| Artigo em revista |
- Costello, Lydia; Dicolandrea, Teresa; Tasseff, Ryan; Isfort, Robert; Bascom, Charlie; von Zglinicki, Thomas; Przyborski, Stefan.
"Tissue engineering strategies to bioengineer the ageing skin phenotype in vitro". Aging Cell 21 2 (2022): http://dx.doi.org/10.1111/acel.13550.
10.1111/acel.13550
- Low, Evon; Alimohammadiha, Ghazaleh; Smith, Lucy A.; Costello, Lydia F.; Przyborski, Stefan A.; von Zglinicki, Thomas; Miwa,
Satomi. "How good is the evidence that cellular senescence causes skin ageing?". Ageing Research Reviews 71 (2021):
101456. http://dx.doi.org/10.1016/j.arr.2021.101456.
10.1016/j.arr.2021.101456
- Lagnado, Anthony; Leslie, Jack; Ruchaud-Sparagano, Marie-Helene; Victorelli, Stella; Hirsova, Petra; Ogrodnik, Mikolaj; Collins,
Amy L; et al. "Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner". The EMBO Journal
40 9 (2021): http://dx.doi.org/10.15252/embj.2020106048.
10.15252/embj.2020106048
- von Zglinicki, Thomas; Wan, Tengfei; Miwa, Satomi. "Senescence in Post-Mitotic Cells: A Driver of Aging?". Antioxidants
& Redox Signaling 34 4 (2021): 308-323. http://dx.doi.org/10.1089/ars.2020.8048.
10.1089/ars.2020.8048
- Ogrodnik, Mikolaj; Evans, Shane A.; Fielder, Edward; Victorelli, Stella; Kruger, Patrick; Salmonowicz, Hanna; Weigand, Bettina
M.; et al. "Whole-body senescent cell clearance alleviates age-related brain inflammation and cognitive impairment in mice".
Aging Cell 20 2 (2021): http://dx.doi.org/10.1111/acel.13296.
10.1111/acel.13296
- Braude, Stan; Holtze, Susanne; Begall, Sabine; Brenmoehl, Julia; Burda, Hynek; Dammann, Philip; Marmol, Delphine; et al. "Surprisingly
long survival of premature conclusions about naked mole-rat biology". Biological Reviews 96 2 (2020): 376-393. http://dx.doi.org/10.1111/brv.12660.
10.1111/brv.12660
- Fielder, Edward; Tweedy, Clare; Wilson, Caroline; Oakley, Fiona; LeBeau, Fiona E. N.; Passos, João F.; Mann, Derek A.; Zglinicki,
Thomas; Jurk, Diana. "Anti-inflammatory treatment rescues memory deficits during aging in
nfkb1
-/-
mice". Aging Cell 19 10 (2020): http://dx.doi.org/10.1111/acel.13188.
10.1111/acel.13188
- Granic, Antoneta; Martin-Ruiz, Carmen; Dodds, Richard M; Robinson, Louise; Spyridopoulos, Ioakim; Kirkwood, Thomas BL; von
Zglinicki, Thomas; Sayer, Avan A. "Immunosenescence profiles are not associated with muscle strength, physical performance
and sarcopenia risk in very old adults: The Newcastle 85+ Study". Mechanisms of Ageing and Development 190 (2020):
111321. http://dx.doi.org/10.1016/j.mad.2020.111321.
10.1016/j.mad.2020.111321
- Martin-Ruiz, Carmen; Williams-Gray, Caroline H.; Yarnall, Alison J.; Boucher, John J.; Lawson, Rachael A.; Wijeyekoon, Ruwani
S.; Barker, Roger A.; et al. "Senescence and Inflammatory Markers for Predicting Clinical Progression in Parkinson’s Disease:
The ICICLE-PD Study". Journal of Parkinson's Disease 10 1 (2020): 193-206. http://dx.doi.org/10.3233/jpd-191724.
10.3233/jpd-191724
- Martin-Ruiz C; Williams-Gray CH; Yarnall AJ; Boucher JJ; Lawson RA; Wijeyekoon RS; Barker RA; et al. "Senescence and Inflammatory
Markers for Predicting Clinical Progression in Parkinson's Disease: The ICICLE-PD Study.". Journal of Parkinson's disease
(2020): http://europepmc.org/abstract/med/31868677.
10.3233/jpd-191724
- Martin-Ruiz C; Hoffmann J; Shmeleva E; Zglinicki TV; Richardson G; Draganova L; Redgrave R; et al. "CMV-independent increase
in CD27-CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians.". NPJ aging and mechanisms of disease
(2020): http://europepmc.org/abstract/med/31993214.
10.1038/s41514-019-0041-y
- Gorgoulis V; Adams PD; Alimonti A; Bennett DC; Bischof O; Bishop C; Campisi J; et al. "Cellular Senescence: Defining a Path
Forward.". Cell (2019): http://europepmc.org/abstract/med/31675495.
10.1016/j.cell.2019.10.005
- Bateson M; Aviv A; Bendix L; Benetos A; Ben-Shlomo Y; Bojesen SE; Cooper C; et al. "Smoking does not accelerate leucocyte
telomere attrition: a meta-analysis of 18 longitudinal cohorts.". Royal Society open science (2019): http://europepmc.org/abstract/med/31312500.
10.1098/rsos.190420
- Ogrodnik M; Zhu Y; Langhi LGP; Tchkonia T; Krüger P; Fielder E; Victorelli S; et al. "Obesity-Induced Cellular Senescence
Drives Anxiety and Impairs Neurogenesis.". Cell metabolism (2019): http://europepmc.org/abstract/med/31067450.
10.1016/j.cmet.2019.01.013
- Fielder E; Weigand M; Agneessens J; Griffin B; Parker C; Miwa S; von Zglinicki T. "Sublethal whole-body irradiation causes
progressive premature frailty in mice.". Mechanisms of ageing and development (2019): http://europepmc.org/abstract/med/30954485.
10.1016/j.mad.2019.03.006
- Palmer AK; Xu M; Zhu Y; Pirtskhalava T; Weivoda MM; Hachfeld CM; Prata LG; et al. "Targeting senescent cells alleviates obesity-induced
metabolic dysfunction.". Aging cell (2019): http://europepmc.org/abstract/med/30907060.
10.1111/acel.12950
- Kucheryavenko O; Nelson G; von Zglinicki T; Korolchuk VI; Carroll B. "The mTORC1-autophagy pathway is a target for senescent
cell elimination.". Biogerontology (2019): http://europepmc.org/abstract/med/30798505.
10.1007/s10522-019-09802-9
- Short S; Fielder E; Miwa S; von Zglinicki T. "Senolytics and senostatics as adjuvant tumour therapy.". EBioMedicine
(2019): http://europepmc.org/abstract/med/30737084.
10.1016/j.ebiom.2019.01.056
- Roger M; Fullard N; Costello L; Bradbury S; Markiewicz E; O'Reilly S; Darling N; et al. "Bioengineering the microanatomy of
human skin.". Journal of anatomy (2019): http://europepmc.org/abstract/med/30740672.
10.1111/joa.12942
- Ogrodnik M; Zhu Y; Langhi LGP; Tchkonia T; Krüger P; Fielder E; Victorelli S; et al. "Obesity-Induced Cellular Senescence
Drives Anxiety and Impairs Neurogenesis.". Cell metabolism (2019): http://europepmc.org/abstract/med/30612898.
10.1016/j.cmet.2018.12.008
- da Silva PFL; Ogrodnik M; Kucheryavenko O; Glibert J; Miwa S; Cameron K; Ishaq A; et al. "The bystander effect contributes
to the accumulation of senescent cells in vivo.". Aging cell (2018): http://europepmc.org/abstract/med/30462359.
