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Mário Santos. Publicou 57 artigos em revistas especializadas. Possui 2 capítulo(s) de livros.
Identificação

Identificação pessoal

Nome completo
Mário Santos

Nomes de citação

  • Santos, Mário

Identificadores de autor

Ciência ID
CB17-AD56-DE37
ORCID iD
0000-0002-4509-0260

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Clínica - Sistemas Cardíacos e Cardiovasculares

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês
Português (Idioma materno)
Formação
Grau Classificação
2018 - 2020
Em curso
Executive MSc in Health Economics, Outcomes and Management in Cardiovascular Sciences Programme (Mestrado)
Especialização em Health Economics
London School of Economics and Political Science, Reino Unido
2008 - 2016
Concluído
Programa Doutoral em Medicina e Oncologia Molecular (Doutoramento)
Universidade do Porto Faculdade de Medicina, Portugal
2012 - 2014
Concluído
Harvard Medical School Clinical Scholars Research Training (Diploma de especialização)
Harvard Medical School, Estados Unidos
2000 - 2007
Concluído
Medicina (Licenciatura)
Universidade do Porto Faculdade de Medicina, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2013 - 2014 Investigador (Investigação) Brigham and Women's Hospital, Estados Unidos

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2021/01/01 - Atual Professor Associado Convidado (Docente Universitário) Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar, Portugal
2017 - 2019 Professor Auxiliar Convidado (Docente Universitário) Universidade do Porto Faculdade de Medicina, Portugal
2014 - 2016 Assistente Convidado (Docente Universitário) Universidade do Porto Faculdade de Medicina, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2015 - Atual Cardiology Consultant Centro Hospitalar Universitário do Porto EPE, Portugal
2009 - 2015 Cardiology Fellow Centro Hospitalar Universitário do Porto EPE, Portugal
Centre Hospitalier Francois Quesnay Consultation de Cardiologie, França
2010 - 2010 Visiting Fellow MedStar Washington Hospital Center, Estados Unidos
2008 - 2008 General Intern Centro Hospitalar Universitário de São João, Portugal
Projetos

Bolsa

Designação Financiadores
2018 - Atual Clinical and Economic Impact of a Clinic-based versus Home-based Exercise Intervention in Heart Failure with Preserved Ejection Fraction: A Pragmatic Clinical Trial
02/SAICT/2017-30011
Portuguese Foundation of Science and Technology
2013 - 2015 Junior Clinical Research and Career Development Award.
HMSP-ICJ/013/2012
Portuguese Science Foundation
Produções

Publicações

Artigo em revista
  1. Sofia Gonçalves Viamonte; Ana Vieira Joaquim; Alberto Jorge Alves; Eduardo Vilela; Andreia Capela; Cristina Ferreira; Barbara Fresco Duarte; et al. "Cardio-Oncology Rehabilitation for Cancer Survivors With High Cardiovascular Risk". JAMA Cardiology (2023): http://dx.doi.org/10.1001/jamacardio.2023.3558.
    10.1001/jamacardio.2023.3558
  2. Rui Baptista; José Silva Cardoso; Helena Canhão; Ana Maria Rodrigues; Irina Kislaya; Fátima Franco; Ana Filipa Bernardo; et al. "Portuguese Heart Failure Prevalence Observational Study (PORTHOS) rationale and design – A population-based study". Revista Portuguesa de Cardiologia (2023): http://dx.doi.org/10.1016/j.repc.2023.10.004.
    10.1016/j.repc.2023.10.004
  3. Marisol Gouveia; Cristine Schmidt; Priscilla Gois Basilio; Susana S. Aveiro; Pedro Domingues; Ke Xia; Wilfredo Colón; et al. "Exercise training decreases the load and changes the content of circulating SDS-resistant protein aggregates in patients with heart failure with reduced ejection fraction". Molecular and Cellular Biochemistry (2023): http://dx.doi.org/10.1007/s11010-023-04884-z.
    10.1007/s11010-023-04884-z
  4. Cristine Schmidt; Sandra Magalhães; Priscilla Gois Basilio; Marisol Gouveia; Manuel Teixeira; Cláudio Santos; Aida Isabel Tavares; et al. "Home- versus centre-based EXercise InTervention in patients with Heart Failure (EXIT-HF trial): A pragmatic randomized controlled trial". Revista Portuguesa de Cardiologia (2023): https://doi.org/10.1016/j.repc.2023.05.013.
    10.1016/j.repc.2023.05.013
  5. André Alexandre; Inês Furtado; Luísa Carvalho; Fabienne Gonçalves; Alzira Melo; Joana Alves; Mário Santos; Abílio Reis. "Transitioning intravenous epoprostenol to oral selexipag in idiopathic pulmonary arterial hypertension: a case report". ESC Heart Failure (2023): https://doi.org/10.1002/ehf2.14428.
    10.1002/ehf2.14428
  6. stefano coiro; Mathieu Echivard; Dejan Simonovic; Kevin Duarte; Mario Santos; Marina Deljanin-Ilic; Masatake Kobayashi; Giuseppe Ambrosio; Nicolas Girerd. "Exercise-induced B-lines for the diagnosis of heart failure with preserved ejection fraction: a two-centre study". Clinical Research in Cardiology (2023): http://dx.doi.org/10.1007/s00392-023-02219-y.
