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I have been working at the Center for Neuroscience & Cell Biology (CNC) since 1997. In 1998, I obtained my BSc degree in Biology, Speciality of Scientific Research (Pre-Bologna process), at the Faculty of Sciences & Technology (FCTUC),University of Coimbra,under the supervision of Prof C.R. Oliveira and Dr M.S. Santos, with a score of Good (15 values; 0-20 scale). In 2002, I obtained my MSc degree in Cell Biology (Pre-Bologna process; FCTUC), under the supervision of Prof C.R. Oliveira and Dr M.S. Santos, with the highest score available: Suma cum laude. In 2007, I obtained my PhD degree in Biology, Speciality of Cell Biology (FCTUC), under the supervision of Prof A.C. Rego and Dr M.S. Santos, again with the highest score available: Suma cum laude. From 2007-2010, I did my 1st Triennium Post-Doc, under the supervision of Prof A.C. Rego, C.R. Oliveira and Dr M.S. Santos. During this triennium, I also worked abroad for 9 months at the Neuronal Survival Unit, Wallenberg Neuroscience Center, Lund Medical School, Lund University (Sweden), under the supervision of Prof P. Brundin, M. Björkqvist, D. Nicholls and J.-Y. Li. From 2010-2016, I did my 2nd and 3rd Triennia Post-Doc, under the supervision of Prof P.I. Moreira, C.R. Oliveira and Dr M.S. Santos. During this time, I worked abroad for plus 6 months at the Biomarkers in Brain Disease Unit, Lund Medical School, Lund University, Lund (Sweden), under the supervision of Prof M. Björkqvist. From 2016-2019, I did my 4th Triennium Post-Doc at CNC, under the supervision of Prof P.I. Moreira, M. Björkqvist, C.R. Oliveira and Dr M.S. Santos. From January 2019 to August 2020, I was a Post-Doctoral Researcher at CNC, working at the Metabolism, Mitochondria & Hormones in Brain Disorders Lab (included in the Cell Signaling & Metabolism in Disease Group), headed by Prof P.I. Moreira. In September 2020, I moved to the MitoXT - Mitochondrial Toxicology & Experimental Therapeutics Lab (included in the Mitochondria, Metabolism & Disease Group, headed by Dr Paulo J. Oliveira), as a Post-Doctoral Researcher. My current research interests include the mechanisms underlying amyotrophic lateral sclerosis (ALS), cardiomyopathy and skin senescence, alongside the therapeutic potential of novel metabolism-/mitochondria-targeted antioxidants. Previously, I studied the mechanisms underlying metabolic and neurodegenerative diseases (Huntington's and Alzheimer's diseases) and reproductive aging, together with the potential neuroprotection by non-pharmacological and pharmacological approaches (including anti-diabetes drugs). My extensive work and collaboration with different research groups within and outside CNC and UC allowed me to obtain different scientific, technical, personal know-how that has been crucial to understand metabolic and neurodegenerative diseases and reproductive aging in a more integrated perspective, to challenge my views of their gaps, potential crosslinkers and, ultimately, their boundaries. It was this perspective and my curious and challenging spirit that boosted me to recently embrace new areas (Cardiology and Dermatology) to learn new subjects and to eventually apply my knowledge from Neuroscience/Neuroendocrinology/Neuropharmacology to the study of ALS, cardiomyopathy and skin senescence. For me, this is the way (together with my intense Science outreach activities devoted to lay and non-lay public, and my voluntary work with dementia patients) to contribute to Knowledge and Science that impact our Societies. I published 53 articles in journals (Hi=33;3262 citations;total IF=188.2;RCR=94.6; 1 top 3%, 1 top 5%, 4 top 10%). According to Expertscape database, I am a top 1% worldwide expert in dementia, insulin, IGF-1, peptide hormones, mitochondria; top 2% expert in oxidative stress, Alzheimer's and Huntington's diseases. I interacted with 112 collaborators in the (co-)authorship of project proposals (some already funded) and scientific papers. Publons ID: publons.com/a/1181513/
Identificação

Identificação pessoal

Nome completo
Ana Isabel Marques Duarte

Nomes de citação

  • Duarte, Ana
  • Duarte AI
  • Duarte Ana I
  • Duarte A

Identificadores de autor

Ciência ID
FA15-C7D7-2CBE
ORCID iD
0000-0002-0223-7867
Google Scholar ID
https://scholar.google.com/citations?user=pDCJVr0AAAAJ&hl=pt-PT
Researcher Id
C-9936-2009
Scopus Author Id
7102601977

Endereços de correio eletrónico

  • ana.duarte@cnc.uc.pt (Profissional)

Telefones

Telefone
  • 231249195 Ext.: 731 (Profissional)

Moradas

  • CNC - Center for Neuroscience and Cell Biology, University of Coimbra; MitoXT-Mitochondrial Toxicology & Experimental Therapeutics Laboratory; UC Biotech Building, Lot 8A, Biocant Park, 3060-197, Cantanhede, Cantanhede, Portugal (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Ciências da Saúde
  • Ciências Naturais - Ciências Biológicas - Biologia Celular

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Francês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Sueco Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2007
Concluído
PhD in Biology - Speciality: Cell Biology (Doutoramento)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Influence of oxidative stress and type 2 diabetes mellitus on neuronal function and metabolism - the protective role of insulin" (TESE/DISSERTAÇÃO)
Distinction suma cum laude
2007
Concluído
Biologia (Doutoramento)
Especialização em Especialidade: Biologia Celular
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Influence of Oxidative Stress and Type 2 Diabetes Mellitus on Neuronal Function and Metabolis - the Neuroprotective Role of Insulin - Efeito do Stress Oxidativo e Metabolismo Neuronal - Papel Neuroprotector da Insulina" (TESE/DISSERTAÇÃO)
2002
Concluído
Master in Cell Biology (Pre-Bologna) (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Membrane ATPases, neurotransmitter uptake and oxidative stress: influence of diabetes and aging. A study in rat brain cortical synaptosomes" (TESE/DISSERTAÇÃO)
Distinction suma cum laude
1998
Concluído
Biology - Speciality: Scientific Research (Pre-Bologna) (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Effect of oxidative stress in rat brain cortical synaptosomes" (TESE/DISSERTAÇÃO)
Good (final score: 15 values; scale: 0-20 values)
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2019/01/04 - Atual Investigador Contratado (Investigação) Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
2016/12/01 - 2019/01/03 Pós-doutorado (Investigação) CNC.IBILI, Portugal
2013/12/01 - 2016/11/30 Pós-doutorado (Investigação) CNC.IBILI, Portugal
2015/10/01 - 2016/03/31 Investigador visitante (Investigação) Lunds Universitet Wallenberg Neuroscience Center, Suécia
2010/12/01 - 2013/11/30 Pós-doutorado (Investigação) CNC.IBILI, Portugal
2007/12/01 - 2010/11/30 Pós-doutorado (Investigação) CNC.IBILI, Portugal
2008/09/01 - 2009/05/31 Investigador visitante (Investigação) Lunds Universitet Wallenberg Neuroscience Center, Suécia

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2002/05/01 - 2006/04/30 PhD Fellow CNC.IBILI, Portugal
2004/10/17 - 2004/10/24 Visiting PhD Student Universitat de València Facultat de Medicina i Odontologia, Espanha
2000/05/01 - 2002/04/30 MSc Fellow CNC.IBILI, Portugal
1998/10/01 - 2000/04/30 Research Technician Fellow (BSc) CNC.IBILI, Portugal
Projetos

