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Identificação

Identificação pessoal

Nome completo
Alessio Vagnoni

Nomes de citação

  • Vagnoni, Alessio

Identificadores de autor

Ciência ID
E617-3A6D-6D35
ORCID iD
0000-0003-2947-9193
Produções

Publicações

Artigo em revista
  1. Giamogante, Flavia; Barazzuol, Lucia; Maiorca, Francesca; Poggio, Elena; Esposito, Alessandra; Masato, Anna; Napolitano, Gennaro; et al. "A SPLICS reporter reveals alpha-synuclein regulation of lysosome-mitochondria contacts which affects TFEB nuclear translocation". Nature Communications 15 1 (2024): http://dx.doi.org/10.1038/s41467-024-46007-2.
    10.1038/s41467-024-46007-2
  2. Mattedi F; Lloyd-Morris E; Hirth F; Alessio Vagnoni. "Optogenetic cleavage of the Miro GTPase reveals the direct consequences of real-time loss of function in Drosophila.". PLoS biology (2023): https://europepmc.org/articles/PMC10465005.
    10.1371/journal.pbio.3002273
  3. Lucy Granat; Daniel Ranson; Debbra Knorr; Emma Hamer; Ram Prosad Chakrabarty; Francesca Mattedi; Laura Fort-Aznar; et al. "Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency". PLoS genetics 19 7 (2023): https://kclpure.kcl.ac.uk/portal/en/publications/e56f87c3-f1df-4c21-9777-93ff9290ee08.
    https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010793
  4. Francesca Mattedi; Daniel C Maddison; Gaynor Ann Smith; Alessio Vagnoni. "Live Imaging of Mitochondria in the Intact Fly Wing". Cold Spring Harbor protocols 2023 2 (2023): 106-112. https://kclpure.kcl.ac.uk/portal/en/publications/395cb895-70d8-4030-ae2d-2f0b6ffe1f36.
    10.1101/pdb.prot108052
  5. Victoria L. Hewitt; Leonor Miller-Fleming; Madeleine J. Twyning; Simonetta Andreazza; Francesca Mattedi; Julien Prudent; Franck Polleux; Alessio Vagnoni; Alexander J. Whitworth. "Decreasing pdzd8-mediated mito-ER contacts improves organismal fitness and mitigates Aß42 toxicity". Life Science Alliance 5 11 (2022): https://kclpure.kcl.ac.uk/portal/en/publications/061bca72-7653-4ca8-ab50-a29ca8a89ebd.
    10.26508/lsa.202201531
  6. Daniel C Maddison; Francesca Mattedi; Alessio Vagnoni; Gaynor Ann Smith. "Analysis of Mitochondrial Dynamics in Adult". Cold Spring Harbor protocols (2022): https://kclpure.kcl.ac.uk/portal/en/publications/d26c7c3c-0dbf-4381-839b-385325735fdb.
    10.1101/pdb.top107819
  7. Daniel C Maddison; Francesca Mattedi; Alessio Vagnoni; Gaynor Ann Smith. "Clonal Imaging of Mitochondria in the Dissected Fly Wing". Cold Spring Harbor protocols (2022): 10.1101/pdb.prot1080-10.1101/pdb.prot1080. https://kclpure.kcl.ac.uk/portal/en/publications/157d758a-dbfd-4627-a162-af43d8d565d3.
    10.1101/pdb.prot108051
  8. Alessio Vagnoni; Emily Annuario; Kristal Ng. "High-resolution imaging of mitochondria and mitochondrial nucleoids in differentiated SH-SY5Y cells". Methods in Molecular Biology (2022): https://kclpure.kcl.ac.uk/portal/en/publications/ca005c0e-a0f6-4d8f-b8f2-7285adf6311e.
    https://doi.org/10.1007/978-1-0716-1990-2_15
  9. Alessio Vagnoni; Francesca Mattedi; George Chennell. "Detailed imaging of mitochondrial transport and precise manipulation of mitochondrial function with genetically-encoded photosensitizers in adult Drosophila neurons". Methods in Molecular Biology (2022): https://kclpure.kcl.ac.uk/portal/en/publications/db7b9b0a-5a10-4850-ac42-b4581948757d.
    https://doi.org/10.1007/978-1-0716-1990-2_20
  10. Gábor M. Mórotz; Elizabeth Glennon; Jenny Greig; Dawn H.W. Lau; Nishita Bhembre; Francesca Mattedi; Nadine Muschalik; et al. "Kinesin light chain-1 serine-460 phosphorylation is altered in Alzheimer's disease and regulates axonal transport and processing of the amyloid precursor protein". Acta Neuropathologica Communications 7 1 (2019): https://kclpure.kcl.ac.uk/portal/en/publications/0c203dbd-a636-4d1d-8e1c-44d785dd0c1a.
    10.1186/s40478-019-0857-5
  11. Mórotz, G.M.; Glennon, E.B.; Gomez-Suaga, P.; Lau, D.H.W.; Robinson, E.D.; Sedlák, É.; Vagnoni, A.; Noble, W.; Miller, C.C.J.. "LMTK2 binds to kinesin light chains to mediate anterograde axonal transport of cdk5/p35 and LMTK2 levels are reduced in Alzheimer's disease brains". Acta neuropathologica communications 7 1 (2019): 73-73. http://www.scopus.com/inward/record.url?eid=2-s2.0-85065767031&partnerID=MN8TOARS.
    10.1186/s40478-019-0715-5
  12. Mattedi, F.; Vagnoni, A.. "Temporal Control of Axonal Transport: The Extreme Case of Organismal Ageing". Frontiers in Cellular Neuroscience 13 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85072726742&partnerID=MN8TOARS.
    10.3389/fncel.2019.00393
