Curriculum Vitae
Sónia Patrícia Dias Duarte
Identificação
Identificação pessoal
- Nome completo
- Sónia Patrícia Dias Duarte
Nomes de citação
- Duarte, S.P.
- Duarte S.
- Sónia P. Duarte
Identificadores de autor
- Ciência ID
- CD1E-CEC0-AFFC
Endereços de correio eletrónico
- sonia.duarte@cnc.uc.pt (Profissional)
Telefones
- Telefone
-
- 239820190 (Profissional)
Moradas
- Centro de Inovação em Biomedicina e Biotecnologia (CIBB)/Centro de Neurociências e Biologia Celular (CNC). Universidade de Coimbra, Rua Larga, Faculdade de Medicina Pólo I, 1º andar, 3004-504, Coimbra, Coimbra, Portugal (Profissional)
Websites
- https://cibb.uc.pt/research/innovative-therapies/vectors-gene-cell-therapy/ (Profissional)
- https://www.cnc.uc.pt/pt/people/s-duarte (Profissional)
- https://www.researchgate.net/profile/Sonia-Duarte-3 (Académico)
- https://www.linkedin.com/in/sonia-duarte-0760b219/ (Rede social)
Formação
| Grau | Classificação | |
|---|---|---|
|
2023/03/08 - 2023/03/08
Concluído
|
Webinar on Enabling and advancing mRNA-LNP medicines from concept to clinic (VACCINE INSIGHTS) (Outros)
Bioinsights Publishing, Reino Unido
|
|
|
2023/03/01 - 2023/03/01
Concluído
|
Webinar on Optimize your mRNA process from pDNA template to LNP encapsulation (CELL & GENE THERAPY INSIGHTS) (Outros)
Bioinsights Publishing, Reino Unido
|
|
|
2020/06/18 - 2020/06/18
Concluído
|
X-omics workshop: data standards and multi-omics data integration (Outros)
X-omics Organization, Países Baixos
|
|
|
2020/06/10 - 2020/06/10
Concluído
|
Workshop: "QIAGEN miRNA solutions" (Outros)
QIAGEN LLC, Estados Unidos
|
|
|
2019/06/12 - 2019/06/12
Concluído
|
Workshop: "Everything you need to know about miRNA qPCR" (Outros)
QIAGEN LLC, Estados Unidos
|
|
|
2013/02/01 - 2018/07/04
Concluído
|
Investigating the role of the Let-7 microRNA in Machado-Joseph disease (Pós-doutoramento)
Especialização em Neurosciences
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
N/A |
|
2015/07/16 - 2015/07/16
Concluído
|
Workshop: Bioestatística para trabalhos de investigação (Outros)
Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal
|
|
|
2015/02/05 - 2015/02/06
Concluído
|
Neuroepigenetics Advanced course of BEB PhD programme (Outros)
Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal
|
|
|
2014 - 2014
Concluído
|
Course in laboratory animal science- category B + Certificate of Researcher-coordinator for the practice of animal experimentation
(Outros)
Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal
Direcção-Geral de Alimentação e Veterinária, Portugal |
|
|
2013/01/15 - 2013/01/17
Concluído
|
Workshops at the Biogenesis and turnover of small RNAs meeting from Biochemical Society, Advancing Molecular Bioscience (Outros)
Biochemical Society, Reino Unido
Royal Society of Edinburgh, Reino Unido |
|
|
2008/03/01 - 2012/07/24
Concluído
|
PhD in Biochemistry (Doutoramento)
Especialização em Biochemical Technology
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"On the development of antitumoural therapeutic strategies: Suicide gene therapy mediated by lipid-based systems and cancer
stem cell-based vaccination" (TESE/DISSERTAÇÃO)
|
PhD with distinction and honors approved by unanim |
|
2009/10 - 2010/07
Concluído
|
Advanced Communication Skills in English I and II (Outros)
Universidade de Coimbra Faculdade de Letras, Portugal
|
|
|
2010/04 - 2010/06
Concluído
|
Curso de Formação Inicial de Formadores to acquire the CAP certificate (106 h) (Outros)
Tecla Center, Portugal
|
|
|
2010/03/04 - 2010/03/05
Concluído
|
Workshop: "RNA Therapeutics" (Outros)
Harvard Medical School, Estados Unidos
Fundação Calouste Gulbenkian, Portugal Instituto de Medicina Molecular João Lobo Antunes, Portugal |
|
|
2009/09/03 - 2009/09/04
Concluído
|
GTRV- Summer School « Targeted Drug Delivery » (Outros)
École Polytechnique Fédérale de Lausanne, Suiça
|
|
|
2005/02/22 - 2005/02/25
Concluído
|
Advanced Course on Gene Therapy (Outros)
Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal
|
|
|
2000/09 - 2004/07/23
Concluído
|
Biochemistry (Licenciatura)
Especialização em Biochemistry
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Validação de uma técnica de HPLC para determinação de anti-inflamatórios do grupo do Etofenamato" (TESE/DISSERTAÇÃO)
|
Final grade of 16 (out of 20). |
Percurso profissional
Ciência
| Categoria Profissional Instituição de acolhimento |
Empregador | |
|---|---|---|
| 2023/09/01 - Atual | Investigador Auxiliar (carreira) (Investigação) | Universidade de Coimbra, Portugal |
| Center for Neurosciences and Cell Biology, Portugal (...) |
||
| 2019/02/01 - 2023/08/31 | Investigador Contratado (Investigação) | Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal |
| Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal | ||
| 2018/07/05 - 2019/01/31 | Investigador Contratado (Investigação) | Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal |
| Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal | ||
| 2013/02/01 - 2018/07/04 | Pós-doutorado (Investigação) | Foundation for Science and Technology (Lisbon, Portugal) , Portugal |
| Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal | ||
| 2012/06/01 - 2012/12/31 | Pós-doutorado (Investigação) | Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal |
| Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal | ||
| 2008/03/01 - 2012/07/24 | Investigador (Investigação) | Foundation for Science and Technology (Lisbon, Portugal) , Portugal |
| Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal | ||
| 2011/05/01 - 2011/08/05 | Investigador visitante (Investigação) | Foundation for Science and Technology (Lisbon, Portugal) , Portugal |
| Centre National de la Recherche Scientifique (UMR 6235 CNRS), França | ||
| 2010/09/06 - 2010/12/20 | Investigador visitante (Investigação) | Foundation for Science and Technology (Lisbon, Portugal) , Portugal |
| Centre National de la Recherche Scientifique (UMR 6235 CNRS), França | ||
| 2007/06/01 - 2008/02/29 | Investigador (Investigação) | Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal |
| Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal | ||
| 2005/01/01 - 2007/05/31 | Investigador (Investigação) | Universidade do Minho, Portugal |
| Universidade do Minho, Portugal | ||
| 2003/09/01 - 2004/07/31 | Estagiário de Investigação (Investigação) | Laboratorios Basi S.A.-Industria Farmaceutica, Portugal |
| Laboratorios Basi S.A.-Industria Farmaceutica, Portugal |
Outros
| Categoria Profissional Instituição de acolhimento |
Empregador | |
|---|---|---|
| 2023/04/05 - 2023/09/01 | CAREER BREAK: Maternity Leave: Coimbra, Portugal | Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal |
| Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal | ||
| 2014/07/01 - 2015/01/01 | CAREER BREAK: Pregnancy/Maternity Leave: Coimbra, Portugal | Foundation for Science and Technology (Lisbon, Portugal) , Portugal |
| Center for Neurosciences and Cell Biology, Portugal |
Projetos
Bolsa
| Designação | Financiadores | |
|---|---|---|
| 2023/03/01 - Atual | Pre-clinical evaluation of the brain-targeting AAV-PHP.eB encoding cholesterol hydroxylase CYP46A1 as a therapeutic strategy
for spinocerebellar ataxia type 3 - towards the understanding of the neuroprotective mechanism
2022.04788.PTDC
Investigador
|
Fundação para a Ciência e a Tecnologia
Em curso
|
| 2023/01/01 - Atual | Direct Conversion of Astrocytes into Cerebellar Neurons as an Innovative Treatment for Spinocerebellar Ataxia Type-3
2022.06127.PTDC
Investigador
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
Fundação para a Ciência e a Tecnologia
Em curso
|
| 2021/09/16 - 2024 | "Repurposing FDA-approved Drugs as microRNA-specific modifiers towards a new and promising therapeutic approach for Machado-Joseph
disease/spinocerebellar ataxia type 3 (MJD/SCA3)"
Trampoline Grant 23755
Investigador responsável
Center for Neurosciences and Cell Biology, Portugal
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal |
AFM-Téléthon
Em curso
|
