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Carolina de Almeida Borlido. Completed a Master's Degree in Biochemistry, with specialization in Medical Biochemistry, in 2020 and an Undergraduate Degree in Biochemistry in 2018, both by Universidade de Lisboa Faculdade de Ciências. Currently is a Research Trainee at Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes. Published 2 articles in journals. Participated in 6 event(s). Works in the area(s) of Medical and Health Sciences with emphasis on Basic Medicine with emphasis on Neurosciences. Scientific interests include neurodegenerative diseases with emphasis on Alzheimer's disease, neuropharmacology, BDNF, Stem cells, blood and CSF biomarkers.
Identificação

Identificação pessoal

Nome completo
Carolina de Almeida Borlido

Nomes de citação

  • de Almeida-Borlido, Carolina

Identificadores de autor

Ciência ID
DA1B-1736-7CED
ORCID iD
0000-0001-8497-0917

Endereços de correio eletrónico

  • cborlido@medicina.ulisboa.pt (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português (Idioma materno)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Coreano Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1) Utilizador independente (B1)
Espanhol; Castelhano Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Alemão Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2) Utilizador elementar (A2)
Francês Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2022/09 - 2028
Em curso
Medicina (Mestrado integrado)
Universidade de Lisboa Faculdade de Medicina, Portugal
2021/09/07 - 2022/01/30
Em curso
Clinical Investigator Certificate (Pós-Graduação)
Especialização em CLIC Programme Level 1
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Universidade de Aveiro Associação para a Formação Profissional e Investigação, Portugal
2021/11 - 2021/12
Concluído
Introduction to Data Analysis (Outros)
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
2021/07
Concluído
Cambridge Advanced English (CAE) (Outros)
Cambridge Assessment, Reino Unido
C1 Level
2018/09 - 2020/10
Concluído
Biochemistry (Mestrado)
Especialização em Medical Biochemistry
Universidade de Lisboa Faculdade de Ciências, Portugal
"Searching for a new biomarker for Alzheimer's Disease based on BDNF receptor cleavage" (TESE/DISSERTAÇÃO)
17 (Master's Thesis: 19)
2020/02 - 2020/06
Concluído
Neuropharmacology (Outros)
Universidade de Lisboa Faculdade de Medicina, Portugal
17
2019/12
Concluído
Sejong Korean (Outros)
King Sejong Institute, Portugal
Level 3 certificate, Level 4 attendance
2014/09 - 2018/06
Concluído
Biochemistry (Licenciatura)
Universidade de Lisboa Faculdade de Ciências, Portugal
13
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2020/10 - Atual Investigador (Investigação) Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
2016/10 - 2018/09 Estagiário de Investigação (Investigação) Universidade de Lisboa Centro de Química e Bioquímica, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2019/09/02 - 2020/10/30 Research Master student Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
2020/05 - 2020/06 COVID-19 Diagnostic Task Force Volunteer Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
2018/02/01 - 2018/02/28 Volunteer Internship Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
Produções

