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Ana S. Fernandes has a degree in Pharmaceutical Sciences (2004), a PhD in Toxicology (2010), and was recognised with the European Registered Toxicologist title (2018). She is an Associate Professor at Universidade Lusófona. She is also the Scientific Director for Innovation of CBIOS Research Center. Since 2007 on, she has published 46 full papers in peer-reviewed international journals indexed to ISI/Scopus/PubMed, 14 papers in other peer-reviewed international journals, 4 book chapters, and three dissemination publications. A. Fernandes reviewed approx. seventy papers published in international journals (since 2012; Publons profile: publons.com/a/1324213/). She was the guest editor of two special issues (2019) and is currently editing two other issues. In addition, A. Fernandes is author/co-author of more than forty-five oral communications and over one-hundred posters in international and national meetings. She has received eight awards/honors. A. Fernandes has supervised three PhD theses (completed) and is currently supervising five PhD and five master students. In addition, she has previously supervised thirteen master dissertations and several research trainees, including two post-doc, six visiting PhD students and twenty undergraduates. She participated in several Academic Juries (four PhD, eighteen MSc and twenty eight MPharm). In addition, A. Fernandes has integrated the Evaluation Panel of different calls for research fellowships (CBIOS/FCT), scientific missions (COST actions), and research projects (Croatian Science Foundation - Hrzz-epp). She has participated in five research projects grants and 2 contracts. She was the National delegate for the Management Committee of the COST Actions Action BM1203 ¿ EU-ROS (2013-2016) and CA16112¿NutRedOx (2017-2020), in which she works also as Manager of Science Communication. She is a member of the Scientific Council of the School of Health Sciences and Technologies of Universidade Lusófona where she served also as Vice-President (2012-2014). A. Fernandes is also a member of the National Observatory for Emerging Risks of ASAE (The Portuguese Economic and Food Safety Authority, 2018) and an Expert of the Evaluation Group of Veterinary Medicines (GAMV) of Direção Geral de Alimentação e Veterinária (DGAV, 2018). She is the coordinator of the Advanced Training in Fundamentals of Cell Culture (four editions, between 2012-2018, at CBIOS-ULHT). Finally, Dr Fernandes has integrated the Organizing Committee of several international and national meetings and participates regularly in public outreach activities. Her main line of research is the study of the impact of redox modulators in cancer etiology and progression. She is actively interested in understanding the influence of cellular redox pathways in different features of cancer cells, including proliferation, motility and invasiveness. These studies could contribute to the comprehension of the redox biology of cancer and to the development of novel therapeutic and nutritional strategies.
Identificação

Identificação pessoal

Nome completo
Ana Sofia Gregório Fernandes

Nomes de citação

  • Fernandes, Ana S
  • Fernandes, A. S.
  • Fernandes, Ana Sofia

Identificadores de autor

Ciência ID
CC14-508D-F103
ORCID iD
0000-0001-6350-0641
Google Scholar ID
https://scholar.google.pt/citations?user=0Lj05NQAAAAJ&hl=pt-PT
Researcher Id
H-4789-2013
Scopus Author Id
55937368100

Moradas

  • CBIOS, Escola de Ciências e Tecnologias da Saúde da Universidade Lusófona de Humanidades e Tecnologias, COFAC. Campo Grande, 376, 1749-024, Lisboa, Lisboa, Portugal (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Farmacologia e Farmácia
  • Ciências Médicas e da Saúde - Ciências da Saúde - Nutrição e Dietética

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Italiano Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1)
Francês Utilizador elementar (A1) Utilizador independente (B1) Utilizador elementar (A1) Utilizador elementar (A1)
Formação
Grau Classificação
2010
Concluído
Pharmacy, specialization in Toxicology (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"Modulation of oxidative stress by superoxide dismutase mimetics" (TESE/DISSERTAÇÃO)
Aprovado com distinção e louvor por unanimidade
2004
Concluído
Ciências Farmacêuticas (Licenciatura)
Universidade de Lisboa Faculdade de Farmácia, Portugal
"-" (TESE/DISSERTAÇÃO)
16/20
Percurso profissional

Ciência

2012 - Atual Investigador principal (carreira) (Investigação)
Universidade Lusófona de Humanidades e Tecnologias, Portugal

Docência no Ensino Superior

2020/06/10 - Atual Professor Associado (Docente Universitário)
Universidade Lusófona de Humanidades e Tecnologias, Portugal
2012/01/02 - 2020/06/09 Professor Auxiliar (Docente Universitário)
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
2013 - 2016 Professor Coordenador (Docente Ensino Superior Politécnico)
Escola Superior de Saúde Ribeiro Sanches, Portugal

Cargos e Funções

2013 - 2016 Conselho científico/técnico-científico ou orgão correspondente
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
Projetos

Bolsa

Designação Financiadores
2020 - 2020/12/31 Redox modulation of cancer progression
FIPID - COFAC Grant Programme 2019/2020
Investigador responsável
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
cofac - cooperativa de formação e animação cultural crl
2011 - 2012/01 EXPLOITING THE INTERPLAY BETWEEN CELLULAR REDOX BALANCE AND BREAST CANCER INVASIVENESS
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBPD2%F690422%F2010/PT
Bolseiro de Pós-Doutoramento
Universidade de Lisboa Instituto de Investigação do Medicamento, Portugal
Fundação para a Ciência e a Tecnologia
2007 - 2010/12/14 MODULATION OF OXIDATIVE STRESS BY METAL MACROCYCLIC COMPLEXES
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F287732%F2006/PT
Bolseiro de Doutoramento
Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia
2003 - 2005 Macrocyclic compounds selective for heavy metals poisoning: Cd(II), Hg(II) and Pb(II).
info:eu-repo/grantAgreement/FCT/POCI/49114/PT
Bolseiro de Investigação
Universidade de Lisboa Faculdade de Farmácia, Portugal
Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2019 - 2019/01/01 Centro de Investigação em Biociências e Tecnologias da Saúde
UID/DTP/04567/2019
Investigador
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
Associação para a Inovação e Desenvolvimento da FCT
2016 - 2018/12/31 Centro de Investigação em Biociências e Tecnologias da Saúde
UID/DTP/04567/2016
Investigador
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal
Produções

