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Rosa Resende is Biologist (1998), Master in Cell Biology (2002) and received, in 2008, her PhD in Biomedical Sciences from the Faculty of Medicine, University of Coimbra (UC). In 2005 she did a scientific training (6 months) at the University of California (UCLA), USA. After her PhD she had 3 children that impacted her scientific productivity. She is currently doctorate researcher at the Cell Signaling and Metabolism group (Endoplasmic reticulum (ER) stress response and ER-mitochondria axis research line) from the Center for Neuroscience and Cell Biology (CNC), which integrates the Center for Innovative Biomedicine and Biotechnology (CiBB) at UC. Her research has been focused on the study of the cellular and molecular mechanisms of neurodegenerative disorders such as Alzheimer disease and psychiatry disorders such as bipolar disorder and schizophrenia, focusing on disturbances of ER-mitochondria contacts and on pathological deregulation of cellular and organelle stress responses and aiming the discovery of new targets for therapeutic intervention. Due to her participation in several funded projects, R Resende published 28 peer-reviewed papers, the majority in international quartile 1 (Q1) journals and one book chapter. In addition, she is inventor of 2 patents, 1 presently under evaluation, demonstrating the relevance of her research in knowledge transfer promotion. She The scientific impact of her research is reflected in the H index (17) and high number of citations (more than 1500; Web of Science). Two of her papers are top 10 and one top 5 (NIH percentile). She is a reviewer editor in several scientific journals, and guest editor of one ongoing and one concluded special issues. The articles published under the special issue were compiled in a recently published e-book. In 2017, the project she was developing was awarded with the Bolsa Edgar Cruz e Silva prize 2017 funded by GEECD and SCML. She supervised Master thesis (3 concluded) and students from UC 1st cycle studies (4 concluded). Furthermore, she has been involved in the laboratory training of several post graduate students in collaboration with Master and PhD Programs as well as research fellows. She was main arguer of 7 MSc theses, 1 PhD project (BEB) and of 1 Bachelor Degree Internship. She has reviewed papers for several scientific journals and evaluated research proposals from international institutions, namely Italian Ministry of Health and BRACE (UK). To increase her scientific and technical knowledge, she attended many post-graduate courses/workshops at different national and international universities and research institutes of which she highlights the Course in Laboratory Animal Science (Accredited by FELASA, category C). She has also collaborated on several theoretical and practical classes of the Doctoral Programme in Health Sciences, Master in Biomedical Research, Master in Molecular and Translational Neuroscience and Integrated Masters in Biomedical Engineering and Medicine from the UC. She was invited speaker and/or co-authored more than 30 oral and 50 poster communications in (inter)national scientific meetings. Furthermore, she has been actively enrolled in several science outreach projects and activities (member of the organization committee or collaborator), namely Brain Awareness Week, Ciencia Viva, internships during Summer Holidays, and Portuguese Science and Technology Week and in 25º Concurso Jovens Cientistas as jury member. She have also participated in audiovisual material production to boost public awareness to psychiatry diseases such as BD and SCZ, and AD namely, a comic strip, a newspaper column, and interviews.
Identificação

Identificação pessoal

Nome completo
Rosa Maria Branco de Matos Costa Resende

Nomes de citação

  • Resende, Rosa

Identificadores de autor

Ciência ID
AF13-16A8-6B2D
ORCID iD
0000-0002-0504-5756
Researcher Id
F-4610-2010

Domínios de atuação

  • Ciências Médicas e da Saúde - Medicina Básica - Neurociências

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1) Utilizador proficiente (C1)
Formação
Grau Classificação
2008
Concluído
Biomedical Sciences (Doutoramento)
Universidade de Coimbra Faculdade de Medicina, Portugal
"Neurotoxicity induced by amyloid-beta peptide. The role of different peptide assemblies" (TESE/DISSERTAÇÃO)
Aprovada por unanimidade com louvor e distinção
2002
Concluído
Cell Biology (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Effect of Serine protease from Parietaria judaica pollen in pulmonary epithelium" (TESE/DISSERTAÇÃO)
Very good
1998
Concluído
Biology (Licenciatura)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
"Anticorpos anti-cardosina A no controlo de qualidade de queijos produzidos com flor de cardo" (TESE/DISSERTAÇÃO)
15 Valores (0-20) Good
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2019/01/04 - Atual Investigador Contratado (Investigação) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
(...)
Projetos

Bolsa

Designação Financiadores
2017 - 2018 New BACE1 inhibitors for the treatment of Alzheimer's disease: an approach for the development of effective and safe substrate-selective inhibitors.
NA
Investigador Pós-doutorado
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Santa Casa da Misericórdia de Lisboa
Concluído
2015 - 2018 Exosome-mediated glia-neuronal crosstalk upon inflammasome activation in AD
SFRH/BPD/101028/2014
Bolseiro de Pós-Doutoramento
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2009 - 2015 BETA-AMYLOID AND ALPHA-SYNUCLEIN: TWO PROTEINS, ONE PATHWAY TO ALZHEIMER DISEASE?
SFRH/BPD/34712/2007
Bolseiro de Pós-Doutoramento
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
2003 - 2008 Neurotoxicity induced by amyloid-beta peptide. The role of different peptide assemblies.
SFRH/BD/11005/2002
Bolseiro de Doutoramento
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
1999 - 2002 Effect of Serine protease from Parietaria judaica pollen in pulmonary epithelium
PRAXIS XXI/BM/19331/99
Bolseiro de Mestrado
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Concluído

Projeto

Designação Financiadores
2019/01/04 - 2025/01/03 Not Available
DL 57/2016/CP1448/CT0012
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2021 - 2021 Bipolar Disease: Another Side. Science communication project
#385-PCC2021
Universidade de Coimbra
Em curso
2018 - 2021 Role of anthocyanins from Portuguese blueberries on gut-to-brain connection in autism spectrum disorder by using in vitro and in vivo models
POCI-01-0145-FEDER-029089
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018 - 2021 Skin allergens: molecules with an improbable therapeutic application for Alzheimer’s disease
CENTRO-01-0145-FEDER-029369
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2018 - 2021 The ups and downs of cellular stress: the “MAM hypothesis” for Bipolar disorder pathophysiology
CENTRO-01-0145-FEDER-028214
Investigador
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
Em curso
2018 - 2021 InPaCTus sub-project Extracts of high added value from forest biomass¿.
COMPETE2020 nº 21874
Investigador
N/A
2013/06 - 2015/06 Tackling Alzheimer's Disease with a new peptide inhibitor of BACE1 Fundação para a Ciência e a Tecnologia, I.P.
2012 - 2015 Development of a new drug for the treatment of Alzheimer's disease
INOV.C
N/A
2012/05 - 2014/10 The impact of exendin-4 therapy in the molecular mechanisms underlying type 2 diabetes-related long-term brain dysfunction Fundação para a Ciência e a Tecnologia, I.P.
2011/03 - 2013/08 Mitochondrial preconditioning: potential neuroprotective effect in Alzheimer's disease Fundação para a Ciência e a Tecnologia, I.P.
2010/01 - 2013/06 Radiolabeled Benzazole Derivatives for In Vivo Imaging of Amyloid Aggregation Fundação para a Ciência e a Tecnologia, I.P.
Concluído
Produções

