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PROFILE: A Senior Researcher with extensive experience in Research Project Management within the public and the private sectors. A Highly Collaborative Scientist at the international level with active participation in European Research Networks. A TTO Director with experience and expertise of technology transfer at the academic environment. A Full Professor with teaching skills at the international level. A PhD Degree coupled with a proven track record of publications, patents and contracts with companies. A highly effective negotiator and communicator with great people skills along with strong leadership, problem solving and decision-making abilities and an eye for the bottom-line. ACCOMPLISHMENTS, COLLABORATIONS & LEADERSHIP: I completed my PhD under the supervision of Prof. Víctor S. Martín in the asymmetric synthesis of a variety of biologically active molecules such as lipidic a-amino acids and derivatives, and fused cyclic ethers. I moved to the Vrije Universiteit medisch centrum in Amsterdam (NL), for postdoctoral research with Prof. G. J. Peters getting insight in the molecular pharmacology of anticancer drugs. In 1998, I joined DSM Research in Geleen (NL) to work for three years on the enantioselective membrane separation of pharmaceutically relevant carboxylic acids with Prof. J. G. de Vries. Afterwards, I worked from 2001 to 2003 in Almería (ES) at Deretil in the production of ß-lactam antibiotics. Upon return to the Canary Islands in 2004, I started a screening program aimed at the discovery of new anticancer substances and I successfully established BioLab, an independent research group at ULL. Overall, I coauthored 169 articles in scientific journals collected in the SJR, have participated in numerous congresses with over 200 presentations, co-inventor of 4 granted patents and 1 under evaluation, PI of various competitive funding projects, joined numerous (inter-)national projects, and signed contracts with companies. I have established long-term open collaborations with several academic groups in Europe, Latin-American and Asia. I participate in diverse International Scientific Committees, such as EORTC – Pharmacology and Molecular Mechanisms Group (PAMM) and the Management Committee of COST Actions CM1106, CA15106, CA15135 and CA17104. At BioLab, I have clustered a solid and experienced group of multidisciplinary scientists with expertise in chemistry, biochemistry, pharmacy, engineering and microbiology to develop realistic and collaborative research programs on Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Technology, and Bioprospection of Endemic Plants in the Canary Islands to find therapeutic solutions to human diseases, with a particular focus on -but not limited to- cancer. CONTRIBUTIONS TO SOCIETY: I regularly participate in talks to students from local high schools. I have been interviewed in diverse local and national media to comment on our research and the results. I was appointed Science Communication Manager of COST Action CA17104 and managed all issues related to dissemination of the results of the network including building and keeping updated web pages and social media accounts. I use social media to disseminate the results of our group (@BioLabULL) and from our Institute (@iuboag). Recently, I got the approval of ULL to implement the Transfer Unit BioL4B (BioLab for Business) in order to ease the collaborations with the private sector. TRAINING AND EVALUATION: I have overseen numerous end-of-degree and end-of-master projects, two completed PhD thesis, supervised several postdocs, and over 60 scientific visitors from Europe, Africa and Latin America. I participate as member of the editorial board of diverse scientific journals. I have participated as Advisory Board Member of BioVaria from 2015 to 2017.
Identificação

Identificação pessoal

Nome completo
José Manuel Padrón

Nomes de citação

  • José M. Padrón
  • Padrón, José M.
  • Padrón JM

Identificadores de autor

Ciência ID
FD1A-BFA6-C8FA
ORCID iD
0000-0001-6268-6552
Google Scholar ID
EDAYWm0AAAAJ
Researcher Id
H-5240-2011
Scopus Author Id
7003856521

Telefones

Telefone
  • (+34) 922316502 Ext.: 6126 (Profissional)

Moradas

  • Avenida Astrofísico Francisco Sánchez 2, 38206, La Laguna, La Laguna, Espanha (Profissional)

Websites

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências Exatas - Química - Química Orgânica

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Espanhol; Castelhano (Idioma materno)
Formação
Grau Classificação
1991 - 1996/12/17
Concluído
Chemical Structure and Synthesis of Natural Organic Products (Doctor)
Universidad de La Laguna, Espanha
"ASYMMETRICAL SYNTHESIS OF 2,3,5,6-TETRASUBSTITUTED TETRAHYDROFURANS AND LIPIDIC ALPHA-AMINO ACIDS. FIRST SYNTHESIS OF ALPHA-AMINO-ARAQUIDONIC ACID" (TESE/DISSERTAÇÃO)
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2020/12/14 - Atual Professor Catedrático (Docente Universitário) Universidad de La Laguna, Espanha
2017/01/09 - 2020/12/13 Professor Associado (Docente Universitário) Universidad de La Laguna, Espanha
2011/07/01 - 2017/01/08 Professor Auxiliar (Docente Universitário) Universidad de La Laguna, Espanha
2007/01/01 - 2011/06/30 Leitor (Docente Universitário) Universidad de La Laguna, Espanha

Cargos e Funções

Categoria Profissional
Instituição de acolhimento
Empregador
2023/11/08 - Atual Director de Unidade Orgânica Universidad de La Laguna, Espanha
Universidad de La Laguna Instituto Universitario de Bio-Orgánica Antonio González, Espanha
2019/09 - 2023/11/07 Secretary Universidad de La Laguna, Espanha
Universidad de La Laguna Instituto Universitario de Bio-Orgánica Antonio González, Espanha
2013/04 - 2015/05 Director de Unidade Orgânica Universidad de La Laguna, Espanha
Universidad de La Laguna / Technology Transfer Office, Espanha
Projetos

Bolsa

Designação Financiadores
2022/09 - 2026/09 Targeting cell metabolism in pancreatic ductal adenocarcinoma (STARVING)
PID2021-123059OB-I00
Investigador responsável
Ministerio de Economía y Competitividad
Em curso
2020/01 - 2022/09 New therapeutic strategies for the treatment of pancreatic cancer (TheraPanc)
ProID2020010101
Agencia Canaria de Investigación Innovación y Sociedad de la Información
2018/09 - 2022/09 New diagnostic and therapeutic tools against multidrug resistant tumors (STRATAGEM) European Cooperation in Science and Technology
2019/01 - 2021/12 Sustainable Chemistry: from Small Molecules to Complex Functional Systems (SUSCHEM)
PGC2018-094503-B-C22
Gobierno de España Ministerio de Ciencia e Innovación
2018/01 - 2021/12 Inhibition of glutamine metabolism as therapy for pancreatic ductal adenocarcinoma (METAPANC)
Proyecto Agustín de Betancourt
Cabildo Insular de Tenerife
2020/01 - 2021/06 Early pharmacological profile of marine natural products of the Canary Islands' biodiversity (FARMACAN)
EIS 2020 06_ULL
Agencia Canaria de Investigación Innovación y Sociedad de la Información
2019/06 - 2021/05 Preparation of MSC-ITN action Multitargeted therapies against pancreatic ductal adenocarcinoma (PANCNET)
EIN2019-102928
Gobierno de España Ministerio de Ciencia e Innovación
2016/04 - 2020/10 Multi-target paradigm for innovative ligand identification in the drug discovery process (MuTaLig) European Cooperation in Science and Technology
2016/03 - 2020/03 C-H Activation in Organic Synthesis (CHAOS) European Cooperation in Science and Technology
2016/03 - 2019/12 Development of tocopherol-mimetics using environmentally friendly unconventional synthesis methodologies
FCE_1_2014_1_103499
Agencia Nacional de Investigacion e Innovacion
2016/04 - 2019/04 Steroids as an important source for the synthesis of heterosteroids
CB-2015 256495
Consejo Nacional de Ciencia y Tecnología
2015/04 - 2019/04 Enantioselective synthesis of polyoxygenated metabolites with cytotoxic activity
Grupo No. 1063, Proyecto No. 981
Universidad de la República Comisión Sectorial de Investigación
2015/04 - 2018/04 Synthesis of new steroidal derivatives containing heterocycles spiro, substituted or fused to ring C, D or E, and their evaluation as antioxidants and antiproliferative activity
CB-2014 240329
Consejo Nacional de Ciencia y Tecnología
2015/01 - 2017/12 Phytochemical study of Vernonia acuminata
2014-1D4-01
Fondo Nacional De Innovación y Desarrollo Científico y Tecnológico
2014/01 - 2017/12 Anticancer bioprospecting in endemic and native plants Dominicans in the family Asteraceae
2013-1D4-003
Fondo Nacional De Innovación y Desarrollo Científico y Tecnológico
2013/01 - 2016/12 Search for cytotoxic substances from microscopic fungi
CB-2012-01 181820
Consejo Nacional de Ciencia y Tecnología
2013/01 - 2016/12 Phytochemical study of Elekmania buchii
2012-2013-1D3-4
Fondo Nacional De Innovación y Desarrollo Científico y Tecnológico
2012/12 - 2016/05 Improving Biomedical Research and Innovation in the Canary Islands (IMBRAIN) Research Executive Agency
2012/06 - 2016/04 Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells Research Executive Agency
2013/03 - 2015/02 Development of bioactive molecules using green chemistry methodologies
FCE-2-2011-1-5717
Agencia Nacional de Investigacion e Innovacion
2012/01 - 2014/12 Mechanism of Action of Novel Antitumor Compounds Disruptors of Cell Division
PI11/00840
Instituto de Salud Carlos III
2013/09 - 2014/11 Beyond Imagination: Unveiling the Cellular Universe Fundación Española para la Ciencia y la Tecnología
2012/01 - 2013/06 EORTC-PAMM Group Winter Meeting Ministry of Economy and Competitiveness
2010/12 - 2013/01 Chemoenzymatic synthesis and biological evaluation of oligo-tetrahydrofurans analogous to natural Acetogenins
FCE 2009-3094
Agencia Nacional de Investigacion e Innovacion
2010/04 - 2012/04 Development of new antibacterial and antifungal drugs derived from privileged structures of marine origin
PI43/09
Fundación Canaria de Investigación y Salud
2009/01 - 2012/01 Mechanisms of action of the cytotoxic and/or estrogenic activity of natural phytoestrogens, bioactive lipids and their synthetic analogues
PI2007/021
Agencia Canaria de Investigación Innovación y Sociedad de la Información
2010/01 - 2011/12 Evaluation of molecules of synthetic and natural origin as cytotoxic in search of new leading structures as antitumor drugs
A/025750/09
A/032351/10
Gobierno de Espana Ministerio de Asuntos Exteriores y de Cooperación
2009/01 - 2011/12 Development of new catalytic processes aimed at the synthesis of molecules bioactive
CTQ2008-06806-C02-01/BQU
Gobierno de España
2008/01 - 2011/12 Cooperative Cancer Research Thematic Network (RTICC)
RD06/0020/1046
Instituto de Salud Carlos III
2007/01 - 2011/06 Design, synthesis and antitumor activity of new analogues of privileged structures of marine origin: spisulosin / sphingosine, halogenated cyclic ethers and a,ß-unsaturated ß-hydroxyketones
RYC-2006-001716
Ministerio de Educación y Ciencia
2008/01 - 2011/01 Canary Islands Antitumor Drug Development Network (REDESFAC)
PI01/06
Fundación Canaria de Investigación y Salud
2008/01 - 2011/01 Development of new antitumor drugs derived from privileged structures of marine origin
PI35/06
Fundación Canaria de Investigación y Salud
2005/11 - 2008/11 Efficient construction of privileged structural elements: application to stereoselective synthesis of natural products, biological seeders, and new receptors molecular
CTQ2005-09074-C02-01/BQU
Ministerio de Educación y Ciencia
2006/01 - 2007/12 Obtaining synthetically modified iridoids: theoretical studies and evaluation of their biological activity
A/4014/05
A/6972/06
Gobierno de Espana Ministerio de Asuntos Exteriores y de Cooperación
2006/01 - 2007/12 Stereoselective synthesis of ceramide analogs. Bioactivity evaluation
PROIPRO P20106
Universidad Nacional de San Luis
2006/06 - 2007/06 Implementation of new biological evaluation systems
GC02460601
Gobierno de Canarias
2006 - 2007 Biopolis - Building a European Region
Interreg IIIB 05/MAC/2.3/C14
INTERREG MAC Cooperation Program (Madeira-Azores-Canarias)
2004/05 - 2005/12 Structural and Synthetic Studies of Bioactive Cyclic Ethers of Marine Origin
PPQ2002-04361-C04-02
Gobierno de España
1998/09 - 2001/09 Development of enantioselective receptors for medium to large scale membrane separations of racemic mixtures of carboxylic acid derivatives European Commission
1993/05 - 1996/05 Enantioselective synthesis of biologically active cyclic systems: polyethers, fused g-lactones and 2’,3’-dideoxynucleosides
PB 92-0489
Dirección General de Universidades e Investigación
1993/11 - 1996/01 Endogenous and synthetic inhibitors of phospholipases as medicinal substances European Commission
1991/09 - 1993/12 Total enantioselective synthesis of hemibrevetoxin-b and toxin fragments related
PB 89-0402
Dirección General de Universidades e Investigación
Produções

