???global.info.a_carregar???
Identificação

Identificação pessoal

Nome completo
Maria de Jesus Almeida Rainha Perry da Câmara Saldanha Rocha

Identificadores de autor

Ciência ID
A516-1A46-D715
Produções

Publicações

Artigo em revista
  1. Margarida Granada; Eduarda Mendes; Maria Jesus Perry; Maria João Penetra; Maria Manuela Gaspar; Jacinta O. Pinho; Sofia Serra; Catarina Teixeira António; Ana Paula Francisco. "Sulfur Analogues of Tyrosine in the Development of Triazene Hybrid Compounds: A New Strategy against Melanoma". ACS Medicinal Chemistry Letters (2021): https://doi.org/10.1021/acsmedchemlett.1c00252.
    10.1021/acsmedchemlett.1c00252
  2. "Discovery of a Necroptosis Inhibitor Improving Dopaminergic Neuronal Loss after MPTP Exposure in Mice". International Journal of Molecular Sciences 22 10 (2021): 5289-5289. http://dx.doi.org/10.3390/ijms22105289.
    10.3390/ijms22105289
  3. Carrola, Joana; Duarte, Noélia; Florindo, Pedro; Henriques, Sara; da Silva, Gustavo; Bijlsma, Lubertus; Moreira, Rui; et al. "Metabolism of N-ethylhexedrone and buphedrone: An in vivo study in mice using HPLC-MS/MS". Journal of Chromatography B 1159 (2020): 122340. http://dx.doi.org/10.1016/j.jchromb.2020.122340.
    Publicado • 10.1016/j.jchromb.2020.122340
  4. Francisco, Ana P.; Mendes, Eduarda; Santos, Ana R.; Perry, Maria J.. "Anticancer Triazenes: from Bioprecursors to Hybrid Molecules". Current Pharmaceutical Design 25 14 (2019): 1623-1642. http://dx.doi.org/10.2174/1381612825666190617155749.
    Publicado • 10.2174/1381612825666190617155749
  5. Cláudia Braga; Ana R. Vaz; M. Conceição Oliveira; M. Matilde Marques; Rui Moreira; Dora Brites; Maria J. Perry. "Targeting gliomas with triazene-based hybrids: Structure-activity relationship, mechanistic study and stability". European Journal of Medicinal Chemistry 172 (2019): 16-25. https://doi.org/10.1016/j.ejmech.2019.03.048.
    10.1016/j.ejmech.2019.03.048
  6. Capela, R.; Magalhães, J.; Miranda, D.; Machado, M.; Sanches-Vaz, M.; Albuquerque, I.S.; Sharma, M.; et al. "Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability". European Journal of Medicinal Chemistry 149 (2018): 69-78. http://www.scopus.com/inward/record.url?eid=2-s2.0-85042651839&partnerID=MN8TOARS.
    10.1016/j.ejmech.2018.02.048
  7. Sousa, A.; Santos, F.; Gaspar, M.M.; Calado, S.; Pereira, J.D.; Mendes, E.; Francisco, A.P.; Perry, M.J.. "The selective cytotoxicity of new triazene compounds to human melanoma cells". Bioorganic and Medicinal Chemistry 25 15 (2017): 3900-3910. http://www.scopus.com/inward/record.url?eid=2-s2.0-85020296185&partnerID=MN8TOARS.
    10.1016/j.bmc.2017.04.049
  8. Pinheiro, R.; Braga, C.; Santos, G.; Bronze, M.R.; Perry, M.J.; Moreira, R.; Brites, D.; Falcão, A.S.. "Targeting Gliomas: Can a New Alkylating Hybrid Compound Make a Difference?". ACS Chemical Neuroscience 8 1 (2017): 50-59. http://www.scopus.com/inward/record.url?eid=2-s2.0-85013797326&partnerID=MN8TOARS.
    10.1021/acschemneuro.6b00169
  9. Perry, MJ. "Nanoformulations of a Triazene Analogue with Specific Affinity to Human Melanoma.". J Nanosci Adv Tech, 1 (4) pp 1-9 (2016):
    10.24218/jnat.2016.16.
  10. Rodrigues, C.A.B.; Frade, R.F.M.; Albuquerque, I.S.; Perry, M.J.; Gut, J.; Machado, M.; Rosenthal, P.J.; et al. "Targeting the erythrocytic and liver stages of malaria parasites with s-triazine-based hybrids". ChemMedChem 10 5 (2015): 883-890. http://www.scopus.com/inward/record.url?eid=2-s2.0-84928476505&partnerID=MN8TOARS.
    10.1002/cmdc.201500011
  11. Pereira, N.A.L.; Monteiro, Â.; Machado, M.; Gut, J.; Molins, E.; Perry, M.J.; Dourado, J.; et al. "Enantiopure Indolizinoindolones with in vitro Activity against Blood- and Liver-Stage Malaria Parasites". ChemMedChem 10 12 (2015): 2080-2089. http://www.scopus.com/inward/record.url?eid=2-s2.0-84951573479&partnerID=MN8TOARS.
    10.1002/cmdc.201500429
  12. Oliveira, R.; Miranda, D.; Magalhães, J.; Capela, R.; Perry, M.J.; O'Neill, P.M.; Moreira, R.; Lopes, F.. "From hybrid compounds to targeted drug delivery in antimalarial therapy". Bioorganic and Medicinal Chemistry 23 16 (2015): 5120-5130. http://www.scopus.com/inward/record.url?eid=2-s2.0-84938951204&partnerID=MN8TOARS.