| 2021/09/01 - 2022/12/31 | MicroRNA-specific small molecule modifiers as a new and promising therapeutic approach for Machado-Joseph disease/spinocerebellar
ataxia type 3 (MJD/SCA3)
NAF Young Investigator Award
Investigador responsável
Center for Neurosciences and Cell Biology, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
National Ataxia Foundation
Em curso
|
| 2018/07/06 - 2022/04/05 | Role of microRNA deregulation in Machado-Joseph Disease: On the development of a microRNA-based therapeutic strategy
POCI-01-0145-FEDER-032309
Investigador responsável
Center for Neurosciences and Cell Biology, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Fundação para a Ciência e a Tecnologia Comissão de Coordenação e Desenvolvimento Regional do Centro Em curso
|
| 2020 - 2022/02/28 | Intravenous delivery of the brain-targeting AAV-PHPeB encoding the cholesterol hydroxylase CYP46A1 into a mouse model of spinocerebellar
ataxia type 3: a promising non-invasive therapeutic strategy
686213
Investigador
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
National Ataxia Foundation |
| 2019 - 2021/12 | Gene Therapy for Cerebellar Ataxias: restoring cholesterol metabolism by targeting brain cholesterol 24 hydroxylase (CYP46A1)
- SCA-CYP (International Consortium)
E-Rare-3 JTC 2017 (International Consortium)
Investigador
CNC.IBILI, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
|
| 2018/06 - 2021/06 | The impact of induced pluripotent stem cells-derived neuroepithelial stem cells transplantation in Machado-Joseph disease
POCI-01-0145-FEDER-030737
Investigador
Center for Neurosciences and Cell Biology, Portugal
|
Comissão de Coordenação e Desenvolvimento Regional do Centro Fundação para a Ciência e a Tecnologia Em curso
|
| 2017/01 - 2020/12 | BRAIN HEALTH 2020-Detecção Precoce,Neuro-modulação e TerapiasAvançadas para Neuropatologias
CENTRO-01-0145-FEDER-000008
Investigador
Center for Neurosciences and Cell Biology, Portugal
|
Centro2020 - Programa Operacional Centro 2020 (FEDER/FSE) Foundation for Science and Technology (Lisbon, Portugal) Em curso
|
| 2016/04 - 2020/05 | ModelPolyQ: Advanced models of polyglutamine disorders (HD, SCA3 and SCA7)
Investigador
Center for Neurosciences and Cell Biology, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
EU Joint Programme Neurodegenerative Disease Research |
| 2016 - 2020/05 | JPND European Spinocerebellar Ataxia Type 3/Machado-Joseph Disease Initiative
JPCOFUND/0001/2015-ESMI (International Consortium)
Investigador
Center for Neurosciences and Cell Biology, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
EU Joint Programme Neurodegenerative Disease Research
Em curso
|
| 2017/03/27 - 2020/03/26 | LifeSciences ByCENTRO
CENTRO-01-0246-FEDER-000011
Investigador
CNC.IBILI, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Centro2020 - Programa Operacional Centro 2020 (FEDER/FSE) |
| 2016/04 - 2019/03 | Gene repair and repression strategies to alleviate Machado-Joseph disease
PTDC/NEU-NMC/0084/2014
Investigador
Center for Neurosciences and Cell Biology, Portugal
|
Foundation for Science and Technology (Lisbon, Portugal)
Concluído
|
| 2015/03 - 2018/12 | Roles and mechanisms of synuclein and ataxin-3 spreading in Parkinson and Machado-Joseph diseases
JPND SynSpread: CD/0001/2013 (International consortium)
Investigador
Center for Neurosciences and Cell Biology, Portugal
|
EU Joint Programme Neurodegenerative Disease Research Foundation for Science and Technology (Lisbon, Portugal) Concluído
|
| 2013/02/01 - 2018/07/04 | Investigating the role of the Let-7 microRNA in Machado-Joseph disease
SFRH/BPD/87552/2012
Bolseiro de Pós-Doutoramento
Center for Neurosciences and Cell Biology, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluído
|
| 2013/03 - 2016/02 | Machado-Joseph-Disease, protein aggregation, protein degradation, stem cell biology, proteostasis, neurodegeneration
E-Rare4/0003/2012 (International consortium)
Investigador
Center for Neurosciences and Cell Biology, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluído
|
| 2013/03 - 2015/08 | Exploring miRNA contribution to amyloid-b-metabolism: development of a novel lentiviral platform for multiple miRNA expression
in Alzheimer´s disease
PTDC/BIM-MEC/0651/2012
Investigador
Center for Neurosciences and Cell Biology, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluído
|
| 2013/03 - 2015/06 | Combined therapeutic approach based on miRNA modulation towards glioblastoma multiforme: A novel targeted lipid-based nanosystem
for systemic delivery
PTDC/DTP-FTO/0265/2012
Investigador
Center for Neurosciences and Cell Biology, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluído
|
| 2012/06 - 2012/12 | Non-invasive Non-viral Silencing of Machado-Joseph disease
PTDC/SAU-FAR/116535/2010
Bolseiro de Investigação
Center for Neurosciences and Cell Biology, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluído
|
| 2008/03/01 - 2012/03/01 | ON THE DEVELOPMENT OF ANTITUMOURAL THERAPEUTIC STRATEGIES: Suicide gene therapy mediated by lipid-based systems and cancer
stem cell-based vaccination
SFRH/BD/32797/2007
Bolseiro de Doutoramento
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
Center for Neurosciences and Cell Biology, Portugal |
Fundação para a Ciência e a Tecnologia
Concluído
|
| 2007/06 - 2008/02 | Development of a novel approach for anti-tumor therapy based on the S413-PV cell penetrating peptide to improve the intracellular
delivery of therapeutic proteins and nucleic acids
PTDC/BIO/65627/2006
Bolseiro de Investigação
Center for Neurosciences and Cell Biology, Portugal
|
Fundação para a Ciência e a Tecnologia
Concluído
|
| 2005/01 - 2007/05 | Preparação de agentes para Terapia Molecular por purificação e condensação simultânea de plasmídeos em sistemas de duas fases
aquosas
POCTI BIO/47245/2002
Bolseiro de Investigação
Universidade do Minho, Portugal
|
Universidade do Minho
Concluído
|
Projeto
| Designação | Financiadores | |
|---|---|---|
| 2023/09/01 - Atual | CinTech - Technological Hub for Innovation, Translation and Industrialization of Complex Injectable Drugs
12345
Investigador
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
|
| 2020/07 - Atual | "miRSilencing" project
international collaborative project between the Center for Neuroscience and Cell Biology (CNC, UC, Portugal) and PTC Therapeutics
(USA)
Investigador
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal |
PTC Therapeutics Inc
Em curso
|
| 2018/05 - Atual | "Targeting mutant ATXN3 for the treatment of Spinocerebellar Ataxia 3 (SCA3) using allele-specific ASOs
International collaborative project between CNC and Wave Life Sciences USA, Inc
Investigador
Center for Neurosciences and Cell Biology, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Wave Life Sciences USA, Inc
Em curso
|
| 2021/01/01 - 2025/12/31 | Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
Investigador
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
Fundação para a Ciência e a Tecnologia
Em curso
|
| 2020/01/01 - 2023/12/31 | Center for Innovative Biomedicine and Biotechnology
UIDB/04539/2020
Investigador
|
Fundação para a Ciência e a Tecnologia
Em curso
|
| 2019/02 - 2019/10 | Targeting ATXN3 for the treatment of Spinocerebellar Ataxia 3 (SCA3) using AAV5 and an artificial microRNA
International Collaborative Project between CNC and uniQure Company
Investigador
Center for Neurosciences and Cell Biology, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
uniQure NV
Concluído
|
| 2015/01 - 2017/12 | “CNC. IBILI”
UID/NEU/04539/2013
Investigador
Center for Neurosciences and Cell Biology, Portugal
|
Foundation for Science and Technology (Lisbon, Portugal)
Concluído
|
Outro
| Designação | Financiadores | |
|---|---|---|
| 2022 - Atual | greenLabsCIBB (gLCIBB)
gLCIBB
Investigador
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
Em curso
|
| 2018/05/01 - Atual | Collaboration with Wave Life Sciences company, uniQure and Brainvectis in the development of a gene therapy product applied
to neurodegenerative disorders, particularly to polyglutamine disorders.