Publicações

Artigo em conferência
  1. Guillermo Valdomir; Juan Ignacio Padrón; Jenny Saldaña; José Manuel Padrón; Gloria Serra; Eduardo Manta; Victor S. Martín; Danilo Davyt. "Synthesis of hybrids compounds by Click Chemistry and their bioactivities". 2013.
    10.5151/chempro-14bmos-r0081-1
  2. Guillermo Valdomir; José M. Padrón; Juan I. Padrón; Víctor S. Martín; Danilo Davyt. "New modular structures constructed by click chemistry". 2013.
    10.5151/chempro-15bmos-bmos2013_201381919619
  3. Markidis, T.; Padron, J.M.; Constantinou, V.; Martin, T.; Martin, V.S.; Kokotos, G.. "Conversion of chiral unsaturated lipidic amino acids into sphingosine analogs and diamines". 1995.
Artigo em revista
  1. I. Caroline Vaaland; Óscar López; Adrián Puerta; Miguel X. Fernandes; José M. Padrón; José G. Fernández-Bolaños; Magne O. Sydnes; Emil Lindbäck. "Investigation of the enantioselectivity of acetylcholinesterase and butyrylcholinesterase upon inhibition by tacrine-iminosugar heterodimers". Journal of Enzyme Inhibition and Medicinal Chemistry (2023): https://doi.org/10.1080/14756366.2022.2150762.
    10.1080/14756366.2022.2150762
  2. Tereza Hofmanova; Carolina Marques; Alfonso T. García-Sosa; Óscar López; Luisa Leitzbach; Elisabete P. Carreiro; Aday González-Bakker; et al. "N-Substituted 3-Aminooxindoles and N-Propargyl Derivatives: Potential Biological Activities against Alzheimer’s Disease". Results in Chemistry (2023): https://doi.org/10.1016/j.rechem.2023.101032.
    10.1016/j.rechem.2023.101032
  3. Adrián J. Santiago-Benítez; Adrián Puerta; José M. Padrón; Manuel Norte; José J. Fernández; Antonio Hernández Daranas; Francisco Cen-Pacheco. "Antiproliferative effect of natural and semisynthetic polyethers from Laurencia viridis". Natural Product Research (2023): https://doi.org/10.1080/14786419.2023.2280176.
    10.1080/14786419.2023.2280176
  4. Subham G. Patel; Paras J. Patel; Dipti B. Upadhyay; Adrián Puerta; Apoorva Malik; Nagesh K. Kandukuri; Rakesh K Sharma; José M. Padrón; Hitendra M. Patel. "Insights into microwave assisted synthesis of spiro-chromeno[2,3-d]pyrimidines using PEG-OSO3H catalyst: DFT study and their antiproliferative activity". Journal of Molecular Structure (2023): https://doi.org/10.1016/j.molstruc.2023.136174.
    10.1016/j.molstruc.2023.136174
  5. María Sol Ballari; Exequiel O. J. Porta; Evelyn Arel Zalazar; Carla M. Borini Etichetti; José M. Padrón; Javier E. Girardini; Guillermo R. Labadie. "Lipophilic modification of salirasib modulates the antiproliferative and antimigratory activity". Bioorganic & Medicinal Chemistry (2023): https://doi.org/10.1016/j.bmc.2023.117417.
    10.1016/j.bmc.2023.117417
  6. Irene Lagunes; Homero Lumbreras-Martínez; César Espinoza; José M. Padrón; Jorge López-Portillo; Ángel Trigos. "Diversity and bioactivity of sediment-associated fungi from a mangrove forest in Mexico with different conservation conditions". Latin American Journal of Aquatic Research (2023): https://doi.org/10.3856/vol51-issue3-fulltext-2971.
    10.3856/vol51-issue3-fulltext-2971
  7. Jovana B. Araškov; Natalia Maciejewska; Mateusz Olszewski; Aleksandar Višnjevac; Vladimir Blagojevic; Henrique S. Fernandes; Sérgio F. Sousa; et al. "Structural, physicochemical and anticancer study of Zn complexes with pyridyl-based thiazolyl-hydrazones". Journal of Molecular Structure (2023): https://doi.org/10.1016/j.molstruc.2023.135157.
    10.1016/j.molstruc.2023.135157
  8. Mónica Martínez-Montiel; Laura L. Romero-Hernández; Simone Giovannuzzi; Paloma Begines; Adrián Puerta; Ana I. Ahuja-Casarín; Miguel X. Fernandes; et al. "Conformationally Restricted Glycoconjugates Derived from Arylsulfonamides and Coumarins: New Families of Tumour-Associated Carbonic Anhydrase Inhibitors". International Journal of Molecular Sciences (2023): https://www.mdpi.com/1422-0067/24/11/9401.
    10.3390/ijms24119401
  9. Castillo, Q.A.; Padron, J.M.; Keramane, M.; Baez, L.A.; Ovalles, J.N.. "Secondary Metabolites from Chromolaena sinuata var. viscigerum". Chemistry of Natural Compounds (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85151477424&partnerID=MN8TOARS.
    10.1007/s10600-023-03980-2
  10. Roldan-Pena, Jesus M.; Puerta, Adrian; Dinic, Jelena; Stojanov, Sofija Jovanovic; Gonzalez-Bakker, Aday; Hicke, Francisco J.; Mishra, Atreyee; et al. "Biotinylated selenocyanates: Potent and selective cytostatic agents". Bioorganic Chemistry (2023): https://publons.com/wos-op/publon/57032458/.
    10.1016/J.BIOORG.2023.106410
  11. Cobos-Ontiveros, Luis A.; Romero-Hernandez, Laura L.; Mastranzo-Sanchez, Eduardo B.; Colin-Lozano, Blanca; Puerta, Adrian; Padron, Jose M.; Merino-Montiel, Penelope; Baez, Jose Luis Vega; Montiel-Smith, Sara. "Synthesis, antiproliferative evaluation and in silico studies of a novel steroidal spiro morpholinone". Steroids (2023): https://publons.com/wos-op/publon/57032457/.
    10.1016/J.STEROIDS.2023.109173
  12. Carolina S. Marques; Aday González-Bakker; José M. Padrón; Anthony J. Burke. "Easy access to Ugi-derived isatin-peptoids and their potential as small-molecule anticancer agents". New Journal of Chemistry (2023): https://doi.org/10.1039/D2NJ03627D.
    10.1039/D2NJ03627D
  13. Andrés Alguacil; Franco Scalambra; Pablo Lorenzo-Luis; Adrián Puerta; Aday González-Bakker; Zenaida Mendoza; José M. Padrón; Antonio Romerosa. "Tetranuclear Ru2Cu2 and Ru2Ni2 complexes with nanomolar anticancer activity". Dalton Transactions (2023): https://doi.org/10.1039/D3DT01284K.
    10.1039/D3DT01284K
  14. Padilla-Pérez, M.C.; Sánchez-Fernández, E.M.; González-Bakker, A.; Puerta, A.; Padrón, J.M.; Martín-Loro, F.; Arroba, A.I.; García Fernández, J.M.; Mellet, C.O.. "Fluoro-labelled sp2-iminoglycolipids with immunomodulatory properties". European Journal of Medicinal Chemistry 255 (2023): http://www.scopus.com/inward/record.url?eid=2-s2.0-85153893466&partnerID=MN8TOARS.
    10.2139/ssrn.4379429
  15. Suresh Kumar Suthar; Narendra Singh Chundawat; Girdhar Pal Singh; José M. Padrón; Pavan V. Payghan; Yuvraj Kunwar Jhala. "Evaluation of anti-bacterial activity of novel 2, 3-diaminoquinoxaline derivatives: design, synthesis, biological screening, and molecular modeling studies". Egyptian Journal of Basic and Applied Sciences 9 1 (2022): 162-179. https://doi.org/10.1080/2314808X.2022.2049085.
    10.1080/2314808X.2022.2049085
  16. Tereza Cristina Santos Evangelista; Óscar López; Adrián Puerta; Miguel X. Fernandes; Sabrina Baptista Ferreira; José M. Padrón; José G. Fernández-Bolaños; Magne O. Sydnes; Emil Lindbäck. "A hybrid of 1-deoxynojirimycin and benzotriazole induces preferential inhibition of butyrylcholinesterase (BuChE) over acetylcholinesterase (AChE)". Journal of Enzyme Inhibition and Medicinal Chemistry (2022): https://doi.org/10.1080/14756366.2022.2117912.
    10.1080/14756366.2022.2117912
  17. Ruth E. Barrientos; Elena Ibáñez; Adrián Puerta; José M. Padrón; Adrián Paredes; Fredi Cifuentes; Javier Romero-Parra; et al. "Phenolic Fingerprinting and Bioactivity Profiling of Extracts and Isolated Compounds from Gypothamnium pinifolium Phil.". Antioxidants (2022): https://doi.org/10.3390/antiox11122313.
    10.3390/antiox11122313
  18. Vanesa Quintana; Aday González-Bakker; Juan I. Padrón; Víctor S. Martín; José M. Padrón; Danilo Davyt; Guillermo Valdomir. "Synthesis of Oxazole–Tetrahydropyran Hybrids and Study on Their Antiproliferative Activity Against Human Tumour Cells". European Journal of Organic Chemistry (2022): https://doi.org/10.1002/ejoc.202200528.
    10.1002/ejoc.202200528
  19. Martha Velueta-Viveros; Macarena Martínez-Bailén; Adrián Puerta; Laura L. Romero-Hernández; Vladimír Kren; Penélope Merino-Montiel; Sara Montiel-Smith; et al. "Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer’s disease". Bioorganic Chemistry 127 (2022): 105983-105983. https://doi.org/10.1016/j.bioorg.2022.105983.
    10.1016/j.bioorg.2022.105983
  20. Adrián Puerta; Aday González-Bakker; Guido Santos; José M. Padrón. "Early Pharmacological Profiling of Antiproliferative Compounds by Live Cell Imaging". Molecules (2022): https://doi.org/10.3390/molecules27165261.
    10.3390/molecules27165261
  21. Suresh Kumar Suthar; Narendra Singh Chundawat; Girdhar Pal Singh; José M. Padrón; Yuvraj Kunwar Jhala. "Quinoxaline: A comprehension of current pharmacological advancement in medicinal chemistry". European Journal of Medicinal Chemistry Reports (2022): https://doi.org/10.1016/j.ejmcr.2022.100040.
    10.1016/j.ejmcr.2022.100040
  22. Sanja B. Markovic; Natalia Maciejewska; Mateusz Olszewski; Aleksandar Višnjevac; Adrián Puerta; José M. Padrón; Irena Novakovic; et al. "Study of the anticancer potential of Cd complexes of selenazoyl-hydrazones and their sulfur isosters". European Journal of Medicinal Chemistry (2022): https://doi.org/10.1016/j.ejmech.2022.114449.
    10.1016/j.ejmech.2022.114449
  23. Giulia Arrighi; Adrián Puerta; Andrea Petrini; Francisco J. Hicke; Alessio Nocentini; Miguel X. Fernandes; José M. Padrón; et al. "Squaramide-Tethered Sulfonamides and Coumarins: Synthesis, Inhibition of Tumor-Associated CAs IX and XII and Docking Simulations". International Journal of Molecular Sciences (2022): https://doi.org/10.3390/ijms23147685.
    10.3390/ijms23147685
  24. María F. Beer; Guillermo F. Reta; Adrián Puerta; Augusto E. Bivona; Andrés Sánchez Alberti; Natacha Cerny; Emilio L. Malchiodi; et al. "Oxonitrogenated Derivatives of Eremophilans and Eudesmans: Antiproliferative and Anti-Trypanosoma cruzi Activity". Molecules 27 10 (2022): 3067-3067. https://doi.org/10.3390/molecules27103067.
