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Artur Cavaco-Paulo has an academic background in Chemistry and Enzymology applied to textiles for over 35 years, where the last 20 have also been dedicated to Biotechnology applied to the cosmetics and pharmaceutical fields. As Associate Professor with Habilitation of the School of Engineering of the University of Minho (UMinho), he has supervised 35 PostDoc researchers and +50 doctoral students. He is the leader of the Bioprocess and Bionanotechnology Research Group (BBRG) group at the Centre of Biological Engineering, University of Minho, Portugal. Cavaco-Paulo published ca. 412 documents (h-index 64; Scopus data), covering research in the fields of nano and microformulations for pharmacological and cosmetic applications, fibres and polymers bioprocesses for industry, biocatalysis/enzymology, mechanisms of hair colour and shape modulation, and molecular dynamics simulations of biological interfaces, among other fields of bioengineering and nanotechnology. As Principal Investigator in the Academia, he has participated in 21 funded projects and coordinated 2 European consortia. He is the co-inventor of +40 published patent applications, of which 6 are granted. Artur’s extensive experience in the development of research and consulting activities in the fields of enzymatic processes and nanotechnology encouraged him to found Solfarcos as a spin-off company of UMinho, aiming at developing biotechnology-based solutions for cosmetic and pharmaceutical formulations.
Identificação

Identificação pessoal

Nome completo
Artur Cavaco-Paulo

Nomes de citação

  • Cavaco-Paulo, Artur

Identificadores de autor

Ciência ID
B416-4780-C0BC
ORCID iD
0000-0001-7204-2064

Moradas

  • Universidade do Minho. Dept. Eng. Biologica, Campus Gualtar, 4710-057, Braga, Braga, Portugal (Profissional)

Websites

Domínios de atuação

  • Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Biocatálise
  • Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Bioprodutos Biomateriais
  • Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Químicos Bio-derivados
  • Ciências da Engenharia e Tecnologias - Biotecnologia Industrial - Tecnologias de BioProcessamento
  • Ciências da Engenharia e Tecnologias - Engenharia dos Materiais - Têxteis
  • Ciências da Engenharia e Tecnologias - Nanotecnologia
  • Ciências da Engenharia e Tecnologias - Nanotecnologia - Nanoprocessos

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Português Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Francês Utilizador independente (B1) Utilizador proficiente (C1) Utilizador independente (B1) Utilizador independente (B1)
Formação
Grau Classificação
2003
Concluído
Engenharia Têxtil - Ramo Química Têxtil (Título de Agregado)
Universidade do Minho, Portugal
"Interacções proteícas em processos enzimáticos têxteis" (TESE/DISSERTAÇÃO)
Aprovado
1995
Concluído
Engenharia Têxtil - Ramo Química Têxtil (Doutoramento)
Universidade do Minho, Portugal
"Influência da Agitação Mecânica e da Composição Enzimática no Tratamento do Algodão com Celulases" (TESE/DISSERTAÇÃO)
Aprovado
1992
Concluído
Mestrado em Tecnologia Têxtil (Mestrado)
Universidade do Minho, Portugal
"Amaciamento do Algodão com Celulases" (TESE/DISSERTAÇÃO)
Aprovado
1986
Concluído
Química (Licenciatura)
Universidade de Lisboa, Portugal
"n/a" (TESE/DISSERTAÇÃO)
14 valores
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2011/10 - Atual Professor Associado (Docente Universitário) Universidade do Minho, Portugal
Universidade do Minho Departamento de Engenharia Biológica, Portugal
2008/01 - 2011/09 Professor Associado (Docente Universitário) Universidade do Minho, Portugal
Universidade do Minho - Campus de Azurém, Portugal
1995/11 - 2007/12 Professor Auxiliar (Docente Universitário) Universidade do Minho, Portugal
Universidade do Minho - Campus de Azurém, Portugal
1992/04 - 1995/11 Assistente (Docente Universitário) Universidade do Minho, Portugal
Universidade do Minho - Campus de Azurém, Portugal
1990/10 - 1992/04 Assistente Estagiário (Docente Universitário) Universidade do Minho, Portugal
Universidade do Minho - Campus de Azurém, Portugal
1987/12 - 1990/10 Assistente Estagiário (Docente Universitário) Universidade de Aveiro, Portugal
Universidade de Aveiro Departamento de Química, Portugal
Projetos

Bolsa

Designação Financiadores
2015/10 - 2018/12 Hair Modulation and transdermal delivery by molecular dynamics
Bolsa de Doutoramento
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2014/01 - 2018/04 Monitoring Human Neutrophil Elastase (HNE) in chronic wounds
Bolsa de Doutoramento
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Universidade do Minho Centro de Engenharia Biológica
Concluído
2013/03 - 2017/03 Unravelling and modulating human hair morphology features
Bolsa de Doutoramento
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010/12 - 2015/12 Development of folate-targeted liposomes for rheumatoid arthritis therapy
Bolsa de Doutoramento
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2010/12 - 2015/12 Protein-based nanodevices for therapeutic applications
Bolsa de Doutoramento
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Concluído
2010/10 - 2014/12 Pharmaceutical and industrial protein formulations
Bolsa de Doutoramento
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2007/05 - 2012/06 Development and characterisation of elastase inhibitor peptides for wound dressing applications
bolsa de doutoramento
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2006/11 - 2011/11 Protein disulfide isomerase-assisted functionalization of proteinaceous substrates
Bolsa de Doutoramento
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2008/04 - 2011/04 Sonoproduction of particles for delivery purposes
Bolsa de Doutoramento
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2008/05/01 - 2010/11 PROTEIN MATRICES FOR WOUND DRESSINGS
info:eu-repo/grantAgreement/FCT/SFRH/SFRH2%FBD2%F416032%F2007/PT
Centro de Ciência e Tecnologia Têxtil, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2003/01 - 2008/06 Enzymatic Treatment of Acrylic and cellulose acetate fibres
Bolsa de Doutoramento
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2004/05 - 2008/02 Enzymatic Treatment of Polyamide 6.6 fibres
Bolsa de doutoramento
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2002/04 - 2007/04 Interacção de Ultra-sons Com Sistemas enzimáticos
Bolsa de Doutoramento
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2001/01 - 2005/11 Laccases para aplicações têxteis
Bolsa de Doutoramento
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2002/01 - 2005/09 Tratamento da lã com proteases modificadas
Bolsa Doutoramento
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2002/01 - 2005/04 Degradação de corantes com microorganismos
Bolsa FCT
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2020/06 - 2023/05 HairFolD: Formulations aimed at modulating hair color and shape from the root
01/SAICT/2019
Universidade do Minho Centro de Engenharia Biológica, Portugal
Em curso
2016/01/01 - 2020/06/30 Folate Target Nanodevies To Activated Macrophages For Rheumatoid Arthritis
H2020-NMP-PILOTS-2015, 683356
Investigador responsável
Universidade do Minho Centro de Engenharia Biológica, Portugal
European Commission
Em curso
2012/01 - 2015/01 Novel approaches for prevention of biofilms formed on medical indwelling devices, e.g. catheters,
FP7NMP, 278402
FP7­NMP, 278402
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal

Universidade do Minho Centro de Engenharia Biológica, Portugal
European Commission
Concluído
2009/12 - 2013/11 Folate­based nanobiodevices for integrated diagnosis/therapy targeting chronic inflammatory diseases
FP7NMP, 2288272
FP7­NMP, 228827­2
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
2010/01 - 2013/01 Improved novel eco­friendly bleaching system for cotton using enzyme and ultrasound processes
FP7 SME 243529
FP7 ­ SME 243529
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
2006/12 - 2010/12 Biological process on renewble materials
NMP­NI­4/02456
NMPNI4/02456
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
2006/12 - 2010/12 Multifunctionalized Medical Textiles for wound prevention,
NMP/SME­NI­4/ 016333,
NMP/SMENI4/ 016333,
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
2006/03 - 2009/03 Cellulases for detergent applications
BioSeal
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
2006/01 - 2009/01 Biological detergents
FP6­514437
FP6514437
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
2004/01 - 2007/01 Acceleration of Textile Processes by Ultrasound Technology
NNP2­CT­2003­ 505892
NNP2CT2003 505892
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
2001/09 - 2005/08 Biotechnical Improvement of Synthetic Textile Fibres
Biosyntex, GRD2­2000­30110
Biosyntex, GRD2200030110
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
2002/01 - 2005/01 Treatment of wool with chemically modified proteases
Protex, GRD1­2001­40285
FP6­2004­SME­CO OP­ 032877
FP62004SMECO OP 032877
Protex, GRD1200140285
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
2000/01 - 2002/12 Biotreatment of textile dyes
BIOEFFTEX, GRD1­1999­10435
BIOEFFTEX, GRD1199910435
BPT, GRD1­1999­10671
BPT, GRD1199910671
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
1999/01 - 2002/02 Catalases para pós-branqueamento
EW980009
EW98­0009
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
1987/05 - 2001/02 Reciclagem de celulases em processos têxteis
BE­2157
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
1998/01 - 2001/01 Catalases for Low Water Textile Process
Calwatex, EW98­0009
Calwatex, EW980009
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
1995/12 - 1998/12 Biofinishing of Cotton with Cellulases
BE­2157
Investigador responsável
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído

Outro

Designação Financiadores
2015/05 - 2019/12 Bioproduction of Polyesters
UM- Jiangnan University
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Concluído
2015/05 - 2019/05 Mechanism of polymerisation of catechol with laccase enzymes
UM- Jiangnan University
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Concluído
2015/06 - 2018/11 Ultrasound Assisted Swelling if bacterial cellulose
UM- Sookmyung
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Concluído
2014/10 - 2018/10 Ultrasound enhanced lipase-catalyzed synthesis
UM -ICTMumbai
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
2014/06 - 2017/06 Ultrasound intensification for biodiesel production
UM- ICTMumbai
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Concluído
2011/10 - 2015/05 Phosphorylation of fibrous materials as a “green” method of their functional diversification
NOVO project
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Concluído
2010/10 - 2014/12 Combined laccase-ultrasound processes for industrial applications
COTTONBLEACH
Orientador
Universidade do Minho Centro de Engenharia Biológica, Portugal
Concluído
2008/05 - 2012/06 Sonoproduction of protein microspheres
UM- BIU
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
2007/05 - 2011/05 Biotreatment of Bamboo Fibres
UM - Donghua Univ
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Concluído
2005/05 - 2010/05 genetic Engineered Enzymes for textiles
Interno
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Concluído
2004/03 - 2008/12 Modification of cellulosic fibres using oxiredutases
Interno
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Concluído
2002/04 - 2005/03 Enzymatic treatment of synthetic fibres
UM-TuGRAZ
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
2000/05 - 2003/09 Degradation of dyes with laccases
UM- TUGraz
Orientador
Concluído
2000/06 - 2003/05 Azo-reductases from KF bacterial sp.,
UM- TUGraz
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Concluído
1999/05 - 2002/05 Tratamento enzimático de fibras lenhocelulosicas
UM-DeMontfort Univ
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Concluído
1997/05 - 2000/05 Application of cellulase and laccase in Denim fabrics and for effluent treatment
UM-TUGRAZ
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Concluído
1997/01 - 2000/01 Microbial degradation of textile dyes and effluents
UM-TUGraz
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
Concluído
1996/05 - 1999/05 Biofinishing of cotton fabrics with genetic modified strains of T. reesei cellulases
BE­2157
Orientador
Centro de Ciência e Tecnologia Têxtil, Portugal
European Commission
Concluído
Produções