INTERNATIONAL NETWORKS
Investigador
Center for Neurosciences and Cell Biology, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Em curso
|
| 2018 - Atual | Lab management (organizing/ordering/managing the lab products, space/people in the lab)
LAB MANAGMENT
Outra
Center for Neurosciences and Cell Biology, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Em curso
|
| 2013 - Atual | Collaboration with La Spada AR, who first discovered polyglutamine disorders at the University of Duke
INTERNATIONAL NETWORK
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
Em curso
|
Produções
Publicações
| Artigo em jornal |
|
| Artigo em revista |
|
| Capítulo de livro |
|
| Poster em conferência |
|
| Resumo em conferência |
|
| Tese / Dissertação |
|
Artística / Interpretação
| Gravação vídeo |
|
| Guião |
|
Outros
| Outra produção |
|
Atividades
Apresentação oral de trabalho
| Título da apresentação | Nome do evento Anfitrião (Local do evento) |
|
|---|---|---|
| 2024/02/07 | Targeted silencing via AAV9 polycistronic microRNA therapy rescues SCA3 molecular, neuropathological and motor deficits | 54th Annual meeting of the Portuguese Pharmacology Society, Lisboa, 7-9 February 2024
NOVA Medical School
|
| 2024/02/07 | Mesenchymal Stromal Cell Therapeutic Potential to Restore Neurovascular Integrity in Spinocerebellar Ataxia Type 3 | 54th Meeting of the Portuguese Society of Pharmacology, Lisboa, 7-9 February 2024
NOVA Medical School
|
| 2022/10/28 | MicroRNAs at the cornerstone of Machado-Joseph Disease pathogenesis: Leveraging disease-associated miRNA dysregulation to develop microRNA-based therapeutics (by invitation) | 4th meeting of the CIBB thematic area ‘Innovative Therapies’
Anfiteatro Subunidade 3 | FMUC, Polo III (Coimbra, Portugal)
|
| 2022/06/01 | MicroRNA pathway dysfunction in Machado-Joseph disease: implications in pathology and development of a microRNA-based therapy (by Invitation) | DCV.Talks
Amphitheatre 1, S. Bento building, Polo 1, Coimbra, Portugal (Coimbra, Portugal)
|
| 2022/04/02 | Non-invasive delivery of the brain-targeting AAV-PHP.eB encoding the cholesterol hydroxylase CYP46A1 into a mouse model of spinocerebellar ataxia type 3: a promising therapeutic strategy | CONGRESSO SPDMOV (Sociedade Portuguesa das Doenças do Movimento) 2022, April 1, 2
Grande Hotel do Luso, Portugal (Luso, Portugal)
|
| 2022/02/21 | Induced Pluripotent Stem cells derived from Machado-Joseph Disease patients as a promising model to investigate microRNA dysregulation | 52ª reunião da Sociedade Portuguesa de Farmacologia - SPF 2022 (9-11 fevereiro 2022)
ICBAS, Porto, (Portugal)
|
| 2022/02/09 | Reverting dysregulation of microRNA levels as a promising therapeutic strategy for Machado-Joseph Disease | 52ª reunião da Sociedade Portuguesa de Farmacologia - SPF 2022 (9-11 fevereiro 2022)
ICBAS, Porto (Portugal)
|
| 2022/02/09 | Assessing the potential of mesenchymal stromal cells for alleviation of blood-brain barrier dysfunction in MachadoJoseph Disease | 52ª reunião da Sociedade Portuguesa de Farmacologia - SPF 2022 (9-11 fevereiro 2022)
ICBAS, Porto (Portugal)
|
| 2022/02/09 | Validation of the brain-targeting AAVPHPeB enconding cholesterol hydroxylase CYP46A1 as a therapeutic candidate for Spinocerebellar Ataxia Type-3 | 52ª reunião da Sociedade Portuguesa de Farmacologia - SPF 2022 (9-11 fevereiro 2022)
ICBAS, Porto (Portugal)
|
| 2021/04/21 | MiRNA dysregulation in Machado-Joseph Disease | Advanced Therapies in the Doctoral Programme in Experimental Biology and Biomedicine (PDBEB)
Center for Neurosciences and Cell Biology (Coimbra, Portugal) (Coimbra)
|
| 2021/02/19 | IPSC-derived neuroepithelial stem cells depleted for mutant ataxin-3 for Machado-Joseph disease treatment | 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia, February
17-19, 2021
Faculdade de Farmácia da Universidade de Lisboa. Virtual meeting (Portugal)
|
| 2021/02/19 | Phenotypic characterization of neuronal cultures derived from Machado-Joseph disease induced pluripotent stem cells | 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia, February
17-19, 2021
Faculdade de Farmácia da Universidade de Lisboa. Virtual meeting (Portugal)
|
| 2021/02/18 | Allele-specific silencing of Machado-Joseph disease using antisense oligonucleotide therapeutics | 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia, February
17-19, 2021
Faculdade de Farmácia da Universidade de Lisboa. Virtual meeting (Portugal)
|
| 2021/02/18 | Identification of dysregulated mirnas in human induced pluripotent stem cell-based models of Machado-Joseph disease: one step closer to a therapeutic approach? | 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia, February
17-19, 2021
Faculdade de Farmácia da Universidade de Lisboa. Virtual meeting (Portugal)
|
| 2021/02/18 | Unravelling dysregulated micrornas in a transgenic mouse model of Machado-Joseph disease | 51.ª Reunião da Sociedade Portuguesa de Farmacologia, 39.ª Reunião de Farmacologia Clínica e 20ª Reunião de Toxicologia, February
17-19, 2021
Faculdade de Farmácia da Universidade de Lisboa. Virtual meeting (Portugal)
|
| 2020/10/14 | Thinking Small: Towards microRNA-based therapeutics for Machado-Joseph disease (by Invitation) | Neuroscience and Disease Thematic Line Joint DataClub- a forum for discussion
Center for Innovative Biomedicine and Biotechnology (CIBB) (Portugal)
|
| 2020/03/03 | Autophagy-regulation mediated by microRNAs in Neurodegenerative Diseases (by invitation) | American Society for Experimental Neurotherapeutics 2020 (ASENT 2020)
American Society for Experimental Neurotherapeutics (Bethesda MD, Washington DC, Estados Unidos)
|
| 2020/02/05 | CRISPR-mediated silencing of mutant ataxin-3 ameliorates motor symptoms of a Machado-Joseph disease model in vivo | 50.ª Reunião da Sociedade Portuguesa de Farmacologia, 38.ª Reunião de Farmacologia Clínica e 19.ª Reunião de Toxicologia
Sociedade Portuguesa de Farmacologia (Coimbra , Portugal)
|
| 2020/02/05 | Human IPSC-derived neuroepithelial stem cells for cell-based therapy in Machad-Joseph disease, | 50.ª Reunião da Sociedade Portuguesa de Farmacologia, 38.ª Reunião de Farmacologia Clínica e 19.ª Reunião de Toxicologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
|
| 2019/12/19 | MSC Success in Promoting Ameliorations in Machado-Joseph Disease - Where do We Stand and Where We Should Go? (by invitation) | Center for Innovative Biomedicine and Biotechnology (CIBB) Meeting