    10.3390/molecules27103067
  25. Carlos Fernández-Galleguillos; Javier Romero-Parra; Adrián Puerta; José M. Padrón; Mario J. Simirgiotis. "Alkaloid Profiling, Anti-Enzymatic and Antiproliferative Activity of the Endemic Chilean Amaryllidaceae Phycella cyrtanthoides". Metabolites 12 2 (2022): 188-188. https://doi.org/10.3390/metabo12020188.
    10.3390/metabo12020188
  26. Paloma Begines; Sergio Martos; Irene Lagunes; Inés Maya; José M. Padrón; Óscar López; José G. Fernández-Bolaños. "Chemoselective Preparation of New Families of Phenolic-Organoselenium Hybrids—A Biological Assessment". Molecules 27 4 (2022): 1315-1315. https://doi.org/10.3390/molecules27041315.
    10.3390/molecules27041315
  27. "Koanolides B-D, new sesquiterpene lactones from Koanophyllon gibbosum". Phytochemistry Letters 47 (2022): 63-66. http://dx.doi.org/10.1016/j.phytol.2021.11.009.
    10.1016/j.phytol.2021.11.009
  28. Óscar López; José M. Padrón. "Iridium- and Palladium-Based Catalysts in the Pharmaceutical Industry". Catalysts 12 2 (2022): 164-164. https://doi.org/10.3390/catal12020164.
    10.3390/catal12020164
  29. "2-Aminobenzoxazole-appended coumarins as potent and selective inhibitors of tumour-associated carbonic anhydrases". Journal of Enzyme Inhibition and Medicinal Chemistry 37 1 (2022): 168-177. http://dx.doi.org/10.1080/14756366.2021.1998026.
    10.1080/14756366.2021.1998026
  30. "Straightforward access to novel mitochondriotropics derived from 2-arylethanol as potent and selective antiproliferative agents". European Journal of Medicinal Chemistry 228 (2022): 113980-113980. http://dx.doi.org/10.1016/j.ejmech.2021.113980.
    10.1016/j.ejmech.2021.113980
  31. Jovana B. Araškov; Aleksandar Višnjevac; Jasminka Popovic; Vladimir Blagojevic; Henrique S. Fernandes; Sérgio F. Sousa; Irena Novakovic; et al. "Zn(ii) complexes with thiazolyl–hydrazones: structure, intermolecular interactions, photophysical properties, computational study and anticancer activity". CrystEngComm (2022): https://doi.org/10.1039/D2CE00443G.
    10.1039/D2CE00443G
  32. Carballo, Ruben M.; Padron, Jose M.; Fernandez, Israel; Cruz, Daniel A.; Grmus, Luana; Martin, Victor S.; Padron, Juan I.. "Iron(III)-Catalyzed Synthesis of 2-Alkyl Homoallyl Sulfonyl Amides: Antiproliferative Study and Reactivity Scope of Aza-Prins Cyclization". The Journal of Organic Chemistry (2022): https://publons.com/wos-op/publon/53479991/.
    10.1021/ACS.JOC.2C01267
  33. Subham G. Patel; Aday González-Bakker; Ruturajsinh M. Vala; Paras J. Patel; Adrián Puerta; Apoorva Malik; Rakesh K. Sharma; José M. Padrón; Hitendra M. Patel. "Microwave-assisted multicomponent synthesis of antiproliferative 2,4-dimethoxy-tetrahydropyrimido[4,5-b]quinolin-6(7H)-ones". RSC Advances (2022): https://doi.org/10.1039/D2RA04669E.
    10.1039/D2RA04669E
  34. Suelsen, Valeria P.; Athanassopoulos, Constantinos M.; Padron, Jose M.; Tamura, Rodrigo E.. "Editorial: Natural compounds as scaffolds for the discovery of new anti-cancer drugs: Focus on terpenoids and flavonoids". Frontiers in Pharmacology (2022): https://publons.com/wos-op/publon/56024718/.
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  35. Ortiz, Federico; Tassano, Tiago; Ingold, Mariana; de la Sovera, Victoria; Puerta, Adrian; Padron, Jose M.; Lopez, Gloria, V; Porcal, Williams. "Greener approach for the synthesis of nitrovinylfurans from biomass-derived 5-hydroxymethyfurfural as selective antiproliferative agents". Sustainable Chemistry and Pharmacy (2022): https://publons.com/wos-op/publon/56024717/.
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  37. Lacret, R.; Puerta, A.; Granica, S.; González-Bakker, A.; Hevia, D.; Teng, Y.; Sánchez-Mateo, C.C.; Pérez de Paz, P.L.; Padrón, J.M.. "Bioactive Potential: A Pharmacognostic Definition through the Screening of Four Hypericum Species from the Canary Islands". Molecules 27 18 (2022): http://www.scopus.com/inward/record.url?eid=2-s2.0-85138405490&partnerID=MN8TOARS.
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  38. Elena M. Sánchez-Fernández; Raquel García-Hernández; Francisco Gamarro; Ana I. Arroba; Manuel Aguilar-Diosdado; José M. Padrón; José M. García Fernández; Carmen Ortiz Mellet. "Synthesis of sp2-Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties". Molecules (2021): https://doi.org/10.3390/molecules26247501.
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  39. "Ugi adducts of isatin as promising antiproliferative agents with druglike properties". Asian Journal of Organic Chemistry (2021): http://dx.doi.org/10.1002/ajoc.202100684.
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  40. Jovana B. Araškov; Milan Nikolic; Stevan Armakovic; Sanja Armakovic; Marko Rodic; Aleksandar Višnjevac; José M. Padrón; Tamara R. Todorovic; Nenad R. Filipovic. "Structural, antioxidant, antiproliferative and in¿silico study of pyridine-based hydrazonyl¿selenazoles and their sulphur isosteres". Journal of Molecular Structure 1240 (2021): 130512-130512. https://doi.org/10.1016/j.molstruc.2021.130512.
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  41. "Novel 1,2,3-triazole epicinchonas: Transitioning from organocatalysis to biological activities". Synthetic Communications (2021): 1-21. http://dx.doi.org/10.1080/00397911.2021.1948575.
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  42. Giovanna Bosica; Kaylie Demanuele; José Manuel Padrón; Adrián Puerta. "Correction: One-pot multicomponent green Hantzsch synthesis of 1,2-dihydropyridine derivatives with antiproliferative activity". Beilstein Journal of Organic Chemistry (2021): https://doi.org/10.3762/bjoc.17.130.
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  43. Carlos Fernández-Galleguillos; Luisa Quesada-Romero; Adrián Puerta; José M. Padrón; Ernane Souza; Javier Romero-Parra; Mario J. Simirgiotis. "UHPLC-MS Chemical Fingerprinting and Antioxidant, Antiproliferative, and Enzyme Inhibition Potential of Gaultheria pumila Berries". Metabolites 11 8 (2021): 523-523. https://doi.org/10.3390/metabo11080523.
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  44. "Bioprospecting Antiproliferative Marine Microbiota From Submarine Volcano Tagoro". Frontiers in Marine Science 8 (2021): http://dx.doi.org/10.3389/fmars.2021.687701.
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  45. Guerra WD; Lucena-Agell D; Hortigüela R; Rossi RA; Díaz JF; Padrón JM; Barolo SM. "Design, Synthesis, and In Vitro Evaluation of Tubulin-targeting Dibenzothiazines with Antiproliferative Activity as Novel Heterocycle Building Block.". ChemMedChem (2021): http://europepmc.org/abstract/med/34231318.
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  46. "In vitro antiproliferative and antioxidant activity of three fungal strains from the White sea". Polar Science (2021): 100724-100724. http://dx.doi.org/10.1016/j.polar.2021.100724.
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  47. Serrano-Márquez L; Trigos Á; Couttolenc A; Padrón JM; Shnyreva AV; Mendoza G. "Antiproliferative and antibacterial activity of extracts of Ganoderma strains grown in vitro.". Food science and biotechnology (2021): http://europepmc.org/abstract/med/34123467.
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  48. Sebastián J. Castro; José M. Padrón; Benjamin Darses; Viviana E. Nicotra; Philippe Dauban. "Late-stage Rh(II)-catalyzed Nitrene Transfer for the Synthesis of Guaianolide Analogs with Enhanced Antiproliferative Activity". European Journal of Organic Chemistry (2021): https://doi.org/10.1002/ejoc.202100074.
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  49. Ruturajsinh M. Vala; Mayank G. Sharma; Divyang M. Patel; Adrián Puerta; José M. Padrón; Venkatachalam Ramkumar; Ramesh L. Gardas; Hitendra M. Patel. "Synthesis and in vitro study of antiproliferative benzyloxy dihydropyrimidinones". Archiv der Pharmazie (2021): https://doi.org/10.1002/ardp.202000466.
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  50. Miguel A. González-Cardenete; Fatima Rivas; Rachel Basset; Marco Stadler; Steffen Hering; José M. Padrón; Ramón J. Zaragozá; María Auxiliadora Dea-Ayuela. "Biological Profiling of Semisynthetic C19-Functionalized Ferruginol and Sugiol Analogues". Antibiotics (2021): https://doi.org/10.3390/antibiotics10020184.
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  51. Padrón, José M.. "Biological Activities of Different Strains of the Genus Ganoderma spp. (Agaricomycetes) from Mexico". International Journal of Medicinal Mushrooms (2021): http://dx.doi.org/10.1615/intjmedmushrooms.2021037451.
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  52. Padrón, José M.. "Tuning the activity of iminosugars: novel N-alkylated deoxynojirimycin derivatives as strong BuChE inhibitors". Journal of Enzyme Inhibition and Medicinal Chemistry 36 1 (2021): 138-146. http://dx.doi.org/10.1080/14756366.2020.1847101.
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  53. Espinoza, C.; Herrera-García, C.D.; Espinosa-García, V.; Couttolenc, A.; Andrade-Torres, A.; Padrón, J.M.; Trigos, Á.. "The antiproliferative potential of fungi associated with coral and algae collected from a Veracruz Reef System, Gulf of Mexico". Latin American Journal of Aquatic Research 49 5 (2021): 843-849. http://www.scopus.com/inward/record.url?eid=2-s2.0-85122909896&partnerID=MN8TOARS.
