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Identificação

Identificação pessoal

Nome completo
Jaime Alfredo da Silva Coelho

Identificadores de autor

Ciência ID
EC1B-E9D7-0555

Endereços de correio eletrónico

  • jaimeacoelho@campus.ul.pt (Profissional)

Websites

  • www.coelhoresearchgroup.com (Profissional)
Produções

Publicações

Artigo em revista
  1. José, Maria; Faustino, Hélio; Coelho, Jaime A. S.; Vaz Pinto, Maria; Fernandes, Adelaide; companon, ismael; Corzana, Francisco; et al. "Efficient Amino-Sulfhydryl Stapling on Peptides and Proteins Using Bifunctional NHS-Activated Acrylamides". Angewandte Chemie International Edition (2021): http://dx.doi.org/10.1002/anie.202016936.
    Publicado • 10.1002/anie.202016936
  2. Celso Martins; Diego O. Hartmann; Adélia Varela; Jaime A. S. Coelho; Pedro Lamosa; Carlos A. M. Afonso; Cristina Silva Pereira. "Securing a furan-based biorefinery: disclosing the genetic basis of the degradation of hydroxymethylfurfural and its derivatives in the model fungus Aspergillus nidulans". Microbial Biotechnology (2020): https://doi.org/10.1111/1751-7915.13649.
    10.1111/1751-7915.13649
  3. Ravasco, Joao M. J. M.+; Coelho, Jaime A. S.+*. "Predictive Multivariate Models for Bioorthogonal Inverse-Electron Demand Diels-Alder Reactions". Journal of the American Chemical Society (2020): http://dx.doi.org/10.1021/jacs.9b11948.
    Publicado • 10.1021/jacs.9b11948
  4. Ravasco, João M. J. M.; Coelho, Jaime A. S.; Trindade, Alexandre F.; Afonso, Carlos A. M.. "Synthesis and reactivity/stability study of double-functionalizable strained trans-cyclooctenes for tetrazine bioorthogonal reactions". Pure and Applied Chemistry 92 1 (2020): 15-23. http://dx.doi.org/10.1515/pac-2019-0201.
    Publicado • 10.1515/pac-2019-0201
  5. Huang, Banruo; He, Ying; Levin, Mark D.; Coelho, Jaime A. S.; Bergman, Robert G.; Toste, F. Dean. "Enantioselective Kinetic Resolution/Desymmetrization of para-Quinols: A Case Study in Boronic-Acid-Directed Phosphoric Acid Catalysis". Advanced Synthesis & Catalysis 362 2 (2019): 295-301. http://dx.doi.org/10.1002/adsc.201900816.
    Publicado • 10.1002/adsc.201900816
  6. Marco Hebel; Andreas Riegger; Maksymilian M. Zegota; Gönül Kizilsavas; Jasmina Gacanin; Michaela Pieszka; Thorsten Lückerath; et al. "Sequence Programming with Dynamic Boronic Acid/Catechol Binary Codes". Journal of the American Chemical Society (2019): https://doi.org/10.1021/jacs.9b03107.
    10.1021/jacs.9b03107
  7. Martins, Inês S.; Coelho, Jaime A. S.*. "Solvent-Free Synthesis of 2,5Bis((dimethylamino)methylene)cyclopentanone". Methods and Protocols 2 3 (2019): 69. http://dx.doi.org/10.3390/mps2030069.
    Publicado • 10.3390/mps2030069
  8. Poeira, Diogo L.; Macara, João; Faustino, Hélio; Coelho, Jaime A. S.; Gois, Pedro M. P.; Marques, M. Manuel B.. "Hypervalent Iodine Mediated Sulfonamide Synthesis". European Journal of Organic Chemistry 2019 15 (2019): 2695-2701. http://dx.doi.org/10.1002/ejoc.201900259.
    Publicado • 10.1002/ejoc.201900259