Center for Innovative Biomedicine and Biotechnology (CIBB) (Coimbra, Portugal)
|
| 2019/11/15 | Extracellular vesicles-associated AAVs as gene delivery vectors for the treatment of brain disorders | 1st Annual Meeting in Pharmaceutical Sciences
Pharmaceutical Sciences (Coimbra, Portugal)
|
| 2019/11/15 | Human iPSC-derived neuroepithelial stem cells as a source for cell therapy in Machado-Joseph disease | 1st Annual Meeting in Pharmaceutical Sciences. November 15, 2019, Coimbra, Portugal
(Portugal)
|
| 2019/11/13 | "Mecanismos de doença - da alteração genética à disfunção celular e sua manifestação clínica (by invitation) | Curso Ataxias hereditárias e paraparésias espásticas: da biologia molecular ao tratamento, Pré - Congresso de Neurologia 2019,
November 13, 2019, Coimbra, Portugal
Sociedade Portuguesa de Neurologia (Coimbra, Portugal)
|
| 2019/10/10 | Spectroscopic Biomarkers as a Way of Monitoring MSC Success in Promoting Neuropathological and Phenotypic Ameliorations in Machado-Joseph Disease Models | 11th International Meeting of the Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC)
Portuguese Society for Stem Cells and Cell Therapies (SPCE-TC) (Lisbon, Portugal)
|
| 2019/05/30 | Autophagy activation induced by let-7 microrna overexpression counteracts disease phenotype in Machado-Joseph disease mouse models | XVI Meeting of the Portuguese Society for Neuroscience (SPN2019), May 30-June 1, 2019
Portuguese Society for Neuroscience (Lisbon, Portugal)
|
| 2019/05/30 | Human IPSC-derived neuroepithelial stem cells for cell-based therapies in Machado-Joseph disease | XVI Meeting of the Portuguese Society for Neuroscience (SPN2019), May 30-June 1, 2019
Portuguese Society for Neuroscience (Lisbon, Portugal)
|
| 2019/05/22 | CRISPR interference-mediated silencing of mutant ATXN3 decreases motor impairments of an in vivo Machado-Joseph disease model | 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), May 22-24, 2019
European Society for Clinical Investigation (ESCI) (Coimbra, Portugal)
|
| 2019/05/22 | Repeated transplantation of mesenchymal stromal cells in Machado-Joseph disease/Spinocerebellar ataxia type-3 mice can sus- tainably alleviate phenotypic symptoms and ameliorations can be monitored through magnetic resonance spectroscopy (by invitation) | 53rd Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI), May 22-24, 2019
European Society for Clinical Investigation (ESCI) (Coimbra, Portugal)
|
| 2019/05/10 | Cerebellar transplantation of human iPSC-derived neuroepithelial stem cells for Machado-Joseph disease treatment (by invitation) | Neuroscience and Diseases Retreat
Center for Innovative Biomedicine and Biotechnology (CIBB) (Miranda do corvo, Portugal)
|
| 2019/02/06 | Extracellular vesicles-associated AAVs as gene delivery vectors for the treatment of brain diseases | XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia Clínica e XVIII Reunião de Toxicologia,
February 6-8, 2019
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
|
| 2019/02/06 | Human IPSC-derived neuroepithelial stem cells for neuroprotection and neuroregeneration in Machado-Joseph disease | XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia Clínica e XVIII Reunião de Toxicologia,
February 6-8, 2019
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
|
| 2019/02/06 | Mutant ataxin-3 spreading in Machado-Joseph disease, | XLIX Reunião da Sociedade Portuguesa de Farmacologia, XXXVII Reunião de Farmacologia Clínica e XVIII Reunião de Toxicologia,
February 6-8, 2019
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
|
| 2019/01/17 | Doenças de expansão de poliglutaminas - Machado-Joseph a ataxia dominante mais comum (by invitation) | Conferências IEC and UNISOB
Universidade Sénior de Oliveira do Bairro (UNISOB), an initiative from Instituto de Educação e Cidadania (IEC) in collaboration
with UNISOB (Oliveira do Bairro, Portugal)
|
| 2018/10/09 | Patient-specific iPSC-derived neuroepithelial stem cells for neuroprotection and neuroregeneration in Machado-Joseph disease | 10th International Symposium on Neuroprotection and Neurorepair, October 9-11, 2018
Federation of European Neuroscience Societies (Dresden, Alemanha)
|
| 2018/03/02 | Let-7 microRNA-based therapy alleviates neuropathology, imbalance and motor incoordination in Machado-joseph disease | Congresso da SPDMov 2018 - Genética das Doenças do Movimento, March 2-3, 2018
Sociedade Portuguesa das Doenças do Movimento (SPDMov) (Curia, Portugal)
|
| 2018/03/02 | Repeated mesenchymal stromal cells treatment sustainably alleviates Machado-Joseph Disease/Spinocerebellar ataxia type-3 AND therapeutic success can be monitored by 1H-MRS | Congresso da SPDMov 2018 - Genética das Doenças do Movimento, March 2-3, 2018
Sociedade Portuguesa das Doenças do Movimento (SPDMov) (Curia, Portugal)
|
| 2018/02/05 | Let-7 mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease | XLVIII Reunião da Sociedade Portuguesa de Farmacologia, XXXVI Reunião de Farmacologia Clínica, e XVII Reunião de Toxicologia,
February 5-7, 2018
Sociedade Portuguesa de Farmacologia (SPF) (Lisbon, Portugal)
|
| 2018/02/05 | Microrna dysregulation in machado-joseph disease: from pathogenesis to therapy | XLVIII Reunião da Sociedade Portuguesa de Farmacologia, XXXVI Reunião de Farmacologia Clínica, e XVII Reunião de Toxicologia,
February 5-7, 2018
Sociedade Portuguesa de Farmacologia (SPF) (Lisbon, Portugal)
|
| 2018/02/05 | Repeated mesenchymal stromal cells treatment sustainably alleviates machado-joseph disease | XLVIII Reunião da Sociedade Portuguesa de Farmacologia, XXXVI Reunião de Farmacologia Clínica, e XVII Reunião de Toxicologia,
February 5-7, 2018
Sociedade Portuguesa de Farmacologia (Lisbon, Portugal)
|
| 2017/12/21 | Implications of microRNAs dysregulation in Machado-Joseph Disease: From pathogenesis to therapy (by Invitation) | 2ND Meeting on Biomedical Research @ UC, December 21st, 2017
(Coimbra, Portugal)
|
| 2017/10/12 | Human iPSCs-derived NESCs for cerebellar transplantation in Machado-Joseph disease | 10th International meeting of the Portuguese society for Stem cells and Cell Therapies, October 12-14, 2017
Portuguese society for Stem cells and Cell Therapies (Covilhã, Portugal)
|
| 2017/09/27 | Let-7 activates autophagy and alleviates motor and neuropathological deficits in pre- and post-symptomatic Machado-Joseph disease mouse models | International Ataxia Research Conference, September 27-30, 2017