Publicações

Artigo em conferência
  1. Guimarães, Diana Isabel Pereira; Nogueira, Eugénia Sofia Costa; Cavaco-Paulo, Artur. "Effect of sucrose in freeze-dried liposomes encapsulating drugs". 2018.
  2. Loureiro, Ana Isabel Sá; Cavaco-Paulo, Artur. "Folic acid-tagged protein nanoemulsions with controllable size for cancer therapy". 2018.
  3. Nogueira, Eugénia Sofia Costa; Cavaco-Paulo, Artur. "Folate-targeted nanoparticles for rheumatoid arthritis therapy". 2017.
  4. Matamá, Teresa; Costa, Cristiana c.; Fernandes, Bruno; Guimarães, Diana Isabel Pereira; Cruz, Célia F.; Gomes, Andreia; Cavaco-Paulo, Artur. "Understanding the molecular basis behind hair morphology: development of new strategies to modulate hair from the follicle". 2017.
  5. Loureiro, Ana Isabel Sá; Cavaco-Paulo, Artur. "Size controlled protein nanoemulsions for cancer therapy". 2017.
  6. Martins, Madalena; Cruz, Célia F.; Antunes, Egipto; Ribeiro, Artur; Cavaco-Paulo, Artur. "Straighten curly hair with keratin peptides". 2017.
  7. Noro, Jennifer Martins; Zhao, Xiaoman; Silva, Carla; Cavaco-Paulo, Artur. "Bioproduction of polyesters". 2017.
  8. Nogueira, E.; Cavaco-Paulo, Artur. "Liposomal formulations for rheumatoid arthritis". 2017.
  9. Ribeiro, Artur; Tinoco, Ana Catarina; Cavaco-Paulo, Artur. "Multifunctional proteins for hair protection and coloring". 2017.
  10. Kim, Suyeon; Nakamatsu, Javier; Torres, Fernando; Ribeiro, Artur; Gomes, Andreia; Cavaco-Paulo, Artur. "Laccase-mediated catechin grafting to chitosan for modulating antioxidant, antimicrobial activities and controlled release". 2016.
  11. Su, Jing; Cavaco-Paulo, Artur. "Role of PEG on the formation of polyphenols with laccase enzymes". 2016.
  12. Ferreira, Ana Vanessa Fernandes; Cunha, Joana Marques da; Cavaco-Paulo, Artur. "Monitoring human neutrophil elastase (HNE) in chronic wound". 2016.
  13. Cunha, Joana Marques da; Lima, Rui; Sousa, Helena Isabel Teixeira de; Cavaco-Paulo, Artur. "Chitosan-coated BSA nanoparticles for oral delivery". 2016.
  14. Antunes, José Egipto Ferreira; Azóia, Nuno G.; Cavaco-Paulo, Artur; Antunes, Egipto; Cruz, Célia F.. "Hair keratin molecular dynamics models". 2016.
  15. Antunes, José Egipto Ferreira; Azóia, Nuno G.; Cavaco-Paulo, Artur. "Molecular dynamics simulations together with experimental studies reveal strong membrane activity of a small peptide". 2016.
  16. Nogueira, Eugénia Sofia Costa; Loureiro, Ana; Gomes, A. C.; Cavaco-Paulo, Artur. "Folate-target nanodevices to activated macrophages for rheumatoid arthritis". 2015.
  17. Antunes, José Egipto Ferreira; Azóia, Nuno G.; Cruz, Célia F.; Paulo, Artur Cavaco. "Keratin molecular dynamics models". 2014.
  18. Matamá, Maria Teresa; Guimarães, Diana Isabel Pereira; Costa, Cristiana; Paulo, Artur Cavaco; Gomes, A. C.. "Time-dependent effect of tamoxifen on melanogenesis in normal human melanocytes". 2014.
  19. Volkov, Vadim; Vasconcelos, Andreia; Sárria, M. P.; Gomes, A. C.; Paulo, Artur Cavaco. "Enzymatic phosphorylation of silk fibroins : a platform for the production of biocompatible, cell-static, materials". 2014.
  20. Loureiro, Ana; Gomes, Andreia; Paulo, Artur Cavaco. "Preparation and characterization of protein nanospheres prepared by high pressure homogenization". 2014.
  21. Martins, Madalena A.; Silva, Carla Manuela Pereira Marinho da; Paulo, Artur Cavaco. "Interfacial stabilization of enzymes in microemulsions". 2014.
  22. Gonçalves, Idalina; Botelho, C. M.; Paulo, Artur Cavaco. "Enzymatic polymerization of phenolic compounds". 2014.
  23. Azóia, Nuno G.; Paulo, Artur Cavaco. "Study of transdermal permeation of large molecules bycoarse-grained molecular dynamics simulation". 2014.
  24. Fernandes, Bruno Pacheco; Silva, Raquel; Gomes, A. C.; Paulo, Artur Cavaco. "Development and characterization of PLA nanoparticles as carriers for topical delivery". 2014.
  25. Ribeiro, Artur J.; Borges, C.; Gomes, A. C.; Paulo, Artur Cavaco; Sousa, Filipa Manuela Lopes de; Oliveira, Isabel Andreia Carreira de; Batista, Irineu; Bandarra, Narcisa M.. "Development of therapeutic and cosmetic formulations based on sardine-based products". 2014.
  26. Ribeiro, Artur J.; Lopes, André Moreni; Converti, Attilio; Oliveira, Marcos Antonio de; Motta, Cristina Maria de Souza; Magalhães, Pérola de Oliveira; Farías Avendaño, Jorge Gonzalo; et al. "Production of extracellular L-asparaginase : from bioprospecting to the engineering of an antileukemic biopharmaceutical". 2014.
  27. Gomes, A. C.; Paulo, Artur Cavaco. "Folate-based nanobiodevices for integrated diagnosis/therapy targeting chronic inflammatory diseases". 2014.
  28. Borges, C.; Ribeiro, Artur J.; Carvalho, A. C.; Sousa, F.; Oliveira, I.; Batista, I.; Bandarra, N. M.; Gomes, A. C.; Paulo, Artur Cavaco. "Study of sardine oil antioxidant properties for the development of topical therapeutic formulations". 2014.
    10.1055/s-0034-1395057
  29. Cruz, Célia F.; Botelho, C. M.; Paulo, Artur Cavaco. "Effect of a peptide in cosmetic formulations for hairhumidity-control". 2014.
  30. Kandelbauer, A.; Kessler, R. W.; Sabou, D. -M.; Paulo, Artur Cavaco; Gübitz, Georg M.. "Spectroscopic on-line monitoring and stopped-flow kinetic analysis of dye degradation by laccase/mediator systems". 2014.
  31. Sárria, M. P.; Nogueira, Eugénia; Oliveira, A.; Matamá, Maria Teresa; Guimarães, Diana Isabel Pereira; Borges, C.; Paulo, Artur Cavaco; Gomes, A. C.. "Delivery of cytarabine by pegylated liposomes for efficient, long-term anticancer effects". 2014.
  32. Ferreira, A. V.; Volkov, Vadim; Vasconcelos, Andreia; Abreu, Aana S.; Botelho, C. M.; Paulo, Artur Cavaco. "Silk fibroin nanoparticles for drug delivery purposes : stabilization, incorporation and release design". 2014.
  33. Gonçalves, Idalina; Silva, Carla Manuela Pereira Marinho da; Paulo, Artur Cavaco. "Laccase/ultrasound system for cotton bleaching : an ultrasonic pilot-scale reactor". 2014.
  34. Ribeiro, Artur; Santos, Rui; Nunes, Carlos P.; Sousa, Joao C.; Palha, Joana A.; Sousa, Nuno; Gomes, Andreia C.; Cavaco-Paulo, Artur. "Evaluation of the effect of food iron fortification by ICP-MS on hair samples of elderly people with iron deficiency". 2014.
  35. Trevizano, L. M.; Ventorim, R. Z.; Gachet, C.; Oliveira, E. B.; Paulo, Artur Cavaco; Guimarães, V. M.. "Production and characterization of Orpinomyces mutant xylanases with improved temperature and pH stabilities". 2013.
  36. Gomes, Daniela S.; Matamá, Maria Teresa; Paulo, Artur Cavaco; Jordão, R. C. C.; Takaki, G. M. Campos; Salgueiro, Alexandra A.. "Interactions between glycerol, PEG-200 and (NH4)2 SO4 in the stability of heterologous cutinase". 2013.
  37. Rollett, Alexandra; Reiter, Tamara; Nogueira, Patrícia; Repic, A.; Paulo, Artur Cavaco; Guebitz, G. M.. "Preparation and surface modification of protein nanocapsules for targeted drug delivery". 2013.
  38. Loureiro, Ana; Gomes, Andreia; Cavaco-Paulo, Artur. "Protein based nanoparticles". 2013.
  39. Nogueira, Eugénia Sofia Costa; Preto, Ana; Cavaco-Paulo, Artur. "Liposomal formulations for specific drug delivery". 2013.
  40. Cavaco-Paulo, Artur; Hofmann, Heinrich. "Nanotechnology: definitions and concepts". 2013.
  41. Martins, Madalena; Azoia, Nuno G.; Ribeiro, Artur; Shimanovich, Ulyana; Matama, Teresa; Gomes, Andreia C.; Silva, Carla; Cavaco-Paulo, Artur. "Design of a novel BSA-Hyaluronic acid nanodispersion for transdermal applications". 2013.
  42. Zille, Andrea; Franciscon, E.; Dias, G. F.; Menezes, C. R.; Durrant, L. R.; Paulo, Artur Cavaco. "Biodegradation of textile azo dyes by a facultative Staphylococcus arlettae strain VN-11 using a sequential microaerophilic/aerobic process". 2010.
    Zille, Andrea; Franciscon, Elisangela; Fabio, Dias Guimaro; de Menezes Cristiano, Ragagnin; Durrant, Lucia Regina; Artur, Cavaco-Paulo. Biodegradation of textile azo dyes by a facultative Staphylococcus arlettae strain VN-11 using a sequential microaeroph
  43. Costa, André da; Machado, Raul; Matamá, Maria Teresa; Rodríguez-Cabello, José Carlos; Paulo, Artur Cavaco; Casal, Margarida. "Production and purification of recombinant antimicrobial peptides by exploiting the termoresponsiveness of the elastin-like polymer based on the VPAVG sequence". 2010.
  44. Machado, Raul; Araújo, Rita; Silva, Carla Manuela Pereira Marinho da; Bessa, Paulo C.; Cunha, A. M.; Teixeira, J. A.; Paulo, Artur Cavaco; et al. "Recombinant elastin-like polymers : from the design towards application". 2009.
  45. Zille, Andrea; Franciscon, E.; Durrant, L. R.; Fantinatti-Garboggini, F.; Paulo, Artur Cavaco. "Microaerophilic–aerobic sequential decolourization/biodegradation of textile azo dyes by a facultative klebsiella sp. strain VN-31". 2009.
  46. Martí, M.; Zille, Andrea; Paulo, Artur Cavaco; Coderch, L.; Parra, J. L.. "Enzyme stabilization with liposomes". 2008.
  47. Martí, M.; Zille, Andrea; Paulo, Artur Cavaco; Coderch, L.; Parra, J. L.. "Optimisation of laccase encapsulation in liposomes for the surface treatments of textiles". 2007.
  48. Kim, Su-yeon; Zille, Andrea; Vasconcelos, Andreia; Paulo, Artur Cavaco. "New developments of enzymatic treatments on cellulosic fibers". 2007.
  49. Zille, Andrea; Lopez Diaz, Carmen; Su-Yeon, Kim; Paulo, Artur Cavaco. "SWP4.1 : Functionalisation of cellulosic fibres : characterization of laccase oxidation of lignosulfonates in presence of lignocellulosic substrates". 2007.
  50. Zille, Andrea; Górnacka, B.; Rehorek, A.; Paulo, Artur Cavaco. "Degradation of azo dyes by trametes villosa laccase under long time oxidative conditions". 2006.
  51. Zille, Andrea; Basto, Carlos; Kim, Su-yeon; Paulo, Artur Cavaco. "Laccase-catalyzed polymerization for coating and material modification". 2006.
  52. Zille, Andrea; Moldes, Diego; Irgoliç, Ramona; Paulo, Artur Cavaco. "Enhanced stability of laccase by xylitol". 2006.
  53. Basto, Carlos; Fernandes, Margarida M.; Zille, Andrea; Paulo, Artur Cavaco. "Sono-enzymatic coloration of wool". 2006.
  54. Zille, Andrea; Paulo, Artur Cavaco. "High-energy micro-environments applications in textiles (HEMEAT)". 2006.
  55. Zille, Andrea; Górnacka, B.; Rehorek, A.; Paulo, Artur Cavaco. "Enzymatic degradation of azo dyes under long time oxidative conditions". 2006.
  56. Zille, Andrea; Paulo, Artur Cavaco. "Enzymatic dyeing of wood". 2005.
  57. Zille, Andrea; Munteanu, Florentina-Daniela; Gübitz, Georg M.; Paulo, Artur Cavaco. "Laccase polymerization of amino-phenol compounds". 2005.
  58. Ramalho, Patrícia A.; Ramalho, Maria Teresa; Cardoso, M. Helena; Paulo, Artur Cavaco; Paiva, Sandra; Casal, Margarida. "Reductive biological treatment of textile effluents". 2004.
  59. Ramalho, Patrícia A.; Paiva, Sandra; Paulo, Artur Cavaco; Casal, Margarida; Ramalho, Maria Teresa; Cardoso, M. Helena. "Is Saccharomyces cerevisiae azoreductase the plasma membrane ferric reductase?". 2004.
  60. Górnacka, B.; Zille, Andrea; Paulo, Artur Cavaco; Rehorek, A.. "LC-MS characterization of intermediates and products of acid orange dyes after laccase treatment". 2004.
  61. Zille, Andrea; Munteanu, Florentina-Daniela; Paulo, Artur Cavaco. "Laccases mechanisms". 2004.
  62. Ramalho, Patrícia A.; Paiva, Sandra; Paulo, Artur Cavaco; Casal, Margarida; Ramalho, Maria Teresa; Cardoso, M. Helena. "A contribution for the identification of the azo reductase activity in intact yeast cells". 2004.
  63. Ramalho, Patrícia A.; Paiva, Sandra; Paulo, Artur Cavaco; Casal, Margarida; Ramalho, Maria Teresa; Cardoso, M. Helena. "The azoreductase of yeast cells: a new feature of an old enzyme". 2004.
  64. Ramalho, Patrícia A.; Cardoso, M. Helena; Millward, Roy; Paulo, Artur Cavaco; Ramalho, Maria Teresa. "Study of the effect of redox mediators on the decolorization of azo dyes by ascomycete yeasts". 2003.
  65. Tzanov, Tzanko; Prada, Enrique; Silva, Carla J. S. M.; Zille, Andrea; Paulo, Artur Cavaco. "Enzymatic dyeing of keratinous materials". 2003.
  66. Ramalho, Patrícia A.; Cardoso, M. Helena; Ramalho, Maria Teresa; Paulo, Artur Cavaco. "Azoreductase activity in intact cells of a non-conventional yeast strain". 2002.
  67. Ramalho, Patrícia A.; Cardoso, M. Helena; Paulo, Artur Cavaco; Ramalho, Maria Teresa. "Characterization of the azo reductase activity in a novel ascomycete yeast strain". 2002.
  68. Tzanov, Tzanko; Silva, Carla J. S. M.; Zille, Andrea; Oliveira, Jovita; Paulo, Artur Cavaco. "Enzymatic dyeing of wool". 2002.
  69. Zille, Andrea; Aixalá, Oriol; Basto, C.; Paulo, Artur Cavaco. "Characterization and stability of free and immobilized laccase in the dyestar dyeing effluent". 2002.
  70. Ramalho, Patrícia A.; Cardoso, M. Helena; Paulo, Artur Cavaco; Ramalho, Maria Teresa. "Azo-redutases em células intactas de leveduras não convencionais". 2002.
  71. Cavaco-Paulo, Artur; Almeida, Luis; Bishop, David. "Kinetic and adsorption parameters for Trichoderma reesei cellulases measured during cotton processing". 1997.
  72. Paulo, Artur Cavaco; Almeida, Luís de; Bishop, David. "The treatment of cotton cellulose with trichoderma reesei engineered cellulases". 1996.
Artigo em revista
  1. Yang, Xue; Chen, Xinyi; Wang, Hongbo; Cavaco-Paulo, Artur; Su, Jing. "Co-immobilizing laccase-mediator system by in-situ synthesis of MOF in PVA hydrogels for enhanced laccase stability and dye decolorization efficiency". Journal of Environmental Management 353 (2024): 120114. http://dx.doi.org/10.1016/j.jenvman.2024.120114.
    10.1016/j.jenvman.2024.120114
  2. Roque, Catarina S.; de Castro, Mariana; Castro, Tarsila G.; Silva, Carla; Cavaco-Paulo, Artur; Noro, Jennifer. Autor correspondente: Noro, Jennifer. "Solvent-free synthesis of hydrophobic and amphiphilic esters using a chemically modified lipase from Thermomyces lanuginosus: a comparative study with native and immobilized forms". ChemBioChem (2024): http://dx.doi.org/10.1002/cbic.202300843.
    No prelo • 10.1002/cbic.202300843
  3. Araújo, Gabriela de Moraes Soares; Loureiro, Ana Isabel Sá; Rodrigues, Jamile Lima; Barros, Paula Alice Bezerra; Halicki, Priscila Cristina Bartolomeu; Ramos, Daniela Fernandes; Marinho, Marcelo Augusto Germani; et al. "Toward a Platform for the Treatment of Burns: An Assessment of Nanoemulsions vs. Nanostructured Lipid Carriers Loaded with Curcumin". Biomedicines 11 12 (2023): 3348. http://dx.doi.org/10.3390/biomedicines11123348.
    10.3390/biomedicines11123348
  4. Rocha, Diana; Freitas, David S.; Castro, Tarsila G.; Noro, Jennifer; Cavaco-Paulo, Artur; Silva, Carla. "Hydration is not detrimental for Glycerol:Lactic acid deep eutectic mixtures". Journal of Molecular Liquids 391 (2023): 123249. http://dx.doi.org/10.1016/j.molliq.2023.123249.
    10.1016/j.molliq.2023.123249
  5. Li, Nannan; Freitas, David S.; Santos, Joana; Venâncio, Armando; Noro, Jennifer; Su, Jing; Wang, Hongbo; Silva, Carla; Cavaco-Paulo, Artur. "Laccase-Catalyzed Synthesis of Added-Value Polymers from Cork and Grape Extracts". Journal of Agricultural and Food Chemistry (2023): http://dx.doi.org/10.1021/acs.jafc.3c04798.
    10.1021/acs.jafc.3c04798
  6. Freitas, David S.; Rocha, Diana; Noro, Jennifer; Castro, Tarsila G.; Cavaco-Paulo, Artur; Silva, Carla. "Eutectic Mixtures As Green Solvents for Laccase-Catalyzed Reactions". ACS Sustainable Chemistry & Engineering 11 46 (2023): 16594-16607. http://dx.doi.org/10.1021/acssuschemeng.3c04944.
    10.1021/acssuschemeng.3c04944
  7. Noro, Jennifer; Cabo, Joana; Freitas, David S.; Roque, Catarina S.; de Castro, Mariana; Cavaco-Paulo, Artur; Silva, Carla. "Deep Eutectic Solvents as Suitable Solvents for Lipase-Catalyzed Transesterification Reactions". ChemSusChem (2023): http://dx.doi.org/10.1002/cssc.202300615.
    10.1002/cssc.202300615
  8. Tarsila G. Castro; Manuel Melle-Franco; Cristina E. A. Sousa; Artur Cavaco-Paulo; João C. Marcos. "Non-Canonical Amino Acids as Building Blocks for Peptidomimetics: Structure, Function, and Applications". Biomolecules (2023): https://doi.org/10.3390/biom13060981.
    10.3390/biom13060981
  9. Yu Li; Jing Su; Tarsila G. Castro; Artur Cavaco-Paulo. "Mechanism of Hair Curling via Laccase-Assisted Tyrosine Grafting Using BSA as a Model Protein". Journal of Natural Fibers (2023): https://doi.org/10.1080/15440478.2023.2187506.
    10.1080/15440478.2023.2187506
  10. Shim, Euijin; Silva, Carla; Cavaco-Paulo, Artur; Kim, Hye Rim. "Effects of the modification of bacterial cellulose as a template for the in situ enzyme-catalyzed polymerization of catechol". Textile Research Journal (2023): 004051752311588. http://dx.doi.org/10.1177/00405175231158821.
    10.1177/00405175231158821
  11. Freitas, David S.; Quesado, Vânia; Rocha, Diana; Noro, Jennifer; Martins, Madalena; Cavaco-Paulo, Artur; Silva, Carla. "Lipase-catalysed polymerization of eutectic mixtures". ChemSusChem (2023): http://dx.doi.org/10.1002/cssc.202202374.
    10.1002/cssc.202202374
  12. Bruno Fernandes; Artur Cavaco-Paulo; Teresa Matamá; Fernandes, Bruno Pacheco; Cavaco-Paulo, Artur; Matamá, Maria Teresa Gonçalves Macedo. "A Comprehensive Review of Mammalian Pigmentation: Paving the Way for Innovative Hair Colour-Changing Cosmetics". Biology (2023): https://doi.org/10.3390/biology12020290.
    10.3390/biology12020290
  13. Ferreira, Tiago; Loureiro, Ana; Noro, Jennifer; Cavaco-Paulo, Artur; Castro, Tarsila G.. "Addressing the Structural Organization of Silicone Alternatives in Formulations by Molecular Dynamics Simulations and a Novel Equilibration Protocol". Polymers 15 4 (2023): 796. http://dx.doi.org/10.3390/polym15040796.
    10.3390/polym15040796
  14. Rocha, Diana; Freitas, David S.; Magalhães, Jéssica; Fernandes, Mariana; Silva, Sónia; Noro, Jennifer; Ribeiro, Artur; et al. "NADES-Based Cork Extractives as Green Ingredients for Cosmetics and Textiles". Processes 11 2 (2023): 309. http://dx.doi.org/10.3390/pr11020309.
    10.3390/pr11020309
  15. Yang, X.; Shi, F.; Su, X.; Cavaco-Paulo, Artur; Wang, H.; Su, Jing. "In-situ encapsulation and construction of Lac@HOFs/hydrogel composite for enhancing laccase stability and azo dyes decolorization efficiency". (2023): https://hdl.handle.net/1822/86021.
    10.1016/j.carbpol.2023.121157