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  54. Porta, Exequiel O. J.; Ballari, Maria Sol; Padron, Jose M.; Labadie, Guillermo. "Lipophilic Salirasib analogs with enhanced antiproliferative activity against human solid tumor cell lines". ChemRxiv (2021): https://publons.com/wos-op/publon/56024779/.
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  55. Giovanna Bosica; Kaylie Demanuele; José M Padrón; Adrián Puerta. "One-pot multicomponent green Hantzsch synthesis of 1,2-dihydropyridine derivatives with antiproliferative activity". Beilstein Journal of Organic Chemistry (2020): https://doi.org/10.3762/bjoc.16.235.
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  56. Paloma Begines; Lucía Sevilla-Horrillo; Adrián Puerta; Rebecca Puckett; Samuel Bayort; Irene Lagunes; Inés Maya; et al. "Masked Phenolic-Selenium Conjugates: Potent and Selective Antiproliferative Agents Overcoming P-gp Resistance". Pharmaceuticals (2020): https://doi.org/10.3390/ph13110358.
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  57. Padrón, José M.. "Antioxidant, antiproliferative, and acetylcholinesterase inhibition activity of amino alcohol derivatives from 1,4-naphthoquinone". Medicinal Chemistry Research (2020): http://dx.doi.org/10.1007/s00044-020-02617-1.
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  58. Padrón, José M.. "Repurposing old drugs to fight multidrug resistant cancers". Drug Resistance Updates (2020): http://dx.doi.org/10.1016/j.drup.2020.100713.
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  59. Padrón, José M.. "In Vitro and In Silico Screening of 2,4,5-Trisubstituted Imidazole Derivatives as Potential Xanthine Oxidase and Acetylcholinesterase Inhibitors, Antioxidant, and Antiproliferative Agents". Applied Sciences (2020): http://dx.doi.org/10.3390/app10082889.
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  60. Carreiro, E.P.; Sena, A.M.; Puerta, A.; Padrón, J.M.; Burke, A.J.. "Synthesis of Novel 1,2,3-Triazole-Dihydropyrimidinone Hybrids Using Multicomponent 1,3-Dipolar Cycloaddition (Click)-Biginelli Reactions: Anticancer Activity". Synlett 31 6 (2020): 615-621. http://www.scopus.com/inward/record.url?eid=2-s2.0-85082107784&partnerID=MN8TOARS.
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  61. Shams, R.; Aghdaei, H.A.; Behmanesh, A.; Sadeghi, A.; Zali, M.; Salari, S.; Padrón, J.M.. "Micrornas targeting myc expression: Trace of hope for pancreatic cancer therapy. a systematic review". Cancer Management and Research 12 (2020): 2393-2404. http://www.scopus.com/inward/record.url?eid=2-s2.0-85083091830&partnerID=MN8TOARS.
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  63. Patel, D.M.; Patel, H.J.; Padrón, J.M.; Patel, H.M.. "A novel substrate directed multicomponent reaction for the syntheses of tetrahydro-spiro[pyrazolo[4,3-f]quinoline]-8,5'-pyrimidines and tetrahydro-pyrazolo[4,3-f]pyrimido[4,5-b]quinolinesviaselective multiple C-C bond formation under metal-free conditions". RSC Advances 10 33 (2020): 19600-19609. http://www.scopus.com/inward/record.url?eid=2-s2.0-85085640120&partnerID=MN8TOARS.
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  64. Divyang M. Patel; Hetal J. Patel; José M. Padrón; Hitendra M. Patel. "A novel substrate directed multicomponent reaction for the syntheses of tetrahydro-spiro[pyrazolo[4,3-f]quinoline]-8,5'-pyrimidines and tetrahydro-pyrazolo[4,3-f]pyrimido[4,5-b]quinolines via selective multiple C–C bond formation under metal-free conditions". RSC Advances (2020): https://doi.org/10.1039/D0RA02990D.
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  65. Jesús M. Roldán-Peña; Valle Romero-Real; Javier Hicke; Inés Maya; Antonio Franconetti; Irene Lagunes; José M. Padrón; et al. "Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors". European Journal of Medicinal Chemistry 181 (2019): 111550-111550. https://doi.org/10.1016/j.ejmech.2019.07.053.
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  66. Elena M. Sánchez-Fernández; Ma Isabel García-Moreno; Ana I. Arroba; Manuel Aguilar-Diosdado; José M. Padrón; Raquel García-Hernández; Francisco Gamarro; et al. "Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies". European Journal of Medicinal Chemistry 182 (2019): 111604-111604. https://doi.org/10.1016/j.ejmech.2019.111604.
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  67. Alejandra Cortés-Percino; José Luis Vega-Báez; Anabel Romero-López; Adrián Puerta; Penélope Merino-Montiel; Socorro Meza-Reyes; José M. Padrón; Sara Montiel-Smith. "Synthesis and Evaluation of Pyrimidine Steroids as Antiproliferative Agents". Molecules (2019): https://doi.org/10.3390/molecules24203676.
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  68. Irene Lagunes; Paloma Begines; Adrián Silva; Alexis R. Galán; Adrián Puerta; Miguel X. Fernandes; Inés Maya; et al. "Selenocoumarins as new multitarget antiproliferative agents: Synthesis, biological evaluation and in silico calculations". European Journal of Medicinal Chemistry 179 (2019): 493-501. https://doi.org/10.1016/j.ejmech.2019.06.073.
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  69. Padrón, José. "Antiproliferative potential of 3ß,5a,6ß,7a-tetrahydroxyergosta-8(14),22-diene produced by Acremonium persicinum isolated from an alkaline crater lake in Puebla, Mexico". Natural Product Research (2019): http://dx.doi.org/10.1080/14786419.2019.1669032.
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  70. Elena M. Sánchez-Fernández; M. Isabel García-Moreno; Raquel García-Hernández; José M. Padrón; José M. García Fernández; Francisco Gamarro; Carmen Ortiz Mellet. "Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids". Molecules 24 16 (2019): 2882-2882. https://doi.org/10.3390/molecules24162882.
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  71. Sebastián J. Castro; Carina N. Casero; José M. Padrón; Viviana E. Nicotra. "Selective Antiproliferative Withanolides from Species in the Genera Eriolarynx and Deprea". Journal of Natural Products (2019): https://doi.org/10.1021/acs.jnatprod.9b00117.
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  72. Damir Hamulic; Marco Stadler; Steffen Hering; José M. Padrón; Rachel Bassett; Fatima Rivas; Marco A. Loza-Mejía; M. Auxiliadora Dea-Ayuela; Miguel A. González-Cardenete. "Synthesis and Biological Studies of (+)-Liquiditerpenoic Acid A (Abietopinoic Acid) and Representative Analogues: SAR Studies". Journal of Natural Products (2019): https://doi.org/10.1021/acs.jnatprod.8b00884.
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  73. Dinic, J.; Ríos-Luci, C.; Karpaviciene, I.; Cikotiene, I.; Fernandes, M.X.; Pešic, M.; Padrón, J.M.. "CKT0353, a novel microtubule targeting agent, overcomes paclitaxel induced resistance in cancer cells". Investigational New Drugs (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85067282745&partnerID=MN8TOARS.
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  77. Castillo, Q.A.; Padrón, J.M.; Wojtas, L.; Keramane, M.; Germosén, E.A.. "Koanolide A, antiproliferative germacrane-type sesquiterpene lactone from Koanophyllon gibbosum". Tetrahedron Letters 60 25 (2019): 1640-1642. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065926503&partnerID=MN8TOARS.
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  79. Sánchez-Tafolla, L.; Padrón, J.M.; Mendoza, G.; Luna-Rodríguez, M.; Fernández, J.J.; Norte, M.; Trigos, Á.. "Antiproliferative activity of biomass extract from Pseudomonas cedrina". Electronic Journal of Biotechnology 40 (2019): 40-44. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065042942&partnerID=MN8TOARS.
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  80. Brahmbhatt, G.C.; Sutariya, T.R.; Atara, H.D.; Parmar, N.J.; Gupta, V.K.; Lagunes, I.; Padrón, J.M.; Murumkar, P.R.; Yadav, M.R.. "New pyrazolyl-dibenzo[b,e][1,4]diazepinones: room temperature one-pot synthesis and biological evaluation". Molecular Diversity (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85066902075&partnerID=MN8TOARS.
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  82. Filipovic, N.R.; Ristic, P.; Janjic, G.; Klisuric, O.; Puerta, A.; Padrón, J.M.; Donnard, M.; Gulea, M.; Todorovic, T.R.. "Silver-based monomer and coordination polymer with organic thiocyanate ligand: Structural, computational and antiproliferative activity study". Polyhedron 173 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85072584514&partnerID=MN8TOARS.
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  83. Padrón, José M.. "Naphthol-derived Betti bases as potential SLC6A14 blockers". Journal of Molecular and Clinical Medicine (2019): http://dx.doi.org/10.31083/j.jmcm.2019.02.7181.
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  84. Padrón, José M.. "Inhibition of glutamine metabolism as a therapeutic approach against pancreatic ductal adenocarcinoma". (2019):
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  85. Padrón, José M.. "Facts and myths of selective casein kinase 1e inhibition". Journal of Molecular and Clinical Medicine (2018): http://dx.doi.org/10.31083/j.jmcm.2018.04.401.
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  86. Padrón, José M.. "Bioprospecting of fungi with antiproliferative activity from the mangrove sediment of the Tampamachoco coastal lagoon, Veracruz, Mexico". Scientia Fungorum (2018): http://dx.doi.org/10.33885/sf.2018.48.1234.