Publicações

Artigo em revista
  1. Sofia Ramos; Ana Sofia Fernandes; Nuno Saraiva. "Gene expression and survival analysis in cancer research using online open access platforms: a comparative analysis". Biomedical and Biopharmaceutical Research Journal (2020): https://doi.org/10.19277/bbr.17.2.247.
    10.19277/bbr.17.2.247
  2. Raquel Rodrigues dos Santos; João Gregório; Liliana Castanheira; Ana S. Fernandes. "Exploring Volatile Organic Compound Exposure and Its Association with Wheezing in Children under 36 Months: A Cross-Sectional Study in South Lisbon, Portugal". International Journal of Environmental Research and Public Health 17 18 (2020): 6929-6929. https://doi.org/10.3390/ijerph17186929.
    10.3390/ijerph17186929
  3. Vera M. S. Isca; Joana Andrade; Ana Sofia Fernandes; Paulo Paixão; Clara Uriel; Ana María Gómez; Noélia Duarte; Patrícia Rijo. "In Vitro Antimicrobial Activity of Isopimarane-Type Diterpenoids". Molecules (2020): https://doi.org/10.3390/molecules25184250.
    10.3390/molecules25184250
  4. Carla Pires; Ana Fernandes. "Adverse Effects of Natural Products: A Brief Pre-Systematic Review". Current Nutraceuticals (2020): https://doi.org/10.2174/2665978601999200702163914.
    10.2174/2665978601999200702163914
  5. Rita Manguinhas; Ana S. Fernandes; João G. Costa; Nuno Saraiva; Sérgio P. Camões; Nuno Gil; Rafael Rosell; et al. "Impact of the APE1 Redox Function Inhibitor E3330 in Non-Small Cell Lung Cancer Cells Exposed to Cisplatin: Increased Cytotoxicity and Impairment of Cell Migration and Invasion". Antioxidants 9 6 (2020): 550-550. https://doi.org/10.3390/antiox9060550.
    10.3390/antiox9060550
  6. Marisa Nicolai; Joana Mota; Ana S. Fernandes; Filipe Pereira; Paula Pereira; Catarina P. Reis; Maria Valéria Robles Velasco; et al. "Assessment of the Potential Skin Application of Plectranthus ecklonii Benth.". Pharmaceuticals (2020): https://doi.org/10.3390/ph13060120.
    10.3390/ph13060120
  7. Patrícia Rijo; Milica Pešic; Ana S. Fernandes; Cláudia N. Santos. "Natural Products: Optimizing Cancer Treatment through Modulation of Redox Balance". Oxidative Medicine and Cellular Longevity (2020): https://doi.org/10.1155/2020/2407074.
    10.1155/2020/2407074
  8. Nuno Saraiva; João G. Costa; Catarina Reis; Nuno Almeida; Patrícia Rijo; Ana Sofia Fernandes. "Anti-Migratory and Pro-Apoptotic Properties of Parvifloron D on Triple-Negative Breast Cancer Cells". Biomolecules (2020): https://doi.org/10.3390/biom10010158.
    10.3390/biom10010158
  9. Gabriel Satoto; Ana Sofia Fernandes; Nuno Saraiva; Fernando Santos; Nuno Neng; José Manuel Nogueira; Tânia Santos de Almeida; Maria Eduarda Araujo. "An Overview on the Properties of Ximenia Oil Used as Cosmetic in Angola". Biomolecules 10 1 (2019): 18-18. https://doi.org/10.3390/biom10010018.
    10.3390/biom10010018
  10. João G. Costa; Nuno Saraiva; Ines Batinic-Haberle; Matilde Castro; Nuno G. Oliveira; Ana S. Fernandes. "The SOD Mimic MnTnHex-2-PyP5+ Reduces the Viability and Migration of 786-O Human Renal Cancer Cells". Antioxidants 8 10 (2019): 490-490. https://doi.org/10.3390/antiox8100490.
    10.3390/antiox8100490
  11. Susana Proença; Bernardo Antunes; Rita C. Guedes; Filipa Ramilo-Gomes; M. Fátima Cabral; Judite Costa; Ana S. Fernandes; et al. "Pyridine-Containing Macrocycles Display MMP-2/9 Inhibitory Activity and Distinct Effects on Migration and Invasion of 2D and 3D Breast Cancer Models". International Journal of Molecular Sciences (2019): https://doi.org/10.3390/ijms20205109.
    10.3390/ijms20205109
  12. João Guilherme Costa; Bojana Vidovic; Nuno Saraiva; Maria do Céu Costa; Giorgia Del Favero; Doris Marko; Nuno G. Oliveira; Ana Sofia Fernandes. "Contaminants: a dark side of food supplements?". Free Radical Research (2019): https://doi.org/10.1080/10715762.2019.1636045.
    10.1080/10715762.2019.1636045
  13. Marisa Nicolai; Nuno Almeida; Patricia Rijo; João Guilherme Costa; Nuno Saraiva; Ana Sofia Fernandes. "Cytotoxic effect of antioxidants found in food from plant origin on human osteosarcoma U2OS Cells". Journal Biomedical and Biopharmaceutical Research (2019): https://doi.org/10.19277/BBR.16.1.202.
    10.19277/BBR.16.1.202
  14. Raquel Rodrigues dos Santos; João Gregório; Liliana Castanheira; Ana Fernandes. "The association of housing conditions with wheezing in children up to 36 monthold: an observational study in Arco Ribeirinho region". Journal Biomedical and Biopharmaceutical Research (2019): https://doi.org/10.19277/BBR.16.1.198.
    10.19277/BBR.16.1.198
  15. Carla Pires; Ana Fernandes. "Ceftriaxone: clinical review, consumption in Portugal and safety alerts". Journal Biomedical and Biopharmaceutical Research (2018): https://doi.org/10.19277/BBR.15.2.189.
