Peter Jordan (A01A-1F55-88DB)

Curriculum Vitae

Peter Jordan

I am a Biologist and graduated at the University of Bonn, Germany, in 1989, and obtained my PhD at the German Cancer Research Centre in Heidelberg. Following a post-doctoral research in Lisbon, I was recruited by the National Institute of Health Dr. Ricardo Jorge, in Lisbon, where I became an independent group leader in 1999. Since 2003, I am a staff Principal Researcher at Instituto Nacional de Saúde Doutor Ricardo Jorge, and my current bibliographic data are 80 international peer reviewed publications, an h-index of 31 with over 3321 citations (according to Researcher ID (G-9335-2012) metrics in January 2024), 8 concluded PhD thesis supervisions, and PI of over 20 research grants over the last 25 years. My main research interest is signal transduction pathways in colon cancer. A major focus is the analysis of signalling pathways in cultured colorectal cancer cells, in particular concerning the small GTPases RAC1 or RAC1B, and the WNK family of protein kinases. Key methodological approaches include the analysis of RNA and protein expression, protein kinase and GTPase activity assays, protein complex analysis, and confocal microscopy.

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Identificação

Identificação pessoal

Nome completo: Peter Jordan

Nomes de citação

Jordan, Peter

Identificadores de autor

Ciência ID: A01A-1F55-88DB
ORCID iD: 0000-0002-1425-9211

Telefones

Telefone

217519380 (Profissional)

Moradas

Avenida Padre Cruz, 1649-016, Lisboa, Lisboa, Portugal (Profissional)

Domínios de atuação

Ciências Naturais - Ciências Biológicas - Biologia Celular

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão	Peer-review
Línguas Germânicas (Outras) (Idioma materno)
Inglês	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)
Português	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)
Francês	Utilizador proficiente (C1)	Utilizador independente (B2)	Utilizador independente (B2)	Utilizador independente (B2)	Utilizador independente (B2)

Formação

	Grau	Classificação
2009/10/08 Concluído	Novel Signalling molecules involved in cancer and rare genetic diseases (Título de Habilitação de Coordenação Científica) Especialização em Human Genetics Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	aprovado
1990/03 - 1993/06 Concluído	Biology (Doktor (PhD)) Ruprecht Karls Universität Heidelberg HIP Zellbiologie, Alemanha "Identification of phosphoproteíns pp100 e pp120, ubiquitous substrates of an ecto-proteín knase " (TESE/DISSERTAÇÃO)	very good
1983/09 - 1989/09 Concluído	Biology (Master) Rheinische Friedrich Wilhelms Universität Bonn Fachgruppe Biologie, Alemanha "Extraction and Characterization of vanadium-dependent bromoperoxidases in the brown algae Laminaria digitata " (TESE/DISSERTAÇÃO)	suma cum laude

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2003/06 - Atual	Investigador principal (carreira) (Investigação)	Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
	Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
1999/10 - 2003/06	Investigador principal convidado (carreira) (Investigação)	Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
	Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
1996/10 - 1999/09	Investigador Contratado (Investigação)	Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
	Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
1993/09 - 1996/09	Pós-doutorado (Investigação)	Universidade de Lisboa Faculdade de Medicina, Portugal
	Universidade de Lisboa Faculdade de Medicina, Portugal
1990/03/01 - 1993/06/23	Investigador (Investigação)	Deutsches Krebsforschungszentrum, Alemanha
	Ruprecht Karls Universität Heidelberg Fakultät für Biowissenschaften, Alemanha
1989/10 - 1990/02	Investigador visitante (Investigação)	Heinrich Hertz Stiftung, Alemanha
	Station Biologique de Roscoff, França

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2014/04 - Atual	Professor Associado Convidado (Docente Universitário)	Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal
	Universidade de Lisboa Faculdade de Ciências, Portugal

