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Vânia M. Moreira (VMM) holds a doctoral degree in Pharmaceutical Chemistry (2008) from the University of Coimbra, in Portugal. She is an Assistant Professor at the Faculty of Pharmacy of the University of Coimbra, since 2019. She is awarded with the "Title of Docent" (Dosentti) from the University of Helsinki, in Finland, since 2015. Prior to her relocation to Portugal in 2019, she was a post-doctoral researcher at the Faculty of Pharmacy, University of Coimbra (2009-2012), a post-doctoral reseacher at the Faculty of Pharmacy, University of Helsinki, Finland (2012-2015) and later a PI (2015-to date), and then a Lecturer in Medicinal Chemistry (2017-2020), at the Strathclyde Institute of Pharmacy and Biomedical Sciences (SIPBS), at the University of Strathclyde, Scotland, UK. She is a highly international researcher having worked & lived in Portugal, the USA, Italy , Finland and the UK. VMM is a Fellow of the Higher Education Academy (FHEA) since 2018, a professional recognition scheme for university lecturers with teaching practices well-aligned with the United Kingdom Professional Standards framework (UKPSF). She also holds a post-graduate certificate in knowledge exchange, from the University of Strathclyde, since 2019. Her research focuses on finding new therapies to target resistant infections by exploring the medicinal properties of small terpenoid compounds. She also investigates innovative surfaces based on polymers from nature, in search for more eco-friendly antimicrobial polymers that can replace those derived from fossil-fuels. VMM has attracted funding as leading project investigator (PI) and as project participant from international sources including Business Finland, the Academy of Finland, the Magnus Ehrnrooth Foundation, the Huonekalusäätiö, the Engineering and Physical Sciences Research Council (EPSRC, UK), Tenovus Scotland, the European Union (Seventh Framework Programme, FP7), the European networking COST action CM1307 (2016-2018), the Portuguese national funding agency for science, research and technology (FCT) and the University of Coimbra (INOVC+). She has authored/co-authored several peer-reviewed publications and is an inventor in patents. She supervises/has supervised post-doctoral researchers, doctoral and masters’ students. Her work was presented in international and national scientific meetings as oral and poster communications. She has been the examiner of doctoral and masters’ thesis and the external reviewer for grant applications of research institutions in Serbia, Slovenia, the UK, Finland and Denmark. In recognition of her research achievements, VMM was highlighted by the European Federation of Medicinal Chemistry (EFMC), as one of the "New talents Europe 2016". Other international awards and distinctions, won competitively throughout her career incude: the Chancellor’s Research Fellowship, University of Strathclyde, UK (Set 2017), selection for the ERC StG 2015 Interview step (appl. no. 678342, 1 499 714EUR), having her doctoral work selected by Atomium Culture EU news highlights (2012), receiving the highest grade in her doctoral dissertation defense at the University of Coimbra (2008) and receiveing the "Best student of Pharmacy in Portugal" award, in 2013 (Prémio Sociedade Farmacêutica Lusitana). VMM is a Committee Member for the Group for the Promotion of Pharmaceutical chemistry in Academia (GP2A) since 2019, a member-led network of academic medicinal chemists in Europe, where she organises several international conferences and promotes student exchange programmes. She serves(ed) as a member scientific advisory and session chair of several international meetings. She is a regular reviewer for several journals in the field of organic & medicinal chemsitry.
Identificação

Identificação pessoal

Nome completo
Vania M Moreira

Nomes de citação

  • Moreira, Vania

Identificadores de autor

Ciência ID
981F-DD99-F0B7
ORCID iD
0000-0001-6169-5035

Endereços de correio eletrónico

  • vmoreira@ff.uc.pt (Profissional)

Moradas

  • Pólo das Ciências da Saúde, Azinhaga de Santa Comba, 3000-548, Coimbra, Coimbra, Portugal (Profissional)