Publicações

Artigo em revista
  1. Fonseca-Gomes, João; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Inteiro-Oliveira, Sara; Vaz, Sandra H.; Alemãn-Serrano, Nuno; Atalaia-Barbacena, Henrique; et al. "A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer’s disease". Molecular Therapy 33 1 (2025): 421. https://doi.org/10.1016/j.ymthe.2024.12.005.
    10.1016/j.ymthe.2024.12.005
  2. Fonseca-Gomes, João; Costa-Coelho, Tiago; Ferreira-Manso, Mafalda; Inteiro-Oliveira, Sara; Vaz, Sandra H.; Alemãn-Serrano, Nuno; Atalaia-Barbacena, Henrique; et al. "A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease". Molecular Therapy 32 10 (2024): 3372-3401. https://doi.org/10.1016/j.ymthe.2024.08.022.
    10.1016/j.ymthe.2024.08.022
  3. Catarina Miranda-Lourenço; Leonor Ribeiro-Rodrigues; João Fonseca-Gomes; Sara R. Tanqueiro; Rita F. Belo; Catarina B. Ferreira; Nádia Rei; et al. "Challenges of BDNF-based therapies: From common to rare diseases". Pharmacological Research (2020): 105281-105281. https://doi.org/10.1016/j.phrs.2020.105281.
    10.1016/j.phrs.2020.105281
  4. Belo, Rita F.; Martins, Margarida L. F.; Shvachiy, Liana; Costa-Coelho, Tiago; de Almeida-Borlido, Carolina; Fonseca-Gomes, João; Neves, Vera; et al. "The Neuroprotective Action of Amidated-Kyotorphin on Amyloid ß Peptide-Induced Alzheimer’s Disease Pathophysiology". Frontiers in Pharmacology 11 (2020): http://dx.doi.org/10.3389/fphar.2020.00985.
    Publicado • 10.3389/fphar.2020.00985
Poster em conferência
  1. de Almeida-Borlido, Carolina; Fonseca-Gomes, João; Ferreira, Catarina B.; Sebastião, Ana M.; de Mendonça, Alexandre; Diógenes, Maria José. "Searching for a potential novel biomarker for Alzheimer's disease based on BDNF receptor cleavage". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  2. Alemãn-Serrano, Nuno; Cardoso-Amaral, Rita; de Almeida-Borlido, Carolina; Costa-Coelho, Tiago; Miranda-Lourenço, Catarina ; Ribeiro-Rodrigues, Leonor; Sebastião, Ana M.; Diógenes, Maria José. "Method optimization to evaluate TrkB-ICD in Cerebrospinal Fluid and Blood of mice". Trabalho apresentado em XVII Meeting of the Portuguese Society for Neuroscience, 2021.
  3. Rita F. Belo; Margarida L. F. Martins; Liana Shvachiy; Tiago Costa-Coelho; Carolina de Almeida-Borlido; João Fonseca-Gomes; Vera Neves; et al. "Unveiling the molecular mechanism of amidated-kyotorphin: a neuroprotection action against Aß-induced Alzheimer's disease pathophysiology". Trabalho apresentado em SPF 2021, 2021.
  4. Carla Sousa; António de Granada Flor; Hugo A.L. Filipe; Clara Testard; Carolina Borlido; Diogo Vila Viçosa; Miguel Machuqueiro; Rodrigo F. M. de Almeida,. "Polyphenols intrinsic fluorescence as a versatile tool to quantify their interaction with membranes at different pH". Trabalho apresentado em X Iberian Spectroscopy Conference XXVI National Spectroscopy Meeting, 2018.
Tese / Dissertação
  1. de Almeida-Borlido, Carolina. "Searching for a new biomarker for Alzheimer's Disease based on BDNF receptor cleavage". Mestrado, Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, 2020.
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2021/09/20 BDNF receptor cleavage: A novel biomarker for Alzheimer’s disease Neuroscience Seminar
iMM/FMUL (Lisboa, Portugal)
2020/02 Searching for a new biomarker for Alzheimer’s Disease based on BDNF receptor cleavage 2º Encontro do Mestrado em Bioquímica
Faculdade de Ciências da Universidade de Lisboa (Lisboa, Portugal)
2019/10/30 Searching for a new biomarker for Alzheimer's Disease based on BDNF receptor cleavage Neuroscience Seminar
iMM/FMUL (Lisboa, Portugal)

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2021/12/01 - 2021/12/03 Meeting of professors, researchers, students and health professionals to discuss and present research work in the area of Neuroscience, with the intent to exhibit the scientific development in Portugal
Conferência
XVII Meeting of the Portuguese Society for Neuroscience
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2021/11/23 - 2021/11/24 Workshop organized by Professor Eleonora Aronica and Professor Erwin van Vliet (Amsterdam Medical Centre), which taught the different experimental models and tools to approach neurological diseases (in particular Epilepsy, but not exclusively)
Oficina (workshop)
Neuropathology of Epilepsy: from experimental models to human disease tissue
Amsterdam Universitair Medische Centra, Países Baixos
2021/10/13 - 2021/10/13 Seminar presented by Carolyn Finch (Clarivate Consultant), which invisioned to discuss established and emerging AD biomarkers and consider how systems biology approaches can provide a robust scientific rationale to support adoption of new biomarkers and accelerate approval of new drugs
Seminário
Why biomarkers are key to unlocking the promise of new disease modifying therapies for Alzheimer’s patients
Clarivate Analytics UK Limited, Reino Unido
2021/09/27 - 2021/10/01 Summer School that brought together scientists, clinical experts and early stage researchers in order to debate the state of art and current challenges in epilepsy(ies) treatment and research
Encontro
Trends and Challenges in epilepsy research
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
2021/02/17 - 2021/02/19 Research related to experimental pharmacology, clinical pharmacology and toxicology with the intent to exhibit the scientific development in Portugal
Conferência
SPF 2021
Sociedade Portuguesa de Farmacologia, Portugal

Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/02/16 - 2021/02/17 Symposium focused on Alzheimer's disease related to the current findings: mechanisms of this pathology, innovative techniques and emerging therapeutics
Simpósio
1st Symposium on Alzheimer's Disease: An Update on Pathology and Therapeutics
Universidade do Porto Faculdade de Engenharia, Portugal
2021/01/20 - 2021/01/20 Meeting to come across the main research lines in the participating institutions for epilepsy research (IMM, University of Lund, Amsterdam Medical Center University of Amsterdam and Sapienza University of Rome). It is also of interest for those with interests not closely related to epilepsy research since techniques anc concepts approaches used to understand several aspects of this pathology are common to those used in other research areas, such as neurodegeneration.
Encontro
Epileptogenesis and Epilepsy Network Kick-Off Meeting
Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal
2020/11/23 - 2020/11/23 Symposium focused on Organoids in developmental biology, disease modelling, regenerative medicine and drug screening. The sessions followed 3 topics: Mimicking development with stem cells and organoids; Organoids in disease I and II; Organ/tissue engineering and regenerative medicine
Simpósio
Organoids With]Out[ Borders
Universidade do Porto Instituto de Investigação e Inovação em Saúde, Portugal
2020/11/20 - 2020/11/20 Seminar with Jennifer Doudna PhD (University of California, Berkeley/HHMI), who was awarded the 2020 Nobel Prize in Chemistry with Emmanuelle Charpentier, PhD (a microbiologist at the Max Planck Institute in Berlin) due to the development of CRISPR-Cas9, a genome editing breakthrough that has revolutionized biomedicine. Doudna has embraced her leadership role, spearheading vital discussions about the ethics of hereditary genome editing, championing the value of basic academic research, and serving as an inspirational role model for women in science
Seminário
Women in Science: A Conversation with Jennifer Doudna, 2020 Nobel Laureate
Horizon Discovery Group plc, Reino Unido
2019/11/12 - 2019/11/13 Research related to Psychology, Neuroscience, Engineering and Language presented by students and professors from University of Lisbon
Encontro
5th meeting of the Mind-Brain college of the University of Lisbon and 17th meeting of Biomedical Engineering IST/FMUL
Universidade de Lisboa Faculdade de Medicina, Portugal
2018/01/26 - 2018/01/26 Meeting focused on clinical neuroscience. It followed the topics: Therapeutic options for depression and anxiety, Insomnia, Delirium, Deep brain stimulation and Ethical approach in patients with dementia. After the lectures, all attendees participated in a workshop related to neuroanatomy and clinical application.
Conferência
O cérebro e a mente - Neurociências para MGF
Universidade Nova de Lisboa Faculdade de Ciências Médicas, Portugal

Hospital CUF Descobertas, Portugal
2017/10/09 - 2017/10/11 Symposium focused on modern physiology in development, aging, immunity and cancer, bridging basic biology research with disease oriented research, and featured the winner of the 2002 Prize in Physiology or Medicine as a keynote lecture speaker
Simpósio
Champalimaud research symposium 2017 “Physiology from development to disease”
Fundação Champalimaud, Portugal

Entrevista (jornal / revista)

Descrição da atividade Jornal / Forum
2020 “À conversa com um aluno de bioquímica" Interview with 3 Biochemists who are volunteer members of the UNIAREA forum and provide help and guidance to students that desire to pursue Biochemistry and research UNIAREA

Membro de associação

Nome da associação Tipo de participação
2021/09 - Atual Portuguese Order of Biologists Effective Member

Tutoria

Tópico Nome do aluno
2020/10 - Atual Master Thesis (Integrated Master Degree in Medicine) Rita Amaral
2020/10 - Atual Master Thesis (Integrated Master Degree in Medicine) Nuno Ramalho
2020/10 - 2021/07 Master Thesis (Integrated Master Degree in Medicine) João Frederico Carvalho
Distinções

Prémio

2019 3rd place Quiz on Korea
King Sejong Institute, Portugal
2017 1st Place: Korean writing competition
King Sejong Institute, Portugal