Projeto

Designação Financiadores
2021 - 2023/05/31 Função da homeostasia tiol-mitocondrial na neurodegeneração: implicações para a esclerose lateral amiotrófica
EXPL/BTM-TEC/1407/2021
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021 - 2023/05/31 BraveHEART: Melhorar a Natureza Através do Direcionamento de Moléculas Bioactivas Polifenólicas da Dieta para as Mitocôndrias para Minimizar as Complicações Cardíacas Associadas à Doença de Fígado Gordo Não Alcoólico
EXPL/BIA-BQM/1361/2021
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia, I.P.
Em curso
2021 - 2022/02/28 Development of new mitochondria-targeted antioxidants to ameliorate the phenotype of the familial SOD1 amyotrophic lateral sclerosis (MITO4ALS)
POCI-01-0145-FEDER-029391, PTDC/MED-FAR/29391/2017
Investigador responsável
Fundação para a Ciência e a Tecnologia
Em curso
2020 - 2021/07/31 Skinshield
POCI-01-0145-FEDER-028607
Collaborator
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2018 - 2021/07/31 MITOSCREENING
MITOSCREENING
Collaborator
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2020 - 2021/02/28 Development of new mitochondria-targeted antioxidants to ameliorate the phenotype of the familial SOD1 amyotrophic lateral sclerosis (MITO4ALS)
POCI-01-0145-FEDER-029391, PTDC/MED-FAR/29391/2017
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia, I.P.
Em curso
2018 - 2019/08/31 Brain protection by Evolocumab in individuals at high risk for cardiovascular disease: from bench to bedside
PEPITA
Investigador
Universidade de Coimbra Faculdade de Medicina, Portugal
Banco Santander Totta
Concluído
2018 - 2019/07/31 Modulation of transcriptional activity by histone deacetylase inhibitors in Alzheimer’s disease
POCI-01-0145-FEDER-032316
Collaborator
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2016 - 2018/12 Targeting huntingtin proteostasis and mitochondria to prevent neuronal dysfunction in Huntington’s disease
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2015 - 2016/05/31 Ghrelin, potential treatment of Huntington’s disease pathology
Seed Project #748
Co-Applicant
European Huntington’s Disease Network (EHDN)
Concluído
2013 - 2015/11/30 Tackling Alzheimer's Disease with a new peptide inhibitor of BACE1
Investigador
Fundação para a Ciência e a Tecnologia
Concluído
2012 - 2014/10/31 The impact of exendin-4 therapy in the molecular mechanisms underlying type 2 diabetes-related long-term brain dysfunction
Investigador responsável
Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2011 - 2014/08 Protective Activity of SIRT3 Against Drug-induced Mitochondrial Dysfunction
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2011 - 2013/08 Mitochondrial preconditioning: potential neuroprotective effect in Alzheimer's disease
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2010 - 2013/03 The pathological interaction between diabetes and Alzheimer's disease: exploring the role of brain endothelial mitochondria and uncoupling proteins
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2011 - 2012/01 Influence of gender on the molecular mechanisms underlying aging-related changes in diabetic brain: The impact of insulin therapy
Faculty of Medicine (PMADSC-2011)
Co-PI
Universidade de Coimbra
Concluído
2007 - 2010/11 Neuroprotective role of insulin and IGF-1 against Huntington´s disease-associated diabetes
Investigador
Fundação para a Ciência e a Tecnologia, I.P.
Concluído
2008 - 2010/01 Influence of insulin and IGF-1 on oxidative stress and cell viability in a model of diabetes associated with Huntington's disease
Faculty of Medicine, Gabinete de Apoio a Projectos de Investigação
Co-PI
Universidade de Coimbra
Concluído
2008 - 2009/05/31 Studera neuroprotektiv effekt av insulin och IGF-1 på en transgen musmodell med Huntingtons sjukdom ("Study of the neuroprotective effect of insulin and IGF-1 in a transgenic mouse model of Huntington’s disease")
MS201-08
Bolseiro de Cientista Convidado
Lunds Universitet Wallenberg Neuroscience Center, Suécia
Concluído
2008 - 2009/05/31 Effect of Huntington’s disease on skeletal muscle and blood platelets bioenergetics in a transgenic mouse model
N/A
Bolseiro de Cientista Convidado
Lunds Universitet Wallenberg Neuroscience Center, Suécia
Concluído
2000 - 2003 Mitochondria and diabetes: mitochondrial function in the heart and brain of a rat model of non-insulin-dependent diabetes mellitus (Goto-Kakizaki)
N/A
Bolseiro de Doutoramento
CNC.IBILI, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
1999 - 2002 A comparative study of the neurotoxic mechanisms of prion and amyloid-beta peptides. Potential neuroprotective strategies
N/A
Bolseiro de Mestrado
CNC.IBILI, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Lopes, C.; Duarte, A.I.; Hayden, M.; Rego, A.C.. "Peripheral and cerebral metabolic features in an animal model of Huntington's disease". 2012.
    10.1109/ENBENG.2012.6331390
  2. Duarte AI. "Insulin neuroprotection against oxidative stress involves increased antioxidant defenses and glucose metabolism". Trabalho apresentado em European Meeting of the Society for Free Radical Research International 2007, 2007.
Artigo em jornal
  1. Duarte AI. "Viagens sem insónias, a Comics written together with other researchers from CNC.IBILI about the "World Sleep Day 2018"", Público, 2018, https://www.publico.pt/2018/03/16/ciencia/fotogaleria/viagens-sem-insonias-381315.
  2. Duarte AI. "Viagens na Diabetes, a Comics written together with other researchers from CNC.IBILI about the "World Diabetes Day 2017"", Público, 2017, https://www.publico.pt/2017/11/14/fotogaleria/viagens-na-diabetes-em-bd-378982.
  3. Duarte AI. "Mecanismo explica como o sexo e a diabetes influenciam o aparecimento da Doença de Alzheimer", Published in >40 Portuguese newspapers and resulted in one interview for the TV show “Mentes que brilham”, from Porto Canal., 2017
Artigo em revista
  1. Susana P. Pereira; Ludgero C. Tavares; Ana I. Duarte; Inês Baldeiras; Teresa Cunha-Oliveira; João D. Martins; Maria S. Santos; et al. "Sex-dependent vulnerability of fetal nonhuman primate cardiac mitochondria to moderate maternal nutrient reduction". Clinical Science 135 9 (2021): 1103-1126. https://doi.org/10.1042/CS20201339.
    10.1042/CS20201339
  2. Ana I. Duarte; Emanuel Candeias; Inês N. Alves; Débora Mena; Daniela F. Silva; Nuno J. Machado; Elisa J. Campos; et al. "Liraglutide Protects Against Brain Amyloid-ß1–42 Accumulation in Female Mice with Early Alzheimer’s Disease-Like Pathology by Partially Rescuing Oxidative/Nitrosative Stress and Inflammation". International Journal of Molecular Sciences (2020): https://doi.org/10.3390/ijms21051746.
    10.3390/ijms21051746
  3. Lietzau, Grazyna; Magni, Giulia; Kehr, Jan; Yoshitake, Takashi; Candeias, Emanuel; Duarte, Ana; Pettersson, Hans; et al. "Dipeptidyl peptidase-4 inhibitors and sulfonylureas prevent the progressive impairment of the nigrostriatal dopaminergic system induced by diabetes during aging". Neurobiology of Aging (2020): http://dx.doi.org/10.1016/j.neurobiolaging.2020.01.004.
    10.1016/j.neurobiolaging.2020.01.004
  4. Pinho, Brígida R.; Duarte, Ana I.; Canas, Paula M.; Moreira, Paula I.; Murphy, Michael P.; Oliveira, Jorge M.A.. "The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington's disease mice". Free Radical Biology and Medicine 146 (2020): 372-382. http://dx.doi.org/10.1016/j.freeradbiomed.2019.11.021.
    10.1016/j.freeradbiomed.2019.11.021
  5. Duarte AI; Pereira SP, Tavares LC, Duarte AI, Baldeiras I, Cunha-Oliveira T, Santos MS, Maloyan A, Moreno AJ, Cox LA, Li C, Nath. "Moderate global maternal nutrient reduction remodels fetal cardiac left ventricular mitochondria in a non-human primate species at 0.9 gestation". (2020):
    Submetido
  6. Duarte AI; Duarte AI*,§, Candeias E*, Alves IN, Mena D, Silva DF, Machado NJ, Campos EJ, Santos MS, Oliveira CR, Moreira PI§. "Liraglutide protects against brain amyloid-ß1-42 accumulation in female mice with early Alzheimer’s disease-like pathology by partially rescuing oxidative/nitrosative stress and inflammation". International Journal of Molecular Sciences (2020):
    Acesso aberto • Aceite para publicação
  7. Duarte, Ana. "Current and emerging avenues for Alzheimer's disease drug targets". Journal of Internal Medicine (2019): http://dx.doi.org/10.1111/joim.12959.
    10.1111/joim.12959
  8. Ana I. Duarte; Marie Sjögren; Maria S. Santos; Catarina R. Oliveira; Paula I. Moreira; Maria Björkqvist. "Dual Therapy with Liraglutide and Ghrelin Promotes Brain and Peripheral Energy Metabolism in the R6/2 Mouse Model of Huntington’s Disease". Scientific Reports (2018): https://doi.org/10.1038/s41598-018-27121-w.
    10.1038/s41598-018-27121-w
  9. A.I. Duarte; M.S. Santos; C.R. Oliveira; P.I. Moreira. "Brain insulin signalling, glucose metabolism and females' reproductive aging: A dangerous triad in Alzheimer's disease". Neuropharmacology (2018): https://doi.org/10.1016/j.neuropharm.2018.01.044.
    10.1016/j.neuropharm.2018.01.044
  10. Sjögren M; Duarte AI; McCourt AC; Shcherbina L; Wierup N; Björkqvist M. "Ghrelin rescues skeletal muscle catabolic profile in the R6/2 mouse model of Huntington's disease.". Scientific reports (2017): http://europepmc.org/abstract/med/29066728.
    10.1038/s41598-017-13713-5
  11. Candeias E; Sebastião I; Cardoso S; Carvalho C; Santos MS; Oliveira CR; Moreira PI; Duarte AI. "Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats.". Molecular neurobiology (2017): http://europepmc.org/abstract/med/28573460.
    10.1007/s12035-017-0622-3
  12. Luana Naia; Teresa Cunha-Oliveira; Joana Rodrigues; Tatiana R. Rosenstock; Ana Oliveira; Márcio Ribeiro; Catarina Carmo; et al. "Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease". The Journal of Neuroscience 37 10 (2017): 2776-2794. https://doi.org/10.1523%2Fjneurosci.2006-14.2016.
    10.1523/JNEUROSCI.2006-14.2016
  13. Candeias, E.; Duarte, A.I.; Sebastião, I.; Fernandes, M.A.; Plácido, A.I.; Carvalho, C.; Correia, S.; et al. "Middle-Aged Diabetic Females and Males Present Distinct Susceptibility to Alzheimer Disease-like Pathology". Molecular Neurobiology (2016): 1-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-84991075553&partnerID=MN8TOARS.
    10.1007/s12035-016-0155-1
  14. Naia, L.; Ribeiro, M.; Rodrigues, J.; Duarte, A.I.; Lopes, C.; Rosenstock, T.R.; Hayden, M.R.; Rego, A.C.. "Insulin and IGF-1 regularize energy metabolites in neural cells expressing full-length mutant huntingtin". Neuropeptides 58 (2016): 73-81. http://www.scopus.com/inward/record.url?eid=2-s2.0-84957398906&partnerID=MN8TOARS.
    10.1016/j.npep.2016.01.009
  15. González-Burgos, E.; Duarte, A.I.; Carretero, M.E.; Moreira, P.I.; Gómez-Serranillos, M.P.. "Kaurane diterpenes as mitochondrial alterations preventive agents under experimental oxidative stress conditions". Pharmaceutical Biology 54 4 (2016): 705-711. http://www.scopus.com/inward/record.url?eid=2-s2.0-84960361628&partnerID=MN8TOARS.
    10.3109/13880209.2015.1072829
  16. Rato, L.; Alves, M.G.; Duarte, A.I.; Santos, M.S.; Moreira, P.I.; Cavaco, J.E.; Oliveira, P.F.. "Testosterone deficiency induced by progressive stages of diabetes mellitus impairs glucose metabolism and favors glycogenesis in mature rat Sertoli cells". International Journal of Biochemistry and Cell Biology 66 (2015): 1-10. http://www.scopus.com/inward/record.url?eid=2-s2.0-84936877372&partnerID=MN8TOARS.
    10.1016/j.biocel.2015.07.001
  17. Carvalho, C.; Correia, S.C.; Cardoso, S.; Plácido, A.I.; Candeias, E.; Duarte, A.I.; Moreira, P.I.. "The role of mitochondrial disturbances in Alzheimer, Parkinson and Huntington diseases". Expert Review of Neurotherapeutics 15 8 (2015): 867-884. http://www.scopus.com/inward/record.url?eid=2-s2.0-84937838385&partnerID=MN8TOARS.
    10.1586/14737175.2015.1058160
  18. Plácido, A.I.; Pereira, C.M.F.; Duarte, A.I.; Candeias, E.; Correia, S.C.; Carvalho, C.; Cardoso, S.; Oliveira, C.R.; Moreira, P.I.. "Modulation of endoplasmic reticulum stress: An opportunity to prevent neurodegeneration?". CNS and Neurological Disorders - Drug Targets 14 4 (2015): 518-533. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929628537&partnerID=MN8TOARS.
  19. Rato, L.; Duarte, A.I.; Tomás, G.D.; Santos, M.S.; Moreira, P.I.; Socorro, S.; Cavaco, J.E.; Alves, M.G.; Oliveira, P.F.. "Pre-diabetes alters testicular PGC1-a/SIRT3 axis modulating mitochondrial bioenergetics and oxidative stress". Biochimica et Biophysica Acta - Bioenergetics 1837 3 (2014): 335-344. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892411578&partnerID=MN8TOARS.
    10.1016/j.bbabio.2013.12.008
  20. Plácido, A.I.; Pereira, C.M.F.; Duarte, A.I.; Candeias, E.; Correia, S.C.; Santos, R.X.; Carvalho, C.; et al. "The role of endoplasmic reticulum in amyloid precursor protein processing and trafficking: Implications for Alzheimer's disease". Biochimica et Biophysica Acta - Molecular Basis of Disease 1842 9 (2014): 1444-1453. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903458925&partnerID=MN8TOARS.
    10.1016/j.bbadis.2014.05.003
  21. Santos, R.X.; Correia, S.C.; Alves, M.G.; Oliveira, P.F.; Cardoso, S.; Carvalho, C.; Duarte, A.I.; Santos, M.S.; Moreira, P.I.. "Insulin therapy modulates mitochondrial dynamics and biogenesis, autophagy and tau protein phosphorylation in the brain of type 1 diabetic rats". Biochimica et Biophysica Acta - Molecular Basis of Disease 1842 7 (2014): 1154-1166. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899789863&partnerID=MN8TOARS.
    10.1016/j.bbadis.2014.04.011
  22. Cardoso, S.; Correia, S.; Carvalho, C.; Candeias, E.; Plácido, A.I.; Duarte, A.I.; Seiça, R.M.; Moreira, P.I.. "Perspectives on mitochondrial uncoupling proteins-mediated neuroprotection". Journal of Bioenergetics and Biomembranes 47 1-2 (2014): 119-131. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922536968&partnerID=MN8TOARS.
    10.1007/s10863-014-9580-x
  23. Lopes, C.; Ribeiro, M.; Duarte, A.I.; Humbert, S.; Saudou, F.; Pereira De Almeida, L.; Hayden, M.; Rego, A.C.. "IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice". Molecular Neurobiology 49 3 (2014): 1126-1142. http://www.scopus.com/inward/record.url?eid=2-s2.0-84902546185&partnerID=MN8TOARS.
    10.1007/s12035-013-8585-5
  24. Sebastião, I.; Candeias, E.; Santos, M.S.; de Oliveira, C.R.; Moreira, P.I.; Duarte, A.I.. "Insulin as a bridge between type 2 diabetes and alzheimer disease - how anti-diabetics could be a solution for dementia". Frontiers in Endocrinology 5 JUL (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84905437740&partnerID=MN8TOARS.
    10.3389/fendo.2014.00110
  25. Naia, L.; Ferreira, I.L.; Cunha-Oliveira, T.; Duarte, A.I.; Ribeiro, M.; Rosenstock, T.R.; Laço, M.N.; et al. "Activation of IGF-1 and Insulin Signaling Pathways Ameliorate Mitochondrial Function and Energy Metabolism in Huntington’s Disease Human Lymphoblasts". Molecular Neurobiology 51 1 (2014): 331-348. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938698507&partnerID=MN8TOARS.
    10.1007/s12035-014-8735-4
  26. Duarte, A.I.; Candeias, E.; Correia, S.C.; Santos, R.X.; Carvalho, C.; Cardoso, S.; Plácido, A.; et al. "Crosstalk between diabetes and brain: Glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration". Biochimica et Biophysica Acta - Molecular Basis of Disease 1832 4 (2013): 527-541. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873306844&partnerID=MN8TOARS.
    10.1016/j.bbadis.2013.01.008
  27. Correia, S.C.; Carvalho, C.; Cardoso, S.; Santos, R.X.; Plácido, A.I.; Candeias, E.; Duarte, A.I.; Moreira, P.I.. "Defective HIF signaling pathway and brain response to hypoxia in neurodegenera-tive diseases: Not an “Iffy” question!". Current Pharmaceutical Design 19 38 (2013): 6809-6822. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884829985&partnerID=MN8TOARS.
  28. González-Burgos, E.; Duarte, A.I.; Carretero, M.E.; Moreira, P.I.; Gómez-Serranillos, M.P.. "Mitochondrial-targeted protective properties of isolated diterpenoids from sideritis spp. in response to the deleterious changes induced by H 2O2". Journal of Natural Products 76 5 (2013): 933-938. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878260967&partnerID=MN8TOARS.
    10.1021/np400118d
  29. Cardoso, S.; Correia, S.C.; Santos, R.X.; Carvalho, C.; Candeias, E.; Duarte, A.I.; Plácido, A.I.; Santos, M.S.; Moreira, P.I.. "Hyperglycemia, hypoglycemia and dementia: Role of mitochondria and uncoupling proteins". Current Molecular Medicine 13 4 (2013): 586-601. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876735551&partnerID=MN8TOARS.
    10.2174/1566524011313040010
  30. Silva, A.C.; Almeida, S.; Laço, M.; Duarte, A.I.; Domingues, J.; Oliveira, C.R.; Januário, C.; Rego, A.C.. "Mitochondrial respiratory chain complex activity and bioenergetic alterations in human platelets derived from pre-symptomatic and symptomatic huntington's disease carriers". Mitochondrion 13 6 (2013): 801-809. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887018742&partnerID=MN8TOARS.
    10.1016/j.mito.2013.05.006
  31. Candeias, E.; Duarte, A.I.; Carvalho, C.; Correia, S.C.; Cardoso, S.; Santos, R.X.; Plácido, A.I.; Perry, G.; Moreira, P.I.. "The impairment of insulin signaling in Alzheimer's disease". IUBMB Life 64 12 (2012): 951-957. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870197271&partnerID=MN8TOARS.
    10.1002/iub.1098
  32. Duarte, A.I.; Moreira, P.I.; Oliveira, C.R.. "Insulin in central nervous system: More than just a peripheral hormone". Journal of Aging Research 2012 (2012): http://www.scopus.com/inward/record.url?eid=2-s2.0-84868282388&partnerID=MN8TOARS.
    10.1155/2012/384017
  33. Rato, L.; Alves, M.G.; Socorro, S.; Duarte, A.I.; Cavaco, J.E.; Oliveira, P.F.. "Metabolic regulation is important for spermatogenesis". Nature Reviews Urology 9 6 (2012): 330-338. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862208844&partnerID=MN8TOARS.
    10.1038/nrurol.2012.77
  34. Correia, S.C.; Santos, R.X.; Cardoso, S.; Carvalho, C.; Candeias, E.; Duarte, A.I.; Plácido, A.I.; Santos, M.S.; Moreira, P.I.. "Alzheimer disease as a vascular disorder: Where do mitochondria fit?". Experimental Gerontology 47 11 (2012): 878-886. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867725518&partnerID=MN8TOARS.
    10.1016/j.exger.2012.07.006
  35. Duarte, A.I.; Petit, G.H.; Ranganathan, S.; Li, J.-Y.; Oliveira, C.R.; Brundin, P.; Björkqvist, M.; Rego, A.C.. "IGF-1 protects against diabetic features in an in vivo model of Huntington's disease". Experimental Neurology 231 2 (2011): 314-319. http://www.scopus.com/inward/record.url?eid=2-s2.0-80052520685&partnerID=MN8TOARS.
    10.1016/j.expneurol.2011.06.016
  36. Rosenstock, T.R.; Duarte, A.I.; Rego, A.C.. "Mitochondrial-associated metabolic changes and neurodegeneration in Huntington's disease - from clinical features to the bench". Current Drug Targets 11 10 (2010): 1218-1236. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957993152&partnerID=MN8TOARS.
  37. Santos, R.X.; Cardoso, S.; Silva, S.; Correia, S.; Carvalho, C.; Crisóstomo, J.; Rodrigues, L.; et al. "Food deprivation promotes oxidative imbalance in rat brain". Journal of Food Science 74 1 (2009): http://www.scopus.com/inward/record.url?eid=2-s2.0-58649112769&partnerID=MN8TOARS.
    10.1111/j.1750-3841.2008.00982.x
  38. Moreira, P.I.; Duarte, A.I.; Santos, M.S.; Rego, A.C.; Oliveira, C.R.. "An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease". Journal of Alzheimer's Disease 16 4 (2009): 741-761. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649687039&partnerID=MN8TOARS.
    10.3233/JAD-2009-0972
  39. Correia, S.; Carvalho, C.; Santos, M.S.; Proença, T.; Nunes, E.; Duarte, A.I.; Monteiro, P.; et al. "Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes". Medicinal Chemistry 4 4 (2008): 358-364. http://www.scopus.com/inward/record.url?eid=2-s2.0-50049125341&partnerID=MN8TOARS.
    10.2174/157340608784872299
  40. Duarte, A.I.; Santos, P.; Oliveira, C.R.; Santos, M.S.; Rego, A.C.. "Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3ß signaling pathways and changes in protein expression". Biochimica et Biophysica Acta - Molecular Cell Research 1783 6 (2008): 994-1002. http://www.scopus.com/inward/record.url?eid=2-s2.0-43549087343&partnerID=MN8TOARS.
    10.1016/j.bbamcr.2008.02.016
  41. Duarte, A.I.; Proença, T.; Oliveira, C.R.; Santos, M.S.; Rego, A.C.. "Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress". Diabetes 55 10 (2006): 2863-2870. http://www.scopus.com/inward/record.url?eid=2-s2.0-33750882488&partnerID=MN8TOARS.
    10.2337/db06-0030
  42. Silva, V.S.; Duarte, A.I.; Rego, A.C.; Oliveira, C.R.; Gonçalves, P.P.. "Effect of chronic exposure to aluminium on isoform expression and activity of rat (Na+/K+)ATPase". Toxicological Sciences 88 2 (2005): 485-494. http://www.scopus.com/inward/record.url?eid=2-s2.0-27944510677&partnerID=MN8TOARS.
    10.1093/toxsci/kfi324
  43. Duarte, A.I.; Santos, M.S.; Oliveira, C.R.; Rego, A.C.. "Insulin neuroprotection against oxidative stress in cortical neurons - Involvement of uric acid and glutathione antioxidant defenses". Free Radical Biology and Medicine 39 7 (2005): 876-889. http://www.scopus.com/inward/record.url?eid=2-s2.0-33644623231&partnerID=MN8TOARS.
    10.1016/j.freeradbiomed.2005.05.002
  44. Monteiro, P.; Duarte, A.I.; Gonçalves, L.M.; Providência, L.A.. "Valsartan improves mitochondrial function in hearts submitted to acute ischemia". European Journal of Pharmacology 518 2-3 (2005): 158-164. http://www.scopus.com/inward/record.url?eid=2-s2.0-23644446746&partnerID=MN8TOARS.
    10.1016/j.ejphar.2005.06.013
  45. Monteiro, P.; Duarte, A.I.; Gonçalves, L.M.; Moreno, A.; Provid^ncia, L.A.. "Protective effect of trimetazidine on myocardial mitochondrial function in an ex-vivo model of global myocardial ischemia". European Journal of Pharmacology 503 1-3 (2004): 123-128. http://www.scopus.com/inward/record.url?eid=2-s2.0-7444267898&partnerID=MN8TOARS.
    10.1016/j.ejphar.2004.09.003
  46. Carreira, R.; Duarte, A.; Monteiro, P.; Sancha Santos, M.; Rego, A.C.; Oliveira, C.R.; Gonçalves, L.M.; Providência, L.A.. "Carvedilol protects ischemic cardiac mitochondria by preventing oxidative stress | O carvedilol protege mitocôndrias cardíacas isquémicas de lesões induzidas por stress oxidativo". Revista Portuguesa de Cardiologia 23 11 (2004): 1447-1455. http://www.scopus.com/inward/record.url?eid=2-s2.0-11244328526&partnerID=MN8TOARS.
  47. Duarte, A.I.; Santos, M.S.; Seiça, R.; Oliveira, C.R.. "Oxidative stress affects synaptosomal ¿-aminobutyric acid and glutamate transport in diabetic rats: The role of insulin". Diabetes 53 8 (2004): 2110-2116. http://www.scopus.com/inward/record.url?eid=2-s2.0-3242787235&partnerID=MN8TOARS.
    10.2337/diabetes.53.8.2110
  48. Pereira, C.; Agostinho, P.; Moreira, P.I.; Duarte, A.I.; Santos, M.S.; Oliveira, C.R.. "Neuroprotection strategies: Effect of vinpocetinein in vitro oxidative stress models | Estratégias de neuroprotecção: Efeito da vimpocetina em modelos in vitro de stresse oxidativo". Acta Medica Portuguesa 16 6 (2003): 401-406. http://www.scopus.com/inward/record.url?eid=2-s2.0-9644310235&partnerID=MN8TOARS.
  49. Monteiro, P.; Duarte, A.; Moreno, A.; Gonçalves, L.; Providência, L.A.. "Pyruvate improves mitochondrial bioenergetics in an ex-vivo animal model of myocardial ischemia | O piruvato melhora a energética mitocondrial num modelo animal ex-vivo de isquemia miocárdica global". Revista Portuguesa de Cardiologia 22 1 (2003): 79-88. http://www.scopus.com/inward/record.url?eid=2-s2.0-0347295997&partnerID=MN8TOARS.
  50. Monteiro, P.; Duarte, A.I.; Moreno, A.; Gonçalves, L.M.; Providência, L.A.. "Carvedilol improves energy production during acute global myocardial ischaemia". European Journal of Pharmacology 482 1-3 (2003): 245-253. http://www.scopus.com/inward/record.url?eid=2-s2.0-0344253727&partnerID=MN8TOARS.
    10.1016/j.ejphar.2003.09.042
  51. Duarte, A.I.; Santos, M.S.; Seiça, R.; De Oliveira, C.R.. "Insulin affects synaptosomal GABA and glutamate transport under oxidative stress conditions". Brain Research 977 1 (2003): 23-30. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037684715&partnerID=MN8TOARS.
    10.1016/S0006-8993(03)02679-9
  52. Santos, M.S.; Duarte, A.I.; Moreira, P.I.; Oliveira, C.R.. "Synaptosomal response to oxidative stress: Effect of vinpocetine". Free Radical Research 32 1 (2000): 57-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033988559&partnerID=MN8TOARS.
  53. Santos, M.S.; Duarte, A.I.; Matos, M.J.; Proença, T.; Seiça, R.; Oliveira, C.R.. "Synaptosomes isolated from Goto-Kakizaki diabetic rat brain exhibit increased resistance to oxidative stress: Role of vitamin E". Life Sciences 67 25 (2000): 3061-3073. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034634237&partnerID=MN8TOARS.
  54. Duarte, A.; Santos, M.; Seiça, R.; Resende De Oliveira, C.. "Effect of oxidative stress on the uptake of GABA and glutamate in synaptosomes isolated from diabetic rat brain". Neuroendocrinology 72 3 (2000): 179-186. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033761028&partnerID=MN8TOARS.
Artigo em revista (magazine)
  1. Duarte AI. "A nossa capacidade de aprender é ilimitada?", Tech & Science section of the Portuguese web-based newspaper: www.noticias.sapo.pt, 2012, http://noticias.sapo.pt/tec_ciencia/artigo/a-nossa-capacidade-de-aprender-e_5055.html.
Capítulo de livro
  1. Duarte AI; Sebastião I, Candeias E, Santos MS, Oliveira CR, Moreira PI, Duarte AI. Autor correspondente: Duarte AI. "Unpuzzling the co-morbid type 2 diabetes and hypertension-related cognitive dysfunction and stroke". In Neuroprotective Therapy for Stroke and Ischemic Disease, editado por Lapchak P, Zhang J, Eds, 711-732. Springer Editors, 2017.
    Publicado
  2. Duarte AI; Santos RX, Correia SC, Cardoso S, Carvalho C, Candeias E, Plácido A, Duarte AI, Santos MS, Moreira PI. "Role of mitochondria and oxidative stress in Parkinson's disease". In Role of oxidative stress in chronic diseases, editado por Dichi I, Breganó JW, Simão ANC, Cecchini R, Eds, 521-548. CRC Press Taylor and Francis Group, 2014.
    Publicado
  3. Duarte AI; Duarte AI, Candeias E, Correia SC, Santos RX, Carvalho C, Cardoso S, Plácido AI, Santos MS, Oliveira CR, Moreira PI. "The Janus face of insulin in brain". In Metabolic Syndrome and Neurological Disorders, 85-113. John Wiley & Sons Ltd, 2013.
    Publicado
Edição de livro
  1. Duarte AI. Influence of oxidative stress and type 2 diabetes mellitus on neuronal function and metabolism – The neuroprotective role of insulin. Beau-Bassin, Maurícias: VDM Publishing House Ltd.. 2010.
    Publicado
Poster em conferência
  1. Duarte AI; Daniela F Silva*, Débora Mena*, Inês N Alves*, Diane E Vaz, Pedro F Monteiro, Paula I Moreira, Ana I Duarte. "EFFECT OF PERIPHERAL ADMINISTRATION OF EVOLOCUMAB ON CEREBRAL CORTEX OF MIDDLE-AGED RATS AT HIGH CARDIOVASCULAR RISK.". Trabalho apresentado em 15th International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD2021) – Virtual Conference, 2021.
    n/a
  2. Duarte AI; Débora Mena, Inês N Alves, Marie Sjögren, Daniela F Silva, Catarina R Oliveira, Paula I Moreira. "DUAL ADMINISTRATION OF LIRAGLUTIDE AND GHRELIN IMPROVES BRAIN MITOCHONDRIAL ENERGY METABOLISM IN THE R6/2 MOUSE MODEL FOR HUNTINGTON´S DISEASE.". Trabalho apresentado em 15th International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD2021) – Virtual Conference, 2021.
    n/a
  3. Duarte AI; Silva FSG, Cunha-Oliveira T, Mena D, Sardão VA, Duarte AI, Oliveira PJ. "UNRAVELING GLYCOLIC PATHWAYS ON AMYOTROPHIC LATERAL SCLEROSIS PATIENTS PRESENTING MUTANT SOD1 OR UNKNOWN MUTATIONS". Trabalho apresentado em 15th International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD2021) – Virtual Conference, 2021.
    n/a
  4. Duarte AI; Mena D, Alves IN, Sjögren M, Silva DF, Oliveira CR, Moreira PI, Björkqvist M, Duarte AI.. "Co-administration of liraglutide and ghrelin improves brain mitochondrial energy metabolism in the R6/2 mouse for Huntington’s disease". Trabalho apresentado em Congresso SPDMov 2020 ¿ Doença de Huntington (Online Forum), 2020.
  5. Duarte AI; Silva DF, Mena D, Sjögren M, Alves IN, Oliveira CR, Moreira PI, Björkqvist M, Duarte AI. "Co-administration of liraglutide and ghrelin stimulates brain cortical pentose phosphate pathway and Krebs cycle in R6/2 mouse for Huntington’s disease.". Trabalho apresentado em Congresso SPDMov 2020 ¿ Doença de Huntington (Online Forum), 2020.
  6. Duarte AI; Alves IN, Mena D, Sjögren M, Silva DF, Oliveira CR, Moreira PI, Björkqvist M, Duarte AI. "Dual treatment with liraglutide and ghrelin improves brain cortical oxidative stress and cholesterol metabolism in the R6/2 mouse for Huntington’s disease.". Trabalho apresentado em Congresso SPDMov 2020 ¿ Doença de Huntington (Online Forum), 2020.
  7. Duarte AI; Mena D*, Alves IN*, Silva DF, Vaz DE, Oliveira CR, Candeias E, Oliveira CR, Monteiro PF, Moreira PI, Duarte AI. "Diet-induced high cardiovascular risk compromises brain hippocampal metabolism and long-term spatial memory in middle-aged male rats. (Presented as a poster plus a flash talk)". Trabalho apresentado em European Society for Clinical Investigation Virtual Meeting 2020 – COVID19 Edition., 2020.
    n/a
  8. Duarte AI; Mena D, Alves IN, Sjögren M, Silva DF, Oliveira CR, Moreira PI, Björkqvist M, Duarte AI. "Co-administration of liraglutide and ghrelin ameliorates brain mitochondrial energy metabolism in the R6/2 mouse model for Huntington’s disease. (Presented as a poster plus a short talk)". Trabalho apresentado em European Society for Clinical Investigation Virtual Meeting 2020 – COVID19 Edition, 2020.
    n/a
  9. Duarte AI; Alves IN, Mena D, Silva DF, Seiça R, Oliveira CR, Duarte AI, Moreira PI. "Type 2 diabetes mitigates brain cortical energy metabolism in middle-aged female rats. (Presented as a poster plus a flash talk; received a prize for best Flash talk/poster presentation).". Trabalho apresentado em European Society for Clinical Investigation Virtual Meeting 2020 – COVID19 Edition, 2020.
  10. Duarte AI; Silva DF, Alves IN, Mena D, Vaz DE, Monteiro PF, Moreira PI, Duarte AI. "The neuroprotective effects of peripheral treatment with Evolocumab in middle-aged rat at high cardiovascular risk. (Presented as a flash talk plus poster).". Trabalho apresentado em European Society for Clinical Investigation Virtual Meeting 2020 – COVID19 Edition., 2020.
    n/a
  11. Duarte AI. "The sexual dimorphism in brain glucose (energy) metabolism in middle-aged type 2 diabetic rats.". Trabalho apresentado em FENS Virtual Forum of Neuroscience 2020. Glasgow, UK, 2020.
    n/a
  12. Duarte AI. "DIET-INDUCED HIGH CARDIOVASCULAR RISK IMPAIRS BRAIN HIPPOCAMPAL METABOLISM AND LONG-TERM SPATIAL MEMORY IN MIDDLE-AGED MALE RATS.". Trabalho apresentado em 15th International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD2021) – Virtual Conference, 2020.
    n/a
  13. Duarte AI; Alves IN, Mena D, Silva DF, Seiça R, Oliveira CR, Moreira PI, Duarte AI. "Type 2 diabetes mitigates brain cortical energy metabolism in middle-aged female rats.". Trabalho apresentado em 1st Meeting of CIBB – Center for Innovative Biomedicine & Biotechnology, 2019.
  14. Duarte AI; Mena D, Alves IN, Sjögren M, Silva DF, Oliveira CR, Moreira PI, Björkqvist M, Duarte AI. "Dual therapy with liraglutide and ghrelin improves brain mitochondrial energy metabolism in the R6/2 mouse model for Huntington’s disease". Trabalho apresentado em 1st Meeting of CIBB – Center for Innovative Biomedicine & Biotechnology, 2019.
  15. Duarte AI; Duarte AI, Alves IN, Mena D, Silva DF, Candeias E, Oliveira CR, Monteiro PF, Moreira PI. "Diet-induced high cardiovascular risk impairs brain hippocampal metabolism and long-term spatial memory in middle-aged male rats". Trabalho apresentado em 1st Meeting of CIBB – Center for Innovative Biomedicine & Biotechnology, 2019.
  16. Duarte AI; Marinho D, Martinho V, Duarte AI, Ferreira IL, Rego AC. "Mitochondrial function and behavior modifications in cell and animal models of Alzheimer's disease: role of class I HDACis". Trabalho apresentado em 1st Meeting of CIBB – Center for Innovative Biomedicine & Biotechnology, 2019.
  17. Duarte AI; Marinho D, Martinho V, Duarte AI, Ferreira IL, Rego AC. "Role of class I histone deacetylase inhibitors in cell and animal models of Alzheimer’s disease. Lisboa, Portugal, May 30th - June 1st 2019.". Trabalho apresentado em XVI Meeting of the Portuguese Society of Neurosciences, 2019.
  18. Duarte AI; Duarte AI, Alves IN, Mena D, Candeias E, Oliveira CR, Monteiro PF, Moreira PI.. "Diet-induced high cardiovascular risk impairs brain hippocampal metabolism and long-term spatial memory in middle-aged male rats. Coimbra, Portugal. May 22nd-24th 2019.". Trabalho apresentado em ESCI2019 - 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
  19. Duarte AI; Mena D, Alves IN, Sjögren M, Oliveira CR, Moreira PI, Björkqvist M, Duarte AI. "Dual administration of liraglutide and ghrelin recovers brain mitochondrial energy metabolism in the R6/2 mouse for Huntington’s disease". Trabalho apresentado em ESCI2019 - 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
    10.1055/s-0039-1683689
  20. Duarte AI. "Profiling of proteostasis, mitochondrial and redox markers in the brain and liver from the R6/2 Huntington’s disease mouse model". Trabalho apresentado em ESCI2019 - 53rd Annual Scientific Meeting of the European Society for Clinical Investigation, 2019.
  21. Duarte AI. "Brain mitochondrial metabolism is stimulated in middle-aged type 2 diabetic female rats". Trabalho apresentado em AD/PDTM 2019 - 14th International Conference on Alzheimer's and Parkinson's Diseases, 2019.
  22. Duarte AI; Duarte AI*, Mena D*, Alves IN, Sjögren M, Oliveira CR, Moreira PI, Björkqvist M. "The role of liraglutide and ghrelin on brain energy metabolism in the R6/2 mouse for Huntington’s disease". Trabalho apresentado em AD/PDTM 2019 - 14th International Conference on Alzheimer's and Parkinson's Diseases, 2019.
  23. Duarte AI; Pereira SP, Tavares LC, Duarte AI, Baldeiras I, Cunha-Oliveira T, Santos MS, Maloyan A, Moreno AJ, Cox LA, Li C, Nat. "IUGR Remodels Fetal Cardiac Left Ventricular (LV) Mitochondria in Baboons". Trabalho apresentado em 66th Annual Meeting of the European Society for Reproductive Investigation (SRI2019), 2019.
  24. Duarte AI; Alves IN, Mena D, Seiça R, Oliveira CR, Moreira PI, Duarte AI. "Female gender stimulates brain mitochondrial metabolism in middle-aged type 2 diabetic rats". Trabalho apresentado em 32ª. Reunião do Grupo de Estudos Envelhecimento Cerebral e Demência (GEECD), 2018.
  25. Duarte AI; Mena D, Alves IN, Sjögren M, Oliveira CR, Moreira PI, Björkqvist M, Duarte AI. "Effects of dual administration of liraglutide and ghrelin on brain mitochondrial metabolism in the R6/2 mouse for Huntington’s disease". Trabalho apresentado em 32ª. Reunião do Grupo de Estudos Envelhecimento Cerebral e Demência (GEECD), 2018.
  26. Duarte AI; Duarte AI, Sjögren M, Mena D, Alves IN, Santos MS, Oliveira CR, Moreira PI, Björkqvist M. "Effects of dual administration of liraglutide and ghrelin on brain mitochondrial metabolism in the R6/2 mouse". Trabalho apresentado em 10th European Huntington Disease Network (EHDN) Plennary Meeting 2018. Vienna, Austria, 2018.
  27. Duarte AI; Pinho BR, Duarte AI, Almeida LM, Canas PM, Moreira PI, Murphy MP, Oliveira JMA. "Targeting mitochondria in Huntington’s disease: effects of MitoQ in the R6/2 mouse model". Trabalho apresentado em MitoPorto – Advances in Mitochondrial Research – International Symposium, 2018.
  28. Duarte AI; Rato L, Diniz A, Alves MG, Candeias E, Duarte AI, Moreira PI, Silva BM, Oliveira PF. "Type 2 diabetes mellitus compromises the epididymal SIRT1/PGC-1a/SIRT3 axis predisposing to oxidative environment.". Trabalho apresentado em I Novel Therapeutic Strategies for Noncommunicable Diseases (NoTeS) Congress, 2018.
  29. Duarte AI; Pinho BR, Duarte AI, Almeida LM, Canas PM, Moreira PI, Murphy MP, Oliveira JMA. "Effects of MitoQ on behavioural and biochemical phenotypes of a Huntington’s disease mouse model". Trabalho apresentado em 10th European Huntington Disease Network (EHDN) Plennary Meeting 2018, 2018.
  30. Duarte AI; Pereira SP, Nijland MJ, Tavares LC, Duarte AI, Baldeiras I, Cunha-Oliveira T, Santos MS, Maloyan A, Moreno AJ, Cox L. "Effects of moderate global maternal nutrient reduction on fetal baboon cardiac left ventricular mitochondria". Trabalho apresentado em MitoPorto - Advances in Mitochondrial Research – International Symposium, 2017.
  31. Duarte AI. "Peripheral exendin-4 treatment restores brain cortical glucose metabolism in type 2 diabetic rats". Trabalho apresentado em MitoPorto – Advances in Mitochondrial Research – International Symposium, 2017.
  32. Duarte AI; Duarte AI*, Alves IN*, Candeias E, Sebastião I, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Changes in brain glucose metabolism render middle-aged females less vulnerable to chronic type 2 diabetes-related Alzheimer disease.". Trabalho apresentado em XV Meeting of the Portuguese Society of Neurosciences, 2017.
  33. Duarte AI; Pereira SP, Tavares LC, Duarte AI, Cunha-Oliveira T, Santos MS, Baldeiras I, Clarke G, Moreno AJ, Cox LA, Nathaniels. "Influence of maternal nutrition during pregnancy on fetal cardiac mitochondria outcome". Trabalho apresentado em XIX Meeting of the Portuguese Biochemical Society, 2016.
  34. Duarte AI; Duarte AI, Sjögren M, Santos MS, Oliveira CR, Moreira PI, Björkqvist M. "Effects of peripheral (co-)administration of liraglutide and ghrelin in the R6/2 mouse brain function". Trabalho apresentado em 9th European Huntington Disease Network (EHDN) Plennary Meeting 2016, 2016.
  35. Duarte AI; Sjögren M, Duarte AI, McCourt AC, Shcherbina L, Wierup N, Björkqvist M. "The effect of ghrelin administration in the R6/2 mouse model of Huntington’s disease". Trabalho apresentado em 9th European Huntington Disease Network (EHDN) Plennary Meeting 2016, 2016.
  36. Duarte AI; Sjögren M, Duarte AI, McCourt AC, Shcherbina L, Wierup N, Björkqvist M. "The effect of ghrelin administration in the R6/2 mouse model of Huntington’s disease". Trabalho apresentado em 10th FENS Forum of Neuroscience, 2016.
  37. Duarte AI; Duarte AI, Candeias E, Sebastião I, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Glucose metabolism modulates gender-related diabetic brain susceptibility to Alzheimer disease-like neurodegeneration". Trabalho apresentado em Molecular Biology of Ageing Meeting, 2015.