Domínios de atuação

  • Ciências Médicas e da Saúde - Ciências da Saúde

Idiomas

Idioma Conversação Leitura Escrita Compreensão Peer-review
Inglês Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2) Utilizador proficiente (C2)
Português (Idioma materno)
Formação
Grau Classificação
2019/09
Concluído
Post-Graduate Certificate in Knowledge Exchange (Pós-Graduação)
University of Strathclyde, Reino Unido
2018/10
Concluído
Fellow of the Higher Education Academy (FHEA) (Outros)
Higher Education Academy, Reino Unido
2015/05/12
Concluído
Title of Docent (Dosentti) (Outros)
Helsingin Yliopisto, Finlândia
2008/06/05
Concluído
Farmácia (Doutoramento)
Universidade de Coimbra, Portugal
Passed with Distinction and Honours
2003/04/29
Concluído
Ciências Farmacêuticas (Licenciatura)
Universidade de Coimbra, Portugal
Percurso profissional

Ciência

Categoria Profissional
Instituição de acolhimento
Empregador
2018/11 - Atual Investigador visitante (Investigação) Helsingin Yliopisto, Finlândia
2020/09 - 2022/04 Investigador visitante (Investigação) University of Strathclyde, Reino Unido
2015/05 - 2018/10 Investigador principal (carreira) (Investigação) Helsingin Yliopisto, Finlândia
2017/05 - 2017/08 Investigador visitante (Investigação) University of Strathclyde, Reino Unido
2012/05 - 2015/05 Pós-doutorado (Investigação) Helsingin Yliopisto, Finlândia
2009/04 - 2012/04 Pós-doutorado (Investigação) Universidade de Coimbra, Portugal
2011/05 - 2011/10 Investigador visitante (Investigação) Università degli Studi di Ferrara, Itália
2006/02 - 2007/03 Estagiário de Investigação (Investigação) University of Maryland School of Medicine, Estados Unidos

Docência no Ensino Superior

Categoria Profissional
Instituição de acolhimento
Empregador
2019/09/15 - Atual Professor Auxiliar (Docente Universitário) Universidade de Coimbra, Portugal
Universidade de Coimbra Faculdade de Farmácia, Portugal
2017/09 - 2020/08 Leitor (Docente Universitário) University of Strathclyde, Reino Unido
Strathclyde Institute of Pharmacy and Biomedical Sciences, Reino Unido
2008/10 - 2012/02 Professor Auxiliar (Docente Universitário) Universidade Lusófona de Humanidades e Tecnologias, Portugal
2008/10 - 2009/02 Professor Auxiliar (Docente Universitário) Escola Superior de Saúde Ribeiro Sanches, Portugal

Outros

Categoria Profissional
Instituição de acolhimento
Empregador
2016/06 - 2017/05 Maternity leave Helsingin Yliopisto, Finlândia
Projetos

Bolsa

Designação Financiadores
2012/05 - 2013/04 Design, synthesis and biological evaluation of new diterpenoids with potential for the treatment of cancer
ME2012n44
Investigador responsável
Magnus Ehrnroothin Säätiö
2009/04 - 2012/03 PREPARAÇÃO E AVALIAÇÃO PRÉ-CLÍNICA DE NOVOS COMPOSTOS BORADOS COMO POTENCIAIS AGENTES ANTITUMORAIS
Provided by PTCRIS: SFRH/BPD/45037/2008
Bolseiro de Pós-Doutoramento
Fundação para a Ciência e a Tecnologia
2003/12 - 2007/11 NOVOS ESTERÓIDES INIBIDORES DA BIOSSÍNTESE DE ANDROGÉNEOS
Provided by PTCRIS: SFRH/BD/12508/2003
Bolseiro de Doutoramento
Fundação para a Ciência e a Tecnologia