10.1111/acel.12848
- Ishaq A; Dufour D; Cameron K; von Zglinicki T; Saretzki G. "Metabolic memory of dietary restriction ameliorates DNA damage
and adipocyte size in mouse visceral adipose tissue.". Experimental gerontology (2018): http://europepmc.org/abstract/med/30312736.
10.1016/j.exger.2018.10.008
- Nelson G; Kucheryavenko O; Wordsworth J; von Zglinicki T. "The senescent bystander effect is caused by ROS-activated NF-¿B
signalling.". Mechanisms of ageing and development (2018): http://europepmc.org/abstract/med/28837845.
10.1016/j.mad.2017.08.005
- Marioni RE; Harris SE; Shah S; McRae AF; von Zglinicki T; Martin-Ruiz C; Wray NR; Visscher PM; Deary IJ. "The epigenetic clock
and telomere length are independently associated with chronological age and mortality.". International Journal of Epidemiology
(2018): http://europepmc.org/abstract/med/29190382.
10.1093/ije/dyx233
- Ishaq A; Schröder J; Edwards N; von Zglinicki T; Saretzki G. "Dietary Restriction Ameliorates Age-Related Increase in DNA
Damage, Senescence and Inflammation in Mouse Adipose Tissuey.". The journal of nutrition, health & aging (2018): http://europepmc.org/abstract/med/29582897.
10.1007/s12603-017-0968-2
- Granic A; Davies K; Martin-Ruiz C; Jagger C; Kirkwood TBL; von Zglinicki T; Aihie Sayer A. "Grip strength and inflammatory
biomarker profiles in very old adults.". Age and ageing (2017): http://europepmc.org/abstract/med/28541423.
10.1093/ageing/afx088
- Korolchuk VI; Miwa S; Carroll B; von Zglinicki T. "Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?". EBioMedicine
(2017): http://europepmc.org/abstract/med/28330601.
10.1016/j.ebiom.2017.03.020
- Carroll B; Nelson G; Rabanal-Ruiz Y; Kucheryavenko O; Dunhill-Turner NA; Chesterman CC; Zahari Q; et al. "Persistent mTORC1
signaling in cell senescence results from defects in amino acid and growth factor sensing.". The Journal of cell biology
(2017): http://europepmc.org/abstract/med/28566325.
10.1083/jcb.201610113
- Ogrodnik M; Miwa S; Tchkonia T; Tiniakos D; Wilson CL; Lahat A; Day CP; et al. "Cellular senescence drives age-dependent hepatic
steatosis.". Nature communications (2017): http://europepmc.org/abstract/med/28608850.
10.1038/ncomms15691
- Hägg S; Zhan Y; Karlsson R; Gerritsen L; Ploner A; van der Lee SJ; Broer L; et al. "Short telomere length is associated with
impaired cognitive performance in European ancestry cohorts.". Translational psychiatry (2017): http://europepmc.org/abstract/med/28418400.
10.1038/tp.2017.73
- Langie SA; Cameron KM; Ficz G; Oxley D; Tomaszewski B; Gorniak JP; Maas LM; et al. "The Ageing Brain: Effects on DNA Repair
and DNA Methylation in Mice.". Genes (2017): http://europepmc.org/abstract/med/28218666.
10.3390/genes8020075
- Stout MB; Steyn FJ; Jurczak MJ; Camporez JG; Zhu Y; Hawse JR; Jurk D; et al. "17a-Estradiol Alleviates Age-related Metabolic
and Inflammatory Dysfunction in Male Mice Without Inducing Feminization.". The Journals of Gerontology Series A: Biological
Sciences and Medical Sciences (2017): http://europepmc.org/abstract/med/26809497.
10.1093/gerona/glv309
- Fielder E; von Zglinicki T; Jurk D. "The DNA Damage Response in Neurons: Die by Apoptosis or Survive in a Senescence-Like
State?". Journal of Alzheimer's disease : JAD (2017): http://europepmc.org/abstract/med/28436392.
10.3233/jad-161221
- von Zglinicki T; Varela Nieto I; Brites D; Karagianni N; Ortolano S; Georgopoulos S; Cardoso AL; et al. "Frailty in mouse
ageing: A conceptual approach.". Mechanisms of ageing and development (2016): http://europepmc.org/abstract/med/27443148.
10.1016/j.mad.2016.07.004
- Skinner R; von Zglinicki T. "Accelerated Aging in Bone Marrow Transplant Survivors.". JAMA oncology (2016): http://europepmc.org/abstract/med/27254135.
10.1001/jamaoncol.2016.0877
- Hewitt G; Carroll B; Sarallah R; Correia-Melo C; Ogrodnik M; Nelson G; Otten EG; et al. "SQSTM1/p62 mediates crosstalk between
autophagy and the UPS in DNA repair.". Autophagy (2016): http://europepmc.org/abstract/med/27391408.
10.1080/15548627.2016.1210368
- Miwa S; Czapiewski R; Wan T; Bell A; Hill KN; von Zglinicki T; Saretzki G. "Decreased mTOR signalling reduces mitochondrial
ROS in brain via accumulation of the telomerase protein TERT within mitochondria.". Aging (2016): http://europepmc.org/abstract/med/27777385.
10.18632/aging.101089
- Spyridopoulos I; Martin-Ruiz C; Hilkens C; Yadegarfar ME; Isaacs J; Jagger C; Kirkwood T; von Zglinicki T. "CMV seropositivity
and T-cell senescence predict increased cardiovascular mortality in octogenarians: results from the Newcastle 85+ study.".
Aging cell (2016): http://europepmc.org/abstract/med/26696322.
10.1111/acel.12430
- Correia-Melo C; Marques FD; Anderson R; Hewitt G; Hewitt R; Cole J; Carroll BM; et al. "Mitochondria are required for pro-ageing
features of the senescent phenotype.". The EMBO journal (2016): http://europepmc.org/abstract/med/26848154.
10.15252/embj.201592862
- Marioni RE; Harris SE; Shah S; McRae AF; von Zglinicki T; Martin-Ruiz C; Wray NR; Visscher PM; Deary IJ. "The epigenetic clock
and telomere length are independently associated with chronological age and mortality.". International journal of epidemiology
(2016): http://europepmc.org/abstract/med/27075770.
10.1093/ije/dyw041
- Vistoli G; Treumann A; Zglinicki Tv; Miwa S. "Data from molecular dynamics simulations in support of the role of human CES1
in the hydrolysis of Amplex Red.". Data in brief (2016): http://europepmc.org/abstract/med/26937463.
10.1016/j.dib.2016.01.031
- Harris SE; Marioni RE; Martin-Ruiz C; Pattie A; Gow AJ; Cox SR; Corley J; et al. "Longitudinal telomere length shortening
and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921.". Mechanisms of ageing and development
(2016): http://europepmc.org/abstract/med/26876762.
10.1016/j.mad.2016.02.004
- Miwa S; Treumann A; Bell A; Vistoli G; Nelson G; Hay S; von Zglinicki T. "Carboxylesterase converts Amplex red to resorufin:
Implications for mitochondrial H2O2 release assays.". Free radical biology & medicine (2016): http://europepmc.org/abstract/med/26577176.
10.1016/j.freeradbiomed.2015.11.011
- Martin-Ruiz CM; Baird D; Roger L; Boukamp P; Krunic D; Cawthon R; Dokter MM; et al. "Reproducibility of telomere length assessment:
an international collaborative study.". International journal of epidemiology (2015): http://europepmc.org/abstract/med/25239152.
10.1093/ije/dyu191
- Arai Y; Martin-Ruiz CM; Takayama M; Abe Y; Takebayashi T; Koyasu S; Suematsu M; Hirose N; von Zglinicki T. "Inflammation,
But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians.".