    10.1016/j.bmc.2015.04.017
  13. Perry, MJ. "Design and discovery of mushroom tyrosinase inhibitors and their therapeutic applications.". Expert Opinion Drug Discovery, 2014. (5) 533-54. (2014):
    10.1517/17460441.2014.907789
  14. Blaszczak-Swiatkiewicz, K.; Almeida, D.C.; De Jesus Perry, M.; Mikiciuk-Olasik, E.. "Synthesis, anticancer activity and UPLC analysis of the stability of some New Benzimidazole-4,7-dione derivatives". Molecules 19 1 (2014): 400-413. http://www.scopus.com/inward/record.url?eid=2-s2.0-84893065343&partnerID=MN8TOARS.
    10.3390/molecules19010400
  15. Monteiro, A.S.; Almeida, J.; Cabral, G.; Severino, P.; Videira, P.A.; Sousa, A.; Nunes, R.; et al. "Synthesis and evaluation of N-acylamino acids derivatives of triazenes. Activation by tyrosinase in human melanoma cell lines". European Journal of Medicinal Chemistry 70 (2013): 1-9. http://www.scopus.com/inward/record.url?eid=2-s2.0-84885368654&partnerID=MN8TOARS.
    10.1016/j.ejmech.2013.09.040
  16. Carmo Carreiras, M.; Mendes, E.; Jesus Perry, M.; Francisco, A.P.; Marco-Contelles, J.. "The multifactorial nature of Alzheimer's disease for developing potential therapeutics". Current Topics in Medicinal Chemistry 13 15 (2013): 1745-1770. http://www.scopus.com/inward/record.url?eid=2-s2.0-84887972850&partnerID=MN8TOARS.
  17. Capucha, V.; Mendes, E.; Francisco, A.P.; Perry, M.J.. "Development of triazene prodrugs for ADEPT strategy: New insights into drug delivery system based on carboxypeptidase G2 activation". Bioorganic and Medicinal Chemistry Letters 22 22 (2012): 6903-6908. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867847410&partnerID=MN8TOARS.
    10.1016/j.bmcl.2012.09.029
  18. Perry, M.d.J.; Carvalho, E.; Rosa, E.; Iley, J.. "Towards an efficient prodrug of the alkylating metabolite monomethyltriazene: Synthesis and stability of N-acylamino acid derivatives of triazenes". European Journal of Medicinal Chemistry 44 3 (2009): 1049-1056. http://www.scopus.com/inward/record.url?eid=2-s2.0-60549095830&partnerID=MN8TOARS.
    10.1016/j.ejmech.2008.06.022
  19. Perry, M.J.; Mendes, E.; Simplício, A.L.; Coelho, A.; Soares, R.V.; Iley, J.; Moreira, R.; Francisco, A.P.. "Dopamine- and tyramine-based derivatives of triazenes: Activation by tyrosinase and implications for prodrug design". European Journal of Medicinal Chemistry 44 8 (2009): 3228-3234. http://www.scopus.com/inward/record.url?eid=2-s2.0-67349149632&partnerID=MN8TOARS.
    10.1016/j.ejmech.2009.03.025
  20. Carvalho, E.; Iley, J.; Perry, M.D.J.; Rosa, E.. "Triazene drug metabolites. Part 16.1 Kinetics and mechanism of the hydrolysis of aminoacyltriazenes". Journal of the Chemical Society. Perkin Transactions 2 11 (1998): 2375-2380. http://www.scopus.com/inward/record.url?eid=2-s2.0-0342738340&partnerID=MN8TOARS.
    10.1039/a805704d
  21. Carvalho, E.; Iley, J.; De Jesus Perry, M.; Rosa, E.. "Triazene drug metabolites: Part 15. Synthesis and plasma hydrolysis of anticancer triazenes containing amino acid carriers". Pharmaceutical Research 15 6 (1998): 931-935. http://www.scopus.com/inward/record.url?eid=2-s2.0-0031750508&partnerID=MN8TOARS.
    10.1023/A:1011988918476
  22. Burgess, J.; De Perry, M.J.; Rosa, E.; Iley, J.. "The carbohydrate-catalysed hydrolysis of cephalosporins". Journal of the Chemical Society, Perkin Transactions 2 1 (1994): 97-101. http://www.scopus.com/inward/record.url?eid=2-s2.0-37049070891&partnerID=MN8TOARS.
Capítulo de livro
  1. Perry, MJ. "Adittion to carbonyl compounds other than aldol reaction, Knorr Pyrazole Synthesis of Edaravone". Reino Unido: Royal Society of Chemistry, 2017.
    Publicado
  2. Perry, MJ. "Epoxidations, Stereoselective Epoxidation of Cholesterol by m-Chloroperoxybenzoic acid". 754. Reino Unido: Royal Society of Chemistry, 2017.
    Publicado
  3. Perry, MJ. "Wittig type reactions, Preparation of Nitrostilbenes by the Wittig reaction". 623. Reino Unido: Royal Society of Chemistry, 2017.
    Publicado
Livro
  1. Perry, MJ. Heterocyclic Targets in Advanced Organic Synthesis. Índia. 2011.
  2. Perry, MJ. Anticancer Therapeutics. Reino Unido. 2008.
  3. Francisco, A.P.; Perry, M.D.J.; Moreira, R.; Mendes, E.. Alkylating Agents. 2008.
    10.1002/9780470697047.ch9