. "Target of Rapamycin Complex 1 (TORC1), Protein Kinase A (PKA) and Cytosolic pH Regulate a Transcriptional Circuit for Lipid Droplet Formation". International Journal of Molecular Sciences (2021): https://www.mdpi.com/1422-0067/22/16/9017.
    10.3390/ijms22169017
  13. Teixeira, Vitor; Maciel, Patrícia; Costa, Vítor. "Leading the way in the nervous system: Lipid Droplets as new players in health and disease". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1866 1 (2021): 158820. http://dx.doi.org/10.1016/j.bbalip.2020.158820.
    10.1016/j.bbalip.2020.158820
  14. António Rego; Filipa Mendes; Vítor Costa; Susana Rodrigues Chaves; Manuela Côrte-Real. "Pkh1p-Ypk1p and Pkh1p-Sch9p Pathways Are Activated by Acetic Acid to Induce a Mitochondrial-Dependent Regulated Cell Death". Oxidative Medicine and Cellular Longevity (2020): https://doi.org/10.1155/2020/7095078.
    10.1155/2020/7095078
  15. Pereira, Clara; Pereira, Andreia T.; Costa, Vítor. "Activation of SNF1/AMPK mediates the mitochondrial derepression, resistance to oxidative stress and increased lifespan of cells lacking the phosphatase Sit4p". Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1867 4 (2020): 118660. http://dx.doi.org/10.1016/j.bbamcr.2020.118660.
    Published • 10.1016/j.bbamcr.2020.118660
  16. Lobo-da-Cunha, Alexandre; Amaral-de-Carvalho, Diogo; Calado, Gonçalo; Costa, Vítor. "Oxidation of cinnamyl alcohol and ethanol by oxidases and dehydrogenases in the digestive gland of gastropods". Journal of Molluscan Studies 85 4 (2019): 397-402. http://dx.doi.org/10.1093/mollus/eyz025.
    10.1093/mollus/eyz025
  17. Araújo, Ana Rita D.; Melo, Tânia; Maciel, Elisabete A.; Pereira, Clara; Morais, Catarina M.; Santinha, Deolinda R.; Tavares, Joana F.; et al. "Errors in protein synthesis increase the level of saturated fatty acids and affect the overall lipid profiles of yeast". PLOS ONE 13 8 (2018): e0202402. http://dx.doi.org/10.1371/journal.pone.0202402.
    Published • 10.1371/journal.pone.0202402
  18. Martins, Telma S.; Costa, Vítor; Pereira, Clara. "Signaling pathways governing iron homeostasis in budding yeast". Molecular Microbiology 109 4 (2018): 422-432. http://dx.doi.org/10.1111/mmi.14009.
    10.1111/mmi.14009
  19. Pereira, Clara; Pereira, Andreia T.; Osório, Hugo; Moradas-Ferreira, Pedro; Costa, Vítor. "Sit4p-mediated dephosphorylation of Atp2p regulates ATP synthase activity and mitochondrial function". Biochimica et Biophysica Acta (BBA) - Bioenergetics 1859 8 (2018): 591-601. http://dx.doi.org/10.1016/j.bbabio.2018.04.011.
    10.1016/j.bbabio.2018.04.011
  20. Rego, António; Cooper, Katrina F.; Snider, Justin; Hannun, Yusuf A.; Costa, Vítor; Côrte-Real, Manuela; Chaves, Susana R.. "Acetic acid induces Sch9p-dependent translocation of Isc1p from the endoplasmic reticulum into mitochondria". Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1863 6 (2018): 576-583. http://dx.doi.org/10.1016/j.bbalip.2018.02.008.
    10.1016/j.bbalip.2018.02.008
  21. Lobo-da-Cunha, Alexandre; Amaral-de-Carvalho, Diogo; Oliveira, Elsa; Alves, Ângela; Costa, Vítor; Calado, Gonçalo. "Mannitol oxidase and polyol dehydrogenases in the digestive gland of gastropods: Correlations with phylogeny and diet". PLOS ONE 13 3 (2018): e0193078. http://dx.doi.org/10.1371/journal.pone.0193078.
    10.1371/journal.pone.0193078
  22. Carmona-Gutierrez, Didac; Bauer, Maria Anna; Zimmermann, Andreas; Aguilera, Andrés; Austriaco, Nicanor; Ayscough, Kathryn; Balzan, Rena; et al. "Guidelines and recommendations on yeast cell death nomenclature". Microbial Cell 5 1 (2018): 4-31. http://dx.doi.org/10.15698/mic2018.01.607.
    10.15698/mic2018.01.607
  23. Vilaça, R.; Barros, I.; Matmati, N.; Silva, E.; Martins, T.; Teixeira, V.; Hannun, Y.A.; Costa, V.. "The ceramide activated protein phosphatase Sit4 impairs sphingolipid dynamics, mitochondrial function and lifespan in a yeast model of Niemann-Pick type C1". Biochimica et Biophysica Acta - Molecular Basis of Disease 1864 1 (2018): 79-88. http://www.scopus.com/inward/record.url?eid=2-s2.0-85031804747&partnerID=MN8TOARS.
    10.1016/j.bbadis.2017.10.010
  24. Martins, T.S.; Pereira, C.; Canadell, D.; Vilaça, R.; Teixeira, V.; Moradas-Ferreira, P.; de Nadal, E.; Posas, F.; Costa, V.. "The Hog1p kinase regulates Aft1p transcription factor to control iron accumulation". Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1863 1 (2018): 61-70. http://www.scopus.com/inward/record.url?eid=2-s2.0-85032229876&partnerID=MN8TOARS.
    10.1016/j.bbalip.2017.10.001
  25. Oliveira, A.V.; Vilaça, R.; Santos, C.N.; Costa, V.; Menezes, R.. "Exploring the power of yeast to model aging and age-related neurodegenerative disorders". Biogerontology 18 1 (2017): 3-34. http://www.scopus.com/inward/record.url?eid=2-s2.0-84994079430&partnerID=MN8TOARS.
    10.1007/s10522-016-9666-4
  26. Lemos, V.; de Oliveira, R.M.; Naia, L.; Szegö, E.; Ramos, E.; Pinho, S.; Magro, F.; et al. "The NAD+-dependent deacetylase SIRT2 attenuates oxidative stress and mitochondrial dysfunction and improves insulin sensitivity in hepatocytes". Human Molecular Genetics 26 21 (2017): 4105-4117. http://www.scopus.com/inward/record.url?eid=2-s2.0-85034211658&partnerID=MN8TOARS.
    10.1093/hmg/ddx298
  27. Carvalho, N.; Coelho, E.; Gales, L.; Costa, V.; Teixeira, J.A.; Moradas-Ferreira, P.. "Production of orotic acid by a Klura3d mutant of Kluyveromyces lactis". Journal of Bioscience and Bioengineering 121 6 (2016): 625-630. http://www.scopus.com/inward/record.url?eid=2-s2.0-84950152580&partnerID=MN8TOARS.
    10.1016/j.jbiosc.2015.10.008
  28. Barbosa, A.D.; Pereira, C.; Osório, H.; Moradas-Ferreira, P.; Costa, V.. "The ceramide-activated protein phosphatase Sit4p controls lifespan, mitochondrial function and cell cycle progression by regulating hexokinase 2 phosphorylation". Cell Cycle 15 12 (2016): 1620-1630. http://www.scopus.com/inward/record.url?eid=2-s2.0-84973144139&partnerID=MN8TOARS.
    10.1080/15384101.2016.1183846
  29. Teixeira, V.; Medeiros, T.C.; Vilaça, R.; Ferreira, J.; Moradas-Ferreira, P.; Costa, V.. "Ceramide signaling targets the PP2A-like protein phosphatase Sit4p to impair vacuolar function, vesicular trafficking and autophagy in Isc1p deficient cells". Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids 1861 1 (2016): 21-33. http://www.scopus.com/inward/record.url?eid=2-s2.0-84944937082&partnerID=MN8TOARS.
    10.1016/j.bbalip.2015.10.004
  30. Teixeira, V.; Costa, V.. "Unraveling the role of the Target of Rapamycin signaling in sphingolipid metabolism". Progress in Lipid Research 61 (2016): 109-133. http://www.scopus.com/inward/record.url?eid=2-s2.0-84952328556&partnerID=MN8TOARS.
    10.1016/j.plipres.2015.11.001
  31. Mendes, V.; Vilaça, R.; De Freitas, V.; Ferreira, P.M.; Mateus, N.; Costa, V.. "Effect of myricetin, pyrogallol, and phloroglucinol on yeast resistance to oxidative stress". Oxidative Medicine and Cellular Longevity 2015 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84929376545&partnerID=MN8TOARS.
    10.1155/2015/782504
  32. Pereira, C.; Costa, V.; Martins, L.M.; Saraiva, L.. "A yeast model of the Parkinson's disease-associated protein Parkin". Experimental Cell Research 333 1 (2015): 73-79. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926408656&partnerID=MN8TOARS.
    10.1016/j.yexcr.2015.02.018
  33. Teixeira, V.; Medeiros, T.C.; Vilaça, R.; Pereira, A.T.; Chaves, S.R.; Côrte-Real, M.; Moradas-Ferreira, P.; Costa, V.. "Ceramide signalling impinges on Sit4p and Hog1p to promote mitochondrial fission and mitophagy in Isc1p-deficient cells". Cellular Signalling 27 9 (2015): 1840-1849. http://www.scopus.com/inward/record.url?eid=2-s2.0-84935020105&partnerID=MN8TOARS.
    10.1016/j.cellsig.2015.06.001
  34. Carvalho, S.; Barreira da Silva, R.; Shawki, A.; Castro, H.; Lamy, M.; Eide, D.; Costa, V.; Mackenzie, B.; Tomás, A.M.. "LiZIP3 is a cellular zinc transporter that mediates the tightly regulated import of zinc in Leishmania infantum parasites". Molecular Microbiology 96 3 (2015): 581-595. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928391014&partnerID=MN8TOARS.
    10.1111/mmi.12957
  35. Vitor Teixeira; Instituto de Biologia Molecular e Celular; Rua do Campo Alegre; 823; 4150-180 Porto; Portugal; Tania Medeiros; et al. "Reduced TORC1 signaling abolishes mitochondrial dysfunctions and shortened chronological lifespan of Isc1p-deficient cells". Microbial Cell (2014):
    10.15698/mic2014.01.121
  36. Vilaça, R.; Silva, E.; Nadais, A.; Teixeira, V.; Matmati, N.; Gaifem, J.; Hannun, Y.A.; Sá Miranda, M.C.; Costa, V.. "Sphingolipid signalling mediates mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1". Molecular Microbiology 91 3 (2014): 438-451. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908101723&partnerID=MN8TOARS.
    10.1111/mmi.12470
  37. Rego, A.; Trindade, D.; Chaves, S.R.; Manon, S.; Costa, V.; Sousa, M.J.; Côrte-Real, M.. "The yeast model system as a tool towards the understanding of apoptosis regulation by sphingolipids". FEMS Yeast Research 14 1 (2014): 160-178. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893817418&partnerID=MN8TOARS.
    10.1111/1567-1364.12096
  38. Mendes, V.; Costa, V.; Mateus, N.. "Involvement of the modulation of cancer cell redox status in the anti-tumoral effect of phenolic compounds". RSC Advances 5 1 (2014): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84915813013&partnerID=MN8TOARS.
    10.1039/c4ra10590g
  39. Ramos, M.A.; Sousa, N.R.; Franco, A.R.; Costa, V.; Oliveira, R.S.; Castro, P.M.L.. "Effect of diflubenzuron on the development of Pinus pinaster seedlings inoculated with the ectomycorrhizal fungus Pisolithus tinctorius". Environmental Science and Pollution Research 20 1 (2013): 582-590. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871967893&partnerID=MN8TOARS.
    10.1007/s11356-012-1056-0
  40. Bessa, C.; Pereira, C.; Leão, M.; Maciel, C.; Gomes, S.; Gonçalves, J.; Corte-Real, M.; Costa, V.; Saraiva, L.. "Using yeast to uncover the regulation of protein kinase Cd by ceramide". FEMS Yeast Research 13 7 (2013): 700-705. http://www.scopus.com/inward/record.url?eid=2-s2.0-84886089759&partnerID=MN8TOARS.
    10.1111/1567-1364.12069
  41. Ludovico, P.; Osiewacz, H.D.; Costa, V.; Burhans, W.C.. "Cellular models of aging". Oxidative Medicine and Cellular Longevity (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84872777147&partnerID=MN8TOARS.
    10.1155/2012/616128
  42. Rego, A.; Costa, M.; Chaves, S.R.; Matmati, N.; Pereira, H.; Sousa, M.J.; Moradas-Ferreira, P.; et al. "Modulation of Mitochondrial Outer Membrane Permeabilization and Apoptosis by Ceramide Metabolism". PLoS ONE 7 11 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84870718175&partnerID=MN8TOARS.
    10.1371/journal.pone.0048571
  43. Barbosa, A.D.; Graça, J.; Mendes, V.; Chaves, S.R.; Amorim, M.A.; Mendes, M.V.; Moradas-Ferreira, P.; Côrte-Real, M.; Costa, V.. "Activation of the Hog1p kinase in Isc1p-deficient yeast cells is associated with mitochondrial dysfunction, oxidative stress sensitivity and premature aging". Mechanisms of Ageing and Development 133 5 (2012): 317-330. http://www.scopus.com/inward/record.url?eid=2-s2.0-84861235436&partnerID=MN8TOARS.