Projetos

Projeto

	Designação	Financiadores
2022/05 - 2029/04	EU Partnership for the Assessment of Risks from Chemicals (PARC) PARC Investigador Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Em curso
2018/10/04 - 2022/10/03	Mecanismos Celulares e Moleculares de Toxicidade dos Nanomateriais Ingeridos PTDC/SAU-PUB/29481/2017 Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2018/10/04 - 2022/09	Microenvironmental effects on alternative splicing in malignant progression of colorectal tumor cells PTDC/BIA-MOL/28386/2017 Investigador Fundação para a Ciência e a Tecnologia, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2018/10 - 2022/09	Novel signaling pathways regulating cell surface retention of epithelial choride transport proteins PTDF/BIA-CEL/28408/2017 Investigador responsável Fundação para a Ciência e a Tecnologia, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2018/10/04 - 2021/10/03	Uma abordagem de toxicologia preditiva para a caracterização dos potenciais efeitos respiratórios de fibras de nanocelulose funcionalizadas num sistema de co-cultura PTDC/SAU-PUB/32587/2017 Universidade de Coimbra, Portugal RAIZ Instituto de Investigação da Floresta e Papel, Portugal Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal	Fundação para a Ciência e a Tecnologia Em curso
2019/01/01 - 2019/12/31	Instituto de Biosistemas & Ciências Integrativas UID/Multi/04046/2019 Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal Universidade do Minho, Portugal Universidade do Porto Faculdade de Ciências, Portugal Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal FCiênciasID Associação para a Investigação e Desenvolvimento de Ciências, Portugal Universidade de Lisboa Faculdade de Ciências, Portugal Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2016/01 - 2019/12	Perturbation of the intestinal barrier function in inflammatory blowel disease: tole of the Rac1b/cytokine axis 06/2013 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	universidade do Porto - grupo de estudo da doença inflamatória intestinal Em curso
2015/07 - 2018/05	Tumor cell plasticity through alternative splicing in response to a 3D pro-inflammatory microenvironment, cancro 2014 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Maratona da Saúde Concluído
2016/01 - 2017/12	Protein networks stabilizing CFTR at the plasma membrane cc6202-P0.b Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Universidade de Lisboa Instituto de Biossistemas e Ciências Integrativas Concluído
2012/01 - 2014/12	New insights into the regulation of insulin-sensitive glucose transporters by protein kinases 117236 Provided by PTCRIS: 117236 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2011/02 - 2014/04	Potential predictive biomarkers of anti-RTKs therapy response in gliomas: An in vitro and in vivo study Provided by PTCRIS: 114549 114549 Investigador Universidade do Minho, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2012/03/01 - 2013/08	A novel Rac1/PAK1/BCL-6 pathway to regulate gene expression: genome-wide screening for target genes info:eu-repo/grantAgreement/FCT/3599-PPCDT/119586/PT Investigador Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2012/03 - 2013/08	A novel signalling pathway possibly involved in renal salt handling and hypertension 119782 Provided by PTCRIS: 119782 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia, I.P.
2010/01/01 - 2012/02/29	Papel da proteína cinase WNK2 como gene supressor de gliomas malignos PTDC/SAU-OBD/100079/2008 Universidade do Minho, Portugal Fundação da Faculdade de Ciências da Universidade de Lisboa, Portugal Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2010/01 - 2012/02	Role of protein kinase WNK2 as a tumour suppressor gene in malignant gliomas 100079 Provided by PTCRIS: 100079 Investigador responsável	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2009/01 - 2011/12	Effects of inflammation on Rac1b, a novel therapeutic target in colorectal tumours 96495 Investigador responsável	Fundação Calouste Gulbenkian Concluído
2007/08/01 - 2010/11/30	Role of novel regulatory mechanisms in the loss of E-cadherin expression PTDC/SAU-GMG/72168/2006 Instituto Nacional de Saúde Doutor Ricardo Jorge, Portugal Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2007/08 - 2010/11	Papel de novos mechanismos regulatórios na perda de expressão da caderina-E 72168 Provided by PTCRIS: 72168 Investigador Universidade do Porto Instituto de Patologia e Imunologia Molecular, Portugal	Fundação para a Ciência e a Tecnologia, I.P.
2007/01 - 2009/12	Molecular pathways involved in Gordon syndrome, a familial hypertension disease 82304 Provided by PTCRIS: 82304 Investigador responsável	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2007/01 - 2008/11	Implications for tumor development of Rac1/Rac1b-modulated gene transcription 82401 Provided by PTCRIS: 82401 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2007/01 - 2008/07	Role of WNK protein kinases in endosomal traffic 82124 Provided by PTCRIS: 82124 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2006/01 - 2007/06	Molecular pathways involved in Gordon syndrome, a familial hypertension disease 56439 Provided by PTCRIS: 56439 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2005/08 - 2007/06	Implications for tumor development of Rac1/Rac1b-modulated gene transcription 57660 Provided by PTCRIS: 57660 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2005/08 - 2007/06	Role of WNK protein kinases in endosomal traffic Provided by PTCRIS: 56294 56294 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia, I.P.
2003/11/01 - 2006/11/15	Regulation of alternative splicing of the small GTPase Rac1 info:eu-repo/grantAgreement/FCT/POCI/47546/PT Investigador responsável	Fundação para a Ciência e a Tecnologia Concluído
2005 - 2006	Microscopia confocal para a análise de doenças genéticas REEQ/791 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2004/04 - 2005/08	Alternative splicing confers novel signalling properties to Rac1, a role in colorectal tumour progression 04-008 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Association for International Cancer Research Concluído
2001/04 - 2004/04	Full-length cDNA cloning and biochemical characterization of a novel human protein kinase BME/33221/99 Investigador responsável	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2000/10 - 2004/03	A novel human splice variant of the small GTPase Rac1: characterization of its role in signalling and cell adhesion CBO/32976/99 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia Concluído
1999/03 - 2000/03	Characterization of a novel splice variant of the small GTPase Rac1, a member of the ras superfamily SAU/14136/98 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia Concluído
1997/11 - 2000/02	Cloning of novel serine/threonine protein kinases expressed in human colonic epithelial cells SAU/107/96 Investigador responsável Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal	Fundação para a Ciência e a Tecnologia, I.P. Concluído