  16. Carvalho, José; Silva, Carla; Martins, Madalena; Cavaco-Paulo, Artur. "Insights on the hair keratin structure under different drying conditions". (2023): https://hdl.handle.net/1822/86403.
    10.1080/15440478.2023.2250556
  17. Yang, Xue; Zhao, Jing; Cavaco-Paulo, Artur; Jing Su; Wang, Hongbo. "Encapsulated laccase in bimetallic Cu/Zn ZIFs as stable and reusable biocatalyst for decolorization of dye wastewater". (2023): https://hdl.handle.net/1822/82628.
    10.1016/j.ijbiomac.2023.123410
  18. Castro, Tarsila Gabriel; Ferreira, Tiago; Matamá, Teresa; Florentina-Daniela Munteanu; Cavaco-Paulo, Artur. "Acetylation and phosphorylation processes modulate Taus binding to microtubules: A molecular dynamics study". (2023): https://hdl.handle.net/1822/80674.
    10.1016/j.bbagen.2022.130276
  19. Li, Nannan; Noro, Jennifer; Su, Jing; Wang, Hongbo; Silva, Carla; Cavaco-Paulo, Artur. "Enhancing laccase-assisted polymerization reactions with perfluorinated compounds". Biochemical Engineering Journal 189 (2022): 108736. http://dx.doi.org/10.1016/j.bej.2022.108736.
    10.1016/j.bej.2022.108736
  20. David S. Freitas; Diana Rocha; Tarsila G. Castro; Jennifer Noro; Vânia I. B. Castro; Marta A. Teixeira; Rui L. Reis; Artur Cavaco-Paulo; Carla Silva. "Green Extraction of Cork Bioactive Compounds Using Natural Deep Eutectic Mixtures". ACS Sustainable Chemistry & Engineering (2022): https://doi.org/10.1021/acssuschemeng.2c01422.
    10.1021/acssuschemeng.2c01422
  21. Noro, Jennifer; Cavaco-Paulo, Artur; Silva, Carla. "Chemical modification of lipases: A powerful tool for activity improvement". Biotechnology Journal (2022): 2100523. http://dx.doi.org/10.1002/biot.202100523.
    10.1002/biot.202100523
  22. Tinoco, Ana; Martins, Madalena; Cavaco-Paulo, Artur; Ribeiro, Artur. "Biotechnology of functional proteins and peptides for hair cosmetic formulations". Trends in Biotechnology 40 5 (2022): 591-605. http://dx.doi.org/10.1016/j.tibtech.2021.09.010.
    10.1016/j.tibtech.2021.09.010
  23. Guimarães, Diana; Franck Lager; Gilles Renault; Jamil Guezguez; Michael Burnet; Cunha, Joana; Cavaco-Paulo, Artur; Eugénia Nogueira. "Folate-Targeted Liposomal Formulations Improve Effects of Methotrexate in Murine Collagen-Induced Arthritis". Biomedicines 10 2 (2022): 229-229. http://dx.doi.org/10.3390/biomedicines10020229.
    10.3390/biomedicines10020229
  24. Carvalho, Diana; Ribeiro, Artur; Silva, Carla; Martins, Madalena; Cavaco-Paulo, Artur. "Hair Styling Based on Eutectic Formulations with Peptides". ACS Sustainable Chemistry & Engineering 10 2 (2022): 880-887. http://dx.doi.org/10.1021/acssuschemeng.1c06599.
    10.1021/acssuschemeng.1c06599
  25. Paulo R. Oliveira-Pinto; Nuno Mariz-Ponte; Rose Marie O. F. Sousa; Ana Torres; Fernando Tavares; Artur Ribeiro; Artur Cavaco-Paulo; et al. "Satureja montana Essential Oil, Zein Nanoparticles and Their Combination as a Biocontrol Strategy to Reduce Bacterial Spot Disease on Tomato Plants". Horticulturae 7 12 (2021): 584. https://doi.org/10.3390/horticulturae7120584.
    10.3390/horticulturae7120584
  26. Li, Nannan; Su, Jing; Wang, Hongbo; Cavaco-Paulo, Artur. "Production of antimicrobial powders of guaiacol oligomers by a laccase-catalyzed synthesis reaction". Process Biochemistry 111 (2021): 213-220. http://dx.doi.org/10.1016/j.procbio.2021.07.018.
    10.1016/j.procbio.2021.07.018
  27. Noro, Jennifer; Cavaco-Paulo, Artur; Silva, Carla. "Chemically Modified Lipase from Thermomyces lanuginosus with Enhanced Esterification and Transesterification Activities". ChemCatChem 13 21 (2021): 4524-4531. http://dx.doi.org/10.1002/cctc.202101050.
    10.1002/cctc.202101050
  28. Ana Tinoco; André F. Costa; Salomé Luís; Madalena Martins; Artur Cavaco-Paulo; Artur Ribeiro. "Proteins as Hair Styling Agents". Applied Sciences 11 9 (2021): 4245-4245. https://doi.org/10.3390/app11094245.
    10.3390/app11094245
  29. Ribeiro, Artur; Martins, Madalena; Tinoco, Ana; Cavaco-Paulo, Artur. "Hair resistance to mechanical wear". Wear 470-471 (2021): 203612. http://dx.doi.org/10.1016/j.wear.2021.203612.
    10.1016/j.wear.2021.203612
  30. Guimarães, Diana; Cavaco-Paulo, Artur; Nogueira, Eugénia. "Design of liposomes as drug delivery system for therapeutic applications". International Journal of Pharmaceutics (2021): 120571. http://dx.doi.org/10.1016/j.ijpharm.2021.120571.
    10.1016/j.ijpharm.2021.120571
  31. Cristiana Costa; Bruno Fernandes; Diana Guimarães; Eugénia Nogueira; Madalena Martins; Teresa Matamá; Artur Cavaco-Paulo. "Comparing the delivery to the hair bulb of two fluorescent molecules of distinct hydrophilicities by different nanoparticles and a serum formulation". International Journal of Pharmaceutics (2021): https://doi.org/10.1016/j.ijpharm.2021.120653.
    10.1016/j.ijpharm.2021.120653
  32. Yuwei Liu; Su Jing; Diana Carvalho; Jiajia Fu; Madalena Martins; Artur Cavaco-Paulo. "Cellulose Dissolved in Ionic Liquids for Modification of the Shape of Keratin Fibers". ACS Sustainable Chemistry & Engineering 9 11 (2021): 4102-4110. https://doi.org/10.1021/acssuschemeng.0c08945.
    10.1021/acssuschemeng.0c08945
  33. Gonçalves, Filipa; Ribeiro, Artur; Silva, Carla; Cavaco-Paulo, Artur. "Biotechnological applications of mammalian odorant-binding proteins". Critical Reviews in Biotechnology (2021): 1-22. http://dx.doi.org/10.1080/07388551.2020.1853672.
    10.1080/07388551.2020.1853672
  34. Castro, Tarsila G.; Silva, Carla; Matamá, Teresa; Cavaco-Paulo, Artur. "The Structural Properties of Odorants Modulate Their Association to Human Odorant Binding Protein". Biomolecules 11 2 (2021): 145. http://dx.doi.org/10.3390/biom11020145.
    10.3390/biom11020145
  35. Rodrigues, Rui M.; Pereira, Ricardo N.; Vicente, António A.; Cavaco-Paulo, Artur; Ribeiro, Artur. "Ohmic heating as a new tool for protein scaffold engineering". Materials Science and Engineering: C 120 (2021): 111784. http://dx.doi.org/10.1016/j.msec.2020.111784.
    10.1016/j.msec.2020.111784
  36. Tinoco, Ana; Gonçalves, Filipa; Costa, André F.; Freitas, David S.; Cavaco-Paulo, Artur; Ribeiro, Artur. "Keratin:Zein particles as vehicles for fragrance release on hair". Industrial Crops and Products 159 (2021): 113067. http://dx.doi.org/10.1016/j.indcrop.2020.113067.
    10.1016/j.indcrop.2020.113067
  37. Li, Yu; Noro, Jennifer; Martins, Madalena; Jing, Su; Silva, Carla; Cavaco-Paulo, Artur. "Changing the shape of wool yarns via laccase-mediated grafting of tyrosine". Journal of Biotechnology 339 (2021): 73-80. http://www.scopus.com/inward/record.url?eid=2-s2.0-85112705621&partnerID=MN8TOARS.
    10.1016/j.jbiotec.2021.08.001
  38. Ghaheh, Fatemeh S.; Noro, Jennifer; Vatankhah, Elham; Tehrani, Sayed P. R.; Cavaco-Paulo, Artur; Silva, Carla. "The comfort properties of cosmeto-textiles functionalized with protein-based nanoemulsions encapsulating Vitamin-E". Journal of Natural Fibers (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85106314421&partnerID=MN8TOARS.
    10.1080/15440478.2021.1921657
  39. Li, Yu; Noro, Jennifer; Li, Jie; Silva, Carla; Su, Jing; Cavaco-Paulo, Artur. "Grafting of Poly(tyrosine) by Laccase Improves the Tensile Strength and Anti-shrinkage of Wool". Journal of Natural Fibers (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85119403934&partnerID=MN8TOARS.
    10.1080/15440478.2021.2002785
  40. Su, Jing; Cavaco-Paulo, Artur. "Effect of ultrasound on protein functionality". (2021): http://hdl.handle.net/1822/73479.
    10.1016/j.ultsonch.2021.105653
  41. Scacchetti, Fabio A. P.; Fernandes, Filipa; Ribeiro, Artur; Cavaco-Paulo, Artur; Carneiro, Joaquim O.; Soares, Graca M. B.. "Antimicrobial Properties of Composites of Chitosan-Silver Doped Zeolites". Journal of Nanoscience and Nanotechnology 20 10 (2020): 6295-6304. http://dx.doi.org/10.1166/jnn.2020.18574.
    10.1166/jnn.2020.18574
  42. Gonçalves, José; Torres, Natália; Silva, Sónia; Gonçalves, Filipa; Noro, Jennifer; Cavaco-Paulo, Artur; Ribeiro, Artur; Silva, Carla. "Zein impart hydrophobic and antimicrobial properties to cotton textiles". Reactive and Functional Polymers 154 (2020): 104664. http://dx.doi.org/10.1016/j.reactfunctpolym.2020.104664.
    10.1016/j.reactfunctpolym.2020.104664
  43. Egipto Antunes; Artur Cavaco-Paulo. "Stratum Corneum Lipid Matrix with Unusual Packing: A Molecular Dynamics Study". Colloids and Surfaces B: Biointerfaces (2020): https://doi.org/10.1016/j.colsurfb.2020.110928.
    10.1016/j.colsurfb.2020.110928
  44. Sofia Moura; Jennifer Noro; Patrícia Cerqueira; Carla Silva; Artur Cavaco-Paulo; Ana Loureiro. "Poloxamer 407 based-nanoparticles for controlled release of methotrexate". International Journal of Pharmaceutics 575 (2020): 118924-118924. https://doi.org/10.1016/j.ijpharm.2019.118924.
    10.1016/j.ijpharm.2019.118924
  45. Tinoco, Ana; Rodrigues, Rui M.; Machado, Raul; Pereira, Ricardo N.; Cavaco-Paulo, Artur; Ribeiro, Artur. "Ohmic heating as an innovative approach for the production of keratin films". International Journal of Biological Macromolecules (2020): http://dx.doi.org/10.1016/j.ijbiomac.2020.02.122.
    10.1016/j.ijbiomac.2020.02.122
  46. Noro, Jennifer; Castro, Tarsila G.; Cavaco-Paulo, Artur; Silva, Carla. "a-Chymotrypsin catalyses the synthesis of methotrexate oligomers". Process Biochemistry 98 (2020): 193-201. http://www.scopus.com/inward/record.url?eid=2-s2.0-85089736155&partnerID=MN8TOARS.
    10.1016/j.procbio.2020.08.004
  47. Shim, Euijin; Noro, Jennifer; Cavaco-Paulo, Artur; Kim, Hye Rim; Silva, Carla. "Carboxymethyl Cellulose (CMC) as a Template for Laccase-Assisted Oxidation of Aniline". Frontiers in Bioengineering and Biotechnology 8 (2020): http://www.scopus.com/inward/record.url?eid=2-s2.0-85085482437&partnerID=MN8TOARS.
    10.3389/fbioe.2020.00438
  48. Guimarães, Diana; Noro, Jennifer; Loureiro, Ana; Lager, Franck; Renault, Gilles; Cavaco-Paulo, Artur; Nogueira, Eugénia. "Increased encapsulation efficiency of methotrexate in liposomes for rheumatoid arthritis therapy". Biomedicines 8 12 (2020): 1-15. http://www.scopus.com/inward/record.url?eid=2-s2.0-85098654668&partnerID=MN8TOARS.
    10.3390/biomedicines8120630
  49. Jennifer Noro; Tarsila G. Castro; Artur Cavaco-Paulo; Carla Silva; Noro, Jennifer; Castro, Tarsila; Cavaco-Paulo, Artur; Silva, Carla. "Substrate hydrophobicity and enzyme modifiers play a major role in the activity of lipase from Thermomyces lanuginosus". Catalysis Science & Technology (2020): https://doi.org/10.1039/D0CY00912A.
    Aceite para publicação • 10.1039/D0CY00912A
  50. Costa, Tiago; Ribeiro, Artur; Machado, Raul; Ribeiro, Clarisse; Lanceros-Mendez, Senentxu; Cavaco-Paulo, Artur; Almeida, Andreia; et al. "Polymeric Electrospun Fibrous Dressings for Topical Co-delivery of Acyclovir and Omega-3 Fatty Acids". Frontiers in Bioengineering and Biotechnology 7 (2019): http://dx.doi.org/10.3389/fbioe.2019.00390.
    10.3389/fbioe.2019.00390
  51. Ana Tinoco; Egipto Antunes; Madalena Martins; Filipa Gonçalves; Andreia C. Gomes; Carla Silva; Artur Cavaco-Paulo; et al. "Fusion proteins with chromogenic and keratin binding modules". Scientific Reports (2019): https://doi.org/10.1038/s41598-019-50283-0.
    10.1038/s41598-019-50283-0
  52. Filipa Gonçalves; Artur Ribeiro; Carla Silva; Artur Cavaco-Paulo. "Release of Fragrances from Cotton Functionalized with Carbohydrate-Binding Module Proteins". ACS Applied Materials & Interfaces (2019): https://doi.org/10.1021/acsami.9b08191.
    10.1021/acsami.9b08191
  53. Mariela Elgegren; Suyeon Kim; Diego Cordova; Carla Silva; Jennifer Noro; Artur Cavaco-Paulo; Javier Nakamatsu; et al. "Ultrasound-Assisted Encapsulation of Sacha Inchi (Plukenetia volubilis Linneo.) Oil in Alginate-Chitosan Nanoparticles". Polymers 11 8 (2019): 1245-1245. https://doi.org/10.3390/polym11081245.
    10.3390/polym11081245
  54. Patrícia Cerqueira; Jennifer Noro; Sofia Moura; Diana Guimarães; Carla Silva; Artur Cavaco-Paulo; Ana Loureiro; et al. "PTS micelles for the delivery of hydrophobic methotrexate". International Journal of Pharmaceutics 566 (2019): 282-290. https://doi.org/10.1016/j.ijpharm.2019.05.049.
    10.1016/j.ijpharm.2019.05.049
  55. Ana V. Ferreira; Egipto Antunes; Artur Ribeiro; Teresa Matamá; Nuno G. Azoia; Joana Cunha; Artur Cavaco-Paulo; et al. "Design of a chromogenic substrate for elastase based on split GFP system—Proof of concept for colour switch sensors". Biotechnology Reports 22 (2019): e00324-e00324. https://doi.org/10.1016/j.btre.2019.e00324.
    10.1016/j.btre.2019.e00324
  56. Jennifer Noro; Tarsila G. Castro; Filipa Gonçalves; Artur Ribeiro; Artur Cavaco-Paulo; Carla Silva; Noro, Jennifer; et al. "Catalytic Activation of Esterases by PEGylation for Polyester Synthesis". ChemCatChem (2019): https://doi.org/10.1002/cctc.201900451.
    10.1002/cctc.201900451
  57. Tarsila Castro; Florentina-Daniela Munteanu; Artur Cavaco-Paulo; Castro, Tarsila Gabriel; Munteanu, Florentina-Daniela; Cavaco-Paulo, Artur. "Electrostatics of Tau Protein by Molecular Dynamics". Biomolecules (2019): https://doi.org/10.3390/biom9030116.
    10.3390/biom9030116
  58. Jing Su; Jennifer Noro; Sónia Silva; Jiajia Fu; Qiang Wang; Artur Ribeiro; Carla Silva; et al. "Antimicrobial coating of textiles by laccase in situ polymerization of catechol and p-phenylenediamine". Reactive and Functional Polymers 136 (2019): 25-33. https://doi.org/10.1016/j.reactfunctpolym.2018.11.015.
    10.1016/j.reactfunctpolym.2018.11.015
  59. Jing Su; Jennifer Noro; Jiajia Fu; Qiang Wang; Carla Silva; Artur Cavaco-Paulo; Su, Jing; et al. "Coloured and low conductive fabrics by in situ laccase-catalysed polymerization". Process Biochemistry 77 (2019): 77-84. https://doi.org/10.1016/j.procbio.2018.11.007.
    10.1016/j.procbio.2018.11.007
  60. Ana Tinoco; Marisa P. Sárria; Ana Loureiro; Pier Parpot; Begoña Espiña; Andreia C. Gomes; Artur Cavaco-Paulo; et al. "BSA/ASN/Pol407 nanoparticles for acute lymphoblastic leukemia treatment". Biochemical Engineering Journal 141 (2019): 80-88. https://doi.org/10.1016/j.bej.2018.10.006.
    10.1016/j.bej.2018.10.006
  61. Xiaoman Zhao; Jennifer Noro; Jiajia Fu; Carla Silva; Artur Cavaco-Paulo; Zhao, Xiaoman; Noro, Jennifer Martins; et al. "Strategies for the synthesis of fluorinated polyesters". RSC Advances (2019): https://doi.org/10.1039/C8RA10341K.
    10.1039/C8RA10341K
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  296. Costa, S.A.; Tzanov, T.; Filipa Carneiro, A.; Paar, A.; Gübitz, G.M.; Cavaco-Paulo, A.; Costa, Silgia; et al. "Studies of stabilization of native catalase using additives". Enzyme and Microbial Technology 30 3 (2002): 387-391. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037070499&partnerID=MN8TOARS.
    10.1016/S0141-0229(01)00505-1
  297. Tzanov, T.; Costa, S.A.; Gübitz, G.M.; Cavaco-Paulo, A.; Tzanov, Tzanko; Costa, Silgia; Gübitz, Georg M.; Paulo, Artur Cavaco. "Hydrogen peroxide generation with immobilized glucose oxidase for textile bleaching". Journal of Biotechnology 93 1 (2002): 87-94. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037203576&partnerID=MN8TOARS.
    10.1016/S0168-1656(01)00386-8
  298. Tzanov, T.; Stamenova, M.; Betcheva, R.; Cavaco-Paulo, A.; Tzanov, Tzanko; Stamenova, Maria; Betcheva, Rossica; Paulo, Artur Cavaco. "Lipases to improve the performance of formaldehyde-free durable press finished cotton fabrics". Macromolecular Materials and Engineering 287 7 (2002): 462-465. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037189699&partnerID=MN8TOARS.
    10.1002/1439-2054(20020701)287:7<462::AID-MAME462>3.0.CO;2-9
  299. Tzanov, T.; Stamenova, M.; Cavaco-Paulo, A.; Tzanov, Tzanko; Stamenova, Maria; Paulo, Artur Cavaco. "Phosphorylation of cotton cellulose with baker's yeast hexokinase". Macromolecular Rapid Communications 23 16 (2002): 962-964. http://www.scopus.com/inward/record.url?eid=2-s2.0-0037175998&partnerID=MN8TOARS.
    10.1002/1521-3927(200211)23:16<962::AID-MARC962>3.0.CO;2-B
  300. Fernández-Sánchez, C.; Tzanov, T.; Gübitz, G.M.; Cavaco-Paulo, A.; Fernández-Sánchez, César; Tzanov, Tzanko; Gübitz, Georg M.; Paulo, Artur Cavaco. "Voltammetric monitoring of laccase-catalysed mediated reactions". Bioelectrochemistry 58 2 (2002): 149-156. http://www.scopus.com/inward/record.url?eid=2-s2.0-0036888637&partnerID=MN8TOARS.
    10.1016/S1567-5394(02)00119-6
  301. Azevedo, H.; Pereira Ramos, L.; Cavaco-Paulo, A.; Azevedo, Helena S.; Ramos, Luiz Pereira; Paulo, Artur Cavaco. "Desorption of cellulases from cotton powder". Biotechnology Letters 23 17 (2001): 1445-1448. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034807260&partnerID=MN8TOARS.
    10.1023/A:1011619425613
  302. Shin, H.; Guebitz, G.; Cavaco-Paulo, A.; Shin, Hoonsik; Gübitz, Georg M.; Paulo, Artur Cavaco. ""In situ" enzymatically prepared polymers for wool coloration". Macromolecular Materials and Engineering 286 11 (2001): 691-694. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035977121&partnerID=MN8TOARS.
    10.1002/1439-2054(20011101)286:11<691::AID-MAME691>3.0.CO;2-A
  303. Gudelj, M.; Fruhwirth, G.O.; Paar, A.; Lottspeich, F.; Robra, K.-H.; Cavaco-Paulo, A.; Gübitz, G.M.. "A catalase-peroxidase from a newly isolated thermoalkaliphilic Bacillus sp. with potential for the treatment of textile bleaching effluents". Extremophiles 5 6 (2001): 423-429. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035751685&partnerID=MN8TOARS.
    10.1007/s007920100218
  304. Tzanov, T.; Calafell, M.; Guebitz, G.M.; Cavaco-Paulo, A.; Tzanov, Tzanko; Calafell, Margarita; Gübitz, Georg M.; Paulo, Artur Cavaco. "Bio-preparation of cotton fabrics". Enzyme and Microbial Technology 29 6-7 (2001): 357-362. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035807426&partnerID=MN8TOARS.
    10.1016/S0141-0229(01)00388-X
  305. Gübitz, G.M.; Cavaco-Paulo, A.; Gübitz, Georg M.; Paulo, Artur Cavaco. "Biotechnology in the textile industry - Perspectives for the new millennium". Journal of Biotechnology 89 2-3 (2001): 89-90. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035940078&partnerID=MN8TOARS.
    10.1016/S0168-1656(01)00317-0
