Ana Carolina Dias (2F10-4DE3-123F)

Curriculum Vitae

Ana Carolina Dias

Carolina graduated in Biomedical Sciences from the University of Algarve. Under the supervision of Professor Paula Soares, her BSc thesis focused on validation studies for Uromonitor®, a sensitive urine-based assay used to detect bladder cancer recurrences. Carolina completed her MSc degree in Oncology at the Institute of Biomedical Sciences Abel Salazar, University of Porto. Due to their rare occurrence and lack of in-depth information, her thesis focused on the molecular characterization of a series of upper urinary tract urothelial carcinomas. She is now a third-year PhD student in the Doctoral Program in Biomedicine at the Faculty of Medicine, University of Porto, under the supervision of Dr Sónia Melo. Her PhD project aims to identify novel immune-based strategies to treat PDAC patients by unraveling reprogramming events led by cancer EVs that establish its immunosuppressive microenvironment.

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Identification

Personal identification

Full name: Ana Carolina Dias
Date of birth: 1998/04/24
Gender: Female

Citation names

Dias, Carolina

Author identifiers

Ciência ID: 2F10-4DE3-123F
ORCID iD: 0000-0003-2884-0055

Email addresses

anad@ipatimup.pt (Professional)
acarolinadias@sapo.pt (Personal)

Addresses

Rua Alfredo Allen 208, 4200-135, Porto, Porto, Portugal (Professional)

Websites

https://www.i3s.up.pt/personal-info.php?id=2816&idg=22 (Professional)

Knowledge fields

Medical and Health Sciences - Health Sciences
Medical and Health Sciences - Clinical Medicine - Oncology
Natural sciences - Biological Sciences - Cell Biology
Natural sciences - Biological Sciences - Molecular Biology

Languages

Language	Speaking	Reading	Writing	Listening	Peer-review
Portuguese (Mother tongue)
English	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)	Advanced (C1)
French	Elementary (A2)	Elementary (A2)	Elementary (A2)	Elementary (A2)	Elementary (A2)

Education

	Degree	Classification
2023/05 - 2023/10 Concluded	Introductory Course in Laboratory Animal Science (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/07/17 - 2023/07/20 Concluded	Biostatistics - Linear and Logistic Regression (Outros) Universidade do Porto Faculdade de Medicina, Portugal
2023/05/22 - 2023/05/26 Ongoing	Hands-on course in transgenesis and mutagenesis in zebrafish (Outros) Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/07/16 - 2021/12/09 Concluded	Oncologia (Mestrado) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal "Genetic characterization of upper urinary tract urothelial carcinoma" (THESIS/DISSERTATION)	18
2020/10 - 2020/10/23 Concluded	Writing in the Sciences - online course (Outros) Stanford Medicine, United States Coursera, United States	With Honors
2016/09 - 2019/07/12 Concluded	Ciências Biomédicas (Licenciatura) Universidade do Algarve - Campus de Gambelas, Portugal "Avaliação de biomarcadores genéticos no seguimento de pacientes com cancro da bexiga não-músculo invasor" (THESIS/DISSERTATION)	16
2016/07/11 - 2016/07/15 Concluded	Internship "Cianobactérias no ataque às células cancerígenas" (Outros) CISA - Centro de Investigação em Saúde e Ambiente, Portugal
2015/08/10 - 2015/08/14 Concluded	Internship "As Doenças Genéticas" (Outros) INSA - Instituto Nacional de Saúde Dr. Ricardo Jorge, Portugal

Affiliation

Science

	Category Host institution	Employer
2023/07/01 - 2023/12/31	Researcher (Research)	Fundação para a Ciência e a Tecnologia, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/04/18 - 2023/01/17	Science and Technology Management	Instituto do Emprego e Formação Profissional, Portugal
	U-Monitor, Portugal
2021/03/01 - 2022/04/15	Researcher (Research)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2019/08/12 - 2020/09/30	Researcher (Research)	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
	Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2018/02 - 2018/06	Research Trainee (Research)	Universidade do Algarve Centro de Investigação em Biomedicina, Portugal
	Universidade do Algarve - Campus de Gambelas, Portugal