  38. Duarte AI; Rato L, Alves MG, Duarte AI, Santos MS, Moreira PI, Cavaco JE, Oliveira PF. "Progressive stages of diabetes mellitus induce testosterone deficiency promoting a modulation of Sertoli cell metabolism". Trabalho apresentado em 31st Annual Meeting of ESHRE, 2015.
  39. Duarte AI; Duarte AI, Candeias E, Sebastião I, Plácido AI, Santos RX, Carvalho C, Correia S, Fernandes MA, Seiça R, Santos MS,. "Gender influences type 2 diabetic-related intracellular brain signaling and neurodegeneration markers". Trabalho apresentado em XIV Meeting of the Portuguese Society of Neurosciences, 2015.
  40. Duarte AI; Sebastião I, Candeias E, Santos MS, Oliveira CR, Moreira PI, Duarte AI. "Chronic peripheral administration of exendin-4: does it protect against brain dysfunction and cell death?". Trabalho apresentado em XIV Meeting of the Portuguese Society of Neurosciences, 2015.
  41. Duarte AI; Candeias E, Sebastião I, Machado N, Santos MS, Oliveira CR, Moreira PI, Duarte AI. "Actions of the peripheral anti-type 2 diabetic liraglutide in Alzheimer disease: brain glucose metabolism, neuroinflammation and cognition". Trabalho apresentado em XIV Meeting of the Portuguese Society of Neurosciences, 2015.
  42. Duarte AI; Candeias E, Sebastião I, Machado N, Santos MS, Oliveira CR, Moreira PI, Duarte AI. "Exendin-4 therapy restores brain glucose homeostasis in type 2 diabetic Goto-Kakizaki rats: impact on neuroinflammation and oxidative stress". Trabalho apresentado em XIV Meeting of the Portuguese Society of Neurosciences, 2015.
  43. Duarte AI; Duarte AI, Candeias E, Sebastião I, Carvalho C, Correia S, Plácido AI, Santos RX, Fernandes MA, Seiça R, Santos MS,. "Brain intracellular signaling, oxidative stress and Alzheimer’s disease-related hallmarks upon type 2 diabetes are differentially influenced by gender". Trabalho apresentado em 12th International Conference on Alzheimer’s & Parkinson’s diseases, 2015.
  44. Duarte AI; Candeias E, Sebastião I, Machado N, Santos MS, Oliveira CR, Moreira PI, Duarte AI. "Exendin-4-induced GLP-1 receptor signaling pathways restore autophagy and cognitive function and avoid alzheimer disease like-hallmarks". Trabalho apresentado em 12th International Conference on Alzheimer’s & Parkinson’s diseases, 2015.
  45. Duarte AI; Candeias E, Sebastião I, Machado N, Santos MS, Oliveira CR, Moreira PI, Duarte AI. "Peripheral liraglutide therapy counteracts Alzheimer's disease-related brain changes". Trabalho apresentado em 12th International Conference on Alzheimer’s & Parkinson’s diseases, 2015.
  46. Duarte AI; Sebastião I, Candeias E, Santos MS, Oliveira CR, Moreira PI, Duarte AI. "Chronic peripheral administration of exendin-4: is it advantageous against brain dysfunction and cell death?". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  47. Duarte AI; Candeias E, Sebastião I, Santos MS, Oliveira CR, Moreira PI, Duarte AI. "Peripherally-administered exendin-4 ameliorates type 2 diabetes-associated brain glucose dysmetabolism, neuroinflammation and oxidative stress". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  48. Duarte AI; Pereira SP, Oliveira PJ, Tavares LC, Duarte AI, Santos MS, Baldeiras I, Moreno AJ, Cox LA, Nathanielsz PW, Nijland M. "Implications of maternal nutrient reduction in cardiac mitochondria of fetal non-human primates at 0.6 gestation". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
  49. Duarte AI; Sebastião I, Candeias E, Santos MS, Oliveira CR, Moreira PI, Duarte AI. "Chronic peripheral administration of exendin-4: is it advantageous against brain dysfunction and cell death?". Trabalho apresentado em XII CNC Annual Meeting, 2014.
  50. Duarte AI; Candeias E, Sebastião I, Santos MS, Oliveira CR, Moreira PI, Duarte AI. "Peripherally-administered exendin-4 ameliorates type 2 diabetes-associated brain glucose dysmetabolism, neuroinflammation and oxidative stress". Trabalho apresentado em XII CNC Annual Meeting, 2014.
  51. Duarte AI; Pereira SP, Oliveira PJ, Tavares LC, Duarte AI, Santos MS, Baldeiras I, Moreno AJ, Cox LA, Nathanielsz PW, Nijland M. "Implications of maternal nutrient reduction in cardiac mitochondria of fetal non-human primates at 0.6 gestation". Trabalho apresentado em XII CNC Annual Meeting, 2014.
  52. Duarte AI; Duarte AI, Candeias E, Sebastião I, Correia S, Carvalho C, Plácido AI, Santos RX, Fernandes MA, Seiça R, Santos MS,. "Type 2 diabetic female rat brains are less vulnerable to oxidative stress and AD-related hallmarks: a role for insulin/IGF-1/estrogen signaling?". Trabalho apresentado em XII CNC Annual Meeting, 2014.
  53. Duarte AI; Rato L, Duarte AI, Tomás G, Santos MS, Moreira PI, Socorro S, Cavaco JE, Alves MG, Oliveira PF. "Pre-diabetes disrupts testicular PGC1a/SIRT3 axis prompting oxidative stress". Trabalho apresentado em 18th European Bioenergetics Conference - EBEC2014, 2014.
  54. Duarte AI; Sebastião I, Candeias E, Santos MS, Oliveira CR, Moreira P, Duarte AI. "Chronic peripheral exendin-4 administration protects against type 2 diabetes-associated rat brain apoptosis". Trabalho apresentado em 9th FENS Forum of Neuroscience, 2014.
    10.1158/1538-7445.am2015-1008
  55. Duarte AI; Candeias E, Sebastião I, Santos MS, Oliveira CR, Moreira P, Duarte AI. "Peripheral exendin-4 therapy restores brain glucagon-like peptide-1 receptor-mediated signaling pathways and glucose uptake and metabolism in type 2 diabetic Goto-Kakizaki rats". Trabalho apresentado em 9th FENS Forum of Neuroscience, 2014.
  56. Duarte AI; Duarte AI, Candeias E, Sebastião I, Carvalho C, Correia S, Plácido AI, Santos RX, Fernandes MA, Seiça R, Santos MS,. "Type 2 diabetic female rat brains are less vulnerable to oxidative stress and AD-related hallmarks: a role for insulin/IGF-1/estrogen signaling?". Trabalho apresentado em 9th FENS Forum of Neuroscience, 2014.
  57. Lopes C, Ribeiro M, Duarte AI, Humbert S, Saudou F, Almeida LP, Hayden M, Rego AC. "IGF-1 intranasal administration rescues Huntington’s Disease phenotypes in YAC128 mice". Trabalho apresentado em 28ª. Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência, 2014.
    10.1063/1.1328954
  58. Duarte AI; Candeias E, Duarte AI, Carvalho C, Correia S, Plácido AI, Santos RX, Fernandes MA, Seiça R, Santos MS, Oliveira CR,. "Gender modulates type 2 diabetes progression and development of Alzheimer disease-like hallmarks in adult rat brains". Trabalho apresentado em 4th PF2MUC Symposium, 2013.
  59. Duarte AI; Candeias E, Duarte AI, Correia S, Carvalho C, Fernandes MA, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Alzheimer disease hallmarks in adult type 2 diabetic female rat brain: Is oxidative stress the the predecessor?". Trabalho apresentado em Federation of Biochemical European Societies Congress 2013, 2013.
  60. Duarte AI; Rato L, Duarte AI, Alves MG, Santos MS, Moreira PI, Socorro S, Cavaco JE, Oliveira PF. "Testicular mitochondrial bioenergetics is altered in pre-diabetes induced by a high-energy diet in rats". Trabalho apresentado em Federation of Biochemical European Societies Congress 2013, 2013.
  61. Duarte AI; Candeias E, Duarte AI, Carvalho C, Correia S, Fernandes MA, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Adult female rat brain is less prone to Alzheimer disease hallmarks than male brain: the role of insulin/IGF-1 signaling". Trabalho apresentado em XIII Meeting of the Portuguese Neuroscience Society, 2013.
  62. Duarte AI; Naia l, Ferreira IL, Cunha-Oliveira T, Ribeiro M, Duarte AI, Ribeiro MJ, Oliveira CR, Saudou F, Humbert S, Rego AC. "Activation of IR, IGF-1R signaling pathways promote mitochondrial function and energy metabolism in Huntington’s disease human lymphoblasts". Trabalho apresentado em XIII Meeting of the Portuguese Neuroscience Society, 2013.
  63. Duarte AI; Candeias E, Duarte AI, Carvalho C, Correia S, Fernandes MA, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Gender effects in adult rat brains: Type 2 diabetes and Alzheimer disease hallmarks". Trabalho apresentado em 47th Annual Scientific Meeting of the European Society for Clinical Investigation 2013, 2013.
  64. Duarte AI, Candeias E, Correia S, Carvalho C, Fernandes MA, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Type 2 diabetic female rats are less vulnerable to Alzheimer’s disease than males: the role of brain insulin/IGF-1 and estrogen". Trabalho apresentado em 11th International Conference on Alzheimer’s & Parkinson’s diseases, 2013.
    10.18260/1-2--27668
  65. Duarte AI; Candeias E, Duarte AI, Correia S, Carvalho C, Fernandes MA, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Oxidative damage in adult type 2 diabetic females ratbrain precedes the development of Alzheimer disease features". Trabalho apresentado em Reunião Anual da Sociedade Portuguesa de Diabetologia, 2013.
  66. Duarte AI; Duarte AI, Candeias E, Carvalho C, Correia S, Santos SC, Fernandes MA, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Type 2 diabetes-associated damage in aged rat brain: does gender matter?". Trabalho apresentado em 2nd PF2MUC Symposium, 2012.
  67. Duarte AI; Cunha-Oliveira T, Naia L, Ferreira IL, Rosenstock T, Duarte AI, Ribeiro M, Laço MN, Ribeiro M, Oliveira CR, Saudou F. "Activation of IGF-1 and insulin signaling pathways ameliorate energy metabolism and mitochondrial function in Huntington’s disease human lymphoblasts". Trabalho apresentado em 42nd Annual Meeting of the Society for Neuroscience 2012, 2012.
  68. Duarte AI; González-Burgos E, Duarte AI, Carretero ME, Moreira PI, Gómez-Serranillos MP. "Linearol as natural mitochondria-targeted antioxidant: potential benefits in neurodegenerative diseases". Trabalho apresentado em 16th Society for Free Radical Research International Biennial Meeting, 2012.
  69. Duarte AI; Duarte AI, Candeias E, Correia S, Carvalho C, Santos SC, Fernandes MA, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Type 2 diabetes-associated damage in aged rat brain: does gender matter?". Trabalho apresentado em 8th FENS Forum of European Neuroscience 2012, 2012.
  70. Duarte AI; Candeias E, Duarte AI, Carvalho C, Correia S, Santos SC, Fernandes MA, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Brain damage in mature type 2 diabetic Goto-Kakizaki rat: does gender play a role?". Trabalho apresentado em 8th FENS Forum of European Neuroscience 2012, 2012.
  71. Duarte AI; Lopes CMN, Ribeiro M, Duarte AI, Humbert S, Saudou F, Pereira de Almeida L, Hayden M, Rego AC. "IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice". Trabalho apresentado em 8th FENS Forum of European Neuroscience 2012, 2012.
  72. Duarte AI; Candeias E, Duarte AI, Carvalho C, Correia S, Fernandes MA, Seiça R, Santos MS, Oliveira CR, Moreira PI. "The role of gender in the brain of type 2 diabetic rats". Trabalho apresentado em 25ª. Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência, 2012.
  73. Duarte AI; Lopes C, Ribeiro M, Duarte AI, Humbert S, Saudou F, Almeida LP, Hayden M, Rego AC. "IGF-1 intranasal administration ameliorates Huntington’s disease metabolic profile in YAC128 mice". Trabalho apresentado em V Clinical Biochemistry Workshop, 2012.
  74. Duarte AI; Naia L, Duarte AI, Hayden MR, Oliveira CR, Rego AC. "Insulin and IGF-1 prevent dysfunctional metabolism in cortical neurons from YAC128 mice". Trabalho apresentado em V Clinical Biochemistry Workshop, 2012.
  75. Duarte AI; Naia LC, Duarte AI, Oliveira CR, Rego AC. "Insulin and IGF-1 stimulate intracellular signaling pathways and energy metabolism in Huntington’s disease human peripheral cells". Trabalho apresentado em Sinal 2011 – 5th Annual Meeting on Cell Signaling, 2011.
  76. Duarte AI; Lopes CM, Duarte AI, M. Hayden, Oliveira CR, Rego AC. "Peripheral and cerebral diabetic features in an animal model of Huntington’s disease expressing full-length mutant huntingtin". Trabalho apresentado em Sinal 2011 – 5th Annual Meeting on Cell Signaling, 2011.
  77. Duarte AI; Duarte AI, Petit G, Ranganathan S, Björkqvist M, Li J-Y, Oliveira CR, Brundin P, Rego AC. "Insulin-like growth factor-1 protects against diabetic features in the R6/2 mouse model of Huntington’s disease". Trabalho apresentado em 40th Annual Meeting of the Society for Neuroscience 2010, 2010.
  78. Duarte AI; Duarte AI, Petit G, Ranganathan S, Björkqvist M, Li J-Y, Oliveira CR, Brundin P, Rego AC. "IGF-1 protects against diabetic parameters in an in vivo model of Huntington’s disease". Trabalho apresentado em 6th FENS Forum of European Neuroscience 2010, 2010.
  79. Duarte AI; Duarte AI, Petit G, Ranganathan S, Björkqvist M, Li J-Y, Oliveira CR, Brundin P, Rego AC. "Effect of IGF-1 on diabetic parameters in an in vivo model of Huntington’s disease". Trabalho apresentado em World Congress on Huntington’s Disease, 2009.
  80. Duarte AI; Duarte AI, Ribeiro M, Oliveira CR, Rego AC. "Effect of insulin on oxidative stress and caspase-3 activity in a cellular model of Huntington’s disease". Trabalho apresentado em 11th Meeting of the Portuguese Neuroscience Society, 2009.
  81. Duarte AI; Duarte AI, Ribeiro M, Ferreira IL, Oliveira CR, Rego AC. "Insulin protects from oxidative stress and caspase-3 activation in an in vitro model of Huntington’s disease". Trabalho apresentado em European Huntington’s Disease Network (EHDN) Meeting 2008, 2008.
  82. Duarte AI; Ribeiro M, Ferreira IL, Duarte AI, Oliveira CR, Rego AC. "Detailing oxidative stress features in an in vitro model of Huntington’s disease". Trabalho apresentado em European Huntington’s Disease Network (EHDN) Meeting 2008, 2008.
  83. Duarte AI; Duarte AI, Proença T, Monteiro P, Gonçalves LM, Providência LA, Seiça R, Oliveira CR, Santos MS, Rego AC. "Oxidative stress in type 2 diabetic GK rat retina during aging". Trabalho apresentado em 2007 European Meeting of the Society for Free Radical Research International, 2007.
    10.1158/1538-7445.am2012-1124
  84. Duarte AI; Duarte AI, Santos MS, Santos P, Oliveira CR, Rego AC. "Neuroprotective role of insulin against oxidative stress is mediated by Akt and GSK-3b signaling pathways and changes in protein expression". Trabalho apresentado em IV Reunião Anual do Centro de Neurociências e Biologia Celular, 2006.
  85. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Neuroprotective role of insulin against oxidative stress is mediated by Akt and GSK-3b signaling pathways". Trabalho apresentado em XV Congresso Nacional de Bioquímica, 2006.
  86. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Neuroprotective role of insulin against oxidative stress is mediated by Akt and GSK-3b signaling pathways". Trabalho apresentado em 36th Annual Meeting of the Society for Neuroscience, 2006.
  87. Duarte AI; Monteiro PF, Paiva M, Carreira R, Duarte AI, Gonçalves LM, Providência LA. "Effect of chronic atorvastatin therapy in the mitochondrial function in an ex-vivo animal model of global myocardial ischemia-reperfusion". Trabalho apresentado em World Congress of Cardiology 2006/European Society of Cardiology Congress 2006, 2006.
  88. Duarte AI; Monteiro PF, Paiva M, Carreira R, Duarte AI, Gonçalves LM, Providência LA. "Effect of chronic insulin therapy in the mitochondrial function in an ex-vivo animal model of global myocardial ischemia-reperfusion". Trabalho apresentado em World Congress of Cardiology 2006/European Society of Cardiology Congress 2006, 2006.
  89. Duarte AI; Monteiro PF, Paiva M, Carreira R, Duarte AI, Gonçalves LM, Providência LA. "Effect of chronic metformin therapy in the mitochondrial function in an ex-vivo animal model of global myocardial ischemia-reperfusiong". Trabalho apresentado em World Congress of Cardiology 2006/European Society of Cardiology Congress 2006, 2006.
    10.1109/pgc.2010.5706018
  90. Duarte AI; Monteiro PF, Paiva M, Carreira R, Duarte AI, Gonçalves LM, Providência LA. "Effect of chronic gliclazide therapy in the mitochondrial function in an ex-vivo animal model of global myocardial ischemia-reperfusion". Trabalho apresentado em World Congress of Cardiology 2006/European Society of Cardiology Congress 2006, 2006.
  91. Duarte AI; Duarte AI, Proença T, Santos MS, Seiça R, Oliveira CR, Rego AC. "Retinal degeneration during aging in type-2 diabetic Goto-Kakizaki rats". Trabalho apresentado em 35th Annual Meeting of the Society for Neuroscience, 2005.
  92. Duarte AI; Duarte AI, Proença T, Santos MS, Seiça R, Oliveira CR, Rego AC. "Retinal degeneration upon aging and type 2 diabetes". Trabalho apresentado em 3ª Reunião Anual do Centro de Neurociências e Biologia Celular, 2005.
  93. Duarte AI; Duarte AI, Proença T, Santos MS, Seiça R, Oliveira CR, Rego AC. "Retinal degeneration upon aging and type 2 dabetes". Trabalho apresentado em 9th Meeting of the Portuguese Neuroscience Society, 2005.
  94. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR, Rego AC. "Effect of aging and/or type 2 diabetes in retinal degeneration - involvement of metabolic dysfunction and oxidative stress". Trabalho apresentado em XIV Portuguese Congress of Biochemistry, 2004.
  95. Duarte AI; Duarte AI, Proença T, Santos MS, Oliveira CR, Rego AC. "Protective role of insulin against neuronal metabolic dysfunction induced by oxidative stress". Trabalho apresentado em 2nd Spanish and Portuguese Congress on Free Radicals, 2004.
  96. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Papel protector da insulina contra a disfunção metabólica neuronal induzida pelo stresse oxidativo". Trabalho apresentado em IV Congresso de Investigação em Medicina, 2004.
  97. Duarte AI; Duarte AI, Proença T, Santos MS, Oliveira CR, Rego AC. "Neuroprotective effect of insulin against metabolic dysfunction induced by oxidative stress". Trabalho apresentado em Free Radical School 2004: Free Radicals and Diseases - Gene Expression, Cellular Metabolism and Pathophysiology, 2004.
  98. Duarte AI; Duarte AI, Proença T, Santos MS, Oliveira CR, Rego AC. "Insulin protects against oxidative stress-induced metabolic dysfunction in cultured cortical neurons". Trabalho apresentado em FEBS Postgraduate Course "New molecular strategies to treat neurodegenerative diseases"., 2004.
  99. Duarte AI. "Insulin protects against oxidative stress-induced metabolic dysfunction in cultured cortical neurons". Trabalho apresentado em 4th Forum of the Federation of European Neuroscience Societies Meeting 2004, 2004.
  100. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Insulin protects against metabolic dysfunction induced by oxidative stress in cultured cortical neurons". Trabalho apresentado em VI Portuguese Congress on Free Radicals in Chemistry, Biology and Medicine/1st Luso-Spanish Congress on Free Radicals, 2003.
  101. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Neuroprotection of insulin against oxidative stress in cultured cortical neurons – a role on antioxidant defenses and cellular metabolism?". Trabalho apresentado em 32nd Annual Society for Neuroscience Meeting, 2003.
  102. Duarte AI; Monteiro P, Duarte A, Goncalves L, Providencia LA. "Nitric oxide mediates bradykinin cardioprotective effects". Trabalho apresentado em European Society of Cardiology Congress 2003, 2003.
  103. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Influence of insulin on oxidative stress-mediated metabolic changes in cultured cortical neurons". Trabalho apresentado em 17ª Reunião do Grupo de Estudos em Envelhecimento Cerebral e Demência, 2003.
  104. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Neuroprotection of insulin against oxidative stress in cultured cortical neurons – changes in glutathione redox cycle". Trabalho apresentado em 8th Meeting of the Portuguese Neuroscience Society, 2003.
  105. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Insulin protects cultured cortical neurons from oxidative stress-induced damage.". Trabalho apresentado em Physiological Society Spring Workshop and Hungarian Academy of Sciences-Receptors and Cell Signalling in Oxidative Stress., 2003.
  106. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Can insulin have a neuroprotective role in cultured cortical neurons submitted to oxidative stress?". Trabalho apresentado em Oxygen Club of California Conference – Oxidants and Antioxidants in Biology., 2003.
  107. Duarte AI; Monteiro P, Moura JP, Silva S, Duarte A, Oliveira P, Gonçalves L, Providência LA. "Valsartan: Impact on mitochondrial function in acute ischemia". Trabalho apresentado em IIIèmes Journées Européennes de la Société Française de Cardiologie, 2003.
  108. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Effect of insulin on cultured cortical neurons under metabolic or oxidative stress". Trabalho apresentado em XIII Portuguese Congress of Biochemistry, 2002.
  109. Duarte AI; Duarte A, Santos MS, Seiça R, Oliveira CR. "Insulin modulates GABA and glutamate transport under oxidative stress conditions in diabetic rat brain synaptosomes.". Trabalho apresentado em III Congresso de Investigação em Medicina, 2002.
  110. Duarte AI; Monteiro P, Duarte A, Oliveira P, Gonçalves L, Providência LA. "Influência do piruvato na bioenergética mitocondrial num modelo animal ex-vivo de isquemia miocárdica global". Trabalho apresentado em III Congresso de Investigação em Medicina, 2002.
  111. Duarte AI; Rosa MH, Colito FZ, Moura JP, Duarte A, Monteiro P, Oliveira P, Gonçalves L, Providência LA. "Valsartan: impacto na função mitocondrial cardíaca durante a isquemia aguda". Trabalho apresentado em III Congresso de Investigação em Medicina, 2002.
  112. Duarte AI; Moura JP, Duarte A, Monteiro P, Oliveira P, Gonçalves L, Providência LA. "Os efeitos protectores mitocondriais da bradicinina são dependentes da produção De óxido nítrico". Trabalho apresentado em III Congresso de Investigação em Medicina, 2002.
  113. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Insulin affects synaptosomal GABA and glutamate transport under oxidative stress conditions in diabetic rat brain". Trabalho apresentado em 32nd Annual Society for Neuroscience Meeting, 2002.
  114. Duarte AI; Monteiro P, Silva S, Moura JP, Duarte A, Moreno A, Goncalves L, Providencia LA. "The protective effect of isosorbide dinitrate on cardiac mitochondria during ischemia is not mediated by nitric oxide". Trabalho apresentado em XIII Congress of the European Society of Cardiology, 2002.
  115. Duarte AI; Monteiro P, Moura JP, Silva S, Duarte A, Oliveira PJ, Moreno A, Gonçalves L, Providência LA. "Effects of bradykinin on mitochondrial respiratory chain function in an animal model of global myocardial ischemia". Trabalho apresentado em European Bioenergetics Conference–EBEC 2002, 2002.
  116. Duarte AI; Moura JP, Monteiro P, Silva S, Duarte A, Oliveira PJ, Moreno A, Gonçalves L, Providência LA. "Bradykinin protective effects on cardiac mitochondria are nitric oxide-dependent.". Trabalho apresentado em European Bioenergetics Conference–EBEC 2002, 2002.
  117. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Oxidative stress and glutamate accumulation in diabetic GK rat brain synaptosomes: the role of vitamin E (alpha-tocopherol).". Trabalho apresentado em XIth Biennial Meeting of the Society for the Free Radical Research International., 2002.
  118. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "A idade afecta a susceptibilidade dos sinaptossomas de ratos diabéticos à lesão oxidativa e a actividade das ATPases membranares". Trabalho apresentado em 16ª. Reunião do Grupo de Estudos em Envelhecimento Cerebral e Demência, 2002.
  119. Duarte AI; Monteiro P, Duarte A, Moreno A, Gonçalves L, Providência LA. "Bradikinin improves the energetic status and the respiratory chain’s activity in an ex-vivo model of global myocardial ischemia". Trabalho apresentado em Heart Failure Update 2002, 2002.
  120. Duarte AI; Monteiro PF, Duarte AI, Gonçalves LM, Moreno AJ, Providência LA. "Positive impact of bradikinin on mitochondrial metabolism during acute ischemia–an explanation for its preconditioning effects?". Trabalho apresentado em XIVth World Congress of Cardiology 2002, 2002.
  121. Duarte AI; Monteiro PF, Duarte AI, Gonçalves LM, Moreno AJ, Providência LA. "Impact of pyruvate on the mitochondrial function and energetics in an animal model of ex-vivo global myocardial ischemia". Trabalho apresentado em XIVth World Congress of Cardiology 2002, 2002.
  122. Duarte AI; Monteiro P, Duarte A, Moreno A, Gonçalves A, Providência LA. "A bradicinina melhora o status energético e a actividade da cadeia respiratória mitocondrial num modelo de isquemia miocárdica global". Trabalho apresentado em XXIII Portuguese Congress of Cardiology, 2002.
  123. Duarte AI; Silva S, Moura JP, Monteiro P, Duarte A, Moreno A, Gonçalves L, Providência LA. "O efeito protector mitocondrial do dinitrato de isossorbido durante a isquemia cardíaca não é mediado pelo óxido nítrico". Trabalho apresentado em XXIII Portuguese Congress of Cardiology, 2002.
  124. Duarte AI; Moura JP, Silva S, Monteiro P, Duarte A, Moreno A, Gonçalves L, Providência LA. "Os efeitos protectores mitocondriais da bradicinina são dependentes da produção de óxido nítrico". Trabalho apresentado em XXIII Portuguese Congress of Cardiology, 2002.
  125. Duarte AI; Monteiro P, Duarte A, Gonçalves L, Moreno A, Providência L. "Carvedilol improves mitochondrial energetics in an animal model of global myocardial ischemia". Trabalho apresentado em XIIèmes Journées Europeènes de la Societé Française de Cardiologie, 2002.
  126. Duarte AI; Oliveira CR, Moreira P, Duarte AI, Melo JB, Rego AC, Moreno A, Santos MS. "Aging, oxidative stress and beta-amyloid susceptibility". Trabalho apresentado em 2nd Neurobiology of Aging Conference, 2001.
  127. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Can insulin have a neuroprotective effect in diabetic rat brain synaptosomes under oxidative stress conditions?". Trabalho apresentado em 7ª. Meeting of the Portuguese Society for Neuroscience, 2001.
  128. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "The effect of diabetes and ageing on the rat brain P2 fraction susceptibility to oxidative stress and on the uptake of GABA and glutamate". Trabalho apresentado em FEBS Advanced Course: "Mitochondria in Cell Life and Death", 2001.
  129. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Insulin affects GABA and glutamate accumulation under oxidative stress conditions in rat brain synaptosomes". Trabalho apresentado em 27th FEBS Meeting, 2001.
  130. Duarte AI; Monteiro P, Duarte A, Gonçalves L, Moreno A, Providência L. "Positive impact of carvedilol on the mitochondrial energetics in an animal model of global myocardial ischemia". Trabalho apresentado em 27th FEBS Meeting, 2001.
  131. Duarte AI; Duarte A, Santos MS, Seiça R, Oliveira CR. "Efeito da diabetes e do dano oxidativo no transporte de GABA e glutamato em sinaptossomas isolados de córtex cerebral de rato". Trabalho apresentado em II Congresso de Investigação em Medicina, 2000.
    10.17648/sinaferm-2015-33766
  132. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Oxidative stress affects the transport of GABA and glutamate in diabetic Goto-Kakizaki rat brain synaptosomes: the role of insulin". Trabalho apresentado em 30th Annual Meeting of the Society for Neuroscience, 2000.
  133. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Diabetes and ageing affect the susceptibility to oxidative stress and ATPase activity of rat brain synaptosomes". Trabalho apresentado em XI Portuguese Congress of Biochemistry, 2000.
  134. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Uptake of GABA and glutamate in diabetic Goto-Kakizaki rat brain synaptosomes under oxidative stress conditions: the role of vitamin E (alpha-tocopherol).". Trabalho apresentado em IV Congress on Free Radicals in Chemistry, Biology and Medicine, 1999.
  135. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Effect of oxidative stress in the uptake of GABA and glutamate in diabetic GK rat brain synaptosomes". Trabalho apresentado em VI Meeting of the Portuguese Society for Neuroscience, 1999.
  136. Duarte AI; Duarte AI, Moreira PI, Santos MS, Oliveira CR. "Vinpocetine protects synaptosomes from oxidative stress". Trabalho apresentado em V Reunião Meeting of the Portuguese Society for Neuroscience, 1998.
  137. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Diabetes decreases the susceptibility of synaptosomes to oxidative stress and modifies ATPase activities in GK rats". Trabalho apresentado em XI Portuguese Congress of Biochemistry, 1998.
  138. Duarte AI; Santos MS, Duarte AI, Moreira PI, Oliveira CR. "Synaptosomal response to oxidative stress:effect of vinpocetine". Trabalho apresentado em IX Biennial Meeting International Society for Free Radical Research, 1998.
  139. Duarte AI; Moreira PI, Duarte AI, Santos MS, Oliveira CR. "Under oxidative stress glutamate reverts the aluminium-induced metabolic changes in synaptosomes". Trabalho apresentado em IV Meeting of the Portuguese Society for Neuroscience, 1997.
Recurso online
  1. Duarte AI. Selfie Science @ CNC, by Ana I. Duarte. 2019. https://youtu.be/U5NvrmttowU ; #CNCResearch #CNCVideos #BAW2019 #Neurosciences#BrainAwarenessWeek.
  2. Duarte AI. Duarte AI (2016). Invited comment on “Is sporadic Alzheimer’s disease a form of diabetes?”, posted by P.I. Moreira in J Alzh Dis , Editor’s Blog. 2016.
Resumo em conferência
  1. Duarte AI; Mena D*, Alves IN*, Silva DF, Candeias E, Oliveira CR, Seiça R, Monteiro PF, Moreira PI, Duarte AI. Autor correspondente: Duarte AI. "The neuroprotection by GLP-1 receptor agonists in high cardiovascular risk and neurodegenerative diseases". Trabalho apresentado em Eur J Clin Invest, 2021.
    Publicado
  2. Duarte AI; Duarte AI*, Coelho AR*, Mena D, Silva DF, Marques R, Cagide F, Benfeito S, Soares P, Borges F, Oliveira PJ. "Effect of novel mitochondria-targeted antioxidants in human skin fibroblasts". Trabalho apresentado em Eur J Clin Invest, 2021.
    Publicado
  3. Duarte AI. Autor correspondente: Duarte AI. "Experimental Design and Statistical Principles". Trabalho apresentado em Eur J Clin Invest, 2021.
    Publicado
  4. Duarte AI; Silva DF, Alves IN, Mena D, Vaz DE, Monteiro PF, Moreira PI, Duarte AI. "The neuroprotective effects of peripheral treatment with Evolocumab in middle-aged rat at high cardiovascular risk". Trabalho apresentado em Eur J Clin Invest 50 (Suppl 1): 54ASM-0417, 2020.
    n/a
  5. Duarte AI; Alves IN, Mena D, Silva DF, Seiça R, Oliveira CR, Duarte AI, Moreira PI. "Type 2 diabetes mitigates brain cortical energy metabolism in middle-aged female rats". Trabalho apresentado em Eur J Clin Invest 50 (Suppl 1): 54ASM-0305, 2020.
    Publicado • n/a
  6. Duarte AI; Mena D, Alves IN, Sjögren M, Silva DF, Oliveira CR, Moreira PI, Björkqvist M, Duarte AI. "Co-administration of liraglutide and ghrelin ameliorates brain mitochondrial energy metabolism in the R6/2 mouse model for Huntington’s disease". Trabalho apresentado em Eur J Clin Invest 50 (Suppl 1): 54ASM-0304, 2020.
    Publicado • n/a
  7. Duarte AI; Mena D*, Alves IN*, Silva DF, Vaz DE, Oliveira CR, Candeias E, Oliveira CR, Monteiro PF, Moreira PI, Duarte AI. "Diet-induced high cardiovascular risk compromises brain hippocampal metabolism and long-term spatial memory in middle-aged male rats". Trabalho apresentado em Eur J Clin Invest 50 (Suppl 1): 54ASM-0337, 2020.
    n/a
  8. Duarte AI; Alves IN, Mena D, Seiça R, Oliveira CR, Moreira PI, Duarte AI. "Type 2 diabetes attenuates brain glycolytic and oxidative glucose metabolism in middle-aged female rats". Trabalho apresentado em Eur J Clin Invest 49 (Suppl 1): S8-O6, 2019.
    Publicado
  9. Duarte AI; Mena D, Alves IN, Sjögren M, Oliveira CR, Moreira PI, Björkqvist M, Duarte AI. "Dual administration of liraglutide and ghrelin recovers brain mitochondrial energy metabolism in the R6/2 mouse for Huntington’s disease". Trabalho apresentado em Eur J Clin Invest 49 (Suppl 1): P029-T, 2019.
  10. Duarte AI; Duarte AI, Alves IN, Mena D, Candeias E, Oliveira CR, Monteiro PF, Moreira PI. "Diet-induced high cardiovascular risk impairs brain hippocampal metabolism and long-term spatial memory in middle-aged male rats". Trabalho apresentado em Eur J Clin Invest 49 (Suppl 1):P029-F, 2019.
    Publicado
  11. Pinho BR, Duarte AI, Almeida LM, Oliveira A, Canas PM, Moreira PI, Murphy MP, Oliveira JMA. "Profiling of proteostasis, mitochondrial and redox markers in the brain and liver from the R6/2 Huntington’s disease mouse model". Trabalho apresentado em Eur J Clin Invest 49 (Suppl 1): P020-F, 2019.
    Publicado
  12. Duarte AI. "IUGR Remodels Fetal Cardiac Left Ventricular (LV) Mitochondria in Baboons". Trabalho apresentado em Reproductive Sciences 26: 240, 2019.
    Publicado
  13. Duarte AI. "Effects of dual administration of liraglutide and ghrelin on brain mitochondrial metabolism in the R6/2 mouse". Trabalho apresentado em J Neurol Neurosurg Psychiatry 89: Suppl 1 A92., 2018.
    10.1158/1557-3125.myc15-ia08
  14. Duarte AI. "Effects of MitoQ on behavioural and biochemical phenotypes of a Huntington’s disease mouse model". Trabalho apresentado em J Neurol Neurosurg Psychiatry 89: Suppl 1 A91-92, 2018.
    Publicado
  15. Duarte AI. "Diabetes e doença cardíaca: uma herança da vida intrauterina?". Trabalho apresentado em Revista Portuguesa de Diabetes. Vol. 13: 1, p. 22, 2018.
    Publicado
  16. Duarte AI. "Remodeling of cardiac mitochondrial profile in the fetal baboon by moderate global maternal nutrient reduction". Trabalho apresentado em Eur J Clin Invest 47 (Suppl 1): O2.27, 2017.
    Publicado
  17. Duarte AI. "Effects of peripheral (co-)administration of liraglutide and ghrelin in the R6/2 mouse brain function". Trabalho apresentado em J Neurol Neurosurg Psychiatry 87: Suppl 1 A98, 2016.
    Publicado
  18. Duarte AI. "The effect of ghrelin administration in the R6/2 mouse model of Huntington’s disease". Trabalho apresentado em J Neurol Neurosurg Psychiatry 87: Suppl 1 A98.2, 2016.
    Publicado
  19. Pereira SP, Tavares LC, Duarte AI, Santos MS, Baldeiras I, Moreno AJ, Cox LA, Li C, Nathanielsz PW, Nijland MJ Oliveira. "Maternal nutrition reduction causes cardiac mitochondrial remodeling in 0.65G fetal baboons". Trabalho apresentado em Eur J Clin Invest 46: 58, 2016.
    Publicado • 10.1136/annrheumdis-2017-eular.5214
  20. Duarte AI. "Maternal nutrition and fetal mitochondrial fitness". Trabalho apresentado em Eur J Clin Invest 46: 46, 2016.
    Publicado
  21. Duarte AI; Cavaco JE, Rato L, Alves MG, Duarte AI, Santos MS, Moreira PI, Oliveira PF. "How does Sertoli cell metabolism responds to the reduced testosterone levels induced by progressive stages of diabetes mellitus?". Trabalho apresentado em Medicine. doi: 10.1097/MD.0000000000002371, 2016.
    Publicado
  22. Duarte AI; Duarte AI, Almeida C, Candeias E, Sebastião I, Seiça R, Santos MS, Oliveira CR, Moreira PI. "The role of gender on brain metabolism in middle-aged type 2 diabetic rats". Trabalho apresentado em Sinapse 15: 235, 2015.
    Publicado
  23. Duarte AI; Candeias E, Sebastião I, Machado N, Santos MS, Oliveira CR, Duarte AI, Moreira PI. "The anti-diabetic drug liraglutide rescues Alzheimer disease pathology in mature mice". Trabalho apresentado em Sinapse 15: 225, 2015.
    Publicado
  24. Duarte AI; Sebastião I, Candeias E, Santos MS, Oliveira CR, Moreira PI, Duarte AI. "Can peripheral administration of the anti-type 2 diabetic exendin-4: protect against brain dysfunction and apoptosis?". Trabalho apresentado em Sinapse 15: 223, 2015.
    Publicado
  25. Duarte AI; Rato L, Alves MG, Duarte AI, Santos MS, Moreira PI, Cavaco JE, Oliveira PF. "Progressive stages of diabetes mellitus induce testosterone deficiency promoting a modulation of Sertoli cell metabolism". Trabalho apresentado em Human Reproduction. Great Clarendon St, Oxford OX2 6DP, England: Oxford Univ Press, 2015.
    Publicado
  26. Duarte AI. "Pre-diabetes disrupts testicular PGC1-a/SIRT3 axis prompting to oxidative stress". Trabalho apresentado em Biochim Biophys Acta 1837: Supplement e64, 2014.
    Publicado • 10.1158/1538-7445.nonrna15-a01
  27. Duarte AI. "Alzheimer disease hallmarks in adult type 2 diabetic female rat brain: Is oxidative stress the predecessor?". Trabalho apresentado em FEBS J. 280 (Issue suppl. S1): 419, 2013.
    Publicado
  28. Duarte AI; Rato L, Duarte AI, Alves MG, Santos MS, Moreira PI, Socorro S, Cavaco JE, Oliveira PF. "Testicular mitochondrial bioenergetics is altered in pre-diabetes induced by a high-energy diet in rats". Trabalho apresentado em FEBS J. 280 (Issue suppl. S1): 256, 2013.
    Publicado
  29. Duarte AI; Duarte AI, Candeias E, Correia S, Carvalho C, Fernandes MA, Seiça R, Santos MS, Oliveira CR, Moreira PI. "Type 2 diabetic female rats are less vulnerable to Alzheimer disease than males: the role of brain insulin/IGF-1 and estrogen". Trabalho apresentado em Eur J Clin Invest. 43 (Special issue: SI, suppl. 1): 75, 2013.
    Publicado
  30. Duarte AI. "Gender effects in adult rat brains: type 2 diabetes and Alzheimer disease hallmarks". Trabalho apresentado em Eur J Clin Invest. 43 (Special issue: SI, suppl. 1): 75-76, 2013.
    Publicado • 10.1055/s-0039-1688357
  31. Duarte AI. "Type 2 diabetic female rats are less vulnerable to Alzheimer’s disease than males: the role of brain insulin/IGF-1 and estrogen.". Trabalho apresentado em Neurodegenerative Diseases 11 (S1): 1854, 2013.
    Publicado
  32. Duarte AI; Cunha-Oliveira T, Naia L, Ferreira IL, Rosenstock T, Duarte AI, Ribeiro M, Laço MN, Ribeiro M, Oliveira CR, Saudou F. "Activation of IGF-1 and insulin signaling pathways ameliorate energy metabolism and mitochondrial function in Huntington’s disease human lymphoblasts". Trabalho apresentado em Program Nº. 154.05/G19. 2012 Neuroscience Meeting Planner. New Orleans, LA: Society for Neuroscience, 2012. Online., 2012.
    Publicado
  33. Duarte AI; Lopes C, Duarte AI, Hayden M, Rego AC. "Peripheral and cerebral metabolic features in an animal model of Huntington's disease". Trabalho apresentado em 2012 IEEE 2nd Portuguese Meeting in Bioengineering, ENBENG 2012. doi: 10.1109/enbeng.2012.6331390, 2012.
    Publicado
  34. Duarte AI; González-Burgos E, Duarte AI, Carretero ME, Moreira PI, Gómez-Serranillos MP. "Linearol as natural mitochondria-targeted antioxidant: potential benefits in neurodegenerative diseases". Trabalho apresentado em Free Rad Biol Med. Suppl, 2012.
    Publicado
  35. Duarte AI. "Insulin-like growth factor-1 protects against diabetic features in the R6/2 mouse model of Huntington’s disease". Trabalho apresentado em Program No. 859.8/L11. 2010 Neuroscience Meeting Planner. San Diego, CA: Society for Neuroscience, 2010. Online., 2010.