  306. Campos, R.; Kandelbauer, A.; Robra, K.H; Cavaco-Paulo, A.; Gübitz, G.M. "Indigo degradation with purified laccases from Trametes hirsuta and Sclerotium rolfsii". Journal of Biotechnology 89 2-3 (2001): 131-139. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035940061&partnerID=MN8TOARS.
    10.1016/S0168-1656(01)00303-0
  307. Balakshin, M.Y.; Evtuguin, D.V.; Pascoal Neto, C.; Cavaco-Paulo, A.; Balakshin, M. Yu.; Evtuguin, D. V.; Neto, C. Pascoal; Paulo, Artur Cavaco. "Polyoxometalates as mediators in the laccase catalyzed delignification". Journal of Molecular Catalysis - B Enzymatic 16 3-4 (2001): 131-140. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035904855&partnerID=MN8TOARS.
    10.1016/S1381-1177(01)00054-6
  308. Costa, S.A.; Tzanov, T.; Paar, A.; Gudelj, M.; Gübitz, G.M.; Cavaco-Paulo, A.; Costa, Silgia; et al. "Immobilization of catalases from Bacillus SF on alumina for the treatment of textile bleaching effluents". Enzyme and Microbial Technology 28 9-10 (2001): 815-819. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035822019&partnerID=MN8TOARS.
    10.1016/S0141-0229(01)00335-0
  309. Paar, A.; Costa, S.; Tzanov, T.; Gudelj, M.; Robra, K.-H.; Cavaco-Paulo, A.; Gübitz, G.M.. "Thermo-alkali-stable catalases from newly isolated Bacillus sp. for the treatment and recycling of textile bleaching effluents". Journal of Biotechnology 89 2-3 (2001): 147-153. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035940062&partnerID=MN8TOARS.
    10.1016/S0168-1656(01)00305-4
  310. Tauber, M.M.; Cavaco-Paulo, A.; Robra, K.-H.; Gübitz, G.M.; Tauber, Michael; Paulo, Artur Cavaco; Robra, K. B.; Gübitz, Georg M.. "Nitrile hydratase and amidase from Rhodococcus rhodochrous hydrolyze acrylic fibers and granular polyacrylonitriles". Applied and Environmental Microbiology 66 4 (2000): 1634-1638. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034127002&partnerID=MN8TOARS.
    10.1128/AEM.66.4.1634-1638.2000
  311. Abadulla, E.; Tzanov, T.; Costa, S.; Robra, K.-H.; Cavaco-Paulo, A.; Gubitz, G.M.; Abadulla, Ellias; et al. "Decolorization and detoxification of textile dyes with a laccase from Trametes hirsuta". Applied and Environmental Microbiology 66 8 (2000): 3357-3362. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033903003&partnerID=MN8TOARS.
    10.1128/AEM.66.8.3357-3362.2000
  312. Andreaus, J.; Ramos, L.P.; Cavaco-Paulo, A.; Juergen, Andreaus; Ramos, Luiz Pereira; Paulo, Artur Cavaco. "Dry action of Trichoderma reesei cellulases on cotton fabrics". Journal of the Society of Dyers and Colourists 116 4 (2000): 121-125. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034006025&partnerID=MN8TOARS.
  313. Azevedo, H.; Bishop, D.; Cavaco-Paulo, A.; Azevedo, Helena S.; Bishop, David; Paulo, Artur Cavaco. "Effects of agitation level on the adsorption, desorption, and activities on cotton fabrics of full length and core domains of EGV (Humicola insolens) and CenA (Cellulomonas fimi)". Enzyme and Microbial Technology 27 3-5 (2000): 325-329. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034255675&partnerID=MN8TOARS.
    10.1016/S0141-0229(00)00205-2
  314. Andreaus, J.; Azevedo, H.; Cavaco-Paulo, A.; Andreaus, Juergen; Azevedo, Helena S.; Paulo, Artur Cavaco. "Effects of temperature on the cellulose binding ability of cellulase enzymes". Journal of Molecular Catalysis - B Enzymatic 7 1-4 (1999): 233-239. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032838814&partnerID=MN8TOARS.
    10.1016/S1381-1177(99)00032-6
  315. Cavaco-Paulo, A.; Morgado, J.; Andreaus, J.; Kilburn, D.; Paulo, Artur Cavaco; Morgado, José; Andreaus, Juergen; Kilburn, Douglas. "Interactions of cotton with CBD peptides". Enzyme and Microbial Technology 25 8-9 (1999): 639-643. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033230314&partnerID=MN8TOARS.
    10.1016/S0141-0229(99)00101-5
  316. Heikinheimo, L.; Cavaco-Paulo, A.; Nousiainen, P.; Siika-aho, M.; Buchert, J.; Heikinheimo, Lea; Paulo, Artur Cavaco; et al. "Treatment of cotton fabrics with purified Trichoderma reesei cellulases". Journal of the Society of Dyers and Colourists 114 7-8 (1998): 216-220. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031714056&partnerID=MN8TOARS.
  317. Cavaco-Paulo, A.; Paulo, Artur Cavaco. "Mechanism of cellulase action in textile processes". Carbohydrate Polymers 37 3 (1998): 273-277. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032204689&partnerID=MN8TOARS.
    10.1016/S0144-8617(98)00070-8
  318. Cavaco-Paulo, A.; Jose Rios, M.; Paulo, Artur Cavaco; Rios, M. José. "Mechanical properties of cellulase-treated fabrics analyzed". American Dyestuff Reporter 86 9 (1997): 20-28. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031229608&partnerID=MN8TOARS.
  319. Cavaco-Paulo, A.; Cortez, J.; Almeida, L.. "The effect of cellulase treatment in textile washing processes". Journal of the Society of Dyers and Colourists 113 7-8 (1997): 218-222. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030783132&partnerID=MN8TOARS.
  320. Hes, L.; Pinheiro, F.M.; Goncalves, M.M.C.; Cavaco-Paulo, A.; Hes, Lubos; Pinheiro, Fátima Maria Ferreira; Miranda, M. C. Gonçalves; Paulo, Artur Cavaco. "The effect of selected mechanical properties acquired by the KES-F instruments on the level of puckering of cotton fabrics after washing". International Journal of Clothing Science and Technology 9 2-3 (1997): 188-192. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031438727&partnerID=MN8TOARS.
  321. Cavaco-Paulo, A.; Almeida, L.; Almeida, Luís de; Paulo, Artur Cavaco. "Kinetic parameters measured during cellulase processing of cotton". Journal of the Textile Institute 87 1 PART I (1996): 227-233. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029732131&partnerID=MN8TOARS.
    10.1080/00405009608659070
  322. Cavaco-Paulo, A.; Almeida, L.; Bishop, D.. "Cellulase activities and finishing effects". Textile Chemist and Colorist 28 6 (1996): 28-29. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030153207&partnerID=MN8TOARS.
  323. Cavaco-Paulo, A.; Almeida, L.; Paulo, Artur Cavaco; Almeida, Luís de. "Cellulase hydrolysis of cotton cellulose: The effects of mechanical action, enzyme concentration and dyed substrates". Biocatalysis and Biotransformation 10 1-4 (1994): 353-360. http://www.scopus.com/inward/record.url?eid=2-s2.0-84907037025&partnerID=MN8TOARS.
    10.3109/10242429409065244
  324. Almeida, L.; Cavaco-Paulo, A.; Almeida, Luís de; Paulo, Artur Cavaco. "Softening of cotton by enzymatic hydrolysis". Melliand Textilberichte 74 5 (1993): 404-407 + E184. http://www.scopus.com/inward/record.url?eid=2-s2.0-0027389879&partnerID=MN8TOARS.
  325. Cavaco Paulo, A.; Almeida, L.. "The enzymatic hydrolysis of cotton as a new technique for softening". Nova Textil 21 (1991): 59-64. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026084245&partnerID=MN8TOARS.
Capítulo de livro
  1. Nierstrasz, Vincent A.; Cavaco-Paulo, Artur; Qiang Wang. "Preface [to Advances in textile biotechnology]". Woodhead Publishing Limited, 2019.
    10.1016/B978-0-08-102632-8.05001-5
  2. Martins, Madalena; Silva, Carla; Cavaco-Paulo, Artur. "Enzyme stabilization for biotechnological applications". In Advances in Textile Biotechnology, 107-131. Elsevier, 2019.
    10.1016/b978-0-08-102632-8.00006-2
  3. Zhao, Xiaoman; Cavaco-Paulo, Artur; Silva, Carla. "Biosynthesis of polyesters and their application on cellulosic fibers". In Advances in Textile Biotechnology, 49-75. Elsevier, 2019.
    10.1016/b978-0-08-102632-8.00004-9
  4. Silva, C.; Cavaco-Paulo, A.M.; Fu, J.J.. "Enzymatic biofinishes for synthetic textiles". 153-191. 2015.
Documento de trabalho
  1. Ramalho, Patrícia A.; Paiva, Sandra; Paulo, Artur Cavaco; Casal, Margarida; Cardoso, M. Helena; Ramalho, Maria Teresa. 2005. "Role of the component Fre1p of the plasma membrane ferric reductase on the azo reductase activity of intact Saccharomyces cerevisiae cells". http://hdl.handle.net/1822/2326.
Livro
  1. Martins, Madalena; Silva, Carla; Cavaco-Paulo, Artur. 6 - Enzyme stabilization for biotechnological applications. Woodhead Publishing Limited. 2019.
    10.1016/B978-0-08-102632-8.00006-2
  2. Matamá, Maria Teresa Gonçalves Macedo; Cavaco-Paulo, Artur. Cellulose biomodification with cutinase fusion proteins. Research Signpost. 2014.
  3. Silva, Carla Manuela Pereira Marinho da; Cavaco-Paulo, Artur; Fu, J. J.. Enzymatic biofinishes for synthetic textiles. Woodhead Publishing Limited. 2014.
    10.1533/9780857098450.1.153
  4. Paulo, Artur Cavaco. IPFB 2014 - 8th International Conference on Polymer and Fiber Biotechnology: Book of Abstracts. Universidade do Minho. Departamento de Engenharia Biológica (DEB). 2014.
  5. Cavaco-Paulo, Artur; Hofmann-Amtenbrink, Margarethe; NANOFOL – NanoDiaRa Conference 7th Framework Programme, Lisboa, 2013. Nanoparticles for early diagnostics of inflammatory diseases: new approaches in the field of soft and hard nanoparticles: NANOFOL NanoDiaRa Conference 7th Framework Programme. 2013.
  6. Shimanovich, U.; Kim, S.; Ribeiro, A.; Cavaco-Paulo, A.; Gedanken, A.. Using casein protein for microspheres' synthesis, encapsulation drug and textile coatings. 2012.
  7. Silva, R.; Ferreira, H.; Vasconcelos, A.; Gomes, A.C.; Cavaco-Paulo, A.. Sonochemical proteinaceous microspheres for wound healing. 2011.
    10.1007/978-94-007-2555-3-15
  8. Araújo, Rita; Fernandes, Margarida M.; Paulo, Artur Cavaco; Gomes, Andreia; Araújo, R.; Fernandes, M.; Cavaco-Paulo, A.; Gomes, A.. Biology of human hair: Know your hair to control it. Springer. 2011.
    10.1007/10_2010_88
  9. Nierstrasz, V.A.; Cavaco-Paulo, A.. Advances in textile biotechnology. 2010.
  10. Araújo, R.; Casal, M.; Cavaco-paulo, A.. Design and engineering of novel enzymes for textile applications. 2010.
    10.1533/9780857090232.1.3
  11. Silva, C.; Cavaco-Paulo, A.; Nierstrasz, V.A.. Enzymatic hydrolysis and modification of core polymer fibres for textile and other applications. 2010.
    10.1533/9780857090232.2.77
  12. Matamá, T.; Cavaco-Paulo, A.. Enzymatic modification of polyacrylonitrile and cellulose acetate fibres for textile and other applications. 2010.
    10.1533/9780857090232.2.98
  13. Nierstrasz, V.A.; Cavaco-Paulo, A.. Preface. 2010.
    10.1016/B978-1-84569-625-2.50018-8
  14. Munteanu, F.-D.; Dinca, N.; Cavaco-Paulo, A.; Munteanu, Florentina-Daniela; Dinca, Nicolae; Paulo, Artur Cavaco. MALDI-TOF mass spectrometry in textile industry. Springer. 2008.
    10.1007/978-1-4020-8811-7_13
  15. Kandelbauer, A.; Cavaco-Paulo, A.; Gübitz, G.M.. Biotechnological treatment of textile dye effluent. 2007.
    10.1533/9781845693091.212
  16. Kim, S.-Y.; Zilie, A.; Vasconcelos, A.; Cavaco-Paulo, A.. New developments of enzymatic treatments on cellulosic fibers. 2007.
  17. Tzanov, T.; Cavaco-Paulo, A.. Surface modification of cellulose fibers with hydrolases and kinases. 2006.
    10.1007/1-4020-3794-5_10
  18. Cavaco-Paulo, A.. Processing Textile Fibers with Enzymes: An Overview. 1998.
  19. Cavaco-Paulo, A.; Rios, M.J.. Analysis of the mechanical properties of cellulase treated fabrics. 1996.
  20. Cavaco-Paulo, A.; Almeida, L.. Cellulase activities and finishing effects. 1995.
Poster em conferência
  1. Mariana Castro; Cavaco-Paulo, Artur; Noro, Jennifer. Autor correspondente: Mariana Castro. "Silicone alternatives for cosmetic applications". Trabalho apresentado em 5th Symposium in Medicinal Chemistry, 2022.
  2. Catarina Roque; Castro, Tarsila G.; Cavaco-Paulo, Artur; Noro, Jennifer. Autor correspondente: Catarina Roque. "Biosynthesis of new emulsifying compounds for cosmetic applications". Trabalho apresentado em 5th Symposium in Medicinal Chemistry, 2022.
  3. Ferreira, Tiago; Castro, Tarsila G.; Monteanu, Florentina-Daniela; Cavaco-Paulo, Artur. "Acetylation's role in tau structure, electrostatics and interactions: molecular dynamics studies". Trabalho apresentado em BOD 2020 - IX Bioinformatics Open Days, 2020.
Pré-impressão
  1. Yu Li; Jennifer Noro; Jie Li; Carla Silva; Jing Su; Artur Cavaco-Paulo. "Laccase-catalyzed poly(tyrosine) grafting improves the performance of wool". 2024. https://doi.org/10.22541/au.170665833.32468138/v1.
    10.22541/au.170665833.32468138/v1
Tese / Dissertação
  1. Antunes, José Egipto Ferreira. "Hair modulation and transdermal delivery: optimization through molecular dynamics simulations". Doutoramento, 2019. http://hdl.handle.net/1822/60660.
  2. Ferreira, Ana Vanessa Fernandes. "Monitoring Human Neutrophil Elastase (HNE) in chronic wounds". Doutoramento, 2018. http://hdl.handle.net/1822/59040.
  3. Cruz, Célia Freitas da. "Unravelling and modulating human hair morphology features". Doutoramento, 2017. http://hdl.handle.net/1822/48622.
  4. Sousa, Helena Isabel Teixeira de. "Optimization of mucoadhesive and mucopenetrant coatings for nanoformulations for oral delivery". Mestrado, 2016. http://hdl.handle.net/1822/44736.
  5. Volkov, Vadim. "Phosphorylation of fibrous materials as a “green” method of their functional diversification". Doutoramento, 2015. http://hdl.handle.net/1822/38555.
  6. Nogueira, Eugénia Sofia Costa. "Development of folate-targeted liposomes for rheumatoid arthritis therapy". Doutoramento, 2015. http://hdl.handle.net/1822/40446.
  7. Lima, Rui Augusto Ribeiro. "Desenvolvimento de revestimentos de nanopartículas para administração oral". Mestrado, 2015. http://hdl.handle.net/1822/37299.
  8. Borges, C.. "Study of sardine oil antioxidant anti-inflammatory properties for the development of topical therapeutic and cosmetic formulations". Mestrado, 2015. http://hdl.handle.net/1822/35703.
  9. Costa, Cristiana Filipa Chaves. "Localizing the expression of pertinent genes for hair shape by in situ hybridization". Mestrado, 2015. http://hdl.handle.net/1822/34774.
  10. Tinoco, Ana Catarina Malheiro. "Chemical functionalization in bionanoparticles". Mestrado, 2015. http://hdl.handle.net/1822/41123.
  11. Guimarães, Diana Isabel Pereira. "Searching an in vitro cell model to study the chemical modulation of melanogenesis by Tamoxifen". Mestrado, 2015. http://hdl.handle.net/1822/34787.
  12. Loureiro, Ana Isabel Sá. "Protein-based nanodevices for therapeutic applications". Doutoramento, 2015. http://hdl.handle.net/1822/40463.
  13. Sá, Maria Madalena Alves Martins de. "Pharmaceutical and industrial protein formulations". Doutoramento, 2014. http://hdl.handle.net/1822/35847.
  14. Gonçalves, Idalina. "Combined laccase-ultrasound processes for industrial applications". Doutoramento, 2014. http://hdl.handle.net/1822/35673.
  15. Ferreira, Ana Vanessa Fernandes. "Incorporation of elastase inhibitor in silk fibroin nanoparticles for transdermal delivery". Mestrado, 2013. http://hdl.handle.net/1822/28648.
  16. Sousa, Filipa Manuela Lopes de. "Nano-system based on sardine oil formulations for pharmaceutical application". Mestrado, 2013. http://hdl.handle.net/1822/27916.
  17. Fernandes, Bruno Pacheco. "Preparation of particles for cosmetic applications in human hair". Mestrado, 2012. http://hdl.handle.net/1822/23114.
  18. Oliveira, Isabel Andreia Carreira de. "Development of bioactive sardine oil based formulations". Mestrado, 2012. http://hdl.handle.net/1822/23426.
  19. Barros, Sandra Cerqueira. "Development and characterization of elastase inhibitor-peptides for wound dressing applications". Doutoramento, 2012. http://hdl.handle.net/1822/22900.
  20. Antunes, José Egipto Ferreira. "Estudo da interação entre péptidos e membranas celulares por dinâmica molecular e ensaios experimentais : o caso dos péptidos com atividade membranar". Mestrado, 2012. http://hdl.handle.net/1822/22731.
  21. Silva, Raquel. "Sonoproduction of particles for delivery purposes". Doutoramento, 2011. http://hdl.handle.net/1822/14251.
  22. Vasconcelos, Andreia. "Protein matrices for wound dressings". Doutoramento, 2011. http://hdl.handle.net/1822/12495.
  23. Fernandes, Margarida M.. "Protein disulfide isomerase-assisted functionalization of proteinaceous substrates". Doutoramento, 2011. http://hdl.handle.net/1822/19687.
  24. Costa, André da. "Cloning and expression of antimicrobial peptides and their evaluation for biotechnological applications". Mestrado, 2010. http://hdl.handle.net/1822/13360.
  25. Caparrós Vásquez, Cristina Maria. "Cellulases for detergent applications". Doutoramento, 2009. http://hdl.handle.net/1822/9513.
  26. Kim, Suyeon. "Modification of cellulosic fibres using oxidoreductases". Doutoramento, 2009. http://hdl.handle.net/1822/9500.
  27. Silva, Carla Manuela Pereira Marinho da. "Enzymatic treatment of polyamide 6.6 fibres". Doutoramento, 2008. http://hdl.handle.net/1822/8242.
  28. Matamá, Maria Teresa. "Enzymatic treatment of acrylic and cellulose acetate fibres". Doutoramento, 2008. http://hdl.handle.net/1822/8996.
  29. Araújo, Rita. "Molecular biotechnology approaches towards the optimization of enzymes for advanced textile applications". Doutoramento, 2008. http://hdl.handle.net/1822/9120.
  30. Basto, Carlos. "Interacção de ultra-sons com sistemas enzimáticos para aplicações têxteis". Doutoramento, 2007. http://hdl.handle.net/1822/7029.
  31. Silva, Raquel. "Tratamento de fibras têxteis com ultra-sons e enzimas". Mestrado, 2006. http://hdl.handle.net/1822/6395.
  32. Zille, Andrea. "Laccase reactions for textile applications". Doutoramento, 2005. http://hdl.handle.net/1822/4899.
  33. Ramalho, Patrícia A.. "Degradation of dyes with microorganisms : studies with ascomycete yeasts". Doutoramento, 2005. http://hdl.handle.net/1822/3335.
  34. Silva, Carla J. S. M.. "Enzymatic treatment of wool with modified proteases". Doutoramento, 2005. http://hdl.handle.net/1822/3378.
  35. O'Neill, Jaime Alexandre Antunes. "Efeito de solventes orgânicos nas propriedades de fibras sintéticas". Mestrado, 2003. http://hdl.handle.net/1822/388.
  36. Silva, Carla Manuela Pereira Marinho da. "Tratamento alcalino e enzimático de fibras sintéticas". Mestrado, 2002. http://hdl.handle.net/1822/4886.
  37. Paulo, Artur Cavaco. "Influência da agitação mecânica e da composição enzimática no tratamento do algodão com celulases". Doutoramento, 1995. http://hdl.handle.net/1822/4898.

