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Dr. Christiane L. Salgado (female) is currently an Assistant researcher at INEB/i3S into Bioengineered 3D Microenvironment group. With a background of Dental Medicine (Brazil), a master degree in Sciences (Specialized in human physiology and pharmacology) and a PhD in Mechanical Engineering (Materials and Process) at State University of Campinas (Brazil) in 2009. By using tissue engineering strategies , she aims at providing an in situ required biological signals to promote vascular and bone tissue regeneration at maxilofacial critical bone defects. The research on new biomaterials for application in dental medicine and orthopedics includes the development of new polymers for efficient cells spheroids or cell products delivery and preparation of bone grafts for large bone defects treatment, including neovascularization and neuronal repair strategies to inosculate the implant at the host tissue. Societal and ethical issues that concern Regenerative Medicine and Tissue Engineering are also topics in which she is involved. She has also been engaged in technology transfer projects including the development of an industrial prototype in collaboration with the Portuguese company Arthur Salgado. Recently, she focuses on the study of dental MSCs as a tool to promote bone formation with collaboration of Universidade Católica Portuguesa (Faculty of Dental Medicine). She collaborated with Prof. Herman Mansur (UFMG, Brazil) on the development of nanophotonics particles (Quantum dots) to track MSCs by bioimaging approach with in vivo real-time imaging analysis. To this date, she was successful in establishing national and international collaborations with outstanding researchers in their fields that resulted in high impact publications and 3 awards. She has published 26 articles in peer reviewed international journals and 1 book chapters with more than 557 citations (h index = 13). Has 2 patents registered. She was researcher into 5 concluded projects (3 national, 1 European and 1 U.S.A.) and PI of 2 national projects. She had supervised several master students in Biomedical Engineering and Dental Medicine; and a PhD student in Biomedical Engineering. She helped to organize 5 scientific events. She is also involved on educational activities, lab management, Greenlab initiatives and science dissemination strategies.
Identification

Personal identification

Full name
Christiane Laranjo Salgado

Citation names

  • Salgado, Christiane

Author identifiers

Ciência ID
2713-8B17-634C
ORCID iD
0000-0002-3844-1667

Email addresses

  • christianesalgado@gmail.com (Personal)

Telephones

Telephone
  • 226074900 (Professional)

Addresses

  • Rua Alfredo Allen, 208, 4200-135, Porto, Porto, Portugal (Professional)

Knowledge fields

  • Medical and Health Sciences - Medical Biotechnology - Biomaterials
  • Medical and Health Sciences - Medical Biotechnology - Health-Related Biotechnology

Languages

Language Speaking Reading Writing Listening Peer-review
English Advanced (C1) Advanced (C1) Advanced (C1) Advanced (C1)
Spanish; Castilian Intermediate (B1) Advanced (C1) Intermediate (B1) Intermediate (B1)
French Beginner (A1) Intermediate (B1) Beginner (A1) Beginner (A1)
Education
Degree Classification
2010/12/01 - 2018/10/31
Concluded
Novel Modified Collagen/ Hydroxyapatite nanoparticles composites (Coll/nanoHA) with SIBLING proteins for bone regeneration (Pós-doutoramento)
Major in Pós-doutoramento em Engenharia Biomédica
Instituto Nacional de Engenharia Biomédica, Portugal

Universidade do Porto Faculdade de Engenharia, Portugal
2009/08/01 - 2010/07/31
Concluded
Postdoc in Chemical Engineering (Postgraduate Certificate)
Universidade Estadual de Campinas Faculdade de Engenharia Química, Brazil
"Development, Characterization and Cytotoxicity of Chitosan and Polycaprolactone Membranes for Application in Tissue Engineering" (THESIS/DISSERTATION)
Approved
2009
Concluded
PhD in Mechanical Engineering (Materials and Processing) (Doctor)
Universidade Estadual de Campinas Faculdade de Engenharia Mecânica, Brazil
"Development of Polymeric Matrices for Bone Tissue Engineering" (THESIS/DISSERTATION)
Approved
2005
Concluded
Master in Science (Physiology and Pharmacology) (Master)
Universidade Federal de Minas Gerais Instituto de Ciências Biológicas, Brazil
"Biocompatibility Evaluation of Active Porous Bioglass - BG60S" (THESIS/DISSERTATION)
Approved
2001
Concluded
Licence in Dental Medicine (Licence)
Universidade Federal de Minas Gerais, Brazil
"-" (THESIS/DISSERTATION)
16,5
Affiliation

Science

Category
Host institution
Employer
2021/01/01 - Current Research Assistant (Research) Instituto Nacional de Engenharia Biomédica, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
(...)
2018/11/01 - 2020/12/31 Contracted Researcher (Research) Instituto Nacional de Engenharia Biomédica, Portugal
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
(...)
2010/12/01 - 2018/10/30 Postdoc (Research) Instituto Nacional de Engenharia Biomédica, Portugal

Teaching in Higher Education

Category
Host institution
Employer
2014/09/01 - 2018/07/31 Assistant Professor (University Teacher) Universidade Católica Portuguesa Centro Regional de Viseu, Portugal
2012/09/01 - 2014/02/28 Assistant Professor (University Teacher) Universidade do Porto Faculdade de Engenharia, Portugal

Positions / Appointments

Category
Host institution
Employer
2014/09/01 - 2015/07/31 Scientific/technical-scientific council or corresponding body Universidade Católica Portuguesa Centro Regional de Viseu, Portugal
Projects