    10.1016/j.mad.2012.03.007
  44. Costa, V.; Ludovico, P.. "Yeast as a platform to uncover ceramide-induced ancient cell death routines". Cell Cycle 11 1 (2012): 14-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-84855695856&partnerID=MN8TOARS.
    10.4161/cc.11.1.18730
  45. Vilaça, R.; Mendes, V.; Mendes, M.V.; Carreto, L.; Amorim, M.A.; de Freitas, V.; Moradas-Ferreira, P.; Mateus, N.; Costa, V.. "Quercetin Protects Saccharomyces cerevisiae against Oxidative Stress by Inducing Trehalose Biosynthesis and the Cell Wall Integrity Pathway". PLoS ONE 7 9 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84866522675&partnerID=MN8TOARS.
    10.1371/journal.pone.0045494
  46. Barbosa, A.D.; Osório, H.; Sims, K.J.; Almeida, T.; Alves, M.; Bielawski, J.; Amorim, M.A.; et al. "Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p-deficient cells". Molecular Microbiology 81 2 (2011): 515-527. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960193275&partnerID=MN8TOARS.
    10.1111/j.1365-2958.2011.07714.x
  47. Mannarino, S.C.; Vilela, L.F.; Brasil, A.A.; Aranha, J.N.; Moradas-Ferreira, P.; Pereira, M.D.; Costa, V.; Eleutherio, E.C.A.. "Requirement of glutathione for Sod1 activation during lifespan extension". Yeast 28 1 (2011): 19-25. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650434634&partnerID=MN8TOARS.
    10.1002/yea.1817
  48. Mendes-Ferreira, A.; Sampaio-Marques, B.; Barbosa, C.; Rodrigues, F.; Costa, V.; Mendes-Faia, A.; Ludovico, P.; Leao, C.. "Accumulation of non-superoxide anion reactive oxygen species mediates nitrogen-limited alcoholic fermentation by Saccharomyces cerevisiae". Applied and Environmental Microbiology 76 24 (2010): 7918-7924. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650390268&partnerID=MN8TOARS.
    10.1128/AEM.01535-10
  49. Mesquita, A.; Weinberger, M.; Silva, A.; Sampaio-Marques, B.; Almeida, B.; Leão, C.; Costa, V.; et al. "Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity". Proceedings of the National Academy of Sciences of the United States of America 107 34 (2010): 15123-15128. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956987110&partnerID=MN8TOARS.
    10.1073/pnas.1004432107
  50. Carvalho, S.; Cruz, T.; Santarém, N.; Castro, H.; Costa, V.; Tomás, A.M.. "Heme as a source of iron to Leishmania infantum amastigotes". Acta Tropica 109 2 (2009): 131-135. http://www.scopus.com/inward/record.url?eid=2-s2.0-57849159746&partnerID=MN8TOARS.
    10.1016/j.actatropica.2008.10.007
  51. Mannarino, S.C.; Amorim, M.A.; Pereira, M.D.; Moradas-Ferreira, P.; Panek, A.D.; Costa, V.; Eleutherio, E.C.A.. "Glutathione is necessary to ensure benefits of calorie restriction during ageing in Saccharomyces cerevisiae". Mechanisms of Ageing and Development 129 12 (2008): 700-705. http://www.scopus.com/inward/record.url?eid=2-s2.0-56949105940&partnerID=MN8TOARS.
    10.1016/j.mad.2008.09.001
  52. Almeida, T.; Marques, M.; Mojzita, D.; Amorim, M.A.; Silva, R.D.; Almeida, B.; Rodrigues, P.; et al. "Isc1p plays a key role in hydrogen peroxide resistance and chronological lifespan through modulation of iron levels and apoptosis". Molecular Biology of the Cell 19 3 (2008): 865-876. http://www.scopus.com/inward/record.url?eid=2-s2.0-41649101223&partnerID=MN8TOARS.
    10.1091/mbc.E07-06-0604
  53. Belinha, I.; Amorim, M.A.; Rodrigues, P.; De Freitas, V.; Moradas-Ferreira, P.; Mateus, N.; Costa, V.. "Quercetin increases oxidative stress resistance and longevity in Saccharomyces cerevisiae". Journal of Agricultural and Food Chemistry 55 6 (2007): 2446-2451. http://www.scopus.com/inward/record.url?eid=2-s2.0-34147162375&partnerID=MN8TOARS.
    10.1021/jf063302e
  54. Costa, V.; Quintanilha, A.; Moradas-Ferreira, P.. "Protein oxidation, repair mechanisms and proteolysis in Saccharomyces cerevisiae". IUBMB Life 59 4-5 (2007): 293-298. http://www.scopus.com/inward/record.url?eid=2-s2.0-34248583109&partnerID=MN8TOARS.
    10.1080/15216540701225958
  55. Marques, M.; Mojzita, D.; Amorim, M.A.; Almeida, T.; Hohmann, S.; Moradas-Ferreira, P.; Costa, V.. "The Pep4p vacuolar proteinase contributes to the turnover of oxidized proteins but PEP4 overexpression is not sufficient to increase chronological lifespan in Saccharomyces cerevisiae". Microbiology 152 12 (2006): 3595-3605. http://www.scopus.com/inward/record.url?eid=2-s2.0-33845969473&partnerID=MN8TOARS.
    10.1099/mic.0.29040-0
  56. Harris, N.; Bachler, M.; Costa, V.; Mollapour, M.; Moradas-Ferreira, P.; Piper, P.W.. "Overexpressed Sod1p acts either to reduce or to increase the lifespans and stress resistance of yeast, depending on whether it is Cu2+-deficient or an active Cu,Zn-superoxide dismutase". Aging Cell 4 1 (2005): 41-52. http://www.scopus.com/inward/record.url?eid=2-s2.0-23844463622&partnerID=MN8TOARS.
    10.1111/j.1474-9726.2005.00142.x
  57. Harris, N.; Costa, V.; MacLean, M.; Mollapour, M.; Moradas-Ferreira, P.; Piper, P.W.. "MnSOD overexpression extends the yeast chronological (G0) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells". Free Radical Biology and Medicine 34 12 (2003): 1599-1606. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037683664&partnerID=MN8TOARS.
    10.1016/S0891-5849(03)00210-7
  58. Costa, V.M.V.; Amorim, M.A.; Quintanilha, A.; Moradas-Ferreira, P.. "Hydrogen peroxide-induced carbonylation of key metabolic enzymes in Saccharomyces cerevisiae: The involvement of the oxidative stress response regulators Yap1 and Skn7". Free Radical Biology and Medicine 33 11 (2002): 1507-1515. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036890134&partnerID=MN8TOARS.
    10.1016/S0891-5849(02)01086-9
  59. Costa, V.; Moradas-Ferreira, P.. "Oxidative stress and signal transduction in Saccharomyces cerevisiae: Insights into ageing, apoptosis and diseases". Molecular Aspects of Medicine 22 4-5 (2001): 217-246. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034777854&partnerID=MN8TOARS.
    10.1016/S0098-2997(01)00012-7
  60. Moradas-Ferreira, P.; Costa, V.. "Adaptive response of the yeast Saccharomyces cerevisiae to reactive oxygen species: Defences, damage and death". Redox Report 5 5 (2000): 277-285. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033646709&partnerID=MN8TOARS.
  61. Santos, M.A.S.; Cheesman, C.; Costa, V.; Moradas-Ferreira, P.; Tuite, M.F.. "Selective advantages created by codon ambiguity allowed for the evolution of an alternative genetic code in Candida spp.". Molecular Microbiology 31 3 (1999): 937-947. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032911874&partnerID=MN8TOARS.
    10.1046/j.1365-2958.1999.01233.x
  62. Costa, V.; Amorim, M.A.; Reis, E.; Quintanilha, A.; Moradas-Ferreira, P.. "Mitochondrial superoxide dismutase is essential for ethanol tolerance of Saccharomyces cerevisiae in the post-diauxic phase". Microbiology 143 5 (1997): 1649-1656. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030997844&partnerID=MN8TOARS.
  63. Moradas-Ferreira, P.; Costa, V.; Piper, P.; Mager, W.. "The molecular defences against reactive oxygen species in yeast". Molecular Microbiology 19 4 (1996): 651-658. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030041567&partnerID=MN8TOARS.
  64. Costa, V.; Reis, E.; Quintanilha, A.; Moradas-Ferreira, P.. "Acquisition of ethanol tolerance in Saccharomyces cerevisiae: The key role of the mitochondrial superoxide dismutase". Archives of Biochemistry and Biophysics 300 2 (1993): 608-614. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027291399&partnerID=MN8TOARS.
    10.1006/abbi.1993.1084
  65. Moradas Ferreira, P.; Costa, V.; Guerreiro, P.; Rodrigues Pousada, C.. "Heat shock effect on glutathione and superoxide dismutase in Tetrahymena pyriformis". Cell Biology International Reports 16 1 (1992): 19-26. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026584502&partnerID=MN8TOARS.
    10.1016/S0309-1651(06)80152-9
Thesis / Dissertation
  1. Costa, Vítor. "Oxidative stress in Saccharomyces cerevisiae: molecular mechanisms of ethanol and hydrogen peroxide stress responses". PhD, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 1998.
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2023/10 Solutions, enablers and barriers to digitally enhanced learning implemented in biochemistry and molecular biology education as a consequence of the COVID-19 pandemic: a rapid review in progress Symposium on Pedagogical Innovation in Biosciences - How to Engage Students in Our Practices?
Portuguese Biochemical Society (Aveiro, Portugal)
2023/07/09 Iron overload impairs autophagy and decreases lifespan in the yeast model of Niemann-Pick type C1 47th FEBS Congress
(Tours, France)
2022/10 Phosphoproteomic analysis of vacuoles and deregulation of vesicle trafficking and iron homeostasis in a Niemann-Pick type C1 yeast model Microbiologia2022
Sociedade Portuguesa de Microbiologia (Lisboa, Portugal)
2022/07 Phosphoregulation of the ATP synthase beta subunit contributes to mitochondrial respiration for G2/M progression The Biochemistry Global Summit
IUBMB-FEBS-PABMB Congress (Lisboa, Portugal)
2021/10 Cell cycle-dependent regulation of ATP synthase beta subunit XXI Congresso Nacional de Bioquímica
(Évora, Portugal)
2021/07 Investigating the function of the Anaphase Promoting Complex ubiquitin ligase in the regulation of mitochondrial ATP synthase beta subunit 45th FEBS Congress
(Ljubljana, Slovenia)
2021/07 Nutrient sensing pathways and cytosolic pH regulate a transcriptional circuit for lipid droplet formation 45th FEBS Congress
(Ljubljana, Slovenia)
2019/10 Bioactive sphingolipids, mitochondrial function and aging: insights from yeast models 11th Symposium on Metabolism - Ageing & Metabolism
Faculdade de Medicina, Universidade do Porto (Porto, Portugal)
2019/06 Sphingolipid signalling and oxidative stress in yeast cell death and ageing Advanced course “Mammalian and yeast cells as complementary cell models in Programmed Cell Death”
Universidade do Minho, Centro de Biologia Molecular e Ambiental (Braga, Portugal)
2018/06/08 Pkh1p-Ypk1p and Pkh1p-Sch9p pathway activation underlies mitochondrial-dependent regulated cell death induced by acetic acid XXI Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Braga, Portugal)
2018/06/08 Dephosphorylation of the ATP synthase subunit Atp2 by the Ser/Thr protein phosphatase Sit4p contributes to the regulation of mitochondrial function XXI Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Braga, Portugal)
2018/06/06 Pkh1-dependent activation of Ypk1 is triggered by membrane stress in a yeast model of Niemann-Pick type C1 disease XXI Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Braga, Portugal)
2018/06 Sphingolipid signalling and oxidative stress in yeast cell death and ageing Advanced course “Mammalian and yeast cells as complementary cell models in Programmed Cell Death”
Universidade do Minho, Centro de Biologia Molecular e Ambiental (Braga, Portugal)
2018/03/24 Bioquímicos@XXI XI Encontro Nacional de Estudantes de Bioquímica (ENEBIOQ)
Universidade do Porto (Porto, Portugal)
2017/08 The Hog1p kinase regulates Aft1p transcription factor to control iron accumulation 28th International Conference on Yeast Genetics and Molecular Biology