    10.19277/BBR.15.2.189
  16. Fernandes, Ana S. "The manganese(III) porphyrin MnTnHex-2-PyP5+ modulates intracellular ROS and breast cancer cell migration: Impact on doxorubicin-treated cells.". Redox Biology (2018): https://europepmc.org/articles/PMC6222139.
    10.1016/j.redox.2018.10.016
  17. Nuno Almeida; Lara Ribeiro; João G. Costa; Patricia Rijo; M. Eduarda Araújo; Nuno Saraiva; Ana Sofia Fernandes. "Cytotoxicity of N-nitrosoguanidines in a breast cancer cell model". Journal Biomedical and Biopharmaceutical Research (2017): https://doi.org/10.19277/BBR.14.2.159.
    10.19277/BBR.14.2.159
  18. Raquel Rodrigues dos Santos; Ana S. Fernandes; Liliana Castanheira. "Development of a strategy to identify the characteristics of babie‘s rooms associated with volatile organic compounds and with the occurrence of wheezing". Journal Biomedical and Biopharmaceutical Research (2017): https://doi.org/10.19277/BBR.14.1.146.
    10.19277/BBR.14.1.146
  19. Egea, J.; Fabregat, I.; Frapart, Y.M.; Ghezzi, P.; Görlach, A.; Kietzmann, T.; Kubaichuk, K.; et al. "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)". Redox Biology 13 (2017): 94-162. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020032301&partnerID=MN8TOARS.
    10.1016/j.redox.2017.05.007
  20. Guerreiro, P.S.; Corvacho, E.; Costa, J.G.; Saraiva, N.; Fernandes, A.S.; Castro, M.; Miranda, J.P.; Oliveira, N.G.. "The APE1 redox inhibitor E3330 reduces collective cell migration of human breast cancer cells and decreases chemoinvasion and colony formation when combined with docetaxel". Chemical Biology and Drug Design 90 4 (2017): 561-571. http://www.scopus.com/inward/record.url?eid=2-s2.0-85018948782&partnerID=MN8TOARS.
    10.1111/cbdd.12979
  21. Santos de Almeida, T.; Júlio, A.; Saraiva, N.; Fernandes, A.S.; Araújo, M.E.M.; Baby, A.R.; Rosado, C.; Mota, J.P.. "Choline- versus imidazole-based ionic liquids as functional ingredients in topical delivery systems: cytotoxicity, solubility, and skin permeation studies". Drug Development and Industrial Pharmacy 43 11 (2017): 1858-1865. http://www.scopus.com/inward/record.url?eid=2-s2.0-85023747624&partnerID=MN8TOARS.
    10.1080/03639045.2017.1349788
  22. Egea, J.; Fabregat, I.; Frapart, Y.M.; Ghezzi, P.; Görlach, A.; Kietzmann, T.; Kubaichuk, K.; et al. "Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162]". Redox Biology (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85032289195&partnerID=MN8TOARS.
    10.1016/j.redox.2017.10.001
  23. Francisco Caldeira; João Costa; Patricia Rijo; Nuno Saraiva; Ana Fernandes. "Xanthine Oxidase Inhibitory Activity of a Plectranthus saccatus aqueous extract". Journal Biomedical and Biopharmaceutical Research (2016): https://doi.org/10.19277/bbr.13.2.143.
    10.19277/bbr.13.2.143
  24. João G. Costa; Nuno Saraiva; Patrícia S. Guerreiro; Henriqueta Louro; Maria J. Silva; Joana P. Miranda; Matilde Castro; et al. "Ochratoxin A-induced cytotoxicity, genotoxicity and reactive oxygen species in kidney cells: An integrative approach of complementary endpoints". Food and Chemical Toxicology 87 (2016): 65-76. https://doi.org/10.1016%2Fj.fct.2015.11.018.
    10.1016/j.fct.2015.11.018
  25. Guerreiro, P.S.; Estácio, S.G.; Antunes, F.; Fernandes, A.S.; Pinheiro, P.F.; Costa, J.G.; Castro, M.; et al. "Structure-based virtual screening toward the discovery of novel inhibitors of the DNA repair activity of the human apurinic/apyrimidinic endonuclease 1". Chemical Biology and Drug Design 88 6 (2016): 915-925. http://www.scopus.com/inward/record.url?eid=2-s2.0-84987862345&partnerID=MN8TOARS.
    10.1111/cbdd.12826
  26. Silva, C.O.; Molpeceres, J.; Batanero, B.; Fernandes, A.S.; Saraiva, N.; Costa, J.G.; Rijo, P.; et al. "Functionalized diterpene parvifloron D-loaded hybrid nanoparticles for targeted delivery in melanoma therapy". Therapeutic Delivery 7 8 (2016): 521-544. http://www.scopus.com/inward/record.url?eid=2-s2.0-84979515564&partnerID=MN8TOARS.
    10.4155/tde-2016-0027
  27. Silva, C.O.; Rijo, P.; Molpeceres, J.; Ascensão, L.; Roberto, A.; Fernandes, A.S.; Gomes, R.; et al. "Bioproduction of gold nanoparticles for photothermal therapy". Therapeutic Delivery 7 5 (2016): 287-304. http://www.scopus.com/inward/record.url?eid=2-s2.0-84964937758&partnerID=MN8TOARS.
    10.4155/tde-2015-0011
  28. Neto, Í.; Andrade, J.; Fernandes, A.S.; Pinto Reis, C.; Salunke, J.K.; Priimagi, A.; Candeias, N.R.; Rijo, P.. "Multicomponent Petasis-borono Mannich Preparation of Alkylaminophenols and Antimicrobial Activity Studies". ChemMedChem (2016): 2015-2023. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988448120&partnerID=MN8TOARS.