    Publicado • 10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4368
  36. Duarte AI; Duarte AI, Petit G, Ranganathan S, Li J-Y, Björkqvist M, Oliveira CR, Brundin P, Rego AC. "Effect of IGF-1 on diabetic parameters in an in vivo model of Huntington’s disease". Trabalho apresentado em Clinical Genet 76 (Suppl 1): 29. doi: 10.1111/j.1399-0004.2009.01229.x., 2009.
    Publicado
  37. Duarte AI; Duarte AI, Ribeiro M, Rego AC, Oliveira CR. "Effect of insulin on oxidative stress and caspase-3 activity in a cellular model of Huntington's disease". Trabalho apresentado em Frontiers in Neuroscience. Conference Abstract: 11th Meeting of the Portuguese Society for Neuroscience. doi: 10.3389/conf.neuro.01.2009.11.070., 2009.
    Publicado
  38. Duarte AI; Duarte AI, Ribeiro M, Ferreira IL, Oliveira CR, Rego AC. "Insulin protects from oxidative stress and caspase-3 activation in an in vitro model of Huntington’s disease". Trabalho apresentado em J Neurol Neurosurg Psych 79 (Suppl 1):A22. http://jnnp.bmj.com/content/79/Suppl_1.toc, 2008.
    Publicado
  39. Duarte AI; Ribeiro M, Ferreira IL, Duarte AI, Oliveira CR, Rego AC. "Detailed oxidative stress features in an in vitro model of Huntington’s disease". Trabalho apresentado em J Neurol Neurosurg Psych 79 (Suppl 1):A24. http://jnnp.bmj.com/content/79/Suppl_1.toc, 2008.
    Publicado
  40. Duarte AI; Duarte AI, Proença T, Monteiro P, Gonçalves LM, Providência LA, Seiça R, Oliveira CR, Santos MS, Rego AC. "Oxidative stress in type 2 diabetic GK rat retina during aging.". Trabalho apresentado em Free Radic Res 41 (Suppl 1): S24. doi: 10.1080/10715760701615118, 2007.
    Publicado
  41. Duarte AI; Duarte AI, Santos MS, Santos P, Oliveira CR, Rego AC. "Insulin neuroprotection against oxidative stress involves Akt/GSK-3ß signalling pathways and changes in protein expression". Trabalho apresentado em Free Radic Res 41 (Suppl 1): S24. doi: 10.1080/10715760701615118., 2007.
    Publicado
  42. Duarte AI; Duarte A, Santos MS, Oliveira CR, Rego AC. "Neuroprotective role of insulin against oxidative stress is mediated by Akt and GSK-3ß signaling pathways". Trabalho apresentado em Program No. 185.5. 2006 Neuroscience Meeting Planner. Atlant, GA: Society for Neuroscience, 2006. Online., 2006.
    Publicado
  43. Duarte AI; Duarte A, Proença T, Santos MS, Seiça R, Oliveira CR, Rego AC. "Retinal degeneration during aging in type-2 diabetic Goto-Kakizaki rats". Trabalho apresentado em Program No. 977.4. 2005 Abstract Viewer/Itinerary Planner. Washington, DC. Society for Neuroscience, 2005. Online., 2005.
    Publicado
  44. Duarte AI; Duarte A, Proença T, Santos MS, Seiça R, Oliveira CR, Rego AC. "Retinal degeneration upon aging and type 2 diabetes". Trabalho apresentado em Sinapse 5:116, 2005.
    Publicado
  45. Duarte AI. "Carvedilol protects ischemic cardiac mitochondria from oxidative stress-induced injuries". Trabalho apresentado em J Mol Cell Cardiol. 37: 191. https://www.journals.elsevier.com/journal-of-molecular-and-cellular-cardiology/, 2004.
    Publicado
  46. Duarte AI; Monteiro P, Carreira R, Duarte A, Santos MS, Rego AC, Oliveira CR, Goncalves L, Providencia LA. "Carvedilol protects cardiac mitochondria submitted to ischemia-reperfusion from oxidative stress-induced injuries". Trabalho apresentado em J Mol Cell Cardiol. 37:191. https://www.journals.elsevier.com/journal-of-molecular-and-cellular-cardiology/, 2004.
    Publicado
  47. Duarte AI; Duarte A, Proença T, Santos MS, Oliveira CR, Rego AC. "Insulin protects against oxidative stress-induced metabolic dysfunction in cultured cortical neurons". Trabalho apresentado em FENS Abstr. 2004; 2:230.5, 2004.
    Publicado
  48. Duarte AI; Monteiro P, Carreira R, Duarte A, Santos MS, Rego C, Oliveira C, Goncalves L, Providencia LA. "Valsartan improves mitochondrial phosphorylation in acute myocardial ischemia". Trabalho apresentado em Arteriosc Thromb Vasc Biol. 24:P220, 2004.
    Publicado
  49. Duarte AI; Carreira R, Duarte A, Monteiro P, Santos MS, Rego AC, Oliveira CR, Gonçalves L, Providência LA. "O carvedilol protege mitocôndrias cardíacas isquémicas de lesões induzidas pelo stress oxidativo". Trabalho apresentado em Rev Port Cardiol. 2004; 23 (Supl I):I-36, 2004.
    Publicado
  50. Duarte AI; Duarte AI, Santos MS, Oliveira CR, Rego AC. "Insulin neuroprotection against oxidative stress in cultured cortical neurons – Involvement of glutathione antioxidant defense". Trabalho apresentado em Program No. 638.15. 2003 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience. Online., 2003.
    Publicado
  51. Duarte AI; Monteiro P, Duarte A, Goncalves L, Providencia LA. "Valsartan improves mitochondrial phosphorylation in acute myocardial ischaemia.". Trabalho apresentado em Eur Heart J. 24:526, 2003.
    Publicado
  52. Duarte AI; Monteiro P, Silva S, Moura JP, Duarte A, Moreno A, Goncalves L, Providencia LA. "The protective effect of isosorbide dinitrate on cardiac mitochondria during ischaemia is not mediated by nitric oxide". Trabalho apresentado em Eur Heart J. 23:218, 2003.
    Publicado
  53. Duarte AI; Monteiro P, Duarte A, Goncalves L, Providencia LA. "Nitric oxide mediates bradykinin cardioprotective effects". Trabalho apresentado em Eur Heart J 2003, 2003.
    Publicado
  54. Duarte AI; Monteiro P, Duarte A, Oliveira PJ, Gonçalves L, Providência LA. "Bradykinin protective effects on cardiac mitochondria are nitric oxide-dependent". Trabalho apresentado em Eur J Heart Failure 2003, 2003.
    Publicado
  55. Duarte AI; Monteiro P, Duarte A, Oliveira PJ, Gonçalves L, Providência LA. "O valsartan reduz a actividade do complexo I mitocondrial durante a isquemia miocárdica aguda". Trabalho apresentado em Rev Port Cardiol. 2003; 22 (Supl.III):51, 2003.
    Publicado
  56. Duarte AI. "O valsartan melhora a rapidez da fosforilação durante a isquemia miocárdica global". Trabalho apresentado em Rev Port Cardiol. 2003; 22 (Supl. III):51, 2003.
    Publicado
  57. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Insulin affects synaptosomal GABA and glutamate transport under oxidative stress conditions in diabetic rat brain". Trabalho apresentado em Program No. 431.11. 2002 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience. CD-ROM., 2002.
    Publicado
  58. Duarte AI; Monteiro P, Moura JP, Silva S, Duarte A, Oliveira PJ, Moreno A, Gonçalves L, Providência LA. "Effects of bradykinin on mitochondrial respiratory chain function in an animal model of global myocardial ischemia". Trabalho apresentado em Biochem Biophys Acta (EBEC short reports). 2002; 12:296, 2002.
    Publicado
  59. Duarte AI; Moura JP, Monteiro P, Silva S, Duarte A, Oliveira PJ, Moreno A, Gonçalves L, Providência LA. "Bradykinin protective effects on cardiac mitochondria are nitric oxide-dependent.". Trabalho apresentado em Biochem Biophys Acta (EBEC short reports). 2002; 12:297, 2002.
    Publicado
  60. Duarte AI; Silva S, Monteiro P, Moura JP, Duarte A, Oliveira PJ, Moreno A, Gonçalves L, Providência LA. "The protective effect of isosorbide dinitrate on cardiac mitochondria during ischemia is not mediated by nitric oxide". Trabalho apresentado em Biochem Biophys Acta (EBEC short reports). 2002; 12:311, 2002.
    Publicado
  61. Duarte AI; Monteiro P, Duarte A, Moreno A, Gonçalves L, Providência LA. "Positive impact of bradikinin on mitochondrial metabolism during acute ischemia – an explanation for its preconditioning effects?". Trabalho apresentado em J Am Coll Cardiol.; 39 (Supl B):247B, 2002.
    Publicado
  62. Duarte AI; Monteiro P, Duarte A, Moreno A, Gonçalves L, Providência LA. "Impact of pyruvate on the mitochondrial function and energetics in an animal model of ex-vivo global myocardial ischemia.". Trabalho apresentado em J Am Coll Cardiol.; 39 (Supl B):103B, 2002.
    Publicado
  63. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Oxidative stress and glutamate accumulation in diabetic GK rat brain synaptosomes: the role of vitamin E (a-tocopherol)". Trabalho apresentado em Free Rad Biol Med.; 33 (supl 1):315,508, 2002.
    Publicado
  64. Duarte AI; Monteiro P, Silva S, Moura JP, Duarte A, Moreno A, Goncalves L, Providencia LA. "The protective effect of isosorbide dinitrate on cardiac mitochondria during ischemia is not mediated by nitric oxide". Trabalho apresentado em Eur Heart J.; 23 (Supl):218, 2002.
    Publicado
  65. Duarte AI; Monteiro P, Duarte A, Moreno A, Gonçalves L, Providência LA. "Bradykinin improves the energetic status and the respiratory chain´s activity in an ex-vivo model of global myocardial ischemia". Trabalho apresentado em Eur J Heart Failure.; 1 (Supl 1):78, 2002.
    Publicado
  66. Duarte AI; Monteiro P, Duarte A, Moreno A, Gonçalves L, Providência LA. "O piruvato melhora a energética mitocondrial num modelo animal ex-vivo de isquemia miocárdica global.". Trabalho apresentado em Rev Port Cardiol.; 21 (Supl I):I-45, 2002.
    Publicado
  67. Duarte AI; Monteiro P, Duarte A, Moreno A, Gonçalves L, Providência LA. "A bradicinina melhora o status energético e a actividade da cadeia respiratória mitocondrial num modelo de isquemia miocárdica global". Trabalho apresentado em Rev Port Cardiol. 2002; 21 (Supl I):I-81, 2002.
    Publicado
  68. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Poderá a insulina exercer um efeito neuroprotector em condições de stresse oxidativo?". Trabalho apresentado em Arquivos de Medicina; 16 (Supl 2):25, 2002.
    Publicado
  69. Duarte AI; Monteiro P, Duarte A, Gonçalves L, Moreno A, Providência L. "Carvedilol improves mitochondrial energetics in an animal model of global myocardial ischemia". Trabalho apresentado em Archives des Maladies du Coeur et des Vaisseaux; 95 (supl 3):136, 2001.
    Publicado
  70. Duarte AI; Duarte A, Santos MS, Seiça R, Oliveira CR. "Insulin affects GABA and glutamate accumulation under oxidative stress conditions in rat brain synaptosomes". Trabalho apresentado em Eur J Biochem.; 268 (supl 1):148, 2001.
    Publicado
  71. Duarte AI. "Positive impact of carvedilol on the mitochondrial energetics in an animal model of global myocardial ischemia". Trabalho apresentado em Eur J Biochem.; 268 (supl 1):259, 2001.
    Publicado
  72. Duarte AI; Monteiro P, Duarte A, Gonçalves L, Moreno A, Providência L. "O carvedilol melhora a energética mitocondrial num modelo animal de isquemia miocárdica global". Trabalho apresentado em Rev Port Cardiol. 2001; 20 (supl. IV):52, 2001.
    Publicado
  73. Duarte AI; Duarte AI, Santos MS, Seiça R, Oliveira CR. "Oxidative stress affects the transport of GABA and glutamate in diabetic Goto-Kakizaki rat brain synaptosomes: the role of insulin". Trabalho apresentado em Society for Neuroscience Abstracts. 2000; 26:818.2, 2000.
    Publicado
Tese / Dissertação
  1. Duarte AI. "Influence of oxidative stress and type 2 diabetes mellitus on neuronal function and metabolism – The neuroprotective role of insulin". Doutoramento, Universidade de Coimbra Departamento de Ciências da Vida, 2007.
  2. Duarte AI. "ATPases membranares, transporte de neurotransmissores e stresse oxidativo: influência da diabetes e envelhecimento". Mestrado, Universidade de Coimbra Departamento de Ciências da Vida, 2002.
Website
  1. Duarte AI. Blog "Ciência a brincar". 2006. http://cienciaabrincar.blogspot.com/.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2021/03/09 The neuroprotective effects of insulin/IGF-1/GLP-1 signaling recovery in type 2 diabetes and neurodegenerative diseases Pre-Conference Symposium ‘PROTECTIVE EFFECTS OF INSULIN AND INCRETINS IN AD/PD’
15th International Conference on Alzheimer’s and Parkinson’s Diseases (AD/PD2021)
2021/01/20 Data and Statistical Analysis - Basic concepts and applications Workshop Fundamentals of Cellular and Molecular Metabolism: Relevance for Health and Disease
CNC- Center for Neuroscience and Cell Biology, University of Coimbra (Coimbra, Portugal) and ITMO University (St. Petersburg, Russia)
2020/10/15 We are what we eat? Dietary habits and neurodegenerative diseases ALIMENTAÇÃO SAUDAVEL – IMPORTANTE EM TEMPOS DE PANDEMIA. IMPACT OF NUTRITION ON HEALTH - IMPORTANT IN PANDEMIC TIMES
CNC- Center for Neuroscience and Cell Biology, University of Coimbra and Faculty of Medicine, University of Porto
2020/09 The neuroprotective effects of peripheral treatment with Evolocumab in middle-aged rat at high cardiovascular risk. (Accepted for a flash talk plus poster) European Society for Clinical Investigation Virtual Meeting 2020 – COVID19 Edition. September 20th-30th 2020
European Society for Clinical Investigation
2020/09 Type 2 diabetes mitigates brain cortical energy metabolism in middle-aged female rats. (Accepted for a flash talk plus poster) European Society for Clinical Investigation Virtual Meeting 2020 – COVID19 Edition
European Society for Clinical Investigation
2020/09 Co-administration of liraglutide and ghrelin ameliorates brain mitochondrial energy metabolism in the R6/2 mouse model for Huntington’s disease. (Accepted for a short talk plus poster) European Society for Clinical Investigation Virtual Meeting 2020 – COVID19 Edition
European Society for Clinical Investigation
2020/09 Diet-induced high cardiovascular risk compromises brain hippocampal metabolism and long-term spatial memory in middle-aged male rats. (Accepted for a flash talk plus poster) European Society for Clinical Investigation Virtual Meeting 2020 – COVID19 Edition.
European Society for Clinical Investigation
2020/02/05 The interplay between redox signalling and proteostasis in Huntington’s disease: in vivo effects of mitoQ in R6/2 mice SPF 2020 - Reunião Anual da Sociedade Portuguesa de Farmacologia
(Coimbra, Portugal)
2019/10/11 Type 2 diabetes attenuates brain cortical energy metabolism in female rats at midlife 33ª. Reunião do Grupo de Estudos Envelhecimento Cerebral e Demência (GEECD)
(Curia, Portugal)
2019/10/11 Dual administration of liraglutide and ghrelin ameliorates brain mitochondrial energy metabolism in Huntington’s disease R6/2 mice 33ª. Reunião do Grupo de Estudos Envelhecimento Cerebral e Demência (GEECD)
(Curia, Portugal)
2019/05/23 Type 2 diabetes attenuates brain glycolytic and oxidative glucose metabolism in middle-aged female rats ESCI2019 - 53rd Annual Scientific Meeting of the European Society for Clinical Investigation
(Coimbra, Portugal)
2019/02/06 In vivo effects of the mitochondria-targeted antioxidant MitoQ in a mouse model of Huntington’s disease SPF 2019 - Reunião Anual da Sociedade Portuguesa de Farmacologia
(Porto, Portugal)
2019 From type 2 diabetes to Alzheimer’s disease: the Mynotaur labyrinth or “just” a challenging puzzle? 1st Retreat of the Center for Neuroscience & Cell Biology Neuroscience Area
(Miranda do Corvo, Portugal)
2019 Doença de Alzheimer: os nossos “sonhos” e a realidade actual NISOB - Universidade Sénior de Oliveira do Bairro
(Oliveira do Bairro, Portugal)
2018/05/30 Diabetes tipo 2 e doença de Alzheimer: apenas uma questão de idade? Sarau Académico da Universidade de Aveiro
Universidade de Aveiro (Aveiro, Portugal)
2018/03/09 Diabetes e doença cardíaca: uma herança da vida intrauterina? 14º Congresso Português de Diabetes
(Algarve, Portugal)
2017/12/15 Restoring insulin action & glucose metabolism in Alzheimer’s disease: Our short-term perspectives. Prospective Focus Discussion on Alzheimer’s Outlook 2017: Drug targets in Alzheimer’s disease and dementia – Current and emerging avenues
Fondation Médéric Alzheimer (Paris, França)
2017/06/09 Type 2 diabetes and Alzheimer disease: Sex, Drugs and… ? Seminars at Center for Neuroscience and Cell Biology 2017 – Summer Series
CNC - Center for Neuroscience and Cell Biology (Coimbra, Portugal)
2017/05/17 Remodeling of cardiac mitochondrial profile in the fetal baboon by moderate global maternal nutrient reduction 51st European Society for Clinical Investigation (ESCI) Conference 2017
(Genoa, Itália)
2016/12/19 Type 2 diabetes & Alzheimer disease: Let's talk about sex? 1st Meeting on Biomedical Research @ UC
University of Coimbra (Coimbra, Portugal)
2016/12/08 Chronic high fat diet consumption along with aging impairs the striatal pathway – Linagliptin neuroprotective effects XIX National Congress on Biochemistry (SPB2016)
(Guimarães, Portugal)
2016/06/03 Envelhecimento cerebral saudável em Neurociências: os nossos “sonhos” e a realidade actual Brain Awareness Week 2016
CNC - Center for Neuroscience and Cell Biology (Coimbra, Portugal)
2016/04/28 Maternal nutrition and fetal mitochondrial fitness 50th Annual Scientific Meeting of the European Society for Clinical Investigation
(Paris, França)
2016/04/27 Maternal nutrition reduction causes cardiac mitochondrial remodeling in 0.65G fetal baboons 50th Annual Scientific Meeting of the European Society for Clinical Investigation
(Paris, França)
2015/05/29 The role of gender on brain metabolism in middle-aged type 2 diabetic rats 29ª. Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência
(Aveiro, Portugal)
2015/05/29 The anti-diabetic drug liraglutide rescues Alzheimer disease pathology in mature mice 29ª. Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência.
(Aveiro, Portugal)
2015/05/29 Can peripheral administration of the anti-type 2 diabetic exendin-4: protect against brain dysfunction and apoptosis? 29ª. Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência
(Aveiro, Portugal)
2014/12/15 Brain dysfunction upon chronic type 2 diabetes: the (neuro)protective effects of peripheral exendin-4 therapy XII CNC Annual Meeting
CNC - Center for Neuroscience and Cell Biology (Coimbra, Portugal)
2014/06/27 Brain dysfunction and cell death in type 2 diabetes: Is the peripheral treatment with the anti-type 2 diabetic exendin-4 advantageous? 28ª. Reunião do Grupo de Estudos em Envelhecimento Cerebral e Demência
(Aveiro, Portugal)
2014/06/27 Exendin-4 therapy in type 2 diabetic Goto-Kakizaki rats: impact in cognition, metabolism and dementia hallmarks 28ª. Reunião do Grupo de Estudos em Envelhecimento Cerebral e Demência
(Aveiro, Portugal)
2014/06/27 Gender and type 2 diabetes affect brain cortical intracellular signaling pathways, oxidative stress vulnerability and development of AD-related hallmarks 28ª. Reunião do Grupo de Estudos em Envelhecimento Cerebral e Demência
(Aveiro, Portugal)
2014/06/13 The crosstalk between reproductive senescence and Alzheimer disease-like hallmarks in type 2 diabetic brain: a role for peripheral exendin-4 therapy? Seminars at Center for Neuroscience and Cell Biology 2014 – Summer Series
CNC - Center for Neuroscience and Cell Biology (Coimbra, Portugal)
2014/03/11 Aprendizagem e memória: o papel do sono e do exercício físico Brain Awareness Week 2014
CNC - Center for Neuroscience and Cell Biology (Coimbra, Portugal)
2013/05/30 Insulin/IGF-1/estrogen signalling protects against lipid oxidation and neurodegenerative events in type 2 diabetic female rat brain XIII Meeting of the Portuguese Neuroscience Society
(Luso, Portugal)
2013/05/30 IGF-1 intranasal administration rescues Huntington's disease phenotypes in YAC128 mice XIII Meeting of the Portuguese Neuroscience Society
(Luso, Portugal)
2013/05/30 Adult female rat brain is less prone to Alzheimer disease hallmarks than male brain: the role of insulin/IGF-1 signaling XIII Meeting of the Portuguese Neuroscience Society
(Luso, Portugal)
2013/04/17 Type 2 diabetic female rats are less vulnerable to Alzheimer disease than males: the role of brain insulin/IGF-1 and estrogen 47th Annual Scientific Meeting of the European Society for Clinical Investigation 2013
(Albufeira, Portugal)
2013/03/15 Aprendizagem, memória e sono Brain Awareness Week 2013
(Lousã, Portugal)
2012/05/24 Envelhecimento cerebral saudável na perspectiva das Neurociências: os nossos “sonhos” e a realidade actual IV Ciclo de Conferências em Envelhecimento Activo
(Miranda do Corvo, Portugal)
2012/03/22 Juventude (cerebral) eterna: realidade ou utopia? Brain Awareness Week 2012
(Miranda do Corvo, Portugal)
2011/07 The role of sex steroids on Sertoli cell metabolism VI Annual Meeting of the Centro de Investigação em Ciências da Saúde
(Covilhã, Portugal)
2011/03/18 Longevidade, Envelhecimento e Senescência Cerebral: Existirá o elixir da juventude (cerebral) eterna? Brain Awareness Week 2011
CNC - Center for Neuroscience and Cell Biology (Coimbra, Portugal)
2010/11/15 Oxidative stress in aging PhD Program in Biology and Biomedicine, Advanced Course on Biology of Aging
CNC - Center for Neuroscience and Cell Biology (Coimbra, Portugal)
2010/11/04 Protection by IGF-1 against diabetic features in Huntington’s disease R6/2 mice model 4ª Reunião Anual da Rede Portuguesa da European Huntington’s Disease Network 2010
(Espinho, Portugal)
2010/06/25 Role of insulin and IGF-1 in metabolism in Huntington’s disease: studies in cortical neurons from YAC128 transgenic mice and human lymphoblasts 24ª. Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência
(Tomar, Portugal)
2010/06/25 Peripheral and cerebral diabetic features in an animal model of Huntington’s disease expressing full-length mutant huntingtin 24ª. Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência
(Tomar, Portugal)
2010/05/06 Protection by IGF-1 against diabetic features in Huntington’s disease R6/2 mice model ENI-Net Final Meeting
(Coimbra, Portugal)
2010/05/03 Diabetes and neuronal metabolism in Huntington’s disease Seminars on Neuropharmacology & Functional Imaging 2010
Faculty of Pharmacy, University of Porto (Porto, Portugal)
2010/03/16 O Cérebro: Aquela Máquina Brain Awareness Week 2010
Colégio de Quiaios (Quiaios, Figueira da Foz, Portugal)
2009/06/26 Efeito do IGF-1 em parâmetros diabéticos num modelo in vivo da doença de Huntington 23a. Reunião do Grupo de Estudos em Envelhecimento Cerebral e Demência
(Luso, Portugal)
2008/07/04 Neuroprotecção pela insulina: Como se constrói o puzzle? Ciência 2008 em Portugal – Encontro com Laboratórios Associados
(Lisboa, Portugal)
2008/04/09 Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes International Courses on Toxicology 2008 - Metabolic Toxicology: From Pathway to Organism
(Coimbra, Portugal)
2008/04/09 Food deprivation enhances oxidative stress in rat brain International Courses on Toxicology 2008 - Metabolic Toxicology: From Pathway to Organism
(Coimbra, Portugal)
2007/11/28 Mitochondria dysfunction and oxidative stress in aging: is insulin neuroprotective? 2007 LINK-AGE Meeting and IBMC Fall Symposium
(Porto, Portugal)
2007/10/10 Insulin neuroprotection against oxidative signalling pathways and changes in protein¿stress involves Akt/GSK-3 expression 2007 European Meeting of the Society for Free Radical Research International
(Vilamoura, Portugal)
2007/05/23 Insulin neuroprotection against oxidative signalling pathways and changes in protein¿stress is mediated by Akt and GSK-3 expression 10ª. Reunião da Sociedade Portuguesa de Neurociências
(Ofir, Portugal)
2006/12/05 Akt/GSK-3¿ signalling pathways mediate insulin neuroprotection against oxidative stress and changes in protein expression XXVII Reunião da Sociedade Portuguesa de Farmacologia
(Porto, Portugal)
2005/06/03 Aging affects retinal degeneration in type 2 diabetic Goto-Kakizaki rats 19ª. Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência
(Tomar, Portugal)
2004/12/02 Insulin protection against oxidative damage in neuronal cells XIV Portuguese Congress of Biochemistry
(Vilamoura, Portugal)
2004/11/17 A insulina protege os neurónios corticais em cultura contra o stresse oxidativo IV Congresso de Investigação em Medicina
(Coimbra, Portugal)
2004/06/04 Insulin prevents the metabolic dysfunction induced by oxidative stress in cultured cortical neurons 18ª Reunião do Grupo de Estudos de Envelhecimento Cerebral e Demência
(Óbidos, Portugal)
2004/03/27 O carvedilol protege mitocôndrias cardíacas isquémicas de lesões induzidas pelo stress oxidativo XXV Portuguese Congress of Cardiology
(Vilamoura, Portugal)
2004/03/20 Poderá a insulina exercer um efeito neuroprotector em condições de stresse oxidativo? 5th Portuguese Congress of Diabetes
(Vilamoura, Portugal)
2003/12/04 Insulin enhances antioxidant defenses upon ascorbate/Fe2+-induced oxidative stress in cultured cortical neurons VI Portuguese Congress on Free Radicals in Chemistry, Biology and Medicine/1st Luso-Spanish Congress on Free Radicals
(Coimbra, Portugal)
2003/06/21 Bradykinin protective effects on cardiac mitochondria are nitric oxide-dependent Heart Failure/ISHR-ES Meeting 2003
(Strasbourg, França)
2003/04/27 O valsartan melhora a rapidez da fosforilação durante a isquemia miocárdica global XXIV Portuguese Congress of Cardiology
(Funchal, Portugal)
2003/04/27 O valsartan reduz a actividade do complexo I mitocondrial durante a isquemia miocárdica aguda XXIV Portuguese Congress of Cardiology
(Funchal, Portugal)
2002/12/05 Bradykinin protective effects on cardiac mitochondria are nitric oxide-dependent XII Portuguese Congress of Biochemistry
(Lisbon, Portugal)
2002/04/13 O piruvato melhora a energética mitocondrial num modelo de isquemia miocárdica global XXIII Portuguese Congress of Cardiology
(Vilamoura, Portugal)
2001/12/18 Can we treat mitochondrial dysfunction in heart failure? 4th Coimbra International Meeting on Cardiovascular Diseases
(Coimbra, Portugal)
2001/12/13 Efeitos da vitamina E na susceptibilidade à peroxidação lipídica e no transporte de glutamato em ratos diabéticos GK em condições de stresse oxidativo V Congress on Free Radicals in Chemistry, Biology and Medicine
(Porto, Portugal)
2001/06/01 Acumulação sinaptossomal de GABA e glutamato em condições de stresse oxidativo: efeito da insulina 15ª. Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência
(Peniche, Portugal)
2000/06/02 Efeito da diabetes e do envelhecimento na susceptibilidade ao dano oxidativo e na actividade de ATPases membranares de sinaptossomas isolados de córtex cerebral de rato 14ª. Reunião do Grupo de Estudos do Envelhecimento Cerebral e Demência
(Luso, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2021/12/01 - Atual n/a
Orientador
PhD in Cellular and Molecular Biology (Doutoramento)
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2021/02 - Atual Laboratorial Project, BSc in Medicinal Chemistry, University of Coimbra
Coorientador
2021/02 - Atual BSc in Biology - Project Report
Orientador
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2020/10/01 - Atual Volunteer MSc Researcher
Orientador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2020/09/01 - Atual Volunteer MSc Researcher
Orientador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2020/02 - Atual BSc in Biochemistry Project Report
Orientador de Filipa Gomes Ferraz
Bsc Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2019/11 - Atual MSc Research Fellow
Orientador de Maria Inês Alves
MSc Research Fellow (Outra)
Universidade de Coimbra Faculdade de Medicina, Portugal
2019/11 - Atual MSc Research Fellow
Orientador de Débora Mena
MSc Research Fellow (Outra)
Universidade de Coimbra Faculdade de Medicina, Portugal
2019/10 - Atual BSc in Biology - Project Report
Orientador de Diane Estanqueiro Vaz
BSc Biology (Licenciatura/Bacharelato)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2019/09/01 - Atual Supervision of international Post-Doctoral Researcher
Orientador de Daniela Franco da Silva
PhD (Doutoramento)
CNC.IBILI, Portugal
2019/04 - Atual BSc Biology - Laboratorial tutoring of an International student
Coorientador de Federica
BSc (Iniciação científica)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2019/02 - Atual BSc Biomedical Engineering - Laboratorial tutoring of an international volunteer internship
Coorientador de Aline Kuster
BSc Biomedical Engineering (Iniciação científica)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2017/02 - Atual BSc Biochemistry - Project Report
Orientador de Débora Mena
BSc Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2017/02 - Atual Volunteer internship
Orientador de Carolina Santos
BSc Biochemistry (Iniciação científica)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2016/02 - Atual BSc Biochemistry - Project Report
Orientador de Maria Inês Alves
BSc in Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2015/02 - Atual BSc Biochemistry - Project Report
Orientador de Cláudia Soares de Almeida
BSc Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2012 - 2021/11/23 Exendin-4 therapy in Alzheimer’s disease and diabetic brain: effect in mitochondria and insulin-mediated pathways
Orientador de Emanuel Monteiro Candeias
PhD Programme in Experimental Biology and Biomedicine (PDBEB) (Doutoramento)
CNC.IBILI, Portugal
2021/01/03 - 2021/01/31 Laboratory Rotation
Orientador
MSc in Cellular and Molecular Biology (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2020/01/03 - 2020/08/31 Volunteer BSc Researcher
Orientador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2020/06 - 2020/07 Volunteer Summer Internship
Orientador
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2020/06 - 2020/07 Volunteer Summer Internship
Orientador
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2020/02/01 - 2020/02/29 MSc in Biomedical Research (MIB) - Lab Rotation
Orientador de Carolina Santos
MSc in Biomedical Research (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2019/06 - 2019/07 Volunteer Summer internship
Orientador de Rita Gageiro
BSc Biology (Iniciação científica)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2019/02 - 2019/07 Supervision of BSc student - Project
Orientador de Inês Rodrigues
Unidade Curricular Projecto - BSc in Biology (Licenciatura/Bacharelato)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2018/09 - 2019/07 Laboratorial tutoring of MSc student
Coorientador de Vera Martinho Pais
MSc (Mestrado)
Universidade de Aveiro Departamento de Biologia, Portugal
2018/11 - 2019/01 BSc Biology - Volunteer internship
Orientador de Inês Alexandra Rodrigues
BSc (Iniciação científica)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2018/09/01 - 2019 N/A (under embargo period)
Orientador de Maria Inês Alves
Master in Molecular & Cell Biology (MBCM) (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/09/01 - 2019 N/A (under embargo period)
Orientador de Débora Tatiana Mena
Master in Molecular & Cell Biology (MBCM) (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2018/09/01 - 2018/10/31 MSc Research Fellow - Lab tutoring
Coorientador de Tiffany Santos Pinho
MSc Research Fellow (Outra)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/09 - 2018/08 Volunteer internship
Orientador de Maria Inês Alves
BSc Biochemistry (Iniciação científica)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2018/02 - 2018/07 BSc Biochemistry - Project Report
Orientador de Maria Beatriz da Silva
Unidade Curricular Projecto - BSc in Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2018/05/14 - 2018/06/08 Master in Cellular and Molecular Biology (MBCM) - Lab Rotation - International ERASMUS student
Orientador de Chiara Cioccarelli
MSc (Curso de aperfeiçoamento / especialização)
Università degli Studi di Padova, Itália
2018/03/01 - 2018/03/31 Master in Cellular and Molecular Biology (MBCM) - Lab Rotation
Orientador de Débora Mena
MSc (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2018/01/15 - 2018/02/15 Master in Cellular and Molecular Biology (MBCM) - Lab Rotation
Orientador de Maria Inês Alves
MSc (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2014 - 2018 Post-Doctoral Fellowship from FCT
Coorientador de Brígida Pinho
Post-Doctoral Fellowship (Outra)
REQUIMTE LAQV Porto, Portugal
2017/07/01 - 2017/07/31 Volunteer Summer internship
Coorientador de Inês Santos
BSc Biochemistry (Iniciação científica)
Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal
2017/02 - 2017/07 BSc Human Biology - Project Report
Coorientador de Joana Faria
Unidade Curricular Projecto - BSs in Human Biology (Licenciatura/Bacharelato)
Universidade de Évora Centro de Investigação em Ciências e Tecnologias da Saúde, Portugal
2017/03/27 - 2017/04/21 Master in Biomedical Research (MIB) - Lab Rotation
Orientador de Cátia Lopes
MSc (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/07/11 - 2016/07/22 Volunteer Summer internship - “Estágios Nacionais 2016”, organized by the “ANEM - Associação Nacional de Estudantes de Medicina”.
Orientador de Natacha Cardoso Ladeira
BSc in Medicine (Iniciação científica)
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2015/01 - 2016/03 Volunteer internship
Orientador de Inês Carolina Sebastião
MSc Biochemistry (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2015/06 - 2015/08 Volunteer Summer internship
Orientador de Maria Inês Alves
BSc in Biochemistry (Iniciação científica)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2015/06 - 2015/08 Volunteer Summer internship
Orientador de Ana Beatriz Ferreira
BSc in Biochemistry (Iniciação científica)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2014/09 - 2015/08 Volunteer internship - Lab tutor
Coorientador de João Mendes
PhD (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra, Portugal
2014/09 - 2015/08 Volunteer internship - Lab tutor
Coorientador de Diogo Verde
BSc (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2010 - 2015/04/28 Type 2 diabetes and infertility: the role of sex hormones and metabolic dysfunction in Sertoli cells
Coorientador de Luís Pedro Ferrreira Rato
Universidade da Beira Interior Faculdade de Ciências da Saúde, Portugal
2014/07/01 - 2014/11/29 Research Technician Fellow (BTI, MSc)
Orientador de Inês Carolina Sebastião
MSc (Outra)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/07/14 - 2014/07/25 "Ciência no Verão" Summer internship - Highschool students
Coorientador de Three highschool students
Ciência Viva, Portugal
2013/09/01 - 2014/07 Brain Dysfunction and Cell Death in Type 2 Diabetes: A neuroprotective role for the peripheral treatment with Exendin-4
Orientador de Inês Carolina Sebastião
Master in Biochemistry (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013/01/01 - 2014/04/30 Research Technician Fellow (BTI, BSc)
Orientador de Susana Cardoso
BSc (Outra)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/01/01 - 2014/01/29 Master in Cellular and Molecular Biology (MBCM) - Lab Rotation tutoring
Coorientador de Rui Gomes
MSc (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2013/01/28 - 2013/02/22 Inter-University Doctoral Programme in Ageing and Degeneration of Complex Biological Systems - Lab rotation tutoring
Coorientador de Diogo Silva
PhD (Curso de aperfeiçoamento / especialização)
Universidade Nova de Lisboa Escola Nacional de Saúde Pública, Portugal
2012/01/03 - 2012/01/31 Neurasmus Mundus Masters Programme - Lab rotation tutoring - International student
Coorientador de Bérangère Lucotte
MSc (Curso de aperfeiçoamento / especialização)
2012/01/03 - 2012/01/31 Neurasmus Mundus Masters Programme - Lab rotation tutoring - International student
Coorientador de Tamrat Meshka
MSc (Curso de aperfeiçoamento / especialização)
2011/05 - 2011/08 BSc Biotechnology - Project Report
Orientador de Sara Cristina Costa Santos
BSc Biotechnology (Licenciatura/Bacharelato)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2011/03 - 2011/07 Integrated MSc in Medicine - Initiation to Research
Coorientador de Bárbara Marques
MSc (Iniciação científica)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011/03 - 2011/07 Integrated MSc in Medicine - Initiation to Research
Coorientador de André Jorge
MSc (Iniciação científica)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011/03 - 2011/07 Integrated MSc in Medicine - Initiation to Research
Coorientador de André Teixeira
MSc (Iniciação científica)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011/03 - 2011/07 MSc in Biomedical Research (MIB) - Lab Rotation
Coorientador de Diana Lourenço Matias
MSc (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra Faculdade de Medicina, Portugal
2011/03 - 2011/07 MSc in Biomedical Research (MIB) - Lab Rotation
Coorientador de Gisela Santos
MSc (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra Faculdade de Medicina, Portugal
2009/09/01 - 2011/01 ROLE OF INSULIN AND IGF-1 IN ENERGY METABOLISM IN HUNTINGTON’S DISEASE: STUDIES IN CORTICAL AND STRIATALNEURONS FROM YAC128 TRANSGENIC MICE AND HUMAN LYMPHOBLASTS
Coorientador
Master in Biotechnology for Health Sciences (Mestrado)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2009/09/01 - 2010/07 Peripheral and cerebral metabolic features in an animal model of Huntington’s disease expressing full-length mutant huntingtin
Coorientador de Carla Lopes
Integrated Master in Biomedical Engineering (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2010/02 - 2010/06 Volunteer internship
Coorientador de Patrícia Guarino
BSc (Iniciação científica)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2010/02 - 2010/04 MSc in Cellular and Molecular Biology (MBCM) - Lab rotation
Coorientador de Marcelo Correia
MSc (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2010/02 - 2010/04 MSc in Cellular and Molecular Biology (MBCM) - Lab rotation
Coorientador de Daniel Santos
MSc (Curso de aperfeiçoamento / especialização)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2017/12/21 - Atual Invited by the Organizing Committee of the 2nd 1st Meeting on Biomedical Research @ UC (Coimbra, Portugal) to moderate, together with Doctors Vilma Sardão and Flávio Reis, the session: Metabolism, Aging & Disease. (2017/12/21)
Encontro (Outra)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2003/05 - Atual Scientific Committee of the Postgraduated Course: Mitochondrial Bioenergetics: Uncoupling Proteins and Aplications in Experimental Toxicology, that occurred in Zoology Department, FCTUC, University of Coimbra, Coimbra, Portugal. (2003/05/26 - 2003/05/31)
Outro (Membro da Comissão Científica)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2021/02 - 2021/12 I was invited to be a Guest Editor of the International Journal of Molecular Sciences (IF: 4.556) and to organize a Special Issue on Energy Metabolites in Neural Cells, which will be published in 2021. (2021/02)
Outro
2011/12/05 - 2011/12/09 Advanced course on Neuroendocrinology & Neuromodulation, from the PDBEB (CNC, Coimbra, Portugal) (2011/12/05)
Outro (Coorganizador)
2008/03/09 - 2008/03/14 Integrated the Organizing Committee of Brain Awareness Week 2008 (March 9th-14th 2008), by CNC, and participated also in scientific divulgation activities with school students. (2008/03/09 - 2008/03/14)
Outro (Coorganizador)