Produções

Publicações

Artigo em conferência	Henriques, A. A.; Matos, P.; Jordan, P.. "Regulation of glucose transporters by protein kinases in cancer cells". Trabalho apresentado em ESMO 2017- European Society of Medical Oncology, Madrid, 2017. Publicado Goncalves, V.; Matos, P.; Henriques, A. A.; Pereira, J.; Jordan, P.. "Signal transduction pathways regulating alternative splicing of tumor-related RAC1b". Trabalho apresentado em ESMO 2017- European Society of Medical Oncology, Madrid, 2017. Publicado Barros, P.; Amaral, A. J.; Abrantes, L. B.; Oliveira, T.; Louro, H.; Silva, M. J.; Jordan, P.; Gama-Carvalho, M.; Matos, P.. "Stimulation of RAC1/PAK1 signalling upregulates DNA damage repair genes via the BCL6/STAT5-switch". Madrid, 2017. Publicado
Artigo em revista	Patrícia Barros; Ana M. Matos; Paulo Matos; Peter Jordan. "YES1 Kinase Mediates the Membrane Removal of Rescued F508del-CFTR in Airway Cells by Promoting MAPK Pathway Activation via SHC1". Biomolecules (2023): https://doi.org/10.3390/biom13060949. 10.3390/biom13060949 Dora Rolo; Ricardo Assunção; Célia Ventura; Paula Alvito; Lídia Gonçalves; Carla Martins; Ana Bettencourt; et al. "Adverse Outcome Pathways Associated with the Ingestion of Titanium Dioxide Nanoparticles—A Systematic Review". Nanomaterials (2022): https://doi.org/10.3390/nano12193275. 10.3390/nano12193275 Joana F. S. Pereira; Cláudia Bessa; Paulo Matos; Peter Jordan. "Pro-Inflammatory Cytokines Trigger the Overexpression of Tumour-Related Splice Variant RAC1B in Polarized Colorectal Cells". Cancers 14 6 (2022): 1393-1393. https://doi.org/10.3390/cancers14061393. 10.3390/cancers14061393 Matos, Ana M.; Jordan, Peter; Matos, Paulo. "Treatment of Polarized Cystic Fibrosis Airway Cells With HGF Prevents VX-661-Rescued F508del-CFTR Destabilization Caused by Prolonged Co-exposure to VX-770". Frontiers in Molecular Biosciences 8 (2021): http://dx.doi.org/10.3389/fmolb.2021.812101. Acesso aberto • Publicado • 10.3389/fmolb.2021.812101 Alves, Ana Catarina; Azevedo, Sílvia; Benito-Vicente, Asier; Graça, Rafael; Galicia-Garcia, Unai; Barros, Patrícia; Jordan, Peter; Martin, Cesar; Bourbon, Mafalda. "LDLR variants functional characterization: Contribution to variant classification". Atherosclerosis 329 (2021): 14-21. http://dx.doi.org/10.1016/j.atherosclerosis.2021.06.001. Publicado • 10.1016/j.atherosclerosis.2021.06.001 Joana F. S. Pereira; Peter Jordan; Paulo Matos. "A Signaling View into the Inflammatory Tumor Microenvironment". Immuno (2021): https://doi.org/10.3390/immuno1020007. 10.3390/immuno1020007 Cláudia Bessa; Paulo Matos; Peter Jordan; Vânia Gonçalves. "Alternative Splicing: Expanding the Landscape of Cancer Biomarkers and Therapeutics". International Journal of Molecular Sciences 21 23 (2020): 9032-9032. https://doi.org/10.3390/ijms21239032. Acesso aberto • Publicado • 10.3390/ijms21239032 Ventura, Célia; Pereira, Joana F. S.; Matos, Paulo; Marques, Bárbara; Jordan, Peter; Sousa-Uva, António; Silva, Maria João. "Cytotoxicity and genotoxicity of MWCNT-7 and crocidolite: assessment in alveolar epithelial cells versus their coculture with monocyte-derived macrophages". Nanotoxicology (2020): 1-25. http://dx.doi.org/10.1080/17435390.2019.1695975. 10.1080/17435390.2019.1695975 Ana Laura Vieira Alves; Angela Margarida Costa; Martinho O; Da Silva, V.D.; Peter Jordan; viviane silva; Reis RM. "WNK2 Inhibits Autophagic Flux in Human Glioblastoma Cell Line". Cells (2020): https://www.mdpi.com/2073-4409/9/2/485. 10.3390/cells9020485 Cláudia Almeida Loureiro; Francisco R. Pinto; Patrícia Barros; Paulo Matos; Peter Jordan. "A SYK/SHC1 pathway regulates the amount of CFTR in the plasma membrane". Cellular and Molecular Life Sciences (2020): https://doi.org/10.1007/s00018-020-03448-4. 10.1007/s00018-020-03448-4 Henriques, Andreia F.A.; Matos, Paulo; Carvalho, Ana Sofia; Azkargorta, Mikel; Elortza, Felix; Matthiesen, Rune; Jordan, Peter. "WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1". Archives of Biochemistry and Biophysics 679 (2020): 108223. http://dx.doi.org/10.1016/j.abb.2019.108223. No prelo • 10.1016/j.abb.2019.108223 Jordan, Peter; Gonçalves, Vânia; Matos, Paulo; Henriques, Andreia A. "Ibuprofen disrupts a WNK1/GSK3ß/SRPK1 protein complex required for expression of tumor-related splice variant RAC1B in colorectal cells". Oncotarget 11 (2020): 4421-4437. Publicado • 10.18632/oncotarget.27816 Jordan, Peter. "Tyrosine phosphorylation modulates cell surface expression of chloride cotransporters NKCC2 and KCC3". Archives of Biochemistry and Biophysics (2019): http://dx.doi.org/10.1016/j.abb.2019.05.022. Publicado • 10.1016/j.abb.2019.05.022 Jordan, Peter. "Network Biology Identifies Novel Regulators of CFTR Trafficking and Membrane Stability". Frontiers in Pharmacology (2019): http://dx.doi.org/10.3389/fphar.2019.00619. Publicado • 10.3389/fphar.2019.00619 Jordan, Peter; Gonçalves, Vânia; Matos, Paulo. "A new twist to Ibuprofen: alternative action in alternative splicing.". European Medical Journal 4 2 (2019): 64-71. https://www.emjreviews.com/oncology/article/a-new-twist-to-ibuprofen-alternative-action-in-alternative-splicing/. Publicado Larissa Kotelevets; Francine Walker; Godefroy Mamadou; Thérèse Lehy; Peter Jordan; Eric Chastre. "The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression". Oncogene (2018): https://doi.org/10.1038/s41388-018-0389-7. 