    10.1002/cmdc.201600244
  29. Silva, C.O.; Petersen, S.B.; Reis, C.P.; Rijo, P.; Molpeceres, J.; Fernandes, A.S.; Gonçalves, O.; et al. "EGF functionalized polymer-coated gold nanoparticles promote EGF photostability and EGFR internalization for photothermal therapy". PLoS ONE 11 10 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84992755798&partnerID=MN8TOARS.
    10.1371/journal.pone.0165419
  30. Wagemaker, T.A.L.; Campos, P.M.B.G.M.; Fernandes, A.S.; Rijo, P.; Nicolai, M.; Roberto, A.; Rosado, C.; et al. "Unsaponifiable matter from oil of green coffee beans: cosmetic properties and safety evaluation". Drug Development and Industrial Pharmacy 42 10 (2016): 1695-1699. http://www.scopus.com/inward/record.url?eid=2-s2.0-84965010204&partnerID=MN8TOARS.
    10.3109/03639045.2016.1165692
  31. Oliveira, C.A.D.; Peres, D.D.; Graziola, F.; Chacra, N.A.B.; Araújo, G.L.B.D.; Flórido, A.C.; Mota, J.; et al. "Cutaneous biocompatible rutin-loaded gelatin-based nanoparticles increase the SPF of the association of UVA and UVB filters". European Journal of Pharmaceutical Sciences 81 (2016): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943265035&partnerID=MN8TOARS.
    10.1016/j.ejps.2015.09.016
  32. Fernandes, Ana. "Role of the Copper(II) Complex Cu[15]pyN5in Intracellular ROS and Breast Cancer Cell Motility and Invasion". Chemical Biology & Drug Design (2015):
    10.1111/cbdd.12521
  33. Sara Rosa; V. Correia; I. Ribeiro; Patricia Rijo; F. Simões; N. Saraiva; A. Fernandes. "In vitro antioxidant properties of the diterpenes Parvifloron D and 7a-acetoxy-6ß- hydroxyroyleanone". Journal Biomedical and Biopharmaceutical Research (2015): https://doi.org/10.19277/BBR.12.1.104.
    10.19277/BBR.12.1.104
  34. Silva, C.O.; Rijo, P.; Molpeceres, J.; Figueiredo, I.V.; Ascensão, L.; Fernandes, A.S.; Roberto, A.; Reis, C.P.. "Polymeric nanoparticles modified with fatty acids encapsulating betamethasone for anti-inflammatory treatment". International Journal of Pharmaceutics 493 1-2 (2015): 271-284. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938828795&partnerID=MN8TOARS.
    10.1016/j.ijpharm.2015.07.044
  35. Pereira, F.; Baptista, R.; Ladeiras, D.; Madureira, A.M.; Teixeira, G.; Rosado, C.; Fernandes, A.S.; et al. "Production and characterization of nanoparticles containing methanol extracts of Portuguese Lavenders". Measurement: Journal of the International Measurement Confederation 74 (2015): 170-177. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938387201&partnerID=MN8TOARS.
    10.1016/j.measurement.2015.07.029
  36. Miranda, J.P.; Filipe, E.; Fernandes, A.S.; Almeida, J.M.; Martins, J.P.; De La Fuente, A.; Abal, M.; et al. "The human umbilical cord tissue-derived MSC population UCX® promotes early motogenic effects on keratinocytes and fibroblasts and G-CSF-mediatedmobilization of BM-MSCS when transplanted in vivo". Cell Transplantation 24 5 (2015): 865-877. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928952810&partnerID=MN8TOARS.
    10.3727/096368913X676231
  37. Wagemaker, T.A.L.; Rijo, P.; Rodrigues, L.M.; Maia Campos, P.M.B.G.; Fernandes, A.S.; Rosado, C.. "Integrated approach in the assessment of skin compatibility of cosmetic formulations with green coffee oil". International Journal of Cosmetic Science 37 5 (2015): 506-510. http://www.scopus.com/inward/record.url?eid=2-s2.0-84940953144&partnerID=MN8TOARS.
    10.1111/ics.12225
  38. Patricia Rijo; Lara Ribeiro; Ana Sofia Fernandes; Célia Faustino. "A didactic approach for quantification of diazepam tablets by UV spectrophotometry". Journal Biomedical and Biopharmaceutical Research (2014): https://doi.org/10.19277/BBR.11.1.83.
    10.19277/BBR.11.1.83
  39. Reis, C.P.; Martinho, N.; Rosado, C.; Fernandes, A.S.; Roberto, A.. "Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment". Drug Development and Industrial Pharmacy 40 3 (2014): 409-417. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893929708&partnerID=MN8TOARS.
    10.3109/03639045.2013.767826
  40. Rijo, P.; Matias, D.; Fernandes, A.S.; Simões, M.F.; Nicolai, M.; Reis, C.P.. "Antimicrobial plant extracts encapsulated into polymeric beads for potential application on the skin". Polymers 6 2 (2014): 479-490. http://www.scopus.com/inward/record.url?eid=2-s2.0-84899496961&partnerID=MN8TOARS.
    10.3390/polym6020479
  41. Torres, N.; Gonçalves, S.; Fernandes, A.S.; Machado, J.F.; De Brito, M.J.V.; Oliveira, N.G.; Castro, M.; Costa, J.; Cabral, M.F.. "[15]aneN4S: Synthesis, thermodynamic studies and potential applications in chelation therapy". Molecules 19 1 (2014): 550-567. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893030039&partnerID=MN8TOARS.