Propriedade Intelectual

Patente
  1. Cavaco-Paulo, Artur; Gonçalves, Filipa Daniela Gomes; Ribeiro, Artur; Silva, Carla Manuela Pereira Marinho da. 2022. "Fragrance release mechanism, method and uses thereof".
  2. Cavaco-Paulo, Artur; Silva, C.; Freitas, David Silva; Noro, Jennifer Martins. 2022. "Eutectic compositions, methods and uses thereof".
  3. Cavaco-Paulo, Artur; Matamá, Teresa; Costa, Cristiana C.; Fernandes, Bruno Pacheco. 2021. "Composition for hair follicle modulation, methods and uses thereof".
  4. Cavaco-Paulo, Artur; Doutora Maria Teresa Matamá; Costa, Cristiana; Fernandes, Bruno. 2020. "Composition for Hair Follicle Modulation, Methods and Uses thereof".
  5. Guimarães, Diana Isabel Pereira; Nogueira, Eugénia; Cavaco-Paulo, Artur. 2020. "Method for production of liposomes".
  6. Paulo, Artur Cavaco; Preto, Ana; Nogueira, Eugénia; Gomes, A. C.. 2013. "Liposomes and corresponding production method".
  7. Paulo, Artur Cavaco; Gomes, A. C.; Silva, Raquel; Loureiro, Ana; Preto, Ana. 2013. "Formulations for micelle formation comprising a protein and methods preparation thereof".