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2020/09/11 - Atual European Huntington’s Disease Network (EHDN) Virtual Bridging Event - EHDN2020, organized by EHDN.
2019/10/30 - Atual PostDoc@UC – 30/10/2019 – Skills for the Future and Management of soft skills workshop (Prof. Wander Carvalho, Coimbra Business School, ICAC) – Dep Eng Civil, UC
Encontro
2019/10/18 - Atual Online course on Experimental Methods in Systems Biology, organized by Marc Birtwistle, from the Icahn School of Medicine at Mount Sinai, USA and the online platform for Advanced Courses Coursera, started on October 18th 2019. Aim: update and complement knowledge on scientific paper writing. So far, completed 3 online courses with certification.
Outro
2019/05/06 - Atual In May 6th 2019, participated in Science outreach activities to students from Elementary School (8-9 years old), integrated in the Escola Ciência Viva, organized by Ciência Viva Rómulo de Carvalho and CNC
Outro
2018/11/28 - Atual In November 28th 2018, participated in Science outreach activities to students from Elementary School (8-9 years old), integrated in the Escola Ciência Viva, organized by Ciência Viva Rómulo de Carvalho and CNC
Outro
2018/05/22 - Atual Course on Gestão de Resíduos Hospitalares Perigosos – Triagem e Acondicionamento, organized by the CNC, Ambiwaste and AmbiPombal, May 22nd 2018. Duration: 90 min
Oficina (workshop)
2017/11 - Atual Online course on Research Writing Skills, organized by the College of Skills Training from the Elsevier Publishing Campus, started on November 2017. Aim: update and complement knowledge on scientific paper writing. So far, completed 3 online courses with certification.
Outro
2017/02 - Atual Volunteer work: Member of the Informal Caregiver Volunteers group from the ¿EU no MusEU¿ program, organized by the National Museum Machado de Castro (Coimbra, Portugal). This program is co-organized with the support of Alzheimer¿s Portugal and Neurology Clinic (Centro Hospitalar e Universitário de Coimbra), and aims at provide intellectual and sensorial stimulation of Alzheimer¿s disease and dementia patients, as well as to their home caregivers, through the contact with Art and History.
Outro
2015/09 - Atual Advanced Course on Swedish Legislation, Ethics and Animal Use, organized by the Faculty of Medicine, Lund University (Lund, Sweden), September 2015. Aim: complement the European Creditation by FELASA (Category C) and handle with laboratory animals in Swedish Animal Facilities (EU Directive (2010/63).
Outro
2014/02/20 - Atual Seahorse Course, organized by CNC, February 20th – 21st 2014
Outro
2010/05/14 - Atual In May 14th 2010, participated in science divulgation activities at Feira da Ciência do Pinhal Interior (Proença-a-Nova, Portugal), integrated in CNC team
Outro
2009/01/22 - Atual Webminar: Achieving higher throughput and greater content when measuring mitochondrial function, presented by Professor David Ferrick, integrated in web-based conferences supported by Seahorse Bioscience, January 22nd 2009
Outro
2008/12/08 - Atual Webminar: The Rate and Coupling Efficiency of Oxidative Phosphorylation in Mitochondria and Cells, presented by Professor Martin Brand, integrated in web-based conferences supported by Seahorse Bioscience, December 8th 2008
Outro
2008/11/12 - Atual Workshop in Oral Presentation, organized by Professor Patrik Brundin (Faculty of Medicine, Lund University, Lund, Sweden), November 12th 2008
Oficina (workshop)
2008/11/11 - Atual Webminar: The Response of the Mitochondrion to Oxidative Stress in Cardiovascular Cells, presented by Professor Victor Darly-Usnar, integrated in web-based conferences supported by Seahorse Bioscience, November 11th 2008
Outro
2008/10/10 - Atual Workshop on Seahorse technique, that occurred at Faculty of Medicine, Lund University (Lund, Sweden), October 10th 2008.
Oficina (workshop)
2004/09 - Atual Free Radical School 2004: Free Radicals and diseases – Gene expression, cellular metabolism and pathophysiology (Spetses, Greece, September 20th – October 1st 2004)
Outro
2004/07 - Atual 17. FEBS Postgraduate Course: New molecular strategies to treat neurodegenerative diseases (Ofir, Portugal, July 17th – 23rd 2004).
Outro
2004/01 - Atual 18. Advanced Course on Biologia da Morte Celular II – Regulação da Apoptose (Lisboa, Portugal, January 12th – 16th 2004).
Outro
2003/04 - Atual Workshop: Physiological Society Spring Workshop and Hungarian Academy of Sciences - Receptors and Cell Signalling in Oxidative Stress (Budapest, Hungary, April 3rd – 5th 2003).
Oficina (workshop)
2002/10 - Atual Symposium: 3rd Neurobiology of Aging Conference 2002, organized by Society for Neuroscience (Orlando, CA, USA, October 30th – November 1st 2002).
Simpósio
2002/09 - Atual Advanced Course: Hormone-dependent organization of the brain, organized by Instituto de Investigação em Ciências da Vida e da Saúde (University of Minho, Braga, Portugal, September 30th - October 4th 2002).
Outro
2002/09 - Atual Advanced Course: Novel Therapeutic Opportunities in Neurodegenerative Diseases, organized by Centro de Biologia Celular (University of Aveiro, Aveiro, Portugal, September 12th – 13th 2002)
Outro
2001/10 - Atual Advanced Course: Stereotaxic Surgery for Rodent Models of Neurodegeneration and Repair, organized by CNC, October 15th- 19th 2001.
Outro
2001/09 - Atual FEBS Advanced Course: Mitochondria in Cell Life and Death (Moscow, Russia, September 2nd – 7th 2001).
Outro
2001/07 - Atual Advanced Course: A Practical Course on Identification of Apoptosis: Mitochondrial Pathway (Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal, July 9th – 13th 2001).
Outro
2001/06 - Atual Advanced Course Oxidative Stress: From Basic Science to Medicine, organized by CNC, June 18th – 20th 2001
Outro
2001/05 - Atual Advanced Course Mechanisms of Mitochondrial Toxicity, organized by CNC, May 21st – 23th 2001
Outro
2000/07 - Atual Advanced Course: Bioenergética Mitocondrial: Investigação Fundamental e Uso em Toxicologia Experimental, organized by CNC, from July 12th – 23rd 2000 (30h theoretical + 50h practical classes).
Outro
2000/06 - Atual Workshop on Cell Death (IBMC, Porto, Portugal, June 10th – 11th 2000).
Oficina (workshop)
2000/04 - Atual Advanced Course Organotypic culture of hippocampal slices, organized by CNC, from April 10th – 14th 2000 (6h theoretical + 30h practical classes).
Outro
2020/11/24 - 2020/12/08 EIT Health Summit Series https://www.summit.eithealth.eu/?utm_source=email&utm_medium=email&utm_campaign=confirmation_register_free_event
2020/11/17 - 2020/11/20 EIT Health Virtual Matchmaking 2020 https://eithealth.eventscase.com/mt/eithealthmatchmaking2020
Encontro
2020/11/12 - 2020/11/12 European Animal Research Association (EARA) Media Training on Communication of Animal Research Studies. November 12th 2020. https://www.eventbrite.co.uk/e/eara-media-training-portugal-tickets-121378527443. Theoretical-practical course (3h), organized by European Animal Research Association (EARA).
2020/10/25 - 2020/10/26 21st International Conference on Alzheimer's Drug Discovery. Virtual Meeting, organized by the Alzheimer's Drug Discovery Foundation. https://meetings.alzdiscovery.org/alz-virtual-meeting/
2020/09/20 - 2020/09/30 54th ESCI Annual Scientific Meeting - COVID-19 Online Edition, organized by the European Society for Clinical Investigation
2020/09/23 - 2020/09/23 International COVID-19 Webinar: current scenario, opportunities and challenges', organized by Instituto de Biomedicina (Universidade de Aveiro) and Instituto de Ciências Biomédicas Abel Salazar (Porto)
2020/04/01 - 2020/05/31 Volunteer work at COVID-19 Diagnoses at UC - Aim: To perform COVID-19 diagnosis in samples collected by the Portuguese Health Authorities in the population during the first wave of the COVID-19 pandemic. I was responsible for viral inactivation of the samples, performed in a Class II Type A1 Biosafety Laboratory, to increase their safety before extraction for qRT-PCR.
Outro
Universidade de Coimbra, Portugal
2016 - 2020 Since 2016, participates in Science outreach activities (e.g. Open Lab visits) integrated in the Science & Technology Week, organized by CNC and Science Museum of Coimbra.
Outro
2009 - 2020 Since 2009 to date, participates in Science outreach activities integrated in the European Researchers’ Night, organized by the Science Museum of Coimbra and CNC.
Outro
2005 - 2020 Since 2005 to date, participates in science outreach activities integrated on Brain Awareness Week, organized by CNC
Outro
2011/05/23 - 2011/05/23 Biostatistics Course, organized by CNC, May 23rd – 26th 2011
Outro
2010/04/19 - 2010/04/30 Advanced Course on Laboratory Animal Science, organized by CNC and Faculty of Medicine, University of Coimbra and Instituto de Biologia Molecular e Celular (University of Porto, Porto, Portugal), April 19th – 30th 2010 (80 hours). Aim: obtain European Accreditation to handle with laboratory animals as a Principal Investigator in Animal Experimentation (Category C), according to Federation of European Laboratory Animal Sciences Associations (FELASA).
Outro
2009/03/02 - 2009/06/06 Web-based Advanced Course: English for scientific writing, organized by Professor Rowena Jansson (Kalmar University, Kalmar, Sweden), March 2nd – June 6th 2009.
Outro
2009/05/03 - 2009/05/06 Biobusiness Course, organized by Professor Patrik Brundin and Doctor Srikanth Rangananthan (Faculty of Medicine, Lund University, Lund, Sweden), May 3rd – 6th 2009.
Outro
2007 - 2008 - During 2007-2008 was a volunteer at Casa do Pai, Fundação Bissaya Barreto (Coimbra, Portugal). I was the tutor of a 11-year-old institutionalized boy, supporting him with studies and making him enjoying to learn, the school and life.
Outro