Ataxia UK, GoFar (Italian organisation) and FARA (American organisation) (Pisa, Itália)
|
| 2011/12/19 | Efficient gene delivery and potent antitumoral activity in vitro and in vivo mediated by a new folate (FA)-associated lipoplex formulation | IX Annual Meeting - Center for Neurosciences and Cell Biology & Doctoral Programme in Biology and Experimental Biomedicine,
December 19-20, 2011
Center for Neurosciences and Cell Biology & Doctoral Programme in Biology and Experimental Biomedicine (coimbra, Portugal)
|
| 2009/12/21 | Non-covalent strategies combining cationic lipids and CPPs to enhance the delivery of nucleic acids – looking at cellular internalization and biological activity | VII Annual Meeting - Center for Neurosciences and Cell Biology & Doctoral Programme in Biology and Experimental Biomedicine,
December 21-22, 2009
Center for Neurosciences and Cell Biology & Doctoral Programme in Biology and Experimental Biomedicine (Cantanhede, Portugal)
|
| 2009/09/03 | Folate receptor-targeting delivery of lipid-based systems aiming at cancer gene therapy | GTRV- Summer School «Targeted Drug Delivery», September 3-4, 2009
(Lausanne, Suiça)
|
| 2009/08/31 | Optimization of S4(13)-PV cell penetrating peptide-based vectors for the delivery of nucleic acids – study of cellular internalization and biological activity | 3rd Intracellular Delivery of Therapeutic Molecules: From Bench to Bedside, August 31-September 2, 2009
(Montpellier, França)
|
| 2008/08/30 | S413-PV cell penetrating peptide associated with different cargos: assessment of delivery efficiency and internalization mechanisms | Cell-Penetrating Peptides Satellite Symposium of the 30th European Peptide Symposium, August 30-31, 2008
European Peptide Society (EPS) and the Finnish Peptide Society (FIPS) (Helsinki, Finlândia)
|
| 2006/08/27 | Simultaneous purification and condensation of plasmid DNA with PEGylated Polyethyleneimine in Aqueous Two-Phase Systems | 6th European Symposium on Biochemical Engineering Science (ESBES 6) | August 27 - 30, 2006
European Society of Biochemical Engineering Sciences (Salzburg, Áustria)
|
Orientação
| Título / Tema Papel desempenhado |
Curso (Tipo) Instituição / Organização |
|
|---|---|---|
| 2022/09 - Atual | Thesis: Identify miRNA-specific small molecules capable of selectively modulate miRNA levels (Co-supervisor Luis Pereira de
Almeida, PhD)
Orientador de Micaela Figueiredo Pintor
|
Master in Pharmaceutical Biotechnology (Mestrado)
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal |
| 2020/09 - Atual | Thesis: Unravelling microRNA dysregulation in Machado-Joseph Disease models
(Co-supervisor Luis Pereira de Almeida, PhD)
Orientador de José Miguel Amaral Pinto
|
Master in Pharmaceutical Biotechnology (Mestrado) |
| 2019/07/01 - Atual | Supervisor of the Post-Doctoral Researcher hired for the project funded by FCT (POCI-01-0145-FEDER-032309) entitled "Role
of microRNA deregulation in Machado-Joseph Disease: On the development of a microRNA-based therapeutic strategy".
Orientador de Diana Isabel da Silva Santos
|
Center for Neurosciences and Cell Biology, Portugal
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal |
| 2022/02/16 - 2023/02/15 | Supervision of MSc Research fellow hired under the project funded by AFM 23755 entitled "Repurposing FDA-approved Drugs as
microRNA-specific modifiers towards a new and promising therapeutic approach for Machado-Joseph disease/spinocerebellar ataxia
type 3 (MJD/SCA3)"
Orientador de Maria Inês Nunes dos Santos
|
Center for Neurosciences and Cell Biology, Portugal
|
| 2021/04/05 - 2021/10/04 | Supervision of MSc Research fellow hired under the project funded by FCT (POCI-01-0145-FEDER-032309) entitled "Role of microRNA
deregulation in Machado-Joseph Disease: On the development of a microRNA-based therapeutic strategy"
Orientador de Maria Inês Nunes dos Santos
|
Center for Neurosciences and Cell Biology, Portugal
Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal |
| 2019/09/02 - 2020/12/16 | Thesis: MicroRNA profiling in human cell-based models of Machado-Joseph disease (Co-supervisor Luis Pereira de Almeida, PhD)
Orientador de Maria Inês Nunes dos Santos
|
Master in Pharmaceutical Biotechnology (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
| 2017/09 - 2018/09/26 | Thesis: The role of autophagy activation mediated by Let-7 in a transgenic mice model of Machado-Joseph Disease (Co-supervisor
Carlos B. Duarte)
Orientador de Beatriz Filipa Varela Estremores
|
Master in Molecular and Cell Biology, University of Coimbra (Mestrado)
Center for Neurosciences and Cell Biology, Portugal
Universidade de Coimbra Departamento de Ciências da Vida, Portugal |
| 2015/09 - 2016/09/09 | Thesis: Autophagy deregulation in models of Parkinson's disease and Machado-Joseph disease (Co-supervisors Rita Perfeito,
PhD and Luis Pereira de Almeida, PhD)
Orientador de Chiara Soricelli
|
Master in Molecular and Cell Biology, University of Coimbra (Mestrado)
Center for Neurosciences and Cell Biology, Portugal
Universidade de Coimbra Departamento de Ciências da Vida, Portugal |
| 2008 - 2009 | Supervision of the project student/scientific internship
Orientador de Cláudia Pinho
|
Bachelor Degree in Biochemistry, Faculty of Science and Technology, University of Coimbra, Portugal |
| 2007 - 2008 | Co-supervision of the project student/scientific internship under the topic "Development of antisense oligonucleotides delivery
systems for splice correction"
Coorientador de Sara Varela Amaral
|
Degree in Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
|
Organização de evento
| Nome do evento Tipo de evento (Tipo de participação) |
Instituição / Organização | |
|---|---|---|
| 2006 - 2006 | Participation in the Organization of the International Symposium: Agents for Molecular therapy: Preparation and applications,
September 15th, 2006 in the School of Sciences, University of Minho, Braga (2006/09/15)
Simpósio (Membro da Comissão Organizadora)
|
Universidade do Minho, Portugal |
Participação em evento
| Descrição da atividade Tipo de evento |
Nome do evento Instituição / Organização |
|
|---|---|---|
| 2023/01/10 - 2023/01/10 | Participating as Doctoral investigator in the Conference "Ética, Integridade e Transparência", January 10th, 2023, Auditório
da Reitoria, University of Coimbra.