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  87. Padrón, José M.. "A Small Molecule Tubulin Depolymerizing Agent Identi¿ed by a Phenotypic Drug Discovery Approach". Journal of Molecular and Clinical Medicine (2018): http://dx.doi.org/10.31083/j.jmcm.2018.02.003.
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  88. Padrón, José M.. "Differential mechanism of action of the CK1e inhibitor GSD0054". Journal of Molecular and Clinical Medicine (2018): http://dx.doi.org/10.31083/j.jmcm.2018.02.004.
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  89. Laura L. Romero-Hernández; Penélope Merino-Montiel; Socorro Meza-Reyes; José Luis Vega-Baez; Óscar López; José M. Padrón; Sara Montiel-Smith. "Synthesis of unprecedented steroidal spiro heterocycles as potential antiproliferative drugs". European Journal of Medicinal Chemistry 143 (2018): 21-32. https://doi.org/10.1016/j.ejmech.2017.10.063.
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  90. Begines, P.; Oliete, A.; López, Ó.; Maya, I.; Plata, G.B.; Padrón, J.M.; Fernández-Bolaños, J.G.. "Chalcogen-containing phenolics as antiproliferative agents". Future Medicinal Chemistry 10 3 (2018): 319-334. http://www.scopus.com/inward/record.url?eid=2-s2.0-85041956361&partnerID=MN8TOARS.
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  91. Shnyreva, A.V.; Shnyreva, A.A.; Espinoza, C.; Padrón, J.M.; Trigos, Á.. "Antiproliferative activity and cytotoxicity of some medicinal wood-destroying mushrooms from Russia". International Journal of Medicinal Mushrooms 20 1 (2018): 1-11. http://www.scopus.com/inward/record.url?eid=2-s2.0-85044057437&partnerID=MN8TOARS.
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  95. Castro, S.J.; García, M.E.; Padrón, J.M.; Navarro-Vázquez, A.; Gil, R.R.; Nicotra, V.E.. "Phytochemical Study of Senecio volckmannii Assisted by CASE-3D with Residual Dipolar Couplings and Isotropic 1H/13C NMR Chemical Shifts". Journal of Natural Products 81 11 (2018): 2329-2337. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055654825&partnerID=MN8TOARS.
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  149. Cordova-Guerrero, I.; San Andres, Lucia; Leal-Orozco, Alma E.; Padron, Jose M.; Cornejo-Bravo, J. M.; Leon, Francisco. "New strategy toward the diverted synthesis of oxidized abietane diterpenes via oxidation of 6,7-dehydroferruginol methyl ether with dimethyldioxirane". Tetrahedron Letters 54 33 (2013): 4479-4482.
    10.1016/j.tetlet.2013.06.048
  150. Martin Santos, Cecilia; Cabrera, Silvia; Rios-Luci, Carla; Padron, Jose M.; Lopez Solera, Isabel; Quiroga, Adoracion G.; Medrano, Maria A.; Navarro-Ranninger, Carmen; Aleman, Jose. "Novel clioquinol and its analogous platinum complexes: importance, role of the halogen substitution and the hydroxyl group of the ligand". Dalton Transactions 42 37 (2013): 13343-13348.
    10.1039/c3dt51720a
  151. Sousa, Ines J.; Padron, Jose M.; Fernandes, Miguel X.. "Generation of artificial neural networks models in anticancer study". Neural Computing & Applications 23 3-4 (2013): 577-582.
    10.1007/s00521-013-1404-0
  152. Silveira-Dorta, Gaston; Sousa, Ines J.; Rios-Luci, Carla; Martin, Victor S.; Fernandes, Miguel X.; Padron, Jose M.. "Molecular docking studies of the interaction between propargylic enol ethers and human DNA topoisomerase II alpha". Bioorganic & Medicinal Chemistry Letters 23 19 (2013): 5382-5384.
    10.1016/j.bmcl.2013.07.055
  153. Serrano-Ruiz, Manuel; Manuel Aguilera-Saez, Luis; Lorenzo-Luis, Pablo; Padron, Jose M.; Romerosa, Antonio. "Synthesis and antiproliferative activity of the heterobimetallic complexes [RuClCp(PPh3)-mu-dmoPTA-1 kappa P:2 kappa N-2,N '-MCl2] (M = Co, Ni, Zn; dmoPTA=3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)". Dalton Transactions 42 31 (2013): 11212-11219.
    10.1039/c3dt50829c
  154. Karpaviciene, Ieva; Cikotiene, Inga; Padron, Jose M. "Synthesis and antiproliferative activity of alpha-branched alpha,beta-unsaturated ketones.". European journal of medicinal chemistry 70 (2013): 568-78.
    10.1016/j.ejmech.2013.10.041
  155. Reta GF; Tonn CE; Ríos-Luci C; León LG; Pérez-Roth E; Padrón JM; Donadel OJ; et al. "Cytotoxic bioactivity of some phenylpropanoic acid derivatives.". Natural Product Communications 7 10 (2012): 1341-1346. http://europepmc.org/abstract/med/23157005.
    10.1177/1934578X1200701023
  156. Rios-Luci, Carla; Bonifazi, Evelyn L.; Leon, Leticia G.; Montero, Juan C.; Burton, Gerardo; Pandiella, Atanasio; Misico, Rosana I.; Padron, Jose M.. "beta-Lapachone analogs with enhanced antiproliferative activity". European Journal of Medicinal Chemistry 53 (2012): 264-274.
    10.1016/j.ejmech.2012.04.008
  157. Cabrera-Benitez, Nuria E.; Perez-Roth, Eduardo; Casula, Milena; Ramos-Nuez, Angela; Rios-Luci, Carla; Rodriguez-Gallego, Carlos; Sologuren, Ithaisa; et al. "Anti-Inflammatory Activity of a Novel Family of Aryl Ureas Compounds in an Endotoxin-Induced Airway Epithelial Cell Injury Model". Plos One 7 11 (2012):
    10.1371/journal.pone.0048468
  158. Garcia, Manuela E.; Barboza, Gloria E.; Oberti, Juan C.; Rios-Luci, Carla; Padron, Jose M.; Nicotra, Viviana E.; Estevez-Braun, Ana; Ravelo, Angel G.. "Antiproliferative activity of withanolide derivatives from Jaborosa cabrerae and Jaborosa reflexa. Chemotaxonomic considerations". Phytochemistry 76 (2012): 150-157.
    10.1016/j.phytochem.2011.12.018
  159. Bordón, E.; León, L.G.; Ríos-Luci, C.; Lara, P.C.; Padrón, J.M.. "In vitro synergistic interaction between DTA0100 and radiation in human cancercell lines". Anti-Cancer Agents in Medicinal Chemistry 12 8 (2012): 988-993. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866413012&partnerID=MN8TOARS.
    10.2174/187152012802650057
  160. Nieto, Daniel; Gonzalez-Vadillo, Ana M.; Bruna, Sonia; Pastor, Cesar J.; Rios-Luci, Carla; Leon, Leticia G.; Padron, Jose M.; Navarro-Ranninger, Carmen; Cuadrado, Isabel. "Heterometallic platinum(II) compounds with beta-aminoethylferrocenes: synthesis, electrochemical behaviour and anticancer activity". Dalton Transactions 41 2 (2012): 432-441.
    10.1039/c1dt11358e
  161. Padrón, José M.. "Reactivity and biological properties of a series of cytotoxic PtI2(amine)2 complexes, either cis or trans configured". Inorganic Chemistry 51 3 (2012): 1717-1726. http://www.scopus.com/inward/record.url?eid=2-s2.0-84856689931&partnerID=MN8TOARS.
    10.1021/ic202036c
  162. "Abietane diterpenoids from some salvia species: Chemical transformations and antiproliferative activity". Planta Medica (2012): https://publons.com/wos-op/publon/19048554/.
    10.1055/S-0032-1321023
  163. León LG; Giovannetti E; Alecci C; Giancola F; Funel N; Zucali P; Peters GJ; et al. "Antiproliferative effects of novel aliphatic acetogenin analogs against aggressive solid tumor cell lines.". In Vivo 25 2 (2011): 203-207. http://europepmc.org/abstract/med/21471536.
  164. Aleman, Jose; del Solar, Virginia; Alvarez-Valdes, Amparo; Rios-Luci, Carla; Padron, Jose M.; Navarro-Ranninger, Carmen. "Novel N-sulfonamide trans-platinum complexes: synthesis, reactivity and in vitro evaluation". Medchemcomm 2 8 (2011): 789-793.
    10.1039/c1md00070e
  165. Esteve, Judit; Lorente, Adriana; Romea, Pedro; Urpi, Felix; Rios-Luci, Carla; Padron, Jose M.. "Synthesis and Biological Evaluation of 1-Deoxy-5-hydroxysphingosine Derivatives". European Journal of Organic Chemistry 5 (2011): 960-967.
    10.1002/ejoc.201001268
  166. Rios-Luci, Carla; Leon, Leticia G.; Mena-Cruz, Adrian; Perez-Roth, Eduardo; Lorenzo-Luis, Pablo; Romerosa, Antonio; Padron, Jose M.. "Antiproliferative activity of dmoPTA-Ru(II) complexes against human solid tumor cells". Bioorganic & Medicinal Chemistry Letters 21 15 (2011): 4568-4571.
    10.1016/j.bmcl.2011.05.116
  167. Rios-Luci, Carla; Dominguez-Kelly, Raquel; Leon, Leticia G.; Diaz-Rodriguez, Elena; Freire, Raimundo; Pandiella, Atanasio; Cikotiene, Inga; Padron, Jose M.. "A modular approach to trim cellular targets in anticancer drug discovery". Bioorganic & Medicinal Chemistry Letters 21 22 (2011): 6641-6645.
    10.1016/j.bmcl.2011.09.069
  168. Leon, Leticia G.; Giovannetti, Elisa; Alecci, Claudia; Giancola, Fiorella; Funel, Niccola; Zucali, Paolo; Peters, Godefridus J.; Manuel Padron, Jose. "Cytotoxicity of Aliphatic Acetogenin Analogs against two of the most Aggressive Solid Tumors". The FASEB Journal (2011): https://publons.com/wos-op/publon/11842720/.
  169. Rios-Luci, Carla P.; Leon, Leticia G.; Perez-Roth, Eduardo; Padron, Jose M.. "Endoreduplication induced by a novel family of DNA Topoisomerase II inhibitors". The FASEB Journal (2011): https://publons.com/wos-op/publon/28244206/.
  170. José M. Padrón. "Antimicrobial Drug Resistance (2 volumes). Edited by Douglas L. Mayers.". ChemMedChem 5 6 (2010): 960-961. http://dx.doi.org/10.1002/cmdc.201000025.
    10.1002/cmdc.201000025
  171. Rudys, Simonas; Rios-Luci, Carla; Perez-Roth, Eduardo; Cikotiene, Inga; Padron, Jose M.. "Antiproliferative activity of novel benzo b 1,6 naphthyridines in human solid tumor cell lines". Bioorganic & Medicinal Chemistry Letters 20 5 (2010): 1504-1506.
    10.1016/j.bmcl.2010.01.112
  172. Bonifazi, Evelyn L.; Rios-Luci, Carla; Leon, Leticia G.; Burton, Gerardo; Padron, Jose M.; Misico, Rosana I.. "Antiproliferative activity of synthetic naphthoquinones related to lapachol. First synthesis of 5-hydroxylapachol". Bioorganic & Medicinal Chemistry 18 7 (2010): 2621-2630.
    10.1016/j.bmc.2010.02.032