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2020/12/16 N/A (Thesis under embargo period)
Arguente principal
Tânia Raquel Pereira Soares (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/07/23 Projeto em Biologia Aplicada ll, BSc in Biology, University of Coimbra.
Arguente principal
João Cancela Lourenço da Silva Vitória (Outro)
2019/07/23 N/A (Thesis under embargo period)
Orientador
Débora Mena (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2019/07/17 N/A (Thesis under embargo period)
Arguente principal
Sara Daniela Reis (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2019/07/14 N/A (Thesis under embargo period)
Orientador
Maria Inês Alves (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2018/09/10 N/A (Thesis under embargo period)
Arguente principal
Liliana Rodrigues Dias (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2018/07/19 N/A (Thesis under embargo period)
Arguente principal
Diogo Malheiro Passos (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2017/09/20 N/A (Thesis under embargo period)
Arguente principal
Rafael Carecho (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2016/10/28 N/A (Thesis under embargo period)
Arguente principal
Daniela Mendes (Mestrado)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2016/09/22 N/A (Thesis under embargo period)
Arguente principal
Daniela Costa (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2014/09/11 N/A (Thesis under embargo period)
Arguente principal
Joana Portela (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2014/07/14 N/A (Thesis under embargo period)
Orientador
Inês Carolina Sebastião (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2013/07/16 N/A (Thesis under embargo period)
Arguente
Susana Maria Batista Tieres Tomé Cardoso (Doutoramento)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2012/04/24 BSc Final Report defence
Orientador
Sara Costa Santos (Outro)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2011/01/13 N/A (Thesis under embargo period)
Arguente principal
Maria João Ribeiro (Mestrado)
Universidade de Trás-os-Montes e Alto Douro Escola de Ciências da Vida e do Ambiente, Portugal
2010/10/10 BSc Final Report defence
Arguente principal
Anabel Rodriguez (Outro)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2010/07/23 N/A (Thesis under embargo period)
Vogal
Carla Nunes Lopes (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2019/11 - Atual International Journal of Molecular Sciences (1422-0067) MDPI AG
2019/10 - Atual Current Alzheimer Research (1567-2050) Bentham Science
2016/06 - Atual International Journal of Rare Diseases & Orphan Drugs
2012/12 - Atual Peer J
2011/01 - Atual International Journal of Research in Phytochemistry & Pharmacology
2009/04 - Atual Frontiers in Aging Neuroscience (1663-4365) Frontiers Media SA