Grant

Designation Funders
2024/01/01 - 2025/12/31 BioMade4U - Bioengineering living materials for personalized treatment of osteoradionecrosis patients
0000
Principal investigator
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Fundação Amélia de Mello
Ongoing
2022/01/01 - 2025/07/31 Angiogenesis in silico: from numerical simulation to tissue engineering application
PTDC/EME-APL/3058/2021
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal

Instituto de Ciência e Inovação em Engenharia Mecânica e Engenharia, Portugal
Associação para a Inovação e Desenvolvimento da FCT
Ongoing
2022/06/01 - 2022/12/31 Greening up Life Sciences Laboratories - GO4GREENLAB
EUGLOH
Researcher
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
Concluded

Contract

Designation Funders
2013 - 2017 New Generation Biomimetic and Customized Implants for Bone Engineering - COSTAction NEWGEN
COST MP1301
Researcher
Instituto Nacional de Engenharia Biomédica, Portugal
Concluded
2010/12/01 - 2013/02/28 Development of New Products Based on Hydroxyapatite Materials (HA) - NANOFORBONE
NORTE-07-0202-FEDER-005372
Researcher
Universidade do Porto Faculdade de Engenharia, Portugal

Instituto Nacional de Engenharia Biomédica, Portugal
Concluded

Other

Designation Funders
2017/11/01 - 2019/10/30 Innovative Devices for Bone Regeneration - COLYBRID
NORTE-01-0247-FEDER-023345
Researcher
Concluded
2018/02/01 - 2018/07/31 In vitro degradation, mechanical and morphological characterization of a novel pre-hydrated collagen membrane of bovine origin - Project Dentsply Sirona Implants
I-BI-17-030
Principal investigator
Universidade Católica Portuguesa Centro Regional de Viseu, Portugal
Concluded
2011/12/01 - 2013/01/31 Development of scaffolds based on nanohydroxyapatyte for bone application with drug delivery for bacterial infection - NanoBiofilm
PTDC/SAU-BMA/111233/2009
Researcher
Concluded
Outputs