    10.1007/s00392-023-02219-y
  7. Suiane Cavalcante; Sofia Viamonte; Rui S. Cadilha; Ilda Ribeiro; Ana Cristina Gonçalves; Joao Venancio; Marisol Gouveia; et al. "Maximal Exercise Improves the Levels of Endothelial Progenitor Cells in Heart Failure Patients". Current Issues in Molecular Biology 45 3 (2023): 1950-1960. http://dx.doi.org/10.3390/cimb45030125.
    10.3390/cimb45030125
  8. Viamonte, Sofia Gonçalves; Joaquim, Ana; Alves, Alberto; Vilela, Eduardo; Capela, Andreia; Ferreira, Cristina; Costa, Ana João; et al. "Adherence, safety, and satisfaction of a cardio-oncology rehabilitation program framework versus community exercise training for cancer survivors: findings from the CORE trial". Supportive Care in Cancer 31 3 (2023): http://dx.doi.org/10.1007/s00520-023-07638-1.
    10.1007/s00520-023-07638-1
  9. Daniel Caldeira; Hélder Dores; Fátima Franco; Sérgio Bravo Baptista; Sofia Cabral; Maria do Carmo Cachulo; António Peixeiro; et al. "Global warming and heat waves risks for cardiovascular diseases: a position paper of the Portuguese Society of Cardiology". Revista Portuguesa de Cardiologia (2023): http://dx.doi.org/10.1016/j.repc.2023.02.002.
    10.1016/j.repc.2023.02.002
  10. Gouveia, Marisol; Teixeira, Manuel; Schmidt, Cristine; Lopes, Mário; Trindade, Dário; Magalhães, Sandra; Henriques, Ana Gabriela; et al. "Impaired Extracellular Proteostasis in Patients with Heart Failure". Archives of Medical Research (2023): http://dx.doi.org/10.1016/j.arcmed.2023.02.001.
    10.1016/j.arcmed.2023.02.001
  11. Filipe Morais; Rita Nogueira-Ferreira; Hugo Rocha; José A. Duarte; Laura Vilarinho; Ana F. Silva; Adelino Leite-Moreira; et al. "Exercise training counteracts the cardiac metabolic remodelling induced by experimental pulmonary arterial hypertension". Archives of Biochemistry and Biophysics (2022): https://doi.org/10.1016/j.abb.2022.109419.
    10.1016/j.abb.2022.109419
  12. Marisol Gouveia; Cristine Schmidt; Manuel Teixeira; Mário Lopes; Susana S. Aveiro; Pedro Domingues; Ke Xia; et al. "Characterization of Plasma SDS-Protein Aggregation Profile of Patients with Heart Failure with Preserved Ejection Fraction". Journal of Cardiovascular Translational Research (2022): http://dx.doi.org/10.1007/s12265-022-10334-w.
    10.1007/s12265-022-10334-w
  13. Mario Santos. "Clinical Determinants and Barriers to Cardiac Rehabilitation Enrollment of Patients with Heart Failure with Reduced Ejection Fraction: A Single-Center Study in Portugal". Journal of Cardiovascular Development and Disease 9 10 (2022): 344-344. http://dx.doi.org/10.3390/jcdd9100344.
    10.3390/jcdd9100344
  14. Mario Santos. "Impact of a COmprehensive cardiac REhabilitation framework among high cardiovascular risk cancer survivors: Protocol for the CORE trial". International Journal of Cardiology (2022): http://dx.doi.org/10.1016/j.ijcard.2022.09.075.
    10.1016/j.ijcard.2022.09.075
  15. Mario Santos. "A Not So Innocent Murmur". Heart, Lung and Circulation (2022): http://dx.doi.org/10.1016/j.hlc.2022.04.055.
    10.1016/j.hlc.2022.04.055
  16. Mario Santos. "Nets, pulmonary arterial hypertension, and thrombo-inflammation". Journal of Molecular Medicine 100 5 (2022): 713-722. http://dx.doi.org/10.1007/s00109-022-02197-0.
    10.1007/s00109-022-02197-0
  17. Mario Santos. "Reduced Levels of Circulating Endothelial Cells and Endothelial Progenitor Cells in Patients with Heart Failure with Reduced Ejection Fraction". Archives of Medical Research 53 3 (2022): 289-295. http://dx.doi.org/10.1016/j.arcmed.2022.02.001.
    10.1016/j.arcmed.2022.02.001
  18. Mario Santos. "Physical activity and its clinical correlates in chronic thromboembolic pulmonary hypertension". Pulmonary Circulation 12 2 (2022): http://dx.doi.org/10.1002/pul2.12048.
    10.1002/pul2.12048
  19. Gouveia, Marisol; Teixeira, Manuel; Schmidt, Cristine; Magalhães, Sandra; Nunes, Alexandra; Santos, Mário; Vieira, Sandra; Ribeiro, Fernando. "EXERCISE TRAINING INCREASES TOXIC PROTEIN OLIGOMERS UPTAKE FUNCTION OF PERIPHERAL BLOOD MONONUCLEAR CELLS IN PATIENTS WITH HEART FAILURE". Journal of the American College of Cardiology 79 9 (2022): 1442. http://dx.doi.org/10.1016/s0735-1097(22)02433-0.
