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Becq Frédéric. Published 130 articles in journals. Works in the area(s) of Natural sciences with emphasis on Biological Sciences with emphasis on Molecular Biology. In his curriculum Ciência Vitae the most frequent terms in the context of scientific, technological and artistic-cultural output are: epithelial cells; human airways; ionic channels; cystic fibrosis; CFTR; rare diseases; pharmacology; drug discovery; .
Identificação

Identificação pessoal

Nome completo
Becq Frédéric

Nomes de citação

  • Frédéric, Becq

Identificadores de autor

Ciência ID
AE1E-CD00-05FF
ORCID iD
0000-0003-3915-0973

Telefones

Telemóvel
  • (+33) 678734383 (Profissional)

Moradas

  • University of Poitiers, Batiment Pôle Biologie Santé, 1 rue Georges Bonnet, 86073, Poitiers, Poitiers, França (Profissional)

Domínios de atuação

  • Ciências Naturais - Ciências Biológicas - Biologia Molecular
Formação
Grau Classificação
1993/12/09
Concluído
 Biology (Docteur)
Aix-Marseille Université, França
Percurso profissional

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento 		Empregador
1997/10/01 - Atual Professor Catedrático (Docente Universitário) Université de Poitiers, França
Université de Poitiers UFR Sciences Fondamentales et Appliquées, França
Produções