Conferência
|
Conference "Ética, Integridade e Transparência"
Universidade de Coimbra, Portugal
|
| 2022/12/19 - 2022/12/19 | Participating as Doctoral investigator in Encontro CIBB 2022 I CIBB Meeting 2022 at the Auditório da Unidade Central do Polo
III
Encontro
|
Encontro CIBB 2022 I CIBB Meeting 2022
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
| 2022/11/19 - 2022/11/19 | Participating as Doctoral Investigator in the Event with MJD patients, INICIATIVA EUROPEIA para a Doença de Machado-Joseph:
Passado, Presente e Futuro, November 19th, 2022, Exploratório, Coimbra
Encontro
|
INICIATIVA EUROPEIA para a Doença de Machado-Joseph: Passado, Presente e Futuro
Exploratório, Portugal
|
| 2022/09/30 - 2022/09/30 | Participated as Doctoral Investigator in the activity "To be or not to be a GreenLab | Que tipo de plástico sou?, Less plastic,
more planet!", European Researchers'Night, September 30, 2022, Baixa de Coimbra.
https://noiteeuropeiadosinvestigadores.uc.pt/
https://www.facebook.com/photo/?fbid=10160084047153908&set=a.436047723907
Exposição
|
European Researchers' Night
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
Center for Neurosciences and Cell Biology, Portugal Universidade de Coimbra, Portugal |
| 2021/12/20 - 2021/12/20 | Participting as a Doctoral Researcher in the CIBB MEETING 2021 (Online via Zoom)
Encontro
|
CIBB MEETING 2021
Center for Neurosciences and Cell Biology, Portugal
|
| 2021/11/24 - 2021/11/24 | Participated as Doctoral Investigator in the activity of Science communication "Falando sobre o cérebro e construção de neurónios"
for students at primary school of Bairro Norton de Matos. Event: https://www.facebook.com/media/set/?set=a.607551827328220&type=3
Exposição
|
Semana da Ciência e Tecnologia 2021
Center for Neurosciences and Cell Biology, Portugal
|
| 2021/11/17 - 2021/11/18 | Participting as Doctoral Investigator in the "2nd Retreat of CIBB's Metabolism, Aging and Disease Area". (Both live and virtual)
Encontro
|
2nd Retreat of CIBB's Metabolism, Aging and Disease Area
Center for Neurosciences and Cell Biology, Portugal
|
| 2021/05/24 - 2021/05/25 | Participating as Doctoral Investigator in the 3rd CIBB Neuroscience and Disease retreat (Online via Zoom)
Encontro
|
3rd CIBB Neuroscience and Disease retreat
Center for Neurosciences and Cell Biology, Portugal
|
| 2021/01/20 - 2021/01/20 | Participating as Doctoral Investigator in the Joint DataClub of Neuroscience and Disease Thematic Line
Conferência
|
Neuroscience and Disease Thematic Line- Joint DataClub
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
| 2020/10/14 - 2020/10/14 | Participating as Doctoral Investigator in the event "O Cérebro e Ambiente: O Impacto da Pandemia"
Seminário
|
"O Cérebro e Ambiente: O Impacto da Pandemia"
Center for Neurosciences and Cell Biology, Portugal
Universidade do Algarve Centro de Investigação em Biomedicina, Portugal Sociedade Portuguesa de Neurociências, Portugal |
| 2020/09/19 - 2020/09/19 | Participating as Doctoral Investigator in the 2nd CIBB INNOVATIVE THERAPIES RETREAT 2020
Conferência
|
2nd CIBB INNOVATIVE THERAPIES RETREAT 2020
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
| 2020/07/08 - 2020/07/08 | Participating as Doctoral Investigator in the CIBB Neuroscience and Disease Online Retreat
Encontro
|
CIBB Neuroscience and Disease Online Retreat
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
| 2020/02/29 - 2020/02/29 | Participation as Doctoral investigator in the event "Doença de Machado-Joseph: do Laboratório para a Sociedade, 2ª Edição"
at the Center for Neuroscience and Cell Biology, University of Coimbra, Portugal, February 29th 2020.
Encontro
|
“Doença de Machado-Joseph: do Laboratório para a Sociedade, 2ª Edição”
Center for Neurosciences and Cell Biology, Portugal
|
| 2019/10/04 - 2019/10/04 | Workshop: How to write a Great Research Paper, and Get it Accepted by a Good Journal.
Oficina (workshop)
|
How to Get Published
Elsevier Ltd, Reino Unido
|
| 2019/10/03 - 2019/10/03 | Workshop: First Aid Course | Formação em primeiros socorros
Oficina (workshop)
|
First Aid Course provided by HIORSE (Hygien, Safety and Health at Work, LDA)
CNC.IBILI, Portugal
|
| 2019/09/27 - 2019/09/27 | Participation as Doctoral investigator in the initiative European Researcher's night at the Jardim Botânico of University
of Coimbra, September 27 2019.
Outro
|
“European Researcher’s night”
Universidade de Coimbra, Portugal
|
| 2019/09/26 - 2019/09/26 | Workshop: AniBio Software
Oficina (workshop)
|
AniBio Software
Center for Neurosciences and Cell Biology, Portugal
|
| 2019/05/13 - 2019/05/13 | Participation as Doctoral Investigator in the initiative "Escola Ciência Viva" at the Rómulo centro de Ciência viva of University
of Coimbra, May 13rd 2019.
Outro
|
“Escola Ciência Viva”
Rómulo Centro de Ciência Viva da Universiade de Coimbra, Portugal
|
| 2019/05/10 - 2019/05/10 | Participating as Doctoral Investigator in the CIBB Neuroscience and Disease 1st Retreat, Miranda do Corvo, Portugal.
Encontro
|
CIBB Neuroscience and Disease 1st Retreat
Centro de Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
|
| 2012 - 2019 | Participation as a Post-Doc Researcher in scientific divulgation related activities as part of the programmes "Brain Awareness
Week" from 2012 - 2019.
Outro
|
“Brain Awareness Week”
Center for Neurosciences and Cell Biology, Portugal
|
| 2012 - 2019 | Participation as a Post-Doc Researcher in scientific divulgation related activities as part of the programme "National Science
and Technology week" from 2012 - 2019.
Outro
|
“National Science and Technology week”
Center for Neurosciences and Cell Biology, Portugal
|
| 2018/03/23 - 2018/03/23 | Overcoming Challenges in Scientific Careers, Biomedical Research Post-Doctoral Forum @ UC, March 23rd, 2018, Faculty of Medicine-
Polo III, University of Coimbra.
Simpósio
|
“Overcoming Challenges in Scientific Careers”, Biomedical Research Post-Doctoral Forum
Universidade de Coimbra, Portugal
|
| 2018/02/28 - 2018/02/28 | Participating as Doctoral Investigator in the event with MJD patients "Doença de Machado-Joseph: do Laboratório para a Sociedade"
at the Center for Neuroscience and Cell Biology, University of Coimbra, Portugal, February 28th 2018.
Encontro
|
“Doença de Machado-Joseph: do Laboratório para a Sociedade”
Center for Neurosciences and Cell Biology, Portugal
|
| 2017/05/22 - 2017/05/23 | Participating as Post-Doc researcher in the 2nd EU joint Programme-Neurodegenerative Disease research (JPND) - European Spinocerebellar
Ataxia Type 3/Machado-Joseph Disease Initiative (ESMI) Meeting, Coimbra, Portugal
Conferência
|
2nd EU joint Programme-Neurodegenerative Disease research (JPND) - European Spinocerebellar Ataxia Type 3/Machado-Joseph
Disease Initiative (ESMI) Meeting
Center for Neurosciences and Cell Biology, Portugal
EU Joint Programme Neurodegenerative Disease Research, Alemanha |
| 2016/12/19 - 2016/12/20 | Participating as Post-Doc researcher in the 1st meeting on Biomedical research at UC, Polo III Auditorium, University of Coimbra,
Portugal.