    10.1016/s0735-1097(22)02433-0
  20. Gouveia, Marisol; Martins, Tânia; Schmidt, Cristine; Gois, Priscilla; Teixeira, Manuel; Muñoz, Xavier; Ximénez-Embún, Pilar; et al. "EXERCISE TRAINING IMPROVES THE EXOSOMAL CONTENT IN PATIENTS WITH HEART FAILURE". Journal of the American College of Cardiology 79 9 (2022): 1591. http://dx.doi.org/10.1016/s0735-1097(22)02582-7.
    10.1016/s0735-1097(22)02582-7
  21. "Heart Failure Incidence Following ST-Elevation Myocardial Infarction". The American Journal of Cardiology 164 (2022): 14-20. http://dx.doi.org/10.1016/j.amjcard.2021.10.035.
    10.1016/j.amjcard.2021.10.035
  22. Marta Fontes Oliveira; Ana Leonor Rei; Maria Isilda Oliveira; Isabel Almeida; Mário Santos. "Prevalence and prognostic significance of heart failure with preserved ejection fraction in systemic sclerosis". Future Cardiology 18 1 (2022): 17-25. https://doi.org/10.2217/fca-2020-0238.
    10.2217/fca-2020-0238
  23. "Histological and haemodynamic characterization of right ventricle in sedentary and trained rats with heart failure with preserved ejection fraction". Experimental Physiology 106 12 (2021): 2457-2471. http://dx.doi.org/10.1113/ep089516.
    10.1113/ep089516
  24. "Sexual dimorphism in cardiac remodeling: the molecular mechanisms ruled by sex hormones in the heart". Journal of Molecular Medicine (2021): http://dx.doi.org/10.1007/s00109-021-02169-w.
    10.1007/s00109-021-02169-w
  25. Marta Fontes Oliveira; Maria Isilda Oliveira; Inês Furtado; Luísa Carvalho; Fabienne Gonçalves; Abílio Reis; Mário Santos. "External validation of different clinical and echocardiographic scores to distinguish post- from precapillary pulmonary hypertension". Echocardiography 38 9 (2021): 1558-1566. https://doi.org/10.1111/echo.15172.
    10.1111/echo.15172
  26. "An update of the molecular mechanisms underlying doxorubicin plus trastuzumab induced cardiotoxicity". Life Sciences 280 (2021): 119760-119760. http://dx.doi.org/10.1016/j.lfs.2021.119760.
    10.1016/j.lfs.2021.119760
  27. "Platypnoea-orthodeoxia syndrome: the importance of the patient’s posture for diagnosis". BMJ Case Reports 14 6 (2021): e243210-e243210. http://dx.doi.org/10.1136/bcr-2021-243210.
    10.1136/bcr-2021-243210
  28. Santos, Mário. "Standardized exercise training is feasible, safe, and effective in pulmonary arterial and chronic thromboembolic pulmonary hypertension: results from a large European multicentre randomized controlled trial.". European heart journal (2020): https://doi.org/10.1093/eurheartj/ehaa696.
    10.1093/eurheartj/ehaa696
  29. Santos, Mário. "Pulmonary vascular dysfunction among people aged over 65 years in the community in the Atherosclerosis Risk In Communities (ARIC) Study: A cross-sectional analysis". PLOS Medicine 17 10 (2020): e1003361-e1003361. http://dx.doi.org/10.1371/journal.pmed.1003361.
    10.1371/journal.pmed.1003361
  30. Santos, Mário. "Risk assessment of acute pulmonary embolism utilizing coronary artery calcifications in patients that have undergone CT pulmonary angiography and transthoracic echocardiography". European Radiology (2020): http://dx.doi.org/10.1007/s00330-020-07385-5.
    10.1007/s00330-020-07385-5
  31. Fontes Oliveira, Marta; Costa, Ricardo; Frias, André; Santos, Raquel; Brochado, Bruno; Santos, Mário; Silveira, João; et al. "Pre-infarction angina is associated with improved prognosis in diabetic patients with ST-elevation myocardial infarction ¿ data from a contemporary cohort". Coronary Artery Disease Publish Ah (2020): http://dx.doi.org/10.1097/mca.0000000000000968.
    10.1097/mca.0000000000000968
  32. Santos, Mário. "Exercise preconditioning prevents left ventricular dysfunction and remodeling in monocrotaline-induced pulmonary hypertension". Porto Biomedical Journal 5 5 (2020): e081-e081. http://dx.doi.org/10.1097/j.pbj.0000000000000081.
    10.1097/j.pbj.0000000000000081
  33. Santos, Mário. "[Exercise-based cardiac rehabilitation in COVID-19 times: one small step for health care systems, one giant leap for patients].". Revista espanola de cardiologia (2020): https://europepmc.org/articles/PMC7455143.
    10.1016/j.recesp.2020.06.040
  34. Santos, Mário. "Cardiac rehabilitation programs for heart failure patients in the time of COVID-19.". Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology (2020): https://europepmc.org/articles/PMC7318965.
    10.1016/j.repc.2020.06.012
  35. Schmidt, Cristine; Santos, Mário; Bohn, Lucimere; Delgado, Bruno; Moreira-Gonçalves, Daniel; ADELINO F. LEITE-MOREIRA; Oliveira, José. "Dynamic balance and mobility explains quality of life in HFpEF, outperforming all the other components of physical fitness". Arquivos Brasileiros de Cardiologia 114 4 (2020): 701-707. http://publicacoes.cardiol.br/portal/abc/ingles/2020/v11404/pdf/i11404022.pdf.