  173. Messori, Luigi; Casini, Angela; Gabbiani, Chiara; Michelucci, Elena; Cubo, Leticia; Rios-Luci, Carla; Padron, Jose M.; Navarro-Ranninger, Carmen; Quiroga, Adoracion G.. "Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel "Rule-Breaker" Iodidoplatinum(II) Complex". Acs Medicinal Chemistry Letters 1 8 (2010): 381-385.
    10.1021/ml100081e
  174. Machin, Ruben P.; Veleiro, Adriana S.; Nicotra, Viviana E.; Oberti, Juan C.; Padron, Jose M.. "Antiproliferative Activity of Withanolides against Human Breast Cancer Cell Lines". Journal of Natural Products 73 5 (2010): 966-968.
    10.1021/np9006734
  175. Tereza Rojo de Almeida, Maria; Rios-Luci, Carla; Padron, Jose M.; Palermo, Jorge A.. "Antiproliferative terpenoids and alkaloids from the roots of Maytenus vitis-idaea and Maytenus spinosa". Phytochemistry 71 14-15 (2010): 1741-1748.
    10.1016/j.phytochem.2010.06.023
  176. Garcia, Celina; Leon, Leticia G.; Pungitore, Carlos R.; Rios-Luci, Carla; Daranas, Antonio H.; Montero, Juan C.; Pandiella, Atanasio; et al. "Enhancement of antiproliferative activity by molecular simplification of catalpol". Bioorganic & Medicinal Chemistry 18 7 (2010): 2515-2523.
    10.1016/j.bmc.2010.02.044
  177. Leon, Leticia G.; Rios-Luci, Carla; Tejedor, David; Perez-Roth, Eduardo; Montero, Juan C.; Pandiella, Atanasio; Garcia-Tellado, Fernando; Padron, Jose M.. "Mitotic Arrest Induced by a Novel Family of DNA Topoisomerase II Inhibitors". Journal of Medicinal Chemistry 53 9 (2010): 3835-3839.
    10.1021/jm100155y
  178. Rios Luci, Carla Patricia; Leon, Leticia G.; Montero, Juan C.; Tejedor, David; Pandiella, Atanasio; Garcia-Tellado, Fernando; Padron, Jose M.. "Mitotic arrest induced by propargylic enol ethers derivatives". The FASEB Journal (2010): https://publons.com/wos-op/publon/28244207/.
  179. José G. Napolitano; Manuel Norte; José M. Padrón; José J. Fernández; Antonio Hernández Daranas; Napolitano, J.G.; Norte, M.; et al. "Belizeanolide, a Cytotoxic Macrolide from the Dinoflagellate Prorocentrum belizeanum". Angew. Chem. 121 4 (2009): 810-813. http://dx.doi.org/10.1002/ange.200804023.
    10.1002/ange.200804023
  180. Pudziuvelyte, Erika; Rios-Luci, Carla; Leon, Leticia G.; Cikotiene, Inga; Padron, Jose M.. "Synthesis and antiproliferative activity of 2,4-disubstituted 6-aryl-7H-pyrrolo 3,2-d pyrimidin-7-one 5-oxides". Bioorganic & Medicinal Chemistry 17 14 (2009): 4955-4960.
    10.1016/j.bmc.2009.05.078
  181. Leon, Leticia G.; Donadel, Osvaldo J.; Tonn, Carlos E.; Padron, Jose M.. "Tessaric acid derivatives induce G(2)/M cell cycle arrest in human solid tumor cell lines". Bioorganic & Medicinal Chemistry 17 17 (2009): 6251-6256.
    10.1016/j.bmc.2009.07.053
  182. Hubeek, I.; Comijn, E.M.; Van der Wilt, C.L.; Merriman, R.L.; Padron, J.M.; Kaspers, G.J.L.; Peters, G.J.. "CI-994 (N-acetyl-dinaline) in combination with conventional anti-cancer agents is effective against acute myeloid leukemia in vitro and in vivo". Oncology Reports 19 6 (2008): 1517-1523. http://www.scopus.com/inward/record.url?eid=2-s2.0-48849094081&partnerID=MN8TOARS.
    10.3892/or.19.6.1517
  183. Leon, Leticia G.; Machin, Ruben P.; Rodriguez, Carmen M.; Ravelo, Jose L.; Martin, Victor S.; Padron, Jose M.. "gamma-lactones alpha,beta- and beta,gamma-fused to carbocycles as novel antiproliferative drugs". Bioorganic & Medicinal Chemistry Letters 18 19 (2008): 5171-5173.
    10.1016/j.bmcl.2008.08.098
  184. Leon, Leticia G.; Carballo, Ruben M.; Vega-Hernandez, Maria C.; Miranda, Pedro O.; Martin, Victor S.; Padron, Juan I.; Padron, Jose M.. "ß'-Hydroxy-a,ß-Unsaturated Ketones: A new pharmacophore for the design of anticancer drugs. Part 2". Chemmedchem 3 11 (2008): 1740-1747.
    10.1002/cmdc.200800212
  185. "In vitro antiproliferative activity of Xanthones and Guttiferones from Securidaca spp". Planta Medica (2008): https://publons.com/wos-op/publon/11927107/.
    10.1055/S-0028-1084149
  186. Sousa, I; Kairys, V; Padron, J. M.; Fernandes, M. X.. "Identification of molecular targets in anti-cancer therapy using protein-ligand docking". Planta Medica (2008): https://publons.com/wos-op/publon/19048555/.
    10.1055/S-0028-1084827
  187. Bijnsdorp IV; Comijn EM; Padron JM; Gmeiner WH; Peters GJ. "Mechanisms of action of FdUMP[10]: metabolite activation and thymidylate synthase inhibition.". Oncology reports (2007): http://europepmc.org/abstract/med/17549381.
    10.3892/or.18.1.287
  188. I. Cordova; L. G. Leon; F. Leon; L. San Andres; J. G. Luis; J. M. Padron. "Synthesis and Antiproliferative Activity of Novel Sugiol ß-Amino Alcohol Analogues.". ChemInform 38 12 (2007): http://dx.doi.org/10.1002/chin.200712191.
    10.1002/chin.200712191
  189. Bijnsdorp, I.V.; Comijn, E.M.; Padron, J.M.; Gmeiner, W.H.; Peters, G.J.; Bijnsdorp, I. V.; Comijn, E. M.; et al. "Mechanisms of action of FdUMP[10]: Metabolite activation and thymidylate synthase inhibition". Oncology Reports 18 1 (2007): 287-291. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548017882&partnerID=MN8TOARS.
    10.3892/or.18.1.287
  190. Pungitore, C.R.; Padrón, J.M.; Leon, L.G.; García, C.; Ciuffo, G.M.; Martin, V.S.; Tonn, C.E.; et al. "Inhibition of DNA topoisomerase I and growth inhibition of human cancer cell lines by an oleanane from Junellia aspera (Verbenaceae)". Cellular and Molecular Biology 53 3 (2007): 13-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-84965098356&partnerID=MN8TOARS.
    10.1170/T791
  191. Leon, Leticia G.; Carballo, Ruben M.; Vega-Hernandez, Maria C.; Martin, Victor S.; Padron, Juan I.; Padron, Jose M.. "Antiproliferative activity of 2-alkyl-4-halopiperidines and 2-alkyl-4-halo-1,2,5,6-tetrahydropyridines in solid tumor cell lines". Bioorganic & Medicinal Chemistry Letters 17 10 (2007): 2681-2684.
    10.1016/j.bmcl.2007.03.010
  192. Leon, Leticia G.; Miranda, Pedro O.; Martin, Victor S.; Padron, Juan I.; Padron, Jose M.. "Antiproliferative activity of 4-chloro-5,6-dihydro-2H-pyrans. Part 2: Enhancement of drug cytotoxicity". Bioorganic & Medicinal Chemistry Letters 17 11 (2007): 3087-3090.
    10.1016/j.bmcl.2007.03.045
  193. Sanhueza, Carlos A.; Mayato, Carlos; Machin, Ruben P.; Padron, Jose M.; Dorta, Rosa L.; Vazquez, Jesus T.. "Cytotoxic effects of C-glycosides in HOS and HeLa cell lines". Bioorganic & Medicinal Chemistry Letters 17 13 (2007): 3676-3681.
    10.1016/j.bmcl.2007.04.060
  194. Pungitore, Carlos R.; Leon, Leticia G.; Garcia, Celina; Martin, Victor S.; Tonn, Carlos E.; Padron, Jose M.. "Novel antiproliferative analogs of the Taq DNA polymerase inhibitor catalpol". Bioorganic & Medicinal Chemistry Letters 17 5 (2007): 1332-1335.
    10.1016/j.bmcl.2006.11.086
  195. Donadel, Osvaldo J.; Martin, Tomas; Martin, Victor S.; Padron, Jose M.. "Samarium(II) promoted stereoselective synthesis of antiproliferative cis-beta-alkoxy-gamma-alkyl-gamma-lactones". Bioorganic & Medicinal Chemistry Letters 17 1 (2007): 18-21.
    10.1016/j.bmcl.2006.10.005
  196. Carrillo, R.; León, L.G.; Martín, T.; Martín, V.S.; Padrón, J.M.. "Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans. Part 2: Effect of side chain homologation". Bioorganic and Medicinal Chemistry Letters 17 3 (2007): 780-783. http://www.scopus.com/inward/record.url?eid=2-s2.0-33846214455&partnerID=MN8TOARS.
    10.1016/j.bmcl.2006.10.066
  197. "Isolation, chemical transformations, and antiproliferative activity against human cancer cell lines of abietane cliterpenes from two Mexican Salvia species". Planta Medica (2007): https://publons.com/wos-op/publon/19048556/.
  198. Jose M. Padron; Pedro O. Miranda; Juan I. Padron; Victor S. Martin. "ß'-Hydroxy-a,ß-Unsaturated Ketones: A New Pharmacophore for the Design of Anticancer Drugs.". ChemInform 37 28 (2006): http://dx.doi.org/10.1002/chin.200628059.
    10.1002/chin.200628059
  199. Miranda, Pedro O.; Padron, Jose M.; Padron, Juan I.; Villar, Jesus; Martin, Victor S.. "Prins-type synthesis and SAR study of cytotoxic alkyl chloro dihydropyrans". Chemmedchem 1 3 (2006): 323-329.
    10.1002/cmdc.200500057
  200. Padron, J. M.. "Sphingolipids in anticancer therapy". Current Medicinal Chemistry 13 7 (2006): 755-770.
    10.2174/092986706776055553
  201. Crisostomo, F. R. P.; Carrillo, R.; Leon, L. G.; Martin, T.; Padron, J. M.; Martin, V. S.. "Molecular simplification in bioactive molecules: Formal synthesis of (+)-muconin". Journal of Organic Chemistry 71 6 (2006): 2339-2345.
    10.1021/jo0524674
  202. Miranda, P. O.; Leon, L. G.; Martin, V. S.; Padron, J. I.; Padron, J. M.; Pedro O. Miranda; Leticia G. Leon; et al. "One-pot synthesis and SAR study of cis-2,6-dialkyl-4-chloro-tetrahydropyrans". Bioorganic & Medicinal Chemistry Letters 16 12 (2006): 3135-3138. http://dx.doi.org/10.1002/chin.200637123.
    10.1016/j.bmcl.2006.03.064
  203. Cordova, I.; Leon, L. G.; Leon, F.; San Andres, L.; Luis, J. G.; Padron, J. M.. "Synthesis and antiproliferative activity of novel sugiol beta-amino alcohol analogs". European Journal of Medicinal Chemistry 41 11 (2006): 1327-1332.
    10.1016/j.ejmech.2006.06.001
  204. Crisostomo, F. R. P.; Padron, J. M.; Martin, T.; Villar, J.; Martin, V. S.. "A short and efficient enantiomeric synthesis of antitumor fused tetrahydrofurans". European Journal of Organic Chemistry 8 (2006): 1910-1916.
    10.1002/ejoc.200500842
  205. Padron, J. M.; Peters, G. J.. "Cytotoxicity of sphingoid marine compound analogs in mono- and multilayered solid tumor cell cultures". Investigational New Drugs 24 3 (2006): 195-202.
    10.1007/s10637-005-3691-5