    10.3390/molecules19010550
  42. Bandarra, S.; Fernandes, A.S.; Magro, I.; Guerreiro, P.S.; Pingarilho, M.; Churchwell, M.I.; Gil, O.M.; et al. "Erratum: Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells (Mutagenesis (2013) 28:6 (721-729))". Mutagenesis 29 1 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84891367154&partnerID=MN8TOARS.
    10.1093/mutage/get059
  43. Tais A. L. Wagemaker; Catarina Rosado; Jirrah P. Andrade; Ana Sofia Fernandes; Patricia Rijo; Patricia Maia Campos; Luis Monteiro Rodrigues. "Evaluation of the sensory properties of a cosmetic formulation containing green coffee oi". Journal Biomedical and Biopharmaceutical Research (2013): https://doi.org/10.19277/BBR.10.1.56.
    10.19277/BBR.10.1.56
  44. Ana S. Fernandes; Amílcar Roberto; Paula Paixão; Henrique Silva. "CBiOS Science Sessions - 2013 - Proceedings". Journal Biomedical and Biopharmaceutical Research (2013): https://doi.org/10.19277/BBR.10.1.57.
    10.19277/BBR.10.1.57
  45. Fernandes, A. S.; Florido, A.; Cipriano, M.; Batinic-Haberle, I.; Miranda, J.; Saraiva, N.; Guerreiro, P. S.; Castro, M.; Oliveira, N. G.. "Combined effect of the SOD mimic MnTnHex-2-PyP5+ and doxorubicin on the migration and invasiveness of breast cancer cells". Toxicology Letters 221 (2013): S70-S71.
    10.1016/j.toxlet.2013.05.052
  46. Miranda, J. P.; Cipriano, M.; Fernandes, A. S.; Castro, M.; Oliveira, N. G.. "In vitro cytotoxicity assessment using three-dimensional cell cultures of MCF10A cells". Toxicology Letters 221 (2013): S144-S144.
    10.1016/j.toxlet.2013.05.289
  47. Costa, J. G.; Fernandes, A. S.; Guerreiro, P. S.; Filipe, E.; Miranda, J. P.; Castro, M.; Oliveira, N. G.. "Induction of micronuclei and cytotoxic effects of ochratoxin A in Vero cells". Toxicology Letters 221 (2013): S121-S121.
    10.1016/j.toxlet.2013.05.214
  48. Guerreiro, P. S.; Miranda, J. P.; Fernandes, A. S.; Costa, J. G.; Castro, M.; Oliveira, N. G.. "Effect of APE1 inhibitors on the cytotoxicity and genotoxicity of doxorubicin in MDA-MB-231 cells". Toxicology Letters 221 (2013): S92-S92.
    10.1016/j.toxlet.2013.05.120
  49. Martins, I.L.; Miranda, J.P.; Oliveira, N.G.; Fernandes, A.S.; Gonçalves, S.; Antunes, A.M.M.. "Synthesis and biological activity of 6-selenocaffeine: Potential modulator of chemotherapeutic drugs in breast cancer cells". Molecules 18 5 (2013): 5251-5264. http://www.scopus.com/inward/record.url?eid=2-s2.0-84878289780&partnerID=MN8TOARS.
    10.3390/molecules18055251
  50. Pingarilho, M.; Oliveira, N.G.; Martins, C.; Gomes, B.C.; Fernandes, A.S.; Martins, V.; Labilloy, A.; et al. "Induction of sister chromatid exchange by acrylamide and glycidamide in human lymphocytes: Role of polymorphisms in detoxification and DNA-repair genes in the genotoxicity of glycidamide". Mutation Research - Genetic Toxicology and Environmental Mutagenesis 752 1-2 (2013): 1-7. http://www.scopus.com/inward/record.url?eid=2-s2.0-84875390595&partnerID=MN8TOARS.
    10.1016/j.mrgentox.2012.12.013
  51. Bandarra, S.; Fernandes, A.S.; Magro, I.; Guerreiro, P.S.; Pingarilho, M.; Churchwell, M.I.; Gil, O.M.; et al. "Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells". Mutagenesis 28 6 (2013): 721-729. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888626357&partnerID=MN8TOARS.
    10.1093/mutage/get052
  52. Guerreiro, P.S.; Fernandes, A.S.; Costa, J.G.; Castro, M.; Miranda, J.P.; Oliveira, N.G.. "Differential effects of methoxyamine on doxorubicin cytotoxicity and genotoxicity in MDA-MB-231 human breast cancer cells". Mutation Research - Genetic Toxicology and Environmental Mutagenesis 757 2 (2013): 140-147. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885858884&partnerID=MN8TOARS.
    10.1016/j.mrgentox.2013.08.003
  53. Tais A. L. Wagemaker; Ana S. Fernandes; Patrícia Maia Campos; Luís Monteiro Rodrigues; Patrícia Rijo. "Evaluation of antioxidant and antimicrobial activities of green coffee oil in cosmetic formulations". Journal Biomedical and Biopharmaceutical Research (2012): https://doi.org/10.19277/BBR.9.2.43.
    10.19277/BBR.9.2.43
  54. Patrícia Rijo; Ana Sofia Fernandes; Fátima Simões; Lidia Pinheiro. "Evaluation of diterpenoids from P. ornatus as potential COX-1 inhibitors". Journal Biomedical and Biopharmaceutical Research (2012): https://doi.org/10.19277/bbr.9.1.33.
    10.19277/bbr.9.1.33
  55. Gonçalves, S.; Fernandes, A.S.; Oliveira, N.G.; Marques, J.; Costa, J.; Fátima Cabral, M.; Miranda, J.; et al. "Cytotoxic effects of cadmium in mammary epithelial cells: Protective role of the macrocycle [15]pyN 5". Food and Chemical Toxicology 50 6 (2012): 2180-2187. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860341449&partnerID=MN8TOARS.