10.1038/s41388-018-0389-7 Goncalves, Vania; Pereira, Joana F S; Jordan, Peter. "Signaling Pathways Driving Aberrant Splicing in Cancer Cells.". Genes 9 1 (2018): http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=MEDLINE&KeyUT=MEDLINE:29286307&KeyUID=MEDLINE:29286307. 10.3390/genes9010009 Matos, A. M.; Gomes-Duarte, A.; Faria, M.; Barros, P.; Jordan, P.; Amaral, M. D.; Matos, P.; et al. "Prolonged co-treatment with HGF sustains epithelial integrity and improves pharmacological rescue of Phe508del-CFTR". Sci Rep 8 1 (2018): 13026-13026. https://www.ncbi.nlm.nih.gov/pubmed/30158635. 10.1038/s41598-018-31514-2 Joana F. S. Pereira; Nikhil T. Awatade; Cláudia A. Loureiro; Paulo Matos; Margarida D. Amaral; Peter Jordan. "The third dimension: new developments in cell culture models for colorectal research". Cellular and Molecular Life Sciences (2016): http://dx.doi.org/10.1007/s00018-016-2258-2. 10.1007/s00018-016-2258-2 Matos P; Gonçalves V; Jordan P. "Targeting the serrated pathway of colorectal cancer with mutation in BRAF.". Biochim BioPhys Acta -Rev Cancer 1866, (2016): 51-56. http://europepmc.org/abstract/med/27345584. Publicado • 10.1016/j.bbcan.2016.06.003 Farinha CM; Swiatecka-Urban A; Brautigan DL; Jordan P. "Regulatory Crosstalk by Protein Kinases on CFTR Trafficking and Activity.". Front Chem 4:1 (2016): http://europepmc.org/abstract/med/26835446. Publicado • 10.3389/fchem.2016.00001 Jordan, Peter. "Expression of tumor-related Rac1b antagonizes B-Raf-induced senescence in colorectal cells". Cancer Letters (2015): 10.1016/j.canlet.2015.08.027 Matos L; Gonçalves V; Pinto E; Laranjeira F; Prata MJ; Jordan P; Desviat LR; Pérez B; Alves S. "Functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II.". Biochim Biophys Acta 1852 (2015): 2717-2721. http://europepmc.org/abstract/med/26407519. Publicado • 10.1016/j.bbadis.2015.09.011 Costa AM; Pinto F; Martinho O; Oliveira MJ; Jordan P; Reis RM. "Silencing of the tumor suppressor gene WNK2 is associated with upregulation of MMP2 and JNK in gliomas.". Oncotarget 6 (2015): 1422-1434. http://europepmc.org/abstract/med/25596741. Vânia Gonçalves; Peter Jordan. "Posttranscriptional Regulation of Splicing Factor SRSF1 and Its Role in Cancer Cell Biology". BioMed Research International 2015 (2015): 1-10. http://dx.doi.org/10.1155/2015/287048. 10.1155/2015/287048 Claudia Ghigna; Luca Cartegni; Peter Jordan; Maria Paola Paronetto. "Posttranscriptional Regulation and RNA Binding Proteins in Cancer Biology". BioMed Research International 2015 (2015): 1-2. http://dx.doi.org/10.1155/2015/897821. Publicado • 10.1155/2015/897821 • Editor Matos P; Jordan P. "Beyond COX-inhibition: 'side-effects' of ibuprofen on neoplastic development and progression.". Curr Pharm Design 21 (2015): 2978-2982. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000356081900008&KeyUID=WOS:000356081900008. Publicado • 10.2174/1381612821666150514104608 Matos, Liliana; Goncalves, Vania; Pinto, Eugenia; Laranjeira, Francisco; Prata, Maria Joao; Jordan, Peter; Desviat, Lourdes R; Perez, Belen; Alves, Sandra. "Data in support of a functional analysis of splicing mutations in the IDS gene and the use of antisense oligonucleotides to exploit an alternative therapy for MPS II.". Data in brief 5 (2015): 810-7. https://pubmed.ncbi.nlm.nih.gov/26693516/. 10.1016/j.dib.2015.10.011 Peter Jordan. "Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells". RNA (2014): http://www.rnajournal.org/cgi/pmidlookup?view=long&pmid=24550521. 10.1261/rna.041376.113 Matos L; Canals I; Dridi L; Choi Y; Prata MJ; Jordan P; Desviat LR; et al. "Therapeutic strategies based on modified U1 snRNAs and chaperones for Sanfilippo C splicing mutations.". Orphanet J Rare Dis 9 (2014): 180. http://europepmc.org/abstract/med/25491247. Publicado • 10.1186/s13023-014-0180-y Moniz, S.; Martinho, O.; Pinto, F.; Sousa, B.; Loureiro, C.; Oliveira, M.J.; Moita, L.F.; et al. "Loss of WNK2 expression by promoter gene methylation occurs in adult gliomas and triggers Rac1-mediated tumour cell invasiveness". Human Molecular Genetics 22 1 (2013): 84-95. http://www.scopus.com/inward/record.url?eid=2-s2.0-84871200220&partnerID=MN8TOARS. Publicado • 10.1093/hmg/dds405 Matos, P.; Kotelevets, L.; Gonçalves, V.; Henriques, A.; Zerbib, P.; Moyer, M.P.; Chastre, E.; Jordan, P.. "Ibuprofen inhibits colitis-induced overexpression of tumor- related Rac1b". Neoplasia (United States) 15 1 (2013): 102-111. http://www.scopus.com/inward/record.url?eid=2-s2.0-84873020742&partnerID=MN8TOARS. 10.1593/neo.121890 Vieira, L.; Vaz, A.; Matos, P.; Ambrósio, A.P.; Nogueira, M.; Marques, B.; Pereira, A.M.; Jordan, P.; da Silva, M.G.. "Three-way translocation (X;20;16)(p11;q13;q23) in essential thrombocythemia implicates NFATC2 in dysregulation of CSF2 expression and megakaryocyte proliferation". Genes Chromosomes and Cancer 51 12 (2012): 1093-1108. http://www.scopus.com/inward/record.url?eid=2-s2.0-84867233450&partnerID=MN8TOARS. 10.1002/gcc.21994 Pinheiro, H.; Carvalho, J.; Oliveira, P.; Ferreira, D.; Pinto, M.T.; Osoquot;rio, H.; Licastro, D.; et al. "Transcription initiation arising from E-cadherin/CDH1 intron2: A novel protein isoform that increases gastric cancer cell invasion and angiogenesis". Human Molecular Genetics 21 19 (2012): 4253-4269. http://www.scopus.com/inward/record.url?eid=2-s2.0-84866408689&partnerID=MN8TOARS. 10.1093/hmg/dds248 Barros, P.; Lam, E.W.