EBioMedicine (2015): http://europepmc.org/abstract/med/26629551.
10.1016/j.ebiom.2015.07.029
- Martin-Ruiz CM; Baird D; Roger L; Boukamp P; Krunic D; Cawthon R; Dokter MM; et al. "Reproducibility of telomere length assessment:
Authors' Response to Damjan Krstajic and Ljubomir Buturovic.". International journal of epidemiology (2015): http://europepmc.org/abstract/med/26403811.
10.1093/ije/dyv170
- Martin-Ruiz CM; Baird D; Roger L; Boukamp P; Krunic D; Cawthon R; Dokter MM; et al. "Is Southern blotting necessary to measure
telomere length reproducibly? Authors' Response to: Commentary: The reliability of telomere length measurements.". International
journal of epidemiology (2015): http://europepmc.org/abstract/med/26403813.
10.1093/ije/dyv169
- Martin-Ruiz CM; Baird D; Roger L; Boukamp P; Krunic D; Cawthon R; Dokter MM; et al. "Reproducibility of Telomere Length Assessment--An
International Collaborative Study.". International journal of epidemiology (2015): http://europepmc.org/abstract/med/26403809.
10.1093/ije/dyv171
- Holly AC; Grellscheid S; van de Walle P; Dolan D; Pilling LC; Daniels DJ; von Zglinicki T; et al. "Comparison of senescence-associated
miRNAs in primary skin and lung fibroblasts.". Biogerontology (2015): http://europepmc.org/abstract/med/25700689.
10.1007/s10522-015-9560-5
- Mitnitski A; Collerton J; Martin-Ruiz C; Jagger C; von Zglinicki T; Rockwood K; Kirkwood TB. "Age-related frailty and its
association with biological markers of ageing.". BMC medicine (2015): http://europepmc.org/abstract/med/26166298.
10.1186/s12916-015-0400-x
- Granic A; Aspray T; Hill T; Davies K; Collerton J; Martin-Ruiz C; von Zglinicki T; et al. "25-hydroxyvitamin D and increased
all-cause mortality in very old women: the Newcastle 85+ study.". Journal of internal medicine (2015): http://europepmc.org/abstract/med/24889485.
10.1111/joim.12273
- Granic A; Hill TR; Kirkwood TB; Davies K; Collerton J; Martin-Ruiz C; von Zglinicki T; et al. "Serum 25-hydroxyvitamin D and
cognitive decline in the very old: the Newcastle 85+ Study.". European journal of neurology (2015): http://europepmc.org/abstract/med/25117780.
10.1111/ene.12539
- Hoffmann J; Shmeleva EV; Boag SE; Fiser K; Bagnall A; Murali S; Dimmick I; et al. "Myocardial ischemia and reperfusion leads
to transient CD8 immune deficiency and accelerated immunosenescence in CMV-seropositive patients.". Circulation research
(2015): http://europepmc.org/abstract/med/25385851.
10.1161/circresaha.116.304393
- Zglinicki, Thomas. "Metabolism and Aging: From Molecular Physiology to Systems Biology.". Pathobiology of aging & age related
diseases (2015): http://europepmc.org/abstract/med/26725924.
10.3402/pba.v5.30765
- Masi S; D'Aiuto F; Martin-Ruiz C; Kahn T; Wong A; Ghosh AK; Whincup P; et al. "Rate of telomere shortening and cardiovascular
damage: a longitudinal study in the 1946 British Birth Cohort.". European heart journal (2014): http://europepmc.org/abstract/med/24957070.
10.1093/eurheartj/ehu226
- Bennaceur K; Atwill M; Al Zhrany N; Hoffmann J; Keavney B; Breault D; Richardson G; et al. "Atorvastatin induces T cell proliferation
by a telomerase reverse transcriptase (TERT) mediated mechanism.". Atherosclerosis (2014): http://europepmc.org/abstract/med/25127175.
10.1016/j.atherosclerosis.2014.07.020
- Collerton J; Gautrey HE; van Otterdijk SD; Davies K; Martin-Ruiz C; von Zglinicki T; Kirkwood TB; et al. "Acquisition of aberrant
DNA methylation is associated with frailty in the very old: findings from the Newcastle 85+ Study.". Biogerontology
(2014): http://europepmc.org/abstract/med/24770842.
10.1007/s10522-014-9500-9
- Martin-Ruiz C; von Zglinicki T. "Biomarkers of healthy ageing: expectations and validation.". The Proceedings of the Nutrition
Society (2014): http://europepmc.org/abstract/med/24810550.
10.1017/s0029665114000147
- Dalle Pezze P; Nelson G; Otten EG; Korolchuk VI; Kirkwood TB; von Zglinicki T; Shanley DP. "Dynamic modelling of pathways
to cellular senescence reveals strategies for targeted interventions.". PLoS computational biology (2014): http://europepmc.org/abstract/med/25166345.
10.1371/journal.pcbi.1003728
- Baylis D; Ntani G; Edwards MH; Syddall HE; Bartlett DB; Dennison EM; Martin-Ruiz C; et al. "Inflammation, telomere length,
and grip strength: a 10-year longitudinal study.". Calcified tissue international (2014): http://europepmc.org/abstract/med/24858709.
10.1007/s00223-014-9862-7
- Jurk D; Wilson C; Passos JF; Oakley F; Correia-Melo C; Greaves L; Saretzki G; et al. "Chronic inflammation induces telomere
dysfunction and accelerates ageing in mice.". Nature communications (2014): http://europepmc.org/abstract/med/24960204.
10.1038/ncomms5172
- Miwa S; Jow H; Baty K; Johnson A; Czapiewski R; Saretzki G; Treumann A; von Zglinicki T. "Low abundance of the matrix arm
of complex I in mitochondria predicts longevity in mice.". Nature communications (2014): http://europepmc.org/abstract/med/24815183.
10.1038/ncomms4837
- Gardner M; Bann D; Wiley L; Cooper R; Hardy R; Nitsch D; Martin-Ruiz C; et al. "Gender and telomere length: systematic review
and meta-analysis.". Experimental gerontology (2014): http://europepmc.org/abstract/med/24365661.
10.1016/j.exger.2013.12.004
- Cooper R; Stafford M; Hardy R; Aihie Sayer A; Ben-Shlomo Y; Cooper C; Craig L; et al. "Physical capability and subsequent
positive mental wellbeing in older people: findings from five HALCyon cohorts.". Age (Dordrecht, Netherlands) (2014):
http://europepmc.org/abstract/med/23818103.
10.1007/s11357-013-9553-8
- Anderson KN; Catt M; Collerton J; Davies K; von Zglinicki T; Kirkwood TB; Jagger C. "Assessment of sleep and circadian rhythm
disorders in the very old: the Newcastle 85+ Cohort Study.". Age and ageing (2014): http://europepmc.org/abstract/med/24123786.
10.1093/ageing/aft153
- Wiley L; Ashok D; Martin-Ruiz C; Talbot DC; Collerton J; Kingston A; Davies K; et al. "Reactive oxygen species production
and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old.". PloS one (2014):
http://europepmc.org/abstract/med/24614678.
10.1371/journal.pone.0091005
- Alfred T; Ben-Shlomo Y; Cooper R; Hardy R; Cooper C; Deary IJ; Elliott J; et al. "Associations between APOE and low-density
lipoprotein cholesterol genotypes and cognitive and physical capability: the HALCyon programme.". Age (Dordrecht, Netherlands)
(2014): http://europepmc.org/abstract/med/25073452.