Publicações

Artigo em conferência
  1. Resende, Rosa; Baptista, Márcio; Pereira, Cláudia Fragão; Oliveira, Catarina R. "In vitro study of Amyloid-ß peptide toxicity. The role of physical state.". Trabalho apresentado em 10th International Conference on Alzheimer’s Disease and Related Disorders, Madrid, 2006.
    Publicado
Artigo em jornal
  1. Resende, Rosa; Silva, Ana; Cláudia Maria Fragão Pereira (PhD); Moreira, Paula Isabel; Santos, Armanda E; Cruz, Maria Teresa; Fernandes, Tânia; et al. "Doenças neurodegenerativas: um quebra-cabeças com solução à vista", O Público, 2021
  2. Resende, Rosa. ""Uma Viagem Bipolar". Comic about Bipolar Disorder created in the scope of the #BrainWeek celebrations and published on "Público". https://www.publico.pt/2021/03/30/ciencia/noticia/viagem-bipolar-1956372?fbclid=IwAR1yxixpbowS1JXz5owYAKmAzUwTVumfHZ24X_JvwYClWV8w5BQ2lc_t1hE", O Público, 2021
Artigo em revista
  1. Fernandes, Tânia; Melo, Tânia; Conde, Tiago; Neves, Bruna; Domingues, Pedro; Resende, Rosa; Pereira, Cláudia F.; Moreira, Paula I.; Domingues, Maria Rosário. "Mapping the lipidome in mitochondria-associated membranes (MAMs) in an in vitro model of Alzheimer's disease". Journal of Neurochemistry (2024): http://dx.doi.org/10.1111/jnc.16072.
    Publicado • 10.1111/jnc.16072
  2. Diana Serra; Joana Henriques; Fábio J. Sousa; Mariana Laranjo; Resende R; Ferreira-Marques, M.; Victor de Freitas; et al. "Attenuation of Autism-like Behaviors by an Anthocyanin-Rich Extract from Portuguese Blueberries via Microbiota–Gut–Brain Axis Modulation in a Valproic Acid Mouse Model". International Journal of Molecular Sciences (2022): https://www.mdpi.com/1422-0067/23/16/9259.
    10.3390/ijms23169259
  3. Pereira, Ana Catarina; De Pascale, Jessica; Resende, Rosa; Cardoso, Susana; Ferreira, Isabel; Neves, Bruno Miguel; Carrascal, Mylene A.; et al. "ER-mitochondria communication is involved in NLRP3 inflammasome activation under stress conditions in the innate immune system". Cellular and Molecular Life Sciences (2022): https://publons.com/wos-op/publon/51936837/.
    10.1007/S00018-022-04211-7
  4. Resende, Rosa; Fernandes, Tania; Pereira, Ana Catarina; Marques, Ana Patricia; Pereira, Claudia Fragao. "Endoplasmic Reticulum-Mitochondria Contacts Modulate Reactive Oxygen Species-Mediated Signaling and Oxidative Stress in Brain Disorders: The Key Role of Sigma-1 Receptor". Antioxidants & Redox Signaling (2022): https://publons.com/wos-op/publon/54098042/.
    10.1089/ARS.2020.8231
  5. Fernandes, Tânia; Resende R; Diana F. Silva; Ana P. Marques; AE Santos; Sandra M. Cardoso; Maria Rosario Domingues; Moreira PI; C Pereira. "Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer’s Disease". Biomedicines (2021): https://www.mdpi.com/2227-9059/9/8/881.
    10.3390/biomedicines9080881
  6. Marques, A.P.; Resende, R.; Silva, D.F.; Batista, M.; Pereira, D.; Wildenberg, B.; Morais, S.; et al. "Mitochondrial alterations in fibroblasts of early stage bipolar disorder patients". Biomedicines 9 5 (2021): http://www.scopus.com/inward/record.url?eid=2-s2.0-85106639786&partnerID=MN8TOARS.
    10.3390/biomedicines9050522
  7. Resende, Rosa. "Calcium Modulation, Anti-Oxidant and Anti-Inflammatory Effect of Skin Allergens Targeting the Nrf2 Signaling Pathway in Alzheimer's Disease Cellular Models.". International journal of molecular sciences (2020): https://europepmc.org/articles/PMC7594024.
    10.3390/ijms21207791
  8. Resende, Rosa. "New BACE1 Chimeric Peptide Inhibitors Selectively Prevent AßPP-ß Cleavage Decreasing Amyloid-ß Production and Accumulation in Alzheimer’s Disease Models". Journal of Alzheimer's Disease (2020): https://doi.org/10.3233/JAD-200381.
    10.3233/JAD-200381
  9. Resende, R.; Fernandes, T.; Pereira, A.C.; De Pascale, J.; Marques, A.P.; Oliveira, P.; Morais, S.; et al. "Mitochondria, endoplasmic reticulum and innate immune dysfunction in mood disorders: Do mitochondria-associated membranes (MAMs) play a role?". Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2020): 165752. http://dx.doi.org/10.1016/j.bbadis.2020.165752.
    10.1016/j.bbadis.2020.165752
  10. Resende, Rosa. "The role of proteotoxic stress in vascular dysfunction in the pathogenesis of Alzheimer's disease". (2015):
    0.1515/ersc-2015-0005
  11. Valente, J.; Resende, R.; Zuzarte, M.; Gonçalves, M.J.; Lopes, M.C.; Cavaleiro, C.; Pereira, C.; Salgueiro, L.; Cruz, M.T.. "Bioactivity and safety profile of Daucus carota subsp. maximus essential oil". Industrial Crops and Products 77 (2015): 218-224. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941194381&partnerID=MN8TOARS.
    10.1016/j.indcrop.2015.08.037
  12. Resende, Rosa. "Daucus carota subsp. gummifer essential oil as a natural source of antifungal and anti-inflammatory drugs.". Industrial Crops and Products (2015):
    10.1016/j.indcrop.2014.11.014
  13. Videira, R.; Castanheira, P.; Grãos, M.; Resende, R.; Salgueiro, L.; Faro, C.; Cavaleiro, C.. "Dose-dependent inhibition of BACE-1 by the monoterpenoid 2,3,4,4-tetramethyl-5-methylenecyclopent-2-enone in cellular and mouse models of Alzheimer's disease". Journal of Natural Products 77 6 (2014): 1275-1279. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903648214&partnerID=MN8TOARS.
    10.1021/np400903w
  14. Gomes, S.; Martins, I.; Fonseca, A.C.R.G.; Oliveira, C.R.; Resende, R.; Pereira, C.M.F.. "Protective effect of leptin and ghrelin against toxicity induced by amyloid-ß oligomers in a hypothalamic cell Line". Journal of Neuroendocrinology 26 3 (2014): 176-185. http://www.scopus.com/inward/record.url?eid=2-s2.0-84897877226&partnerID=MN8TOARS.
    10.1111/jne.12138
  15. Correia, S.C.; Resende, R.; Moreira, P.I.; Pereira, C.M.. "Alzheimer's disease-related misfolded proteins and dysfunctional organelles on autophagy menu". DNA and Cell Biology 34 4 (2014): 261-273. http://www.scopus.com/inward/record.url?eid=2-s2.0-84926636149&partnerID=MN8TOARS.
    10.1089/dna.2014.2757
  16. Resende, R.; Marques, S.C.F.; Ferreiro, E.; Simões, I.; Oliveira, C.R.; Pereira, C.M.F.. "Effect of a-Synuclein on amyloid ß-Induced toxicity: Relevance to lewy body variant of alzheimer disease". Neurochemical Research 38 4 (2013): 797-806. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876164250&partnerID=MN8TOARS.
    10.1007/s11064-013-0982-7
  17. Martins, I.; Gomes, S.; Costa, R.O.; Otvos, L.; Oliveira, C.R.; Resende, R.; Pereira, C.M.F.. "Leptin and ghrelin prevent hippocampal dysfunction induced by Aß oligomers". Neuroscience 241 (2013): 41-51. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876430099&partnerID=MN8TOARS.
    10.1016/j.neuroscience.2013.02.062
  18. Costa, R.O.; Lacor, P.N.; Ferreira, I.L.; Resende, R.; Auberson, Y.P.; Klein, W.L.; Oliveira, C.R.; Rego, A.C.; Pereira, C.M.F.. "Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-ß oligomers". Aging Cell 11 5 (2012): 823-833. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866452758&partnerID=MN8TOARS.
    10.1111/j.1474-9726.2012.00848.x
  19. Resende, R.; Oliveira, C.R.; Pereira, C.M.F.. "Role of glycogen synthase kinase-3ß on tau phosphorylation in Alzheimer's disease". Alzheimer's Disease Research Journal 3 3-4 (2011): 193-206. http://www.scopus.com/inward/record.url?eid=2-s2.0-82755187718&partnerID=MN8TOARS.
  20. Fonseca, A.C.R.G.; Resende, R.; Oliveira, C.R.; Pereira, C.M.F.. "Cholesterol and statins in Alzheimer's disease: Current controversies". Experimental Neurology 223 2 (2010): 282-293. http://www.scopus.com/inward/record.url?eid=2-s2.0-77952583554&partnerID=MN8TOARS.
    10.1016/j.expneurol.2009.09.013
  21. Ferreira, I.L.; Resende, R.; Ferreiro, E.; Rego, A.C.; Pereira, C.F.. "Multiple defects in energy metabolism in Alzheimer's disease". Current Drug Targets 11 10 (2010): 1193-1206. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957994659&partnerID=MN8TOARS.
  22. Resende, Rosa; Oliveira, Catarina Resende; Pereira, Claudia M. F.. "ROLE OF GLYCOGEN SYNTHASE KINASE-3B ON TAU PHOSPHORYLATION IN ALZHEIMER'S DISEASE". Advances in Medicine and Biology, Vol 2 2 (2010): 197-210. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000278696200007&KeyUID=WOS:000278696200007.
  23. Fonseca, A.C.R.G.; Proena, T.; Resende, R.; Oliveira, C.R.; Pereira, C.M.F.. "Neuroprotective effects of statins in an in vitro model of alzheimer's disease". Journal of Alzheimer's Disease 17 3 (2009): 503-517. http://www.scopus.com/inward/record.url?eid=2-s2.0-67849099662&partnerID=MN8TOARS.
    10.3233/JAD-2009-1067
  24. Resende, R.; Ferreiro, E.; Pereira, C.; Resende de Oliveira, C.. "Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: Involvement of endoplasmic reticulum calcium release in oligomer-induced cell death". Neuroscience 155 3 (2008): 725-737. http://www.scopus.com/inward/record.url?eid=2-s2.0-49249118742&partnerID=MN8TOARS.
    10.1016/j.neuroscience.2008.06.036
  25. Resende, R.; Moreira, P.I.; Proença, T.; Deshpande, A.; Busciglio, J.; Pereira, C.; Oliveira, C.R.. "Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease". Free Radical Biology and Medicine 44 12 (2008): 2051-2057. http://www.scopus.com/inward/record.url?eid=2-s2.0-43849096294&partnerID=MN8TOARS.
    10.1016/j.freeradbiomed.2008.03.012