    Aceite para publicação
  36. Santos, Mário. "Equilíbrio Dinâmico e Mobilidade Explicam a Qualidade de Vida na ICFEP, Superando Todos os Outros Componentes da Aptidão Física". Arquivos Brasileiros de Cardiologia 114 4 (2020): 701-707. http://dx.doi.org/10.36660/abc.20190080.
    10.36660/abc.20190080
  37. Santos, Mário. "Association of pulmonary hypertension and right ventricular function with exercise capacity in heart failure". ESC Heart Failure (2020): http://dx.doi.org/10.1002/ehf2.12717.
    10.1002/ehf2.12717
  38. Santos, Mário. "Physical activity and exercise training in heart failure with preserved ejection fraction: gathering evidence from clinical and pre-clinical studies". Heart Failure Reviews (2020): http://dx.doi.org/10.1007/s10741-020-09973-5.
    10.1007/s10741-020-09973-5
  39. Santos, Mário. "Glittre Activities Daily Living Test: Physiological responses in patients with heart failure". European Journal of Preventive Cardiology (2020): http://dx.doi.org/10.1177/2047487320911173.
    10.1177/2047487320911173
  40. Santos, Mário. "Predictors of In-Hospital Mortality after Recovered Out-of-Hospital Cardiac Arrest in Patients with Proven Significant Coronary Artery Disease: A Retrospective Study". The Journal of Critical Care Medicine (2020): http://dx.doi.org/10.2478/jccm-2020-0006.
    10.2478/jccm-2020-0006
  41. Santos, Mário. "Comparison of questionnaire and accelerometer-based assessments of physical activity in patients with heart failure with preserved ejection fraction: clinical and prognostic implications". Scandinavian Cardiovascular Journal (2020): http://dx.doi.org/10.1080/14017431.2019.1707863.
    10.1080/14017431.2019.1707863
  42. Santos, Mário. "Echocardiographic Assessment of Right Ventriculo-arterial Coupling: Clinical Correlates and Prognostic Impact in Heart Failure Patients Undergoing Cardiac Resynchronization Therapy". Journal of Cardiovascular Imaging (2020): http://dx.doi.org/10.4250/jcvi.2019.0094.
    10.4250/jcvi.2019.0094
  43. Santos, Mário. "Effects of exercise on endothelial progenitor cells in patients with cardiovascular disease: A systematic review and meta-analysis of randomized controlled trials". Revista Portuguesa de Cardiologia (2019): http://dx.doi.org/10.1016/j.repc.2019.02.016.
    10.1016/j.repc.2019.02.016
  44. Santos, Mário. "Unexplained exertional intolerance associated with impaired systemic oxygen extraction". European Journal of Applied Physiology (2019): http://dx.doi.org/10.1007/s00421-019-04222-6.
    10.1007/s00421-019-04222-6
  45. Santos, Mário. "Association of Undifferentiated Dyspnea in Late Life With Cardiovascular and Noncardiovascular Dysfunction". JAMA Network Open (2019): http://dx.doi.org/10.1001/jamanetworkopen.2019.5321.
    10.1001/jamanetworkopen.2019.5321
  46. Abílio Reis; Mário Santos; Inês Furtado; Célia Cruz; Pedro Sa-Couto; Alexandra Queirós; Luís Almeida; Nelson Rocha. "Disability and its clinical correlates in pulmonary hypertension measured through the World Health Organization Disability Assessment Schedule 2.0: a prospective, observational study". Jornal Brasileiro de Pneumologia 45 4 (2019): https://doi.org/10.1590/1806-3713/e20170355.
    10.1590/1806-3713/e20170355
  47. Santos, Mário. "ERS statement on exercise training and rehabilitation in patients with severe chronic pulmonary hypertension". European Respiratory Journal (2019): http://dx.doi.org/10.1183/13993003.00332-2018.
    10.1183/13993003.00332-2018
  48. Santos, Mário. "Cardiovascular phenotype and prognosis of patients with heart failure induced by cancer therapy". Heart (2019): http://dx.doi.org/10.1136/heartjnl-2018-313234.
    10.1136/heartjnl-2018-313234
  49. Santos, Mário. "Resting Heart Rate and Chronotropic Response to Exercise: Prognostic Implications in Heart Failure Across the Left Ventricular Ejection Fraction Spectrum". Journal of Cardiac Failure (2018): http://dx.doi.org/10.1016/j.cardfail.2018.09.015.
    10.1016/j.cardfail.2018.09.015
  50. Santos, Mário. "Long-term survival in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: Insights from a referral center in Portugal". Revista Portuguesa de Cardiologia (2018): http://dx.doi.org/10.1016/j.repc.2018.02.009.
    10.1016/j.repc.2018.02.009
  51. Santos, Mário. "Pulmonary hypertension: Real-world data from a Portuguese expert referral centre". Pulmonology (2018): http://dx.doi.org/10.1016/j.pulmoe.2018.02.003.
    10.1016/j.pulmoe.2018.02.003
  52. Santos, Mário. "Mechanisms underlying the impact of exercise training in pulmonary arterial hypertension". Respiratory Medicine (2018): http://dx.doi.org/10.1016/j.rmed.2017.11.022.