Encontro
|
1st meeting on Biomedical research
Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal
|
| 2016/11/18 - 2016/11/19 | Participating as Post-Doc researcher in the Brain With]Out[Borders, Museu da Ciência, University of Coimbra, Portugal.
Encontro
|
Brain With]Out[Borders,
Center for Neuroscience and Cell Biology, University of Coimbra (CNC-UC), Portugal
|
| 2015/02/04 - 2015/02/06 | Participating as Post-Doc researcher in the TreatPolyQ Final Meeting, Museum, Coimbra, Portugal.
Conferência
|
TreatPolyQ Final Meeting
Center for Neurosciences and Cell Biology, Portugal
|
| 2012/12/04 - 2012/12/06 | Advanced Fluorescence Microscopy Workshop at the Center for Neuroscience and Cell Biology, University of Coimbra, Portugal,
4-6 December 2012.
Oficina (workshop)
|
Advanced Fluorescence Microscopy Workshop
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
| 2008 - 2012 | Participation as a PhD student in scientific divulgation related activities as part of the programme "Brain Awareness Week"
from 2008 - 2012.
Outro
|
“Brain Awareness Week"
Center for Neurosciences and Cell Biology, Portugal
|
| 2008 - 2012 | Participation as a PhD student in scientific divulgation related activities as part of the programme National Science and
Technology week from 2008 - 2012.
Outro
|
“National Science and Technology week”
Center for Neurosciences and Cell Biology, Portugal
|
| 2009 - 2009 | Participation as PhD student researcher in the event Cientistas ao Palco during the Researchers' Night international initiative
(2009).
Outro
|
“Cientistas ao Palco” during the “Researchers’ Night 2009” international initiative
Center for Neurosciences and Cell Biology, Portugal
|
| 2005/02 - 2006/02 | Participation in the public initiative "Portas Abertas do Departamento de Química- Organização de actividades de divulgação científica", organized by the Biological Chemistry group in February 2005, University of Minho, Braga | "Portas Abertas do Departamento de Química- Organização de actividades de divulgação científica"
Universidade do Minho, Portugal
|
Júri de grau académico
| Tema Tipo de participação |
Nome do candidato (Tipo de grau) Instituição / Organização |
|
|---|---|---|
| 2020/12/16 | Thesis tilte "MICRORNA PROFILING IN HUMAN CELL-BASED MODELS OF MACHADO-JOSEPH DISEASE"
Orientador
|
Maria Inês Nunes dos Santos (Mestrado)
Center for Neurosciences and Cell Biology, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal |
| 2018/09/26 | Thesis title "The role of autophagy activation mediated by Let-7 in a transgenic mice model of Machado-Joseph Disease"
Orientador
|
Beatriz Filipa Varela Estremores (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
|
| 2017/03/21 | Thesis title "Role of microRNA deregulation in the pathogenesis of Machado-Joseph disease"
Arguente
|
Udaya Geetha Vijayakumar (Doutoramento)
Universidade de Coimbra, Portugal
|
| 2016/09/28 | Thesis title "MicroRNA based therapeutic approaches for obesity"
Arguente principal
|
Ana Rita Carvalho Samões (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
|
| 2016/09/09 | Thesis title "Autophagy deregulation in models of Parkinson's disease and Machado-Joseph disease"
Orientador
|
Chiara Soricelli (Mestrado)
Universidade de Coimbra Departamento de Ciências da Vida, Portugal
|
Arbitragem científica em revista
| Nome da revista (ISSN) | Editora | |
|---|---|---|
| 2013/07 - Atual | Acta Neuropathologica (ANP-D-13-00404) | Springer |
Curso / Disciplina lecionado
| Disciplina | Curso (Tipo) | Instituição / Organização | |
|---|---|---|---|
| 2022/04/13 - 2022/04/13 | Lecture on the topic "Thinking small: miRNA-mediated gene silencing and miRNA-based therapeutic approaches" | Advanced Therapies in the Doctoral Programme in Experimental Biology and Biomedicine (PDBEB) (Doutoramento) | Center for Neurosciences and Cell Biology, Portugal Universidade de Coimbra, Portugal |
| 2021/04/21 - 2021/04/21 | Lecture on the topic "Thinking small: miRNA-mediated gene silencing and miRNA-based therapeutic approaches" | Advanced Therapies in the Doctoral Programme in Experimental Biology and Biomedicine (PDBEB) (Doutoramento) | Center for Neurosciences and Cell Biology, Portugal |
| 2020/12/11 - 2020/12/11 | Lecture on the topic "Papel regulador dos microRNAs na expressão génica" | Gene and Cell Therapy course of the graduation in Biomedical Sciences (Licenciatura) | Universidade do Algarve - Campus de Gambelas, Portugal |
| 2020/10/07 - 2020/10/07 | Lecture on the topic "Thinking Small: Towards microRNA-based therapeutics" | Summer Course Metodologias de Investigação Científica (Curso Não Conferente de Grau do IIIUC) | Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal |
| 2020/04/04 - 2020/04/04 | Lecture on the topic "Papel regulador dos microRNAs na expressão génica" | MÓDULO VIII: TERAPÊUTICA MOLECULAR E ENGENHARIA DE TECIDOS of the Master Course of Pharmaceutical Biotechnology (Mestrado) | Universidade de Coimbra Faculdade de Farmácia, Portugal |
| 2019/11/26 - 2019/11/26 | Lecture on the topic "Autophagy in Machado-Joseph Disease" | Curso de Regulação Celular in the Biomedical Investigation Master (Mestrado) | Universidade de Coimbra Faculdade de Medicina, Portugal CNC.IBILI, Portugal |
| 2019/04/23 - 2019/04/23 | Lecture on the topic "MicroRNAs-mediated gene silencing in Neurodegenerative disorders" | Advanced Therapies in the Doctoral Programme in Experimental Biology and Biomedicine (Doutoramento) | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
| 2019/03/30 - 2019/03/30 | Lecture on the topic "Papel regulador dos microRNAs na expressão génica" | Módulo VIII: Terapêutica Molecular e Engenharia de tecidos of the Master Course of Pharmaceutical Biotechnology (Mestrado) | Universidade de Coimbra Faculdade de Farmácia, Portugal |
| 2018/05/08 - 2018/05/08 | Lecture on the topic "MicroRNAs-mediated gene silencing in Neurodegenerative disorders" | Advanced Therapies in the Doctoral Programme in Experimental Biology and Biomedicine (Doutoramento) | Center for Neurosciences and Cell Biology, Portugal |
| 2018/04/21 - 2018/04/21 | Lecture on the topic "Papel regulador dos microRNAs na expressão génica" | Módulo VIII: Terapêutica Molecular e Engenharia de tecidos in the Pharmaceutical Biotechnology Master (Mestrado) | Universidade de Coimbra Faculdade de Farmácia, Portugal |
| 2017/09/26 - 2017/10/06 | Lecture on the topic "Stereotaxic surgery" | Course of Sciences in Laboratory Animals-Module 21: “advanced anaesthesia for surgical or prolonged procedures in mice and rats” and Module 22: “Principles of surgery (skills)” (Curso de Especialização Tecnológica) | CNC.IBILI, Portugal |
| 2017/03/25 - 2017/03/25 | Lecture on the topic "Papel regulador dos microRNAs na expressão génica" | Módulo VIII: Terapêutica Molecular e Engenharia de tecidos in the Pharmaceutical Biotechnology Master (Mestrado) | Universidade de Coimbra Faculdade de Farmácia, Portugal |