-F.; Jordan, P.; Matos, P.. "Rac1 signalling modulates a STAT5/BCL-6 transcriptional switch on cell-cycle-associated target gene promoters". Nucleic Acids Research 40 16 (2012): 7776-7787. http://www.scopus.com/inward/record.url?eid=2-s2.0-84870572352&partnerID=MN8TOARS. Publicado • 10.1093/nar/gks571 Mendes, A.I.; Mascarenhas, M.R.; Matos, S.; Sousa, I.; Ferreira, J.; Barbosa, A.P.; Bicho, M.; Jordan, P.. "A WNK4 gene variant relates to osteoporosis and not to hypertension in the Portuguese population". Molecular Genetics and Metabolism 102 4 (2011): 465-469. http://www.scopus.com/inward/record.url?eid=2-s2.0-79952623807&partnerID=MN8TOARS. 10.1016/j.ymgme.2010.12.010 Mendes, Ana Isabel; Matos, Paulo; Moniz, Sonia; Luz, Simao; Amaral, Margarida D.; Farinha, Carlos M.; Jordan, Peter. "Antagonistic Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Cell Surface Expression by Protein Kinases WNK4 and Spleen Tyrosine Kinase". Molecular and Cellular Biology 31 19 (2011): 4076-4086. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000294710100015&KeyUID=WOS:000294710100015. Publicado • 10.1128/mcb.05152-11 Luz, S.; Kongsupho, P.; Mendes, A.I.; Romeiras, F.; Sousa, M.; Schreiber, R.; Matos, P.; et al. "Contribution of casein kinase 2 and spleen tyrosine kinase to CFTR trafficking and protein kinase a-induced activity". Molecular and Cellular Biology 31 22 (2011): 4392-4404. http://www.scopus.com/inward/record.url?eid=2-s2.0-83255187903&partnerID=MN8TOARS. Publicado • 10.1128/MCB.05517-11 Luz, Simão; Kongsuphol, Patthara; Mendes, Ana Isabel; Romeiras, Francisco; Sousa, Marisa; Schreiber, Rainer; Matos, Paulo; et al. "The contribution of CK2 and spleen tyrosine kinase (SYK) to CFTR trafficking and PKA-induced activity". (2011): http://hdl.handle.net/10400.18/907. Moniz, S.; Jordan, P.. "Emerging roles for WNK kinases in cancer". Cellular and Molecular Life Sciences 67 8 (2010): 1265-1276. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950604823&partnerID=MN8TOARS. 10.1007/s00018-010-0261-6 Dias, E.; Matos, P.; Pereira, P.; Batoréu, M.C.C.; Silva, M.J.; Jordan, P.. "Microcystin-LR activates the ERK1/2 kinases and stimulates the proliferation of the monkey kidney-derived cell line Vero-E6". Toxicology in Vitro 24 6 (2010): 1689-1695. http://www.scopus.com/inward/record.url?eid=2-s2.0-77956172500&partnerID=MN8TOARS. 10.1016/j.tiv.2010.05.018 Mendes, A.I.; Matos, P.; Moniz, S.; Jordan, P.. "Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex". Journal of Biological Chemistry 285 50 (2010): 39117-39126. http://www.scopus.com/inward/record.url?eid=2-s2.0-78649807481&partnerID=MN8TOARS. 10.1074/jbc.M110.159418 Velho, S.; Oliveira, C.; Paredes, J.; Sousa, S.; Leite, M.; Matos, P.; Milanezi, F.; et al. "Mixed lineage kinase 3 gene mutations in mismatch repair deficient gastrointestinal tumours". Human Molecular Genetics 19 4 (2010): 697-706. http://www.scopus.com/inward/record.url?eid=2-s2.0-77950353937&partnerID=MN8TOARS. 10.1093/hmg/ddp536 Barros, Patricia; Jordan, Peter; Matos, Paulo. "Rac1 Signaling Modulates BCL-6-Mediated Repression of Gene Transcription". Molecular and Cellular Biology 29 15 (2009): 4156-4166. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000267939400012&KeyUID=WOS:000267939400012. Publicado • 10.1128/mcb.01813-08 Dias, E.; Andrade, M.; Alverca, E.; Pereira, P.; Batoréu, M.C.C.; Jordan, P.; Silva, M.J.. "Comparative study of the cytotoxic effect of microcistin-LR and purified extracts from Microcystis aeruginosa on a kidney cell line". Toxicon 53 5 (2009): 487-495. http://www.scopus.com/inward/record.url?eid=2-s2.0-61449170919&partnerID=MN8TOARS. 10.1016/j.toxicon.2009.01.029 Alverca, E.; Andrade, M.; Dias, E.; Sam Bento, F.; Batoréu, M.C.C.; Jordan, P.; Silva, M.J.; Pereira, P.. "Morphological and ultrastructural effects of microcystin-LR from Microcystis aeruginosa extract on a kidney cell line". Toxicon 54 3 (2009): 283-294. http://www.scopus.com/inward/record.url?eid=2-s2.0-67649414226&partnerID=MN8TOARS. 10.1016/j.toxicon.2009.04.014 Gonçalves, V.; Matos, P.; Jordan, P.. "Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways". Human Molecular Genetics 18 19 (2009): 3696-3707. http://www.scopus.com/inward/record.url?eid=2-s2.0-70350782482&partnerID=MN8TOARS. 10.1093/hmg/ddp317 Gonçalves, V.; Theisen, P.; Antunes, O.; Medeira, A.; Ramos, J.S.; Jordan, P.; Isidro, G.. "A missense mutation in the APC tumor suppressor gene disrupts an ASF/SF2 splicing enhancer motif and causes pathogenic skipping of exon 14". Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 662 1-2 (2009): 33-36. http://www.scopus.com/inward/record.url?eid=2-s2.0-60749118005&partnerID=MN8TOARS. 10.1016/j.mrfmmm.2008.12.001 Seruca, R.; Velho, S.; Oliveira, C.; Leite, M.; Matos, P.; Jordan, P.. "Unmasking the role of KRAS and BRAF pathways in MSI colorectal tumors". Expert Rev Gastroenterol Hepatol 3 1 (2009): 5-9. http://www.ncbi.nlm.nih.gov/pubmed/19210107. 10.1586/17474124.3.1.5 [pii]10.1586/17474124.3.1.5 Matos, Paulo; Jordan, Peter; Matos, P.; Jordan, P.. "Increased Rac1b expression sustains colorectal tumor cell survival". Molecular Cancer Research 6 7 (2008): 1178-1184. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000257895900010&KeyUID=WOS:000257895900010. 10.1158/1541-7786.mcr-08-0008 Gonçalves, V.; Matos, P.; Jordan, P.. "The ß-catenin/TCF4 pathway modifies alternative splicing through modulation of SRp20 expression". RNA 14 12 (2008): 2538-2549. http://www.scopus.com/inward/record.url?eid=2-s2.0-57049129377&partnerID=MN8TOARS. 