Outros

Outra produção
  1. alpha-Chymotrypsin catalysed oligopeptide synthesis for hair modelling. Conventional chemical treatments imply the use of harsh chemicals which can cause serious adverse effects on consumers health, hair fibre and environment. In this work was reported for the first time the modelling shape of Asian hair by oligopeptide coating synthesized by a protease. ?-Chymotrypsin from Bovine pancreas catalysed the oligomerization of the tri-peptides, KCL (Lysine-Cysteine-Leucine. 2019. Martins, Madalena; Silva, Carla Manuela Pereira Marinho; Cavaco-Paulo, Artur. http://hdl.handle.net/1822/61058.
    10.1016/j.jclepro.2019.117743
  2. Quantification of drugs encapsulated in liposomes by 1H NMR. Liposomes are one of the most important and extensively studied drug delivery system due to their ability to encapsulate different kinds of drugs. Exploiting the advantages of 1H Nuclear Magnetic Resonance (NMR) spectrometry, we established a rapid and easy method for quantification of drugs encapsulated in liposomes. An internal standard, pyridine, was used for quantitative determination of drug. 2019. Guimarães, Diana Isabel Pereira; Noro, Jennifer Martins; Loureiro, Ana Isabel Sá; Cavaco-Paulo, Artur; Nogueira, Eugénia Sofia Costa. http://hdl.handle.net/1822/60440.
    10.1016/j.colsurfb.2019.03.039
  3. Ultrasound-assisted biosynthesis of novel methotrexate-conjugates. New methotrexate-acylglycerols and methotrexate-cyclodextrins (, and -CD) conjugates were obtained via esterification or transesterification reactions. All reactions were catalysed by esterases namely immobilized Lipase from Candida antarctica B and Lipase from Thermomyces lanuginosus. The use of ultrasound to assist the reactions revealed to be a key factor to obtain high conversion yields on bot. 2018. Noro, Jennifer Martins; Reis, R. L.; Cavaco-Paulo, Artur; Silva, Carla. http://hdl.handle.net/1822/55082.
    10.1016/j.ultsonch.2018.05.017
  4. The absence of albumin improves in vitro cellular uptake and disruption of Poloxamer 407-based nanoparticles inside cancer cells. Novel nanoparticles based on Poloxamer 407 and vegetable oil were produced by high pressure homogenization. Functionalization of those nanoparticles was made by incorporation of folic acid (FA)-Poloxamer 407 conjugate. These nanoparticles showed suitable characteristics for intravenous therapeutic applications similarly to PEGylated albumin-based nanoparticles, previously described by our research. 2018. Loureiro, Ana Isabel Sá; Jennifer Noro; Abreu, Ana S.; Nogueira, E.; Soares da Costa, Diana; Silva, Carla; Cavaco-Paulo, Artur. http://hdl.handle.net/1822/51753.
    10.1021/acs.molpharmaceut.7b00893
  5. Ultrasound-assisted lipase catalyzed hydrolysis of aspirin methyl ester. The ultrasound-assisted hydrolysis of aspirin methyl ester (AME) was investigated using immobilized Candida antarctica lipase B (CALB) (1%) in the presence of solvents like triolein, chloroform (CHCl3) and dichloromethane (DCM). The effect of ultrasound and the role of water on the conversion rates have also been investigated. Proton nuclear magnetic resonance spectroscopic (1H NMR) was chosen to. 2018. Chiplunkar, Pranali P.; Zhao, Xiaoman; Tomke, Prerana D.; Noro, Jennifer; Xu, B.; Wang, Qiang; Silva, Carla; Pratap, Amit P.; Cavaco-Paulo, Artur. http://hdl.handle.net/1822/47807.
    10.1016/j.ultsonch.2017.08.004
  6. Permeation of skin with (C60) fullerene dispersions. Dispersions in transcutol/isopropyl myristate make C60 fullerene molecules suitable for transdermal delivery. We found that C60 can successfully permeate the skin using pig skin in Franz diffusion cells. Molecular dynamics simulations and transmission electron microscopy confirmed these observations. Basic cosmetic formulations with transcutol/ isopropyl myristate without harsh organic solvents sh. 2017. Sá, M.; Azóia, Nuno G.; Melle-Franco, Manuel; Ribeiro, Artur; Cavaco-Paulo, Artur. http://hdl.handle.net/1822/46390.
    10.1002/elsc.201600244
  7. Changing the shape of hair with keratin peptides. Chemical straightening of curly human hair fibres involves the use of strong reducing agents at alkaline pH. Human hair is made of keratin, and the fixation of fibre shape involves the reduction and reformation of new disulphide bonds between keratin molecules. Here, we propose an alternative and green methodology using keratin peptide sequences (10-13 residues) derived from the human genome. In a. 2017. Cruz, Célia F.; Sá, M.; Antunes, Egipto; Osorio, H.; Ribeiro, Artur; Cavaco-Paulo, Artur; C. F. Cruz; et al. http://hdl.handle.net/1822/47751.
    10.1039/c7ra10461h
  8. Neutral PEGylated liposomal formulation for efficient folate-mediated delivery of MCL1 siRNA to activated macrophages. Cationic liposomes are efficient vectors for systemic delivery of therapeutic small interfering RNA (siRNA), taking advantage of RNA interference (RNAi), a naturally occurring gene-silencing mechanism in mammalian cells. However, toxicity at high concentrations, short circulating half-lives and lack of specificity restrict their successful application in a wider scale. The purpose of this study wa. 2017. Nogueira, E.; Freitas, Jaime; Loureiro, Ana Isabel Sá; Nogueira, Patrícia; Gomes, Andreia C.; Preto, Ana; Carmo, Alexandre M.; et al. http://hdl.handle.net/1822/47698.
    10.1016/j.colsurfb.2017.04.023
  9. Folate-targeted nanoparticles for rheumatoid arthritis therapy. Rheumatoid arthritis (RA) is the most common inflammatory rheumatic disease, affecting almost 1% of the world population. Although the cause of RA remains unknown, the complex interaction between immune mediators (cytokines and effector cells) is responsible for the joint damage that begins at the synovial membrane. Activated macrophages are critical in the pathogenesis of RA and have been shown t. 2016. Nogueira, Eugénia Sofia Costa; Gomes, Andreia C.; Preto, Ana; Cavaco-Paulo, Artur. http://hdl.handle.net/1822/41371.
    10.1016/j.nano.2015.12.365
  10. Update on therapeutic approaches for rheumatoid arthritis. Rheumatoid arthritis is a common chronic inflammatory and destructive arthropathy that consumes considerable personal, social and economic costs. It consists of a syndrome of pain, stiffness and symmetrical inflammation of the synovial membrane (synovitis) of freely moveable joints such as the knee (diarthrodial joints). Although the etiology of rheumatoid arthritis is unclear, the disease is char. 2016. Nogueira, Eugenia; Gomes, Andreia; Preto, Ana; Cavaco-Paulo, Artur; Nogueira, E.; Gomes, Andreia C. http://hdl.handle.net/1822/48146.
    10.2174/092986732366616031612506
  11. Albumin-based nanodevices as drug carriers. Nanomedicine, the application of nanotechnology to medicine, is being increasingly used to improve and exploit the advantages of efficient drug delivery. Different nanodevices have been developed in recent years, among them protein-based nanoparticles which have gained considerable interest. Albumin is a versatile protein carrier with several characteristics that make it an ideal candidate for dru. 2016. Loureiro, Ana Isabel Sá; Azóia, Nuno G.; Gomes, Andreia C.; Cavaco-Paulo, Artur; Loureiro, A.; Azoia, N.G.; Gomes, A.C.; Cavaco-Paulo, A.. http://hdl.handle.net/1822/43314.
    10.2174/1381612822666160125114900
  12. Hydrophobic surface functionalization of lignocellulosic jute fabrics by enzymatic grafting of octadecylamine. Enzymatic grafting of synthetic molecules onto lignins provides a mild and eco-friendly alternative for the functionalization of lignocellulosic materials. In this study, laccase-mediated grafting of octadecylamine (OA) onto lignin-rich jute fabrics was investigated for enhancing the surface hydrophobicity. First, the lignins in jute fabrics were isolated and analyzed in the macromolecular level b. 2015. Dong, Aixue; Fan, Xuerong; Wang, Qiang; Yu, Yuanyuan; Paulo, Artur Cavaco; Dong, A.; Fan, X.; et al. http://hdl.handle.net/1822/35362.
    10.1016/j.ijbiomac.2015.05.007
  13. Orange IV stabilizes silk fibroin microemulsions. Silk fibroin (SF) is a natural biopolymer that has been extensively studied in various applications due to its impressive mechanical properties and biocompatibility. Recently, SF-based particles have been proposed as controlled drug delivery systems. A new and efficient method to prepare SF microemulsions (SF-MEs) was developed by oil-in-water emulsions using high-pressure homogenization to promot. 2015. Ferreira, A. V.; Volkov, Vadim; Abreu, Ana S.; Azóia, Nuno G.; Botelho, C. M.; Paulo, Artur Cavaco; Ferreira, A.V.; et al. http://hdl.handle.net/1822/35205.
    10.1002/elsc.201400190
  14. Editorial [to Engineering in Life Sciences, 15(6), 2015]. [Excerpt] Biotechnology has become an important area for the production of smart materials under environmentally friendly conditions. On the one hand, microorganisms can produce polymers where novel strategies in biotechnology allow tuning of their composition and consequently their properties. On the other hand, enzymes are increasingly used both to replace toxic chemicals in processing of materi. 2015. Paulo, Artur Cavaco; Ciardelli, Gianluca; Gübitz, Georg M.. http://hdl.handle.net/1822/37209.
    10.1002/elsc.201570063
  15. Improved Poly (D,L-lactide) nanoparticles-based formulation for hair follicle targeting. Objective Hair follicles are widely recognized as the preferential target and site of accumulation for nanoparticles after topical application. This feature is of particular importance for hair cosmetics, having the potential to refine the treatment of several hair follicle-related disorders. The aim of this work was to improve the preparation of Poly (D,L-lactide) (PLA) nanoparticles for in vivo. 2015. Fernandes, Bruno Pacheco; Silva, R.; Ribeiro, Artur J.; Matamá, Maria Teresa; Gomes, A. C.; Paulo, Artur Cavaco; Fernandes, B.; et al. http://hdl.handle.net/1822/35125.
    10.1111/ics.12197
  16. Jute/polypropylene composites: Effect of enzymatic modification on thermo-mechanical and dynamic mechanical properties. In this study, a high-performance composite was prepared from jute fabrics and polypropylene (PP). In order to improve the compatibility of the polar fibers and the non-polar matrix, alkyl gallates with different hydrophobic groups were enzymatically grafted onto jute fabric by laccase to increase the surface hydrophobicity of the fiber. The grafting products were characterized by FTIR. The result. 2015. Ni, Xiaoyan; Dong, Aixue; Fan, Xuerong; Wang, Qiang; Yu, Yuanyuan; Cavaco-Paulo, Artur; Ni, X.; et al. http://hdl.handle.net/1822/38733.
    10.1007/s12221-015-5475-7
  17. Sonochemical and hydrodynamic cavitation reactors for laccase/hydrogen peroxide cotton bleaching. The main goal of this work is to develop a novel and environmental-friendly technology for cotton bleaching with reduced processing costs. This work exploits a combined laccase–hydrogen peroxide process assisted by ultrasound. For this purpose, specific reactors were studied, namely ultrasonic power generator type K8 (850 kHz) and ultrasonic bath equipment Ultrasonic cleaner USC600TH (45 kHz). The. 2014. Gonçalves, Idalina; Martins, Madalena A.; Loureiro, Ana; Gomes, A. C.; Paulo, Artur Cavaco; Silva, Carla Manuela Pereira Marinho da; Gonçalves, I.; et al. http://hdl.handle.net/1822/26648.
    10.1016/j.ultsonch.2013.08.006
  18. Phosphorylation of silk fibroins improves the cytocompatibility of silk fibroin derived materials: a platform for the production of tuneable material. Silk fibroin demonstrates great biocompatibility and is suitable for many biomedical applications, including tissue engineering and regenerative medicine. Current research focuses on manipulating the physico-chemical properties of fibroin, and examining the effect of this manipulation on firobin's biocompatibility. Regenerated silk fibroin was modified by in vitro enzymatic phosphorylation and cas. 2014. Volkov, Vadim; Vasconcelos, Andreia; Sárria, M. P.; Gomes, Andreia; Paulo, Artur Cavaco; Volkov, V.; Vasconcelos, A.; et al. http://hdl.handle.net/1822/31800.
    10.1002/biot.201400302
  19. Gene silencing by siRNA nanoparticles synthesized via sonochemical method. The knowledge that small RNAs can affect gene expression has had a tremendous impact on basic and applied research, and gene silencing is currently one of the most promising new approaches for disease therapy. However, RNAs cannot easily penetrate cell membranes, therefore RNA delivery become one of the major challenges for gene silencing technology. In the current paper we discuss a general appro. 2014. Shimanovich, Ulyana; Munder, A.; Loureiro, Ana; Azóia, Nuno G.; Gomes, Andreia; Paulo, Artur Cavaco; Gedanken, Aharon; et al. http://hdl.handle.net/1822/31685.
    10.4172/2157-7439.1000204
  20. Protein disulphide isomerase-assisted functionalization of proteinaceous substrates. Protein disulphide isomerase (PDI) is an enzyme that catalyzes thiol-disulphide exchange reactions among a broad spectrum of substrates, including proteins and low-molecular thiols and disulphides. As the first protein-folding catalyst reported, the study of PDI has mainly involved the correct folding of several cysteine-containing proteins. Its application on the functionalization of protein-base. 2012. Fernandes, Margarida M.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/22623.
    10.3109/10242422.2012.646657
  21. Laccases stabilization with phosphatidylcholine liposomes. In recent years, there has been an upsurge of interest in enzyme treatment of textile fibres. Enzymes are globular proteins whose catalytic function is due to their three dimensional structure. For this reason, stability strategies make use of compounds that avoid dismantling or distorting protein 3D structures. This study is concerned with the use of microencapsulation techniques to optimize enzy. 2012. Martí, M.; Zille, Andrea; Paulo, Artur Cavaco; Parra, J. L.; Coderch, L.. http://hdl.handle.net/1822/22625.
  22. Protein disulphide isomerase-assisted functionalization of keratin-based matrices. In living systems, protein disulphide isomerase (PDI, EC 5.3.4.1) regulates the formation of new disulphide bonds in proteins (oxidase activity) and catalyzes the rearrangement of non-native disulphide bonds (isomerase activity), leading proteins towards their native configuration. In this study, PDI was used to attach cysteine-containing compounds (CCCs) onto hair, to enhance compound migration w. 2011. Fernandes, Margarida M.; Gomes, A. C.; Vasconcelos, Andreia; Munteanu, Florentina-Daniela; Tzanov, Tzanko; Gonçalves, M. Sameiro T.; End, N.; et al. http://hdl.handle.net/1822/14767.
    10.1007/s00253-011-3194-6
  23. Tailoring elastase inhibition with synthetic peptides. Chronic wounds are the result of excessive amounts of tissue destructive proteases such as human neutrophil elastase (HNE). The high levels of this enzyme found on those types of wounds inactivate the endogenous inhibitor barrier thus, the search for new HNE inhibitors is required. This work presents two new HNE inhibitor peptides, which were synthesized based on the reactive-site loop of the Bowm. 2011. Vasconcelos, Andreia; Azóia, Nuno G.; Carvalho, A. C.; Gomes, A. C.; Guebitz, G. M.; Paulo, Artur Cavaco; Vasconcelos, A.; et al. http://hdl.handle.net/1822/15152.
    10.1016/j.ejphar.2011.05.056
  24. Polyoxometalate/laccase-mediated oxidative polymerization of catechol for textile dyeing. The synergistic effect between polyoxometalates (POMs), namely K5[SiW11VVO40]·11H2O and H5[PMo10 VV2O40]·13H2O and laccase from ascomycete Myceliophthora thermophila has been employed for the first time in oxidative polymerization of catechol. Such a laccase-mediator system allowed the formation of a relatively high molecular weight polycatechol as confirmed by size exclusion chromatography and el. 2011. Kim, Suyeon; Silva, Carla Manuela Pereira Marinho da; Evtuguin, D. V.; Gamelas, José A. F.; Paulo, Artur Cavaco; Kim, S.; Silva, C.; et al. http://hdl.handle.net/1822/17302.
    10.1007/s00253-010-2932-5
  25. Sonoproduction of liposomes and protein particles as templates for delivery purposes. The development of nano and micro delivery systems (DS), so small in size, is growing in importance, such as in drug targeting. In an era where nano is the new trend, micro and nano materials are in the forefront of progress. These systems can be produced by a diversity of methods. However, the use of high-intensity ultrasound offers an easy and versatile tool for nano- and microstructured materia. 2011. Silva, Raquel; Ferreira, Helena; Paulo, Artur Cavaco; Silva, R.; Ferreira, H.; Cavaco-Paulo, A.. http://hdl.handle.net/1822/15303.
    10.1021/bm200658b
  26. Wound dressings for a proteolytic-rich environment. Wound dressings have experienced continuous and significant changes over the years based on the knowledge of the biochemical events associated with chronic wounds. The development goes from natural materials used to just cover and conceal the wound to interactive materials that can facilitate the healing process, addressing specific issues in non-healing wounds. These new types of dressings often. 2011. Vasconcelos, Andreia; Paulo, Artur Cavaco; Vasconcelos, A.; Cavaco-Paulo, A.. http://hdl.handle.net/1822/14753.