  206. Padron, J. M.; Donadel, O. J.; Leon, L. G.; Martin, T.; Martin, V. S.. "Enhancement of drug cytotoxicity by silicon containing groups". Letters in Drug Design & Discovery 3 1 (2006): 29-34.
    10.2174/157018006775240944
  207. Guerrero, Iva N. C.; Andres, Lucia S.; Leon, Leticia G.; Machin, Ruben P.; Padron, Jose M.; Luis, Javier G.; Delgadillo, Jose. "Abietane diterpenoids from Salvia pachyphylla and S-Clevelandii with cytotoxic activity against human cancer cell lines". Journal of Natural Products 69 12 (2006): 1803-1805.
    10.1021/np060279i
  208. Padrón, J.M.; Miranda, P.O.; Padrón, J.I.; Martín, V.S.. "ß'-Hydroxy-a,ß-unsaturated ketones: A new pharmacophore for the design of anticancer drugs". Bioorganic and Medicinal Chemistry Letters 16 8 (2006): 2266-2269. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644807115&partnerID=MN8TOARS.
    10.1016/j.bmcl.2006.01.023
  209. Carrillo, R.; León, L.G.; Martín, T.; Martín, V.S.; Padrón, J.M.. "Synthesis and antiproliferative activity of (2R,3R)-disubstituted tetrahydropyrans". Bioorganic and Medicinal Chemistry Letters 16 23 (2006): 6135-6138. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750531635&partnerID=MN8TOARS.
    10.1016/j.bmcl.2006.08.094
  210. Padron, J. M.; Tejedor, D.; Santos-Exposito, A.; Garcia-Tellado, F.; Martin, V. S.; Villar, J.. "Antiproliferative activity in HL60 cells by tetrasubstituted pyrroles: a structure-activity relationship study". Bioorganic & Medicinal Chemistry Letters 15 10 (2005): 2487-2490.
    10.1016/j.bmcl.2005.03.069
  211. Padron, J. M.; Tejedor, D.; Santos-Exposito, A.; Garcia-Tellado, F.; Villar, J.; Martin, V. S.. "Synthesis and anti-breast cancer activity of tetrasubstituted pyrrole derivatives". Letters in Drug Design & Discovery 2 7 (2005): 529-532.
    10.2174/157018005774479122
  212. Donadel, O. J.; Martin, T.; Martin, V. S.; Villar, J.; Padron, J. M.. "The tert-butyl dimethyl silyl group as an enhancer of drug cytotoxicity against human tumor cells". Bioorganic & Medicinal Chemistry Letters 15 15 (2005): 3536-3539.
    10.1016/j.bmcl.2005.05.126
  213. "Modulation of cytotoxicity by the tert-butyl dimethyl silyl group". Annals of Oncology (2005): https://publons.com/wos-op/publon/5550727/.
  214. "Development of new anticancer drugs from secondary metabolites of marine origin". Journal of Biotechnology (2005): https://publons.com/wos-op/publon/5550722/.
  215. "Secondary metabolites of marine origin in the development of novel anticancer agents.". Clinical Cancer Research (2005): https://publons.com/wos-op/publon/5550719/.
  216. "Induction of apoptosis by fused tetrahydrofuranes". Annals of Oncology (2005): https://publons.com/wos-op/publon/19048558/.
  217. Al-Madhoun, A. S.; van der Wilt, C. L.; Loves, W. J. P.; Padron, J. M.; Eriksson, S.; Talianidis, I.; Peters, G. J.. "Detection of an alternatively spliced form of deoxycytidine kinase mRNA in the 2 '-2 '-difluorodeoxycytidine (gemcitabine)-resistant human ovarian cancer cell line AG6000". Biochemical Pharmacology 68 4 (2004): 601-609.
    10.1016/j.bcp.2004.05.007
  218. "Inhibition of the activity of the native ¿-aminobutyric acidA receptor by metabolites of thyroid hormones: correlations with molecular modeling studies". Brain Research (2004): https://publons.com/wos-op/publon/4260544/.
    10.1016/J.BRAINRES.2003.12.043
  219. Lambers, M.; Beijer, F. H.; Padron, J. M.; Toth, I.; de Vries, J. G.. "Highly selective hydroformylation of the cinchona alkaloids". Journal of Organic Chemistry 67 14 (2002): 5022-5024.
    10.1021/jo0255173
  220. Schmieder-van de Vondervoort, L.; Bouttemy, S.; Padron, J. M.; Le Bras, J.; Muzart, J.; Alsters, P. L.. "Chromium catalyzed oxidation of (homo-)allylic and (homo-)propargylic alcohols with sodium periodate to ketones or carboxylic acids". Synlett 2 (2002): 243-246.
    UNSP 1437-2096,E;2002,0,02,0243,0246,ftx,en;G33001ST.pd
  221. Baragaña, B.; Blackburn, A.G.; Breccia, P.; Davis, A.P.; De Mendoza, J.; Padrón-Carrillo, J.M.; Prados, P.; et al. "Enantioselective transport by a steroidal guanidinium receptor". Chemistry - A European Journal 8 13 (2002): 2931-2936. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037007877&partnerID=MN8TOARS.
    10.1002/1521-3765(20020703)8:13<2931::AID-CHEM2931>3.0.CO;2-H
  222. Kokotos, G.; Constantinou-Kokotou, V.; Padrón, J.M.; Peters, G.J.; Padron, J. M.; Peters, G. J.. "Synthesis and in vitro cytotoxicity of novel long chain busulphan analogues". Bioorganic and Medicinal Chemistry Letters 11 6 (2001): 861-863. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035953059&partnerID=MN8TOARS.
    10.1016/S0960-894X(01)00084-1
  223. Markidis, T.; Padron, J.M.; Martin, V.S.; Peters, G.J.; Kokotos, G.. "Synthesis and in vitro cytotoxicity of long chain 2-amino alcohols and 1,2-diamines". Anticancer Research 21 4 A (2001): 2835-2839. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035149524&partnerID=MN8TOARS.
  224. "Chromium catalyzed oxidations of alcohols with sodium periodate.". Abstracts of Papers of the American Chemical Society (2001): https://publons.com/wos-op/publon/19048559/.
  225. Padrón, J.M.; Van Der Wilt, C.L.; Smid, K.; Smitskamp-Wilms, E.; Backus, H.H.J.; Pizao, P.E.; Giaccone, G.; et al. "The multilayered postconfluent cell culture as a model for drug screening". Critical Reviews in Oncology/Hematology 36 2-3 (2000): 141-157. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033795717&partnerID=MN8TOARS.
    10.1016/S1040-8428(00)00083-4
  226. Backus, H.H.J.; Pinedo, H.M.; Wouters, D.; Padrón, J.M.; Molders, N.; Van Der Wilt, C.L.; Van Groeningen, C.J.; et al. "Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates". International Journal of Cancer 87 6 (2000): 771-778. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033845077&partnerID=MN8TOARS.
    10.1002/1097-0215(20000915)87:6<771::AID-IJC2>3.0.CO;2-V
  227. Padrón, J.M.; Martin, V.S.; Hadjipavlou-Litina, D.; Noula, C.; Constantinou-Kokotou, V.; Peters, G.J.; Kokotos, G.; et al. "Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols". Bioorganic and Medicinal Chemistry Letters 9 6 (1999): 821-826. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033594158&partnerID=MN8TOARS.
    10.1016/S0960-894X(99)00084-0
  228. Padrón, J.M.; Van Moorsel, C.J.A.; Bergman, A.M.; Smitskamp-Wilms, E.; Van Der Wilt, C.L.; Peters, G.J.. "Selective cell kill of the combination of gemcitabine and cisplatin in multilayered postconfluent tumor cell cultures". Anti-Cancer Drugs 10 5 (1999): 445-452. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033437203&partnerID=MN8TOARS.
    10.1097/00001813-199906000-00003
  229. Kokotos, G.; Padron, J. M.; Martin, T.; Gibbons, W. A.; Martin, V. S.. "A general approach to the asymmetric synthesis of unsaturated lipidic alpha-amino acids. The first synthesis of alpha-aminoarachidonic acid". Journal of Organic Chemistry 63 11 (1998): 3741-3744.
    10.1021/jo9715128
  230. Padron, J. M.; Kokotos, G.; Martin, T.; Markidis, T.; Gibbons, W. A.; Martin, V. S.; Padrón, J.M.; et al. "Enantiospecific synthesis of alpha-amino acid semialdehydes: a key step for the synthesis of unnatural unsaturated and saturated alpha-amino acids". Tetrahedron-Asymmetry 9 19 (1998): 3381-3394. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032476172&partnerID=MN8TOARS.
    10.1016/s0957-4166(98)00354-1
  231. Padron, JM; Kokotos, G; Markidis, T; Peters, GJ; Martin, VS. "Unsaturated lipidic a-amino acids derivatives, a novel class of antisignalling agents with cytotoxic activity in vitro". Annals of Oncology (1998): https://publons.com/wos-op/publon/19048560/.
  232. Ramírez, M.A.; Padrón, J.M.; Palazón, J.M.; Martín, V.S.. "Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero-Michael Addition. 6. A Computational Study of the Annelation to 2,3-Disubstituted Tetrahydropyrans". Journal of Organic Chemistry 62 14 (1997): 4584-4590. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030852861&partnerID=MN8TOARS.
    10.1021/jo961925t
  233. Betancort, J.M.; Martín, V.S.; Padrón, J.M.; Palazón, J.M.; Ramírez, M.A.; Soler, M.A.. "Stereocontrolled Synthesis of Cyclic Ethers by Intramolecular Hetero-Michael Addition. 5. Synthesis of All Diastereoisomers of 2,3,5,6-Tetrasubstituted Tetrahydropyrans". Journal of Organic Chemistry 62 14 (1997): 4570-4583. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030876792&partnerID=MN8TOARS.
    10.1021/jo9619241
  234. Kokotos, G.; Padron, J. M.; Noula, C.; Gibbons, W. A.; Martin, V. S.. "A general approach to the enantiomeric synthesis of lipidic alpha-amino acids, peptides and vicinal amino alcohols". Tetrahedron-Asymmetry 7 3 (1996): 857-866.
    10.1016/0957-4166(96)00084-5
  235. "AN ENANTIOSELECTIVE APPROACH TO THE SYNTHESIS OF POLYCYCLIC ETHERS". Anales de Quimica-international Edition (1993): https://publons.com/wos-op/publon/4260583/.
Capítulo de livro
  1. Padrón, José M.. "Synthesis of Highly Substituted Cyclic Ethers and ¿-Lactones in Their Enantiomeric Forms by Stereoselective Cyclizations". 1997.
    10.1002/chin.199927276
Pré-impressão
  1. Olszewski M; Maciejewska N; Kallingal A; Chylewska A; Dabrowska AM; Biedulska M; Makowski M; Padrón JM; Baginski M. "Symmetrically substituted carbazole derivatives exert antiproliferative effects through catalytic inhibition of topoisomerase II and apoptosis induction". 2023. http://europepmc.org/abstract/PPR/PPR648902.
    10.21203/rs.3.rs-2807303/v1