  9. Rafael F. A. Gomes+; Jaime A. S. Coelho*+; Carlos A. M. Afonso*. "Direct Conversion of Activated 5-Hydroxymethylfurfural into d-Lactone-Fused Cyclopentenones". ChemSusChem 12 2 (2019): 420-425. https://doi.org/10.1002/cssc.201802537.
    Publicado • 10.1002/cssc.201802537
  10. Gomes, Rafael F. A.; Coelho, Jaime A. S.*; Afonso, Carlos A. M.*. "Synthesis and Applications of Stenhouse Salts and Derivatives". Chemistry - A European Journal 24 37 (2018): 9170-9186. http://dx.doi.org/10.1002/chem.201705851.
    Publicado • 10.1002/chem.201705851
  11. Zhu, Yi; Han, Jianlin; Wang, Jiandong; Shibata, Norio; Sodeoka, Mikiko; Soloshonok, Vadim A.; Coelho, Jaime A. S.; Toste, F. Dean. "Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs". Chemical Reviews 118 7 (2018): 3887-3964. http://dx.doi.org/10.1021/acs.chemrev.7b00778.
    Publicado • 10.1021/acs.chemrev.7b00778
  12. Gomes, Rafael F. A.; Nuno R. Esteves; Jaime A. S. Coelho*; Carlos A. M. Afonso*. "Copper(II) Triflate As a Reusable Catalyst for the Synthesis of trans-4,5-Diamino-cyclopent-2-enones in Water". The Journal of Organic Chemistry 83 14 (2018): 7509-7513. http://dx.doi.org/10.1021/acs.joc.7b02931.
    Publicado • 10.1021/acs.joc.7b02931
  13. Coelho, Jaime A. S.; Matsumoto, Akira; Orlandi, Manuel; Hilton, Margaret J.; Sigman, Matthew S.; Toste, F. Dean. "Enantioselective fluorination of homoallylic alcohols enabled by the tuning of non-covalent interactions". Chemical Science 9 35 (2018): 7153-7158. http://dx.doi.org/10.1039/c8sc02223b.
    Publicado • 10.1039/c8sc02223b
  14. Cavaca, L.A.S.; Rodrigues, C.A.B.; Simeonov, S.P.; Gomes, R.F.A.; Coelho, J.A.S.; Romanelli, G.P.; Sathicq, A.G.; Martínez, J.J.; Afonso, C.A.M.. "Valorization of Oleuropein via Tunable Acid-Promoted Methanolysis". ChemSusChem 11 14 (2018): 2300-2305. http://www.scopus.com/inward/record.url?eid=2-s2.0-85050403119&partnerID=MN8TOARS.
    10.1002/cssc.201800980
  15. Vicente, Ana; Coelho, Jaime A. S.; Simeonov, Svilen; Lazarova, Hristina; Popova, Margarita; Afonso, Carlos. "Oxidation of 5-Chloromethylfurfural (CMF) to 2,5-Diformylfuran (DFF)". Molecules 22 2 (2017): 329. http://dx.doi.org/10.3390/molecules22020329.
    Publicado • 10.3390/molecules22020329
  16. Joao M. J. M. Ravasco; Jaime A. S. Coelho; Svilen P. Simeonov; Carlos A. M. Afonso. "Bifunctional Cr3+ modified ion exchange resins as efficient reusable catalysts for the production and isolation of 5-hydroxymethylfurfural from glucose". RSC Advances 7 13 (2017): 7555-7559. https://doi.org/10.1039/C6RA22539J.
    Publicado • 10.1039/C6RA22539J
  17. Orlandi, M.; Coelho, J.A.S.; Hilton, M.J.; Toste, F.D.; Sigman, M.S.. "Parametrization of Non-covalent Interactions for Transition State Interrogation Applied to Asymmetric Catalysis". Journal of the American Chemical Society 139 20 (2017): 6803-6806. http://www.scopus.com/inward/record.url?eid=2-s2.0-85019657053&partnerID=MN8TOARS.
    10.1021/jacs.7b02311
