Susana Isabel Sá is a neuroscientist with a PhD in Neurosciences and currently serves as Assistant Professor at the Faculty of Medicine of the University of Porto, where she has developed a sustained academic career combining teaching, research, and supervision. With a background in Biology and advanced training in morphology and neurosciences, her work has consistently focused on understanding how endogenous and exogenous factors modulate brain structure and function. Her scientific trajectory began with a strong foundation in neuroendocrinology, particularly in the study of estrogen-mediated synaptic plasticity in hypothalamic circuits. Over time, her research has evolved toward a broader and more translational perspective, addressing how pharmacological agents, drugs of abuse, and environmental exposures interfere with neuroplasticity, neurodevelopment, and behavior. A central theme of her work is the interaction between steroid hormones and the endocannabinoid system, and their combined impact on brain regions such as the hippocampus and hypothalamus, with implications for cognition, endocrine regulation, and sociosexual behavior. More recently, her research has expanded to include the study of prenatal and early-life exposures, particularly cannabis and environmental toxicants, and their consequences on neurodevelopmental outcomes. This line of work reflects an increasing integration of basic neuroscience with public health and clinical concerns, positioning her research within a translational and multidisciplinary framework. She is currently involved in national and collaborative research networks, contributing to projects that bridge laboratory findings with community health contexts. Methodologically, her work combines behavioral paradigms with quantitative neuroanatomy, immunohistochemistry, stereology, and molecular approaches, allowing for a comprehensive analysis of structural and functional brain changes. This integrative approach has supported a consistent and focused research line over time. She has authored over 40 peer-reviewed publications, including several as first or senior author, and has contributed to book chapters and international conferences. In parallel, she has supervised and co-supervised multiple PhD and Master’s students, fostering the development of new researchers in the fields of neuroscience, pharmacology, and toxicology. Alongside her research activity, she has maintained a strong commitment to teaching, with extensive experience in Human Anatomy and Neuroanatomy across multiple health-related degree programs, including Medicine, Nutrition Sciences, and Nursing. She has also been involved in curricular coordination and the development of advanced teaching modules, reflecting a sustained engagement in academic training and pedagogical innovation. Overall, her profile is characterized by a coherent and progressive research trajectory, sustained scientific productivity, and a balanced integration of teaching, supervision, and collaborative research, with a clear focus on the mechanisms underlying brain plasticity and their relevance for health and disease.