Projeto

Designação Financiadores
2021/01/01 - 2025/12/31 Center for Innovative Biomedicine and Biotechnology - Associate Laboratory
LA/P/0058/2020
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Em curso
2022/10 - 2023/09 Polímeros naturais biodegradáveis para filmes antimicrobianos e biocompatíveis (PHAsFilm )
IT0179.01 – INOV-C+
Co-Investigador Responsável (Co-IR)
Universidade de Coimbra
2018/10 - 2021/09 Doctoral Training Partnership 2018-19 - Next generation bio-based antimicrobial agents
GEN1227-226
Investigador responsável
Engineering and Physical Sciences Research Council
2019/02 - 2021/08 Diterpenoid-based scaffolds for enabling skin repair (DipSkinRepair)
S18-23
Investigador responsável
Tenovus Scotland
2017/09 - 2019/09 Chancellor's Research Fellow (Start-up funds)
GEN1227-201
Investigador responsável
University of Strathclyde
2013/11 - 2018/10 Understanding chronic pain and new druggable targets: Focus on glial-opioid receptor interface (GLORIA)
602919
Investigador
Seventh Framework Programme
2014/05 - 2018/04 Synthesis of novel abietane-type diterpenoids with anticancer activity (doctoral scholarships)
264020
Investigador responsável
Helsingin Yliopisto
2016/09 - 2018/01 Sustainable hydrophobic materials for antimicrobial coatings (RESICELL)
1297/31/2016
Investigador responsável
Business Finland
2015 - 2016 Fully renewable bioactive textiles II
WBS4704219
Investigador responsável
Huonekalusäätio
2013/01 - 2015/12 Wood diterpenes as leads to new anti-biofilm strategies (WOODYFILM)
decision 264020
Investigador
Suomen Akatemia
2011/09 - 2015/12 Betulins, abietanes and resin acids as novel lead compounds for cancer (BARC)
decision 252308
Investigador
Suomen Akatemia
2014 - 2015 Fully renewable bioactive textiles
WBS4703795
Investigador responsável
Huonekalusäätio
2011/06 - 2014/05 FuBio Joint Research 2
Future Biorefinery - FuBio Joint Research 2
Investigador
Business Finland
2013 - 2014 Synthesis of Oxamniquine Derivatives for Cancer Treatment. A Drug Repositioning Approach
WBS4703311
Investigador
Magnus Ehrnroothin Säätiö
2011/01/01 - 2013/12/31 Projecto Estratégico - UI 313 - 2011-2012
PEst-C/QUI/UI0313/2011
Universidade de Coimbra, Portugal
Fundação para a Ciência e a Tecnologia
Concluído
Produções