  18. Simeonov, Svilen; Coelho, Jaime A. S.; Afonso, Carlos A. M.. "Synthesis of 5-(Hydroxymethyl)furfural (HMF)". Organic Syntheses 93 (2016): 29-36. http://dx.doi.org/10.15227/orgsyn.093.0029.
    Publicado • 10.15227/orgsyn.093.0029
  19. Ventura, Sónia P. M.; de Morais, Paulo; Coelho, Jaime A. S.; Sintra, Tânia; Coutinho, João A. P.; Afonso, Carlos A. M.. "Evaluating the toxicity of biomass derived platform chemicals". Green Chemistry 18 17 (2016): 4733-4742. http://dx.doi.org/10.1039/c6gc01211f.
    Publicado • 10.1039/c6gc01211f
  20. Gomes, Rafael F. A.; Coelho, Jaime A. S.*; Frade, Raquel F. M.; Trindade, Alexandre F.; Afonso, Carlos A. M.*. "Synthesis of Symmetric Bis(N-alkylaniline)triarylmethanes via Friedel–Crafts-Catalyzed Reaction between Secondary Anilines and Aldehydes". The Journal of Organic Chemistry 80 20 (2015): 10404-10411. http://dx.doi.org/10.1021/acs.joc.5b01875.
    Publicado • 10.1021/acs.joc.5b01875
  21. António, João P. M.; Frade, Raquel F. M.; Santos, Fábio M. F.; Coelho, Jaime A. S.; Afonso, Carlos A. M.; Gois, Pedro M. P.; Trindade, Alexandre F.. "NHC catalysed direct addition of HMF to diazo compounds: synthesis of acyl hydrazones with antitumor activity". RSC Adv. 4 55 (2014): 29352-29356. http://dx.doi.org/10.1039/c4ra03710c.
    Publicado • 10.1039/c4ra03710c
  22. Coelho, Jaime A. S.; Trindade, Alexandre F.; André, Vânia; Teresa Duarte, M.; Veiros, Luis F.; Afonso, Carlos A. M.. "Trienamines derived from 5-substituted furfurals: remote e-functionalization of 2,4-dienals". Org. Biomol. Chem. 12 46 (2014): 9324-9328. http://dx.doi.org/10.1039/c4ob01759e.
    Publicado • 10.1039/c4ob01759e
  23. Frade, R. F. M.; Coelho, J. A. S.; Simeonov, S. P.; Afonso, C. A. M.. "An emerging platform from renewable resources: selection guidelines for human exposure of furfural-related compounds". Toxicol. Res. 3 5 (2014): 311-314. http://dx.doi.org/10.1039/c4tx00019f.
    Publicado • 10.1039/c4tx00019f
  24. Coelho, Jaime A. S.; Trindade, Alexandre F.; Wanke, Riccardo; Rocha, Bruno G. M.; Veiros, Luis F.; Gois, Pedro M. P.; Pombeiro, Armando J. L.; Afonso, Carlos A. M.. "N-Heterocyclic Carbene Dirhodium(II) Complexes as Catalysts for Allylic and Benzylic Oxidations". European Journal of Organic Chemistry 2013 8 (2013): 1471-1478. http://dx.doi.org/10.1002/ejoc.201201300.
    Publicado • 10.1002/ejoc.201201300
  25. Simeonov, S.P.; Coelho, J.A.S.; Afonso, C.A.M.. "Integrated chemo-enzymatic production of 5-hydroxymethylfurfural from glucose". ChemSusChem 6 6 (2013): 997-1000. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878622602&partnerID=MN8TOARS.
    10.1002/cssc.201300176
  26. Trindade, Alexandre F.; Coelho, Jaime A. S.; Afonso, Carlos A. M.; Veiros, Luis F.; Gois, Pedro M. P.. "Fine Tuning of Dirhodium(II) Complexes: Exploring the Axial Modification". ACS Catalysis 2 3 (2012): 370-383. http://dx.doi.org/10.1021/cs200597a.
    Publicado • 10.1021/cs200597a