(Prague, Czech Republic)
2017/06 Bioactive sphingolipids, nutrient signaling and mitochondrial function in yeast SINAL 2017 - 8th Meeting on Signal Transduction
(Lisboa, Portugal)
2017/06 Sphingolipid signalling and oxidative stress in yeast cell death and ageing Advanced course “Mammalian and yeast cells as complementary cell models in Programmed Cell Death”
Universidade do Minho, Centro de Biologia Molecular e Ambiental (Braga, Portugal)
2017/05/11 Molecular signaling, mitochondria and cell death in Saccharomyces cerevisiae: regulation by bioactive sphingolipids Jornadas da Bioquímica
Universidade de Évora (Évora, Portugal)
2017 Phosphoproteomic screening identifies ATP synthase subunit beta as a target of the yeast type 2A-like protein phosphatase Sit4p First International GIBB (Gruppo Italiano di Biomembrane e Bioeergetica) Meeting
(Catania, Italy)
2016/06 Sphingolipid signalling and oxidative stress in yeast cell death and ageing Advanced course “Mammalian and yeast cells as complementary cell models in Programmed Cell Death”
Universidade do Minho, Centro de Biologia Molecular e Ambiental (Braga, Portugal)
2015/10 The ceramide activated protein phosphatase Sit4p impairs sphingolipid dynamics, mitochondrial function and lifespan in the yeast model of Niemann-Pick type C1 11th International Meeting on Yeast Apoptosis
(Porto, Portugal)
2015/09 Identification of the F1Fo ATP synthase complex ß Subunit as a potential target for the phosphatase Sit4p, impacting on mitochondrial function in yeast 27th International Conference on Yeast Genetics and Molecular Biology
(Levico Terme (Trento), Italy)
2015/07 Sphingolipid signalling and oxidative stress in yeast cell death and ageing Advanced course “Mammalian and yeast cells as complementary cell models in Programmed Cell Death”
Universidade do Minho, Centro de Biologia Molecular e Ambiental (Braga, Portugal)
2014/12/17 The yeast homologue of mammalian protein phosphatase 6 (PP6) Sit4p deregulates macroautophagy, mitophagy and mitochondrial dynamics in response to ceramide signaling in isc1¿ cells XVIII Congresso Nacional de Bioquímica
(Coimbra, Portugal)
2014/10 Oxidative stress responses in Saccharomyces cerevisiae: role of sphingolipid signaling International Symposium on Fungal Stress
(Vale do Paraíba, São José dos Campos, Brazil)
2014/07/11 Role of Sit4p-dependent protein dephosphorylation in the regulation of mitochondrial function and yeast lifespan XX Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Lisboa, Portugal)
2014/07 Cross-talk between sphingolipid and nutrient signaling pathways: new clues to old yeast XX Jornadas de Biologia de Leveduras “Professor Nicolau van Uden”
(Lisboa, Portugal)
2014/06 Sphingolipid signalling and oxidative stress in yeast cell death and ageing Advanced course “Mammalian and yeast cells as complementary cell models in Programmed Cell Death”
Universidade do Minho, Centro de Biologia Molecular e Ambiental (Braga, Portugal)
2013/12/06 Ceramide metabolism modulates mitochondrial outer membrane permeabilization and apoptosis Congresso Nacional MicroBiotech13
(Aveiro, Portugal)
2013/12/06 Phosphoproteome analysis to unravel the role of the ceramide-activated protein phosphatase Sit4p in mitochondrial function and lifespan in yeast Congresso Nacional MicroBiotech13
(Aveiro, Portugal)
2013/10 The role of sphingolipid signaling in mitochondrial dysfunctions and reduced chronological lifespan in the yeast model of Niemann-Pick type C1 7th International Ceramide Conference
(Montauk, NY, United States)
2013/10 Activation of the protein phosphatase Sit4p impairs macroautophagy, mitophagy and mitochondrial dynamics in isc1¿ cells 7th International Ceramide Conference
(Montauk, NY, United States)
2013/06 Sphingolipid signalling and oxidative stress in yeast cell death and ageing Advanced course “Mammalian and yeast cells as complementary cell models in Programmed Cell Death”
Universidade do Minho, Centro de Biologia Molecular e Ambiental (Portugal)
2011/12 Sphingolipid signaling, redox homeostasis and lifespan in yeast Congresso Nacional MicroBiotech11
Portuguese Society of Microbiology (Braga, Portugal)
2011/07 Isc1p-dependent modulation of apoptosis induced by acetic acid in yeast 25th International Conference on Yeast Genetics and Molecular Biology
(Kortowo-Olsztyn, Poland)
2011/06 Oxidative stress and ageing in yeast Postgraduate course “Biomarker discovery using multiplexed proteomic technology”
Universidade do Minho, Centro de Biologia Molecular e Ambiental (Braga, Portugal)
2011/03 Role for Sit4p-dependent mitochondrial dysfunction in mediating the shortened chronological lifespan and oxidative stress sensitivity of Isc1p deficient cells 6th Charleston Ceramide Conference
(Villars-sur-Ollon, Switzerland)
2010/12/15 Isc1 plays a key role in hydrogen peroxide resistance and lifespan through Hog1-dependent modulation of the cell wall integrity pathway XVII Congresso Nacional de Bioquímica
(Porto, Portugal)
2010/11 Unraveling the molecular aspects of Niemann-Pick type C VII International Symposium of Portuguese Society of Metabolic Diseases
Portuguese Society of Metabolic Diseases (Vilamoura, Portugal)
2009/06/19 Protective effect of pomegranate juice against oxidative stress in Saccharomyces cerevisiae XVII Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Braga, Portugal)
2009/06/19 Isc1-dependent regulation of the cell wall integrity pathway is required for oxidative stress resistance and chronological ageing in yeast XVII Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Braga, Portugal)
2009/03 Yeast Lcb5p sphingosine kinase regulates hydrogen peroxide resistance and chronological lifespan Charleston Ceramide Conference
(Charleston, South Carolina, United States)
2009/02/05 Effect of polyphenols isolated from pomegranate in protecting against oxidative stress and aging 6ªs Jornadas de Bebidas e Saúde
(Porto, Portugal)
2008/05/15 Isc1-dependent sphingolipid signalling during oxidative stress and chronological ageing in yeast XVI Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Vimieiro, Portugal)
2008/02/14 Protective effect of polyphenols present in drinks on cell aging 5ªs Jornadas de Bebidas e Saúde
(Porto, Portugal)
2007/11 Oxidative stress, cell signalling and ageing in Saccharomyces cerevisiae LINK-AGE Meeting and IBMC Symposium “The free radical theory of ageing – 50 years and beyond: a tribute to Denham Harman”
(Porto, Portugal)
2007/05 Oxidative stress and aging: nutrient signaling and protective effect of natural antioxidants Postgraduate course “Oxidative stress”
Universidade do Porto, Faculdade de Medicina (Porto, Portugal)
2007/02/02 Protective effect of tannins and quercetin on cell aging 4ªs Jornadas de Bebidas e Saúde
(Porto, Portugal)
2006/10 Saccharomyces cerevisiae as a model in the study of diseases associated with oxidative stress and aging VIII Jornadas de Biologia Aplicada
Universidade do Minho (Braga, Portugal)
2006/05/25 Role of glutathione in the increase of chronological longevity induced oxidative stress XIV Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Évora, Portugal)
2006/05/25 Role of the ceramide-activated protein phosphatase in the response to oxidative stress and aging in Saccharomyces cerevisiae XIV Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Évora, Portugal)
2006/05/25 Oxidative stress and chronological aging in Saccharomyces cerevisiae: protective effect of quercetin XIV Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Évora, Portugal)
2006/05/25 Role of Isc1 sphingomyelinase in cell death associated with oxidative stress and aging XIV Jornadas de Biologia de Levedura “Professor Nicolau van Uden”
(Évora, Portugal)
2006 The yeast Saccharomyces cerevisiae as a model in the study of diseases associated with oxidative stress and aging VIII Jornadas de Biologia Aplicada
Universidade do Minho (Braga, Portugal)
2005/02/01 Natural antioxidants, oxidative stress and aging 2ªs Jornadas de Bebidas e Saúde
Faculdade de Farmácia, Universidade do Porto (Porto, Portugal)
2004/05/13 The deficiency in the phosphosphingolipid phospholipase C Isc1 decreases oxidatives resistance and chronological life-span 12as Jornadas de Biologia de Leveduras "Prof. Nicolau Van Uden"
(Aveiro, Portugal)
2004/05/12 Oxidative damage, cell signalling and ageing in Saccharomyces cerevisiae Workshop on Oxidative Stress
(Rio de Janeiro, Brazil)
2003/11 Defying death after oxidative damage - a yeast global view Congresso Nacional de Microbiologia
Portuguese Society of Microbiology (Tomar, Portugal)
2003/05/29 Transcriptional response and glyceraldehyde-3-phosphate dehydrogenase turnover during recovery of S. cerevisiae cells from hydrogen peroxide stress 11ªs. Jornadas de Biologia de Leveduras “Professor Nicolau van Uden”
(Bragança, Portugal)
2003 Stress in yeast - from research to biological applications Ciência Viva
Escola Secundaria Almeida Garrett (V. N. de Gaia, Portugal)
2002/12/05 Sphingolipid signalling in stress resistance and chronological life-span in Saccharomyces cerevisiae: the role of Isc1p XIII Congresso Nacional de Bioquímica
(Lisboa, Portugal)
2001/12/13 Molecular mechanisms associated with recovery of S. cerevisiae cells from oxidative stress 5º Congresso de Radicais Livres em Química, Biologia e Medicina
(Porto, Portugal)
2001/09 Oxidative stress response of Saccharomyces cerevisiae cells Joint Meeting of Yeast Genetics and Physiology and Emerging Fermentation Systems Sub-Groups
EBC Brewing Science Group (Braga, Portugal)
2000/06 Ageing in yeast Advanced course “Stress and ageing in animals and microorganisms”
Universidade do Porto, Instituto de Biologia Molecular e Celular (Porto, Portugal)
1999/05/21 Hydrogen peroxide stress in Saccharomyces cerevisiae: dynamics of oxidized proteins 7as Jornadas de Biologia de Leveduras “Professor Nicolau van Uden”
(Lisboa, Portugal)
1999/05 Ageing in yeast Advanced course “Genetics and biochemistry of ageing”
Universidade do Porto, Instituto de Biologia Molecular e Celular (Porto, Portugal)
1998/09 Oxidative stress in yeast 19th International Specialized Symposium on Yeast
(Braga, Portugal)
1997/05 Ageing in yeast Advanced course “Regulatory mechanisms involved in cell ageing and death”
Universidade do Porto, Centro de Citologia Experimental (Porto, Portugal)
1996/09 Ethanol stress response in yeast: induction of antioxidant defences III Congresso Ibérico de Biotecnologia
(Spain)
1995/04/08 Role of antioxidant defenses in ethanol resistance of S. cerevisiae in the stationary phase 3ªs. Jornadas de Biologia de Leveduras “Professor Nicolau van Uden”
(Sintra, Portugal)
1994/05/20 Regulation of superoxide dismutases by YAP1 and YAP2 in Saccharomyces cerevisiae: correlation with hydrogen peroxide resistance 2ªs. Jornadas de Biologia de Leveduras “Professor Nicolau van Uden”
(Braga, Portugal)
1993/06 Oxidative stress in Saccharomyces cerevisiae 1º Congresso de Radicais Livres em Química, Biologia e Medicina
(Lisboa, Portugal)
1993/02/28 Ethanol toxicity in Saccharomyces cerevisiae is correlated with reactive oxygen species 1ªs. Jornadas de Biologia de Leveduras “Professor Nicolau van Uden”
(Luso, Portugal)