Publicações

Artigo em conferência
  1. Moreira, Vania; Mäki-Opas, L.; Hämäläinen, M.; Moilanen, L.; Ahonen, T; Haavikko, R.; Muraki, M.; Yli-Kauhaluoma, J.; Moilainen, E.. "Pyrazine-fused triterpenoids block transient receptor potential ankyrin-1 (TRPA1) ion channel in vitro and inhibit TRPA1-mediated acute inflammation in vivo.". Trabalho apresentado em meeting of the Finnish Society for Rheumatology, Turku, 2017.
    Publicado
  2. Moreira, Vania; Vahermo, M.; Manner, S.; Skogman, M.; Fallarero A; Yli-Kauhaluoma, Jari. "Design and synthesis of new bioactive diterpenoids". Trabalho apresentado em EFMC-ISMC 2014, 2014.
    Publicado
  3. Moreira, Vania; Jaffe, C.; Kopelyanskly, D; Nasereddin, A.; Yli-Kauhaluoma, J.. "Resin acids derived diterpenes as antileishmanial compounds". Trabalho apresentado em EFMC-ISMC 2014, 2014.
    Publicado
  4. Vânia M Moreira; Jorge A. R. Salvador; Ana Matos Beja; José A. Paixão; Tadas S. Vasaitis; Vincent C. O. Njar. "C16 and C17-Heterocycle Bearing Androstanes. CYP17 Inhibition Studies and Multiple Effects on Prostate Cancer Cells". Trabalho apresentado em 4th BBBB International Conference on Pharmaceutical Sciences, 2011.
    Publicado
  5. Moreira, Vania; Salvador, Jorge A. R.. "The multiple effects of CYP17 inhibitors on prostate cancer cells". Trabalho apresentado em EFMC-ISMC 2010, Brussels, 2010.
    Publicado
  6. Moreira, Vania; Salvador, Jorge A. R.. "Multiple targeted actions of CYP17 inhibitors on prostate cancer cells". Trabalho apresentado em 1st National meeting on medicinal chemistry, Porto, 2008.
    Publicado
  7. Moreira, Vania; Salvador, Jorge A. R.; Sa e Melo, L. M.; Hanson, J; Marques, Andreia; Simoes, Sergio. "New 5ß,6ß-epoxysteroids with cytotoxic activity". Trabalho apresentado em Joint meeting on medicinal chemistry, Vienna, 2005.
    Publicado
Artigo em revista
  1. Vânia Moreira. "O Potencial dos Ácidos Resínicos na Descoberta de Novos Fármacos Antimicrobianos". Boletim da Sociedade Portuguesa de Química 47 170 (2023): 165-171. http://dx.doi.org/10.52590/m3.p707.a30002710.
    10.52590/m3.p707.a30002710
  2. Tiina J. Ahonen; Choa P. Ng; Beatriz Farinha; Bárbara Almeida; Bruno L. Victor; Christopher Reynolds; Eija Kalso; et al. "Probing the Interactions of Thiazole Abietane Inhibitors with the Human Serine Hydrolases ABHD16A and ABHD12". ACS Medicinal Chemistry Letters (2023): https://doi.org/10.1021/acsmedchemlett.3c00313.
    10.1021/acsmedchemlett.3c00313
  3. Laura D. Carreira; Rita I. Oliveira; Vânia M. Moreira; Jorge A. R. Salvador. "Ubiquitin-specific protease 7 (USP7): an emerging drug target for cancer treatment". Expert Opinion on Therapeutic Targets (2023): https://doi.org/10.1080/14728222.2023.2266571.
    10.1080/14728222.2023.2266571
  4. Jean-Jacques Helesbeux; Laura Carro; Florence O. McCarthy; Vânia M. Moreira; Francesca Giuntini; Niamh O’Boyle; Susan E. Matthews; et al. "29th Annual GP2A Medicinal Chemistry Conference". Pharmaceuticals (2021): https://doi.org/10.3390/ph14121278.
    10.3390/ph14121278
  5. Mullen, Declan; Wan, Xing; Takala, Timo; Saris, Per E; Moreira, Vania. "Precision Design of Antimicrobial Surfaces". Front. Med. Technol. (2021): https://doi.org/10.3389/fmedt.2021.640929.
    10.3389/fmedt.2021.640929
  6. Rae F. Bell; Vânia M. Moreira; Eija A. Kalso; Jari Yli-Kauhaluoma. "Liquorice for pain?". Therapeutic Advances in Psychopharmacology (2021): https://doi.org/10.1177/20451253211024873.
    10.1177/20451253211024873
  7. Maiju Rinne; Kert Mätlik; Tiina Ahonen; Fabio Vedovi; Giovanni Zappia; Vânia M. Moreira; Jari Yli-Kauhaluoma; et al. "Mitoxantrone, pixantrone and mitoxantrone (2-hydroxyethyl)piperazine are toll-like receptor 4 antagonists, inhibit NF-¿B activation, and decrease TNF-alpha secretion in primary microglia". European Journal of Pharmaceutical Sciences 154 (2020): 105493-105493. https://doi.org/10.1016/j.ejps.2020.105493.
    10.1016/j.ejps.2020.105493