Projects

Contract

	Designation	Funders
2023/07/01 - 2023/12/31	Decode the EVs Communication Map that Defines the Landscape of CAFs in Pancreatic Cancer 2022.02284.PTDC Research Fellow	Ongoing
2021/03/01 - 2022/04/15	TERT promoter mutations detection in bladder cancer UROEVERIS/2021/1 Research Fellow Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Everis Ongoing
2019/08/12 - 2020/09/30	TERT promoter mutations detection in bladder cancer UROEVERIS Research Fellow Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Everis Concluded

Outputs

Publications

Conference abstract	Ralph M. Wirtz; Elke Veltrup; Hugo Prazeres; Carolina Dias; Roland Hake; Sebastian Eidt; João Vinagre; et al. Corresponding author: Ralph M. Wirtz. "Prospective validation of urine based FGFR screening by Uromonitor within the real-world clinicopathological register trial BRIDGister". Paper presented in 2022 ASCO Genitourinary Cancers Symposium, San Francisco, CA, 2022. Published João Vinagre; Lia Rodrigues; Sule Canberk; Carolina Dias; Sofia Macedo; Paula Soares. Corresponding author: João Vinagre. "DGCR8 microprocessor defect and deregulation of its expression in thyroid tumours". Paper presented in Congresso Português de Endocrinologia - 73ª Reunião Anual da SPEDM, 2022. Published
Journal article	Sara Meireles; Carolina Dias; Diana Martins; Ana Marques; Nuno Dias; Luís Pacheco-Figueiredo; João Silva; et al. "Biomarker Profiling of Upper Tract Urothelial Carcinoma Only and with Synchronous or Metachronous Bladder Cancer". Biomedicines (2024): https://doi.org/10.3390/biomedicines12092154. 10.3390/biomedicines12092154 Bárbara Adem; Nuno Bastos; Carolina F. Ruivo; Sara Sousa Alves; Carolina Dias; Patrícia Vieira; Ines Batista; et al. "Exosomes define a local and systemic communication network in healthy pancreas and pancreatic ductal adenocarcinoma". Nature Communications (2024): http://dx.doi.org/10.1038/s41467-024-45753-7. 10.1038/s41467-024-45753-7 Sara Meireles; Nuno Dias; Diana Martins; Carolina Dias; Marina Gonçalves; João Silva; Carlos Martins Silva; et al. Corresponding author: Sara Meireles. "Prognostic Value of Bladder Involvement in the Outcome of Upper Tract Urothelial Carcinoma". Diagnostics (2023): https://doi.org/10.3390/diagnostics13010153. Published • 10.3390/diagnostics13010153 Rodrigues, Lia; Dias, Carolina; Macedo, Sofia; Batista, Rui; Pestana, Ana; Soares, Paula; Vinagre, João. Corresponding author: Rodrigues, Lia. "DGCR8 microprocessor defect and deregulation of its expression in thyroid cancer". European Journal of Public Health 31 (2021): https://doi.org/10.1093/eurpub/ckab120.001. Published António Castanheira; Maria João Vieira; Mafalda Pinto; Carolina Dias; Luísa Prada; Sofia Macedo; Margarida Sá Fernandes; et al. Corresponding author: Paula Boaventura. "TERTp mutations and p53 expression in head and neck cutaneous basal cell carcinomas with different aggressive features". Scientific Reports 11 1 (2021): http://dx.doi.org/10.1038/s41598-021-89906-w. Published • 10.1038/s41598-021-89906-w
Thesis / Dissertation	"Genetic characterization of upper urinary tract urothelial carcinoma". Master, Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, 2021.