    10.1016/j.rmed.2017.11.022
  53. Santos, Mário. "Health-Related Quality of Life in Pulmonary Hypertension and Its Clinical Correlates: A Cross-Sectional Study". BioMed Research International (2018): http://dx.doi.org/10.1155/2018/3924517.
    10.1155/2018/3924517
  54. Santos, Mário. "Prognostic Value of Cardiopulmonary Exercise Testing in Heart Failure With Reduced, Midrange, and Preserved Ejection Fraction". Journal of the American Heart Association (2017): http://dx.doi.org/10.1161/jaha.117.006000.
    10.1161/jaha.117.006000
  55. Santos, Mário. "Manual thrombectomy efficiency in relationship to the area at risk in patients with myocardial infarction with TIMI 0-1 coronary flow: Insights from an all comers registry". Catheterization and Cardiovascular Interventions (2017): http://dx.doi.org/10.1002/ccd.26959.
    10.1002/ccd.26959
  56. Santos, Mário. "Functional impact of exercise pulmonary hypertension in patients with borderline resting pulmonary arterial pressure". Pulmonary Circulation (2017): http://dx.doi.org/10.1177/2045893217709025.
    10.1177/2045893217709025
  57. Santos, Mário. "Accuracy of Echocardiography to Estimate Pulmonary Artery Pressures With Exercise". Circulation: Cardiovascular Imaging (2017): http://dx.doi.org/10.1161/circimaging.116.005711.
    10.1161/circimaging.116.005711
  58. Santos, Mário. "Soluble TNF-related apoptosis induced ligand (sTRAIL) is augmented by Post-Conditioning and correlates to infarct size and left ventricle dysfunction in STEMI patients: a substudy from a randomized clinical trial". Heart and Vessels (2017): http://dx.doi.org/10.1007/s00380-016-0851-9.
    10.1007/s00380-016-0851-9
  59. Santos, Mário. "Left ventricular deformation at rest predicts exercise-induced elevation in pulmonary artery wedge pressure in patients with unexplained dyspnoea". European Journal of Heart Failure (2017): http://dx.doi.org/10.1002/ejhf.659.
    10.1002/ejhf.659
  60. Santos, Mário. "Prognostic Importance of Dyspnea for Cardiovascular Outcomes and Mortality in Persons without Prevalent Cardiopulmonary Disease: The Atherosclerosis Risk in Communities Study". PLOS ONE (2016): http://dx.doi.org/10.1371/journal.pone.0165111.
    10.1371/journal.pone.0165111
  61. Ferreira JP; Girerd N; Medeiros PB; Santos M; Carvalho HC; Bettencourt P; Kénizou D; et al. "Spot urine sodium excretion as prognostic marker in acutely decompensated heart failure: the spironolactone effect.". (2016): http://europepmc.org/abstract/med/26615605.
    10.1007/s00392-015-0945-x
  62. Luz A; Santos M; Magalhães R; Oliveira JC; Pacheco A; Silveira J; Cabral S; et al. "Soluble TNF-related apoptosis induced ligand (sTRAIL) is augmented by Post-Conditioning and correlates to infarct size and left ventricle dysfunction in STEMI patients: a substudy from a randomized clinical trial.". (2016): http://europepmc.org/abstract/med/27230030.
  63. Rodrigues P; Sousa MJ; Caiado L; Cabral S; Meireles A; Santos M; Palma P; Torres S. "Intracardiac thrombus and Murphy's law: Reflections on a clinical dilemma.". (2016): http://europepmc.org/abstract/med/26992742.
    10.1016/j.repc.2015.09.027
  64. Santos, Mário. "Heart Failure and Midrange Ejection Fraction". Circulation: Heart Failure (2016): http://dx.doi.org/10.1161/circheartfailure.115.002826.
    10.1161/circheartfailure.115.002826
  65. Moreira-Gonçalves D; Ferreira R; Fonseca H; Padrão AI; Moreno N; Silva AF; Vasques-Nóvoa F; et al. "Cardioprotective effects of early and late aerobic exercise training in experimental pulmonary arterial hypertension.". (2015): http://europepmc.org/abstract/med/26463598.
    10.1007/s00395-015-0514-5
  66. Luz A; Santos M; Magalhães R; Silveira J; Cabral S; Dias V; Oliveira F; et al. "Lack of Benefit of Ischemic Postconditioning After Routine Thrombus Aspiration During Reperfusion: Immediate and Midterm Results.". (2015): http://europepmc.org/abstract/med/25818931.
    10.1177/1074248415578171
  67. Rodrigues P; Cabral S; Santos M; Sousa MJ; Brochado B; Palma P; Torres S. "A revealing murmur.". (2015): http://europepmc.org/abstract/med/26184745.
    10.1007/s12574-015-0248-2
  68. Santos M; Rivero J; McCullough SD; West E; Opotowsky AR; Waxman AB; Systrom DM; Shah AM. "E/e' Ratio in Patients With Unexplained Dyspnea: Lack of Accuracy in Estimating Left Ventricular Filling Pressure.". (2015): http://europepmc.org/abstract/med/26067855.