Publicações

Artigo em revista
  1. Dehoux, C.; Castellan, T.; Enel, M.; André-Barrès, C.; Mirval, S.; Becq, F.; Ballereau, S.; Génisson, Y.. "Transalpinecine and Analogues: First Total Synthesis, Stereochemical Revision and Biological Evaluation". European Journal of Organic Chemistry (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85061068120&partnerID=MN8TOARS.
    10.1002/ejoc.201900071
  2. Kadri, L.; Ferru-Clément, R.; Bacle, A.; Payet, L.-A.; Cantereau, A.; Hélye, R.; Becq, F.; et al. "Modulation of cellular membrane properties as a potential therapeutic strategy to counter lipointoxication in obstructive pulmonary diseases". Biochimica et Biophysica Acta - Molecular Basis of Disease 1864 9 (2018): 3069-3084. http://www.scopus.com/inward/record.url?eid=2-s2.0-85049319759&partnerID=MN8TOARS.
    10.1016/j.bbadis.2018.06.021
  3. Yefimova, M.; Bourmeyster, N.; Becq, F.; Burel, A.; Lavault, M.-T.; Jouve, G.; Veau, S.; et al. "Update on the cellular and molecular aspects of cystic fibrosis transmembrane conductance regulator (CFTR) and male fertility,CFTR et fertilité masculine : aspects cellulaires et moléculaires". Morphologie (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85057798856&partnerID=MN8TOARS.
    10.1016/j.morpho.2018.11.001
  4. Froux, L.; Billet, A.; Becq, F.. "Modulating the cystic fibrosis transmembrane regulator and the development of new precision drugs". Expert Review of Precision Medicine and Drug Development 3 6 (2018): 357-370. http://www.scopus.com/inward/record.url?eid=2-s2.0-85058812803&partnerID=MN8TOARS.
    10.1080/23808993.2018.1547109
  5. Farhat, R.; El-Seedy, A.; Sari, A.I.P.; Norez, C.; Pasquet, M.-C.; Becq, F.; Kitzis, A.; Ladevèze, V.. "In cellulo analyses of the p.Val322Ala mutation on the CFTR protein conformation and activity". Comptes Rendus - Biologies 340 8 (2017): 367-371. http://www.scopus.com/inward/record.url?eid=2-s2.0-85026774456&partnerID=MN8TOARS.
    10.1016/j.crvi.2017.06.001
  6. Philippe, R.; Antigny, F.; Buscaglia, P.; Norez, C.; Huguet, F.; Castelbou, C.; Trouvé, P.; et al. "Calumenin contributes to ER-Ca2+homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention". Cell Calcium 62 (2017): 47-59. http://www.scopus.com/inward/record.url?eid=2-s2.0-85011890610&partnerID=MN8TOARS.
    10.1016/j.ceca.2017.01.011
  7. Billet, A.; Froux, L.; Hanrahan, J.W.; Becq, F.. "Development of automated patch clamp technique to investigate CFTR chloride channel function". Frontiers in Pharmacology 8 APR (2017): http://www.scopus.com/inward/record.url?eid=2-s2.0-85018780112&partnerID=MN8TOARS.
    10.3389/fphar.2017.00195
  8. Meijer, L.; Nelson, D.J.; Riazanski, V.; Gabdoulkhakova, A.G.; Hery-Arnaud, G.; Le Berre, R.; Loaëc, N.; et al. "Modulating Innate and Adaptive Immunity by (R)-Roscovitine: Potential Therapeutic Opportunity in Cystic Fibrosis". Journal of Innate Immunity 8 4 (2016): 330-349. http://www.scopus.com/inward/record.url?eid=2-s2.0-84961138270&partnerID=MN8TOARS.
    10.1159/000444256
  9. Yefimova, M.G.; Béré, E.; Cantereau-Becq, A.; Harnois, T.; Meunier, A.-C.; Messaddeq, N.; Becq, F.; Trottier, Y.; Bourmeyster, N.. "Myelinosomes act as natural secretory organelles in Sertoli cells to prevent accumulation of aggregate-prone mutant Huntingtin and CFTR". Human molecular genetics 25 19 (2016): 4170-4185. http://www.scopus.com/inward/record.url?eid=2-s2.0-85021853262&partnerID=MN8TOARS.
    10.1093/hmg/ddw251
  10. Chevaleyre, C.; Riou, M.; Bréa, D.; Vandebrouck, C.; Barc, C.; Pezant, J.; Melo, S.; et al. "The pig: A relevant model for evaluating the neutrophil serine protease activities during acute pseudomonas aeruginosa lung infection". PLoS ONE 11 12 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-85006427674&partnerID=MN8TOARS.
    10.1371/journal.pone.0168577
  11. Nocquet, P.-A.; Hensienne, R.; Wencel-Delord, J.; Laigre, E.; Sidelarbi, K.; Becq, F.; Norez, C.; Hazelard, D.; Compain, P.. "Pushing the limits of catalytic C-H amination in polyoxygenated cyclobutanes". Organic and Biomolecular Chemistry 14 9 (2016): 2780-2796. http://www.scopus.com/inward/record.url?eid=2-s2.0-84983140462&partnerID=MN8TOARS.