  13. Alessio Vagnoni; Simon L. Bullock. "A cAMP/PKA/Kinesin-1 Axis Promotes the Axonal Transport of Mitochondria in Aging Drosophila Neurons". Current Biology (2018): https://kclpure.kcl.ac.uk/portal/en/publications/8b022c26-5c06-4a9e-813a-3e0fd14bc5a3.
    10.1016/j.cub.2018.02.048
  14. James N. Sleigh; Alessio Vagnoni; Alison E. Twelvetrees; Giampietro Schiavo. "Methodological advances in imaging intravital axonal transport [version 1; referees: 3 approved]". (2017): https://f1000research.com/articles/6-200/v1.
    10.12688/f1000research.10433.1
  15. Vagnoni, A.; Bullock, S.L.. "A simple method for imaging axonal transport in aging neurons using the adult Drosophila wing". Nature Protocols 11 9 (2016): 1711-1723. http://www.scopus.com/inward/record.url?eid=2-s2.0-85015187726&partnerID=MN8TOARS.
    10.1038/nprot.2016.112
  16. Vagnoni, A.; Hoffmann, P.C.; Bullock, S.L.. "Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adult Drosophila neurons". Journal of Cell Science 129 1 (2016): 178-190. http://www.scopus.com/inward/record.url?eid=2-s2.0-84959017047&partnerID=MN8TOARS.
    10.1242/jcs.179184
  17. Vagnoni, A.; Glennon, E.B.C.; Perkinton, M.S.; Gray, E.H.; Noble, W.; Miller, C.C.J.. "Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aß production". Human Molecular Genetics 22 22 (2013): 4646-4652. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887005627&partnerID=MN8TOARS.
    10.1093/hmg/ddt313
  18. Vagnoni, A.; Perkinton, M.S.; Gray, E.H.; Francis, P.T.; Noble, W.; Miller, C.C.J.. "Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates aß production". Human Molecular Genetics 21 13 (2012): 2845-2854. http://www.scopus.com/inward/record.url?eid=2-s2.0-84863518335&partnerID=MN8TOARS.
    10.1093/hmg/dds109
  19. Manser, C.; Vagnoni, A.; Guillot, F.; Davies, J.; Miller, C.C.J.. "Cdk5/p35 phosphorylates lemur tyrosine kinase-2 to regulate protein phosphatase-1C phosphorylation and activity". Journal of Neurochemistry 121 3 (2012): 343-348. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859597153&partnerID=MN8TOARS.
    10.1111/j.1471-4159.2012.07650.x
  20. Mórotz, G.M.; De Vos, K.J.; Vagnoni, A.; Ackerley, S.; Shaw, C.E.; Miller, C.C.J.. "Amyotrophic lateral sclerosis-associated mutant VAPBP56s perturbs calcium homeostasis to disrupt axonal transport of mitochondria". Human Molecular Genetics 21 9 (2012): 1979-1988. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859246580&partnerID=MN8TOARS.
    10.1093/hmg/dds011
  21. Manser, C.; Guillot, F.; Vagnoni, A.; Davies, J.; Lau, K.-F.; McLoughlin, D.M.; De Vos, K.J.; Miller, C.C.J.. "Lemur tyrosine kinase-2 signalling regulates kinesin-1 light chain-2 phosphorylation and binding of Smad2 cargo". Oncogene 31 22 (2012): 2773-2782. http://www.scopus.com/inward/record.url?eid=2-s2.0-84859607330&partnerID=MN8TOARS.
    10.1038/onc.2011.437
  22. Vagnoni, A.; Rodriguez, L.; Manser, C.; De Vos, K.J.; Miller, C.C.. "Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1". Journal of Cell Science 124 7 (2011): 1032-1042. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953141458&partnerID=MN8TOARS.
    10.1242/jcs.075168
  23. Stevenson, A.; Yates, D.M.; Manser, C.; De Vos, K.J.; Vagnoni, A.; Leigh, P.N.; McLoughlin, D.M.; Miller, C.C.J.. "Riluzole protects against glutamate-induced slowing of neurofilament axonal transport". Neuroscience Letters 454 2 (2009): 161-164. http://www.scopus.com/inward/record.url?eid=2-s2.0-62949103631&partnerID=MN8TOARS.
    10.1016/j.neulet.2009.02.061
Pré-impressão
  1. James N. Sleigh; Francesca Mattedi; Sandy Richter; Kristal Ng; I. Emilie Steinmark; Iveta Ivanova; István L. Darabán; et al. "Age-specific and compartment-dependent changes in mitochondrial homeostasis and cytoplasmic viscosity in mouse peripheral neurons". 2023. http://dx.doi.org/10.1101/2023.09.18.558344.
    10.1101/2023.09.18.558344
  2. David Salvador-Garcia; Li Jin; Andrew Hensley; Mert Gölcük; Emmanuel Gallaud; Sami Chaaban; Fillip Port; et al. "A force-sensitive mutation reveals a spindle assembly checkpoint-independent role for dynein in anaphase progression". 2023. http://dx.doi.org/10.1101/2023.08.03.551815.
    10.1101/2023.08.03.551815
  3. "Detailed imaging of mitochondrial transport and precise manipulation of mitochondrial function with genetically-encoded photosensitizers in adult Drosophila neurons". 2021. http://dx.doi.org/10.21203/rs.3.rs-540726/v1.
    10.21203/rs.3.rs-540726/v1
  4. "High-resolution imaging of mitochondria and mitochondrial nucleoids in differentiated SH-SY5Y cells". 2021. http://dx.doi.org/10.21203/rs.3.rs-540708/v1.
    10.21203/rs.3.rs-540708/v1
  5. "Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy". 2020. http://dx.doi.org/10.1101/2020.11.14.382861.
    10.1101/2020.11.14.382861