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Identificação

Identificação pessoal

Nome completo
Nuno Jorge Ramos Abreu da Silva Lamas

Nomes de citação

  • Nuno Jorge Lamas

Identificadores de autor

Ciência ID
EC14-1A2D-C542
ORCID iD
0000-0002-4648-136X

Endereços de correio eletrónico

  • nunojlamas@med.uminho.pt (Profissional)

Moradas

  • Escola de Medicina/Instituto de Investigação em Ciências da Vida e Saúde (ICVS) da Universidade do Minho. Universidade do Minho, Campus de Gualtar, 4710-057 , Braga, Braga, Portugal (Profissional)

Websites

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Espanhol; Castelhano Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Francês Utilizador elementar (A1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador elementar (A1)
Alemão Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2015
Concluído
 Doutoramento em Medicina (Doutoramento)
Universidade do Minho Escola de Medicina, Portugal
"Harnessing the potential of pluripotent stem cells to develop novel platforms to study human motor neurons in vitro" (TESE/DISSERTAÇÃO)
 Bom com Distinção
2012
Concluído
 MEDICINE (Mestrado)
Universidade do Minho Escola de Medicina, Portugal
"A novel human pluripotent stem cell (hPSC)-derived astrocyte-motor neuron in vitro co-culture system to study human astroglial-motor neuron interactions" (TESE/DISSERTAÇÃO)
 16
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
2015/11/01 - Atual Professor Auxiliar Convidado (Docente Universitário) Universidade do Minho Escola de Medicina, Portugal
Universidade do Minho Escola de Medicina, Portugal
2012/10/01 - 2015/10/31 Assistente Convidado (Docente Universitário) Universidade do Minho Escola de Medicina, Portugal
Universidade do Minho Escola de Medicina, Portugal

Outras Carreiras

Categoria Profissional
Instituição de acolhimento 		Empregador
2022/03/25 - Atual Assistente (Médica) Centro Hospitalar Universitário do Porto EPE, Portugal
2018/04/01 - 2022/03/24 Interno (Médica) Centro Hospitalar Universitário do Porto EPE, Portugal
Centro Hospitalar Universitário do Porto EPE, Portugal
2016/07/01 - 2018/03/31 Interno (Médica) Hospital de Braga, Portugal
Hospital de Braga, Portugal
2014/01/01 - 2016/06/30 Interno (Médica) Hospital da Senhora da Oliveira Guimarães, Portugal
Hospital da Senhora da Oliveira Guimarães, Portugal
2013/01/01 - 2013/12/31 Interno (Médica) Hospital da Senhora da Oliveira Guimarães, Portugal
Hospital da Senhora da Oliveira Guimarães, Portugal
Projetos

Projeto

Designação Financiadores
2019/08/01 - Atual AAV-mediated delivery of FGF as a therapeutic strategy for amyotrophic lateral sclerosis
AFM22348
Investigador
Universidade do Minho Instituto de Investigação em Ciências da Vida e Saúde, Portugal
 AFM-Téléthon
Em curso
Produções