| 2016/06/16 - 2016/06/16 | Lecture on the topic "Let-7 activates autophagy and alleviates Machado-Joseph Disease" | Advanced Therapies in the Doctoral Programme in Experimental Biology and Biomedicine (Doutoramento) | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
| 2012/10 - 2012/10 | Lecture on the topic "Western Blot and Immunohistochemistry" | Doctoral Programme in Health Sciences (Doutoramento) | Universidade de Coimbra Faculdade de Medicina, Portugal |
Entrevista (jornal / revista)
| Descrição da atividade | Jornal / Forum | |
|---|---|---|
| 2021/11/24 | "Falando sobre o cérebro e construção de Neurónios" at Primary school of Bairro Norton de Matos | 3.ª edição do "Bairrinho Notícias" |
Entrevista / Programa (rádio / tv)
| Programa | Tema | |
|---|---|---|
| 2017/09/28 - Atual | Interviewed at #IARC2017 under the program International public promotion in Friedreich's Ataxia News, BioNews Services, LLC, of the research projects ongoing | #IARC2017 – MicroRNA Delivered to Brain Seen to Ease Neurological and Motor Problems in Machado-Joseph Mouse Model |
Membro de associação
| Nome da associação | Tipo de participação | |
|---|---|---|
| 2019 - Atual | Sociedade Portuguesa de Neurociências (SPN) membership | Society membership |
| 2019 - Atual | FENS (Federation of European Neuroscience Societies) | |
| 2016 - Atual | European Society of Gene and Cell Therapy (ESGCT) Academic Membership | Society membership |
| 2008 - Atual | Portuguese Biochemical Society (SPB) Membership | Society Membership |
Outro júri / avaliação
| Descrição da atividade | Instituição / Organização | |
|---|---|---|
| 2022/01/27 - 2022/01/27 | President of the Jury for the assignment of a Master Researcher Fellowship (BI - AFM 23755 | Lugus 780589) | Universidade de Coimbra Instituto de Investigação Interdisciplinar, Portugal Center for Neurosciences and Cell Biology, Portugal |
| 2021/02 - 2021/02 | President of the Jury for the assignment of a Master Researcher Fellowship (BI - Atividades de I&D a realizar por estudantes de doutoramento ou mestres inscritos em cursos não conferentes de grau académico_BI: 032309) | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
| 2020/07/28 - 2020/07/28 | Jury member for the assignment of Twelve Research Fellowships (BI- Curso de Verão "Metodologias de investigação científica - I&D: Terapia génica e células estaminais" | 12 BI | Lugus 685385) | Universidade de Coimbra, Portugal |
| 2020/07/28 - 2020/07/28 | Jury member for the assignment of a Initiation Research Fellowship (BII-Curso de Verão "Metodologias de investigação científica - I&D: Terapia génica e células estaminais" | 1 BII | Lugus 685393 | Universidade de Coimbra, Portugal |
| 2019/11/19 - 2019/11/19 | Jury member for the assignment of an MSc researcher fellowship (BIM POCI-01-0145-FEDER-030737) | Center for Neurosciences and Cell Biology, Portugal |
| 2019/05/06 - 2019/05/06 | Jury member of an International selection tender procedure for Doctorate hiring (INV JR 2019 Nº 45. 032309) | Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
| 2019/03/15 - 2019/03/15 | Jury member in the application for Master fellowship with reference BIM 7.3, under the project BrainHealth 2020 - Detecção Precoce, Neuromodulação e Terapias Avançadas para Neuropatologias (CENTRO-01-0145-FEDER-000008) | Center for Neurosciences and Cell Biology, Portugal |
| 2018/11/19 - 2018/11/19 | Jury member in the application for Master fellowship with reference BIM POCI-01-0145-FEDER-030737 | Center for Neurosciences and Cell Biology, Portugal |
Tutoria
| Tópico | Nome do aluno | |
|---|---|---|
| 2020/08 - 2020/10 | Mentoring and Evaluation in the Summer Course "Metodologias de investigação científica - I&D: Terapia génica e células estaminais" | Maria Inês Nunes dos Santos |
| 2019/07 - 2019/09 | Mentoring of Laboratory Rotation | Maria Inês Nunes dos Santos |
| 2019/04/11 - 2019/07/21 | Mentoring of Lab rotation of Master in Pharmaceutical Biotechnology | Maria Inês Nunes dos Santos |
| 2019/04 - 2019/07/12 | Mentoring and Evaluation of Thesis Project Defense "MicroRNA profiling in Machado-Joseph Disease-On the development of a New Therapeutic Strategy" | Maria Inês Nunes dos Santos |
| 2019/04 - 2019/06 | Mentoring of Lab rotation of Master in Pharmaceutical Biotechnology | Maria Pinto |
| 2019/04 - 2019/06 | Mentoring of Lab rotation of Master in Pharmaceutical Biotechnology | Ana Daniela Oliveira |
| 2018/09 - 2019/02 | Mentoring of Labrotation of Master in Pharmaceutical Biotechnology | José Miguel Amaral Pinto |
| 2017/07/05 - 2017/07/28 | Mentoring and Evaluation of the Seminar in Neurobiology I | Beatriz Filipa Varela Estremores |
| 2017/07/01 - 2017/07/14 | Mentoring of the Seminar in Neurobiology II | Beatriz Filipa Varela Estremores |
| 2017/06/05 - 2017/06/30 | Mentoring of Laboratory Rotation III of Master in Molecular and Cell Biology, University of Coimbra | Beatriz Filipa Varela Estremores |
| 2017/01/30 - 2017/02/24 | Mentoring of Laboratory Rotation I of Master in Molecular and Cell Biology, University of Coimbra | Beatriz Filipa Varela Estremores |
| 2008 - 2009 | Laboratory co-supervision of a project student | Liliana Antunes |
| 2008 - 2009 | Laboratorial co-supervision of a project student (Bachelor Degree in Biochemistry, Faculty of Science and Technology, University of Coimbra, Portugal) | Joana Guedes |
Distinções
Prémio
| 2021 | NAF Young Investigator Award 2021
National Ataxia Foundation, Estados Unidos
|
| 2021 | AFM Trampolin Grant - 23755
AFM-Téléthon, França
|
| 2020 | Travel Stipend awarded poster presenter to attend Ataxia Investigators Meeting (AIM) 2020
National Ataxia Foundation, Estados Unidos
|
| 2012 | Post-Doc fellowship (SFRH / BPD / 87552 / 2012) under a highly competitive application
Fundação para a Ciência e a Tecnologia, Portugal
|
| 2008 | PhD fellowship (SFRH/BD/39727/2007) under a highly competitive application
Fundação para a Ciência e a Tecnologia, Portugal
|
| 2003 | Fellowship under PRODEPIII-estágios 2003/2004
Universidade de Coimbra, Portugal
|
Outra distinção
| 2019 | PhD/Doctoral Research contract under DL 57/2016 (NT CNC 2018.01-35, position 8)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia, Portugal |
| 2018 | PhD/Doctoral Research contract under the project POCI-01-0145-FEDER-032309
Fundação para a Ciência e a Tecnologia, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal |
| 2017 | Work selected to be disseminated in Friedreich’s Ataxia News, BioNews Services, LLC "#IARC2017 – MicroRNA Delivered to Brain Seen to Ease Neurological and Motor Problems in Machado-Joseph Mouse Model." |
| 2012 | Research Fellowship under the project PTDC/SAU-FAR/116535/2010
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
| 2007 | Research Fellowship under the project PTDC/BIO/65627/2006
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
|
| 2005 | Research Fellowship under the Project POCTI BIO/47245/2002
Universidade do Minho, Portugal
|