Publications

Book
  1. Salgado, C.L.; Solomão, Z.; Silva, P.B.; Sanchez, E.M.S.; Zavaglia, C.A.C.. Biocompatibility and osteo-differentiation study of poly (e-caprolactone) and ß-tricalcium phosphate composite membranes. 2009.
    10.4028/0-87849-353-0.399
Conference abstract
  1. Guerra, Ana; Belinha, Jorge; Salgado, Christiane; Monteiro, Fernando Jorge; Natal Jorge, Renato. "Simulating VEGF-Driven Capillary Network Formation: A Meshless Method Study". Paper presented in CMN 2024, Aveiro, 2024.
  2. Guerra, Ana; Belinha, Jorge; Salgado, Christiane; Fernando Jorge Monteiro; Natal Jorge, Renato. "Computational Insights of Compression in VEGF Diffusion and Capillary Network Formation". Paper presented in 29th Congress of the European Society of Biomechanics, Edinburgh, 2024.
  3. Shet, Sudhakar. "In vitro biocompatibility and in vivo antibacterial effect of nanohydroxyapatite and zinc oxide granules (nanoHA/ZnO)". Paper presented in 4th International Symposium on Surfaces and Interfaces for Biomaterials (eCM Conference), Roma, 2013.
    Accepted
  4. Salgado, Christiane. "Superhydrophobic patterned chips for the combinatorial and rapid study of 3D biomaterials-cells interactions and protein delivery systems". Paper presented in 3rd TERMIS World Congress, Viena, 2012.
    Accepted
  5. Salgado, Christiane. "Patterned superhydrophobic surfaces for the combinatorial assessment of 3D biomaterials-cells interactions. Journal of Tissue Engineering and Regenerative Medicine". Paper presented in 3rd TERMIS World Congress, Viena, 2012.
    Accepted
  6. Salgado, Christiane. "Superhydrophobic platforms for the combinatorial analysis of biomaterials-cells interactions using arrays of 3D scaffolds with distinct mechanical and morphological properties". Paper presented in 3rd TERMIS World Congress, Viena, 2012.
    Accepted
  7. Salgado, Christiane. "Combinatorial Cell-Porous Scaffolds Interactions Study and Scaffold Physicochemical Characterization in an Innovative Bioinspired High-Throughput Platform". Paper presented in 4th Joint ESAO-IFAO Congress 2011 – XXXVIII Congress of the European Society for Artificial Organs (ESAO 2011), Porto, 2011.
    Accepted
  8. Salgado, Christiane. "Innovative three-dimensional platform for combinatorial analysis of cell/biomaterials interactions". Paper presented in TERMIS EU 2011 Annual Meeting, Granada, 2011.
    Accepted
  9. Salgado, Christiane. "Preparation of Collagen-Hydroxyapatite Biocomposite Scaffolds By Cryogelation Method For Tissue Engineering Applications". Paper presented in TERMIS EU 2011 Annual Meeting, Granada, 2011.
    Accepted
Conference paper
  1. Guerra, Ana; Belinha, Jorge; Salgado, Christiane; Monteiro, Ferando Jorge; Jorge, Renato Natal. "Compressive loading affects endothelial cell migration: a numerical study". Paper presented in 7th IEEE Portuguese Meeting on Bioengineering, Porto, 2023.
    10.1109/enbeng58165.2023.10175357
Conference poster
  1. Ribeiro, João S.; Ana Guerra; Natal Jorge, Renato; Fernando Jorge Monteiro; Barrias, Cristina; Salgado, Christiane. Corresponding author: Salgado, Christiane. "Mechanical regulation of angiogenesis: towards improved therapeutic tissue engineering". Paper presented in The 11th i3S Annual Meeting, 2024.
  2. Costa, Ana Catarina ; Salgado, Christiane. Corresponding author: Salgado, Christiane. "Development of a personalised 3D bioconstruct for oral maxillofacial critical bone defect application". Paper presented in 32nd Annual Conference of the European Society of Biomaterials - ESB 2022, 2022.
  3. Salgado, Christiane; Barrias, Cristina; Fernando Jorge Monteiro. Corresponding author: Salgado, Christiane. "Dental MSC spheroids: development of a pre-clinical imaging model to clarify cell behavior in vivo.". Paper presented in 31st Annual Conference of the European Society for Biomaterials (ESB 2021), 2021.
  4. Fernandes, Maria Helena; Mariana Souto-Lopes; Fernando Jorge Monteiro; Salgado, Christiane. Corresponding author: Mariana Souto-Lopes. "Characterization Of The Microstructure, Mechanical Features And Biocompatibility Of A Ready-to-use Nano-Hydroxyapatite/Chitosan Biodegradable Scaffold For Periodontal Bone Regeneration". Paper presented in 31st Annual Conference of the European Society for Biomaterials (ESB 2021), 2021.
  5. Salgado, Christiane. "Translational research for the development of a biomedical device based on collagen and nanohydroxyapatite". Paper presented in 11th World Biomaterials Congress, 2020.
  6. Salgado, Christiane. "Sterility and cytocompatibility of a nanohydroxyapatite/chitosan composite for bone regeneration". Paper presented in XXV Congresso da Ordem dos Médicos Dentistas, Matosinhos, 2016.
  7. Salgado, Christiane. "Sterility and cytocompatibility of a nanohydroxyapatite/chitosan composite for bone regeneration". Paper presented in XXIV Congresso da Ordem dos Médicos Dentistas, 2015.
  8. Salgado, Christiane. "Fluorescent Bionanoprobes based on Quantum dot-Chitosan-O-Phospho-L-serine Conjugates for Labeling Human Bone Marrow Stromal Cells". Paper presented in 4th International Symposium in Applied Bioimaging (BioImaging2015), 2015.
  9. Salgado, Christiane. "Combinatorial Cell-Porous Scaffolds Interactions Study and Scaffold Physicochemical Characterization in an Innovative Bioinspired High-Throughput Platform". Paper presented in XXXVIII Congress of the European Society for Artificial Organs (ESAO), 2011.
  10. Salgado, Christiane. "Preparation of Collagen-Hydroxyapatite Biocomposite Scaffolds by Cryogelation Method for Tissue Engineering Applications". Paper presented in TERMIS EU 2011 Annual Meeting, 2011.
  11. Salgado, Christiane. "Characterization of Degradation and Biocompatibility of Chitosan and Polycaprolactone Membranes for Application in Tissue Engineering". Paper presented in XVIII Congresso Brasileiro De Engenharia Química (COBEQ), 2010.