    10.1039/c5ob02602d
  12. Ferru-Clément, R.; Spanova, M.; Dhayal, S.; Morgan, N.G.; Hélye, R.; Becq, F.; Hirose, H.; et al. "Targeting surface voids to counter membrane disorders in lipointoxication-related diseases". Journal of Cell Science 129 12 (2016): 2368-2381. http://www.scopus.com/inward/record.url?eid=2-s2.0-84976494266&partnerID=MN8TOARS.
    10.1242/jcs.183590
  13. Bertrand, J.; Dannhoffer, L.; Antigny, F.; Vachel, L.; Jayle, C.; Vandebrouck, C.; Becq, F.; Norez, C.. "A functional tandem between transient receptor potential canonical channels 6 and calcium-dependent chloride channels in human epithelial cells". European Journal of Pharmacology 765 (2015): 337-345. http://www.scopus.com/inward/record.url?eid=2-s2.0-84941569406&partnerID=MN8TOARS.
    10.1016/j.ejphar.2015.08.005
  14. Cendret, V.; Legigan, T.; Mingot, A.; Thibaudeau, S.; Adachi, I.; Forcella, M.; Parenti, P.; et al. "Synthetic deoxynojirimycin derivatives bearing a thiolated, fluorinated or unsaturated N-alkyl chain: Identification of potent a-glucosidase and trehalase inhibitors as well as F508del-CFTR correctors". Organic and Biomolecular Chemistry 13 43 (2015): 10734-10744. http://www.scopus.com/inward/record.url?eid=2-s2.0-84946615908&partnerID=MN8TOARS.
    10.1039/c5ob01526j
  15. Philippe, R.; Antigny, F.; Buscaglia, P.; Norez, C.; Becq, F.; Frieden, M.; Mignen, O.. "SERCA and PMCA pumps contribute to the deregulation of Ca<sup>2+</sup> homeostasis in human CF epithelial cells". Biochimica et Biophysica Acta - Molecular Cell Research 1853 5 (2015): 892-903. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923115914&partnerID=MN8TOARS.
    10.1016/j.bbamcr.2015.01.010
  16. Vachel, L.; Norez, C.; Jayle, C.; Becq, F.; Vandebrouck, C.. "The low PLC-d1 expression in cystic fibrosis bronchial epithelial cells induces upregulation of TRPV6 channel activity". Cell Calcium 57 1 (2015): 38-48. http://www.scopus.com/inward/record.url?eid=2-s2.0-84922610640&partnerID=MN8TOARS.
    10.1016/j.ceca.2014.11.005
  17. Sharma, H.; Jollivet Souchet, M.; Callebaut, I.; Prasad, R.; Becq, F.. "Function, pharmacological correction and maturation of new Indian CFTR gene mutations". Journal of Cystic Fibrosis 14 1 (2015): 34-41. http://www.scopus.com/inward/record.url?eid=2-s2.0-84918801046&partnerID=MN8TOARS.
    10.1016/j.jcf.2014.06.008
  18. Ferru-Clément, R.; Fresquet, F.; Norez, C.; Métayé, T.; Becq, F.; Kitzis, A.; Thoreau, V.. "Involvement of the Cdc42 pathway in CFTR post-translational turnover and in its plasma membrane stability in airway epithelial cells". PLoS ONE 10 3 (2015): http://www.scopus.com/inward/record.url?eid=2-s2.0-84929467244&partnerID=MN8TOARS.
    10.1371/journal.pone.0118943
  19. Becq, F.. "Predicting CFTR activity with front-runner cystic fibrosis drugs". EBioMedicine 2 2 (2015): 100-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-84943327825&partnerID=MN8TOARS.
    10.1016/j.ebiom.2015.01.013
  20. Carre, G.; Ouedraogo, M.; Magaud, C.; Carreyre, H.; Becq, F.; Bois, P.; Supuran, C.T.; et al. "Vasorelaxation induced by dodoneine is mediated by calcium channels blockade and carbonic anhydrase inhibition on vascular smooth muscle cells". Journal of Ethnopharmacology 169 (2015): 8-17. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928496521&partnerID=MN8TOARS.
    10.1016/j.jep.2015.03.037
  21. Norez, C.; Vandebrouck, C.; Bertrand, J.; Noel, S.; Durieu, E.; Oumata, N.; Galons, H.; et al. "Roscovitine is a proteostasis regulator that corrects the trafficking defect of F508del-CFTR by a CDK-independent mechanism". British Journal of Pharmacology 171 21 (2014): 4831-4849. http://www.scopus.com/inward/record.url?eid=2-s2.0-84918832154&partnerID=MN8TOARS.
    10.1111/bph.12859