  26. Resende, R.; Ferreiro, E.; Pereira, C.; Oliveira, C.R.. "ER stress is involved in Aß-induced GSK-3ß activation and tau phosphorylation". Journal of Neuroscience Research 86 9 (2008): 2091-2099. http://www.scopus.com/inward/record.url?eid=2-s2.0-48249157930&partnerID=MN8TOARS.
    10.1002/jnr.21648
  27. Resende, R.; Pereira, C.; Agostinho, P.; Vieira, A.P.; Malva, J.O.; Oliveira, C.R.. "Susceptibility of hippocampal neurons to Aß peptide toxicity is associated with perturbation of Ca2+ homeostasis". Brain Research 1143 1 (2007): 11-21. http://www.scopus.com/inward/record.url?eid=2-s2.0-33947303240&partnerID=MN8TOARS.
    10.1016/j.brainres.2007.01.071
  28. Ferreiro, E.; Resende, R.; Costa, R.; Oliveira, C.R.; Pereira, C.M.F.. "An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity". Neurobiology of Disease 23 3 (2006): 669-678. http://www.scopus.com/inward/record.url?eid=2-s2.0-33747195017&partnerID=MN8TOARS.
    10.1016/j.nbd.2006.05.011
  29. Egas, C.; Lavoura, N.; Resende, R.; Brito, R.M.M.; Pires, E.; Pedroso De Lima, M.C.; Faro, C.. "The saposin-like domain of the plant aspartic proteinase precursor is a potent inducer of vesicle leakage". Journal of Biological Chemistry 275 49 (2000): 38190-38196. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034623993&partnerID=MN8TOARS.
    10.1074/jbc.M006093200
Capítulo de livro
  1. Resende, R.; Oliveira, C.R.; Pereira, C.M.F.. "Role of glycogen synthase kinase-3B on tau phosphorylation in alzheimer’s disease". 197-210. 2010.
Edição de livro
  1. .. Women in aging neuroscience 2021.. Lausanne: Frontiers Media SA. 2023.
    Publicado • Editor
Poster em conferência
  1. Serra, Diana; Joana Henriques; Sousa, Fábio J.; Laranjo, Mariana; Resende, Rosa; Ferreira-Marques, Marisa; Freitas, Victor; et al. "AN ANTHOCYANIN-RICH EXTRACT FROM PORTUGUESE BLUEBERRIES AS A NOVEL STRATEGY FOR THE MANAGEMENT OF AUTISM SPECTRUM DISORDERS: AN IN VIVO MODEL". Trabalho apresentado em 4th International Conference on Food Bioactives and Health, 2023.
  2. Beatriz Rodrigues; Eduarda Ventura; Moreira, Patricia; Armanda E. Santos; Resende, Rosa; Claudia Pereira; Cruz, Maria T.; et al. "NEW LOW-DOSE CURCUMIN DERIVATIVES PREVENT NEUROINFLAMMATION IN ALZHEIMER¿S DISEASE". Trabalho apresentado em 37º Reunião Anual do Grupo de Estudos do Envelhecimento Cerebral e Demência (GECD), 2023.
  3. Silva, Ana Cristina Rosa da; Pereira, Marta; Carrascal, Mylene; Brites, Gonçalo Sousa; Neves, Bruno; Moreira, Patricia; Resende, Rosa; et al. "EFFECT OF SKIN ALLERGENS TARGETING NRF2 TRANSCRIPTION FACTOR ACTIVATION ON ALZHEIMER¿S DISEASE HALMARKS". Trabalho apresentado em 15th International Conference on Alzheimer's and Parkinson's Diseases (ADPD2021), 2021.
  4. Silva, Ana; Pereira, Marta; Brites, Gonçalo; Neves, Bruno; Moreira, Patricia; Resende, Rosa; Silva, Maria Manuel; et al. "Skin allergens and Alzheimer´s disease: preliminary studies on an (im)probable link". Trabalho apresentado em Cell Signalingin Aging and Neurodegenerative Diseases, Coimbra, Portugal, 2019.
  5. Resende, Rosa; Moreira, Patricia; Ferreira-Marques, Marisa; Dinis, Teresa; Oliveira, Francisco; Sereno, José; Abrunhosa, Antero; et al. "New chimeric peptides selectively inhibit APPß cleavage decreasing Aß formation and accumulation in AD models". Trabalho apresentado em 14th International Conference on Alzheimer's & Parkinson's Diseases, Lisbon, Portugal, 2019.
  6. Silva, Ana Cristina Rosa da; Pereira, Marta; Brites, Gonçalo Sousa; Neves, Bruno; Moreira, Patricia; Resende, Rosa; Silva, MMC; et al. "Skin allergens and Alzheimer´s disease: preliminar studies on na (im)probable link". Trabalho apresentado em . 8th ECS workshop Calcium Signalin in Aging and Neurodegenerative Diseases, 2019.
  7. Resende, Rosa; Ferreira-Marques, Marisa; Dinis, Teresa; Oliveira, F; Sereno, J; Abrunhosa, Antero; Castelo-Branco, Miguel; Pereira, Cláudia; Santos, Armanda E. "New BACE1 inhibitors decrease Aß production and accumulation in the 3xTg-AD mouse model". Trabalho apresentado em 13th International Conference on Alzheimer¿s & Parkinson Diseases, 2017.
  8. Ferreira-Marques, Marisa; Resende, Rosa; Pereira, Cláudia; Dinis, Teresa; Santos, Armanda E. "New BACE1 inhibitors for Alzheimer´s disease treatment.". Trabalho apresentado em 19th European Synposium on Organyc Chemistry (ESOC 2015), 2015.
  9. Ferreira-Marques, Marisa; Resende, Rosa; Pereira, Cláudia; Dinis, Teresa; Santos, Armanda E. "Tackling Alzheimer´s disease with a new inhibitor of BACE1: evaluation of peptide efficiency in vitro and in an in vivo model of AD". Trabalho apresentado em XIV Meeting of the Portuguese Society for Neurosciences, 2015.
  10. Ferreira-Marques, Marisa; Resende, Rosa; Pereira, Cláudia; Dinis, Teresa; Santos, Armanda. "Tackling Alzheimer's disease with a new inhibitor of BACE1: evaluation of compound efficacy in vitro and in a cellular model of Alzheimer's disease". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, Coimbra, Portugal, 2014.
  11. Ferreira-Marques, Marisa; Resende, Rosa; Pereira, Cláudia; Dinis, Teresa; Santos, Armanda E. "Tackling Alzheimer´s disease with a new inhibitor of BACE1: evaluation of compound efficacy in vitro and in a celular model of AD". Trabalho apresentado em XVIII Congress of the Portuguese Biochemical Society, 2014.
Resumo em conferência
  1. Pereira, A. C.; Marques, A. P.; Resende, R.; Batista, M.; Macedo, A.; Claudia Pais, C.; Melo, J. B.; Madeira, N.; Pereira, C.. "Mitochondria-associated membranes (MAMs) and sterile inflammation in bipolar disorder". Trabalho apresentado em 56th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)., Bari, 2022.
  2. Fernandes, T.; Resende, R.; Domingues, M. R.; Moreira, P.; Pereira, C.. "Physical and biochemical alterations in endoplasmic reticulum-mitochondria contacts in an Alzheimer's disease in vitro model". Trabalho apresentado em 55th Annual Scientific Meeting of the European Society for Clinical Investigation, 2021.
    Publicado
  3. Resende, Rosa; Ferreira-Marques, Marisa; Dinis, Teresa; Pereira, Cláudia Fragão; Santos, Armanda E. "New BACE1 inhibitors decrease Aß production in cellular and in vivo models of Alzheimer’s disease.". Trabalho apresentado em 30th Meeting of the Portuguese Group of Studies on Aging and Dementia, Lisboa, 2016.
    Publicado
  4. Ferreira-Marques, Marisa; Resende, Rosa; Pereira, Cláudia Fragão; Dinis, Teresa. "New promising peptides to inhibit BACE1: evaluation of compound efficiency in cellular and mouse models of Alzheimer’s disease.". Trabalho apresentado em 29th Meeting of the Portuguese Group of Studies on Aging and Dementia., Aveiro, 2015.
    Publicado
  5. Valente, Júlia; Resende, Rosa; Zuzarte, Mónica; Gonçalves, MJ; Lopes, MC; Cavaleiro, Carlos; Pereira, Cláudia Fragão; Salgueiro, Lígia; Cruz, Maria Teresa. "Antifungal and anti-inflammatory claims for wild carrot essential oil.". Trabalho apresentado em 62nd International Congress and Annual Meeting of the Society of Medicinal Plant and Natural Product Research, Guimarães, 2014.
    Publicado • 10.1055/s-0034-1394792
  6. Ferreiro, Elisabete; Costa, Rui O; Resende, Rosa; Pereira, Cláudia Fragão. "Communication between endoplamic reticulum and mitochondria in the neuronal death induced by amyloid-beta peptide.". Trabalho apresentado em 5th International Congress on Vascular Dementia, Budapest, 2009.
    Publicado • 10.1016/j.jns.2009.02.158
  7. Pereira, Cláudia Fragão; Fonseca, Ana Catarina; Resende, Rosa; Resende, Catarina R. "Statins prevent beta-amyloid-induced toxicity in cortical neurons.". Trabalho apresentado em 5th International Congress on Vascular Dementia, Budapest, 2009.
    Publicado • 10.1016/j.jns.2009.02.159
  8. Resende, Rosa; Moreira, Paula Isabel; Deshpande, Atul; Busciglio, Jorge; Pereira, Cláudia Fragão; Oliveira, Catarina R. "Increased oxidative stress is an early pathological feature in 3xTg-AD mice.". Trabalho apresentado em Alzheimer's Association International Conference on Alzheimer's Disease (ICAD), Chicago, 2008.
    Publicado • 10.1016/j.jalz.2008.05.2250
  9. Pereira, Cláudia Fragão; Costa, Rui O; Resende, Rosa; Cardoso, Sandra; Oliveira, Catarina R. "Cross-talk between endoplasmic reticulum and mitochondria in the neurotoxicity induced by Alzheimer's disease–associated beta-amyloid peptide.". Trabalho apresentado em Alzheimer's Association International Conference on Alzheimer's Disease, Chicago, 2008.
    Publicado • 10.1016/j.jalz.2008.05.1011
  10. Ferreiro, Elisabete; Resende, Rosa; Costa, Rui O; Pereira, Cláudia Fragão. "Neurodegeneration in Alzheimer's disease: Inter-organelle cross-talk and oxidative stress in cell life and death decisions.". Trabalho apresentado em European Meeting of the Society-for-Free-Radical-Research-Europe (SFRR-Europe), Vilamoura, 2007.
    Publicado • 10.1080/10715760701615118
  11. Resende, Rosa; Baptista, Márcio; Pereira, Cláudia Fragão; Oliveira, Catarina R. "In vitro study of amyloid-ß peptide toxicity. The role of physical state.". Trabalho apresentado em Alzheimer's Association 10th International Conference on Alzheimer's Disease and Related Disorders., Madrid, 2006.
    Publicado • 10.1016/j.jalz.2006.05.1834
  12. Ferreiro, Elisabete; Resende, Rosa; Oliveira, Catarina R; Pereira, Cláudia Fragão. "Mechanism of amyloid-beta induced early synaptotoxicity". Trabalho apresentado em Reunião da Sociedade Portuguesa de Neurociências, Luso, 2005.
    Publicado