10.1261/rna.1253408 Moniz, S.; Matos, P.; Jordan, P.. "WNK2 modulates MEK1 activity through the Rho GTPase pathway". Cellular Signalling 20 10 (2008): 1762-1768. http://www.scopus.com/inward/record.url?eid=2-s2.0-49549097880&partnerID=MN8TOARS. 10.1016/j.cellsig.2008.06.002 Vieira, L.; Martinho, A.; Antunes, O.; Silva, E.; Ambrósio, A.P.; Geraldes, M.C.; Nascimento, R.; et al. "Combined molecular diagnosis of b-cell lymphomas with t(11;14)(q13;q32) or t(14;18)(q32;q21) using multiplex- and long distance inverse-polymerase chain reaction". Diagnostic Molecular Pathology 17 2 (2008): 73-81. http://www.scopus.com/inward/record.url?eid=2-s2.0-47049112999&partnerID=MN8TOARS. 10.1097/PDM.0b013e31814be9e0 Matos, P.; Oliveira, C.; Velho, S.; Gonçalves, V.; da Costa, L.T.; Moyer, M.P.; Seruca, R.; Jordan, P.. "B-RafV600E Cooperates With Alternative Spliced Rac1b to Sustain Colorectal Cancer Cell Survival". Gastroenterology 135 3 (2008): 899-906. http://www.scopus.com/inward/record.url?eid=2-s2.0-51249098983&partnerID=MN8TOARS. 10.1053/j.gastro.2008.05.052 Moniz, S.; Veríssimo, F.; Matos, P.; Brazão, R.; Silva, E.; Kotevelets, L.; Chastre, E.; Gespach, C.; Jordan, P.. "Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2". Oncogene 26 41 (2007): 6071-6081. http://www.scopus.com/inward/record.url?eid=2-s2.0-34548485789&partnerID=MN8TOARS. 10.1038/sj.onc.1210706 Veríssimo, F.; Silva, E.; Morris, J.D.; Pepperkok, R.; Jordan, P.. "Protein kinase WNK3 increases cell survival in a caspase-3-dependent pathway". Oncogene 25 30 (2006): 4172-4182. http://www.scopus.com/inward/record.url?eid=2-s2.0-33746058616&partnerID=MN8TOARS. 10.1038/sj.onc.1209449 Vieira, L.; Sousa, A.C.; Matos, P.; Marques, B.; Alaiz, H.; Ribeiro, M.J.; Braga, P.; Da Silva, M.G.; Jordan, P.. "Three-way translocation involves MLL, MLLT3, and a novel cell cycle control gene, FLJ10374, in the pathogenesis of acute myeloid leukemia with t(9;11;19)(p22;q23;p13.3)". Genes Chromosomes and Cancer 45 5 (2006): 455-469. http://www.scopus.com/inward/record.url?eid=2-s2.0-33645814404&partnerID=MN8TOARS. 10.1002/gcc.20311 Matos, P.; Jordan, P.. "Rac1, but not Rac1B, stimulates RelB-mediated gene transcription in colorectal cancer cells". Journal of Biological Chemistry 281 19 (2006): 13724-13732. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744965194&partnerID=MN8TOARS. 10.1074/jbc.M513243200 Matos, P.; Jordan, P.. "Expression of Rac1b stimulates NF-¿B-mediated cell survival and G1/S progression". Experimental Cell Research 305 2 (2005): 292-299. http://www.scopus.com/inward/record.url?eid=2-s2.0-16244378220&partnerID=MN8TOARS. 10.1016/j.yexcr.2004.12.029 Matos, P.; Collard, J.G.; Jordan, P.. "Tumor-related Alternatively Spliced Rac1b Is Not Regulated by Rho-GDP Dissociation Inhibitors and Exhibits Selective Downstream Signaling". Journal of Biological Chemistry 278 50 (2003): 50442-50448. http://www.scopus.com/inward/record.url?eid=2-s2.0-0347379871&partnerID=MN8TOARS. 10.1074/jbc.M308215200 Clarke, L.A.; Rebelo, C.S.; Gonçalves, J.; Boavida, M.G.; Jordan, P.. "PCR amplification introduces errors into mononucleotide and dinucleotide repeat sequences". Journal of Clinical Pathology - Molecular Pathology 54 5 (2001): 351-353. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034817160&partnerID=MN8TOARS. 10.1136/mp.54.5.351 Veríssimo, F.; Jordan, P.. "WNK kinases, a novel protein kinase subfamily in multi-cellular organisms". Oncogene 20 39 (2001): 5562-5569. http://www.scopus.com/inward/record.url?eid=2-s2.0-0035817725&partnerID=MN8TOARS. 10.1038/sj.onc.1204726 Matos, P.; Skaug, J.; Marques, B.; Beck, S.; Veríssimo, F.; Gespach, C.; Boavida, M.G.; Scherer, S.W.; Jordan, P.. "Small GTPase Rac1: Structure, localization, and expression of the human gene". Biochemical and Biophysical Research Communications 277 3 (2000): 741-751. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034597710&partnerID=MN8TOARS. 10.1006/bbrc.2000.3743 Clarke, L.A.; Jordan, P.; Boavida, M.G.. "Cell type specificity in alternative splicing of the human mismatch repair gene hMSH2". European Journal of Human Genetics 8 5 (2000): 347-352. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034078917&partnerID=MN8TOARS. 10.1038/sj.ejhg.5200472 Clarke, L. A.; Veiga, I.; Isidro, G.; Jordan, P.; Ramos, J. S.; Castedo, S.; Boavida, M. G.. "Pathological exon skipping in an HNPCC proband with MLHI splice acceptor site mutation". Genes Chromosomes & Cancer 29 4 (2000): 367-370. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000165063200014&KeyUID=WOS:000165063200014. 10.1002/1098-2264(2000)9999:9999<::aid-gcc1051>3.0.co;2-v Jordan, P.; Carmo-Fonseca, M.. "Molecular mechanisms involved in cisplatin cytotoxicity". Cellular and Molecular Life Sciences 57 8-9 (2000): 1229-1235. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000089074300009&KeyUID=WOS:000089074300009. 10.1007/pl00000762 Jordan, P.; Matos, P.; Veríssimo, F.. "Gene cloning at the computer screen: Possibilities and problems". Biochemical and Biophysical Research Communications 279 3 (2000): 741-743. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034731412&partnerID=MN8TOARS. 10.1006/bbrc.2000.3901 Jordan, P.; Brazao, R.; Boavida, M. G.; Gespach, C.; Chastre, E.. "Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors". Oncogene 18 48 (1999): 6835-6839. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000083792000028&KeyUID=WOS:000083792000028. 10.1038/sj.onc.1203233 Jordan, P.; Carmo-Fonseca, M.. "Cisplatin inhibits synthesis of ribosomal RNA in vivo". Nucleic Acids Research 26 12 (1998): 2831-2836. http://www.scopus.com/inward/record.url?eid=2-s2.0-0032526319&partnerID=MN8TOARS. 