  12. Salgado, Christiane. "Morphology and biocompatibility analyses of chitosan and polycaprolactone membranes for tissue engineering application". Paper presented in 19th International Congress of Chemical and Process Engineering (CHISA 2010), 2010.
  13. Salgado, Christiane. "Evaluation of Polycaprolactone and Sebacic Acid Blends Fused for Bone Tissue Engineering". Paper presented in 8th World Biomaterials Congress, 2008.
  14. Salgado, Christiane. "Injectable Polymeric Matrices for Bone Tissue Engineering". Paper presented in 8th World Biomaterial Congress, 2008.
  15. Salgado, Christiane. "Evaluation of Polycaprolactone and Sebacic Acid Blend Scaffolds for Bone Tissue Engineering". Paper presented in 5th Congresso Latino-Americano de Orgãos Artificiais e Biomateriais · COLAOB 2008, 2008.
  16. Salgado, Christiane. "Comparison between two orthopedic cements based on poly methyl methacrylate (PMMA) according to some requirements of ABNT NBR-ISO 5833". Paper presented in 9º Congresso Brasileiro de Polímeros (ABPOL), 2007.
  17. Salgado, Christiane. "Evaluation of Polycaprolactone and Sebacic Acid Blends Fused for Bone Tissue Engineering". Paper presented in Euromat 2007 - European Congress on Advanced Materials and Processes, 2007.
  18. Salgado, Christiane. "Morphological and Mechanical Evaluation of Polyamides used in Rapid Prototyping after Accelerated Aging". Paper presented in Polychar15 - World Forum on Advanced Materials, 2007.
  19. Salgado, Christiane. "Mechanical Evaluation of Polyamides Used in Rapid Prototyping after Accelerated Aging". Paper presented in 3rd China-Europe Symposium - Processing and Properties of Reinforced Polymers, 2007.
  20. Salgado, Christiane. "Evaluation of Mechanical Properties of Polyamides Used In Rapid Prototyping". Paper presented in V Encontro SBPMat, 2006.
  21. Salgado, Christiane. "Bioreabsorbable Polymer Degradation for Controlled Drug Release". Paper presented in IV Congresso Latino Americano de Órgãos Artificiais E Biomateriais, 2006.
  22. Salgado, Christiane. "Citotoxity and Inflammatory Evaluation of Porous Bioactive Glass Scaffolds". Paper presented in IV Encontro da SBPMat, 2005.
Journal article
  1. Salgado, Christiane; Barrias, Cristina. Corresponding author: Salgado, Christiane. "Bridging the Gap Between In Vitro Models and In Vivo Vascularization: Mechanical regulation of angiogenesis". Angiogenesis (2025):
    Submitted
  2. Salgado, Christiane. "Editorial Research Topic: The Expanding Frontiers of Stem Cells Therapy in Oral Maxillo-Facial Tissue Engineering and Regenerative Medicine". Front. Bioeng. Biotechnol. - Biomaterials (2025): https://doi.org/10.3389/fbioe.2025.1548950.
    Published
  3. Salgado, Christiane. "Bridging the Gap Between In Vitro Models and In Vivo Vascularization: Mechanical regulation of angiogenesis". Materias today Bio (2024):
    Submitted
  4. Sahar Jafari Nivlouei; Ana Guerra; Jorge Belinha; Naside Mangir; Sheila MacNeil; Christiane Salgado; Fernando Jorge Monteiro; Renato Natal Jorge. "Angiogenesis Dynamics: A Computational Model of Intravascular Flow Within a Structural Adaptive Vascular Network". Biomedicines (2024): https://doi.org/10.3390/biomedicines12122845.
    10.3390/biomedicines12122845
  5. Souto-Lopes, M.; Grenho, L.; Manrique, Y.; Dias, M. M.; Lopes, J. C. B.; Fernandes, M. H.; Monteiro, F. J.; Salgado, C. L.. "Bone regeneration driven by a nano-hydroxyapatite/chitosan composite bioaerogel for periodontal regeneration". Frontiers in Bioengineering and Biotechnology 12 (2024): http://dx.doi.org/10.3389/fbioe.2024.1355950.
    Open access • 10.3389/fbioe.2024.1355950
  6. Guerra, A.C.; Belinha, J.; Salgado, C. L.; Monteiro, F.J.; Natal Jorge, R.. "Computational Insights into the Interplay of Mechanical Forces in Angiogenesis". Biomedicines 12 (2024): 1045. https://www.mdpi.com/2227-9059/12/5/1045.
    Published
  7. Ana Guerra; Jorge Belinha; Christiane Salgado; Fernando Jorge Monteiro; Renato Natal Jorge. "Computational Insights into the Interplay of Mechanical Forces in Angiogenesis". Biomedicines (2024): https://doi.org/10.3390/biomedicines12051045.
    10.3390/biomedicines12051045
  8. Mariana Pereira; Jéssica Pinto; Belén Arteaga; Ana Guerra; Renato Natal Jorge; Fernando Jorge Monteiro; Christiane Laranjo Salgado. "A Comprehensive Look at In Vitro Angiogenesis Image Analysis Software". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms242417625.
    10.3390/ijms242417625
  9. Mariana Souto-Lopes; Maria Helena Fernandes; Fernando Jorge Monteiro; Christiane Laranjo Salgado. "Bioengineering Composite Aerogel-Based Scaffolds That Influence Porous Microstructure, Mechanical Properties and In Vivo Regeneration for Bone Tissue Application". Materials (2023): https://doi.org/10.3390/ma16124483.
    10.3390/ma16124483
  10. Salgado, Christiane. Corresponding author: Salgado, Christiane. "Bioengineering composite aerogel-based scaffolds that influence the porous microstructure, mechanical properties and in vivo regeneration for bone tissue application". Materials 16 12 (2023): 4483. https://doi.org/10.3390/ma16124483.
    Open access • Published
  11. Souto-Lopes, Mariana; Grenho, Liliana; Manrique, Yaidelin; Dias, Madalena Maria; Fernandes, Maria Helena; Monteiro, Fernando Jorge; Salgado, Christiane Laranjo. Corresponding author: Salgado, Christiane Laranjo. "Full physicochemical and biocompatibility characterization of a supercritical CO2 sterilized nano-hydroxyapatite/chitosan biodegradable scaffold for periodontal bone regeneration". Biomaterials Advances (2023): 213280. http://dx.doi.org/10.1016/j.bioadv.2023.213280.
    10.1016/j.bioadv.2023.213280
  12. Ana Catarina Costa; Patrícia Mafalda Alves; F.J.Monteiro; CL Salgado. "Interactions between Dental MSCs and Biomimetic Composite Scaffold during Bone Remodeling Followed by In Vivo Real-Time Bioimaging". International Journal of Molecular Sciences 24 3 (2023): 1827. https://www.mdpi.com/1422-0067/24/3/1827.
    Published • 10.3390/ijms24031827