Publicações

Artigo em revista
  1. Carla Azevedo; Gabriel Teku; Yuriy Pomeshchik; Juan F. Reyes; Margarita Chumarina; Kaspar Russ; Ekaterina Savchenko; et al. "Parkinson’s disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein–induced changes in maturation and immune reactive properties". Proceedings of the National Academy of Sciences 119 12 (2022): https://doi.org/10.1073/pnas.2111405119.
    10.1073/pnas.2111405119
  2. Nuno Jorge Lamas; Ana Patrícia Rodrigues; Maria Araújo; José Ramón Vizcaíno; André Coelho. "Basaloid Follicular Hamartoma of the Eyelid: A Case Report and Literature Review about an Unusual Lesion in the Ocular Region". Diagnostics (2022): https://doi.org/10.3390/diagnostics12010140.
    10.3390/diagnostics12010140
  3. Nuno Jorge Lamas; Arnaud MARTEL; Sacha NAHON-ESTEVE; Samantha Goffinet; Adam Macocco; Corine Bertolotto; Sandra Lassalle; Paul Hofman. "Prognostic Biomarkers in Uveal Melanoma: The Status Quo, Recent Advances and Future Directions". Cancers (2021): https://www.mdpi.com/2072-6694/14/1/96.
    10.3390/cancers14010096
  4. "Harnessing the Potential of Human Pluripotent Stem Cell-Derived Motor Neurons for Drug Discovery in Amyotrophic Lateral Sclerosis: From the Clinic to the Laboratory and Back to the Patient". Frontiers in Drug Discovery 1 (2021): http://dx.doi.org/10.3389/fddsv.2021.773424.
    10.3389/fddsv.2021.773424
  5. Nuno Jorge Lamas. "Immunoglobulin G4 Related-Disease: A Rare Presentation With Secondary Hypereosinophilic Syndrome and Eosinophilic Ascites". Journal of Medical Cases 12 3 (2021): 107-111. http://dx.doi.org/10.14740/jmc3634.
    10.14740/jmc3634
  6. Nuno Jorge Lamas. "A rare cecal subepithelial tumor in a Crohn´s Disease patient". Autopsy Case Reports 11 (2020): http://dx.doi.org/10.4322/acr.2020.211.
    10.4322/acr.2020.211
  7. Nuno Jorge Lamas. "Nociceptive, emotional, electrophysiological, and histological characterization of the chronic constriction injury model in female Wistar Han rats.". Brain research bulletin (2020): https://doi.org/10.1016/j.brainresbull.2020.11.018.
    10.1016/j.brainresbull.2020.11.018
  8. Nuno Jorge Lamas; Francisca Emanuel Costa; José Ramón Vizcaíno. "Liquid-based cytology specimen preparation in the era of the COVID-19 pandemic: The experience of a laboratory in a portuguese central hospital". Cancer Cytopathology (2020): https://doi.org/10.1002/cncy.22358.
    10.1002/cncy.22358
  9. Nuno Jorge Lamas. "The Anatomic Pathology laboratory adjustments in the era of COVID-19 pandemic: The experience of a laboratory in a Portuguese central hospital". Annals of Diagnostic Pathology 48 (2020): 151560-151560. http://dx.doi.org/10.1016/j.anndiagpath.2020.151560.
    10.1016/j.anndiagpath.2020.151560
  10. Lamas, Nuno. "Parkinson's Disease and Fabry Disease: Clinical, Biochemical and Neuroimaging Analysis of Three Pedigrees.". Journal of Parkinson's disease (2020): https://europepmc.org/articles/PMC7029331.
    10.3233/jpd-191704
  11. Lamas, Nuno; Vieira E Monteiro, Eunice; Gaspar, Joana; Paiva, Cláudia; Correia, Raquel; Valente, Vítor; Coelho, André; Lamas, Nuno Jorge. "Abdominal Actinomycosis misdiagnosed as liposarcoma.". Autopsy & case reports (2019): https://europepmc.org/articles/PMC6945302.
    10.4322/acr.2020.137
  12. Savchenko, Ekaterina; Teku, Gabriel N.; Boza-Serrano, Antonio; Russ, Kaspar; Berns, Manon; Deierborg, Tomas; Lamas, Nuno Jorge; et al. "FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes". Scientific reports (2019): http://hdl.handle.net/1822/62378.
    10.1038/s41598-019-46110-1
  13. Marote, A.; Pomeshchik, Y.; Goldwurm, S.; Collin, A.; Lamas, N.J.; Pinto, L.; Salgado, A.J.; et al. "Generation of an integration-free induced pluripotent stem cell line (CSC-43J) from a patient with sporadic Parkinson's disease". Stem Cell Research 27 (2018): 82-85. http://www.scopus.com/inward/record.url?eid=2-s2.0-85040374677&partnerID=MN8TOARS.