  22. Désiré, J.; Mondon, M.; Fontelle, N.; Nakagawa, S.; Hirokami, Y.; Adachi, I.; Iwaki, R.; et al. "N- and C-alkylation of seven-membered iminosugars generates potent glucocerebrosidase inhibitors and F508del-CFTR correctors". Organic and Biomolecular Chemistry 12 44 (2014): 8977-8996. http://www.scopus.com/inward/record.url?eid=2-s2.0-84908374723&partnerID=MN8TOARS.
    10.1039/c4ob00325j
  23. Benz, N.; Le Hir, S.; Norez, C.; Kerbiriou, M.; Calvez, M.-L.; Becq, F.; Trouvé, P.; Férec, C.. "Improvement of chloride transport defect by Gonadotropin-Releasing Hormone (GnRH) in cystic fibrosis epithelial cells". PLoS ONE 9 2 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84896124153&partnerID=MN8TOARS.
    10.1371/journal.pone.0088964
  24. El Chemaly, A.; Norez, C.; Magaud, C.; Bescond, J.; Chatelier, A.; Fares, N.; Findlay, I.; et al. "ANO1 contributes to Angiotensin-II-activated Ca2+-dependent Cl- current in human atrial fibroblasts". Journal of Molecular and Cellular Cardiology 68 (2014): 12-19. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894237052&partnerID=MN8TOARS.
    10.1016/j.yjmcc.2013.12.027
  25. Boinot, C.; Souchet, M.J.; Ferru-Clément, R.; Becq, F.. "Searching for combinations of small-molecule correctors to restore F508del-cystic fibrosis transmembrane conductance regulator function and processing". Journal of Pharmacology and Experimental Therapeutics 350 3 (2014): 624-634. http://www.scopus.com/inward/record.url?eid=2-s2.0-84988009573&partnerID=MN8TOARS.
    10.1124/jpet.114.214890
  26. Carré, G.; Carreyre, H.; Ouedraogo, M.; Becq, F.; Bois, P.; Thibaudeau, S.; Vandebrouck, C.; Bescond, J.. "The hypotensive agent dodoneine inhibits L-type Ca2+ current with negative inotropic effect on rat heart". European Journal of Pharmacology 728 1 (2014): 119-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-84896702568&partnerID=MN8TOARS.
    10.1016/j.ejphar.2014.01.059
  27. Jourdain, P.; Becq, F.; Lengacher, S.; Boinot, C.; Magistretti, P.J.; Marquet, P.. "The human CFTR protein expressed in CHO cells activates aquaporin-3 in a cAMP-dependent pathway: Study by digital holographic microscopy". Journal of Cell Science 127 3 (2014): 546-556. http://www.scopus.com/inward/record.url?eid=2-s2.0-84894032759&partnerID=MN8TOARS.
    10.1242/jcs.133629
  28. Payet, L.-A.; Kadri, L.; Giraud, S.; Norez, C.; Berjeaud, J.M.; Jayle, C.; Mirval, S.; et al. "Cystic fibrosis bronchial epithelial cells are lipointoxicated by membrane palmitate accumulation". PLoS ONE 9 2 (2014): http://www.scopus.com/inward/record.url?eid=2-s2.0-84896781978&partnerID=MN8TOARS.
    10.1371/journal.pone.0089044
  29. Norez, C.; Jayle, C.; Becq, F.; Vandebrouck, C.. "Bronchorelaxation of the human bronchi by CFTR activators". Pulmonary Pharmacology and Therapeutics 27 1 (2014): 38-43. http://www.scopus.com/inward/record.url?eid=2-s2.0-84892442308&partnerID=MN8TOARS.
    10.1016/j.pupt.2013.06.008
  30. Boucherle, B.; Bertrand, J.; Maurin, B.; Renard, B.-L.; Fortuné, A.; Tremblier, B.; Becq, F.; Norez, C.; Décout, J.-L.. "A new 9-alkyladenine-cyclic methylglyoxal diadduct activates wt- and F508del-cystic fibrosis transmembrane conductance regulator (CFTR) in vitro and in vivo". European Journal of Medicinal Chemistry 83 (2014): 455-465. http://www.scopus.com/inward/record.url?eid=2-s2.0-84903722958&partnerID=MN8TOARS.
    10.1016/j.ejmech.2014.06.028
  31. Compain, P.; Decroocq, C.; Joosten, A.; de Sousa, J.; Rodríguez-Lucena, D.; Butters, T.D.; Bertrand, J.; et al. "Rescue of functional CFTR channels in cystic fibrosis: A dramatic multivalent effect using iminosugar cluster-based correctors". ChemBioChem 14 15 (2013): 2050-2058. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885422576&partnerID=MN8TOARS.
    10.1002/cbic.201300312
  32. Jenkinson, S.F.; Best, D.; Saville, A.W.; Mui, J.; Martínez, R.F.; Nakagawa, S.; Kunimatsu, T.; et al. "C-branched iminosugars: a-glucosidase inhibition by enantiomers of isoDMDP, isoDGDP, and isoDAB- l -isoDMDP compared to miglitol and miglustat". Journal of Organic Chemistry 78 15 (2013): 7380-7397. http://www.scopus.com/inward/record.url?eid=2-s2.0-84881227220&partnerID=MN8TOARS.
    10.1021/jo4005487