Activities

Oral presentation

	Presentation title	Event name Host (Event location)
2023/10/25	Modulation of PDAC immune response through cancer EVs" in "MOVE - Mobility for Vesicles Research in Europe	MOVE - Mobility for Vesicles Research in Europe - 1st edition (Malaga, Spain)
2023/05/11	Evaluation of RRAS2 and TTP1 Promoter Mutations in Thyroid Tumours	IJUP23 - 16º Encontro de Investigação Jovem da Universidade do Porto Universidade do Porto (Porto, Portugal)
2023/05/11	Understanding the genetics of UTUC and its implications	29th Porto Cancer Meeting Instituto de Investigação e Inovação em Saúde da Universidade do Porto (Porto, Portugal)
2022/10/05	Uromonitor as a Potential Predictive Test in BCG Treated Bladder Cancer Patients	XXXV Reunión Nacional del Grupo de Urología Oncológica AEU - Asociación Española de Urología (Castellón de La Plana, Spain)
2021/05/05	Genetic characterization of upper urinary tract urothelial carcinoma	IJUP21 - 14º Encontro de Investigação Jovem da Universidade do Porto Universidade do Porto (Porto, Portugal)
2021/05/05	Characterization of DGCR8 microprocessor defect in thyroid lesions	IJUP21 - 14º Encontro de Investigação Jovem da Universidade do Porto Universidade do Porto (Porto, Portugal)
2021/02/22	Genetic characterization of upper urinary tract urothelial carcinoma	5th SYMPOSIUM OF THE MSc IN ONCOLOGY ICBAS, Universidade do Porto and IPO-Porto (Porto, Portugal)

Event participation

	Activity description Type of event	Event name Institution / Organization
2019/03/13 - 2019/03/16	"X Jornadas Nacionais de Ciências Biomédicas" Congress	X Jornadas Nacionais de Ciências Biomédicas Universidade de Aveiro, Portugal
2017/03/08 - 2017/03/11	"VIII Jornadas Nacionais de Ciências Biomédicas" Congress	VIII Jornadas Nacionais de Ciências Biomédicas Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2016/11/24 - 2016/11/24	"1ª Jornada ALGARVE BIOMEDICAL CENTER" Conference	1ª Jornadas ALGARVE BIOMEDICAL CENTER Centro Hospitalar do Algarve EPE, Portugal
2016/11/10 - 2016/11/10	"V Simpósio de Ciências Biomédicas" Symposium	V Simpósio de Ciências Biomédicas Universidade do Algarve, Portugal
2016/01 - 2016/05	"XI Olimpíadas de Biotecnologia" Other	XI Olimpíadas de Biotecnologia Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal Sociedade Portuguesa de Biotecnologia, Portugal
2016/01/06 - 2016/01/06	"1ª Eliminatória das Olimpíadas Portuguesas de Biologia Sénior" Other	1ª Eliminatória das Olimpíadas Portuguesas de Biologia Sénior Ciência Viva, Portugal
2015/01 - 2015/05	"X Olimpíadas de Biotecnologia" Other	X Olimpíadas de Biotecnologia Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal Sociedade Portuguesa de Biotecnologia, Portugal
2013/11/26 - 2013/11/26	Lecture by Prof. Dr. Kim Larsen Seminar	"Sistemática e Taxonomia" Escola S/3 Arquitecto Oliveira Ferreira, Portugal

Association member

	Society Organization name	Role
2023/06 - Current	PNEV - Portuguese Network on Extracellular Vesicles

Committee member

	Activity description Role	Institution / Organization
2018/01 - 2018/12	Member of "Mesa do Plenário" representing BSc students of Biomedical Sciences	Universidade do Algarve, Portugal
2018 - 2018	Member of the organization committee for the "IX Jornadas Nacionais de Ciências Biomédicas"	Universidade do Algarve, Portugal

Distinctions

Other distinction

2023	2023 Call for PhD Studentships Fundação para a Ciência e a Tecnologia, Portugal
2022	Estágio Ativar.pt Instituto do Emprego e Formação Profissional, Portugal