    10.1016/j.fct.2012.04.006
  56. Oliveira, N. G.; Magro, I.; Fernandes, A. S.; Miranda, J. P.; Guerreiro, P. S.; Castro, M.. "Effect of DNA repair inhibitors on the cytotoxicity induced by glycidamide". Toxicology Letters 211 (2012): S110-S110.
    10.1016/j.toxlet.2012.03.410
  57. Miranda, J.; Filipe, E.; Barcia, R.; Cruz, H.; Cruz, P.; Fernandes, A. S.; Cipriano, M.; Castro, M.; Santos, M.. "Beneficial effects of mesenchymal stem cells conditioned media on skin regeneration". Toxicology Letters 211 (2012): S44-S44.
    10.1016/j.toxlet.2012.03.181
  58. Fernandes, A.S.; Costa, J.; Gaspar, J.; Rueff, J.; Cabral, M.F.; Cipriano, M.; Castro, M.; Oliveira, N.G.. "Development of pyridine-containing macrocyclic copper(II) complexes: Potential role in the redox modulation of oxaliplatin toxicity in human breast cells". Free Radical Research 46 9 (2012): 1157-1166. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864662657&partnerID=MN8TOARS.
    10.3109/10715762.2012.695869
  59. Pingarilho, M.; Oliveira, N.G.; Martins, C.; Fernandes, A.S.; De Lima, J.P.; Rueff, J.; Gaspar, J.F.. "Genetic polymorphisms in detoxification and DNA repair genes and susceptibility to glycidamide-induced DNA damage". Journal of Toxicology and Environmental Health - Part A: Current Issues 75 13-15 (2012): 920-933. http://www.scopus.com/inward/record.url?eid=2-s2.0-84864030648&partnerID=MN8TOARS.
    10.1080/15287394.2012.690709
  60. Ana Sofia Fernandes; Matilde Castro; Nuno Guerreiro Oliveira. "Oxidative stress and antioxidant defences – a pedagogical review". Journal Biomedical and Biopharmaceutical Research 8 1 (2011): 97-108. https://doi.org/10.19277/bbr.8.1.8.
    10.19277/bbr.8.1.8
  61. Ramos, D.L.; Gaspar, J.F.; Pingarilho, M.; Gil, O.M.; Fernandes, A.S.; Rueff, J.; Oliveira, N.G.. "Genotoxic effects of doxorubicin in cultured human lymphocytes with different glutathione S-transferase genotypes". Mutation Research - Genetic Toxicology and Environmental Mutagenesis 724 1-2 (2011): 28-34. http://www.scopus.com/inward/record.url?eid=2-s2.0-79961021312&partnerID=MN8TOARS.
    10.1016/j.mrgentox.2011.04.013
  62. Fernandes, A.S.; Cabral, M.F.; Costa, J.; Castro, M.; Delgado, R.; Drew, M.G.B.; Félix, V.. "Two macrocyclic pentaaza compounds containing pyridine evaluated as novel chelating agents in copper(II) and nickel(II) overload". Journal of Inorganic Biochemistry 105 3 (2011): 410-419. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952991779&partnerID=MN8TOARS.
    10.1016/j.jinorgbio.2010.11.014
  63. Fernandes, A.S.; Serejo, J.; Gaspar, J.; Cabral, F.; Bettencourt, A.F.; Rueff, J.; Castro, M.; Costa, J.; Oliveira, N.G.. "Oxidative injury in V79 Chinese hamster cells: Protective role of the superoxide dismutase mimetic MnTM-4-PyP". Cell Biology and Toxicology 26 2 (2010): 91-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952238992&partnerID=MN8TOARS.
    10.1007/s10565-009-9120-3
  64. Fernandes, A.S.; Gaspar, J.; Cabral, M.F.; Rueff, J.; Castro, M.; Batinic-Haberle, I.; Costa, J.; Oliveira, N.G.. "Protective role of ortho-substituted Mn(III) N-alkylpyridylporphyrins against the oxidative injury induced by tert-butylhydroperoxide". Free Radical Research 44 4 (2010): 430-440. http://www.scopus.com/inward/record.url?eid=2-s2.0-77949374760&partnerID=MN8TOARS.
    10.3109/10715760903555844
  65. Oliveira, N.G.; Pingarilho, M.; Martins, C.; Fernandes, A.S.; Vaz, S.; Martins, V.; Rueff, J.; Gaspar, J.F.. "Cytotoxicity and chromosomal aberrations induced by acrylamide in V79 cells: Role of glutathione modulators". Mutation Research - Genetic Toxicology and Environmental Mutagenesis 676 1 (2009): 87-92. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349214201&partnerID=MN8TOARS.
    10.1016/j.mrgentox.2009.04.009
  66. Fernandes, A.S.; Gaspar, J.; Cabral, M.F.; Caneiras, C.; Guedes, R.; Rueff, J.; Castro, M.; Costa, J.; Oliveira, N.G.. "Macrocyclic copper(II) complexes: Superoxide scavenging activity, structural studies and cytotoxicity evaluation". Journal of Inorganic Biochemistry 101 5 (2007): 849-858. http://www.scopus.com/inward/record.url?eid=2-s2.0-34047109133&partnerID=MN8TOARS.
    10.1016/j.jinorgbio.2007.01.013
Capítulo de livro
  1. Ferreira-Pêgo, Cíntia; Vidovic B; Oliveira NG; Fernandes, Ana S; Costa JG. "Fruit and vegetable juices and Breast Cancer". In Cancer: Oxidative Stress and Dietary Antioxidants. Elsevier - Academic Press, 2020.
    Aceite para publicação
  2. Oliveira NG; Miranda JP; Costa JG; Rodrigues, António Sebastião; Castro, Matilde; Fernandes, Ana S. "Toxicodinâmica". In Toxicologia Fundamental, editado por Oliveira RD, Carvalho FD, Bastos ML, 35-63. Portugal: Lidel, 2018.