  33. Payet, L.-A.; Pineau, L.; Snyder, E.C.R.; Colas, J.; Moussa, A.; Vannier, B.; Bigay, J.; et al. "Saturated fatty acids alter the late secretory pathway by modulating membrane properties". Traffic 14 12 (2013): 1228-1241. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887610278&partnerID=MN8TOARS.
    10.1111/tra.12117
  34. Vachel, L.; Norez, C.; Becq, F.; Vandebrouck, C.. "Effect of VX-770 (Ivacaftor) and OAG on Ca2+ influx and CFTR activity in G551D and F508del-CFTR expressing cells". Journal of Cystic Fibrosis 12 6 (2013): 584-591. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888019495&partnerID=MN8TOARS.
    10.1016/j.jcf.2013.05.008
  35. Odolczyk, N.; Fritsch, J.; Norez, C.; Servel, N.; Da Cunha, M.F.; Bitam, S.; Kupniewska, A.; et al. "Discovery of novel potent ¿F508-CFTR correctors that target the nucleotide binding domain". EMBO Molecular Medicine 5 10 (2013): 1484-1501. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884967922&partnerID=MN8TOARS.
    10.1002/emmm.201302699
  36. Billet, A.; Mornon, J.-P.; Jollivet, M.; Lehn, P.; Callebaut, I.; Becq, F.. "CFTR: Effect of ICL2 and ICL4 amino acids in close spatial proximity on the current properties of the channel". Journal of Cystic Fibrosis 12 6 (2013): 737-745. http://www.scopus.com/inward/record.url?eid=2-s2.0-84888050424&partnerID=MN8TOARS.
    10.1016/j.jcf.2013.02.002
  37. Dirami, T.; Rode, B.; Jollivet, M.; Da Silva, N.; Escalier, D.; Gaitch, N.; Norez, C.; et al. "Missense mutations in SLC26A8, encoding a sperm-specific activator of CFTR, are associated with human asthenozoospermia". American Journal of Human Genetics 92 5 (2013): 760-766. http://www.scopus.com/inward/record.url?eid=2-s2.0-84877582299&partnerID=MN8TOARS.
    10.1016/j.ajhg.2013.03.016
  38. Gimenez-Maitre, A.; Le Henaff, C.; Norez, C.; Guillaume, C.; Ravoninjatovo, B.; Laurent-Maquin, D.; Becq, F.; Jacquot, J.. "Deficit of osteoprotegerin release by osteoblasts from a patient with cystic fibrosis". European Respiratory Journal 39 3 (2012): 780-781. http://www.scopus.com/inward/record.url?eid=2-s2.0-84860230604&partnerID=MN8TOARS.
    10.1183/09031936.00104111
  39. El-Seedy, A.; Girodon, E.; Norez, C.; Pajaud, J.; Pasquet, M.-C.; de Becdelièvre, A.; Bienvenu, T.; et al. "CFTR mutation combinations producing frequent complex alleles with different clinical and functional outcomes". Human Mutation 33 11 (2012): 1557-1565. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867466489&partnerID=MN8TOARS.
    10.1002/humu.22129
  40. Rode, B.; Dirami, T.; Bakouh, N.; Rizk-rabin, M.; Norez, C.; Lhuillier, P.; Lorès, P.; et al. "The testis anion transporter TAT1 (SLC26A8) physically and functionally interacts with the cystic fibrosis transmembrane conductance regulator channel: A potential role during sperm capacitation". Human Molecular Genetics 21 6 (2012): 1287-1298. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857664582&partnerID=MN8TOARS.
    10.1093/hmg/ddr558
  41. Becq, F.; Mall, M.A.; Sheppard, D.N.; Conese, M.; Zegarra-Moran, O.. "Pharmacological therapy for cystic fibrosis: From bench to bedside". Journal of Cystic Fibrosis 10 SUPPL. 2 (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-79958104493&partnerID=MN8TOARS.
    10.1016/S1569-1993(11)60018-0
  42. Cruz, F.P.D.; Newberry, S.; Jenkinson, S.F.; Wormald, M.R.; Butters, T.D.; Alonzi, D.S.; Nakagawa, S.; et al. "4-C-Me-DAB and 4-C-Me-LAB - Enantiomeric alkyl-branched pyrrolidine iminosugars - Are specific and potent a-glucosidase inhibitors; Acetone as the sole protecting group". Tetrahedron Letters 52 2 (2011): 219-223. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650022762&partnerID=MN8TOARS.
    10.1016/j.tetlet.2010.10.173
  43. Ardes-Guisot, N.; Alonzi, D.S.; Reinkensmeier, G.; Butters, T.D.; Norez, C.; Becq, F.; Shimada, Y.; et al. "Selection of the biological activity of DNJ neoglycoconjugates through click length variation of the side chain". Organic and Biomolecular Chemistry 9 15 (2011): 5373-5388. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960343811&partnerID=MN8TOARS.