    10.1161/circheartfailure.115.002161
  69. Santos M; Opotowsky AR; Shah AM; Tracy J; Waxman AB; Systrom DM. "Central cardiac limit to aerobic capacity in patients with exertional pulmonary venous hypertension: implications for heart failure with preserved ejection fraction.". (2015): http://europepmc.org/abstract/med/25550438.
    10.1161/circheartfailure.114.001551
  70. Ferreira JP; Santos M; Oliveira JC; Marques I; Bettencourt P; Carvalho H. "Influence of Spironolactone on Matrix Metalloproteinase-2 in Acute Decompensated Heart Failure.". (2015): http://europepmc.org/abstract/med/25626766.
    10.5935/abc.20140205
  71. Rodrigues P; Santos M; Sousa MJ; Brochado B; Anjo D; Barreira A; Preza-Fernandes J; et al. "Cardiac Rehabilitation after an Acute Coronary Syndrome: The Impact in Elderly Patients.". (2015): http://europepmc.org/abstract/med/25968103.
    10.1159/000381824
  72. Ferreira JP; Santos M. "Heart failure and atrial fibrillation: from basic science to clinical practice.". (2015): http://europepmc.org/abstract/med/25647414.
    10.3390/ijms16023133
  73. Santos M; Systrom D; Epstein SE; John A; Ruiz G; Landzberg MJ; Opotowsky AR. "Impaired exercise capacity following atrial septal defect closure: an invasive study of the right heart and pulmonary circulation.". (2014): http://europepmc.org/abstract/med/25610599.
    10.1086/678509
  74. Luz A; Rodrigues P; Sousa MJ; Silveira I; Anjo D; Brochado B; Santos M; et al. "Thrombus aspiration for reperfusion in myocardial infarction: Predictors and clinical impact of ineffectiveness.". (2014): http://europepmc.org/abstract/med/25481777.
    10.1016/j.repc.2014.05.002
  75. Rodrigues P; Santos M; Marinho A; Cabral S; Vieira M; Reis H; Palma P; Torres S. "Facing the challenges of ventricular hypertrophy: the eyes don't lie.". (2014): http://europepmc.org/abstract/med/25282716.
    10.1016/j.repc.2014.03.011
  76. Luz A; Santos M; Rodrigues P; Sousa MJ; Anjo D; Silveira I; Brochado B; et al. "Preinfarction angina: clinical significance and relationship with total ischemic time in patients with ST-elevation myocardial infarction.". (2014): http://europepmc.org/abstract/med/25089927.
    10.1097/MCA.0000000000000160
  77. Santos M; Shah AM. "Alterations in cardiac structure and function in hypertension.". (2014): http://europepmc.org/abstract/med/24639061.
    10.1007/s11906-014-0428-x
  78. Ferreira JP; Santos M; Almeida S; Marques I; Bettencourt P; Carvalho H. "The role of albuminuria as a non-invasive marker for congestive acutely decompensated chronic heart failure and the spironolactone effect in elderly Portuguese: a non-randomized trial.". (2014): http://europepmc.org/abstract/med/24533733.
    10.1111/nep.12188
  79. Santos M; Leite-Moreira AF. "Effect of ivabradine on heart failure with preserved ejection fraction.". (2014): http://europepmc.org/abstract/med/24269357.
    10.1016/j.jacc.2013.09.064
  80. Sousa-Pinto B; Ferreira-Pinto MJ; Santos M; Leite-Moreira AF. "Central nervous system circuits modified in heart failure: pathophysiology and therapeutic implications.". (2014): http://europepmc.org/abstract/med/24573960.
    10.1007/s10741-014-9427-x
  81. Anjo D; Santos M; Rodrigues P; Brochado B; Sousa MJ; Barreira A; Viamonte S; et al. "The benefits of cardiac rehabilitation in coronary heart disease: a gender issue?". (2014): http://europepmc.org/abstract/med/24507586.
    10.1016/j.repc.2013.06.014
  82. Opotowsky AR; Santos M; Maron BA; Afilalo J; Waxman AB; Landzberg MJ; Forfia PR. "Towards widespread noninvasive assessment of pulmonary vascular resistance in clinical practice.". (2014): http://europepmc.org/abstract/med/24280251.
    10.1016/j.echo.2013.10.010
  83. Ferreira JP; Santos M; Almeida S; Marques I; Bettencourt P; Carvalho H. "Mineralocorticoid receptor antagonism in acutely decompensated chronic heart failure.". (2014): http://europepmc.org/abstract/med/24070521.
    10.1016/j.ejim.2013.08.711
  84. Santos M; Reis A; Gonçalves F; Ferreira-Pinto MJ; Cabral S; Torres S; Leite-Moreira AF; Henriques-Coelho T. "Adiponectin levels are elevated in patients with pulmonary arterial hypertension.". (2014): http://europepmc.org/abstract/med/24114971.
    10.1002/clc.22210
  85. Ferreira JP; Santos M; Almeida S; Marques I; Bettencourt P; Carvalho H. "High-sensitivity troponin T: a biomarker for diuretic response in decompensated heart failure patients.". (2014): http://europepmc.org/abstract/med/25247106.
    10.1155/2014/269604
  86. Santos M; Pinheiro-Vieira A; Hipólito-Reis A. "Bradycardia in the athlete: don't always blame the autonomic system!". (2013): http://europepmc.org/abstract/med/23933847.