    Publicado
  3. Fernandes, Ana S.; Saraiva, Nuno; Oliveira, Nuno G.. "Redox Therapeutics in Breast Cancer: Role of SOD Mimics". In Oxidative Stress in Applied Basic Research and Clinical Practice, 451-467. Estados Unidos: Springer International Publishing, 2016.
    Publicado • 10.1007/978-3-319-30705-3_18
  4. Oliveira, N.G.; Miranda, J.P.; Fernandes, Ana S; Castro, Matilde. "Biomarcadores em Toxicologia". In Toxicologia Forense, editado por R. J. Dinis-Oliveira, F. D. Carvalho & M. L. Bastos, 79-101. Lisboa, Portugal: Pactor, 2015.
    Publicado
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2019/05/01 - Atual UNREAD - RadiUm-223 iN metastatic pRostatE cAncer: searching the keys beyond clinical eviDence
Coorientador
Programa Doutoral em Ciências da Saúde (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2019/01/01 - Atual Expression profile of cellular redox and calcium signalling-related genes: role in breast cancer progression
Coorientador
Ciencias de la Salud (Doutoramento)
Universidad de Alcalá de Henares Facultad de Medicina y Ciencias de la Salud, Espanha
2016 - 2019/12 Role of redox-active SOD mimics on the migration and invasion capabilities of human breast cancer cells
Orientador
Farmácia (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2017/09/01 - 2019/05/06 Thymoquinone - a food compound with several applications in human health: potential effect in renal cancer
Coorientador
Master in Food Quality and Health (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2019 - 2019 Autovigilância e acompanhamento de diabéticos tipo 2 pelo farmacêutico comunitário
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2019 - 2019 Terapêutica farmacológica na perturbação da hiperactividade e défice de atenção
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2019 - 2019 Compostos de origem alimentar com potencial efeito na progressão do cancro
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2013/09/01 - 2018/01/08 Redox modulation by SOD mimics in renal cancer: from etiology to progression
Orientador
Ciencias de la Salud (Doutoramento)
Universidad de Alcalá de Henares Facultad de Medicina y Ciencias de la Salud, Espanha
2018 - 2018 Abordagens terapêuticas no carcinoma renal: Estado da Arte
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2018 - 2018 Artrite reumatóide: terapêutica atual e perspetivas futuras
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2014 - 2017/12 Qualidade do ar interior em quartos de bebés: estudo das concentrações de compostos orgânicos voláteis
Orientador
Ciencias de La Salud (Doutoramento)
Universidad de Alcalá de Henares, Espanha
2017 - 2017 Fármacos anti-metastização: da investigação à prática clínica
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2015 - 2015 Estudo da potencial acção antitumoral da Parviflorona D
Orientador
Ciências Farmacêuticas (Mestrado)
Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2019/10/10 - 2019/10/11 Physioma 2019 - First Meeting of the Portuguese Physiological Society (2019/10/10 - 2019/10/11)
Conferência (Membro da Comissão Organizadora)
Sociedade Portuguesa de Fisiologia, Portugal
2019/10/02 - 2019/10/04 “Nutrition and Ageing” (NutRedOx COST Action) (2019/10/02 - 2019/10/04)
Encontro (Presidente da Comissão Organizadora)
European Cooperation in Science and Technology, Bélgica
2019/04/01 - 2019/04/02 Mechanobiology of migrating Cells: From Basic Science to the Clinic (EuroCellNet COST action) (2019/04/01 - 2019/04/02)
Encontro (Membro da Comissão Organizadora)
European Cooperation in Science and Technology, Bélgica
2018/06/04 - 2018/06/07 19th Biennial Meeting of the Society for Free Radical Research International (2018/06/04 - 2018/06/07)
Congresso (Membro da Comissão Organizadora)
Society for Free Radical Research, Noruega
2016/04/11 - 2016/04/13 ROS in drug discovery: from target identification to redox-based therapeutics (COST Action EU-ROS) (2016/04/11 - 2016/04/13)
Encontro (Presidente da Comissão Organizadora)
European Cooperation in Science and Technology, Bélgica
2015/09/09 - 2015/09/12 XXXI LIAC meeting on vascular research (2015/09/09 - 2015/09/12)
Conferência (Membro da Comissão Organizadora)
Universidade Lusófona de Humanidades e Tecnologias Centro de Investigação em Biociências e Tecnologias da Saúde, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2017/01/01 - Atual Participation in several public outreach activities (e.g. European Researchers’ Night, public workshops, science dissemination activities in high schools, NutRedOx dissemination video, Social Media)