Propriedade Intelectual

Patente
  1. 6A1D-22C8-B2A3; 6111-F90A-3CE1; 001F-06FD-384B; Resende, Rosa. 2022. "Small molecules for use in preventing and/or treatment of neurodegenerative diseases.".
    Pendente
  2. Resende, Rosa; Santos, Armanda E; Dinis, Teresa; Pereira, Cláudia Fragão. 2021. ""Peptide inhibitors of BACE1 for the treatment of neurological disorders"". Portugal.
    Concedida/Emitida
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2023/12/02 The endoplasmic reticulum (ER)-mitochondria communication in schizophrenia. Mitochondria in Aging, Cancer and Cell Death (MAC 2023), Rosa30th November-02nd December
Univiersidade de Coimbra (Coimbra, Portugal)
2023/06/10 Mitochondria-associated membranes (MAMs) and sterile inflammation in Bipolar disorder. 56th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI).
(Bari)
2023/06/09 Dysfunction of endoplasmic reticulum-mitochondria contacts in bipolar disorder. 57th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
(Prague, República Checa)
2023/05/31 ER-mitochondria contacts in schizophrenia. DCV.talks
Faculty of Sciences, University of Coimbra (Coimbra, Portugal)
2023/05/12 Alterations in the contacts between endoplasmic reticulum and mitochondria in Bipolar disorder. MitoPorto 2023
University of Porto (Porto, Portugal)
2023/02/03 Alterations in the ER-mitochondria contacts affect lipid metabolism in an Alzheimer’s disease in vitro model. 53ª Reunião da Sociedade Portuguesa de Farmacologia.
Faculty of Pharmacy, University of Coimbra (Coimbra, Portugal)
2023/02/03 Impairment of mitochondria-associated membranes (MAMs) in Bipolar disorder. 53ª Reunião da Sociedade Portuguesa de Farmacologia. Coimbra, Portugal. 1st-3rd February, 2023.
Faculty of Pharmacy, University of Coimbra (Coimbra, Portugal)
2022/11/10 Relevância dos contactos intracelulares na esquizofrenia Research Methods and Techniques course, Master in Biomedical Research, Faculty of Medicine, University of Coimbra, Coimbra, Portugal.
2022/02/10 Skin allergens: molecules with possible application in disease. 52ª Reunião da Sociedade Portuguesa de Farmacologia
Instituto de Ciências Biomédicas de Abel Salazar da Universidade do Porto (Porto, Portugal)
2022/02/09 Endoplasmic Reticulum (ER)-Mitochondria contacts and inflammation in bipolar disorder. 52ª Reunião da Sociedade Portuguesa de Farmacologia
Instituto de Ciências Biomédicas de Abel Salazar da Universidade do Porto (Porto, Portugal)
2021/06/09 Physical and biochemical alterations in endoplasmic reticulum-mitochondria contacts in an Alzheimer's disease in vitro model. 55th Annual Scientific Meeting of the European Society for Clinical Investigation (ESCI)
2021/03 Mitochondrial (dys)function and dynamics in fibroblasts of early bipolar disorder patients 20th WPA World Congress of Psychiatry
World Psychiatry Association
2020/11/18 New BACE1 chimeric peptide inhibitors selectively prevent AßPP-ß cleavage decreasing Aß production and accumulation in AD models. 1st Scientific Retreat of Metabolism, Aging and Disease Area. Online Meeting.
(Portugal)
2020/02/07 Changes in the protein composition of mitochondrial-associated membranes (MAMs) in Alzheimer’s disease. L Reunião da Sociedade Portuguesa de Farmacologia, XXXVIII Reunião de Farmacologia Clínica e XIX Reunião de Toxicologia. Coimbra
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2020/02/06 Electrophilic molecules with anti-inflammatory and neuroprotective properties. L Reunião da Sociedade Portuguesa de Farmacologia, XXXVIII Reunião de Farmacologia Clínica e XIX Reunião de Toxicologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2018/10/12 New chimeric peptides selectively inhibit APP-ß cleavage. 32rd Meeting of the Portuguese Group of Studies on Aging and Dementia
GEECD (Lisboa, Portugal)
2017/11/08 New strategies to target BACE1: towards Alzheimer's disease treatment. Research Methods and Techniques course, Master in Biomedical Research
Faculdade de Medicina, Universidade de Coimbra
2017/05/19 New peptide inhibitors of BACE1: Towards Alzheimer’s treatment. Seminar of Neurobiologia II course unit, Integrated Master in Biomedical Engineering
Faculdade de Ciências e Tecnologia, Universidade de Coimbra
2017/05/06 Doenças neurodegenerativas e mitocôndria. Morte celular e autofagia. Biomedicina: Mitocôndria e doenças advanced course
Instituto de Educação e Cidadania (IEC) (Oliveira do Bairro, Portugal)
2017/02/04 New peptide inhibitors of BACE1: Towards Alzheimers treatment. XLVII Reunião anual da Sociedade Portuguesa de farmacologia.
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)
2016/11/10 Peptide inhibitors of BACE1 for the treatment of neurological disorders. Research Methods and Techniques course, Master in Biomedical Research
Faculdade de Medicina, Universidade de Coimbra
2016/06/03 New BACE1 inhibitors decrease Aß production in cellular and in vivo models of Alzheimer’s disease. 30th Meeting of the Portuguese Group of Studies on Aging and Dementia.
Portuguese Group of Studies on Aging and Dementia. (Lisboa, Portugal)
2016/02 New BACE1 inhibitors for Alzheimer´s Disease treatment: evaluation of their eficacy in in vitro and in vivo models. XV EPI: 15th Iberian Peptide Meeting.
2015/11/05 Peptide inhibitors of BACE1 for the treatment of neurological disorders. Research Methods and Techniques course, Master in Biomedical Research
Faculdade de Medicina, Universidade de Coimbra
2015/05 New promising peptides to inhibit BACE1: evaluation of compound efficiency in cellular and mouse models of Alzheimer’s disease. 29th Meeting of the Portuguese Group of Studies on Aging and Dementia
Portuguese Group of Studies on Aging and Dementia (Aveiro, Portugal)
2013/10/29 Cellular and animal models in neuroscience. Research Methods and Techniques course, Master in Biomedical Research
Faculdade de Medicina, Universidade de Coimbra
2013/02/25 Endoplasmic reticulum stress in Alzheimer's disease. Doctoral Programme in Health Sciences
Faculdade de Medicina, Universidade de Coimbra
2011/06/03 Leptin and ghrelin prevent hippocampal dysfunction induced by Aß oligomers. 25th Meeting of the Portuguese Group of Studies on Aging and Dementia
GEECD (Tomar, Portugal)
2010/06/25 Leptin and Ghrelin protect against Aß-induced toxicity in hypothalamic cells. 24th Meeting of the Portuguese Group of Studies on Aging and Dementia.
GEECD (Tomar, Portugal)
2010/06/25 Neuroprotection by leptin and ghrelin against amyloid-beta toxicity in hippocampal neurons. Relevance for therapeutic intervention in Alzheimer’s disease. 24th Meeting of the Portuguese Group of Studies on Aging and Dementia.
GEECD (Tomar, Portugal)
2009/06 On the way to therapeutic targets. 23rd Meeting of the Portuguese Group of Studies on Aging and Dementia.
Portuguese Group of Studies on Aging and Dementia. (Luso, Portugal)
2009/02/16 Stress oxidativo num modelo animal da doença de Alzheimer. Project GAPI - Mostra Científica.
Faculdade de Medicina, Universidade de Coimbra (Coimbra, Portugal)
2007/06/08 Aß1-42 oligomers induce endoplasmic reticulum stress and GSK3ß-mediated Tau phosphorylation. 21rd Meeting of the Portuguese Group of Studies on Aging and Dementia. Luso, Portugal.
GEECD (Luso, Portugal)
2007/06/08 Efeito neuroprotector de estatinas num modelo in vitro da Doença de Alzheimer. 21rd Meeting of the Portuguese Group of Studies on Aging and Dementia
GEECD (Luso, Portugal)
2006/12/05 Endoplasmic reticulum-specific apoptotic pathway induced by prion and amyloid-beta peptides. XXXIV Reunião anual da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Porto, Portugal)
2006/12 Neuronal susceptibility to different assemblies of Aß peptide. IV Encontro Anual do CNC
Centro de Neurociências de Coimbra (Luso, Portugal)
2006/06/23 Amyloid-beta peptide and tau pathology. Role of glycogen synthase kinase-3ß. 20th Meeting of the Portuguese Group of Studies on Aging and Dementia.
GEECD (Tomar, Portugal)
2005/05/19 Mechanism of amyloid-beta induced early synaptotoxicity. 9th Meeting of the Portuguese Society for Neuroscience
Sociedade Portuguesa de Neurociências (Luso, Portugal)
2004/12/02 Role of beta-amyloid peptides on Alzheimer´s disease neuronal degeneration. XIV Congresso Nacional de Bioquímica
Sociedade Portuguesa de Bioquímica (Vilamoura, Portugal)
2004/11/17 Susceptibilidade dos neurónios de hipocampo e córtex à toxicidade do peptídeo beta-amilóide associado à doença de Alzheimer. IV Congresso de Investigação em Medicina
Universidade de Coimbra (Coimbra, Portugal)
2004/11/17 A influência da internalização e do estado de agregação na neurotoxicidade dos peptídeos beta-amilóide. IV Congresso de Investigação em Medicina
Universidade de Coimbra (Coimbra, Portugal)
2004/11 Susceptibilidade dos neurónios de hipocampo e córtex à toxicidade do peptídeo beta-amilóide associado à doença de Alzheimer. IV Congresso de Investigação em Medicina
(Coimbra, Portugal)
2004 Role of beta-amyloid peptides on Alzheimer´s disease neuronal degeneration XIV Congresso Nacional de Bioquímica.
Sociedade Portuguesa de Bioquìmica (Vilamoura, Portugal)
2003/12/04 Differential susceptibility of cortical and hippocampal neurons to amyloid-beta peptides toxicity. XXXIV Reunião anual da Sociedade Portuguesa de Farmacologia
Sociedade Portuguesa de Farmacologia (Coimbra, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2020/11 - 2021/12/06 Perturbation of endoplasmic reticulum-mitochondria crosstalk in Bipolar disorder: effect of Sigma-1 receptor modulation.
Orientador
Biologia Celular e Molecular (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2016 - 2017 Doença de Alzheimer: estudo dos efeitos biológicos de um novo inibidor da BACE1
Coorientador
Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2016 Biological effects of new BACE1 inhibitors for Alzheimer’s disease treatment
Coorientador
Integrated Master in Biomedical Engineering (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2015 - 2016 Role of oxygen species in inflammasome activation in microglia under stress conditions
Coorientador
Integrated Master in Medicine (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2013 - 2014 How does autophagy modulate inflammasome activation in aging? Is the ER stress involved?
Orientador
Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013 - 2014 How does autophagy modulate inflammasome activation in aging? Is the ER stress involved?
Orientador
Biochemistry (Licenciatura/Bacharelato)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2013 - 2014 How does autophagy modulate inflammasome activation in aging? Is the ER stress involved?
Orientador
Biochemistry (Licenciatura/Bacharelato)