10.1007/s11357-014-9673-9
- Spyridopoulos I; von Zglinicki T. "Telomere length predicts cardiovascular disease.". BMJ (Clinical research ed.) (2014):
http://europepmc.org/abstract/med/25005709.
10.1136/bmj.g4373
- Collerton J; Ashok D; Martin-Ruiz C; Pyle A; Hudson G; Yadegarfar M; Davies K; et al. "Frailty and mortality are not influenced
by mitochondrial DNA haplotypes in the very old.". Neurobiology of aging (2013): http://europepmc.org/abstract/med/23639206.
10.1016/j.neurobiolaging.2013.04.001
- Duran AL; Potter P; Wells S; Kirkwood T; von Zglinicki T; McArdle A; Scudamore C; et al. "Shared Ageing Research Models (ShARM):
a new facility to support ageing research.". Biogerontology (2013): http://europepmc.org/abstract/med/24085518.
10.1007/s10522-013-9457-0
- Gorniak JP; Cameron KM; Waldron KJ; von Zglinicki T; Mathers JC; Langie SA. "Tissue differences in BER-related incision activity
and non-specific nuclease activity as measured by the comet assay.". Mutagenesis (2013): http://europepmc.org/abstract/med/24097409.
10.1093/mutage/get047
- Valentijn AJ; Palial K; Al-Lamee H; Tempest N; Drury J; Von Zglinicki T; Saretzki G; et al. "SSEA-1 isolates human endometrial
basal glandular epithelial cells: phenotypic and functional characterization and implications in the pathogenesis of endometriosis.".
Human reproduction (Oxford, England) (2013): http://europepmc.org/abstract/med/23847113.
10.1093/humrep/det285
- Brain JG; Robertson H; Thompson E; Humphreys EH; Gardner A; Booth TA; Jones DE; et al. "Biliary epithelial senescence and
plasticity in acute cellular rejection.". American journal of transplantation : official journal of the American Society
of Transplantation and the American Society of Transplant Surgeons (2013): http://europepmc.org/abstract/med/23750746.
10.1111/ajt.12271
- Alfred T; Ben-Shlomo Y; Cooper R; Hardy R; Deary IJ; Elliott J; Harris SE; et al. "Genetic variants influencing biomarkers
of nutrition are not associated with cognitive capability in middle-aged and older adults.". The Journal of nutrition
(2013): http://europepmc.org/abstract/med/23468552.
10.3945/jn.112.171520
- Gavriilidis C; Miwa S; von Zglinicki T; Taylor RW; Young DA. "Mitochondrial dysfunction in osteoarthritis is associated with
down-regulation of superoxide dismutase 2.". Arthritis and rheumatism (2013): http://europepmc.org/abstract/med/23138846.
10.1002/art.37782
- Alfred T; Ben-Shlomo Y; Cooper R; Hardy R; Cooper C; Deary IJ; Gunnell D; et al. "Genetic markers of bone and joint health
and physical capability in older adults: the HALCyon programme.". Bone (2013): http://europepmc.org/abstract/med/23072920.
10.1016/j.bone.2012.10.004
- Gardner MP; Martin-Ruiz C; Cooper R; Hardy R; Sayer AA; Cooper C; Deary IJ; et al. "Telomere length and physical performance
at older ages: an individual participant meta-analysis.". PloS one (2013): http://europepmc.org/abstract/med/23922731.
10.1371/journal.pone.0069526
- Nelson G; von Zglinicki T. "Monitoring DNA damage during cell senescence.". Methods in molecular biology (Clifton, N.J.)
(2013): http://europepmc.org/abstract/med/23296660.
10.1007/978-1-62703-239-1_13
- Hewitt G; von Zglinicki T; Passos JF. "Cell sorting of young and senescent cells.". Methods in molecular biology (Clifton,
N.J.) (2013): http://europepmc.org/abstract/med/23929096.
10.1007/978-1-62703-556-9_4
- Passos JF; Miwa S; von Zglinicki T. "Measuring reactive oxygen species in senescent cells.". Methods in molecular biology
(Clifton, N.J.) (2013): http://europepmc.org/abstract/med/23296664.
10.1007/978-1-62703-239-1_17
- Hardy R; Cooper R; Aihie Sayer A; Ben-Shlomo Y; Cooper C; Deary IJ; Demakakos P; et al. "Body mass index, muscle strength
and physical performance in older adults from eight cohort studies: the HALCyon programme.". PloS one (2013): http://europepmc.org/abstract/med/23437142.
10.1371/journal.pone.0056483
- Jurk D; Wang C; Miwa S; Maddick M; Korolchuk V; Tsolou A; Gonos ES; et al. "Postmitotic neurons develop a p21-dependent senescence-like
phenotype driven by a DNA damage response.". Aging cell (2012): http://europepmc.org/abstract/med/22882466.
10.1111/j.1474-9726.2012.00870.x
- Verma S; Tachtatzis P; Penrhyn-Lowe S; Scarpini C; Jurk D; Von Zglinicki T; Coleman N; Alexander GJ. "Sustained telomere length
in hepatocytes and cholangiocytes with increasing age in normal liver.". Hepatology (Baltimore, Md.) (2012): http://europepmc.org/abstract/med/22504828.
10.1002/hep.25787
- Masi S; Nightingale CM; Day IN; Guthrie P; Rumley A; Lowe GD; von Zglinicki T; et al. "Inflammation and not cardiovascular
risk factors is associated with short leukocyte telomere length in 13- to 16-year-old adolescents.". Arteriosclerosis,
thrombosis, and vascular biology (2012): http://europepmc.org/abstract/med/22679311.
10.1161/atvbaha.112.250589
- Harris SE; Martin-Ruiz C; von Zglinicki T; Starr JM; Deary IJ. "Telomere length and aging biomarkers in 70-year-olds: the
Lothian Birth Cohort 1936.". Neurobiology of aging (2012): http://europepmc.org/abstract/med/21194798.
10.1016/j.neurobiolaging.2010.11.013
- Collerton J; Martin-Ruiz C; Davies K; Hilkens CM; Isaacs J; Kolenda C; Parker C; et al. "Frailty and the role of inflammation,
immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ Study.". Mechanisms
of ageing and development (2012): http://europepmc.org/abstract/med/22663935.
10.1016/j.mad.2012.05.005
- Lisanti S; von Zglinicki T; Mathers JC. "Standardization and quality controls for the methylated DNA immunoprecipitation technique.".
Epigenetics (2012): http://europepmc.org/abstract/med/22507898.
10.4161/epi.20028
- Tsolou A; Nelson G; Trachana V; Chondrogianni N; Saretzki G; von Zglinicki T; Gonos ES. "The 19S proteasome subunit Rpn7 stabilizes
DNA damage foci upon genotoxic insult.". IUBMB life (2012): http://europepmc.org/abstract/med/22473755.
10.1002/iub.1018
- Nelson G; Wordsworth J; Wang C; Jurk D; Lawless C; Martin-Ruiz C; von Zglinicki T. "A senescent cell bystander effect: senescence-induced
senescence.". Aging cell (2012): http://europepmc.org/abstract/med/22321662.
10.1111/j.1474-9726.2012.00795.x
- Kuh D; Cooper R; Richards M; Gale C; von Zglinicki T; Guralnik J. "A life course approach to healthy ageing: the HALCyon programme.".
Public health (2012): http://europepmc.org/abstract/med/22326597.
10.1016/j.puhe.2012.01.025
- von Zglinicki T. "Will your telomeres tell your future?". BMJ (Clinical research ed.) (2012): http://europepmc.org/abstract/med/22415954.
10.1136/bmj.e1727
- Passos JF; Zglinicki Tv. "Mitochondrial dysfunction and cell senescence--skin deep into mammalian aging.". Aging (2012):
http://europepmc.org/abstract/med/22337807.