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2019/03/15 Prostaglandina E2 intracelular, factor inducible por hipoxia y vesículas extracelulares como mediadores de la lesión de células proximales tubulares.
Vogal
Coral García Pastor (Doutoramento)
Universidad de Alcalá de Henares Facultad de Medicina y Ciencias de la Salud, Espanha
2018/04/30 Manganase superoxide dismutase (MnSOD) protects the liver from oxidative damage and cancer
Vogal
Anja Konzack (Doutoramento)
Faculty of Medicine, University of Oulu, Finlândia
2017/12/11 Modelo DPSEEA y vigilancia en salud ambiental en Portugal: enfermedades oncológicas
Arguente principal
Rogério Nunes (Doutoramento)
Universidad de Alcalá de Henares Facultad de Medicina y Ciencias de la Salud, Espanha
2014/07/17 Estudo do potencial de aplicabilidades dos extractos de ginja na promoção da saúde e bem-estar cutâneos
Arguente
Elisabete Maurício (Doutoramento)
Universidad de Alcalá de Henares Facultad de Medicina y Ciencias de la Salud, Espanha

Arbitragem científica em revista

Nome da revista (ISSN) Editora
2020/04/15 - Atual Antioxidants (2076-3921) MDPI AG
2019/01/01 - Atual Current Nutraceuticals (2665-9786) Bentham Science
2018/09/01 - 2019/10/01 Oxidative Medicine and Cellular Longevity (1942-0994) Hindawi Limited
2018/01/01 - 2019 Free Radical Research (1029-2470) Informa UK (Taylor & Francis)

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2017/01/01 - 2017/12/31 Evaluation Panel of the call for Installation Research Projects UIP-05-2017 - Croatian Science Foundation (Hrzz-epp),
Avaliador
Hrvatska Zaklada za Znanost, Croácia Hrvatska Zaklada za Znanost

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2018/12/02 - Atual Applied Toxicology MSc in Health Products and Food Supplements (Mestrado) Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2018/07/01 - Atual Cell Migration Workshop Cell Culture (Curso de doutoramento (conclusão de unidades curriculares)) Universidade de Coimbra Faculdade de Medicina, Portugal
2013/09/01 - Atual Food Toxicology Nutrition Sciences (Licenciatura) Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2013/01/02 - Atual Pharmacology Nutrition Sciences (Licenciatura)
2012/02/02 - Atual Coordination of the Advanced learning training on Fundamentals of Cell Culture; Lecturer of the disciplines: Initiation to Cell Culture; Basic Techniques in Cell Culture; Cytotoxicity, cell viability and proliferation Fundamentals of Cell Culture (Especialização pós-licenciatura) ALIES - Associação Lusófona para o Desenvolvimento da Investigação e Ensino em Ciências de Saúde, Portugal
2012/01/02 - Atual Pharmacology I, Pharmacology II Pharmaceutical Sciences (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2007/07/01 - Atual Toxicology and Pharmacotoxicology Pharmaceutical Sciences (Mestrado integrado) Universidade Lusófona de Humanidades e Tecnologias Escola de Ciências e Tecnologias da Saúde, Portugal
2007/01/01 - Atual Natural and synthetic antioxidants MSc in Food Quality and Health (Mestrado) Universidade de Lisboa Faculdade de Farmácia, Portugal
2019/09/30 - 2019/10/02 Coordinator of the NutRedOx International Training School in Molecular Nutrition. Coordinator and Lecturer of the second workshop of this training school - Cell Migration Workshop: concepts, mechanisms and techniques Molecular Nutrition (Outros) European Cooperation in Science and Technology, Bélgica

Membro de associação

Nome da associação Tipo de participação
2019/01/01 - Atual Society for Free Radical Biology and Medicine Full member
2018/01/01 - Atual Sociedade Portuguesa de Bioquímica Full member
2015/01/01 - Atual Sociedade Portuguesa de Farmacologia Full member
2011/01/01 - Atual Society for Free Radical Research – Europe Full member

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2018/09/01 - Atual National Observatory for Emerging Risks (ASAE, Portuguese Food Safety Authority)
Membro
Autoridade de Segurança Alimentar e Económica, Portugal
2017/09/01 - 2020/09/30 Member of the Management Committee of the COST action CA16112–NutRedOx (National delegate and Science Communication Manager)
Outro
European Cooperation in Science and Technology, Bélgica
2013/09/01 - 2016/09/30 Member of the Management Committee of the COST action BM1203 – EU-ROS (National delegate)
Membro
European Cooperation in Science and Technology, Bélgica

Tutoria

Tópico Nome do aluno
2019/07/01 - 2019/12/31 Cancer Pharmacology Íris Cláudia Felisberto Guerreiro
2019/01/02 - 2019/04/15 Food bioactive and cancer progression Bojana Vidovic
2017/07/01 - 2018/12/31 Cancer Pharmacology Nuno Catalão de Almeida
2015/09/01 - 2015/12/20 Cytotoxicity profile of ruin-loaded nanoparticles Andre Rolim Baby
Distinções

Prémio

2019 Best oral communication at Physioma 2019
Sociedade Portuguesa de Fisiologia, Portugal
2018 Premio Extraordinario de Doctorado (as supervisor)
Universidad de Alcalá de Henares, Espanha
2014 2º Prémio NurnbergMesse Brasil
Congresso Brasileiro de Cosmetologia , Brasil
2014 Best poster award
II Jornadas Ibéricas de Toxicologia, Portugal
2010 Early career investigator prize
Society for Free Radical Research, Noruega

Título

2018 European Registered Toxicologist
EUROTOX, Bélgica

Outra distinção

2012 Homenagem da Sociedade Portuguesa de Senologia
Sociedade Portuguesa de Senologia, Portugal