???global.info.a_carregar???
Daniela Vilasboas-Campos started working in research in 2016 during her master's thesis entitled: “Evaluation of neuroprotective effects of medicinal plant extracts” at the Life and Health Sciences Research Institute (ICVS) at the Neurosciences Research Domain under supervision of prof. Patrícia Maciel. In 2018, she joined the project entitled: “Whole-exome sequencing of discordant and concordant affected sib pairs in spinocerebellar ataxia 3 (SCA3): a tool to identify novel modifier genes and highlight disrupted molecular pathways”. Her participation in this project was focused on the functional evaluation of genes identified in Machado-Joseph disease patients in C. elegans model of MJD. At the beginning of 2019, Daniela joined the project titled: “Study of the therapeutic effect of autophagy modulating compounds in a C. elegans model of Spinocerebellar ataxia type 3/Machado-Joseph disease”, a collaboration with the company Casma Therapeutics, Inc (USA) and BNML - BEHAVIORAL e MOLECULAR LAB LDA (Portugal). In 2019, Daniela won an individual fellowships financed by the FCT (SFRH/BD/147826/2019), with the project entitled: “Chemogenomics screening for novel therapeutic target identification in a C. elegans model of Machado-Joseph disease”, under supervision of prof. Patrícia Maciel and Dr. Andreia Teixeira-Castro.
Ler resumo completo ↓
Identificação

Identificação pessoal

Nome completo
Daniela Campos

Nomes de citação

  • Vilasboas-Campos, Daniela

Identificadores de autor

Ciência ID
FB11-F347-E8C6
ORCID iD
0000-0001-8786-6680

Endereços de correio eletrónico

  • id8808@alunos.uminho.pt (Profissional)

Websites

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
  • Ciências Médicas e da Saúde - Ciências da Saúde
  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências
  • Ciências Médicas e da Saúde - Medicina Básica - Genética Humana
  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2) Utilizador independente (B2)
Espanhol; Castelhano Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Produções