    10.1007/s00253-011-3135-4
  27. Attaching different kinds of proteinaceous nanospheres to a variety of fabrics using ultrasound radiation. The application of a rapid, non-destructive, cost-effective technique such as ultrasonic emulsification for the coating of different textiles was explored. The technical benefits for this research were the generation of multifunctional materials and their combinations through environmentally friendly processing technologies. We have shown for the first time that ultrasonic waves can be used to coa. 2010. Angel, U.; Silva, Carla Manuela Pereira Marinho da; Paulo, Artur Cavaco; Gedanken, Aharon; Silva, C.M.; Cavaco-Paulo, A.; Gedanken, A.. http://hdl.handle.net/1822/22567.
    10.1002/ijch.201000054
  28. Polymerization study of the aromatic amines generated by the biodegradation of azo dyes using the laccase enzyme. Four different azo dyes were decolorized (color reduction >90%) by bacteria isolated from a textile wastewater effluent. Dye decolorizing was carried out under microaerobic conditions until completion, after which the aromatic amine concentration was determined. A laccase from Myceliophthora thermophila was used to catalyze coupling reactions of the aromatic amines produced from decolorizing the d. 2010. Franciscon, E.; Piubeli, F.; Fantinatti-Garboggini, F.; Menezes, C. R.; Silva, I. S.; Paulo, Artur Cavaco; Grossman, M. J.; et al. http://hdl.handle.net/1822/14769.
    10.1016/j.enzmictec.2009.12.014
  29. Characterization of thermobifida fusca cutinase-carbohydrate-Binding modube fusion proteins and their potential application in bioscouring. Cutinase from Thermobifida fusca is thermally stable and has potential application in the bioscouring of cotton in the textile industry. In the present study, the carbohydrate-binding modules (CBMs) from T. fusca cellulase Cel6A (CBMCel6A) and Cellulomonas fimi cellulase CenA (CBMCenA) were fused, separately, to the carboxyl terminus of T. fusca cutinase. Both fusion enzymes, cutinase-CBMCel6A and. 2010. Zhang, Yao; Chen, S.; Xu, M.; Paulo, Artur Cavaco; Wu, J.; Chen, J.. http://hdl.handle.net/1822/17295.
  30. Polymerization of lignosulfonates by the laccase-HBT (1-hydroxybenzotriazole) system improves dispersibility. The ability of laccases from Trametes villosa (TvL), Myceliophthora thermophila (MtL), Trametes hirsuta (ThL) and Bacillus subtilis (BsL) to improve the dispersion properties of calcium lignosulfonates 398 in the presence of HBT as a mediator was investigated. Size exclusion chromatography showed an extensive increase in molecular weight of the samples incubated with TvL and ThL by 107% and 572% f. 2010. Prasetyo, E. N.; Kudanga, T.; Østergaard, L.; Rencoret, J.; Gutiérrez, A.; Río, J. C. del; Santos, J. I.; et al. http://hdl.handle.net/1822/14756.
    10.1016/j.biortech.2010.01.048
  31. Expression system of CotA-laccase for directed evolution and high-throughput screenings for the oxidation of high-redox potential dyes. Laccases are useful biocatalysts for many diverse biotechnological applications. In this study we have established efficient and reliable expression systems and high-throughput screenings for the recombinant CotA-laccase from Bacillus subtilis. The expression levels of cotA-laccase were compared in five different Escherichia coli host strains growing in 96-well microtiter plates under different cu. 2009. Brissos, V.; Pereira, Luciana; Munteanu, Florentina-Daniela; Paulo, Artur Cavaco; Martins, L. O.; Pereira, L.; Munteanu, F.-D.; Cavaco-Paulo, A.; Martins, L.O.. http://hdl.handle.net/1822/17277.
    10.1002/biot.200800248
  32. Biodegradation of textile azo dyes by a facultative Staphylococcus arlettae strain VN-11 using a sequential microaerophilic/aerobic process. A facultative Staphylococcus arlettae bacterium, isolated from an activated sludge process in a textile industry, was able to successfully decolourize four different azo dyes under microaerophilic conditions (decolourization percentage >97%). Further aeration of the decolourized effluent was performed to promote oxidation of the degradation products. The degradation products were characterized by. 2009. Franciscon, E.; Zille, Andrea; Dias, G. F.; Menezes, C. R.; Durrant, L. R.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/17320.
    10.1016/j.ibiod.2008.10.003
  33. A novel aryl acylamidase from Nocardia farcinica hydrolyses polyamide. An alkali stable polyamidase was isolated from a new strain of Nocardia farcinica. The enzyme consists of four subunits with a total molecular weight of 190 kDa. The polyamidase cleaved amide and ester bonds of water insoluble model substrates like adipic acid bishexylamide and bis(benzoyloxyethyl)terephthalate and hydrolyzed different soluble amides to the corresponding acid. Treatment of polyami. 2009. Heumann, Sonja; Eberl, A.; Fischer-Colbrie, Gudrun; Pobeheim, Herbert; Kaufmann, F.; Ribitsch, D.; Paulo, Artur Cavaco; et al. http://hdl.handle.net/1822/17322.
    10.1002/bit.22139
  34. Biotransformation of synthetic fibers. Recent studies clearly indicate that the modification of synthetic polymers with enzymes is an environmentally friendly alternative to traditional chemical methods requiring harsh conditions. Some work already performed on polyamide 6.6 (nylon 6.6), polyethyleneterephthalate (PET) and polyacrylonitrile (PAN) revealed that surface functionalization of these materials is a key requirement for an ext. 2008. Silva, Carla Manuela Pereira Marinho da; Paulo, Artur Cavaco. http://hdl.handle.net/1822/13852.
    10.1080/10242420802357845
  35. Enzymatic hydrolysis of PTT polymers and oligomers. Oligomers and polymers (film, fabrics) of the linear aromatic polyester poly(trimethylene terephthalate) (PTT) were treated with polyesterases from Thermomyces lanuginosus, Penicillium citrinum, Thermobifida fusca and Fusarium solani pisi. The cutinase from T. fusca was found to release the highest amounts of hydrolysis products from PTT materials and was able to open and hydrolyse a cyclic PTT di. 2008. Eberl, A.; Heumann, Sonja; Kotek, R.; Kaufmann, F.; Mitscher, S.; Paulo, Artur Cavaco; Gübitz, Georg M.. http://hdl.handle.net/1822/13849.
    10.1016/j.jbiotec.2008.02.015
  36. Bioelectrochemical investigations of aryl-alcohol oxidase from Pleurotus eryngii. Aryl-alcohol oxidase (AAO) electrochemistry studies, using graphite-modified electrodes, are presented for the first time herein. The increase in current upon injection of the analyzed substrate was shown to be approximated by Michaelis–Menten type dependence. The calculated kinetic constants were used to characterize the native (non-mutated) recombinant AAO expressed in Escherichia coli, as well. 2008. Munteanu, Florentina-Daniela; Ferreira, Patrícia; Ruiz-Duenas, Francisco J.; Martínez, Angel T.; Paulo, Artur Cavaco; Munteanu, F.-D.; Ferreira, P.; et al. http://hdl.handle.net/1822/13848.
    10.1016/j.jelechem.2008.02.023
  37. Enzymatic surface hydrolysis of PET enhances bonding in PVC coating. The effect of polyesterase preparations from Thermomyces lanuginosus and Beauveria brongniartii on the hydrophilicity of PET materials was assessed. As a result of polyesterase treatment the hydrophilicity of PET fabrics was increased by up to 8 cm in terms of rising height with increases in surface tension from 6.2 mNm (heat-inactivated control samples) to above 8 mNm. Both enzymes were able to i. 2008. Almansa, E.; Heumann, S.; Eberl, A.; Fischer-Colbrie, Gudrun; Martinkova, L.; Marek, J.; Paulo, Artur Cavaco; Guebitz, G. M.. http://hdl.handle.net/1822/16432.
    10.1080/10242420802357613
  38. Surface hydrolysis of polyamide with a new polyamidase from Beauveria brongniartii. Twelve fungi were screened for the potential of their extracellular enzymes to increase the hydrophilicity of polyamide (PA) materials. The most pronounced increase in hydrophilicity was found for enzymes from Beauveria brongniartii and B. bassiana. The 55 kDa polyamidase from B. brongniartii was purified using ultrafiltration, anion exchange chromatography and size exclusion chromatography. This. 2008. Almansa, Eva; Heumann, Sonja; Eberl, A.; Kaufmann, F.; Paulo, Artur Cavaco; Gübitz, Georg M.; Almansa, E.; et al. http://hdl.handle.net/1822/17287.
    10.1080/10242420802323433
  39. Laccases for enzymatic colouration of unbleached cotton. The concept presented in this paper is the utilisation of the natural flavonoids present in cotton as anchors to attach other phenolic compounds to the fiber surface. Laccase can catalyze the oxidation of flavonoids in solution producing quinones that can be further polymerised and grafted onto surface of the cotton providing yellow to brown colouration, depending on the external flavonoids used a. 2007. Kim, Suyeon; Moldes, Diego; Paulo, Artur Cavaco. http://hdl.handle.net/1822/13843.
    10.1016/j.enzmictec.2007.01.002
  40. Enzymatic reduction of azo and indigoid compounds. A customer- and environment-friendly method for the decolorization azo dyes was developed. Azoreductases could be used both to bleach hair dyed with azo dyes and to reduce dyes in vat dyeing of textiles. A new reduced nicotinamide adenine dinucleotide-dependent azoreductase of Bacillus cereus, which showed high potential for reduction of these dyes, was purified using a combination of ammonium sul. 2007. Pricelius, S.; Held, C.; Murkovic, M.; Bozic, M.; Kokol, V.; Paulo, Artur Cavaco; Gübitz, Georg M.. http://hdl.handle.net/1822/13850.
    10.1007/s00253-007-1165-8
  41. Laccase immobilization on enzymatically functionalized polyamide 6,6 fibres. Polyamide matrices, such as membranes, gels and non-wovens, have been applied as supports for enzyme immobilization, although in literature the enzyme immobilization on woven nylon matrices is rarely reported. In this work, a protocol for a Trametes hirsuta laccase immobilization using woven polyamide 6,6 (nylon) was developed. A 24 full factorial design was used to study the influence of pH, spac. 2007. Silva, Carla Manuela Pereira Marinho; Silva, Carla J. S. M.; Zille, Andrea; Gübitz, Georg M.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/13847.
    10.1016/j.enzmictec.2007.07.010
  42. Enzymatic synthesis of Tinuvin. Coupling of 3-(3-tert-butyl-4-hydroxyphenyl) propionic acid methylester to 1H-benzotriazole using a laccase from Trametes hirsuta was studied. The potentially resulting coupling product Tinuvin 1130 is an important UV-absorber used in polymer based materials. Oxidation of the phenol by the laccase led to homomolecular coupling reactions while the laccase did not attack 1H-benzotriazole. Due to the. 2007. Schroeder, M.; Pereira, Luciana; Rodríguez Couto, S.; Erlacher, Angelika; Schoening, K.-U.; Paulo, Artur Cavaco; Guebitz, G. M.. http://hdl.handle.net/1822/13562.
    10.1016/j.enzmictec.2006.11.026
  43. Influence of mechanical agitation on cutinases and protease activity towards polyamide substrates. Two polyamide 6,6 substrates with different constructions, namely a model substrate and a fabric, were hydrolyzed using native cutinase and L182A cutinase mutant (from Fusarium solani pisi) and a protease (subtilisin from Bacillus sp.). The catalytic efficiency of these enzymes, measured in terms of hydrolysis products release, was measured for both substrates and the protease released five times. 2007. Silva, Carla Manuela Pereira Marinho da; Araújo, Rita; Casal, Margarida; Gübitz, Georg M.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/13141.
    10.1016/j.enzmictec.2006.09.001
  44. Stability and decolourization ability of trametes villosa laccase in liquid ultrasonic fields. We report in this study that the sonication of laccase from Trametes villosa and bovine serum albumin promotes the formation of protein aggregates with high molecular weight. The formation of aggregates leads to the deactivation of the enzyme, fact that was confirmed by the analysis of the enzyme stability (half-life time) upon ultrasound treatment. This inactivation was mainly caused by the radic. 2007. Basto, Carlos; Silva, Carla J. S. M.; Gübitz, Georg M.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/13071.
    10.1016/j.ultsonch.2006.07.005
  45. Enzymatic reduction and oxidation of fibre-bound azo-dyes. A new customer and environmental friendly method of hair bound dye decolouration was developed. Biotransformation of the azo-dyes Flame Orange and Ruby Red was studied using different oxidoreductases. The pathways of azo dye conversion by these enzymes were investigated and the intermediates and metabolites were identified and characterised using UV–vis spectroscopy, high-performance liquid chroma. 2007. Pricelius, S.; Held, C.; Sollner, S.; Deller, S.; Murkovic, M.; Ullrich, R.; Hofrichter, M.; et al. http://hdl.handle.net/1822/13559.
    10.1016/j.enzmictec.2006.11.004
  46. Staining of wool using the reaction products of ABTS oxidation by Laccase : synergetic effects of ultrasound and cyclic voltammetry. The effects of ultrasound on 2,2'-Azinobis(3-ethylbenzothiazoline-6-sulfonate) enzymatic oxidation by laccase (Trametes villosa) has been studied by means of cyclic voltammetry. The reaction was allowed to proceed in the presence of a piece of wool and the coloration depth of the wool fabric was measured by means of K/S. It was observed that cyclic voltammetry is influenced the dyeing process and. 2007. Munteanu, Florentina-Daniela; Basto, Carlos; Gübitz, Georg M.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/13123.
    10.1016/j.ultsonch.2006.07.008
  47. Effect of the agitation on the adsorption and hydrolytic efficiency of cutinases on polyethylene terephthalate fibres. The effect of agitation on adsorption, desorption and hydrolytic efficiency of a native and a genetically modified cutinase (L182A) on polyethylene terephthalate fibres is reported in this paper. The effect of mechanical agitation was studied using a shaker bath with orbital agitation and a Rotawash machine with vertical agitation with and without extra steel discs inside the reaction pots. The re. 2007. O'Neill, Jaime Alexandre Antunes; Araújo, Rita; Casal, Margarida; Gübitz, Georg M.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/13844.
    10.1016/j.enzmictec.2007.02.012
  48. Enzymatic polymerization on the surface of functionalized cellulose fibers. Enzymatic coating of functionalized cellulose fibers with catechol was performed in the presence of Trametes hirsuta laccase. Cellulose functionalization was done by covalent fixation of aromatic amines onto the cellulose surface using a dyeing procedure with C.I. Reactive Black 5 (RB5) followed by reduction with sodium hydrosulfite. Cellulase enzymes were used on coated and control samples to obt. 2007. Kim, Suyeon; Zille, Andrea; Murkovic, M.; Guebitz, G. M.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/13817.
    10.1016/j.enzmictec.2007.01.001
  49. Sono-enzymatic polymerization of catechol. The potential of laccase enzymes for polymerizing, crosslinking and functionalizing various compounds was studied extensively and increasing interest has been focused on the application of this enzyme as a new biocatalyst in organic synthesis.[1-6] Laccases (EC 1.10.3.2) are a class of multi-copper-containing oxidoreductase enzymes able to catalyze the transformation of various aromatic compounds,. 2006. Fernandes, Margarida M.; Basto, Carlos; Zille, Andrea; Munteanu, Florentina-Daniela; Gübitz, Georg M.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/24826.
  50. Specificities of a chemically modified laccase from trametes hirsuta on soluble and cellulose-bound substrates. Laccases could prevent fabrics and garments from re-deposition of dyes during washing and finishing processes by degrading the solubilized dye. However, laccase action must be restricted to solubilized dye molecules thereby avoiding decolorization of fabrics. Chemical modification of enzymes can provide a powerful tool to change the adsorption behaviour of enzymes on water insoluble polymers. Poly. 2006. Schroeder, M.; Heumann, Sonja; Silva, Carla J. S. M.; Paulo, Artur Cavaco; Gübitz, Georg M.; Heumann, S.; Silva, C.J.S.M.; Cavaco-Paulo, A.; Guebitz, G.M.. http://hdl.handle.net/1822/12948.
    10.1007/s10529-006-9052-4
  51. The effect of additives and mechanical agitation in surface modification of acrylic fibres by cutinase and esterase. The surface of an acrylic fibre containing about 7% of vinyl acetate was modified using Fusarium solani pisi cutinase and a commercial esterase, Texazym PES. The effect of acrylic solvents and stabilising polyols on cutinase operational stability was studied. The half-life time of cutinase increased by 3.5-fold with the addition of 15% N,N-dimethylacetamide (DMA) and by 3-fold with 1M glycerol. Th. 2006. Matamá, Maria Teresa; Vaz, F.; Gübitz, Georg M.; Paulo, Artur Cavaco; Matamá, T.; Gübitz, G.M.; Cavaco-Paulo, A.. http://hdl.handle.net/1822/12963.
    10.1002/biot.200600034
