I obtained my PhD in Human Biology in 2010 at the University of Porto. Between 2011 and 2013, I was a postdoc at Dr. Haigis lab at Massachusetts General Hospital/Harvard Medical School, USA. Since then, I have been an independent researcher at i3S/IPATIMUP. In the meantime, I was a mother of three children (2012, 2017, 2020). My h-index is 20 (Google Scholar). I published 31 papers in intl. journals aproximatly 2300 citations, indicating a considerable impact in my field. I was the 1st author in 9 papers and the senior in 2. I co-authored 7 book chapters (5 as senior author). 21/31 studies were published in Q1 journals, including Journal of Clinical Oncology, Cancer Discovery, Gastroenterology, Cancer Research, Oncogene, among others. In my PhD, I characterized gastrointestinal cancers regarding alterations in the KRAS-MAPK and PI3K pathway. I was the first to describe and functionally characterize MLK3 mutations in gastrointestinal cancers; I showed that different subsets of gastrointestinal cancers differ not only in the mutant genes but also on the mutations found within the same gene. As a Postdoc, I worked on the functional characterization of RAS mutations in colorectal cancer, acquiring skills in in vitro and in vivo models highly relevant to my current research. In 2014, I established myself as an independent researcher. I currently lead a research line and team composed by 7 members, studying the crosstalk between cancer cells and tumour microenvironment components such as fibroblasts and immune cells, and focusing on how KRAS, BRAF and PIK3CA oncogenic signalling affects these interactions. I aim to determine how oncogenic signalling affects these interactions, and how this crosstalk impacts disease progression and resistance to therapy. I am also interested in the development of novel therapies and on drug repurposing for cancer treatment. As an independent researcher, I published 2 papers as senior author (in Cancer Research and Cancers), 4 papers resulting from collaborations and 3 book chapters. Two additional papers as senior author were provisionally accepted at Cancers and at Int J Cancer . My team work was already awarded 4 prizes. I have actively participated in technology transfer and entrepreneurship programs to improve my skills on how to translate basic scientific knowledge into meaningful assets for patients and for the society. From 2014 onwards, I supervised 2 junior students, 1 visiting MSc student, 4 MSc students, 3 intl. visiting students (2 PhD and 1 BSc), and 3 research fellows (currently PhD students under my supervision). Currently, I mentor 2 Junior Researchers (postdoc level), supervise 4 PhD students and 1 MSc student, and co-supervise 2 PhD students and 2 MSc student. Since 2014, I obtained ¿226k in salary grants, ~¿305k as PI in three research grants, and ~¿365k as co-PI and ¿19k as team member. Since 2014, I have been establishing an intl. and multidisciplinary network of collaborators composed of basic scientists from life sciences, chemistry, pharmacology and also clinicians to support and enrich my research activities. My work has been nationally and internationally recognised through invited (6) or selected (2) presentations in scientific meetings, invitations to review for >20 renown journals and for funding agencies (2), participation in scientific juris (8), invitation to guest two special issues at Cells and to be a review editor at Frontiers in Gastroenterology, section Gastroenterology and Cancer, and to be a member of the scientific committee in 1 national and 1 international scientific meeting.