10.18632/aging.100432
- Alfred T; Ben-Shlomo Y; Cooper R; Hardy R; Cooper C; Deary IJ; Gaunt TR; et al. "A multi-cohort study of polymorphisms in
the GH/IGF axis and physical capability: the HALCyon programme.". PloS one (2012): http://europepmc.org/abstract/med/22253814.
10.1371/journal.pone.0029883
- Lawless C; Jurk D; Gillespie CS; Shanley D; Saretzki G; von Zglinicki T; Passos JF. "A stochastic step model of replicative
senescence explains ROS production rate in ageing cell populations.". PloS one (2012): http://europepmc.org/abstract/med/22359661.
10.1371/journal.pone.0032117
- Pearce MS; Mann KD; Martin-Ruiz C; Parker L; White M; von Zglinicki T; Adams J. "Childhood growth, IQ and education as predictors
of white blood cell telomere length at age 49-51 years: the Newcastle Thousand Families Study.". PloS one (2012): http://europepmc.org/abstract/med/22792222.
10.1371/journal.pone.0040116
- Cameron KM; Miwa S; Walker C; von Zglinicki T. "Male mice retain a metabolic memory of improved glucose tolerance induced
during adult onset, short-term dietary restriction.". Longevity & healthspan (2012): http://europepmc.org/abstract/med/24764509.
10.1186/2046-2395-1-3
- Hoffmann J; Fiser K; Weaver J; Dimmick I; Loeher M; Pircher H; Martin-Ruiz C; et al. "High-throughput 13-parameter immunophenotyping
identifies shifts in the circulating T-cell compartment following reperfusion in patients with acute myocardial infarction.".
PloS one (2012): http://europepmc.org/abstract/med/23077561.
10.1371/journal.pone.0047155
- Pekovic V; Gibbs-Seymour I; Markiewicz E; Alzoghaibi F; Benham AM; Edwards R; Wenhert M; von Zglinicki T; Hutchison CJ. "Conserved
cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation.". Aging cell
(2011): http://europepmc.org/abstract/med/21951640.
10.1111/j.1474-9726.2011.00750.x
- Martin-Ruiz C; Jagger C; Kingston A; Collerton J; Catt M; Davies K; Dunn M; et al. "Assessment of a large panel of candidate
biomarkers of ageing in the Newcastle 85+ study.". Mechanisms of ageing and development (2011): http://europepmc.org/abstract/med/21864562.
10.1016/j.mad.2011.08.001
- Alfred T; Ben-Shlomo Y; Cooper R; Hardy R; Cooper C; Deary IJ; Gunnell D; et al. "ACTN3 genotype, athletic status, and life
course physical capability: meta-analysis of the published literature and findings from nine studies.". Human mutation
(2011): http://europepmc.org/abstract/med/21542061.
10.1002/humu.21526
- Den Elzen WP; Martin-Ruiz C; von Zglinicki T; Westendorp RG; Kirkwood TB; Gussekloo J. "Telomere length and anaemia in old
age: results from the Newcastle 85-plus Study and the Leiden 85-plus Study.". Age and ageing (2011): http://europepmc.org/abstract/med/21622673.
10.1093/ageing/afr048
- Langie SA; Cameron KM; Waldron KJ; Fletcher KP; von Zglinicki T; Mathers JC. "Measuring DNA repair incision activity of mouse
tissue extracts towards singlet oxygen-induced DNA damage: a comet-based in vitro repair assay.". Mutagenesis (2011):
http://europepmc.org/abstract/med/21355044.
10.1093/mutage/ger005
- Jagger C; Collerton JC; Davies K; Kingston A; Robinson LA; Eccles MP; von Zglinicki T; et al. "Capability and dependency in
the Newcastle 85+ cohort study. Projections of future care needs.". BMC geriatrics (2011): http://europepmc.org/abstract/med/21542901.
10.1186/1471-2318-11-21
- Cameron KM; Golightly A; Miwa S; Speakman J; Boys R; von Zglinicki T. "Gross energy metabolism in mice under late onset, short
term caloric restriction.". Mechanisms of ageing and development (2011): http://europepmc.org/abstract/med/21507329.
10.1016/j.mad.2011.04.004
- Neganova I; Vilella F; Atkinson SP; Lloret M; Passos JF; von Zglinicki T; O'Connor JE; et al. "An important role for CDK2
in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells.". Stem cells (Dayton, Ohio)
(2011): http://europepmc.org/abstract/med/21319273.
10.1002/stem.620
- Birnie K; Cooper R; Martin RM; Kuh D; Sayer AA; Alvarado BE; Bayer A; et al. "Childhood socioeconomic position and objectively
measured physical capability levels in adulthood: a systematic review and meta-analysis.". PloS one (2011): http://europepmc.org/abstract/med/21297868.
10.1371/journal.pone.0015564
- Cooper R; Kuh D; Cooper C; Gale CR; Lawlor DA; Matthews F; Hardy R; FALCon and HALCyon Study Teams. "Objective measures of
physical capability and subsequent health: a systematic review.". Age and ageing (2011): http://europepmc.org/abstract/med/20843964.
10.1093/ageing/afq117
- Miwa S; Lawless C; von Zglinicki T. "Correction of radiolabel pulse-chase data by a mathematical model: application to mitochondrial
turnover studies.". Biochemical Society transactions (2010): http://europepmc.org/abstract/med/20863307.
10.1042/bst0381322
- Lawless C; Wang C; Jurk D; Merz A; Zglinicki Tv; Passos JF. "Quantitative assessment of markers for cell senescence.". Experimental
gerontology (2010): http://europepmc.org/abstract/med/20117203.
10.1016/j.exger.2010.01.018
- Tchkonia T; Morbeck DE; Von Zglinicki T; Van Deursen J; Lustgarten J; Scrable H; Khosla S; Jensen MD; Kirkland JL. "Fat tissue,
aging, and cellular senescence.". Aging cell (2010): http://europepmc.org/abstract/med/20701600.
10.1111/j.1474-9726.2010.00608.x
- Wang C; Maddick M; Miwa S; Jurk D; Czapiewski R; Saretzki G; Langie SA; et al. "Adult-onset, short-term dietary restriction
reduces cell senescence in mice.". Aging (2010): http://europepmc.org/abstract/med/20844316.
10.18632/aging.100196
- Westhoff JH; Schildhorn C; Jacobi C; Hömme M; Hartner A; Braun H; Kryzer C; et al. "Telomere shortening reduces regenerative
capacity after acute kidney injury.". Journal of the American Society of Nephrology : JASN (2010): http://europepmc.org/abstract/med/19959722.
10.1681/asn.2009010072
- Nelson G; von Zglinicki T. "Shifting focus.". Cell cycle (Georgetown, Tex.) (2010): http://europepmc.org/abstract/med/20130449.
- Passos JF; Nelson G; Wang C; Richter T; Simillion C; Proctor CJ; Miwa S; et al. "Feedback between p21 and reactive oxygen
production is necessary for cell senescence.". Molecular systems biology (2010): http://europepmc.org/abstract/med/20160708.
10.1038/msb.2010.5
- Passos JF; Simillion C; Hallinan J; Wipat A; von Zglinicki T. "Cellular senescence: unravelling complexity.". Age (Dordrecht,
Netherlands) (2009): http://europepmc.org/abstract/med/19618294.
10.1007/s11357-009-9108-1
- Collerton J; Davies K; Jagger C; Kingston A; Bond J; Eccles MP; Robinson LA; et al. "Health and disease in 85 year olds: baseline
findings from the Newcastle 85+ cohort study.". BMJ (Clinical research ed.) (2009): http://europepmc.org/abstract/med/20028777.