  13. Salgado, Christiane. "Bioengineered Fluorescent Nanoprobe Conjugates for Tracking Human Bone Cells: In Vitro Biocompatibility Analysis". Materials 14 16 (2021): 4422-4422. http://dx.doi.org/10.3390/ma14164422.
    10.3390/ma14164422
  14. Salgado, Christiane. "Translational Research for Orthopedic Bone Graft Development". Materials 14 15 (2021): 4130-4130. http://dx.doi.org/10.3390/ma14154130.
    10.3390/ma14154130
  15. Salgado, Christiane L.; Barrias, Cristina C.; Monteiro, Fernando J. M.. "Clarifying the Tooth-Derived Stem Cells Behavior in a 3D Biomimetic Scaffold for Bone Tissue Engineering Applications". Frontiers in Bioengineering and Biotechnology 8 (2020): http://dx.doi.org/10.3389/fbioe.2020.00724.
    10.3389/fbioe.2020.00724
  16. Salgado, Christiane. "Biomimetic Composite Scaffold With Phosphoserine Signaling for Bone Tissue Engineering Application". Frontiers in Bioengineering and Biotechnology (2019): http://dx.doi.org/10.3389/fbioe.2019.00206.
    10.3389/fbioe.2019.00206
  17. Ruphuy, G.; Souto-Lopes, M.; Paiva, D.; Costa, P.; Rodrigues, A. E.; Monteiro, F. J.; Salgado, C. L.; et al. "Supercritical CO 2 assisted process for the production of high-purity and sterile nano-hydroxyapatite/chitosan hybrid scaffolds". Journal of Biomedical Materials Research Part B: Applied Biomaterials 106 3 (2017): 965-975. http://dx.doi.org/10.1002/jbm.b.33903.
    10.1002/jbm.b.33903
  18. Grenho, L; Salgado, C L; Fernandes, M H; Monteiro, F J; Ferraz, M P. "Antibacterial activity and biocompatibility of three-dimensional nanostructured porous granules of hydroxyapatite and zinc oxide nanoparticles—anin vitroandin vivostudy". Nanotechnology 26 31 (2015): 315101. http://dx.doi.org/10.1088/0957-4484/26/31/315101.
    10.1088/0957-4484/26/31/315101
  19. Salgado CL; Grenho L; Fernandes MH; Colaço BJ; Monteiro FJ. "Biodegradation, biocompatibility and Osteoconduction Evaluation of Collagen-NanoHydroxyapatite Cryogels for Bone Tissue Regeneration.". (2015): http://europepmc.org/abstract/med/26179958.
    10.1002/jbm.a.35540
  20. Salgado, Christiane L.; Mansur, Alexandra A. P.; Mansur, Herman S.; Monteiro, Fernando J. M.. "Fluorescent bionanoprobes based on quantum dot-chitosan–O-phospho-l-serine conjugates for labeling human bone marrow stromal cells". RSC Adv. 4 90 (2014): 49016-49027. http://dx.doi.org/10.1039/c4ra08247h.
    10.1039/c4ra08247h
  21. Grenho, L.; Salgado, C.L.; Fernandes, M.H.; Monteiro, F.J.; Ferraz, M.P.. "In vitro biocompatibility and in vivo antibacterial effect of nanohydroxyapatite and zinc oxide granules (nanoHA/ZnO)". European Cells and Materials 26 SUPPL.6 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84892529070&partnerID=MN8TOARS.
  22. Rodrigues, S.C.; Salgado, C.L.; Sahu, A.; Garcia, M.P.; Fernandes, M.H.; Monteiro, F.J.. "Preparation and characterization of collagen-nanohydroxyapatite biocomposite scaffolds by cryogelation method for bone tissue engineering applications". Journal of Biomedical Materials Research - Part A 101 A 4 (2013): 1080-1094. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876183449&partnerID=MN8TOARS.
    10.1002/jbm.a.34394
  23. Oliveira, Mariana B.; Salgado, Christiane L.; Song, Wenlong; Mano, João F.. "Combinatorial On-Chip Study of Miniaturized 3D Porous Scaffolds Using a Patterned Superhydrophobic Platform". Small 9 5 (2012): 768-778. http://dx.doi.org/10.1002/smll.201201436.
    10.1002/smll.201201436
  24. Salgado, Christiane L.; Sanchez, Elisabete M.S.; Zavaglia, Cecília A.C.; Almeida, Ana Beatriz; Granja, Pedro L.. "Injectable Biodegradable Polycaprolactone–Sebacic Acid Gels for Bone Tissue Engineering". Tissue Engineering Part A 18 1-2 (2012): 137-146. http://dx.doi.org/10.1089/ten.tea.2011.0294.
    10.1089/ten.tea.2011.0294
  25. Salgado, Christiane L.; Oliveira, Mariana B.; Mano, João F.. "Combinatorial cell–3D biomaterials cytocompatibility screening for tissue engineering using bioinspired superhydrophobic substrates". Integrative Biology 4 3 (2012): 318. http://dx.doi.org/10.1039/c2ib00170e.
    10.1039/c2ib00170e
  26. Salgado, C.L.; Sanchez, E.M.S.; Zavaglia, C.A.C.; Granja, P.L.. "Biocompatibility and biodegradation of polycaprolactone-sebacic acid blended gels". Journal of Biomedical Materials Research - Part A 100 A 1 (2012): 243-251. http://www.scopus.com/inward/record.url?eid=2-s2.0-81955165189&partnerID=MN8TOARS.
    10.1002/jbm.a.33272
  27. Salgado, C. L.; Sanchez, E. M. S.; Mano, J. F.; Moraes, A. M.. "Characterization of chitosan and polycaprolactone membranes designed for wound repair application". Journal of Materials Science 47 2 (2011): 659-667. http://dx.doi.org/10.1007/s10853-011-5836-6.
    10.1007/s10853-011-5836-6
  28. Salgado, C.; Sanchez, E.; Zavaglia, C.; Granja, P.L.. "Injectable polymeric matrices for bone tissue engineering". 8th World Biomaterials Congress 2008 2 (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-84869029385&partnerID=MN8TOARS.
  29. Salgado, C.; Sanchez, E.; Zavaglia, C.. "Evaluation of polycaprolactone and sebacic acid blends fused for bone tissue engineering". 8th World Biomaterials Congress 2008 3 (2008): http://www.scopus.com/inward/record.url?eid=2-s2.0-84869070773&partnerID=MN8TOARS.
  30. Salgado, C.L.; Sanchez, E.M.S.; Zavaglia, C.A.C.; Oliveira, M.F.; Silva, J.V.L.. "Evaluation of degradation of bioabsorbable polycaprolactone used in rapid prototyping for medical application". Proceedings of the 3rd International Conference on Advanced Research in Virtual and Rapid Prototyping: Virtual and Rapid Manufacturing Advanced Research Virtual and Rapid Prototyping (2007): 101-105. http://www.scopus.com/inward/record.url?eid=2-s2.0-75049085879&partnerID=MN8TOARS.
  31. Salgado, C.L.; Turchetti-Maia, R.M.M.; Pereira, M.M.; Salas, C.E.; Francischi, J.N.; Lopes, M.T.P.. "Evaluation of biocompatibility for porous bioactive glass scaffolds". Key Engineering Materials 309-311 II (2006): 1035-1038. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645328287&partnerID=MN8TOARS.