  52. Degradation of azo dyes by trametes villosa laccase over long periods of oxidative conditions. Trametes villosa laccase was used for direct azo dye degradation, and the reaction products that accumulated after 72 h of incubation were analyzed. Liquid chromatography-mass spectrometry (LC-MS) analysis showed the formation of phenolic compounds during the dye oxidation process as well as a large amount of polymerized products that retain azo group integrity. The amino-phenol reactions were als. 2005. Zille, Andrea; Górnacka, B.; Rehorek, A.; Paulo, Artur Cavaco; Zille, A.; Gornacka, B.; Cavaco-Paulo, A.. http://hdl.handle.net/1822/4351.
    10.1128/AEM.71.11.6711-6718.2005
  53. Azo reductase activity of intact saccharomyces cerevisiae cells Is dependent on the fre1p component of plasma membrane ferric reductase. Unspecific bacterial reduction of azo dyes is a process widely studied in correlation with the biological treatment of colored wastewaters, but the enzyme system associated with this bacterial capability has never been positively identified. Several ascomycete yeast strains display similar decolorizing behaviors. The yeastmediated process requires an alternative carbon and energy source and is ind. 2005. Ramalho, Patrícia A.; Paiva, Sandra; Paulo, Artur Cavaco; Casal, Margarida; Cardoso, M. Helena; Ramalho, Maria Teresa; Ramalho, P.A.; et al. http://hdl.handle.net/1822/2679.
    10.1128/AEM.71.7.3882-3888.2005
  54. Biotransformation of phenolics with laccase containing bacterial spores. Treatment of effluents containing phenols such as textile dyes with fungal laccases is usually limited to the acid to neutral pH range and moderate temperatures. Here we demonstrate for the first time that spore-bound laccases which are stable at high temperatures and pH values can be used for phenolic dye decolorisation. Laccase containing spores from Bacillus SF were immobilized on alumina pelle. 2005. Held, C.; Kandelbauer, A.; Schroeder, M.; Paulo, Artur Cavaco; Gübitz, Georg M.; Cavaco-Paulo, A.; Guebitz, G.M.. http://hdl.handle.net/1822/12457.
    10.1007/s10311-005-0006-1
  55. Environmentally friendly bleaching of cotton using laccases. A new strain of Trametes hirsuta was found to oxidize various cotton flavonoids. Here we show that laccases of this organism were responsible for oxidation of the flavonoids morin, luteolin, rutin and quercetin. Out of two laccases produced by T. hirsuta (60.7 and 51.0 kDa) the more prominent 60.7 kDa laccase was purified and showed Km and kcat values of 75.5, 20.9 and 49.4 µM and 72.5, 96.3 and 3. 2005. Pereira, Luciana; Bastos, C.; Tzanov, Tzanko; Paulo, Artur Cavaco; Gübitz, Georg M.; Pereira, L.; Tzanov, T.; Cavaco-Paulo, A.; Guebitz, G.M.. http://hdl.handle.net/1822/12733.
    10.1007/s10311-005-0004-3
  56. New enzymes with potential for PET surface modification. This work describes newly isolated organisms and their potential to modify the surface of polyethylene terephthalate (PET). Out of the different screening processes, four bacterial and five fungal strains were isolated. A PET model substrate was synthesized (bis (benzoyloxyethyl) terephthalate) and used in the screening process, mimicking the polymer in its crucial properties and having the advant. 2004. Fischer-Colbrie, Gudrun; Heumann, Sonja; Liebminger, Stefan; Almansa, Eva; Paulo, Artur Cavaco; Fischer-Colbrie, G.; Heumann, S.; et al. http://hdl.handle.net/1822/2653.
    10.1080/10242420400024565
  57. Monitoring biotransformations in polyamide fibres. The enzymatic hydrolysis of polyamide fibres yields amino and carboxylic groups. These groups can be found in solution treatments as polyamide monomers and soluble oligomers. The amino groups can also be found at the surface of the fibres as end group chains. In this paper we report two methods to quantify the formation of these groups as a result of the enzymatic action. Soluble amino groups can. 2004. Silva, Carla Manuela Pereira Marinho da; Paulo, Artur Cavaco; O'Neill, Jaime Alexandre Antunes. http://hdl.handle.net/1822/2629.
    10.1080/10242420400025828
  58. An acid-stable laccase from sclerotium rolfsii with potential for wool dye decolourization. The plant pathogen basidiomycete S. rolfsii secretes two laccases (SRL1 and SRL2) with molecular weights of 55 and 86 kDa, respectively. Laccase production was shown to be inducible by the addition of 2,5-xylidine to the cultural media. After treatment with a combination of chitinase and -1,3-glucanase, two different laccases were isolated from the sclerotia depending on the stage of sclerotia dev. 2003. Ryan, S.; Schnitzhofer, W.; Tzanov, Tzanko; Paulo, Artur Cavaco; Tzanov, T.; Cavaco-Paulo, A.; Gübitz, G.M.. http://hdl.handle.net/1822/2392.
    10.1016/S0141-0229(03)00162-5
  59. Effect of purified trichoderma reesei cellulases on formation of cotton powder from cotton fabric. The mode of action of monocomponent purified Trichoderma reesei cellobiohydrolases (CBHI and CBHII) and endoglucanases (EGI and EGII) on cotton fabrics was studied by analyzing the weight loss of the fabric, the reducing sugars, the soluble oligosaccharides and the molecular weight of the cotton powder formed. The impact of mechanical action on these factors was also evaluated. EGI and EGII releas. 2003. Heikinheimo, Lea; Miettinen-Oinonen, Arja; Paulo, Artur Cavaco; Heikinheimo, L.; Miettinen-Oinonen, A.; Cavaco-Paulo, A.; Buchert, J.. http://hdl.handle.net/1822/1983.
    10.1002/app.12868
  60. New substrates for reliable enzymes: enzymatic modification of polymers. Recent studies clearly indicate that the modification of synthetic and natural polymers with enzymes is an environmentally friendly alternative to chemical methods using harsh conditions. New processes using lipases, proteases, nitrilases and glycosidases have been developed for the specific non-destructive functionalization of polymer surfaces. The specificity of enzymes has also been exploited i. 2003. Gübitz, Georg M.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/2628.
  61. An immobilised catalase peroxidase from the alkalothermophilic bacillus SF for the treatment of textile-bleaching effluents. A catalase peroxidase (CP) from the newly isolated Bacillus SF was used to treat textile-bleaching effluents. The enzyme was stable at high pH values and temperatures, but was more sensitive to deactivation by hydrogen peroxide than monofunctional catalases. Based on the Michaelis-Menten kinetics of the CP, a model was developed to describe its deactivation characteristics. The enzyme was immobili. 2002. Fruhwirth, Gilbert Otto; Paar, Andreas; Gudelj, Marinka; Paulo, Artur Cavaco; Robra, Karl-Heinz; Gübitz, Georg M.. http://hdl.handle.net/1822/2391.
    10.1007/s00253-002-1127-0
  62. Treatment of bleaching baths for reuse in dyeing with immobilized thermoalkalistable catalases. 2002. Paar, Andreas; Gudelj, Marinka; Beurer, Ivo; Robra, Karl-Heinz; Paulo, Artur Cavaco; Paar, A.; Gudelj, M.; et al. http://hdl.handle.net/1822/4352.
  63. Possibilities for recycling cellulases after use in cotton processing. 2002. Azevedo, Helena S.; Bishop, David; Paulo, Artur Cavaco. http://hdl.handle.net/1822/2396.
  64. Die verminderung von indigobackstaining in einem nachwaschschritt. 2001. Andreaus, J.; Campos, R.; Cavaco-Paulo, A.. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035476769&partnerID=MN8TOARS.
  65. Dyeing in catalase-treated bleaching baths. Hydrogen peroxide is commonly used bleaching agent for textiles. Dyeing after bleaching requires repeatedly rinsing the textile material to remove any residue of peroxide that might be harmful to the dyes either in solution or on the fabric. 1 , 2 Even this washing process cannot guarantee the complete removal of the peroxide. Contemporary biotechnology offers the opportunity to reduce the large w. 2001. Tzanov, T.; Costa, S.; Guebitz, G.M.; Cavaco-Paulo, A.; Giibitz, G.M.; Tzanov, Tzanko; Costa, Silgia; Paulo, Artur Cavaco; Gübitz, Georg M.. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035034007&partnerID=MN8TOARS.
    10.1111/j.1478-4408.2001.tb00327.x
  66. Reduction of indigo backstaining by post-washing | Die Verminderung von Indigobackstaining in einem Nachwaschschritt. 2001. Andreaus, J.; Campos, R.; Cavaco-Paulo, A.. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034759569&partnerID=MN8TOARS.
  67. Effect of temperature and bath composition on the dyeing of cotton with catalase-treated bleaching effluent. Conventional rinsing to remove residual hydrogen peroxide after the bleaching of cotton fabric can be replaced by enzymatic cleaning using catalases. Our previous study showed that dyeing in such catalase-treated bleaching baths results in a shade change on the dyed fabrics. The aim of this present study was to investigate the reasons for the unacceptable colour differences of the dyed fabrics. Ex. 2001. Tzanov, T.; Costa, S.; Guebitz, G.M.; Cavaco-Paulo, A.; Tzanov, Tzanko; Costa, Silgia; Gübitz, Georg M.; Paulo, Artur Cavaco. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034926324&partnerID=MN8TOARS.
    10.1111/j.1478-4408.2001.tb00057.x
  68. Enzymatic treatment of acrylic fibers and granulates. 2001. Tauber, M.; Gübitz, G.; Cavaco-Paulo, A.. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035455629&partnerID=MN8TOARS.
  69. A catalase-peroxidase from a newly isolated thermoalkaliphilic Bacillus with potential for the treatment of textile bleaching effluents. 2001. Gudelj, Marinka; Fruhwirth, Gilbert Otto; Paar, Andreas; Lottspeich, Fritz; Robra, Karl-Heinz; Paulo, Artur Cavaco; Gübitz, Georg M.. http://hdl.handle.net/1822/1980.
  70. The role of Trichoderma reesei cellulases in cotton finishing. Knitted and woven cotton fabrics were treated with a mono component Trichoderma reesei endoglucanase (EGII) and with experimental Trichoderma cellulase mixtures containing different cellulase profiles. The cellulase action was evaluated by measuring weight loss, pilling, and bursting strength. Of the experimental mixtures, Cellulase F, being an EGII-enriched preparation, was the best mixture to ob. 2001. Miettinen-Oinonen, Arja; Heikinheimo, Lea; Buchert, Johanna; Morgado, José; Almeida, Luís de; Ojapalo, P.; Paulo, Artur Cavaco; et al. http://hdl.handle.net/1822/12714.
  71. Indigo degradation with laccases from Polyporus sp. and Sclerotium rolfsii. The degradation of the textile dye indigo with purified laccases from the fungi Trametes hirsuta (THL1 and THL2) and Sclerotium rolfsii (SRL1) was studied. All laccases were able to oxidize indigo yielding isatin (indole-2,3-dione), which was further decomposed to anthranilic acid (2-aminobenzoic acid). Based on the oxygen consumption rate of the laccases during indigo degradation, a potential mec. 2001. Campos, Rui; Robra, K. H.; Paulo, Artur Cavaco; Schneider, Monika; Gübitz, Georg M.; Kandelbauer, A.; Campos, R.; et al. http://hdl.handle.net/1822/12716.
    10.1177/004051750107100509
  72. Reduction of indigo backstaining by post-washing. The undesired redeposition of indigo during the enzymatic ageing of denim garments with cellulases is a problem widely known in industrial laundries. Today, the usual procedure carried out to reduce the undesired side-effect is post-washing, but so far little information can be found in literature about efficient methods to achieve a maximum blue-white contrast in denim garments. This article deal. 2001. Andreaus, Juergen; Campos, Raquel de; Paulo, Artur Cavaco. http://hdl.handle.net/1822/12729.
  73. Improving dimensional stability of cotton fabrics with cellulase enzymes. 2001. Paulo, Artur Cavaco. http://hdl.handle.net/1822/12713.
    10.1177/004051750107100916
  74. Enzymatic treatment of lyocell - clarification of depilling mechanisms. We have characterized cellulose from lhe original structure of a lyocell fabric, from pills mechanically removed from lhe surface with a razor blade and from cellulase depilling process We find that cellulases first attack the cellulose from the microfibrils on the surface of the fabric because they are more exterrna!!y exposed lhan the cellulose of lhe original fabric structure and have the same. 2000. Cavaco-Paulo, A.; Morgado, J.; Rousselle, M.-A.; Morgado, José; Paulo, Artur Cavaco; Rousselle, Marie-Alice. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033838362&partnerID=MN8TOARS.
    10.1177/004051750007000807
  75. Enzymatic decolorization of textile dyeing effluents. Commercial azo, triarylmethane, antraquinonic, and indigoid textile dyes are efficiently decolorized with enzyme preparations from Pleuratus ostreatus, Schizophyllum commune, Neurospora crassa, Polvporus sp., Sclerotium rolfsii, Trametes villosa, and Myceliophtora thermophila. The nature of substituents on the dyes' benzene rings influences enzyme activity, and hydroxyl and amino groups enhance de. 2000. Abadulla, Ellias; Silva, Luísa M.; Paulo, Artur Cavaco; Robra, K. H.; Gübitz, Georg M.; Abadulla, E.; Robra, K.-H.; et al. http://hdl.handle.net/1822/12715.
    10.1177/004051750007000506
  76. Influence of cellulases on indigo backstaining. We have found that increasing concentrations of fungal cellulases on a fabric decrease indigo staining levels. Deletion of the cellulose binding domains (CBD) from either bacterial or fungal cellulases decreases indigo staining levels and generally causes less backstaining than the entire enzyme. Increasing the concentration of cellulases with a CBD of family I on fabric decreases indigo staining,. 2000. Andreaus, Juergen; Campos, Raquel de; Gübitz, Georg M.; Paulo, Artur Cavaco; Andreaus, J.; Campos, R.; Gübitz, G.; Cavaco-Paulo, A.. http://hdl.handle.net/1822/12697.
    10.1177/004051750007000711
  77. Polyoxometalates as promoters of laccase-assisted reactions. A synergistic effect of polyoxometalate and laccase benzenediol:oxygen oxidoreductase, EC 1.10.3.2 has been observed in the aerobic oxidation of a hydrazonaphthalene type colorant. The considerable increase in the decolorization rate of Solophenyl Blue GL dye with the new catalytic system composed by laccase and heptamolybdopentovanadophosphate heteropolyanion, when compared with the treatment wit. 2000. Carneiro, Andrea; Abreu, Ana S.; Evtuguin, D. V.; Neto, C. Pascoal; Gübitz, Georg M.; Paulo, Artur Cavaco. http://hdl.handle.net/1822/2618.
    10.1016/S1381-1177(00)00006-0
  78. Indigo-cellulase interactions. We have studied the affinity of cellulases from different fungal origins for insoluble indigo dye. Adsorption studies have shown that "acid cellulases" from Trichoderma reesei have a higher affinity for indigo dye than "neutral cellulases" of Humicola insolens. The particle size of indigo dye agglomerates is influenced by cellulase origin and concentra tion. Evidence shows that the nonpolar residu. 2000. Campos, Raquel de; Andreaus, Juergen; Gübitz, Georg M.; Paulo, Artur Cavaco; Campos, R.; Cavaco-Paulo, A.; Andreaus, J.; Gübitz, G.. http://hdl.handle.net/1822/12695.
    10.1177/004051750007000610
  79. Hydrolysis of cotton cellulose by engineered cellulases from Trichoderma reesei. We have characterized the activities of TC, EG-rich, and CBH-rich cellulases from T. reesei and have shown that their activities towards cotton fabrics are influenced by ionic strength and adsorbed ionic species as well as by temperature and pH. Adsorption and kinetic experiments confirm that increasing mechanical agitation favors EG attack by greatly increasing the availability of sites for EG ad. 1998. Paulo, Artur Cavaco; Almeida, Luís de; Bishop, David; Cavaco-Paulo, A.; Almeida, L.; Bishop, D.. http://hdl.handle.net/1822/5614.
  80. Indigo backstaining during cellulase washing. We have attempted to understand the mechanisms of indigo backstaining during enzyme stone washing by separately analyzing dye staining levels on different cotton surfaces during the process. The high ability of the cellulase enzyme protein to bind to cotton cellulose is the major cause of backstaining. Further studies of commercial cellulases show that the pH of maximum cellulase activity may not. 1998. Paulo, Artur Cavaco; Morgado, José; Almeida, Luís de; Kilburn, Douglas; Cavaco-Paulo, A.; Morgado, J.; Almeida, L.; Kilburn, D.. http://hdl.handle.net/1822/5616.
    10.1177/004051759806800602
  81. Effects of agitation and endoglucanase pretreatment on the hydrolysis of cotton fabrics by a total cellulase. We have attempted to clarify the effects of low and high levels of mechanical agitation on the cellulolytic activity of a pure endoglucanase (EG) and a total cellulase mixture (TC) on scoured and bleached cotton fabric, along with the effect of EG pretreatment on subsequent treatments with TC. Methods used to follow the progress of fabric treatments include weight loss, breaking load loss, bending. 1996. Paulo, Artur Cavaco; Almeida, Luís de; Bishop, David; Cavaco-Paulo, A.; Almeida, L.; Bishop, D.. http://hdl.handle.net/1822/4403.
    10.1177/004051759606600501
  82. Cellulase activities and finishing effects. Cellulase enzymes are usually characterized by evaluation of their activities towards different forms of cellulose and their derivatives. For textile applications, it was suggested thet the comparative evaluation should also include the measurement of the activities in tests that simulate the large scale treatments with different degrees of mechanical agitation. Comparisons were made between three. 1996. Paulo, Artur Cavaco; Almeida, Luís de; Bishop, David. http://hdl.handle.net/1822/4398.
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