10.1093/nar/26.12.2831 Jordan, P.; Cunha, C.; Carmo-Fonseca, M.. "The cdk7-cyclin H-MAT1 complex associated with TFIIH is localized in coiled bodies". Molecular Biology of the Cell 8 7 (1997): 1207-1217. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030793104&partnerID=MN8TOARS. Jordan, P.; Mannervik, M.; Tora, L.; Carmo-Fonseca, M.. "In vivo evidence that TATA-binding protein/SL1 colocalizes with UBF and RNA polymerase I when rRNA synthesis is either active or inactive". Journal of Cell Biology 133 2 (1996): 225-234. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029914626&partnerID=MN8TOARS. 10.1083/jcb.133.2.225 Carmo-Fonseca, M.; Cunha, C.; Custódio, N.; Carvalho, C.; Jordan, P.; Ferreira, J.; Parreira, L.. "The topography of chromosomes and genes in the nucleus". Experimental Cell Research 229 2 (1996): 247-252. http://www.scopus.com/inward/record.url?eid=2-s2.0-0030589487&partnerID=MN8TOARS. 10.1006/excr.1996.0367 Jordan, P.; Kubler, D.. "Autoimmune diseases: Nuclear autoantigens can be found at the cell- surface". Molecular Biology Reports 22 1 (1996): 63-66. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029805584&partnerID=MN8TOARS. Carvalho, T.; Seeler, J.-S.; Ohman, K.; Jordan, P.; Pettersson, U.; Akusjarvi, G.; Carmo-Fonseca, M.; Dejean, A.. "Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix- associated PML bodies". Journal of Cell Biology 131 1 (1995): 45-56. http://www.scopus.com/inward/record.url?eid=2-s2.0-0029100611&partnerID=MN8TOARS. 10.1083/jcb.131.1.45 Jordan, P.; Heid, H.; Kinzel, V.; Kübler, D.. "Major cell surface-located protein substrates of an ecto-protein kinase are homologs of known nuclear proteins". Biochemistry 33 49 (1994): 14696-14706. http://www.scopus.com/inward/record.url?eid=2-s2.0-0028558474&partnerID=MN8TOARS. Schiess, K.; Kaszkin, M.; Jordan, P.; Seidler, L.; Kinzel, V.. "Mobilization of diacylglycerol in intact HeLa cells by exogenous phospholipase C from Cl. perfringens is accompanied by release of fatty acids including arachidonic acid". Biochimica et Biophysica Acta - Molecular Cell Research 1137 1 (1992): 82-94. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026672025&partnerID=MN8TOARS. 10.1016/0167-4889(92)90104-J Jordan, P.; Kubler, D.. "Ecto-protein kinase release differs from cleavage by phospholipases of a glycosyl-phosphatidylinositol membrane anchor". Biochemistry International 26 1 (1992): 97-104. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026583904&partnerID=MN8TOARS. Jordan, P.; Vilter, H.. "Extraction of proteins from material rich in anionic mucilages: Partition and fractionation of vanadate-dependent bromoperoxidases from the brown algae Laminaria digitata and L. Saccharina in aqueous polymer two-phase systems". Biochimica et Biophysica Acta - General Subjects 1073 1 (1991): 98-106. http://www.scopus.com/inward/record.url?eid=2-s2.0-0026079131&partnerID=MN8TOARS. 10.1016/0304-4165(91)90188-M Jordan, P.; Vilter, H.. "Native bromoperoxidases do not bind to nitrocellulose: Use of DEAE-cellulose as an alternative in blotting". Electrophoresis 11 8 (1990): 653-655. http://www.scopus.com/inward/record.url?eid=2-s2.0-0025125461&partnerID=MN8TOARS. 10.1002/elps.1150110814
Capítulo de livro	Matos, Paulo; Pereira, JFS; Jordan, Peter. "Targeting cancer by using nanoparticles to modulate RHO GTPase signaling". In Nanotoxicology in safety assessment of nanomaterials. Springer Nature, 2022. No prelo Jordan, Peter; Vânia Gonçalves; Sara Fernandes; Tânia Marques; Marcelo Pereira; Margarida Gama-Carvalho. "Networks of mRNA Processing and Alternative Splicing Regulation in Health and Disease". 2019. Publicado • 10.1007/978-3-030-19966-1_1 Jordan, Peter. "Colorectal Cancer Subtypes - The Current Portrait". In Targeted Therapy of Colorectal Cancer Subtypes, 1-6. Springer International Publishing, 2018. Publicado • 10.1007/978-3-030-02771-1_1 Matos, Paulo; Jordan, Peter. "Targeting Colon Cancers with Mutated BRAF and Microsatellite Instability". In Targeted Therapy of Colorectal Cancer Subtypes, 7-21. Springer International Publishing, 2018. Publicado • 10.1007/978-3-030-02771-1_2 Matos, Paulo; Gonçalves, Vânia; Jordan, Peter. "Therapeutic Approaches Targeting the Serrated Pathway of Colorectal Cancer Characterized by Mutation in the BRAF Gene and Overexpression of GTPase Rac1b". In Therapeutic Targets for Inflammation and Cancer, 233-255. WORLD SCIENTIFIC, 2017. Publicado • 10.1142/9789813148574_0011 Jordan, Peter; Vânia Gonçalves. "The deleterious effect of missense mutations on pre-mRNA splicing". In Advances in Genetics Research, 141-152. Nova Science Publisher, 2011. Publicado Jordan, Peter; Moniz, Sónia. "WNK kinase signalling in cancer biology". In Emerging Signaling Pathways in Tumor Biology, 43-71. kerala, Índia: Transworld Research Network,, 2010. Publicado Jordan, Peter; Gonçalves, Vânia; Matos, Paulo. "Alternative splicing changes regulation and signalling properties of the small GTPase Rac1". In Alternative Splicing and Cancer, 45-65. Kerala, Índia: Transworld Research Network, 2006. Publicado
Edição de livro	Jordan, Peter. Targeted Therapy of Colorectal Cancer Subtypes. Springer International Publishing. 2018. Publicado • 10.1007/978-3-030-02771-1 • Editor
Poster em conferência	Jordan, Peter. "More than 50 poster authored in the last 8 years". Trabalho apresentado em various national and international meetings, 2015.