Intellectual property

Patent
  1. Salgado, Christiane. 2010. "Preparation method of injectable biodegradable polymer".
    Granted/Issued
  2. Salgado, Christiane. 2010. "Preparation method of injectable biodegradable polymer". Brazil.
    Granted/Issued
Activities

Oral presentation

Presentation title Event name
Host (Event location)
2024/09/16 The Impact of Biomechanical Stimulus and Support Cells (MSCs) on Angiogenesis 8th China-Europe Symposium on Biomaterials in Regenerative Medicine (CESB2024)
European Society of Biomaterials /Chinese Society of Biomaterials (Nuremberg, Germany)
2022/09/16 Design of 3D bioengineered personalized scaffolds to potentiate bone ingrowth and angiogenic network for oral tissues reconstruction 2nd Edition of International Conference on Tissue Engineering and Regenerative Medicine
Magnus Conference (Paris, France)
2019/10/18 Development of bioengineering solutions for bone regeneration XXIX Congresso Anual SPEMD
SPEMD - Sociedade Portuguesa de Estomatologia e Medicina Dentária (porto, Portugal)
2019/06/27 Clarifying interplay between dental MSC and biomimetic material with real-time in vivo imaging model Interrogations at the Biointerface – 7th Advanced Summer School
i3S - Instituto de Investigação e Inovação em Saúde/Universidade do Porto (Porto, Portugal)
2017/05/21 Osteoinduction Evaluation of Collagen-NanoHydroxyapatite Cryogels with Phosphoserine for Bone Tissue Regeneration 6th China-Europe Symposium on Biomaterials in Regenerative Medicine (CESB2017)
European Society for Biomaterials, Chinese Society for Biomaterials, Instituto de Engenharia Biomédica, i3S – Instituto de Investigação e Inovação em Saúde (porto, Portugal)
2013/09/24 In vitro biocompatibility and in vivo antibacterial effect of nanohydroxyapatite and zinc oxide granules (nanoHA/ZnO) 4th International Symposium on Surface and Interface Biomaterials
European Society of Cells and Materials (Roma, Italy)
2012/06/01 High-throughput physicochemical characterization and biological assessment of 3D porous scaffolds using a patterned superhydrophobic platform 9th World Biomaterials Congress
Chinese Society for Biomaterials (Chegdu, China)
2011 Innovative three-dimensional platform for combinatorial analysis of cell/biomaterials interactions. TERMIS EU 2011 Annual Meeting
Tissue Engineering and Regenerative Medicine International Society (TERMIS) (Granada, Spain)
2008/10/01 Biocompatibility and Osteo-Differentiation Study of Poly(E-Caprolactone) and ß-Tricalcium Phosphate Composite Membranes Bioceramics 20 - 20th Annual Meeting of the International Society for Ceramics in Medicine
International Society for Ceramics in Medicine (Búzios, Brazil)
2007/10/01 Evaluation of Degradation of Bioabsorbable Polycaprolactone Used in Rapid Prototyping for Medical Application 3rd International Conference On Advanced Research In Virtual And Rapid Prototyping (VRAP)
Instituto Politécnico de Leiria (IPL) (Leiria, Portugal)
2004/07/27 Determination of cytotoxicity and acute inflammatory response induced by porous active bioglass III Congresso latino-americano de Biomateriais e Órgãos Artificiais
Sociedade Latino Americana de Biomateriais (Slabo) (Campinas, Brazil)