10.1136/bmj.b4904
- Nelson G; Buhmann M; von Zglinicki T. "DNA damage foci in mitosis are devoid of 53BP1.". Cell cycle (Georgetown, Tex.)
(2009): http://europepmc.org/abstract/med/19806024.
10.4161/cc.8.20.9857
- Domínguez-Garrido E; Martínez-Redondo D; Martín-Ruiz C; Gómez-Durán A; Ruiz-Pesini E; Madero P; Tamparillas M; et al. "Association
of mitochondrial haplogroup J and mtDNA oxidative damage in two different North Spain elderly populations.". Biogerontology
(2009): http://europepmc.org/abstract/med/18931934.
10.1007/s10522-008-9186-y
- Birket MJ; Passos JF; von Zglinicki T; Birch-Machin MA. "The relationship between the aging- and photo-dependent T414G mitochondrial
DNA mutation with cellular senescence and reactive oxygen species production in cultured skin fibroblasts.". The Journal
of investigative dermatology (2009): http://europepmc.org/abstract/med/19052564.
10.1038/jid.2008.373
- Wang C; Jurk D; Maddick M; Nelson G; Martin-Ruiz C; von Zglinicki T. "DNA damage response and cellular senescence in tissues
of aging mice.". Aging cell (2009): http://europepmc.org/abstract/med/19627270.
10.1111/j.1474-9726.2009.00481.x
- Hapangama DK; Turner MA; Drury JA; Quenby S; Hart A; Maddick M; Martin-Ruiz C; von Zglinicki T. "Sustained replication in
endometrium of women with endometriosis occurs without evoking a DNA damage response.". Human reproduction (Oxford, England)
(2009): http://europepmc.org/abstract/med/19088109.
10.1093/humrep/den416
- Ksiazek K; Mikula-Pietrasik J; Olijslagers S; Jörres A; von Zglinicki T; Witowski J. "Vulnerability to oxidative stress and
different patterns of senescence in human peritoneal mesothelial cell strains.". American journal of physiology. Regulatory,
integrative and comparative physiology (2009): http://europepmc.org/abstract/med/19036828.
10.1152/ajpregu.90451.2008
- Adamson AJ; Collerton J; Davies K; Foster E; Jagger C; Stamp E; Mathers JC; Kirkwood T; Newcastle 85+ Study Core Team. "Nutrition
in advanced age: dietary assessment in the Newcastle 85+ study.". European journal of clinical nutrition (2009): http://europepmc.org/abstract/med/19190647.
10.1038/ejcn.2008.60
- Miwa S; Lawless C; von Zglinicki T. "Mitochondrial turnover in liver is fast in vivo and is accelerated by dietary restriction:
application of a simple dynamic model.". Aging cell (2008): http://europepmc.org/abstract/med/18691181.
10.1111/j.1474-9726.2008.00426.x
- Tsolou A; Passos JF; Nelson G; Arai Y; Zglinicki Tv. "ssDNA fragments induce cell senescence by telomere uncapping.". Experimental
gerontology (2008): http://europepmc.org/abstract/med/18778766.
10.1016/j.exger.2008.08.043
- Hapangama DK; Turner MA; Drury JA; Martin-Ruiz C; Von Zglinicki T; Farquharson RG; Quenby S. "Endometrial telomerase shows
specific expression patterns in different types of reproductive failure.". Reproductive biomedicine online (2008):
http://europepmc.org/abstract/med/18765014.
10.1016/s1472-6483(10)60227-1
- Hapangama DK; Turner MA; Drury JA; Quenby S; Saretzki G; Martin-Ruiz C; Von Zglinicki T. "Endometriosis is associated with
aberrant endometrial expression of telomerase and increased telomere length.". Human reproduction (Oxford, England)
(2008): http://europepmc.org/abstract/med/18456668.
10.1093/humrep/den172
- Ahmed S; Passos JF; Birket MJ; Beckmann T; Brings S; Peters H; Birch-Machin MA; von Zglinicki T; Saretzki G. "Telomerase does
not counteract telomere shortening but protects mitochondrial function under oxidative stress.". Journal of cell science
(2008): http://europepmc.org/abstract/med/18334557.
10.1242/jcs.019372
- Aw D; Silva AB; Maddick M; von Zglinicki T; Palmer DB. "Architectural changes in the thymus of aging mice.". Aging cell
(2008): http://europepmc.org/abstract/med/18241323.
10.1111/j.1474-9726.2007.00365.x
- Saretzki G; Walter T; Atkinson S; Passos JF; Bareth B; Keith WN; Stewart R; et al. "Downregulation of multiple stress defense
mechanisms during differentiation of human embryonic stem cells.". Stem cells (Dayton, Ohio) (2008): http://europepmc.org/abstract/med/18055443.
10.1634/stemcells.2007-0628
- Ksiazek K; Passos JF; Olijslagers S; von Zglinicki T. "Mitochondrial dysfunction is a possible cause of accelerated senescence
of mesothelial cells exposed to high glucose.". Biochemical and biophysical research communications (2008): http://europepmc.org/abstract/med/18082137.
10.1016/j.bbrc.2007.12.021
- Richter T; von Zglinicki T. "A continuous correlation between oxidative stress and telomere shortening in fibroblasts.". Experimental
gerontology (2007): http://europepmc.org/abstract/med/17869047.
10.1016/j.exger.2007.08.005
- Ksiazek K; Passos JF; Olijslagers S; Saretzki G; Martin-Ruiz C; von Zglinicki T. "Premature senescence of mesothelial cells
is associated with non-telomeric DNA damage.". Biochemical and biophysical research communications (2007): http://europepmc.org/abstract/med/17720141.
10.1016/j.bbrc.2007.08.047
- Passos JF; von Zglinicki T; Kirkwood TB. "Mitochondria and ageing: winning and losing in the numbers game.". BioEssays
: news and reviews in molecular, cellular and developmental biology (2007): http://europepmc.org/abstract/med/17688237.
10.1002/bies.20634
- Collerton J; Barrass K; Bond J; Eccles M; Jagger C; James O; Martin-Ruiz C; et al. "The Newcastle 85+ study: biological, clinical
and psychosocial factors associated with healthy ageing: study protocol.". BMC geriatrics (2007): http://europepmc.org/abstract/med/17594470.
10.1186/1471-2318-7-14
- Passos JF; Saretzki G; Ahmed S; Nelson G; Richter T; Peters H; Wappler I; et al. "Mitochondrial dysfunction accounts for the
stochastic heterogeneity in telomere-dependent senescence.". PLoS biology (2007): http://europepmc.org/abstract/med/17472436.
10.1371/journal.pbio.0050110
- Richter T; Saretzki G; Nelson G; Melcher M; Olijslagers S; von Zglinicki T. "TRF2 overexpression diminishes repair of telomeric
single-strand breaks and accelerates telomere shortening in human fibroblasts.". Mechanisms of ageing and development
(2007): http://europepmc.org/abstract/med/17395247.
10.1016/j.mad.2007.02.003
- Adams J; Martin-Ruiz C; Pearce MS; White M; Parker L; von Zglinicki T. "No association between socio-economic status and white
blood cell telomere length.". Aging cell (2007): http://europepmc.org/abstract/med/17156082.
10.1111/j.1474-9726.2006.00258.x
- Choudhury AR; Ju Z; Djojosubroto MW; Schienke A; Lechel A; Schaetzlein S; Jiang H; et al. "Cdkn1a deletion improves stem cell
function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation.". Nature genetics
(2007): http://europepmc.org/abstract/med/17143283.