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2021/01 - Atual Juri of an international selection tender procedure for a MSc hiring (ERA Careers unique identifier: 5e628e89-8dc3-4d32-ba22-db6a0222152b) integrated in the FCT-funded project MitoScreening- PTDC/BTM-SAL/29297/2017, that is ongoing at CNC.
2020/12 - Atual Juri of an international selection tender procedure for a PhD hiring (ERA Careers unique identifier: 781d5a9f-668e-401f-ba13-83d00e25d1e8) integrated in the FCT-funded project iPS cells-derived exosomes - impact on mitochondrial (dys)function in Huntington's disease and potential nanodelivery system for microRNA-based therapeutics (POCI-01-0145-FEDER-029621), that is ongoing at CNC.
2019/10 - Atual Juri of Research Fellowship Applications Research Fellowship for Master (BIM) application #1 integrated in the EU-funded project Healthy Aging 2020 (CENTRO-01-0145-FEDER-000012)
Avaliador
Universidade de Coimbra Faculdade de Medicina, Portugal
2019/10 - Atual Juri of Research Fellowship Applications Research Fellowship for Master (BIM) application #2 integrated in the EU-funded project Healthy Aging 2020 (CENTRO-01-0145-FEDER-000012)
Avaliador
Universidade de Coimbra Faculdade de Medicina, Portugal
2019/05 - Atual Jury of an international selection tender procedure for a PhD hiring (ERA Careers unique identifier: e20a875d-e1d7-4c30-9a7e-8be48d6786fa) integrated in the FCT-funded project iPS cells-derived exosomes - impact on mitochondrial (dys)function in Huntington's disease and potential nanodelivery system for microRNA-based therapeutics (POCI-01-0145-FEDER-029621).
Avaliador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2019/05 - Atual Revision of Abstracts/Poster Evaluation in Scientific Meetings Invited by the Organizing Committee of the 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI2019) (Coimbra, Portugal, May 22nd – 24th 2019) to be the president of the jury that evaluated poster communications presented at the Symposium 8 – Neurobiology of Aging for final prizes
Avaliador
2019/05 - Atual Revision of Abstracts/Poster Evaluation in Scientific Meetings Invited by the Organizing Committee of the 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI2019) (Coimbra, Portugal, May 22nd – 24th 2019) to evaluate poster communications presented at the Symposium 10 – Other Topics: Clinical for final prizes.
Avaliador
2019/01 - Atual Juri of Research Fellowship Applications Research Fellowship for Master (BIM) application integrated in the EU-funded project Healthy Aging 2020 (CENTRO-01-0145-FEDER-000012)
Avaliador
Universidade de Coimbra Faculdade de Medicina, Portugal
2018/10 - Atual Jury of a Post-Doctoral Fellowship application integrated in the EU-funded project Healthy Aging 2020 (CENTRO-01-0145-FEDER-000012).
Avaliador
Universidade de Coimbra Faculdade de Medicina, Portugal
2018/05 - Atual Evaluator of project applications Contribution, as international reviewer expert, for the peer-revision and evaluation of a Research Project submitted to “Biomedicine & Health Sciences Area; Basic Medical Sciences Field” in their national Call for Proposals
Especialista
Hrvatska Zaklada za Znanost, Croácia Hrvatska Zaklada za Znanost
2018/03 - Atual Evaluator of project applications Contribution, as international reviewer expert, for the peer-revision and evaluation of a Research Project submitted to “Physiologie et Physiopathologie Area” in their national Call for Proposals
Especialista
Agence nationale de la recherche, França
2017/09 - Atual Juri of Research Fellowship Applications Research Fellowship for Master (BIM) application integrated in the EU-funded project Healthy Aging 2020 (CENTRO-01-0145-FEDER-000012)
Avaliador
Universidade de Coimbra Faculdade de Medicina, Portugal
2017/09 - Atual Jury of a Research Fellowship for a Licenciate (BIL) application integrated in the FCT-funded project Proteostasia da huntingtina e mitocôndria: alvos para prevenir a disfunção neuronal na doença de Huntington (PTDC/NEU-NMC/0412/2014), that occurred at ICETA (University of Porto, Porto, Portugal; reference: ICETA 2017-21).
Avaliador
Universidade do Porto Faculdade de Farmácia, Portugal
2016/11 - Atual Evaluator of project applications Contribution, as international reviewer expert, for the peer-revision and evaluation of a Research Project submitted to “Biomedicine & Health Sciences Area; Basic Medical Sciences Field” in their national Call for Proposals
Especialista
Hrvatska Zaklada za Znanost, Croácia Hrvatska Zaklada za Znanost
2014/05 - Atual President of the juri in the Research Fellowship (BI) application integrated in her FCT-funded project The impact of exendin-4 therapy in the molecular mechanisms underlying type 2 diabetes-related long-term brain dysfunction (PTDC/SAU-TOX/117481/2010).
Especialista
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013/10 - Atual Revision of Abstracts/Poster Evaluation in Scientific Meetings Invited by the Organizing Committee of the 4th PF2MUC Meeting (Coimbra, Portugal, October 25th 2013) to review and select submitted abstracts for oral or poster communication presentation, as well as to evaluate oral and poster communication for final prizes
Avaliador
2012/12 - Atual President of the juri in the Research Fellowship (BI) application integrated in her FCT-funded project The impact of exendin-4 therapy in the molecular mechanisms underlying type 2 diabetes-related long-term brain dysfunction (PTDC/SAU-TOX/117481/2010).
Especialista
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2020/11 - Atual In January 21st 2021 I taught in the Modular Structure Training in Laboratory Animal Science ¿ Rodents, According to 2010/63/EU Directive, co-organized by CNC.IBILI Consortium, Faculty of Medicine ¿ University of Coimbra and CIMAGO. This advanced course was held at the Faculty of Medicine ¿ University of Coimbra (Coimbra, Portugal). My deeper involvement occurred in theoretical and practical classes from Module 22. Course / Discipline taught since 2019
2019/12 - Atual In February 13th 2020 taught in the Modular Structure Training in Laboratory Animal Science – Rodents, According to 2010/63/EU Directive, co-organized by CNC.IBILI Consortium, Faculty of Medicine – University of Coimbra and CIMAGO. This advanced course was held at the Faculty of Medicine – University of Coimbra (Coimbra, Portugal). Her deeper involvement occurred in theoretical and practical classes from Module 22.
2019/12 - Atual In February 20th 2020 taught in the Modular Structure Training in Laboratory Animal Science – Rodents, According to 2010/63/EU Directive, co-organized by CNC.IBILI Consortium, Faculty of Medicine – University of Coimbra and CIMAGO. This advanced course was held at the Faculty of Medicine – University of Coimbra (Coimbra, Portugal). Her deeper involvement occurred in theoretical and practical classes from Module 22.
2019/10 - Atual In January 12th 2020 taught in the Modular Structure Training in Laboratory Animal Science – Rodents, According to 2010/63/EU Directive, co-organized by CNC.IBILI Consortium, Faculty of Medicine – University of Coimbra and CIMAGO. This advanced course was held at the Faculty of Medicine – University of Coimbra (Coimbra, Portugal). Her deeper involvement occurred in theoretical and practical classes from Module 22.
2019/02 - Atual In February 2019 contributed to the course Research Challenges in Cellular Biology/Neurobiology and Biomedicine, from the MSc in Cellular and Molecular Biology (FCTUC, Coimbra), newly implemented by Professor Ana Luísa Carvalho. Her task consisted in raising the awareness among her MSc students Débora Mena and Maria Inês Alves about the implications, limits and challenges of their own research work, and of the scientific research in Cellular Biology/Neurobiology and Biomedicine in general: ethical issues; translational potential and limitations;...
2019/01 - Atual In January 17th 2019 taught in the Modular Structure Training in Laboratory Animal Science – Rodents, According to 2010/63/EU Directive, co-organized by CNC.IBILI Consortium, Faculty of Medicine – University of Coimbra and CIMAGO. This advanced course was held at the Faculty of Medicine – University of Coimbra (Coimbra, Portugal). Her deeper involvement occurred in theoretical and practical classes from Module 22.
2019/01 - Atual In March 8th 2019 taught in the Modular Structure Training in Laboratory Animal Science – Rodents, According to 2010/63/EU Directive, co-organized by CNC.IBILI Consortium, Faculty of Medicine – University of Coimbra and CIMAGO. This advanced course was held at the Faculty of Medicine – University of Coimbra (Coimbra, Portugal). Her deeper involvement occurred in theoretical and practical classes from Module 22.
2019/01 - Atual In April 4th 2019 taught in the Modular Structure Training in Laboratory Animal Science – Rodents, According to 2010/63/EU Directive, co-organized by CNC.IBILI Consortium, Faculty of Medicine – University of Coimbra and CIMAGO. This advanced course was held at the Faculty of Medicine – University of Coimbra (Coimbra, Portugal). Her deeper involvement occurred in theoretical and practical classes from Module 22.
2019/01 - Atual In May 27th 2019 taught in the Modular Structure Training in Laboratory Animal Science – Rodents, According to 2010/63/EU Directive, co-organized by CNC.IBILI Consortium, Faculty of Medicine – University of Coimbra and CIMAGO. This advanced course was held at the Faculty of Medicine – University of Coimbra (Coimbra, Portugal). Her deeper involvement occurred in theoretical and practical classes from Module 22.
2018/11/26 - Atual In November 26th 2018 was invited by Professor Emília Duarte to present a talk on LabTalks, from the Master in Cellular and Molecular Biology (MBCM, FCTUC, University of Coimbra, Coimbra, Portugal). Her talk was intitled: Brain hormone signaling, dysmetabolism & sexual aging: The Bermuda Triangle in Alzheimer’s disease & type 2 diabetes?
2017/10/26 - Atual In October 26th 2017 was invited by Professor Emília Duarte to present a talk on LabTalks, from the Master in Cellular and Molecular Biology (MBCM, FCTUC, University of Coimbra, Coimbra, Portugal). Her talk was intitled: Brain hormone signaling, dysmetabolism & sexual aging: The Bermuda Triangle in Alzheimer’s disease & type 2 diabetes?
2016/11/10 - Atual In November 10th 2016, was invited by Doctors Cláudia Pereira and Henrique Girão to teach in the course on Research Methods & Techniques, from the Master in Biomedical Research (MIB, FMUC, University of Coimbra, Coimbra, Portugal). Her lecture was intitled: Type 2 diabetes & Alzheimer disease: does sex matter?
2016/10 - Atual In October 2016, was invited by Doctors Henrique Girão and Cláudia Pereira to collaborate in activities related with the course on Research Methods & Techniques, from the PhD Programme in Health Sciences (FMUC, University of Coimbra, Coimbra, Portugal).
2013/05/16 - Atual In May 16th 2013, was invited by Professor Sandra Morais Cardoso to teach at the discipline of Biology of Aging, from the Integrated Master Programme in Biomedical Engineering (FCTUC, University of Coimbra, Coimbra, Portugal). The lecture was intitled: Effect of gender on brain aging.
2011/12/08 - Atual In December 5th-9th 2011, co-organized and taught at the advanced course on Neuroendocrinology & Neuromodulation, from the PDBEB (CNC, Coimbra, Portugal). The lecture was intitled Periphery-CNS crosstalk: when insulin challenges an old paradigm (December 8th).
2011/12/05 - Atual In December 5th-9th 2011, co-organized and taught at the advanced course on Neuroendocrinology & Neuromodulation, from the PDBEB (CNC, Coimbra, Portugal). The lecture was intitled Diabetes mellitus: more than a peripheral metabolic disease (December 5th).
2010/11/16 - Atual In November 16th 2010, was invited by Professors Paula Moreira and Sandra Morais Cardoso to teach at the advanced course: Biology of Aging, from the PDBEB (CNC, Coimbra, Portugal). The lecture presented was intitled: Oxidative Stress in Aging.
2010/04 - Atual In April 2010 I was invited to teach practical classes on Brain Dissection and Morphology of the Neurosciences discipline for students of Integrated Masters on Medicine (FMUC, University of Coimbra, Coimbra, Portugal).
2010/03 - Atual In March 2010 I was invited by Doctor Paulo Pereira to collaborate in activities related with the course on Research Methods & Techniques, from the PhD Programme in Health Sciences (FMUC, University of Coimbra, Coimbra, Portugal).
2009/11 - Atual In November 2009 I was invited to teach practical classes on Brain Dissection and Morphology of the Neurosciences discipline for students of Integrated Masters on Medicine (FMUC, University of Coimbra, Coimbra, Portugal).
2008/04 - Atual In April 2008 I was invited to teach practical classes on Neurobiology of Glutamate Receptors of the Neurosciences discipline for students of Integrated Master on Medicine (FMUC, University of Coimbra, Coimbra, Portugal).
2021/03/08 - 2021/03/12 In March 8th-12th 2021 I will teach at the CNC Advanced Course 2021 Metabolic Remodeling in Health and Disease: From Molecules to Organelle to Society, from the Doctoral Program in Experimental Biology and Biomedicine (PDBEB). This Course is organized by Doctor Paulo J. Oliveira and Professor João Ramalho-Santos. My lecture entitled: Brain (Dys)Metabolism in Cardiovascular Risk and (Reproductive) Aging" will be presented on March 11th. (Curso de doutoramento (conclusão de unidades curriculares))
2021/01/20 - 2021/01/20 In January 20th 2021 I taught at the Workshop Fundamentals of Cellular and Molecular Metabolism: Relevance for Health and Disease, co-organized by the CNC and ITMO University (St. Petersburg, Russia). My lecture was entitled: Data and Statistical Analysis: Basic Concepts and Applications.
2020/08 - 2020/10 From August 3rd-October 31th 2020 I was involved, together with Doctor Paulo Oliveira¿s team in the Summer Course "Verão com Ciência", organized by CNC, IIIUC, DGES and FCT. This Course included several fellowships from FCT. Besides helping in the laboratorial supervision of the fellows, I presented three lectures, entitled: "Metabolism: Basic notions, examples & other considerations", "The Art of Data Analysis", and "The Art of (Brain) Aging" were presented on August 26th, September 17th and October 14th.
2020/02/07 - 2020/02/28 From February 7th-28th 2020 was involved, together with Doctor Paulo Oliveira¿s team in the Experimental Advanced Course in Biomedicine: Mitochondria and Disease, that will be held to students from High School until Masters Programmes and teachers, once/week at the Instituto de Educação e Cidadania (IEC, Mamarrosa, Oliveira do Bairro, Portugal), at the Escola Secundária Adolfo Portela, Águeda. Her lecture intitled: Doenças neurodegenerativas e mitocôndria: Morte celular e autofagia was presented on February 21st.
2019/10 - 2020/02/20 In December 2nd 2019 taught in the Modular Structure Training in Laboratory Animal Science – Rodents, According to 2010/63/EU Directive, co-organized by CNC.IBILI Consortium, Faculty of Medicine – University of Coimbra and CIMAGO. This advanced course was held at the Faculty of Medicine – University of Coimbra (Coimbra, Portugal). Her deeper involvement occurred in theoretical and practical classes from Module 22. (Outros)
2019/04/27 - 2019/06/01 From April 27th to June 1st 2019 was involved, together with Doctor Paulo Oliveira’s team in the Experimental Advanced Course in Biomedicine: Mitochondria and Disease, that will be held to students from High School until Masters Programmes and teachers, once/week at the Instituto de Educação e Cidadania (IEC, Mamarrosa, Oliveira do Bairro, Portugal). Her lecture intitled: Doenças neurodegenerativas e mitocôndria: Morte celular e autofagia was presented on May 11th
2018/01 - 2018/03 From January 27th to March 10th 2018 was involved, together with Doctors Susana Pereira, António Moreno and Paulo Oliveira in the Science in Action Course: Gestational Diabetes, that was held to students and teachers from High School, once/week at the Instituto de Educação e Cidadania (IEC, Mamarrosa, Oliveira do Bairro, Portugal). Her lecture intitled: Diabetes: de doença crónica a doença reversível was presented on February 24th.
2017/09/25 - 2017/10/09 From September 25th to October 9th 2017 taught in the Modular Structure Training in Laboratory Animal Science – Rodents, According to 2010/63/EU Directive, co-organized by CNC.IBILI Consortium, Faculty of Medicine – University of Coimbra and CIMAGO. This advanced course was held at the Faculty of Medicine – University of Coimbra (Coimbra, Portugal). Her deeper involvement occurred in theoretical and practical classes from Modules 8, 21 and 22 (September 29th and October 3rd).
2017/04/22 - 2017/05/28 From April 22nd to May 28th 2017 I was involved, together with Doctor Paulo Oliveira¿s team in the Experimental Advanced Course in Biomedicine: Mitochondria and Diseases, that was held to students from High School until Masters Programmes and teachers, once/week at the Instituto de Educação e Cidadania (IEC, Mamarrosa, Oliveira do Bairro, Portugal). My lecture was entitled: Doenças neurodegenerativas e mitocôndria: Morte celular e autofagia was presented on May 6th
2016/04/02 - 2016/05/28 From April 2nd to May 28th 2016, was involved, together with Doctor Paulo Oliveira and Professor Paula Moreira’s teams in the Experimental Advanced Course in Biomedicine: Mitochondria and Diseases, that was held to students from High School until Masters Programmes and teachers, once/week at the Instituto de Educação e Cidadania (IEC, Mamarrosa, Oliveira do Bairro, Portugal). Her lecture intitled: Morte Celular: Papel da mitocôndria e efeito de fármacos was presented on May 7th.
2015/01/10 - 2015/03/14 From January 10th to March 14th 2015, was involved, together with Doctor Paulo Oliveira and Professor Paula Moreira’s teams in the Experimental Advanced Course in Biomedicine: Mitochondria and Diseases, that was held to High School students, once/week at the Instituto de Educação e Cidadania (IEC, Mamarrosa, Oliveira do Bairro, Portugal). Her lecture intitled: Papel da mitocôndria na morte celular: efeito de fármacos was presented on February 21st.