Publicações

Artigo em revista
  1. Duarte-Silva, Sara; Da Silva, Jorge Diogo; Monteiro-Fernandes, Daniela; Costa, Marta Daniela; Neves-Carvalho, Andreia; Raposo, Mafalda; Soares-Cunha, Carina; et al. "Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of Spinocerebellar ataxia type 3". Journal of Clinical Investigation (2024): http://dx.doi.org/10.1172/jci162246.
    10.1172/jci162246
  2. Francisco Figueiredo; Zsuzsa Sárkány; Alexandra Silva; Daniela Vilasboas-Campos; Patrícia Maciel; Andreia Teixeira-Castro; Pedro M. Martins; Sandra Macedo-Ribeiro. "Drug repurposing of dopaminergic drugs to inhibit ataxin-3 aggregation". Biomedicine & Pharmacotherapy (2023): https://doi.org/10.1016/j.biopha.2023.115258.
    10.1016/j.biopha.2023.115258
  3. Andreia Teixeira-Castro; João Carlos Sousa; Cármen Vieira; Joana Pereira-Sousa; Daniela Vilasboas-Campos; Fernanda Marques; Perpétua Pinto-do-Ó; Patrícia Maciel. "Learning the Biochemical Basis of Axonal Guidance: Using Caenorhabditis elegans as a Model". Biomedicines (2023): https://doi.org/10.3390/biomedicines11061731.
    10.3390/biomedicines11061731
  4. Ana Jalles; Cármen Vieira; Joana Pereira-Sousa; Daniela Vilas Boas da Silva Campos; Ana Francisca Mota; Sara Vasconcelos; Bruna Ferreira-Lomba; et al. "Aripiprazole Offsets Mutant ATXN3-Induced Motor Dysfunction by Targeting Dopamine D2 and Serotonin 1A and 2A Receptors in C. elegans". Biomedicines (2022): https://www.mdpi.com/2227-9059/10/2/370.
    10.3390/biomedicines10020370
  5. Raposo, Mafalda; Bettencourt, Conceição; Melo, Ana Rosa Vieira; Ferreira, Ana F.; Alonso, Isabel; Silva, Paulo; Vasconcelos, João; et al. "Novel Machado-Joseph disease-modifying genes and pathways identified by whole-exome sequencing". Neurobiology of Disease 162 (2022): 105578. http://dx.doi.org/10.1016/j.nbd.2021.105578.
    10.1016/j.nbd.2021.105578
  6. Pereira-Sousa, Joana; Ferreira-Lomba, Bruna; Bellver-Sanchis, Aina; Vilasboas-Campos, Daniela; Fernandes, Jorge H.; Costa, Marta D.; Varney, Mark A.; et al. "Identification of the 5-HT1A serotonin receptor as a novel therapeutic target in a C. elegans model of Machado-Joseph disease". Neurobiology of Disease 152 (2021): 105278. http://dx.doi.org/10.1016/j.nbd.2021.105278.
    10.1016/j.nbd.2021.105278
  7. Vilasboas-Campos, Daniela; Costa, Marta Daniela; Teixeira-Castro, Andreia; Rios, Rejaine; Silva, Fabiano Guimarães; Bessa, Carlos; Dias, Alberto C.P.; Maciel, Patrícia. "Neurotherapeutic effect of Hyptis spp. leaf extracts in Caenorhabditis elegans models of tauopathy and polyglutamine disease: Role of the glutathione redox cycle". Free Radical Biology and Medicine 162 (2021): 202-215. http://dx.doi.org/10.1016/j.freeradbiomed.2020.10.018.
    10.1016/j.freeradbiomed.2020.10.018
  8. Vilasboas-Campos, Daniela; Costa, Marta Daniela; Teixeira-Castro, Andreia; Rios, Rejaine; Silva, Fabiano Guimarães; Aierken, Aili; Zhang, Xiaoying; et al. "Data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases". Data in Brief 33 (2020): 106598. http://dx.doi.org/10.1016/j.dib.2020.106598.
    10.1016/j.dib.2020.106598
Poster em conferência
  1. Oliveira, Stéphanie; Joana Pereira-Sousa; Vilas-Boas Campos, Daniela; Bruna Ferreira-Lomba; kirstein, J; Li, J; Morimoto R.I.. "Serotonin as an endogenous regulator of proteostasis: towards mechanism.". Trabalho apresentado em EMBO Workshop: Proteostasis: From translation to degradation., 2023.
  2. Vilasboas-Campos, Daniela; Lopes, Joana; Bruna Ferreira-Lomba; Jorge Diogo Da Silva; Costa, Marta Daniela; Rodrigues A.I.; Sousa, A; et al. "Unveiling Promising Compounds for Boosting Proteostasis: A Rapid Whole-Organism Phenotypic Assay.". Trabalho apresentado em EMBO Workshop: Proteostasis: From translation to degradation., 2023.
  3. Francisco Figueiredo; Sárkány, Zsuzsa; Alexandra Silva; Vilasboas-Campos, Daniela; Maciel, Patrícia; Teixeira-Castro, Andreia; Martins, Pedro M.; Macedo-Ribeiro, Sandra. "Repurposing dopaminergic drugs to prevent Ataxin-3 aggregation". Trabalho apresentado em III phasage internatonal conference, multiscale understanding of protein aggregation and biomolecular condensates in aging and disease., 2023.
  4. Vilasboas-Campos, Daniela; Teixeira-Castro, Andreia; Joana Lopes; Bruna Ferreira-Lomba; Jorge Diogo Da Silva; Costa, Marta Daniela; Rodrigues A.I.; et al. "Identification of novel molecules with proteostasis enhancement activity using a whole-animal based fast-throughput phenotypic assay.". Trabalho apresentado em 6th Symposium on Medicinal Chemistry of the University of Minho. Braga, Portugal., 2023.
  5. Bruna Ferreira-Lomba; Guerreiro, Sara R.; Duarte-Silva, S; Cunha-Garcia, Daniela ; Teixeira-Castro, Andreia; Vilasboas-Campos, Daniela; Vidinha-Mira, André; Maciel, Patrícia. "Motor coordination and balance ameliorated after treatment of the CMVMJD135 mouse model of Spinocerebellar Ataxia Type 3 with befiradol". 2022.