Supervision

Thesis Title
Role
Degree Subject (Type)
Institution / Organization
2024/09/15 - 2025/07/31 Understanding the influence of shear stress and support cells (MSC) to engineer vascularized units for tissue engineering applications
Supervisor
Engenharia Biomédica (Master)
Instituto Politécnico do Porto Instituto Superior de Engenharia do Porto, Portugal
2024/07/01 - 2024/12/31 Bridging the Gap Between In Vitro Models and In Vivo Vascularization: Mechanical regulation of angiogenesis
Supervisor
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2023/05/17 - 2024/05/15 A Comprehensive Evaluation at Angiogenesis with Image Analysis Software
Supervisor
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/03/17 - 2023/03/15 Effect of shear stress on angiogenesis physiology in tissue engineering
Supervisor
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2022/04/01 - 2022/09/01 Optimization of a Tube Formation Assay Using Human Umbilical Vein Endothelial Cells (HUVECs) On a Fibrin Hydrogel for in vitro Evaluation of Angiogenesis.
Supervisor
Master at Faculty of Medicine (Master)
Universidad de Granada, Spain
2015/09/01 - 2022/09/01 Nano-hydroxyapatite/chitosan-based biomaterials for bone regeneration
Supervisor
Engenharia Biomédica (PhD)
Universidade do Porto Faculdade de Engenharia, Portugal
2022/03/04 - 2022/06/30 Biomechanical and rheological evaluation of a fibrin hydrogel blended with collagen to deliver MSCs spheroids for bone tissue engineering application
Supervisor
Licenciatura em Engenharia Metalúrgica e Materiais (Degree)
Universidade do Porto Faculdade de Engenharia, Portugal
2022/03/04 - 2022/06/30 Dental MSC spheroids development for bone tissue engineering
Supervisor
Licenciatura em Engenharia Biomédica (Degree)
Universidade do Porto Faculdade de Engenharia, Portugal
2021/09/15 - 2022/06/30 Development of Dental MSC-Loaded Hydrogel Injected into 3D Bone Graft to Drive Bone Tissue Regeneration
Supervisor
mestrado integrado em medicina dentária (Master)
Universidade do Porto Faculdade de Medicina Dentária, Portugal
2020/09/01 - 2021/07/31 Design of in situ forming hydrogel, with appropriated biochemical, rheological properties to be injected into the 3D scaffold for bone regeneration
Co-supervisor
Ciências de Engenharia, orientação em Engenharia Metalúrgica e de Materiais (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2019/09/01 - 2020/07/31 Therapeutic improvement of Orthopedic bone grafts to prevent infection and promote bone regeneration
Co-supervisor
Ciências de Engenharia, orientação em Engenharia Metalúrgica e de Materiais (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2018/09/01 - 2019/09 Characterization of a collagen/nanohydroxyapatite scaffold for bone regeneration
Supervisor
Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2017/09/01 - 2018/07 In-vitro degradation, mechanical, physical-chemical and morphological characterization of collagen membranes of bovine origin for application in regenerative medicine
Supervisor
Medicina Dentária (Master)
Universidade Católica Portuguesa Centro Regional de Viseu, Portugal
2015/09/01 - 2016/07 Preparation and characterization of collagen-nanohydroxyapatite scaffolds modified with O-phospho-L-serine for bone tissue regeneration
Supervisor
Medicina Dentária (Master)
Universidade Católica Portuguesa Centro Regional de Viseu, Portugal
2014/09/01 - 2015/07 Development of a surface that facilitates cell adhesion to biomedical devices with use in Maxillofacial Surgery, Plastics and Dental Medicine
Supervisor
Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2012/09/01 - 2013/07 Adsorption of SIBLING protein (osteopontin) and cell behavior on collagen surface
Co-supervisor
Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2010/12/01 - 2011/09 Preparation of Collagen-nanoHA Biocomposite Cryogels for Bone Tissue Engineering Applications
Co-supervisor
Engenharia Biomédica (Master)
Universidade do Porto Faculdade de Engenharia, Portugal

Event participation

Activity description
Type of event
Event name
Institution / Organization
2024/09/15 - 2024/09/18 CESB 2024 aims at bringing together two Biomaterials Societies that have been collaborating for many years to bring forward significant advances to the field of Biomaterials with focus on Regenerative Medicine applications. The workshop will review the latest trends and the progress of frontier research in biomaterials science and engineering, including advances in clinical research and translation.
Symposium
The 8th China-Europe Symposium on Biomaterials in Regenerative Medicine (CESB2024)
2022/09/04 - 2022/09/08 The motto of the ESB 2022 Conference is "Innovative Biomaterials and Translational Research". One of the key missions of this conference is to promote interactions between basic researchers, applied scientists, clinicians, and industry in order to drive the development of innovative solutions for clinical applications. We keenly understand that the new solutions to repair or produce tissues or organs will come from the combination of fundamental knowledge and promote the translation of our scientific activity into clinical reality.
Conference
ESB2022 - 32nd Annual Conference of the European Society for Biomaterials
Université de Bordeaux, France
2021/09/05 - 2021/09/09 Poster presentation
Congress
31st Annual Conference of the European Society for Biomaterials (ESB 2021)
Instituto Nacional de Engenharia Biomédica, Portugal

Jury of academic degree

Topic
Role
Candidate name (Type of degree)
Institution / Organization
2020/11/12 Development of functional spheres for bone regeneration
(Thesis) Main arguer
Carlos Alexandre Barros Santos (Master)
Universidade do Porto, Portugal
2020/10/14 Influence of tissue source on the osteogenic potential of mesenchymal stem cells on different materials surfaces
(Thesis) Main arguer
Arkaitz Ruiz (PhD)
Universidad Complutense de Madrid, Spain
2020/09/21 Nanomateriais fluorescentes para aplicações em bioimagem e terapia de cancer in vitro
(Thesis) Main arguer
Isadora Carvalho (PhD)
Universidade Federal de Minas Gerais, Brazil
2020/07/23 Magnetic Scaffolds for Bone Regeneration
(Thesis) Arguer
Matilde Lima de Faria (Master)
Universidade do Porto Faculdade de Engenharia, Portugal
2018/09/17 Neuroimmune Crosstalk in Diseased Human Gingival Tissues
(Thesis) Main arguer
Ana Filipa Silva Sousa (Master)
Universidade do Porto Faculdade de Medicina Dentária, Portugal
2017/07/17 Production and characterization of a nanohydroxyapatite / collagen biocomposite for bone regeneration and drug controlled release
(Thesis) Main arguer
Tatiana Cristina da Silva Padrão (Master)
Universidade do Porto Faculdade de Engenharia, Portugal