Membro de associação

Nome da associação Tipo de participação
2020/10 - Atual Member of the EIT Health Consortium
2019/01/01 - Atual European Society for Clinical Investigation (ESCI) Member
2016/01/01 - Atual European Huntington’s Disease Network (EHDN) Member
2006/01/01 - Atual European Association for the Study of Diabetes (EASD) Member
2000/01/01 - Atual Portuguese Neuroscience Society Member
2000/01/01 - Atual Society for Neuroscience (SfN, U.S.A.) Member
1998/01/01 - Atual Portuguese Biochemistry Society (SPB) Member

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2020/11 - Atual Member of the Task Force ¿Comunicação¿ of the Metabolism, Aging and Disease Area of CIBB.
Membro
2020/11 - Atual Member of the Task Force “Financiamento e Inovação” of the Metabolism, Aging and Disease Area of CIBB.
Membro
2020/10 - Atual Member of the European Cooperation in Science and Technology (e-COST)
Outro
2017/12 - Atual Invited by the Fondation Médéric Alzheimer (a French foundation of recognized public utility) to contribute, as one of the eleven European Experts in new drug targets for Alzheimer’s disease and dementia, for the Prospective Focus Discussion on Alzheimer’s Outlook 2017: Drug targets in Alzheimer’s disease and dementia – Current and emerging avenues. This Focus Group is coordinated by Professor Bengt Winblad (Karolinska Institute, Stockholm, Sweden) and aims to present new therapeutic alternatives for the treatment of Alzheimer's disease.
Consultor
Fondation Médéric Alzheimer, França

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2018/07/18 - Atual Jury of MSc project (Monography) defence - Débora Mena Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2018/07/18 - Atual Jury of MSc project (Monography) defence - Maria Inês Alves Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2018/05/04 - Atual PhD Program MedChem Train lab rotation defence - Andreia Cunha Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2017/01 - Atual Invited by the editor of the book entitled Frontiers in Clinical Drug Research – Anti-Infectives, to review a chapter included in this book.
2016/07/21 - Atual Jury of PhD project defence - Tânia Soares Universidade do Porto Faculdade de Farmácia, Portugal
2015/07/15 - Atual Jury of PhD project defence - Sara Daniela Reis Universidade do Porto Faculdade de Farmácia, Portugal
2013/07/25 - Atual Jury of PhD project defence - Emanuel Monteiro Candeias Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal
2013/07/18 - Atual Jury of MSc project (Monography) defence - Inês Carolina Sebastião Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2013/02/06 - Atual Jury of MSc project (Monography) defence - Maria Inês Sebastião Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2009/06 - Atual Invited by the editor of the book entitled Advances in Molecular Mechanisms and Pharmacology of Diabetic Complications, to review a chapter included in this book.
2003 - Atual Revised >170 manuscripts submitted for publication to 80 journals.

Tutoria

Tópico Nome do aluno
2020/11/01 - Atual Temporary tutor of PhD student Luís Grilo
2020/11/01 - Atual Temporary tutor of MSc student Carolina Tocantins
2020/11/01 - Atual Temporary tutor of MSc student Mariana Diniz
2016/06/01 - 2016/11/30 Tutor of international MSc student Annachiara Meconi
2015/10/01 - 2016/03/31 Tutor of international PhD student Marie Sjögren
2011/09/01 - 2011/12/31 Tutor of International PhD student Elena González-Burgos
Distinções

Prémio

2020 Travel Award to participate in the Federation of European Neuroscience Societies Forum 2020 (FENS Forum 2020)
2020 Prize for the Best Flash Talk/Poster Communication (Symposium 3: Cardiovascular & Metabolic Diseases)
2019 Award for the Best New Investigator Poster Presentation, 66th Annual Meeting of the SRI2019 (Paris, France, March 12th-16th, 2019)
European Society for Reproductive Investigation (ESRI), França
2019 Prize for Best Poster Communication - Symposium 1: Mitochondria, 53rd Annual Meeting of the European Society for Clinical Investigation (ESCI2019)
European Society for Clinical Investigation, Países Baixos
2018 Prize for Best Oral Communication in Fundamental Research at the 14th Portuguese Diabetes Meeting, with the talk Diabetes and Cardiac Disease: A Heritage from intra-uterine life? 14th Portuguese Diabetes Meeting, Vilamoura, Portugal, March 9th-11th, 2018.
Sociedade Portuguesa de Diabetologia, Portugal
2018 Publons Peer Reviewer Award 2018, as one of the top 1% of peer reviewers in Neuroscience and Behavior field
2017 Publons Peer Reviewer Award 2017, as one of the top 1% of peer reviewers in Multidisciplinary field
2003 Portuguese Society of Cardiology Young Investigator Prize (team member)
Sociedade Portuguesa de Cardiologia, Portugal
2002 Servier Prize on Heart Failure (as team member), from Servier Laboratories
Sociedade Portuguesa de Cardiologia, Portugal
2002 Delta Prize on Ischemic Cardiomiopathy (as team member), from Delta Laboratories
Sociedade Portuguesa de Cardiologia, Portugal

Título

2021 Top 1% Expert in Dementia

Outra distinção

2019 ESCI2019 Meeting Travel Grant
European Society for Clinical Investigation, Países Baixos
2017 Grant to participate in the XV Meeting of the Portuguese Neuroscience Society 2017.
Portuguese Neuroscience Society, Portugal
2010 Grant to participate in the Federation of European Neuroscience Societies Meeting 2010
2010 Grant to participate in the Federation of European Neuroscience Societies Meeting 2010
Fundação para a Ciência e a Tecnologia, Portugal
2009 Grant to participate in the World Congress on Huntington’s Disease
Fundação para a Ciência e a Tecnologia, Portugal
2009 January - February 2009 - Albert Renold Young Researcher Fellowship
European Association for the Study of Diabetes, Alemanha
2008 September - December 2008 - Short-term Fellowship
Fundação Calouste Gulbenkian, Portugal
2006 Grant to participate in the 36th Annual Meeting of Society for Neuroscience
Fundação Luso-Americana, Portugal
2006 Grant to participate in the 36th Annual Meeting of Society for Neuroscience
Fundação para a Ciência e a Tecnologia, Portugal
2006 Grant to participate in the 36th Annual Meeting of Society for Neuroscience
Fundação Calouste Gulbenkian, Portugal
2005 Grant to participate in the 35th Annual Meeting of Society for Neuroscience
Fundação Luso-Americana, Portugal
2004 Grant to participate in the 2nd Spanish and Portuguese Congress on Free Radicals
Fundação para a Ciência e a Tecnologia, Portugal
2004 Grants to participate in the 34th Annual Meeting of Society for Neuroscience
Fundação Calouste Gulbenkian, Portugal
2004 Grant to participate in Free Radical School 2004 – Free radicals and disease
Federation of European Biochemical Societies, Reino Unido
2004 Grant to participate in Free Radical School 2004 – Free radicals and disease
NATO, Bélgica
2002 Grant to participate in XII Portuguese Congress of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal
2002 Grant to participate in XIth Meeting of the Society for Free Radical Research International
Fundação Calouste Gulbenkian, Portugal
2001 Grant to participate in the 27th FEBS Meeting
Sociedade Portuguesa de Bioquímica, Portugal
2001 Grants to participate in FEBS Advanced Course: Mitochondria in Cell Life and Death
Federation of European Biochemical Societies, Reino Unido
2000 Grant to participate in the XI Portuguese Congress of Biochemistry
Sociedade Portuguesa de Bioquímica, Portugal