Supervision

Thesis Title
Role 		Degree Subject (Type)
Institution / Organization
2019/03 - 2024/12/31 Physiology of Lipid Droplets in Cellular Lipid Metabolism and Disease
Supervisor
 Junior Investigator (Other)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2019/01 - 2024/02 Phosphoregulation of the yeast lysosome-like vacuole and its role in lifespan.
Supervisor
 Biologia Molecular e Celular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/04 - 2023/07 Impact of Ncr1 deficiency in Snf1 activity
Supervisor
 Magistere de Génétique, Université Paris Cité (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022/09 - 2023/07 Role of Vps27 in the regulation of vacuolar function and chronological lifespan by the Sit4 protein phosphatase
Supervisor
 Biochemistry (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2018/11 - 2023/02 Cross-regulation of mitochondrial function and cell cycle progression in budding yeast
Co-supervisor
 Biologia Molecular e Celular (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021/09 - 2022/09 Development of a yeast-based screening assay for inhibitors of the kinase chaperone Cdc37
Co-supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/09 - 2021/12 Aggregation and toxicity of seipin/BSCL2 N88S mutant associated with motor neuron degeneration
Co-supervisor of Verónica Andrade Nogueira
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020/09 - 2021/12 alpha-ketoglutarate, amino acid homeostasis and lifespan in a yeast model of Niemann-Pick type C1
Supervisor of Rafaela Silva Costa
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/09 - 2019/11 Role of the yeast frequenin (Frq1) as ceramide sensor in cell death and aging
Supervisor
 Biologia Celular e Molecular (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2019/02 - 2019/09 Unraveling the role of Frq1 binding to ceramide as a switch between life and death
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/09 - 2018/12 The role of eisosomes and calcineurin in a yeast model of Niemann-Pick type C1
Co-supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/01 - 2018/12 Lipid metabolic switch in cancer models of mitochondrial dysfunction
Co-supervisor
 Postdoc (Other)
Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal
2016/06 - 2018/05 Sphingolipid signaling and autophagy in Niemann-Pick type C.
Supervisor
 Postdoc (Other)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2016/09 - 2017/12 TORC2/Pkh1-Ypk1 pathway is activated in a yeast model of Niemann-Pick type C1 disease
Co-supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017/02 - 2017/09 Cross-talk between calcium-calcineurin signaling and sphingolipid metabolism in the yeast model of Niemann-Pick type C disease
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/07 - 2017/09 Sphingolipid signaling and mitochondrial function during ageing in yeast
Supervisor
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2014 - 2017 The role of ceramides in the mitochondrial apoptotic pathway induced by acetic acid.
Co-supervisor
 Biologia Molecular e Ambiental (PhD)
Universidade do Minho Centro de Biologia Molecular e Ambiental, Portugal
2015/09 - 2016/12 Aromatic alcohol and polyalcohol dehydrogenases in Patella vulgata and other gastropods (Mollusca)
Co-supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/06 - 2016/12 Regulation of FoF1 ATP synthase by phosphorylation during aging
Supervisor
 Postdoc (Other)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2016/02 - 2016/09 Impact of the regulation of the voltage dependent anion channel (VDAC) in the longevity of Saccharomyces cerevisiae
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 - 2016 Phenolic compounds and cellular redox homeostasis: role in antioxidant protection and anti-tumoral effects
Supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014/09 - 2015/12 Sphingolipid metabolism, Sit4p and TORC1 in the yeast model of Niemann-Pick type C1 disease
Supervisor
 Bioquímica (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2015/02 - 2015/09 Role of sphingolipid signalling and Sit4-dependent protein dephosphorylation in the regulation of mitochondrial function and yeast lifespan
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/05 - 2015/08 The role of ceramide signaling in the yeast model of Niemann-Pick type C disease
Supervisor
 Postdoc (Other)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2013/06 - 2015/05 Role of the yeast neutral sphingomyelinase in mitochondria function and iron homeostasis
Supervisor
 Postdoc (Other)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2011 - 2015 Crosstalk between ceramide and cell signalling pathways controlling chronological lifespan in yeast.
Supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013/09 - 2014/12 Role of sphingolipid signaling and Sit4-dependent protein dephosphorylation in the regulation of mitochondrial function and yeast lifespan
Co-supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 - 2014 Interplay between sphingolipid and nutrient signaling in the Niemann-Pick type C1 disease: new clues from a yeast cell model
Supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012/09 - 2013/12 Regulation of mitochondrial function by Isc1p and Sch9p in Saccharomyces cerevisiae
Supervisor
 Biologia Celular e Molecular (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2013/02 - 2013/09 Study of phenotypes of saccharomyces cerevisiae isc1 strain
Supervisor
 Bioengenharia (Other)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013/02 - 2013/09 Role of the Pkh1p/-Sch9p pathway on the premature aging and mitochondrial function in the yeast model of Niemann-Pick C1 disease
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013/02 - 2013/09 Regulation of mitochondrial function by Isc1p and Sch9p in Saccharomyces cerevisiae
Supervisor
 Biologia Celular e Molecular (Other)
Universidade do Porto Faculdade de Ciências, Portugal
2011/09 - 2012/12 Role of the yeast orthologue of Niemann-Pick C1 protein in oxidative stress resistance and mitochondrial function
Supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010/09 - 2011/12 Characterization of the role of sphingolipids in the modulation of acetic acid-induced apoptosis
Co-supervisor
 Genética Molecular (Master)
Universidade do Minho Escola de Ciências, Portugal
2010/09 - 2011/12 Using yeast to study the role of ceramide pathway in the regulation of mammalian protein kinase C isoforms
Co-supervisor
 Genética Molecular (Master)
Universidade do Minho Escola de Ciências, Portugal
2010/09 - 2011/12 Regulation of vacuolar function by Isc1p in Saccharomyces cerevisiae – role in cell death induced by oxidative stress and aging
Supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010/09 - 2011/12 Role of Ncr1p in endoplasmic reticulum stress response in Saccharomyces cerevisiae
Supervisor
 Contaminação e Toxicologia Ambientais (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009/01 - 2011/12 Antioxidant and antiradical characterization of polyphenolic compounds; bioavailability, biological properties and cell signalling
Supervisor
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2008 - 2011 The role of Isc1p in signal transduction during oxidative stress and chronological aging in yeast
Supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009/09 - 2010/12 Cell signalling and apoptose induced by acetic acid: role of the ceramide pathway and lipid rafts
Supervisor
 Contaminação e Toxicologia Ambientais (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009/09 - 2010/12 Role of Isc1p in cell signaling mediated by the protein kinase C and HOG MAPK pathways – effect on cell death induced by oxidative stress and ageing
Supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009/02 - 2009/09 Role of Ncr1p in oxidative stress resistance in Saccharomyces cerevisiae
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007/09 - 2008/12 Protective effect of polyphenols present in the diet against oxidative stress and ageing
Supervisor
 Bioquímica (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2004 - 2008 Involvement of sphingolipid signalling in chronological lifespan and cell death in Saccharomyces cerevisiae
Supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007/02 - 2007/09 Protective effect of food polyphenols on cell aging: antioxidant characterization of new dyes for food industry application
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2006/02 - 2006/09 Signaling function of Isc1 sphingomyelinase and its importance in cell death associated with oxidative stress and aging in Saccharomyces cerevisiae
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2006/06 - 2006/07 Progeria
Supervisor
 Medicina (Other)
Universidade do Minho Escola de Medicina, Portugal
2005/02 - 2005/09 Protective effect of quercetin, catechins and procyanidins on cell aging under oxidative stress conditions
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2005/02 - 2005/09 Signaling role of ceramide in Saccharomyces cerevisiae aging
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2004/02 - 2004/09 Study of the protective function of food polyphenols in cell aging under oxidative stress conditions
Supervisor
 Química (Degree)
Universidade do Porto Faculdade de Ciências, Portugal
2000 - 2004 Oxidative stress in Saccharomyces cerevisiae: the key role of Isc1p sphingomyelinase in cell resistance, and the molecular mechanisms associated to the recovery from hydrogen peroxide stress
Co-supervisor
 Ciências Biomédicas (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2003/02 - 2003/09 Role of sphingosine-1-phosphate in programmed cell death associated with aging and oxidative stress in Saccharomyces cerevisiae
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2002/02 - 2002/09 Role of protein kinase C and phospholipases in oxidative stress adaptation in Saccharomyces cerevisiae
Supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2000/02 - 2000/09 Role of ascorbate oxidase and glutathione S-transferase in suppressing apoptosis induced by BAX gene expression in S. cerevisiae
Co-supervisor
 Microbiologia (Degree)
Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
1998/02 - 1998/09 Study of stress resistance in Saccharomyces cerevisiae transformed with Ser-tRNA from Candida albicans
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1996/02 - 1996/09 Role of cytochrome c peroxidase in the acquisition of stress resistance in Saccharomyces cerevisiae
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1995/02 - 1995/09 Study of mechanisms associated with oxidative stress induced by ethanol in Saccharomyces cerevisiae
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1994/02 - 1994/09 Expression of superoxide dismutases and catalase in Saccharomyces cerevisiae cells exposed to hydrogen peroxide: influence of YAP transcription factors
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1992/02 - 1992/09 Oxidative stress in Saccharomyces cerevisiae: effect of hydrogen peroxide
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1991/02 - 1991/09 Relationships between heat stress and ethanol stress in Saccharomyces cerevisiae: synthesis of stress proteins and antioxidant defenses
Co-supervisor
 Bioquímica (Degree)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Event organisation