AICAR Business School - Neral Campus, India
2014/09 Influence of vancomycin controlled release from heparinized collagen/nanophased hydroxyapatite granules on osteblast and osteoclast cells
(Thesis) Main arguer
Kateline Cristina Mota Piedade (Master)
Universidade de Coimbra, Portugal

Conference scientific committee

Conference name Conference host
2024/05/26 - 2024/05/31 12th World Biomaterials Congress (WBC2024) THE KOREAN SOCIETY FOR BIOMATERIALS
2023/09/04 - 2023/09/08 33rd Annual Conference of the European Society for Biomaterials - ESB2023 European Society for Biomaterials
2021/09/05 - 2021/09/09 31st Annual Conference of the European Society for Biomaterials (ESB 2021) INEB - Instituto de Engenharia Biomédica
2021/08 - 2021/08 4th PhDay Instuto de Investigação e Inovação em Saúde
2020/12 - 2020/12 11th World Biomaterials Congress (WBC2020) International Union of Societies for Biomaterials Science and Engineering

Course / Discipline taught

Academic session Degree Subject (Type) Institution / Organization
2020/09/10 - 2021/01/31 Tissue Repair and Regeneration Biomedical Engineering (Master) Universidade do Porto Faculdade de Engenharia, Portugal
2019/11 - 2019/11 Invited Lecturer - Seminars in Materials Engineering Ciências de Engenharia, orientação em Engenharia Metalúrgica e de Materiais (Mestrado integrado) Universidade do Porto Faculdade de Engenharia, Portugal
2018/02/17 - 2018/07/31 Biomedical Unit V/Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2018/02/16 - 2018/07/31 Basic Unit VIII/Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2017/02/16 - 2017/07/31 Basic Unit VIII/Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2017/02/15 - 2017/07/31 Biomedical Unit V/Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2016/02/15 - 2016/07/31 Biomedical Unit V/Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2016/02/15 - 2016/07/31 basic Unit VIII/Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2015/09/08 - 2016/02/13 Clinical Unit XIV/Dental Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2015/02/16 - 2015/07/31 Basic Unit VIII/Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2015/02/16 - 2015/07/31 Biomedical Unit V/Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2014/09/08 - 2015/02/13 Clinical Unit XXVIII/Regenerative Medicine and Biotechnology Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2014/09/08 - 2015/02/13 Clinical Unit XIV/Dental Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2014/09/08 - 2015/02/13 Clinical Unit VI/Dental Biomaterials Medicina Dentária (Mestrado integrado) Universidade Católica Portuguesa Instituto de Ciências da Saúde Viseu, Portugal
2013/09 - 2014/01 Tissue Repair and Regeneration Bioengenharia (Mestrado integrado) Universidade do Porto Faculdade de Engenharia, Portugal
2012/09/01 - 2013/01/31 Biomedical Engineering Integrated Laboratory III Engenharia Biomédica (Mestrado) Universidade do Porto Faculdade de Engenharia, Portugal

Mentoring / Tutoring

Topic Student name
2023/04/01 - 2023/06/30 Develop next generation of bioengineered scaffolds and understand the mechanobiology interaction to control vascular network assembly and promote angiogenesis Íris Vilariça
2023/02/01 - 2023/06/30 Injectable bioengineering dental MSC spheroids for bone tissue engineering application Inês Maria Barroso Muller

Scientific expedition

Activity description Institution / Organization
2022/01/21 - 2022/02/26 Once upon a time... the bone Through presentations, hands-on activities, experiments, and microscope observation, this module interactively deepens students' knowledge of bones, their functions, composition, problems, and medical strategies for treating bone disease. Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2021/11/17 - 2021/11/24 New Biomaterials: Smart solutions for bone tissue regeneration Oral presentation that focus on the novel biomaterials with structure and chemistry similar to bone. Show projects that are in collaboration with Portuguese companies to transfer technology in the area of orthopedics and dentistry. Demonstrate the use of undifferentiated cells found in tissues that would otherwise be discarded, for example teeth, and understanding their interaction with bone regeneration. Ciência Viva, Portugal
2021/11/02 - 2021/11/13 Stem Cell Awareness day In association with the Portuguese Society of Stem Cells and Cellular Therapies and Ciência Viva, researchers created awareness for this topic among the high school students. For that, it was advertise small talks about stem cells and work related for the public that was available during the week (2-13/11). The schools in Portugal were registered in Ciência Viva to participate in these sessions. Ciência Viva, Portugal
Distinctions

Award

2023 Prémio Alfredo da Silva 2023 - Sustentabilidade em Saúde
Fundação Amélia de Mello, Portugal
2019 UNICAMP Inventors Award
Universidade Estadual de Campinas, Brazil
2005 Honor to Merit
Universidade de São Paulo, Brazil

Other distinction

2012 Individual Postdoctoral fellowship
Fundação para a Ciência e a Tecnologia, Portugal