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2020/11/06 - 2020/11/06 Seminar "Mental disorders – searching for the (un)known" presented by Bruno Manadas, Center for Neuroscience and Cell Biology (CNC), University of Coimbra (2020/11/06 - 2020/11/06)
Seminário (Coorganizador)
Universidade de Coimbra Centro para a Inovação em Biomedicina e Biotecnologia (CIBB), Portugal
2011 - 2011 Neuroendocrinology and Neuromodulation Advanced Course. Experimental Biology and Biomedicine PhD Programme, Center for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal. http://beb.cnbc.pt/det_courses.asp?id=531 (2011) (2011/12/05 - 2011/12/09)
Outro (Coorganizador)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009 - 2009 Brain Awareness Week. Participation and organization of Science exhibitions and visits to schools (1st to 12th grades). (2009/03/16 - 2009/03/22) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Participação em evento

Descrição da atividade
Tipo de evento
Nome do evento
Instituição / Organização
2004 - 2023 Brain Awareness Week. Participation and organization of Science exhibitions and visits to schools (1st to 12th grades).
Outro
Brain Awareness Week
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2021/12/01 - 2021/12/03 Poster presentation: Ana Catarina Pereira, Ana Patrícia Marques, Rosa Resende, Mariana Batista, António Macedo, Cláudia Pais, Joana B. Melo, Nuno Madeira, Cláudia Pereira. Endoplasmic Reticulum (ER)-mitochondria coupling and inflammation in Bipolar disorder (BD) patients-derived fibroblasts. XVII Meeting of the Portuguese Society for Neuroscience. Coimbra, Portugal.
Conferência
XVII Meeting of the Portuguese Society for Neuroscience.
2020/11/01 - 2020/11/30 ASK (Always Seeking Knowledge) Researchers. Yin and Yang in Bipolar Disease: Failure in Cell Communication?" https://www.youtube.com/watch?v=DzRPqluso6c
Outro
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2020/07/11 - 2020/07/15 Poster presentation: Rosa Maria Resende, Patrícia Marques, Tânia Fernandes, Diana Silva, Mariana Batista, Sofia Morais, António Macedo, Cláudia Pais, Joana B. Melo, Nuno Madeira, Cláudia Pereira. Endoplasmic Reticulum (ER)-mitochondria contact in bipolar disorder fibroblastos. FENS 2020 Virtual Forum.
Conferência
FENS 2020 Virtual Forum
2020/01/30 - 2020/02/01 Poster presentation: Rosa Resende; Patrícia Marques; Tânia Fernandes; Mariana Batista; Sofia Morais; Vítor Santos; António Macedo; Cláudia Pais; Joana B. Melo; Nuno Madeira; Cláudia Pereira. Endoplasmic Reticulum (ER) and mitochondrial alterations in Bipolar disorder fibroblastos. XIV Congresso Nacional de Psiquiatria 2020. Tróia, Portugal.
2019/09/18 - 2019/09/20 8th ECS workshop. Calcium Signalling in Aging and Neurodegenerative Diseases. Hands-on on microscopy calcium imaging at Microscopy Imaging Center of Coimbra.
Oficina (workshop)
European Society of Calcium, Bélgica
2019/09/18 - 2019/09/20 Poster presentation: Ana Silva, Marta Pereira, Bruno Neves, Patrícia Moreira, Rosa Resende, Maria Manuel Silva, Armanda Santos, Cláudia Pereiraa, Maria Teresa Cruz. Skin allergens and Alzheimer´s disease: preliminary studies on an (im)probable link. Coimbra, Portugal. 8th ECS workshop. Calcium Signalling in Aging and Neurodegenerative Diseases.
2019/03/26 - 2019/03/31 Poster presentation: Rosa Resende, Patrícia Moreira, Marisa Ferreira-Marques, Teresa Dinis, Francisco Oliveira, José Sereno, Antero Abrunhosa, Miguel Castelo Branco, Cláudia Pereira, Armanda E. Santos. New chimeric peptides selectively inhibit APPß cleavage decreasing Aß formation and accumulation in AD models. 14th International Conference on Alzheimers and Parkinsons Diseases (ADPD 2019). Lisbon, Portugal.
2019 - 2019 National Scientific Programme Ciência Viva - ocupação científica dos jovens nas férias. Summer laboratory activities with High School students. Ciência Viva – ocupação científica dos jovens nas férias
2019 - 2019 Science and Technology Portuguese Week. Participation and organization of laboratory activities with High School students.
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2017/04/05 - 2017/04/05 6th Workshop in Lipidomics
Oficina (workshop)
Universidade de Aveiro, Portugal
2017/03/29 - 2017/04/02 Poster presentation: Rosa Resende, Marisa Ferreira-Marques, Teresa Dinis, Francisco Oliveira, José Sereno, Antero Abrunhosa, Miguel Castelo Branco, Cláudia Pereira, Armanda E. Santos. New BACE1 inhibitors decrease Aß production and accumulation in the 3xTg-AD model. 13th International Conference on Alzheimer¿s and Parkinson¿s Diseases (ADPD 2017). Vienna, Austria.
2016/12/08 - 2016/12/10 Poster presentation: Rosa Resende, Marisa Ferreira-Marques, Teresa Dinis, Cláudia Pereira, Armanda E. Santos. New BACE1 inhibitors decrease Aß production and accumulation in the 3xtg-AD mouse model. XIX National Congress of Biochemistry. Guimarães, Portugal.
2016/09/30 - 2016/09/30 Poster presentation: Rosa Resende, Marisa Ferreira-Marquesa, Teresa Dinis, Cláudia Pereira, Armanda E. Santos. New BACE1 inhibitors decrease Aß production and accumulation in the 3xtg-AD mouse model. 1st Symposium on Aging Research @CNC. Coimbra, Portugal.
2015/10/05 - 2015/10/09 Quantitative Fluorescence Microscopy Advanced Course.
Oficina (workshop)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2015/07/12 - 2015/07/17 Poster presentation: Marisa Ferreira-Marquesa, Rosa Resende*, Cláudia Pereira, Teresa Dinis, Armanda E. Santos. New BACE1 inhibitors for Alzheimer’s disease treatment. 19th European Symposium of Organic Chemistry- ESOCXIX. Lisbon, Portugal. July, 12th-17th. *These authors contributed equally to this study
2015/07/16 - 2015/07/16 Workshop "Bioestatística para trabalhos de investigação."
Oficina (workshop)
Universidade de Coimbra, Portugal
2015/06/04 - 2015/06/05 Poster presentation: Marisa Ferreira-Marquesa, Rosa Resende*, Cláudia Pereira, Teresa Dinis, Armanda E. Santos. Tackling Alzheimer’s Disease (AD) with a new inhibitor of BACE1: evaluation of compound efficiency in vitro and in an in vivo model of AD. XIV Meeting of the Portuguese Society for Neuroscience. Póvoa do Varzim, Portugal. *These authors contributed equally to this study
2012 - 2015 National Scientific Programme "Ciência Viva - ocupação científica dos jovens nas férias". Summer laboratory activities with High School students. Ciência Viva – ocupação científica dos jovens nas férias
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014/12/17 - 2014/12/20 Poster presentation: Marisa Ferreira*, Rosa Resende*, Cláudia Pereira, Teresa Dinis, Armanda Santos. Tackling Alzheimer’s disease with a new inhibitor of BACE1: evaluation of compound efficacy in vitro and in a cellular model of Alzheimer’s disease. XVIII Congress of the Portuguese Biochemical Society. Coimbra, Portugal. * These authors contributed equally.
2014/11/07 - 2014/11/08 Workshop "Profiling alterations in microglia dynamic properties by neuroinflammation."
Oficina (workshop)
iMed.Ulisboa. Faculdade de Farmácia da Universidade de Lisboa, Portugal
2013/05/23 - 2013/05/23 Workshop "Grant writing and funding opportunities”.
Oficina (workshop)
2012/06/18 - 2012/06/22 4th Course on Optical Microscopy Imaging for Biosciences.
Oficina (workshop)
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2011/05/23 - 2011/05/26 Biostatistics Course (Prof Pedro Oliveira ICBAS -Porto). PDBEB
Oficina (workshop)
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2010/12/15 - 2010/12/17 Poster presentation: Isaura Martins, Sílvia Gomes, Rui O Costa, Rosa Resende, Catarina Resende Oliveira, Cláudia MF Pereira. Ghrelin and leptin protect hippocampal neurons against Aß-induced toxicity. Relevance for therapeutic intervention in Alzheimer’s disease. XVII National Congress of the Portuguese Biochemical Society. Porto, Portugal.
2010/11/29 - 2010/12/03 “Image processing and analysis in cell physiology.” Advanced Training Workshop.
Oficina (workshop)
Universidade de Aveiro, Portugal
2010/11/28 - 2010/11/30 Poster presentation: Isaura Martins, Sílvia Gomes, Rui O Costa, Rosa Resende, Catarina Resende Oliveira, Cláudia MF Pereira. Ghrelin and leptin protect hippocampal neurons and hypothalamic cells against Aß-induced toxicity. Relevance for therapeutic intervention in Alzheimer’s disease. 2nd National Meeting on Medicinal chemistry. Coimbra, Portugal.
2010/05/06 - 2010/05/08 Poster presentation: Isaura Martins, Sílvia Gomes, Rui O Costa, Rosa Resende, Cláudia MF Pereira. Leptin and ghrelin protect against Aß-induced toxicity in hippocampal and hypothalamus neurons. 2010 Annual ENINET Meeting. Coimbra, Portugal.
2010 - 2010 Participation in Euroskills 2010 Exhibition as a representative of Centro de Neurociências de Coimbra. "Ciência ao vivo". 9th-12th December. Lisboa.
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2009/09/07 - 2009/09/18 Course in Laboratory Animal Science (Accredited by FELASA, category C) organized by the Laboratory Animal Science group, Institute for Molecular and Cell Biology. DGV License 19/10/2009).
Outro
Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal
2009 - 2009 Science and Technology Portuguese Week. Participation and organization of laboratory activities with High School students.
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2008/07/26 - 2008/07/31 Poster presentation: Resende R, Moreira PI, Deshpande A, Busciglio J, Pereira C, Oliveira CR. Increased oxidative stress is an early pathological feature in 3xTg-AD mice. 11th International Conference on Alzheimer’s Disease and Related Disorders. Chicago, USA.
2008/07/26 - 2008/07/31 Poster presentation: Pereira C, Ferreiro E, Costa R, Resende R, Cardoso S, Oliveira CR. Cross-talk between endoplasmic reticulum and mitochondria in the neurotoxicity induced by Alzheimer’s disease-associated beta-amyloid peptide. 11th International Conference on Alzheimer’s Disease and Related Disorders. Chicago, USA.
2004 - 2008 National Scientific Programme “Ciência Viva – ocupação científica dos jovens nas férias”. Summer laboratory activities with High School students. Ciência Viva – ocupação científica dos jovens nas férias
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2007/11/08 - 2007/11/11 Poster presentation: Ferreiro E., Costa R., Resende R., Oliveira C.R., Pereira C. "Communication between endoplamic reticulum and mitochondria in the neuronal death induced by amyloid-beta peptide". Fifth International Congress on Vascular Dementia. Budapest, Hungary. November, 8th-11 th.
2007/11/08 - 2007/11/08 Poster presentation: Pereira C., Fonseca A.C., Resende R., Ferreiro E., Oliveira C.R. Statins prevent beta-amyloid-induced toxicity in cortical neurons. Fifth International Congress on Vascular Dementia. Budapest, Hungary.
2007/09/19 - 2007/09/22 Workshop Science Comunication 2007.
Oficina (workshop)
2007/05/23 - 2007/05/26 Poster presentation: Rosa Resende, Elisabete Ferreiro, Catarina Resende Oliveira, Cláudia Pereira. Endoplasmic Reticulum stress induced by Aß1-42 oligomers leads to GSK3ß-mediated tau phosphorylation. 10th Meeting of the Portuguese Society for Neurosciences. Ofir, Portugal. May, 23rd-26th.
2007/05/23 - 2007/05/26 Poster presentation: Rosa Resende, Elisabete Ferreiro, Catarina Resende Oliveira, Cláudia Pereira. Endoplasmic Reticulum stress induced by Aß1-42 oligomers leads to GSK3ß-mediated tau phosphorylation. 10th Meeting of the Portuguese Society for Neurosciences. Ofir, Portugal.
2007/05/23 - 2007/05/26 Poster presentation: Fonseca AC, Resende R, OliveiraCR, Pereira C. Effect of statins on beta-amyloid-induced cortical neurotoxicity. 10th Meeting of the Portuguese Society for Neurosciences. Ofir, Portugal.
2006/12/08 - 2006/12/10 Poster presentation: Rosa Resende, Márcio Baptista, Cláudia Pereira, Catarina Oliveira. Role of Glycogen synthase kinase-3ß in tau phosphorylation induced by amyloid- beta oligomers. XV Congress of the Portuguese Biochemical Society. Aveiro, Portugal.
2006/12/08 - 2006/12/10 Poster presentation: Rosa Resende, Márcio Baptista, Cláudia Pereira, Catarina Oliveira. Role of Glycogen synthase kinase-3ß in tau phosphorylation induced by amyloid- beta oligomers. XV Congress of the Portuguese Biochemical Society. Aveiro, Portugal.
2006/10/14 - 2006/10/18 Poster presentation: RM Resende, M Baptista, C Pereira, CR Oliveira. Glycogen synthase kinase-3ß is involved in tau phosphorylation induced by different Aß assemblies. Society for Neuroscience 36th annual meeting. Atlanta, Georgia, USA.
2006/07/15 - 2006/07/20 Poster presentation: Rosa Resende, Márcio Baptista, Cláudia Pereira, Catarina Oliveira. In vitro study of amyloid-ß peptide toxicity. The role of physical state. The 10th International Conference on Alzheimer’s Disease and Related Disorders. Madrid, Spain, July, 15th -20th.
2006 - 2006 Science and Technology Portuguese Week. Participation and organization of laboratory activities with High School students.
Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2005/11/12 - 2005/11/16 Poster presentation: A Despande, R Resende, P Helguera, S Oddo, I Smith, F LaFerla, J Busciglio. Mitochondrial dysfunction and transport deficits in 3xTG-AD mice. Society for Neuroscience 35th Annual Meeting 2005. Washington DC, USA, November, 12th -16th.
2005/11/11 - 2005/11/11 Workshop “Writing, editing and publishing in science”. Society for Neuroscience 35th Annual Meeting. Washington DC, USA
2005/05 - 2005/11 Short-Visiting PhD student, Department of Neurobiology and Behavior, School of Biological Sciences, University of California, USA Project: “Study of mitochondrial dysfunction and transport deficits in a triple transgenic model of Alzheimer’s disease (3xTg-AD).” Supervisor: Professor Jorge Busciglio (PhD).
Outro
2005/05/19 - 2005/05/20 Poster presentation: Elisabete Ferreiro, Rosa Resende, Catarina Resende de Oliveira, Cláudia Pereira, “Mechanism of amyloid-beta induced early synaptotoxicity”, Reunião da Sociedade Portuguesa de Neurociências (Portuguese Society for Neurosciences). Luso, Portugal.
2004/12/02 - 2004/12/04 Poster presentation: Rosa Resende, Catarina R. Oliveira, Cláudia Pereira. The effect of the ß-sheet content on amyloid-beta toxicity. XIV Congress of the Portuguese Biochemical Society. Vilamoura, Portugal.
2004/10/23 - 2004/10/27 Poster presentation: R.M. Resende, E.B. Ferreiro, C.M.F. Pereira, C.R. Oliveira. The role of endoplasmic reticulum in amyloid-beta-induced synaptotoxicity. Society for Neuroscience 34th Annual Meeting 2004. San Diego, US.
2004/07/17 - 2004/07/23 “New molecular strategies to treat neurodegenerative diseases. Lecture course (FEBS).
Outro
2004/07/17 - 2004/07/23 Poster presentation: R. Resende, C. Oliveira, C. Pereira. The influence of the aggregation state on the neurotoxicity of amyloid-beta peptides. “Mew molecular strategies to treat neurodegenerative diseases”. FEBS Course. Ofir, Portugal.
2004/07/10 - 2004/07/14 Poster presentation: R. Resende, C. Pereira, C. R. Oliveira. Synaptotoxicity mediated by amyloid-beta peptides. 4th Forum of European Neuroscience (FENS), Lisbon, Portugal.
2004/06/25 - 2004/06/28 Poster presentation: E. Ferreiro, R. Resende, C. Resende de Oliveira, C. Pereira. Endoplasmic reticulum-mediated apoptosis induced by Abeta peptide. The 15th International Cell Death Symposium on “The Mechanisms of Cell Death”. Maynooth, Ireland.
2003/12/19 - 2003/12/19 Workshop “Pieces and parts: a primer on brain dissection from discrete regions to micronuclei”.
Oficina (workshop)
Universidade de Aveiro, Portugal
2003/10/25 - 2003/10/28 Poster presentation: R. Resende, E. Ferreiro, C. Pereira, C. R. Oliveira. Levels of synaptic protein markers under apoptotic-like conditions. 11th Euroconference on Apoptosis. Ghent, Belgium.
2003/06/13 - 2003/06/14 Poster presentation: J. B. Melo, C. Pereira, R. Resende, P. Agostinho, C. R. Oliveira. The aggregation state of Amyloid-beta and Prion peptides vs neurotoxicity. 17th Meeting of the Portuguese Group of Studies on Aging and Dementia. Grande Hotel da Curia, Curia, Portugal.
2003/06/12 - 2003/06/13 Poster presentation: R. Resende, E. Ferreiro, C. Pereira, C. R. Oliveira. Cortical neuron apoptosis induced by tumor necrosis factor-a (TNF-a), staurosporine, thapsigargin and beta-amyloid peptide 1-40 (Abeta1-40). 8th Meeting of the Portuguese Society for Neuroscience. Curia, Portugal.
2003/05/26 - 2003/06/01 “Frontiers in neurodegenerative disorders and aging: fundamental aspects, clinical perspectives and new insights”. Lecture course (FEBS). Antalya, Turkey
Outro
2002/09/12 - 2002/09/13 Workshop “Novel therapeutic opportunities in Neurodegenerative disease.”
Oficina (workshop)
Universidade de Aveiro, Portugal
2001/09/04 - 2001/09/14 “Protein Biology: from synthesis to function and disease”. Lecture course (FEBS) Spetses, Greece
Outro
2000/11/09 - 2000/11/11 Poster presentation: Paula Veríssimo, R. Andrade, R. Resende, L. Cortes, A. Todo-Bom, C. Faro, E. Pires. Enzymatic characterisation of a serine protease isolated from pollen of Parietaria judaica potentially involved in allergic response. II Congresso de Investigação em Medicina (2nd Meeting of Medicine Research). Coimbra, Portugal.
2000/10/28 - 2000/10/30 Poster presentation: Rosa Resende, Paula Veríssimo, Carlos Faro and Euclides Pires. Serine protease from Parietaria judaica pollen causes epithelial injury. XII Congress of the Portuguese Biochemical Society. Póvoa do Varzim, Portugal.
2000/10/28 - 2000/10/30 Poster presentation: Conceição Egas, Nuno Lavoura, Rosa Resende, Euclides Pires, Maria C. Pedroso de Lima and Carlos Faro. Recombinant PSI is a potent inducer of vesicle leakage. XII Congress of the Portuguese Biochemical Society. Póvoa do Varzim, Portugal.
2000/04/10 - 2000/04/14 “Organotypic culture of hippocampal slices” Lecture and pratical course (prof Birthe Jakobsen).
Oficina (workshop)
Universidade de Coimbra, Portugal
1999/11/28 - 1999/11/30 Poster presentation: Margarida Vieira, A. Mendes, R. Andrade, R. Resende, E. Pires, C. Faro. Cloning and Expression of Cardosins A and B from the Cardoon Cynara cardunculus L. XI Congress of the Portuguese Biochemical Society. Tomar, Portugal.