  27. Simeonov, S.P.; Coelho, J.A.S.; Afonso, C.A.M.. "An integrated approach for the production and isolation of 5-hydroxymethylfurfural from carbohydrates". ChemSusChem 5 8 (2012): 1388-1391. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864699780&partnerID=MN8TOARS.
    10.1002/cssc.201200236
  28. Kirillov, Alexander M.; Coelho, Jaime A. S.; Kirillova, Marina V.; Nesterov, Dmytro S.; Gruenwald, Katrin R.; Haukka, Matti; Pombeiro, Armando J. L.. "Bringing an “Old” Biological Buffer to Coordination Chemistry: New 1D and 3D Coordination Polymers with [Cu4(Hbes)4] Cores for Mild Hydrocarboxylation of Alkanes". Inorganic Chemistry 49 14 (2010): 6390-6392. http://dx.doi.org/10.1021/ic1007999.
    Publicado • 10.1021/ic1007999
Artigo em revista (magazine)
  1. Jaime A. S. Coelho; Rafael F. A. Gomes; Nuno R. Esteves; Svilen P. Simeonov; Carlos A. M. Afonso. "Criando Diversidade Estrutural a Partir de Biomassa: de Furanos a Ciclopentenonas Complexas", Boletim da Sociedade Portuguesa de Química (SPQ), 2020, https://www.spq.pt/magazines/BSPQuimica/692/article/30002278/pdf.
  2. Alexandre F. Trindade; Jaime A. S. Coelho; Rafael F. A. Gomes; João P. M. António; Carlos A. M. Afonso. "5-Hidroximetilfurfural: plataforma para obtenção de diversidade molecular", Boletim da SPQ, 2019, https://www.spq.pt/magazines/BSPQuimica/686/article/30002169/pdf.
Capítulo de livro
  1. Jaime A. S. Coelho; Carlos A. M. Afonso. "Preparation of 4,5-functionalized cyclopentenone via cyclization of Stenhouse adduct". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, editado por Carlos A. M. Afonso; Nuno R. Candeias; Dulce P. Simão; Alexandre F. Trindade; Jaime A. S. Coelho; Bin Tan; Robert Franzén. Reino Unido: Royal Society of Chemistry, 2016.
  2. Jaime A. S. Coelho; Carlos A. M. Afonso. "Regioselective catalytic transfer hydrogenation of citral". In Comprehensive Organic Chemistry Experiments for the Laboratory Classroom, editado por Carlos A. M. Afonso; Nuno R. Candeias; Dulce P. Simão; Alexandre F. Trindade; Jaime A. S. Coelho; Bin Tan; Robert Franzén. Reino Unido: Royal Society of Chemistry, 2016.
  3. Jaime A. S. Coelho; Filipe M. C. Menezes; Carlos A. M. Afonso. "Hidrogenação Catalítica e Regiosseletiva de Olefinas por Transferência de Hidrogénio". In 100 Experiências de Química Orgânica, editado por Carlos A. M. Afonso; Dulce P. Simão; Luísa P. Ferreira; Maria E. S. Serra; Maria M. M. Raposo. Lisbon, Portugal: IST Press, 2011.
Livro
  1. Various Authors. Comprehensive Organic Chemistry Experiments for the Laboratory Classroom. Reino Unido: Royal Society of Chemistry. 2016.
Tese / Dissertação
  1. Coelho, Jaime Alfredo da Silva, 1987-. "New synthetic methodologies for the transformation of biomass derived intermediates to valuable molecules". Doutoramento, Universidade de Lisboa Faculdade de Farmácia, 2014. http://hdl.handle.net/10451/15840.
  2. Coelho, Jaime. "Desenvolvimento de Novas Metodologias Sintéticas para a Transformação de Recursos Naturais Portugueses". Mestrado, Universidade de Lisboa Instituto Superior Técnico, 2010. https://fenix.tecnico.ulisboa.pt/cursos/mq/dissertacao/2353642285434.