    10.1093/europace/eut238
  87. Ferreira JP; Santos M; Almeida S; Marques I; Bettencourt P; Carvalho H. "Tailoring diuretic therapy in acute heart failure: insight into early diuretic response predictors.". (2013): http://europepmc.org/abstract/med/23839288.
    10.1007/s00392-013-0588-8
  88. Santos M; Carvalho H. "Renal sympathetic denervation in resistant hypertension.". (2013): http://europepmc.org/abstract/med/23675555.
    10.4330/wjc.v5.i4.94
  89. Vieira MS; Luz A; Anjo D; Antunes N; Santos M; Carvalho H; Torres S. "Triple, simultaneous, very late coronary stent thrombosis.". (2013): http://europepmc.org/abstract/med/23465386.
    10.1016/j.repc.2012.06.019
  90. Antunes N; Meireles A; Gomes C; Vieira M; Anjo D; Santos M; Vieira P; et al. "[Anomalous origin of the right coronary artery and acute myocardial infarction: cause or coincidence?].". (2012): http://europepmc.org/abstract/med/22717294.
    10.1016/j.repc.2011.11.013
  91. Santos M; Dias V; Meireles A; Gomes C; Luz A; Mendes D; Caiado L; et al. "Hyponatremia--an unusual trigger of Takotsubo cardiomyopathy.". (2011): http://europepmc.org/abstract/med/22030327.
    10.1016/j.repc.2011.09.006
  92. Santos M; Luz A; Silveira J; Antunes N; Vieira M; Anjo D; Rodrigues P; et al. "Aortocoronary dissection complicating percutaneous angioplasty.". (2011): http://europepmc.org/abstract/med/21959001.
    10.1016/S0870-2551(11)70020-8
  93. Dias V; Cabral S; Vieira M; Sá I; Anjo D; Gomes C; Meireles A; et al. "Noncompaction cardiomyopathy and multiple coronary arterioventricular fistulae: 1 or 2 distinct disease entities?". (2011): http://europepmc.org/abstract/med/21679847.
    10.1016/j.jacc.2010.10.066
  94. Santos M; Henriques-Coelho T; Leite-Moreira A. "Immunomodulatory role of thymulin in lung diseases.". (2010): http://europepmc.org/abstract/med/20055713.
    10.1517/14728220903512991
  95. Henriques-Coelho T; Oliveira SM; Moura RS; Roncon-Albuquerque R Jr; Neves AL; Santos M; Nogueira-Silva C; et al. "Thymulin inhibits monocrotaline-induced pulmonary hypertension modulating interleukin-6 expression and suppressing p38 pathway.". (2008): http://europepmc.org/abstract/med/18511508.
    10.1210/en.2008-0018
Capítulo de livro
  1. Nogueira-Ferreira, Rita; Moreira-Gonçalves, Daniel; Santos, Mário; Leite-Moreira, Adelino; Lira, Fabio Santos; Ferreira, Rita. "Glucose utilization by the trained heart: the molecular mechanisms behind fuel choice". In Glycolysis, editado por Ferreira, Rita; Fontes Oliveira, Pedro; Nogueira-Ferreira, Rita, 75-90. Elsevier, 2024.
    10.1016/b978-0-323-91704-9.00015-x
  2. Manuel Teixeira; Tânia Soares Martins; Marisol Gouveia; Ana Gabriela Henriques; Mário Santos; Fernando Ribeiro. "Effects of Exercise on Circulating Extracellular Vesicles in Cardiovascular Disease". 2023.
    10.1007/978-981-99-1443-2_16
  3. Santos, Mário. "Stress Echocardiography and Echo in Cardiopulmonary Testing". 2019.
    10.1016/b978-0-323-39226-6.00027-8
  4. Santos, Mário. "Exercise Training in Pulmonary Hypertension and Right Heart Failure: Insights from Pre-clinical Studies". 2017.
    10.1007/978-981-10-4307-9_17
Poster em conferência
  1. Teixeira, Manuel; Nogueira-Ferreira, Rita; Oliveira, Maria Isilda; Gouveia, Marisol; Ferreira, Rita; Santos, Mário; Ribeiro, Fernando. "Extracellular vesicles proteomic profile of patients with idiopathic pulmonary arterial hypertension". Trabalho apresentado em VI iBiMED symposium, 2023.
  2. Morais, Filipe; Nogueira-Ferreira, Rita; Rocha, Hugo; Duarte, José Alberto ; Vilarinho, Laura; Silva, Ana Filipa; Leite-Moreira, Adelino; et al. "Impact of exercise training on cardiac metabolic remodelling in a pulmonary arterial hypertension animal model". Trabalho apresentado em 1st Conference of the Doctoral Program in Metabolism ¿ Clinical and Experimental Diabesity: looking by a different prism, 2022.
  3. Gouveia, Marisol; Schmidt, Cristine; Teixeira, Manuel; Lopes, Mário; Aveiro, Susana; Domingues, Pedro; Xia, Ke; et al. "Increased levels of circulating SDS-resistant protein aggregates in patients with heart failure with preserved ejection fraction". Trabalho apresentado em Heart Failure & World Congress on Acute Heart Failure, 2022.
  4. Ferreira, Cláudia; Santos, Mário; Ferreira, Rita; Schmidt, Cristine; Barros, António; Vasques-Nóvoa, Francisco; Leite-Moreira, Adelino; Amado, Francisco; Nogueira-Ferreira, Rita. "Urine proteomics to study sex-related differences in heart failure". Trabalho apresentado em XIII Encontro Nacional de Estudantes de Bioquímica, 2021.