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2023/10/13 Impact of chronic stress on astrocytic K+ channels, Kir4.1, and their interactions with AQP4 channels: modulation by adenosine A2A receptors.
Arguente principal
Ana Margarida Moreira Nabais (Mestrado)
Universidade de Coimbra Faculdade de Medicina, Portugal
2023/07/20 Avaliação in vitro de derivados da curcumina de síntese, em modelo celular da doença de Alzheimer
Arguente principal
Sabrina Louise Lopes Pereira (Outro)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2022/11/11 Influence of HDAC inhibitors on behavior and gene expression in models of Alzheimer’s disease.
Arguente principal
Rodrigo de Azevedo Arrochela Taveira (Mestrado)
Universidade do Porto Faculdade de Medicina, Portugal
2022/09/16 Internship Reports and Monograph Entitled" Molecular mechanisms involved in the beneficial effects of physical exercise on brain function/ prevention of neurodegenerative diseases"
Arguente principal
Mariana Folhinha Martins (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/12/16 Evaluation of the Ability of CIAD7, a Natural Compound, to Induce the Pro-Resolution Phenotype in Murine Macrophages.
Arguente principal
Inês Alexandra Ferreira Rodrigues (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/12/15 Skin allergens: molecules with a possible application in Alzheimer's disease
Arguente principal
Jéssica Maria Pinto Macedo (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2021/12/06 Perturbation of ER-mitochondria crosstalk in bipolar disorder: effect of Sigma-1 receptor modulation
Orientador
Ana Rita Azevedo Henriques da Cunha (Mestrado)
Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal
2019/07/26 Desregulação da proteóstase e comunicação intercelular na doença de Alzheimer. A indução de stresse intracellular afeta a comunicação neurónio-microglia?
Arguente principal
Vanessa Jorge Moço (Outro)
Instituto Politécnico de Coimbra Escola Superior Agrária de Coimbra, Portugal
2019 Mitochondrial respiratory chain complexes and antioxidante enzymes analysis in diabetes and chronic peridontitis-derived human blood mononuclear cells.
Arguente principal
Olga Fokt (Mestrado)
Faculdade de Medicina, Universidade de Coimbra, Portugal
2016 Identificação e Quantificação de Gangliósidos em Cérebro de Modelos Animais de Doença de Alzheimer: um Estudo Lipidómico
Arguente principal
CATARINA LUÍSA DA SILVA LOPES E CAMPOS DE OLIVEIRA (Mestrado)
Universidade de Aveiro, Portugal
2015 Role of oxygen species in inflammasome activation in microglia under stress conditions
Orientador
Rafael Azevedo Dias (Mestrado)
Faculdade de Medicina, Universidade de Coimbra, Portugal

Curso / Disciplina lecionado

Disciplina Curso (Tipo) Instituição / Organização
2024/02/26 - 2024/02/26 Laboratory practical classes of the Mechanisms of neuronal dysfunction and neurodegeneration course unit. Master Course in Molecular and Translational Neuroscience. Faculty of Medicine, University of Coimbra. Mechanisms of neuronal dysfunction and neurodegeneration (Mestrado) Faculdade de Medicina, Universidade de Coimbra, Portugal
2024/02/12 - 2024/02/16 Pathogenic Mechanisms in Neuropsychiatric and Neurodegenerative Disorders. https://cnc.uc.pt/en/pdbeb/beb-advanced-courses/pdbeb-courses-20232024-pathogenic-mechanisms-in-neuropsychiatric-and-neurodegenerative-disorders (Doutoramento) Universidade de Coimbra, Portugal
2023/11/09 - 2023/12/18 Laboratory practical classes of the Applied Research I course unit. Integrated Master in Medicine. Faculty of Medicine, University of Coimbra (2023/2024) Investigação Aplicada I (Mestrado integrado) Faculdade de Medicina, Universidade de Coimbra, Portugal
2023/11/20 - 2023/12/07 Practical and theoretical-practical classes of the Integrative Multidisciplinar Research Project course unit. Master Course in Biomedical Research. Faculty of Medicine, University of Coimbra. Projeto Integrado Multidisciplinar (Mestrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2023/10/25 - 2023/10/25 Practical classe of Research Methods and Techniques subject. Master in Biomedical Research. Faculty of Medicine, University of Coimbra Métodos e Técnicas de Investigação Faculdade de Medicina, Universidade de Coimbra, Portugal
2023/10/09 - 2023/10/11 Laboratory practical classes of the Cell Regulation subject. Master Course in Biomedical Research. Faculty of Medicine, University of Coimbra Regulação Celular (Mestrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2023/03/09 - 2023/05/11 Laboratory practical classes of the Applied Research II course unit. Integrated Master in Medicine. Faculty of Medicine, University of Coimbra (2021/2022) Investigação Aplicada II (Mestrado integrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2023/03/07 - 2023/03/07 Laboratory practical classes of the Mechanisms of neuronal dysfunction and neurodegeneration course unit. Master Course in Molecular and Translational Neuroscience. Faculty of Medicine, University of Coimbra. Mechanisms of neuronal dysfunction and neurodegeneration (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2023/01/30 - 2023/02/03 Neuroscience - From Synapses to Circuits and Brain Diseases (Module 3 - Pathogenic Mechanisms in Neuropsychiatric and Neurodegenerative Disorders) (Doutoramento) Universidade de Coimbra, Portugal
2022/11/28 - 2022/12/16 Laboratory practical classes of the Integrative Multidisciplinar Research Project course unit. Master Course in Biomedical Research. Faculty of Medicine, University of Coimbra. Projeto Integrado Multidisciplinar (Mestrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2022/09/26 - 2022/10/07 Laboratory practical classes of the Cell Regulation subject. Master Course in Biomedical Research. Faculty of Medicine, University of Coimbra Regulação Celular (Mestrado) Universidade de Coimbra Faculdade de Medicina, Portugal
2022/03/03 - 2022/05/19 Laboratory practical classes of the Applied Research II course unit. Integrated Master in Medicine. Faculty of Medicine, University of Coimbra (2021/2022) Mestrado Integrado em Medicina Faculdade de Medicina, Universidade de Coimbra, Portugal
2022/03/08 - 2022/03/08 Laboratory practical classes of the Mechanisms of neuronal dysfunction and neurodegeneration course unit. Master Course in Molecular and Translational Neuroscience. Faculty of Medicine, University of Coimbra. Mechanisms of neuronal dysfunction and neurodegeneration Faculdade de Medicina, Universidade de Coimbra, Portugal
2021/10/11 - 2021/10/12 Laboratory practical classes of the Cell Regulation course unit. Master Course in Biomedical Research. Faculty of Medicine, University of Coimbra. Regulação Celular (Mestrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2021/03/02 - 2021/03/02 Laboratory practical classes of the Mechanisms of neuronal dysfunction and neurodegeneration course unit. Master Course in Molecular and Translational Neuroscience. Faculty of Medicine, University of Coimbra. Mechanisms of neuronal dysfunction and neurodegeneration (Mestrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2020/10/29 - 2020/12/17 Laboratory practical classes of the Applied Research I course unit. Integrated Master in Medicine. Faculty of Medicine, University of Coimbra (2020/2021) Investigação Aplicada I (Mestrado integrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2020/02 - 2020/05 Laboratory practical classes of the Applied Research II course unit. Integrated Master in Medicine. Faculty of Medicine, University of Coimbra (2019/2020) Investigação Aplicada II (Mestrado integrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2019/12/05 - 2019/12/19 Laboratory practical classes of the Integrative Multidisciplinar Research Project course unit. Master Course in Biomedical Research. Faculty of Medicine, University of Coimbra. Projeto Integrado Multidisciplinar (Mestrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2019/10 - 2019/12 Laboratory practical classes of the Applied Research I course unit. Integrated Master in Medicine. Faculty of Medicine, University of Coimbra (2019/2020) Investigação Aplicada I (Mestrado integrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2016/10 - 2017/12 Laboratory practical classes of the Applied Research III course unit. Integrated Master in Medicine. Faculty of Medicine, University of Coimbra (2015/2016) Mestrado Integrado Universidade de Coimbra, Faculdade de Medicina, Portugal
2015/10 - 2016/12 Laboratory practical classes of the Applied Research III course unit. Integrated Master in Medicine. Faculty of Medicine, University of Coimbra (2015/2016) Investigação Aplicada III (Mestrado integrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2015/10 - 2016/12 Laboratory practical classes of the Applied Research I course unit. Integrated Master in Medicine. Faculty of Medicine, University of Coimbra (2015/2016) Investigação Aplicada I (Mestrado integrado) Universidade de Coimbra, Faculdade de Medicina, Portugal
2013/12 - 2013/12 Theoretical class of the neurobiology I course unit . Integrated Master in Biomedical Engineering. Faculty of Sciences, University of Coimbra (2013/2014) Neurobiologia I (Mestrado integrado) Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal

Entrevista / Programa (rádio / tv)

Programa Tema
2023/04/02 - 2023/04/02 Olhó Robot - Rádio Universidade de Coimbra (RUC) Esquizofrenia

Membro de associação

Nome da associação Tipo de participação
2019 - Atual European Calcium Society Member
2017 - Atual Grupo de Estudos de Envelhecimento Cerebral e Demência (GEECD) Member
2004 - Atual Portuguese Society for Neurosciences (SPN) - FENS member Member

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2013 - 2022 papers revision: Molecular Psychiatry, Life Sciences, Brain Research, Front. Aging Neurosci., Current Pharmaceutical Design, International Journal of Alzheimer's Disease, British Journal of Pharmacology, J. Biochemistry Research, J. Pharmacological Sciences, J. of Sports Sciences, J. of Experimental Neuroscience, Journal of Neurochemical Research, Journal of Alzheimers Disease, Journal of Neuroendocrinology, BioMed Research International, PeerJ, Experimental Gerontology, journal of Neurochemistry, Neurochemistry International.
2017/04/26 - 2017/06/02 Member of the jury, 25º Concurso Jovens Cientistas promoted by Fundação da Juventude e Ciência Viva Ciência Viva, Portugal
2015 - 2015 Evaluation Of Research Proposals Italian Ministry of Health – General Direction for Scientific Research and Health Innovation , Itália
2014/04 - 2014/04 Evaluation of applications for a Research Assistant position (BIM) under the project PTDC/NEU-SCC/1351/2012, funded by FCT Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2014 - 2014 Research proposals BRACE – Funding Research into Alzheimer’s, Reino Unido
2013/07/25 - 2013/07/25 Exendin-4 therapy in Alzheimer¿s disease and diabetic brain: effect in mitochondria and insulin-mediated pathways. PhD project defense - Emanuel Monteiro Candeias Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2013 - 2013 PhD project in Biomedicine and Experimental Biology (BEB), Center for Neuroscience and Cell Biology, Univ. Coimbra. Exendin-4 therapy in Alzheimer’s disease and diabetic brain: effect in mitochondria and insulin-mediated pathways. Emanuel Monteiro Candeias (25th July) Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal
2012/11 - 2012/12 Evaluation of applications for a BI Fellowship under the project PTDC/SAU-TOX/117481/2010, funded by FCT Universidade de Coimbra Centro de Neurociências e Biologia Celular, Portugal

Tutoria

Tópico Nome do aluno
2024/01/22 - 2024/02/16 Role of cellular senescence in bipolar disorder and schizophrenia. The importance of communication between the endoplasmic reticulum and mitochondria. Maria Assunção Piloto
2023/05/22 - 2023/06/09 Cellular stress response in mental disorders. Ânia Isabel Correia Rodrigues
2021/12/06 - 2021/12/17 Cell Senescence in Schizophrenia Angela Soares , Filomena Oliveira , João Martins , Laura Nóbrega , Rita Pais
2021/09/01 - 2021/09/30 Mecanismos de controlo de qualidade em doenças neuropsiquiátricas Beatriz Marques
2021/07/19 - 2021/08/13 Investigação em Neurociências: estudar a fisiopatologia de doenças psiquiátricas usando amostras obtidas de doentes. Rodrigo Campaniço
2020/12/02 - 2020/12/18 Mitochondrial dysfunction in skin fibroblasts of bipolar patients: dynamics, biogenesis and mitophagy. Guilherme Faria; Joana Margarido; Rita Gageiro
2020/10/06 - 2020/10/19 Mitochondrial Dysfunction in Fibroblasts from Patients with Bipolar Disease. Catarina Mestre, Inês Morgado, Guilherme Rego, Francisco Duarte.
2020/01/05 - 2020/02/05 Hipótese das MAM na Doença Bipolar: Homeostase do Cálcio. Mariana Pires
2019/01/21 - 2020/01/20 Tânia Fernandes
2020 - 2020 Resposta ao Stresse do Retículo endoplasmático na doença Bipolar. Ana Carolina Real
2019 - 2019 Comunicação retículo endoplasmático-mitocôndria em condições de stress celular em doentes bipolares. Inês Moniz, Ana Carolina Real, Guilherme Farias
2019 - 2019 Podem as "MAM" ajudar na doença Bipolar? Maria cardoso
2019 - 2019 Endoplasmic reticulum (ER) responses to stress during the initial stages of Bipolar disorder. Raquel Pinto
2017/11/10 - 2018/05/09 Patrícia Raquel Reis Moreira
2018 - 2018 Targeting BACE1 for Alzheimer’s disease therapy. Andreia Cunha.
2017 - 2018 Rémy Cardoso
2017/02/10 - 2017/02/16 Nádia Ramos
2017/02/10 - 2017/02/16 Nancy Marques
2017 - 2017 New peptide inhibitors of BACE1: Towards Alzheimer's disease treatment. Ana Catarina Pereira
2017 - 2017 Joana Marinheira
2016/10 - 2016/12 Resposta ao Stresse e comunicação intercelular em doenças neurodegenerativas. Mariana Araújo
2016 - 2016 In vitro and in vivo evaluation of new BACE1 inhibitors Carolina Vinagreiro
2016 - 2016 Development of new inhibitor of BACE1: a hope to delay Alzheimers disease? Cátia Lopes, Jéssica Costa, João Medeiros, Mariana Gomes
2016 - 2016 Estudo de um novo inibidor da BACE1: diminuição da produção do peptídeo amilóide no cérebro de murganhos 3xTg-AD. Miguel Lemos
2016 - 2016 Mariana Catarina Amado Trindade Marques
2015/11/16 - 2015/12/18 The new BACE1 inhibitor ameliorates Aß pathology in cellular and animal models of AD Mariana Manso
2014/05/01 - 2015/11/30 Marisa Ferreira Marques
2015 - 2015 The new BACE1 inhibitor ameliorates Aß pathology in aged 3xTg-AD mice. Ana Rita Mendes
2015 - 2015 The new BACE1 inhibitor ameliorates Aß pathology in aged 3xTg-AD mice. Carla Marques
2015 - 2015 The new BACE1 inhibitor ameliorates Aß pathology in aged 3xTg-AD mice. Miguel Lemos
2015 - 2015 Estudo de potenciais alvos terapêuticos na doença de Alzheimeir Yolanda Afonso
2015 - 2015 Estudo da BACE1 como alvo terapêutico para a Doença de Alzheimer. André Sousa
2015 - 2015 The new BACE1 inhibitor ameliorates Aß pathology in cellular and animal models of AD. Catarina Silva Pechincha
2013 - 2015 ER stress-induced inflammasome activation in microglia. Rafael Azevedo Dias
2014/06 - 2014/07 Tiago Rondão
2013 - 2014 Inflammasome activation in response to ER stress. Joana Brito
2013/06 - 2013/07 Susana Veloso
2013 - 2013 Cheila Daniela Andrade Batista
2009/09 - 2010/07 Toxicity of amyloid-beta peptide in hypothalamic cells and protection by leptin and ghrelin. Implications for the etiopathogenesis of Alzheimer’s disease. Sílvia Gomes
2009/09 - 2010/07 Neuroprotection by leptin and ghrelin against amyloid-beta toxicity in hippocampal neurons. Relevance for therapeutic intervention in Alzheimer’s disease Isaura Martins
2006/09 - 2007/07 Sueli Marques
2005/12 - 2006/07 Neuroprotective effects of statins in an in vitro model of Alzheimer's disease Ana Catarina Fonseca
2005/12 - 2006/07 Márcio Paulo Simões Baptista
Distinções

Prémio

2017 Bolsa de Investigação Edgar Cruz e Silva
Santa Casa da Misericórdia de Lisboa, Portugal

Outra distinção

2009 Project for Brain Awarness Week: Exercising our senses. Fitning our brain.
Federation of European Neuroscience Societies, Bélgica