Event name
Type of event (Role) 		Institution / Organization
2021/11/17 - 2021/11/18 FEBS-SPB-UM symposium "Evidence based teaching in your biomolecular classroom: catalysing student engagement", Universidade do Minho, 17-18/11, 2021. (2021/11/17 - 2021/11/18)
Symposium (Member of the Organising Committee)
 Universidade do Minho, Portugal

Sociedade Portuguesa de Bioquímica, Portugal
2021/09/13 - 2021/09/24 Tanto mar - Jornadas internacionais de ensino de Bioquímica e Biologia Molecular (2021/09/03 - 2021/09/24)
Workshop (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal

Sociedade Brasileira de Bioquímica e Biologia Molecular, Brazil
2021/03/30 - 2021/03/30 Virtual Workshop on Biochemistry of Ageing (2021/03/30 - 2021/03/30)
Symposium (Member of the Organising Committee)
 Sociedade Portuguesa de Bioquímica, Portugal
2019/11/13 - 2019/11/13 Training and Research in Biochemistry - Pedro Moradas Ferreira, 4 decades of activities at U. Porto (2019/11/13 - 2019/11/13)
Symposium (Member of the Organising Committee)
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014/09/18 - 2014/09/18 Sphingolipids in Health and Disease (2014/09/18 - 2014/09/18)
Symposium (President of the Organising Committee)
 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2010/12/15 - 2010/12/17 XVII Congresso Nacional de Bioquímica (2010/12/15 - 2010/12/17)
Congress (Member of the Organising Committee)
 Portuguese Biochemical Society, Portugal
2007/11/28 - 2007/12/01 LINK-AGE Meeting and IBMC Symposium. The free radical theory of ageing - 50 years and beyond: a tribute to Denham Harman (2007/11/28 - 2007/12/01)
Congress (Member of the Organising Committee)
 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2007/10/22 - 2007/10/22 Lipid Signalling in Health and Disease (2007/10/22 - 2007/10/22)
Workshop (President of the Organising Committee)
 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2005/11/30 - 2005/12/03 Congresso Nacional Micro’05 e Biotec’05 (2005/11/30 - 2005/12/03)
Congress (Member of the Organising Committee)
 Portuguese Society of Microbiology, Portugal
2004/10/27 - 2004/10/29 Oxidative stress and cell signalling (2004/10/27 - 2004/10/29)
Workshop (Member of the Organising Committee)
 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2003/10/27 - 2003/10/29 Active teaching and learning in the biomolecular sciences (2003/10/27 - 2003/10/29)
Workshop (Member of the Organising Committee)
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2002/05/06 - 2002/05/10 Advanced course on “Oxidative stress and disease: an advanced practical course" (2002/05/06 - 2002/05/10)
Other (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2001/12/13 - 2001/12/15 5th Congress of Free Radicals in Chemistry, Biology and Medicine (2001/12/13 - 2001/12/15)
Congress (Member of the Organising Committee)
 Universidade do Porto Faculdade de Farmácia, Portugal
2001/11/07 - 2001/11/10 2nd International Meeting on Cellular Responses to Oxidative and Osmotic Stress (2001/11/07 - 2001/11/10)
Workshop (Member of the Organising Committee)
 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
1996/05/17 - 1996/05/18 4as Jornadas de Biologia de Leveduras "Prof. Nicolau Van Uden" (1996/05/17 - 1996/05/18)
Symposium (Member of the Organising Committee)
 Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

Event participation

Activity description
Type of event 		Event name
Institution / Organization
2022/09/05 - 2022/09/09 Research project under the scope of Junior University - School of Life and Health Sciences. Laboratory project developed by young people who in the previous year attended the 10th or 11th year of schooling.
Other
 School of Life and Health Sciences
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/09/02 - 2019/09/07 Research project under the scope of Junior University - School of Life and Health Sciences. Laboratory project developed by young people who in the previous year attended the 10th or 11th year of schooling.
Other
 Junior University
Universidade do Porto, Portugal
2018/09/03 - 2018/09/08 Research project under the scope of Junior University - School of Life and Health Sciences. Laboratory project developed by young people who in the previous year attended the 10th or 11th year of schooling.
Other
 Junior University
Universidade do Porto, Portugal
2018/01/25 - 2018/01/25 Workshop on education
Workshop
 Socrative Application: assess student learning
Universidade do Porto, Portugal
2018/01/19 - 2018/01/19 Meeting on education
Workshop
 Evolution of Pedagogy in Higher Education
Universidade do Porto, Portugal
2018/01/12 - 2018/01/12 Workshop on education
Workshop
 Construction of multiple choice questions to test objectives of greater complexity
Universidade do Porto, Portugal
2017/09/04 - 2017/09/09 Research project under the scope of Junior University - School of Life and Health Sciences. Laboratory project developed by young people who in the previous year attended the 10th or 11th year of schooling.
Other
 Junior University
Universidade do Porto, Portugal
2016/06/23 - 2016/06/23 Workshop on education
Workshop
 It´s hip to flip! Turning your class upside-down for learning
Universidade do Porto, Portugal
2006/06/30 - 2006/06/30 Meeting on education
Meeting
 Use of the WebCT VISTA platform - initial training
Universidade do Porto, Portugal
2001/03/28 - 2001/03/28 Meeting on education
Meeting
 II Interactive E-learning Meeting
Universidade do Porto, Portugal
1999/10/30 - 1999/10/31 Meeting on Biochemical Education
Meeting
 International Meeting on Biochemical Education at the University Level
Universidade de Lisboa, Portugal