  6. Jorge Humberto Fernandes; Vilasboas-Campos, Daniela; Costa, Marta Daniela; Wang, Q; Alberto C. P. Dias; Maciel, Patrícia. "Neuroprotective effect of a Hemerocallis citrina extract in a C. elegans model of Machado-Joseph disease.". Trabalho apresentado em International Congress for Ataxia Research (ICAR) 2022., 2022.
  7. Sara F. C. Guerreiro; Bruna Ferreira-Lomba; Cunha-Garcia, Daniela ; Duarte-Silva, S; Joana Pereira-Sousa; Vilasboas-Campos, Daniela; Vidinha-Mira, André; Teixeira-Castro, Andreia; Maciel, Patrícia. "Preclinical study of a 5-HT1A receptor specific agonist in the CMVMJD135 mouse model of Machado-Joseph disease.". Trabalho apresentado em International Society for Neurochemistry-Asian Pacific Society of Neurochemistry (ISN-APSN) meeting 2022, Honolulu, USA., 2022.
  8. Bruna Ferreira-Lomba; Sara F. C. Guerreiro; Cunha-Garcia, Daniela ; Duarte-Silva, S; Joana Pereira-Sousa; Vilasboas-Campos, Daniela; Vidinha-Mira, André; Teixeira-Castro, Andreia; Maciel, Patrícia. "Pre- and post-symptomatic treatment with NLX-112 improved the balance and motor coordination of the CMVMJD135 mouse model of Machado-Joseph Disease". 2022.
  9. Laranjeira, I; Vilasboas-Campos, Daniela; Castro, A.; Almeida, A.; Maciel, P.; Pinto-Ribeiro, F.; Dias, A.C.P.. "Pterospartum tridentatum: phytochemical profile and antioxidant activity of methanolic extracts.". 2021.
  10. Maira C. M. Fonseca; Maria Aparecida N. Sediyama; Glyn M. Figueira; Vilasboas-Campos, Daniela; Carlos Bessa; Marta D. Costa; Patrícia Maciel; Alberto C. P. Dias. "Neuroprotective and antioxidant effects of Maranta arundinacea and Porophyll umruderale extracts in Caenorhabditis elegans.". Trabalho apresentado em Internacional Online Phytotherapy Conference. INTERPHYTO. Brasília., 2021.
  11. Pereira-Sousa J; Jalles A; Vilasboas-Campos, Daniela; Ferreira-Lomba B; Da Silva JD; Varney MA; Newman-Tancredi A; Maciel P ; Teixeira-Castro A. "Targeting of the serotonin (1A) receptor suppresses mutant ataxin-3 pathogenesis in C. elegans.". Trabalho apresentado em International Ataxia Research Conference (IARC). Washington DC, USA, 2019.
  12. Mafalda Raposo; Ana Rosa Vieira Melo; Vilasboas-Campos, Daniela; Ana Ferreira; João Vasconcelos; Isabel Alonso; Paulo Silva; et al. "Identification of novel genetic modifiers of machado-joseph disease (MJD/SCA3) using whole-exome sequencing.". Trabalho apresentado em International Machado-Joseph Research Disease Conference., 2019.
  13. Mafalda Raposo; Ana Rosa Vieira Melo; Vilasboas-Campos, Daniela; Ana Ferreira; João Vasconcelos; Isabel Alonso; Paulo Silva; et al. "Identification of novel genetic modifiers of machado-joseph disease (MJD/SCA3) using whole-exome sequencing.". Trabalho apresentado em International Ataxia Research Conference (IARC). Washington DC, USA, 2019.
  14. Maira C. M. Fonseca; Maria Aparecida N. Sediyama; Glyn M. Figueira; Vilasboas-Campos, Daniela; Carlos Bessa; Marta D. Costa; Patrícia Maciel; Alberto C. P. Dias. "Neuroprotective and antioxidant effects of Maranta arundinacea and Porophyllum ruderale in Caenorhabditis elegans.". Trabalho apresentado em Food Chemistry Conference, Spain., 2019.
  15. Vilas-Boas Campos, Daniela. "whole-exome sequencing of discordant and concordant affected sib pairs in spinocerebellar ataxia 3 (SCA3): a tool to identify novel modifier genes and highlight disrupted molecular pathways.". Trabalho apresentado em XII NeRD retreat - ICVS/3Bs, 2018.
  16. Vilas-Boas Campos, Daniela. "Antioxidant and neuroprotective effects of Hyptis suaveolens, Hyptis pectinata and Hyptis marrubioides in Caenorhabditis elegans.". Trabalho apresentado em International Conference on Medicinal Plants and Bioeconomy (ICMPB) & The 1st Sino-CPLP Symposium on Natural Products and Biodiversity Resources (SNPBR)., 2018.
  17. Vilas-Boas Campos, Daniela. "The neuroprotective effect of Hyptis suaveolens, Hyptis pectinata and Hyptis marrubioides in Caenorhabditis elegans model of SCA3/MJD.". Trabalho apresentado em 7th Ataxia Investigators Meeting (AIM), 2018.
  18. Vilas- Boas Campos, Daniela. "Neuroprotective effects of Hyptis plant extracts in C. elegans models of neurodegeneration". Trabalho apresentado em Neuroscience Forum - XI NeRD Retreat, 2017.
Resumo em conferência
  1. Vilas-Boas Campos, Daniela. "Antioxidant and neuroprotective effects of Hyptis suaveolens, Hytis pectinata and Hyptis marrubioides in Caenorhabditis elegans". Trabalho apresentado em The International Conference on Medicinal Plants and Bioeconomy & the 1st Sino-CPLP Symposium on Natural Products and Biodiversity Resources., Macau, 2018.
    Publicado • https://doi.org/10.1186/s13020-018-0213-x

Outros

Conjunto de dados
  1. Vilas-Boas Campos, Daniela. Raw data on the effects of Hyptis spp. and Lycium spp. plant extracts in C. elegans models of genetically determined neurodegenerative diseases. Mendeley data.