Propriedade Intelectual

Patente
  1. Padrón, José M.. 2014. "Cyclopentanone compounds, method for obtaining them and their use in the preparation of a drug used for treating inflammatory diseases associated with cellular fibrotic and apoptotic processes".
  2. Padrón, José M.. 2013. "Use of a chemical compound derived from a 1,2,3,5-tetrasubstituted pyrole in the preparation of a drug for use in treating inflammatory diseases involving processes of cellular apoptosis".
  3. Padrón, José M.. 2012. "Pyrimidine urea-derived compound for treating inflammatory diseases".
  4. Padrón, José M.. 2001. "Method for producing carboxylic acids by alcohol oxidation".

Outros

Outra produção
  1. Antiproliferative Activity of Cucurbitaceae Species Extracts from Southeast of Mexico. 2019. Morales-Vela K; Pérez-Sánchez FC; Padron JM; Márquez-Fernández O. http://europepmc.org/abstract/PPR/PPR88761.
    10.20944/preprints201908.0127.v1
Atividades

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2011/09 Isolamento e Caracterização de Princípios Activos de Plantas Superiores para o Combate À Tuberculose
Arguente
Sandra Cristina Gonçalves Gouveia (Doutoramento)
Universidade da Madeira, Portugal
Distinções

Prémio

2005 1st Young Cancer Investigators Award
Instituto Canario de Investigación del Cáncer, Espanha
2005 Premio "Ilustre Colegio Oficial de Farmacéuticos de Cádiz"
Academia Iberoamericana de Farmacia, Espanha