Atividades

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2004 - Atual	9 PhD student theses concluded (Paulo Matos-2004, Fátima Veríssimo-2004, Sónia Moniz-2007, Ana Isabel Mendes-2008, Vânia Gonçalves- 2009, Patrícia Barros-2012, Cláudia Loureiro- 2019, Andreia Henriques- 2019; Joana Pereira- 2021) Orientador	Universidade de Lisboa Faculdade de Ciências, Portugal
2000 - Atual	10 MSc theses supervision: Raquel França Brazão, 2000; Carla Sofia Branquinho Rebelo, 2001; José António Almeida, 2002; Zita Carvalho, 2005; Patrícia Barros, 2007; Bruno Rother Moraes, 2010; Andreia Filipa Almeida Henriques, 2011; Cláudia Almeida Loureiro, 2012; Cláudia Alexandra da Silva Rodrigues, 2018; Telma Rosado, 2021. Coorientador	Universidade de Lisboa, Portugal

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2024	External opponent in over 25 PhD and 15 MSc defenses Arguente principal	national students (Doutoramento) Universidade de Lisboa Faculdade de Ciências, Portugal Universidade do Porto Faculdade de Medicina, Portugal

Arbitragem científica em revista

	Nome da revista (ISSN)	Editora
2000 - 2024	Regular reviewer of over 70 manuscripts for multiple international journals (including BBB, Cancers, Cell Chem Biol, CMLS, FASEB J, FEBS J, J Cell Science, Mol Cell Biol, Mol Cancer, NAR Cancer, Oncogene, PLoS One, RNA, Theranostics, TIBS)	various

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2023/02 - Atual	Scientific coordinator of a course unit on Oncobiology for Master's student	Mestrado em Bioquímica e Biomedicina (Mestrado)	Universidade de Lisboa Faculdade de Ciências, Portugal
2014/04 - Atual	sporadic oncobiologia class teaching	Bioquímica (Mestrado)	Universidade de Lisboa Faculdade de Ciências, Portugal

Membro de associação

	Nome da associação	Tipo de participação
2022/01/01 - 2024/12/31	Elected President of the Portuguese Society of Human Genetics	Executive President in 2023; Vice-president in 2022 and 2024

Membro de comissão

	Descrição da atividade Tipo de participação	Instituição / Organização
2017/06 - 2023/12	Elected President of the Scientific Council of the National Health Institute Dr. Ricardo Jorge Coordenador	Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal

Distinções

Título

2020	Re-election as President of the Scientific Council of my institution Instituto Nacional de Saúde Doutor Ricardo Jorge IP, Portugal

Outra distinção

2023	elected President of the Portuguese Society of Human Genetics Sociedade Portuguesa de Genética Humana, Portugal