    10.1039/c1ob05119a
  44. Renard, B.-L.; Boucherle, B.; Maurin, B.; Molina, M.-C.; Norez, C.; Becq, F.; Décout, J.-L.. "An expeditious access to 5-pyrimidinol derivatives from cyclic methylglyoxal diadducts, formation of argpyrimidines under physiological conditions and discovery of new CFTR inhibitors". European Journal of Medicinal Chemistry 46 5 (2011): 1935-1941. http://www.scopus.com/inward/record.url?eid=2-s2.0-79953167833&partnerID=MN8TOARS.
    10.1016/j.ejmech.2011.02.037
  45. Dannhoffer, L.; Billet, A.; Jollivet, M.; Melin-Heschel, P.; Faveau, C.; Becq, F.. "Stimulation of wild-type, F508del-and G551D-CFTR chloride channels by non-toxic modified pyrrolo[2,3-b]pyrazine derivatives". Frontiers in Pharmacology AUG (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-84865973907&partnerID=MN8TOARS.
    10.3389/fphar.2011.00048
  46. Ko, S.B.H.; Yamamoto, A.; Azuma, S.; Song, H.; Kamimura, K.; Nakakuki, M.; Gray, M.A.; et al. "Effects of CFTR gene silencing by siRNA or the luminal application of a CFTR activator on fluid secretion from guinea-pig pancreatic duct cells". Biochemical and Biophysical Research Communications 410 4 (2011): 904-909. http://www.scopus.com/inward/record.url?eid=2-s2.0-79960292093&partnerID=MN8TOARS.
    10.1016/j.bbrc.2011.06.093
  47. Ouedraogo, M.; Ruiz, M.; Vardelle, E.; Carreyre, H.; Coustard, J.M.; Potreau, D.; Sawadogo, L.L.; et al. "From the vasodilator and hypotensive effects of an extract fraction from Agelanthus dodoneifolius (DC) Danser (Loranthaceae) to the active compound dodoneine". Journal of Ethnopharmacology 133 2 (2011): 345-352. http://www.scopus.com/inward/record.url?eid=2-s2.0-78651399825&partnerID=MN8TOARS.
    10.1016/j.jep.2010.10.002
  48. Fresquet, F.; Clement, R.; Norez, C.; Sterlin, A.; Melin, P.; Becq, F.; Kitzis, A.; Thoreau, V.; Bilan, F.. "Orphan missense mutations in the cystic fibrosis transmembrane conductance regulator: A three-step biological approach to establishing a correlation between genotype and phenotype". Journal of Molecular Diagnostics 13 5 (2011): 520-527. http://www.scopus.com/inward/record.url?eid=2-s2.0-82755191694&partnerID=MN8TOARS.
    10.1016/j.jmoldx.2011.05.004
  49. Antigny, F.; Norez, C.; Becq, F.; Vandebrouck, C.. "CFTR and Ca2+ signaling in cystic fibrosis". Frontiers in Pharmacology OCT (2011): http://www.scopus.com/inward/record.url?eid=2-s2.0-84865973079&partnerID=MN8TOARS.
    10.3389/fphar.2011.00067
  50. Becq, F.. "CFTR channels and adenosine triphosphate release: The impossible rendez-vous revisited in skeletal muscle". Journal of Physiology 588 23 (2010): 4605-4606. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649717927&partnerID=MN8TOARS.
    10.1113/jphysiol.2010.200113
  51. Bertrand, J.; Boucherle, B.; Billet, A.; Melin-Heschel, P.; Dannhoffer, L.; Vandebrouck, C.; Jayle, C.; et al. "Identification of a novel water-soluble activator of wild-type and F508del CFTR: GPact-11a". European Respiratory Journal 36 2 (2010): 311-322. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955647867&partnerID=MN8TOARS.
    10.1183/09031936.00122509
  52. Antigny, F.; Norez, C.; Dannhoffer, L.; Bertrand, J.; Raveau, D.; Corbi, P.; Jayle, C.; Becq, F.; Vandebrouck, C.. "Transient receptor potential canonical channel 6 links Ca2+ mishandling to cystic fibrosis transmembrane conductance regulator channel dysfunction in cystic fibrosis". American Journal of Respiratory Cell and Molecular Biology 44 1 (2010): 83-90. http://www.scopus.com/inward/record.url?eid=2-s2.0-78650675175&partnerID=MN8TOARS.
    10.1165/rcmb.2009-0347OC
  53. Best, D.; Jenkinson, S.F.; Saville, A.W.; Alonzi, D.S.; Wormald, M.R.; Butters, T.D.; Norez, C.; et al. "Cystic fibrosis and diabetes: IsoLAB and isoDAB, enantiomeric carbon-branched pyrrolidine iminosugars". Tetrahedron Letters 51 32 (2010): 4170-4174. http://www.scopus.com/inward/record.url?eid=2-s2.0-77955303835&partnerID=MN8TOARS.
    10.1016/j.tetlet.2010.05.131
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