    10.1016/j.scr.2018.01.007
  14. Li, Hai; Kuwajima,Takaaki; Oakley, Derek; Nikulina, Elena; Hou, Jianwei; Yang, Wan Seok; Lowry, Emily Rhodes; et al. "Protein Prenylation Constitutes an Endogenous Brake on Axonal Growth". Cell Reports (2016): http://hdl.handle.net/1822/50999.
    10.1016/j.celrep.2016.06.013
  15. Lamas, Nuno Jorge; Amorim, João Filipe Pinheiro; Almeida, António Manuel Melo Soares; Mendes, Sofia Silva; Martins, Sandra; Teixeira, Pedro Alexandre Leão Araújo Gonçalves; Oliveira, Tiago Gil; et al. "Ensino da Anatomia na Escola de Ciências da Saúde da Universidade do Minho". (2016): http://hdl.handle.net/1822/50986.
  16. Lamas, N.J.; Johnson-Kerner, B.; Roybon, L.; Kim, Y.A.; Garcia-Diaz, A.; Wichterle, H.. "Correction: Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures". PLoS ONE 10 3 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84925428109&partnerID=MN8TOARS.
    10.1371/journal.pone.0119195
  17. Lamas, Nuno Jorge; Serra, Sofia Cristina; Salgado, A. J.; Sousa, Nuno; Lamas NJ; Serra SC; Salgado AJ; Sousa N. "Failure of Y-27632 to improve the culture of adult human adipose-derived stem cells". (2015): http://hdl.handle.net/1822/34241.
    10.2147/SCCAA.S66597
  18. Lamas NJ; Johnson-Kerner B; Roybon L; Kim YA; Garcia-Diaz A; Wichterle H; Henderson CE; et al. "Neurotrophic requirements of human motor neurons defined using amplified and purified stem cell-derived cultures.". (2014): http://europepmc.org/abstract/med/25337699.
    10.1371/journal.pone.0110324
  19. Roybon L; Lamas NJ; Garcia-Diaz A; Yang EJ; Sattler R; Jackson-Lewis V; Kim YA; et al. "Human stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypes.". (2013): http://europepmc.org/abstract/med/23994478.
    10.1016/j.celrep.2013.06.021
  20. Lima-Rodrigues M; Lamas N; Valle-Fernandes A; Cruz A; Vieira A; Oliveira P; Pedrosa J; et al. "The selective COX-2 inhibitor Etoricoxib reduces acute inflammatory markers in a model of neurogenic laryngitis but loses its efficacy with prolonged treatment.". (2010): http://europepmc.org/abstract/med/20349107.
    10.1007/s00011-010-0185-5
  21. Rodrigues, Manuel Lima; Fernandes, Ana Valle; Lamas, Nuno Jorge; Cruz, Andrea; Baltazar, Fátima; Milanezi, Fernanda; Nunes, Rui; et al. "A new model of laryngitis: neuropeptide, cyclooxygenase, and cytokine profile". (2008): http://hdl.handle.net/1822/7897.
    10.1097/MLG.0b013e3181492400
Tese / Dissertação
  1. Lamas, Nuno Jorge. "Harnessing the potential of pluripotent stem cells to develop novel platforms to study human motor neurons in vitro". Doutoramento, 2015. http://hdl.handle.net/1822/37942.

Outros

Outra produção
  1. Generation of an induced pluripotent stem cell line (CSC-44) from a Parkinson's disease patient carrying a compound heterozygous mutation (c.823C>T and EX6 del) in the PARK2 gene. Mutations in the PARK2 gene, which encodes PARKIN, are the most frequent cause of autosomal recessive Parkinson's disease (PD). We report the generation of an induced pluripotent stem cell (iPSC) line from a 78-year-old patient carrying a compound heterozygous mutation (c.823C>T and EX6del) in the PARK2 gene. Skin fibroblasts were reprogrammed using the non-integrating Sendai virus technology to d. 2018. Marote, Ana; Pomeshchik, Yuriy; Goldwurm, Stefano; Collin, Anna; Lamas, Nuno Jorge; Pinto, Luísa; Salgado, A. J.; et al. http://hdl.handle.net/1822/57889.
    10.1016/j.scr.2018.01.006
Distinções

Outra distinção

2021 Giordano Fellowship 2022
European Society of Pathology (ESP), Bélgica
2007 Best Oral Presentation Prize in the section Neuroscience at II YES Meeting – Young European Scientist Meeting
2007 Best work of CibEMe 2007 Prize at CibEMe 2007 – Iberic Congress of Medical Students