Jury of academic degree

Topic
Role 		Candidate name (Type of degree)
Institution / Organization
2024 The role of KRAS mutations in the modulation of BAX and glycolytic metabolism using yeast as a model
(Thesis) Main arguer
 Anabela Araújo Ferreira (PhD)
Universidade do Minho, Portugal
2024 Regulation of the Spindle Assembly Checkpoint by mitotic kinases
Thesis Member
 Ana Sofia Cunha e Silva (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024 The novel Drosophila melanogaster ascorbic acid synthesis and transport mechanisms
Thesis Member
 Pedro Miguel Barros Duque (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024 The role of the MIT/TFE family in melanoma
Thesis Member
 Diogo Bernardes Dias (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2024 Decoding Heparan Sulfate unique structural epitopes involved in cancer cell signaling
Thesis Member
 Catarina Marques Gonçalves (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023/12 Assessing the impact of fluoroacetic acid on mitochondrial function using Neurospora crassa as a model organism
(Thesis) Main arguer
 João Pedro Silva Monteiro (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2023 Novel Psychoactive Substances and Parkinson's Disease: Molecular and cellular mechanisms of a-synuclein aggregation in the presence of synthetic cannabinoids and cathinones
(Thesis) Arguer
 Carla Filipa da Silva Ferreira (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2023 Uncovering cell death induction mechanisms and anticancer properties of novel benzo[a]phenoxazine derivatives
(Thesis) Main arguer
 João Carlos Canossa Ferreira (PhD)
Universidade do Minho, Portugal
2023 Recoding the Saccharomyces cerevisiae genome
(Thesis) Main arguer
 Ana Rita Guimarães Rodrigues da Silva (PhD)
Universidade de Aveiro, Portugal
2023 Unraveling the role of mitochondrial TERT in a thyroid cancer cell line
(Thesis) Main arguer
 Ana Sofia Moreira Chantre (Master)
Instituto Politécnico do Porto, Portugal
2023 Combined effects of multiple stressors in wild marine mussels exposed in real scenarios
President of the jury
 Maria Inês Samara (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022 The role of cell signalling during yeast chronological lifespan.
(Thesis) Main arguer
 Hélder Ricardo Cardoso Pereira (PhD)
Universidade do Minho, Portugal
2022 Mechanistic insights into age-associated chromosome mis-segregation and senescence
Thesis Member
 Monika Barroso Vilares (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2022 Efeitos de nanoplásticos, isoladamente e em mistura com dicromato de potássio, no crescimento da microalga Chlorella vulgaris
President of the jury
 Rui Filipe da Costa Ribeiro (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 Novel insights on the interaction of lactoferrin with proton pumping ATPases towards understanding its antifungal and anticancer activities
(Thesis) Main arguer
 Cátia Sofia dos Santos Pereira (PhD)
Universidade do Minho, Portugal
2021 Contaminação por partículas suspeitas de serem plásticos e microplásticos e efeitos biológicos na população de Phorcus lineatus da costa noroeste de Portugal
President of the jury
 Ana Patrícia Gomes (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 Isolation and identification of toxin-producing fungi associated with macroalgae
President of the jury
 Toxicologia e Contaminação AmbientaisTiago Nuno Matos Vale Pereira Guimara~es (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 Unveiling biosynthetic pathways for the production of extracellular polymeric substances (EPS) in cyanobacteria and possible applications of the polymers
Thesis Member
 Marina Patrícia Fonseca Santos (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 Role and molecular mechanisms of a novel sigma factor
Thesis Member
 Rute Patrícia Martins Barbosa de Oliveira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 Candida albicans gene mistranslation as a modulator of host-pathogn interaction and pathogenesis
Thesis Member
 Edgar Da Silva Lopes (PhD)
Universidade de Aveiro, Portugal
2020 Effects of microplastics and other contaminants in freshwater organisms
President of the jury
 Sofia Mendes Ferreira (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 Effects of pesticide formulations containing cypermethrin and tebuconazole, individually and in mixture, on the earthworm Eisenia fetida
President of the jury
 Pedro Alexandre da Rocha Costa (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2020 Assessment of toxicity and behavior of Cu formulations in vineyard soils
President of the jury
 Cristiana Patrícia Gonçalves Paiva (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 Phosphoregulation of the Drosophila tumor suppressor LGL during the cell – cycle
Thesis Member
 Sara Gomes Moreira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 Drugging p53-impaired tumors: impact of new small molecules targeting p73 and mutant p53
Thesis Member
 Sara Gomes Moreira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 Regulation of alternative polyadenylation in Drosophila melanogaster
Thesis Member
 Marta Sofia dos Santos Oliveira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019 Estudo da interação entre as vias de sinalização dos estrogénios e fatores de crescimento no controle da transcrição dos genes HNRPK, PAWR e PHLDA1
Thesis Member
 Simone Aparecida de Bessa Garcia (PhD)
Universidade do Porto, Portugal
2019 Membrane permeability and aquaporin involvement in oxidative stress and cancer
(Thesis) Main arguer
 Ana Cláudia Rodrigues Fonseca (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2018 The role of YAP and TAZ in sprouting angiogenesis
Thesis Member
 Filipa Ferreira Maia Neto (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 Mechanisms of actin cytoskeletal dynamics in oligodendrocyte biology and myelin formation
Thesis Member
 Maria Manuela Coutinho Alves de Azevedo (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 Potencial tóxico e genotóxico do inseticida imidacloprido em organismos não alvos
Thesis Member
 Yadira Ansoar Rodríguez (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018 Targeted regulation of PKC signaling pathway: Searching for new therapeutic strategies against cancer
(Thesis) Main arguer
 Cláudia Sofia Santos Bessa (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2018 Ecotoxicology of deep sea environments
President of the jury
 Bárbara Marlene Teixeira Pinheiro (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 BEORA – Biotechnology exploitation of orotic acid production
Thesis Member
 Nuno Duarte Fernandes Lima de Carvalho (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 Unravelling genes, the Haa1-signalling pathway and cell envelope properties responsible for the remarkably high acetic acid tolerance of Zygosaccharomyces bailii
(Thesis) Main arguer
 Filipa de Canaveira Roque Baker (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2017 Characterization of ScGup1 partners in the yeast putative Hedgehog-like morphogenic pathway
(Thesis) Main arguer
 Joana Isabel da Silva Tulha Moreira (PhD)
Universidade do Minho, Portugal
2017 Study of the impact of mRNA mistranslation in lipid homeostasis
(Thesis) Main arguer
 Ana Rita Dias Araújo (PhD)
Universidade de Aveiro, Portugal
2016 Phenolic compounds and cellular redox homeostasis: role in antioxidante protection and anti-tumoral effects
Supervisor
 Vanda Rafaela Maio de Sousa Mendes (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 Impact of Limp-2 deficiency on lysosome composition and function
(Thesis) Main arguer
 Paulo Jorge Miranda da Silva Gaspar (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 Unraveling the mechanisms involved in acetate induced apoptosis in colorectal cance
Thesis Member
 Cláudia Suellen Ferro de Oliveira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 Mechanistic insights into adaptation and tolerance to acetic acid in Saccharomyces cerevisiae and Zygosaccharomyces bailii
(Thesis) Main arguer
 Joana Filipa Fernandes Guerreiro (PhD)
Universidade de Lisboa Instituto Superior Técnico, Portugal
2016 The endocannabinoid anandamide and endometrial remodelling: importance of cyclooxygenase-2 metabolites
Thesis Member
 Marta Sofia Sampaio de Almada (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2016 Characterization of intracellular lipid droplets in cancer cells harboring mitochondrial dysfunction: emphasis on fatty acid metabolism
(Thesis) Main arguer
 Pedro Filipe da Silva Pinheiro (Master)
Universidade do Porto Faculdade de Medicina, Portugal
2015 Crosstalk between ceramide and cell signalling pathways controlling chronological lifespan in yeast
Supervisor
 Vítor Hugo Freitas Teixeira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015 The role of Pep4p, the vacuolar yeast protease ortholog of human cathepsin D, in mitochondria-dependent apoptosis
(Thesis) Main arguer
 Helena Paula Fernandes Pereira (PhD)
Universidade do Minho, Portugal
2015 Novel insights on molecular characterization of congenital erythrocytosis
Thesis Member
 Maria Celeste Sena São Miguel Bento Lago de Queiroz (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015 Investigating the neuroprotective effect of plant (poly)phenols in models of Parkinson's disease
Thesis Member
 Diana Leonor Constantino Macedo (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2015 Regulation of peroxisome biogenesis and proliferation: characterization of Pex16p and Pex11pß
(Thesis) Main arguer
 Maria João Ribeiro Cardoso (PhD)
Universidade de Aveiro, Portugal
2015 The link between altered glucosylceramide composition and membrane properties: from membrane biophysics to Gaucher disease
Thesis Member
 Ana Raquel Pinto Varela (PhD)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2015 Study of the Ceramide synthase paralogs in Saccharomyces cerevisiae
(Thesis) Main arguer
 Mallela Shamroop Kumar (PhD)
Université de Fribourg Faculté de sciences et de médecine, Switzerland
2015 The mitochondrial peroxiredoxin of Leishmania - A novel member of the parasite chaperone network, crucial for infection
Thesis Member
 Filipa Daniela Pinheiro Teixeira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015 Contribution to drug discovery and development for tauopathies using yeast as a model
(Thesis) Main arguer
 Marta Isabel Heitor Cerejo (PhD)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2015 Sphingolipid metabolism, Sit4p and TORC1 in the yeast model of Niemann-Pick type C1 disease
Supervisor
 Ivo André Silva Barros (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 Interplay between sphingolipid and nutrient signaling in Niemann-Pick type 1 disease: new clues from a yeast cell model
Supervisor
 Rita Pereira Vilaça (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 Study of the mechanisms of transport and regulation of carboxylic acids in Candida albicans and Candida glabrata
(Thesis) Main arguer
 Sandra Marlene da Silva Mota (PhD)
Universidade do Minho, Portugal
2014 The molecular basis of programmed cell death in Neurospora crassa
Thesis Member
 António Pedro da Rocha Cardoso Gonçalves (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 Oxidative stress in Huntington´s disease knock-in striatal cells
(Thesis) Main arguer
 Márcio José do Coito Ribeiro (PhD)
Universidade de Coimbra, Portugal
2014 The Pex5/Pex7-mediated importo f PTS2-containing matrix proteins: mechanistic insights on Pex7 translocation and recycling steps
Thesis Member
 Tony Alexandre Quinteiros Rodrigues (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014 Study of alternative NADH dehydrogenase and mitochondrial fumarate reductase in Leishmania infantum
(Thesis) Main arguer
 Cleide Vanessa Estupendo Ferreira (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 Phenotypic consequences of genome mistranslation in Candida albicans
(Thesis) Main arguer
 João Manuel Salvador Simões (PhD)
Universidade de Aveiro, Portugal
2013 Transthyretin as a signaling molecule: influence on IGF-IR pathway and 14-3-3¿ metabolismo
Thesis Member
 Marta Virgínia Mota Vieira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013 First molecular and biochemical characterization of the extracellular matrix of Saccharomyces cerevisiae
(Thesis) Main arguer
 Fábio Luís da Silva Faria Oliveira (PhD)
Universidade do Minho, Portugal
2013 Characterization of proteotoxic stress in zebrafish
(Thesis) Main arguer
 Marisa Susete Reverendo Simões (PhD)
Universidade de Aveiro, Portugal
2013 Characterization of the exoproteome of two morphologically distinct cyanobacteria
(Thesis) Main arguer
 Nuno Manuel de Resende Rego Macedo Martins (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2013 The mechanism mediating nuclear translocation of the apoptosis inducing factor (AIF)
(Thesis) Main arguer
 Rita Isabel Costa Cunha (Master)
Universidade do Minho, Portugal
2013 Regulation of mitochondrial function by Isc1p and Sch9p in Saccharomyces cerevisiae
Supervisor
 Tânia Catarina Silva Maia Medeiros (Master)
Universidade do Porto Faculdade de Ciências, Portugal
2012 Molecular pathways of NAD(P)H dehydrogenases in Neurospora crassa mitochondria throughout development
Thesis Member
 Patrícia Alexandra Barreira Carneiro (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 Cellular responses to genome mistranslation
(Thesis) Main arguer
 Tatiana Lima de Vilhena Magalhães Costa (PhD)
Universidade de Aveiro, Portugal
2012 New insight into translation during yeast programmed cell death
Thesis Member
 Maria Alexandra Oliveira da Silva (PhD)
Universidade do Minho, Portugal
2012 Protein aggregation in aging
Thesis Member
 Pedro José Reis Rodrigues (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 Studies on metal acquision in Leishmania infantum
Thesis Member
 Sandra Isabel Pereira de Carvalho (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 STAT3 regulation and functional role in thyroid cancer. Therapeutic implications
(Thesis) Main arguer
 Joana Pinto do Couto e Silva (PhD)
Universidade do Porto Faculdade de Medicina, Portugal
2012 Ammonium toxicity in aging yeast cells reduces chronological life span: cell death mechanisms and nutrient sensing pathways
(Thesis) Main arguer
 Júlia Margarida Raposo Monteiro dos Santos (PhD)
Universidade do Minho, Portugal
2012 Interplay between alpha-synuclein and oxidative stress in Parkinson´s disease cell models
(Thesis) Main arguer
 Rita Catarina Gonçalves Perfeito (PhD)
Universidade de Coimbra, Portugal
2012 mRNA mistranslation and genomic instability
(Thesis) Main arguer
 Ana Filipa Ligeiro de Jesus (Master)
Universidade de Aveiro, Portugal
2012 Analysis of the induction of the cytoprotective Nrf2 signalling pathway in reticuloendothelial cells from iron-treated mice and HFE Haemochomatosis patients
(Thesis) Main arguer
 Filipe Fernandes de Sousa (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 Role of the yeast orthologue of Niemann-Pick C1 protein in oxidative stress resistance and mitochondrial function
Supervisor
 Elísio Matos Silva (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2012 Using yeast to study the role of ceramide pathway in the regulation of mammalian protein kinase C isoforms
Supervisor
 Cláudia Sofia Santos Bessa (Master)
Universidade do Minho, Portugal
2011 The role of Isc1p in signal transduction during oxidative stress and chronological aging in yeast
Supervisor
 António Daniel Cardoso Barbosa (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 Mitochondrial dysfunction: the road to alpha-synuclein oligomerization in Parkinson´s disease
(Thesis) Main arguer
 Ana Raquel Fernandes Esteves (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2011 The role of Mad2 and BubR1 in the spindle assembly checkpoint and mitotic progression
Thesis Member
 Bernard Nunes de Almeida Orr (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 New insights into the effects of caloric restriction on Saccharomyces cerevisiae chronological lifespan
(Thesis) Main arguer
 Ana Maria Macedo Mesquita (PhD)
Universidade do Minho, Portugal
2011 Counteracting toxicity in misfolding disorders: the case of familial amyloidotic polyneuropathy
Thesis Member
 Joana Miguel Teixeira Magalhães (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 Heterologous expression of mammalian proteins in yeast for functional, molecular and pharmacological studies
(Thesis) Main arguer
 Isabel Cristina Loureiro Coutinho (PhD)
Universidade do Porto Faculdade de Farmácia, Portugal
2011 Yap1 in stress caused by excess cobalt in S. cerevisiae
(Thesis) Main arguer
 Soraia Cristina Marques Caetano (Master)
Universidade de Aveiro, Portugal
2011 Antifungal drug resistance driven by mistranslation in yeast
(Thesis) Main arguer
 Ana Rita Dias Araújo (Master)
Universidade de Aveiro, Portugal
2011 Characterization of the role of sphingolipids in the modulation of acetic acid-induced apoptosis
Supervisor
 António Miguel Araújo Rego (Master)
Universidade do Minho, Portugal
2011 Regulation of vacuolar function by Isc1p in Saccharomyces cerevisiae – role in cell death induced by oxidative stress and aging
Supervisor
 João Manuel Pinto de Almeida Ferreira (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 Role of Ncr1p in endoplasmic reticulum stress response in Saccharomyces cerevisiae
Supervisor
 Joana Filipa Madureira Gaifem (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010 Role of Yap8 and Yap1 b-ZIP transcription factors in arsenic stress
(Thesis) Main arguer
 Catarina Sá Almeida Amaral (PhD)
Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica, Portugal
2010 The transport of carboxylic acids in yeasts: from physiology towards structural-functional characterization of permeases
(Thesis) Main arguer
 Neide Marina Vieira Pereira (PhD)
Universidade do Minho, Portugal
2010 Molecular pathophysiology underlying neuronal ceroid liposcinoses: CLN2 and CLN5
(Thesis) Main arguer
 Carlos Bessa (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010 Molecular study of cell degeneration and evolution induced by mRNA mistranslation
(Thesis) Main arguer
 João Cancela de Amorim Falcão Paredes (PhD)
Universidade de Aveiro, Portugal
2010 Cell signalling and apoptose induced by acetic acid: role of the ceramide pathway and lipid rafts
Supervisor
 Ana Margarida Costa (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010 Role of Isc1p in cell signaling mediated by the protein kinase C and HOG MAPK pathways – effect on cell death induced by oxidative stress and ageing
Supervisor
 João Graça (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 Adaptive response of Escherichia coli K12 strains to cadmium-induced oxidative stress
Thesis Member
 Catarina Coutinho Gouveia Lopes Pacheco (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 Elucidation of molecular pathways involved in Saccharomyces cerevisiae apoptotic cell death
(Thesis) Main arguer
 Bruno Miguel Barroso Rodrigues Almeida (PhD)
Universidade do Minho, Portugal
2009 The cytosolic hydroperoxide detoxification system of Leishmania infantum
Thesis Member
 Susana de Freitas Romão (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 Ubiquitination and deubiquitination in the mammalian Pex5-mediated peroxisomal protein import pathway
Thesis Member
 Cláudia Patrícia Oliveira Grou (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 Functional characterization of human Pex7p, a WD protein involved in peroxisomal biogenesis
(Thesis) Main arguer
 Tony Alexandre Quinteiros Rodrigues (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2009 Animal model of Fabry disease: study of early enzyme replacement therapy to prevent the appearance of phenotypic changes
(Thesis) Main arguer
 Inês Isabel Vieira Mendes (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008 Involvement of sphingolipid signalling in chronological lifespan and cell death in Saccharomyces cerevisiae
Supervisor
 Teresa Rodrigues da Cunha Almeida (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008 Mechanisms and control of mRNA turnover in the yeast Saccharomyces cerevisiae
Thesis Member
 Sílvia Daniela da Costa Teixeira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2008 Cross-talk between endoplasmic reticulum and mitochondria in the neurotoxicity induced by amyloid-beta and prion peptides. Implications for the etiopathogenesis of Alzheimer’s disease and Prion disorders
(Thesis) Main arguer
 Elisabete Baptista Ferreiro (PhD)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2008 Protective effect of pomegranate polyphenols and quercetin against oxidative stress in Saccharomyces cerevisiae
Supervisor
 Rita Pereira Vilaça (Master)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007 Therapies in familial amyloidotic polyneuropathy
Thesis Member
 Bárbara Magda Ribeiro Lemos Macedo (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2006 Hydroperoxide metabolism in Leishmania infantum
Thesis Member
 Helena Maria de Sousa Castro (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2006 Biochemical and physiological responses of the aquatic fungi Fontanospora fusiramosa and Flagellospora curta to cadmium, copper and zinc
(Thesis) Main arguer
 Luís Miguel Guimarães Soares (PhD)
Universidade do Minho, Portugal
2006 Molecular studies of longevity-associated genes in human cells
(Thesis) Main arguer
 Rita João Machado de Oliveira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2006 Iron uptake by amastigotes from Leishmania infantum
(Thesis) Main arguer
 Nuno Pedro Moreira Santarém (Master)
Universidade de Aveiro, Portugal
2005 Oxidative stress in Saccharomyces cerevisiae: the key role of Isc1p sphingomyelinase in cell resistance, and the molecular mechanisms associated to the recovery from hydrogen peroxide stress
Supervisor
 Marta Pinheiro Torres Marques (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2005 Identification of genes associated with the control of mitotic progression in Drosophila melanogaster: the role of checkpoint proteins Bub3 and BubR1
Thesis Member
 Carla Sofia da Silva Lopes (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2005 Characterization of DNA lesions in apoptotic Saccharomyces cerevisiae
(Thesis) Main arguer
 Gabriela Filipa Lopes Ribeiro (Master)
Universidade do Minho, Portugal
2004 Towards understanding the prooxidative mechanisms of superoxide dismutase: a mathematical approach
Thesis Member
 Rui Gardner (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2004 Yeast as a model organism to study diseases of protein misfolding
Thesis Member
 Tiago Fleming de Oliveira Outeiro (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2004 Effect of oxidative stress on nucleotide metabolism in Saccharomyces cerevisiae
(Thesis) Main arguer
 Hugo Osório (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2003 Insights into Trip and NOD2 signaling
Thesis Member
 Vasco André Machado de Oliveira (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2003 Study of viral tRNAs encoded by the MHC-68 virus genome
(Thesis) Main arguer
 Paula Fernanda da Silva Gomes (Master)
Universidade de Aveiro, Portugal
2003 Effect of antifungals in biofilm suspensions of Candida albicans and Candida dubliniensis
(Thesis) Main arguer
 Bárbara Cachada Cardoso (Master)
Universidade do Minho, Portugal
2003 Involvement of reactive oxygen species in the mitochondrial apoptotic pathway
(Thesis) Arguer
 Joana Maria do Amaral Campos Gil (Master)
Universidade de Coimbra, Portugal
2001 Biochemical and molecular characterization of yeasts of industrial interest: study of Saccharomyces cerevisiae Bgl2p protein
Thesis Member
 Joaquina Teresa Gaudêncio Dias (PhD)
Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Association member