10.1038/ng1937
- Pekovic V; Harborth J; Broers JL; Ramaekers FC; van Engelen B; Lammens M; von Zglinicki T; et al. "Nucleoplasmic LAP2alpha-lamin
A complexes are required to maintain a proliferative state in human fibroblasts.". The Journal of cell biology (2007):
http://europepmc.org/abstract/med/17227891.
10.1083/jcb.200606139
- Collerton J; Martin-Ruiz C; Kenny A; Barrass K; von Zglinicki T; Kirkwood T; Keavney B; Newcastle 85+ Core Study Team. "Telomere
length is associated with left ventricular function in the oldest old: the Newcastle 85+ study.". European heart journal
(2007): http://europepmc.org/abstract/med/17215319.
10.1093/eurheartj/ehl437
- Passos JF; Saretzki G; von Zglinicki T. "DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?".
Nucleic acids research (2007): http://europepmc.org/abstract/med/17986462.
10.1093/nar/gkm893
- Passos JF; von Zglinicki T. "Methods for cell sorting of young and senescent cells.". Methods in molecular biology (Clifton,
N.J.) (2007): http://europepmc.org/abstract/med/17634572.
10.1007/978-1-59745-361-5_4
- Passos JF; Von Zglinicki T. "Oxygen free radicals in cell senescence: are they signal transducers?". Free radical research
(2006): http://europepmc.org/abstract/med/17090417.
10.1080/10715760600917151
- Tchkonia T; Giorgadze N; Pirtskhalava T; Thomou T; DePonte M; Koo A; Forse RA; et al. "Fat depot-specific characteristics
are retained in strains derived from single human preadipocytes.". Diabetes (2006): http://europepmc.org/abstract/med/16936206.
10.2337/db06-0540
- Martin-Ruiz C; Dickinson HO; Keys B; Rowan E; Kenny RA; Von Zglinicki T. "Telomere length predicts poststroke mortality, dementia,
and cognitive decline.". Annals of neurology (2006): http://europepmc.org/abstract/med/16685698.
10.1002/ana.20869
- Jeyapalan JC; Saretzki G; Leake A; Tilby MJ; von Zglinicki T. "Tumour-cell apoptosis after cisplatin treatment is not telomere
dependent.". International journal of cancer (2006): http://europepmc.org/abstract/med/16381006.
10.1002/ijc.21675
- Getliffe KM; Martin Ruiz C; Passos JF; von Zglinicki T; Nwokolo CU. "Extended lifespan and long telomeres in rectal fibroblasts
from late-onset ulcerative colitis patients.". European journal of gastroenterology & hepatology (2006): http://europepmc.org/abstract/med/16394794.
10.1097/00042737-200602000-00005
- Passos JF; von Zglinicki T; Saretzki G. "Mitochondrial dysfunction and cell senescence: cause or consequence?". Rejuvenation
research (2006): http://europepmc.org/abstract/med/16608398.
10.1089/rej.2006.9.64
- Boxall MC; Goodship TH; Brown AL; Ward MC; von Zglinicki T. "Telomere shortening and haemodialysis.". Blood purification
(2006): http://europepmc.org/abstract/med/16373996.
10.1159/000090517
- Martin-Ruiz CM; Gussekloo J; van Heemst D; von Zglinicki T; Westendorp RG. "Telomere length in white blood cells is not associated
with morbidity or mortality in the oldest old: a population-based study.". Aging cell (2005): http://europepmc.org/abstract/med/16300480.
10.1111/j.1474-9726.2005.00171.x
- Warner H; Anderson J; Austad S; Bergamini E; Bredesen D; Butler R; Carnes BA; et al. "Science fact and the SENS agenda. What
can we reasonably expect from ageing research?". EMBO reports (2005): http://europepmc.org/abstract/med/16264422.
10.1038/sj.embor.7400555
- Saretzki G; Armstrong L; Leake A; Lako M; von Zglinicki T. "Stress defense in murine embryonic stem cells is superior to that
of various differentiated murine cells.". Stem cells (Dayton, Ohio) (2004): http://europepmc.org/abstract/med/15536187.
10.1634/stemcells.22-6-962
- d'Adda di Fagagna F; Reaper PM; Clay-Farrace L; Fiegler H; Carr P; Von Zglinicki T; Saretzki G; Carter NP; Jackson SP. "A
DNA damage checkpoint response in telomere-initiated senescence.". Nature (2003): http://europepmc.org/abstract/med/14608368.
10.1038/nature02118
- Von Zglinicki T. "Replicative senescence and the art of counting.". Experimental gerontology (2003): http://europepmc.org/abstract/med/14698805.
10.1016/j.exger.2003.09.015
- Saretzki G; Ludwig A; von Zglinicki T; Runnebaum IB. "Ribozyme-mediated telomerase inhibition induces immediate cell loss
but not telomere shortening in ovarian cancer cells.". Cancer gene therapy (2001): http://europepmc.org/abstract/med/11687906.
10.1038/sj.cgt.7700383
- Sitte N; Merker K; Von Zglinicki T; Davies KJ; Grune T. "Protein oxidation and degradation during cellular senescence of human
BJ fibroblasts: part II--aging of nondividing cells.". FASEB journal : official publication of the Federation of American
Societies for Experimental Biology (2000): http://europepmc.org/abstract/med/11099468.
10.1096/fj.00-0210com
- Sitte N; Merker K; Von Zglinicki T; Grune T; Davies KJ. "Protein oxidation and degradation during cellular senescence of human
BJ fibroblasts: part I--effects of proliferative senescence.". FASEB journal : official publication of the Federation of
American Societies for Experimental Biology (2000): http://europepmc.org/abstract/med/11099467.
10.1096/fj.00-0209com
- von Zglinicki T; Serra V; Lorenz M; Saretzki G; Lenzen-Grossimlighaus R; Gessner R; Risch A; Steinhagen-Thiessen E. "Short
telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor?". Laboratory
investigation; a journal of technical methods and pathology (2000): http://europepmc.org/abstract/med/11092534.
10.1038/labinvest.3780184
- Saretzki G; Feng J; von Zglinicki T; Villeponteau B. "Similar gene expression pattern in senescent and hyperoxic-treated fibroblasts.".
The journals of gerontology. Series A, Biological sciences and medical sciences (1998): http://europepmc.org/abstract/med/9823740.
10.1093/gerona/53a.6.b438
- von Zglinicki T. "Telomeres: influencing the rate of aging.". Annals of the New York Academy of Sciences (1998): http://europepmc.org/abstract/med/9928440.
10.1111/j.1749-6632.1998.tb09912.x
- Müller A; Saretzki G; von Zglinicki T. "Telomerase inhibition by induced expression of antisense RNA.". Advances in experimental
medicine and biology (1998): http://europepmc.org/abstract/med/10026845.
- von Zglinicki T; Saretzki G. "[Molecular mechanisms of senescence in cell culture].". Zeitschrift fur Gerontologie und
Geriatrie (1997): http://europepmc.org/abstract/med/9156811.
- von Zglinicki T. "[Are the ends of chromosomes the beginning of tumor genesis? On the role of telomeres in cancer development]".
Fortschritte der Medizin (1996): http://europepmc.org/abstract/med/9064260.
- von Zglinicki T; Nilsson E; Döcke WD; Brunk UT. "Lipofuscin accumulation and ageing of fibroblasts.". Gerontology (1995):
http://europepmc.org/abstract/med/8821324.
10.1159/000213728
- von Zglinicki T; Roomans GM. "Changes of ion and water content of mouse intestinal cells after pilocarpine and isoproterenol
stimulation.". Scanning microscopy. Supplement (1994): http://europepmc.org/abstract/med/7638491.
- von Zglinicki T; Lindberg M; Roomans GM; Forslind B. "Water and ion distribution profiles in human skin.". Acta dermato-venereologica
(1993): http://europepmc.org/abstract/med/7904397.