  5. Schmidt, Cristine; Santos, Mário; Bohn, Lucimere; Delgado, Bruno Miguel; Moreira-Goncalves , Daniel; Leite-Ferreira, Adelino; Oliveira, José; et al. "Dynamic balance and mobility is the physical fitness component that better predicts quality of life in HFpEF patients". Trabalho apresentado em EuroPrevent 2019, 2019.
  6. Schmidt, Cristine; Santos, Mário; Bohn, Lucimere; Moreira-Gonçalves, Daniel; Leite-Ferreira, Adelino; Oliveira, José. "Validity of self-reported against accelerometer derived physical activity levels in patients with heart failure with preserved ejection fraction". Trabalho apresentado em I Novel Therapeutic Strategies for Noncommunicable Diseases, 2018.
  7. Schmidt, Cristine; Bohn, Lucimere; Santos, Mário; Moreira-Gonçaves, Daniel; Oliveira, José. "Subjective and objective levels of physical activity in patients with heart failure with preserved ejection fraction". Trabalho apresentado em 23rd Annual Congress of the European College of Sport Science, 2018.
  8. Schmidt, Cristine; Bohn, Lucimere; Santos, Mário; Moreira-Gonçalves, Daniel; Oliveira, Jose. "Comparison of self-reported and accelerometer-assessed physical activity and sedentary time in patients with heart failure with preserved ejection fraction". Trabalho apresentado em Heart Failure 2018, 2018.
Resumo em conferência
  1. Gouveia, Marisol; Soares Martins, T; Schmidt, Cristine; Gois, Priscilla; Teixeira, Manuel; Munoz, Xavier; Embun, Pillar Ximenez; et al. "Exercise Training Improves the exosomal content in patients with heart failure. Conference abstract published on Journal of the American College of Cardiology". Trabalho apresentado em 2022 American College of Cardiology, Washington, 2022.
    Publicado
  2. Gouveia, Marisol; Schmidt, Cristine; Teixeira, Manuel; Magalhães, Sandra; Nunes, Alexandra; Lopes, Mário; Ferreira, Rita; et al. "ANALYSIS OF PLASMA PROTEIN AGGREGATION FROM PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION". 2021.
  3. Priscilla Gois Basílio; Ribeiro, Fernando; Sandra Magalhães; Schmidt, Cristine; Ana Barreira; Preza Fernande; Santos, Mário. "Comparação de um programa de reabilitação cardíaca domiciliar versus hospitalar na composição corporal e aptidão cardiorrespiratória em indivíduos com insuficiência cardíaca". Trabalho apresentado em 24 Congresso Português de Obesidade, Virtual, 2020.
    Publicado
  4. Schmidt, Cristine; Bovolini, José António; Gonçalves, Nádia; Vasques-Novoa, Francisco; Santos, Mário; Leite-Moreira, Adelino; Henriques-Coelho, Tiago; Duarte, José Alberto; Moreira-Gonçalves, Daniel. "Protective effects of exercise training against left ventricular dysfunction and remodeling in experimental pulmonary arterial hypertension.". Trabalho apresentado em Heart Failure 2018, Viena, 2018.
Atividades

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2021/06/01 - Atual COMPARISON OF DIFFERENT PHYSIOLOGICAL PARAMETERS IN EXERCISE TRAINING INTENSITY PRESCRIPTION IN HEART FAILURE
Orientador
2020/01/01 - Atual Impact of a COmprehensive cardiac REhabilitation framework among high cardiovascular risk cancer survivors: rationale and study design of the CORE trial.
Coorientador
2020 - Atual Targeting pulmonary artery endothelial cells dysfunction in pulmonary arterial hypertension: in situ assessment of the effects of acute exercise.
Coorientador
2019/01/01 - Atual The impact of hospital-based and home-based cardiac rehabilitation exercise capacity of patients with heart failure and implanted cardiac devices: a randomized clinical trial
Orientador
2018/01/01 - Atual O EXERCÍCIO FÍSICO NA DOENÇA ARTERIAL PERIFÉRICA: IMPACTO CLÍNICO E MECANISMOS FISIOPATOLÓGICOS SUBJACENTES.
Coorientador
2017 - Atual Analysis of protein aggregation in plasma of patients with heart failure with preserved ejection fraction to find novel therapeutic targets and monitor therapeutic interventions.
Coorientador
2019/06/01 - 2021/06/01 Assessment of cardiovascular secondary prevention in post-acute myocardial infarction patients: clinical correlates and prognostic significance.
Orientador
2018/06/01 - 2020/06/01 Prevalence, clinical correlates and prognostic significance of heart failure with preserved ejection fraction in systemic sclerosis.
Orientador
2017/06/01 - 2019/06/01 Daily life physical activity in Patients with Chronic Thromboembolic Pulmonary Hypertension.
Orientador
2016/06/01 - 2018/06/01 Clinical correlats and prognostic impact of right ventriculo-arterial coupling in patients with heart failure undergoing cardiac resynchronization therapy.
Orientador
2013/06/01 - 2015/06/01 Prognostic value of cardiac rehabilitation response in coronary artery disease
Orientador