Society Organization name Role
2017/03 - Current Associação do Instituto de Biologia Molecular e Celular Member
2012 - Current Portuguese Society of Microbiology Member
1991 - Current Portuguese Biochemical Society Member since 1991; Adjunct Secretary of the Supervisory Board (2015-2016); Adjunct Secretary (2017-2018); Vice-President (2019-2022); President (since 2023)
2020/01 - 2022/12/31 FEBS FEBS Ambassador on Education
2008/01 - 2008/12 Groupe polyphenols Member
1999/01 - 2000/12 The Oxygen Society (USA) Member

Committee member

Activity description
Role 		Institution / Organization
2023/01/01 - Current President of SPB Directive Committee
President / Vice-president
 Sociedade Portuguesa de Bioquímica, Portugal
2021/09 - Current Course director of the first degree in Biochemistry
Director
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Universidade do Porto Faculdade de Ciências, Portugal
2018/07 - Current Scientific Committee for the Master's Degree in Environmental Toxicology and Contamination
Member
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2013/07 - Current Scientific Committee of the Doctoral Program in Molecular and Cellular Biology
Member
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/01 - 2023/05 Subdirector of the Molecular Biology Department
Other
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2019/01/01 - 2022/12/31 Vice-President of SPB Directive Committee
President / Vice-president
 Sociedade Portuguesa de Bioquímica, Portugal
2019/11 - 2022/11 Scientific Committee of the "Portuguese Biochemistry Olympiads" (annual)
Member
 Universidade de Coimbra, Portugal
2017/01/01 - 2018/12/31 Adjunct Secretary of SPB Directive Committee
Member
 Sociedade Portuguesa de Bioquímica, Portugal
2018 - 2018 Self-evaluation committee of the 3rd cycle in Molecular and Cellular Biology
Member
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1998/12 - 2009/12 Scientific Council
Member
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1994 - 1997 Assembly of Representatives
Member
 Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal

Conference scientific committee

Conference name Conference host
2017/09 - Current Finance and Policy Committee, International Conference on Yeast Genetics and Molecular Biology
2024/10/24 - 2024/10/26 XXII SPB National Congress of Biochemistry Portuguese Biochemical Society
2024/09/20 - 2024/09/21 XXII Jornadas de Biologia de Leveduras Professor Nicolau van Uden Hotel das Termas da Curia
2023/10/12 - 2023/10/13 SPIB2023 Symposium on pedagogical innovation in biosciences - how to engage students in our practices? Universidade de Aveiro
2023/08/20 - 2023/08/25 31st International Conference on Yeast Genetics and Molecular Biology Florence
2023/04/14 - 2023/04/15 VIII Jornadas da Bioquímica Núcleo de Estudantes de Bioquímica do Porto
2022/04/22 - 2022/04/24 VII Jornadas da Bioquímica Núcleo de Estudantes de Bioquímica do Porto
2021/10/14 - 2021/10/16 XXI SPB - National Congress of Biochemistry Portuguese Biochemical Society
2021/05/07 - 2021/05/09 VI Jornadas da Bioquímica Núcleo de Estudantes de Bioquímica do Porto
2008/10/22 - 2008/10/25 XVI National Congress of Biochemistry Portuguese Biochemical Society
2007/11/28 - 2007/12/01 LINK-AGE Meeting and IBMC Symposium. The free radical theory of ageing - 50 years and beyond: a tribute to Denham Harman Universidade do Porto Instituto de Biologia Molecular e Celular
2005/11/30 - 2005/12/03 Congresso Nacional Micro05 e Biotec05 Portuguese Society of Microbiology
2001/12/13 - 2001/12/15 5th Congress of Free Radicals in Chemistry, Biology and Medicine Universidade do Porto Faculdade de Farmácia

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2018/09 - Current Biochemistry II Bioquímica (Licenciatura) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2018/09 - Current Molecular Signaling Oncologia (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016/09 - Current Biochemistry Medicina Veterinária (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014/01 - Current Course unit "Advanced Training and Seminars Part I" Biologia Molecular e Celular (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2014/01 - Current Curricular unit "Laboratorial Internship" Biologia Molecular e Celular (Doutoramento) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2010/09 - Current Molecular Signaling Bioquímica (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007/09 - Current Biophysics and Biochemistry Ciências do Meio Aquático (Licenciatura) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007/09 - Current Molecular and Cellular Mechanisms of Toxicity and Detoxification Toxicologia e Contaminação Ambientais (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2016 - 2019 Seminar on "Redox Signaling" for students attending the course unit "Signaling and Development" in 2016/17, 2017/18, and 2018/19 Biologia Funcional e Biotecnologia de Plantas (Mestrado integrado) Universidade do Porto Faculdade de Ciências, Portugal
2015 - 2019 Seminar on "Aging in model organisms: yeast" for students attending the course unit "Biogerontology" from 2014/15 to 2018/19 Medicina (Mestrado integrado) Universidade do Porto Faculdade de Medicina, Portugal
2018 - 2018 Seminar on "Oxidative stress and aging: calorie restriction and nutrient signaling" for students attending the course "Radicals, oxidative stress and antioxidants", in 2008-2012, 2014, and 2018 Metabolismo - Clínica e Experimentação (Doutoramento) Universidade do Porto Faculdade de Medicina, Portugal
2007/09 - 2017/09 Complements of Molecular Biology Bioquímica (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/09 - 2016/09 Biochemistry Medicina (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011 - 2016 Seminar on "Redox Signaling" for students attending the course unit "Molecular Cell Physiology" from 2011/12 to 2016/17 Biologia Celular e Molecular (Mestrado integrado) Universidade do Porto Faculdade de Ciências, Portugal
2007/09 - 2015/09 Biochemistry Medicina Veterinária (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2015/05 - 2015/05 Seminar on "Molecular mechanisms associated with type C Niemann-Pick disease" for students attending the course units "Fundamentals of Neuroscience" and "Applied Molecular Biology". Medicina (Mestrado integrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2014 - 2015 Seminar on "Redox Signaling" for students attending the course unit "Oxidative stress and antioxidant defences" in 2013/14, and 2014/15 Biologia Celular e Molecular (Mestrado integrado) Universidade do Porto Faculdade de Ciências, Portugal
2008/09 - 2013/09 Molecular Signaling Bioengenharia (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2007/09 - 2012/09 Biochemistry Medicina (Mestrado integrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2011/05 - 2011/05 Seminar on "Redox signaling and aging: insights from yeast" for students attending the course "Yeast: a valuable research tool" Ciências Farmacêuticas (Doutoramento) Universidade do Porto Faculdade de Farmácia, Portugal
2005/03 - 2005/03 Classes on "Bioenergetics, metabolism and metabolic regulation" (6h) and "Proteomics" (4h) Ensino das Ciências da Terra e da Vida (Mestrado) Universidade da Madeira, Portugal
2004 - 2005 Seminar on "Cellular mechanisms of ageing" for students attending the course unit "Biopathology" in 2004/05 and 2005/06. Medicina (Licenciatura) Universidade do Minho Escola de Medicina, Portugal
2004 - 2005 Practical course “From DNA to protein”, for high school teachers, in 2004 (4h) and 2005 (7h). (Outros) Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2002/05 - 2002/05 Advanced course “Oxidative stress and disease: an advanced practical course”. Laboratory classes (16 h). (Outros) Universidade do Porto Faculdade de Farmácia, Portugal
1996/05 - 1996/06 Advanced course “Oxidative stress and ageing”, Universidade do Porto, Centro de Citologia Experimental. Laboratory classes under the theme “Activity of superoxide dismutases and catalase in yeast” (12 h). (Outros) Universidade do Porto, Portugal
1994/04 - 1994/04 Laboratory classes for students attending the course unit "Oenological Chemistry and Biochemistry" (12h). Viticultura e Enologia (Mestrado) Universidade do Porto Faculdade de Ciências, Portugal
1993/03 - 1993/03 Laboratory Classes of Protein Structure and Function under the theme “Anchoring membrane proteins” (7 h). Imunologia (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
1992/10 - 1992/10 ICRO Advanced course “Molecular response of cells to stress”, Universidade do Porto, Centro de Citologia Experimental. Laboratory classes (20h) (Outros) Universidade do Porto, Portugal

Journal scientific committee

Journal title (ISSN) Publisher
2024/01 - 2024/02 Cells MDPI
2022 - 2023 International Journal of Molecular Sciences MDPI
2022 - 2022 Frontiers in Cell and Developmental Biology (2296-634X)
2022 - 2022 Journal of Applied Microbiology
2008 - 2022 Mechanisms of Ageing and Development (0047-6374) Elsevier
2021 - 2021 FEMS Yeast Research (1567-1364) Oxford University Press
2013 - 2021 Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (1388-1981) Elsevier
2013 - 2020 Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2019 - 2019 FEBS Journal (1742-4658) Wiley (Blackwell Publishing)
2014 - 2019 Microbial Cell (2311-2638) Shared Science Publishers OG
2016 - 2018 Lipids (1558-9307) Wiley (John Wiley & Sons)
2016 - 2018 Molecular Genetics and Genomics (1617-4623) Springer-Verlag
2014 - 2018 Biochimica et Biophysica Acta (BBA) - General Subjects (0304-4165) Elsevier
2017 - 2017 Antonie van Leeuwenhoek (1572-9699) Springer-Verlag
2017 - 2017 Frontiers in Bioscience (1093-4715) Frontiers in BioScience
2017 - 2017 Frontiers in Physiology (1664-042X) Frontiers Media SA
2017 - 2017 Neuroscience Letters (0304-3940) Elsevier
2014 - 2017 Molecular Microbiology (1365-2958) Wiley (Blackwell Publishing)
2016 - 2016 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (0925-4439) Elsevier
2016 - 2016 Current Pharmaceutical Design (1381-6128) Bentham Science
2016 - 2016 Fungal Biology (1878-6146) Elsevier
2013 - 2013 Journal of Bioscience and Bioengineering (1347-4421) Elsevier
2012 - 2012 BMC Microbiology (1471-2180) Springer (Biomed Central Ltd.)
2012 - 2012 Frontiers in Oncology (2234-943X) Frontiers Media SA
2008 - 2011 Journal of Agricultural and Food Chemistry (1520-5118) American Chemical Society
2008 - 2011 PLoS ONE (1932-6203) Public Library of Science
2009 - 2009 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (0167-4889) Elsevier
2009 - 2009 Journal of Proteome Research (1535-3907) American Chemical Society
2007 - 2009 Redox Report (1351-0002) Maney Publishing
2008 - 2008 Cell Biology and Toxicology (1573-6822) Springer-Verlag
2007 - 2007 Archives of Microbiology (1432-072X) Springer-Verlag
2005 - 2005 Comparative Biochemistry and Physiology (0010-406X) Elsevier
2003 - 2003 Microbiology (1608-3237) Pleiades Publishing

Other jury / evaluation

Activity description Institution / Organization
2022 - 2022 Evaluation of 18 PhD projects submitted to FCT Fundação para a Ciência e a Tecnologia, Portugal
2021/07 - 2021/07 Recruitment of an Assistant Professor in the area of Biology. Universidade do Minho Departamento de Biologia, Portugal
2021/05 - 2021/05 Recruitment of two Assistant Professors in the area of Biochemistry. Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2021 - 2021 Evaluation of 9 PhD projects submitted to FCT. Co-coordinator of the panel Experimental Biology and Biochemistry. Fundação para a Ciência e a Tecnologia, Portugal
2020 - 2020 Evaluation of 23 PhD projects submitted to FCT Fundação para a Ciência e a Tecnologia, Portugal
2019 - 2019 Evaluation of 1 project Schweizerischer Nationalfonds zur Förderung der wissenschaftlichen Forschung, Switzerland
2018/07 - 2018/07 Member of the juries for International selection of 3 doctorates hired under Article 23 of Decree-Law No. 57/2016, of 29 August, amended by Law No. 57/2017, of 19 July. Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2018 - 2018 Evaluation of 1 project Alzheimer's Research UK , United Kingdom
2017 - 2017 Evaluation of 1 project Katholieke Universiteit Leuven Onderzoeksraad, Belgium
2015 - 2015 Evaluation of 2 projects Agencia Nacional de Evaluacion y Prospectiva, Spain
2014 - 2014 Evaluation of 1 project Fundação para a Ciência e a Tecnologia, Portugal
2013 - 2014 Evaluation of 2 projects Fonds de la Recherche Scientific, Belgium
2005 - 2011 Evaluation of projects submitted to University of Porto, Program “Scientific research in Pre-graduation", in 2005 (2 projects), 2007 (1 project), 2009 (5 projects), 2010 (1 project) and 2011 (3 projects). Universidade do Porto, Portugal
2010 - 2010 Evaluation of 4 PhD projects submitted to FCT, Programme PROTEC Fundação para a Ciência e a Tecnologia, Portugal
2009 - 2009 Evaluation of projects Fundação para a Ciência e a Tecnologia, Portugal
2007 - 2007 Member of the jury for International selection of 1 researcher in the area of Proteomics Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2006 - 2006 Member of the jury for International selection of 1 researcher in the area of Metabolomics
Distinctions

Award

2022 Best consolidated presentation at the International Congress Microbiologia2022, symposium Microbiology in health
Sociedade Portuguesa de Microbiologia, Portugal
2021 Best oral communication at the XXI Congresso Nacional de Bioquímica (Évora, 14-16/10), Simposium Proteins in Health and Environment
Sociedade Portuguesa de Bioquímica, Portugal
2016 Best poster communication at the XIX Congresso Nacional de Bioquímica
Sociedade Portuguesa de Bioquímica, Portugal
2009 Best poster communication at the MARK-AGE/LINK-AGE joint summer school "From molecular mechanisms to biomarkers of human ageing" (Fréjus, France)