- von Zglinicki T; Roomans GM. "Water and ion shifts in mouse intestinal cells following VIP stimulation.". Epithelial cell
biology (1993): http://europepmc.org/abstract/med/8269029.
- von Zglinicki T; Brunk UT. "Intracellular interactions under oxidative stress and aging: a hypothesis.". Zeitschrift fur
Gerontologie (1993): http://europepmc.org/abstract/med/8212789.
- von Zglinicki T; Wiswedel I; Trümper L; Augustin W. "Morphological changes of isolated rat liver mitochondria during Fe2+/ascorbate-induced
peroxidation and the effect of thioctacid.". Mechanisms of ageing and development (1991): http://europepmc.org/abstract/med/2056778.
10.1016/0047-6374(91)90049-6
- von Zglinicki T. "The measurement of water distribution in frozen specimens.". Journal of microscopy (1991): http://europepmc.org/abstract/med/2016733.
- von Zglinicki T. "Reliability of intracellular water and ion distributions as measured by X-ray microanalysis--a review.".
Scanning microscopy. Supplement (1991): http://europepmc.org/abstract/med/1822025.
- Ziervogel H; von Zglinicki T. "[Ions and chromatin structure--morphologic and x-ray microanalytic findings]". Acta histochemica.
Supplementband (1990): http://europepmc.org/abstract/med/2080289.
- Linsel G; Zglinicki T. "Ion distribution in leaf cells of Egeria densa.". Acta histochemica. Supplementband (1990):
http://europepmc.org/abstract/med/2080291.
- von Zglinicki T. "[X-ray microanalysis--possibilities and methods]". Acta histochemica. Supplementband (1990): http://europepmc.org/abstract/med/2080290.
- von Zglinicki T; Ziervogel H; Bimmler M. "Binding of ions to nuclear chromatin.". Scanning microscopy (1989): http://europepmc.org/abstract/med/2633340.
- von Zglinicki T; Roomans GM. "Element concentrations in the intestinal mucosa of the mouse as measured by X-ray microanalysis.".
Scanning microscopy (1989): http://europepmc.org/abstract/med/2814397.
- von Zglinicki T; Zierold K. "Elemental concentrations in air-exposed and vacuum-stored cryosections of rat liver cells.".
Journal of microscopy (1989): http://europepmc.org/abstract/med/2769745.
- Wattig B; Warzok R; von Zglinicki T. "[Morphometric studies of peripheral nerves and spinal ganglion cells in streptozotocin
diabetic rats]". Gegenbaurs morphologisches Jahrbuch (1989): http://europepmc.org/abstract/med/2525499.
- von Zglinicki T. "Monovalent ions are spatially bound within the sarcomere.". General physiology and biophysics (1988):
http://europepmc.org/abstract/med/3234738.
- von Zglinicki T. "Intracellular water distribution and aging as examined by X-ray microanalysis.". Scanning microscopy
(1988): http://europepmc.org/abstract/med/3201206.
- Duncker M; Tönjes R; Rothe C; Scherkenbach C; von Zglinicki T. "[Experimental research on the effect of testosterone on skull
morphogenesis in the rat].". Fortschritte der Kieferorthopadie (1988): http://europepmc.org/abstract/med/3169663.
10.1007/bf02205042
- von Zglinicki T; Uhrík B. "X-ray microanalysis with continuous specimen cooling: is it necessary?". Journal of microscopy
(1988): http://europepmc.org/abstract/med/3193457.
- von Zglinicki T. "A mitochondrial membrane hypothesis of aging.". Journal of theoretical biology (1987): http://europepmc.org/abstract/med/3695544.
10.1016/s0022-5193(87)80123-6
- von Zglinicki T; Bimmler M; Krause W. "Estimation of organelle water fractions from frozen-dried cryosections.". Journal
of microscopy (1987): http://europepmc.org/abstract/med/3599069.
- von Zglinicki T; Bimmler M. "Intracellular water and ionic shifts during growth and ageing of rats.". Mechanisms of ageing
and development (1987): http://europepmc.org/abstract/med/3600050.
10.1016/0047-6374(87)90077-7
- von Zglinicki T; Bimmler M. "The intracellular distribution of ions and water in rat liver and heart muscle.". Journal
of microscopy (1987): http://europepmc.org/abstract/med/3599070.
- Wattig B; Warzok R; von Zglinicki T; Röder H; Radzewitz B. "[Experimental diabetic neuropathy. Morphometric studies of spinal
ganglia cells in short-term streptozotocin-induced diabetes].". Zentralblatt fur allgemeine Pathologie u. pathologische
Anatomie (1987): http://europepmc.org/abstract/med/3037825.
- Von Zglinicki T; Lustyik G. "Loss of water from heart muscle cells during aging of rats as measured by X-ray microanalysis.".
Archives of gerontology and geriatrics (1986): http://europepmc.org/abstract/med/3827400.
10.1016/0167-4943(86)90030-0
- von Zglinicki T; Punkt K. "Localization artefacts in ultracytochemical ion precipitation reactions.". The Histochemical
journal (1986): http://europepmc.org/abstract/med/2940204.
10.1007/bf01676195
- von Zglinicki T; Rimmler M; Purz HJ. "Fast cryofixation technique for X-ray microanalysis.". Journal of microscopy
(1986): http://europepmc.org/abstract/med/3959070.
- von Zglinicki T. "The second messenger system in the stimulation of cellular growth.". Acta histochemica. Supplementband
(1986): http://europepmc.org/abstract/med/3016796.
- Singh KP; David H; von Zglinicki T. "Association between mitochondria and rough endoplasmic reticulum (rer) in rat hepatocytes.".
Pathology, research and practice (1985): http://europepmc.org/abstract/med/4034432.
- von Zglinicki T; Heumann S. "[Improvement of the contrast of electron microscope images by the optical shadow method]". Biofizika
(1985): http://europepmc.org/abstract/med/4074766.
- Singh KP; Krause W; David H; von Zglinicki T. "Effects of chloroquine on hepatocytic organelles in rat.". Experimental
pathology (1985): http://europepmc.org/abstract/med/4043308.
- Duncker M; Döcke F; Moldenhauer U; von Zglinicki T; Wiemann C. "[Experimental studies on the effect of ovarian hormones on
the development of rat mandibles].". Fortschritte der Kieferorthopadie (1984): http://europepmc.org/abstract/med/6596285.
10.1007/bf02167097
- Daimon T; David H; von Zglinicki T; Marx I. "Morphometric study on the absolute volume of differentiating hepatocytes in rats.".
Experimental pathology (1984): http://europepmc.org/abstract/med/6542870.
- von Zglinicki T. "X-ray microanalysis of intracellular elemental distribution.". Folia histochemica et cytobiologica
(1984): http://europepmc.org/abstract/med/6469127.
- von Zglinicki T. "[Quantitative roentgen microanalysis of biological ultrathin sections with aluminum-carbon vapor films as
standards]". Acta histochemica (1983): http://europepmc.org/abstract/med/6410662.
- Solecki R; von Zglinicki T; Müller HM; Clausing P. "Iron overload of spleen, liver and kidney as a consequence of hemolytic
anaemia.". Experimental pathology (1983): http://europepmc.org/abstract/med/6683665.
- Daimon T; David H; von Zglinicki T; Marx I. "Correlated ultrastructural and morphometric studies on the liver during prenatal
development of rats.". Experimental pathology (1982): http://europepmc.org/abstract/med/7117491.
- von Zglinicki T; Uerlings I. "[Electron microscopic preparation of DNA on uncharged carbon films (author's transl)]". Microscopica
acta (1979): http://europepmc.org/abstract/med/226842.
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