MARIA ALICE GONÇALVES CARVALHO. Completed the Doutoramento in Doutoramento em Ciências (PhD in Science) in 1997/07/17 by Universidade do Minho Centro de Química and Licenciatura in Licenciatura em Ensino de Física e Química (Degree in Physics and Chemistry Teaching) in 1991/06/19 by Universidade do Minho. Is Assistant Professor in Universidade do Minho. Published 41 articles in journals. Has 2 section(s) of books. Has 1 patent(s) registered. Organized 4 event(s). Participated in 7 event(s). Supervised 6 PhD thesis(es). Supervised 20 MSc dissertation(s) e co-supervised 3. Has received 3 awards and/or honors. Participates and/or participated as Other in 1 project(s), Principal investigator in 2 project(s), Researcher in 9 project(s) and Supervisor in 6 project(s). Works in the area(s) of Exact Sciences with emphasis on Chemical Sciences - Organic Chemistry. Her areas of interest embrace cancer, Malaria, schizophrenia, and neglected tropical diseases such as tuberculosis, leishmaniasis and sleeping sickness. In her professional activities interacted with 222 collaborator(s) co-authorship of scientific papers. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: Project-Based Learning (PBL); Engineering Education; Industrial Engineering and Management Education; teachers¿ perceptions; student engagement; project-based learning; Engenharia e Tecnologia::Outras Engenharias e Tecnologias; Ciências Sociais::Ciências da Educação; Social Sciences; Antioxidant capacity; Voltammetric methods; Ciências Naturais::Ciências Químicas; Biomaterials; Inhalable dry powders; Magnetic drug targeting; Microparticulate systems; Remotely controlled drug release; Science & Technology; Nucleobases; Phenols; Condensations; Aldehydes; Ring closure; 6-alkoxypurines; 6-carboxamidinopurines; 6-cyanopurines; Antioxidant activity; Engineering education; Project-based learning; Active learning; Competences development; 6-enaminopurines; Imidazoles; Ethoxymethylenemalononitrile; Ethoxymethylenecyanoacetate; 6-methoxyformimidoyl purines; Malononitrile; Industrial engineering and management curriculum; Ciências Naturais::Matemáticas; NaY Zeolite; Copper(II); Imida-salen ligand; DFT studies; Alcohol oxidations; Heterogeneous catalysis; Zeolites; Copper; Oxidation; Schiff bases; Cyclic voltammetry; Structure-activity relationship; anticancer agents; Organic synthesis; Antituberculosis agents; Antioxidants; Anticancer agents; Antimicrobial agents; Adenosine receptors antagonists; Purines; Pyrimidopyrimidines; Antileishmanial agents; Phenolic derivatives; Phenolic conjugates; Organic Synthesis; Triazepines; Amidines; Diaminomaleonitrile; Branqueamento da folha de madeira; Produtos naturais; Oxidação de produtos naturais; Redução de produtos naturais; oncobiologia; anticancerígenos; Diaminomaleonitrilo; Heterociclo; cancer; Targeted therapy; Adenines; Drug carrier nanosystem; anticancer drug; Hit optimization; sustainable development; cashew nut oil; epoxy resin hardeners; cardanol; purines; pirimidopirimidinas; Heterocyclic N-oxides; imidazole; pyrrols; Pyrimidines; Radical scavengers; Anti-tuberculosis agents; Isoniazide; Purine derivatives; Pyrimidopyrimidine derivatives; Cardanol; New materials; fractalkine receptor CX3CR1; G protein-coupled receptors (GPCRs); schizophrenia; compartmentalized signaling; biased signaling; allosterism; therapeutic target; malaria; drug resistance; drug target; Antimalarial; Drug development; Pre-clinical development; Drug target; Target-based design; Ligand-based design; .

Identificação pessoal

Nome completo

Nomes de citação

  • Carvalho, Maria
  • M. Alice Carvalho
  • Carvalho, M.A.
  • Alice Carvalho

Identificadores de autor

Ciência ID
Scopus Author Id

Endereços de correio eletrónico

  • mac@quimica.uminho.pt (Profissional)


  • 253 678983 (Profissional)
  • 253604380 Ext.: 604380 (Profissional)
  • 253604386 Ext.: 604386 (Profissional)


  • Campus de Gualtar, Departamento de Química- Universidade do Minho , 4770-057 , Braga, Braga, Portugal (Profissional)


Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador independente (B2) Utilizador proficiente (C1)
Francês Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Grau Classificação
1994/03/08 - 1997/07/17
Doutoramento em Ciências (PhD in Science) (Doutoramento)
Especialização em Química (Chemistry)
Universidade do Minho Centro de Química, Portugal
"Derivados do diaminomaleonitrilo na síntese de heterociclos" (TESE/DISSERTAÇÃO)
Distinção e Louvor (Distinction and laud)
1986/09/01 - 1991/06/19
Licenciatura em Ensino de Física e Química (Degree in Physics and Chemistry Teaching) (Licenciatura)
Especialização em Ensino de Física e Química ( Physics and Chemistry Teaching)
Universidade do Minho, Portugal


Artigo em revista
  1. M. Alice Carvalho. Autor correspondente: M. Alice Carvalho. "Synthesis of Novel 2,9-Disubstituted-6-morpholino Purine Derivatives Assisted by Virtual Screening and Modelling of Class I PI3K Isoforms". Polymers 15 (2023): 1703.
    Acesso aberto • Publicado
  2. André Lopes; Nuno Santarém; Anabela Cordeiro-da-Silva; M. Alice Carvalho. "Pyrimido[5,4-d]pyrimidine-Based Compounds as a Novel Class of Antitrypanosomal and Antileishmanial Agents". ACS Medicinal Chemistry Letters (2022): https://doi.org/10.1021/acsmedchemlett.2c00170.
  3. Pedroso de Lima, Fábio; Lence, Emilio; Suárez de Cepeda, Pilar; Correia, Carla; Carvalho, M. Alice; González-Bello, Concepción; Proença, M. Fernanda. "Regioselective Synthesis of 2-Aryl-5-cyano-1-(2-hydroxyaryl)-1H-imidazole-4-carboxamides Self-Assisted by a 2-Hydroxyaryl Group". ACS Omega (2022): http://dx.doi.org/10.1021/acsomega.2c01399.
    Acesso aberto • 10.1021/acsomega.2c01399
  4. Teixeira, Sofia; Carvalho, Maria Alice; Castanheira, Elisabete M. S.. "Functionalized Liposome and Albumin-Based Systems as Carriers for Poorly Water-Soluble Anticancer Drugs: An Updated Review". Biomedicines 10 2 (2022): 486. http://dx.doi.org/10.3390/biomedicines10020486.