  8. Moreira, Vania. "Non-leaching, Highly Biocompatible Nanocellulose Surfaces That Efficiently Resist Fouling by Bacteria in an Artificial Dermis Model". ACS Applied Bio Materials (2020): http://dx.doi.org/10.1021/acsabm.0c00203.
    10.1021/acsabm.0c00203
  9. Ilari Mäki-Opas; Mari Hämäläinen; Lauri J. Moilanen; Raisa Haavikko; Tiina J. Ahonen; Sami Alakurtti; Vânia M. Moreira; et al. "Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo". ACS Chemical Neuroscience 10 (2019): 2848-2857. https://doi.org/10.1021/acschemneuro.9b00083.
    10.1021/acschemneuro.9b00083
  10. Ghada Hassan; Nina Forsman; Xing Wan; Leena Keurulainen; Luis M. Bimbo; Leena-Sisko Johansson; Nina Sipari; et al. "Dehydroabietylamine-Based Cellulose Nanofibril Films: A New Class of Sustainable Biomaterials for Highly Efficient, Broad-Spectrum Antimicrobial Effects". ACS Sustainable Chemistry & Engineering 7 5 (2019): 5002-5009. https://doi.org/10.1021%2Facssuschemeng.8b05658.
    10.1021/acssuschemeng.8b05658
  11. Tiina J. Ahonen; Juha R. Savinainen; Jari Yli-Kauhaluoma; Eija Kalso; Jarmo T. Laitinen; Vânia M. Moreira. "Discovery of 12-Thiazole Abietanes as Selective Inhibitors of the Human Metabolic Serine Hydrolase hABHD16A". ACS Medicinal Chemistry Letters 9 (2018): 1269-1273. https://doi.org/10.1021/acsmedchemlett.8b00442.
    10.1021/acsmedchemlett.8b00442
  12. Laura E. Kolsi; Ana S. Leal; Jari Yli-Kauhaluoma; Karen T. Liby; Vânia M. Moreira. "Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1". Scientific Reports 8 1 (2018): 15923. https://doi.org/10.1038/s41598-018-34131-1.
    10.1038/s41598-018-34131-1
  13. Laura E. Kolsi; Jari Yli-Kauhaluoma; Vânia M. Moreira. "Catalytic, Tunable, One-Step Bismuth(III) Triflate Reaction with Alcohols: Dehydration Versus Dimerization". ACS Omega 3 (2018): 8836-8842. https://doi.org/10.1021/acsomega.8b01401.
    10.1021/acsomega.8b01401
  14. Ahonen TJ; Rinne M; Grutschreiber P; Mätlik K; Airavaara M; Schaarschmidt D; Lang H; et al. "Synthesis of 7ß-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors.". European journal of medicinal chemistry 151 (2018): 495-507. https://doi.org/10.1016/j.ejmech.2018.02.074.
    10.1016/j.ejmech.2018.02.074
  15. Moreira, Vania. "Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents.". European journal of medicinal chemistry (2017): https://doi.org/10.1016/j.ejmech.2017.11.070.
    10.1016/j.ejmech.2017.11.070
  16. Kolsi, Laura E.; Krogerus, Sara; Brito, Vanessa; Rüffer, Tobias; Lang, Heinrich; Yli-Kauhaluoma, Jari; Silvestre, Samuel M.; Moreira, Vânia M.. "Regioselective Benzylic Oxidation of Aromatic Abietanes: Application to the Semisynthesis of the Naturally Occurring Picealactones A, B and C". ChemistrySelect 2 24 (2017): 7008-7012. http://dx.doi.org/10.1002/slct.201701477.
    10.1002/slct.201701477
  17. Andreas Helfenstein; Mikko Vahermo; Dorota A. Nawrot; Fatih Demirci; Gökalp Iscan; Sara Krogerus; Jari Yli-Kauhaluoma; Vânia M. Moreira; Päivi Tammela. "Antibacterial profiling of abietane-type diterpenoids". Bioorganic & Medicinal Chemistry 25 1 (2017): 132-137. https://doi.org/10.1016%2Fj.bmc.2016.10.019.
    10.1016/j.bmc.2016.10.019
  18. Chaaban, Ibrahim; El Khawass, El Sayeda M.; Abd El Razik, Heba A.; El Salamouni, Nehad S.; Redondo-Horcajo, Mariano; Barasoain, Isabel; Díaz, José Fernando; Yli-Kauhaluoma, Jari; Moreira, Vânia M.. "Synthesis and Anti-Proliferative Activity of Sulfanyltriazolylnaphthalenols and Sulfanyltriazolylnaphthalene-1,4-diones". Archiv der Pharmazie 349 9 (2016): 749-761. http://dx.doi.org/10.1002/ardp.201600134.
    10.1002/ardp.201600134
  19. Pirttimaa M; Nasereddin A; Kopelyanskiy D; Kaiser M; Yli-Kauhaluoma J; Oksman-Caldentey KM; Brun R; et al. "Abietane-Type Diterpenoid Amides with Highly Potent and Selective Activity against Leishmania donovani and Trypanosoma cruzi.". Journal of Natural Products 79 (2016): 362-368. https://doi.org/10.1021/acs.jnatprod.5b00990.
    10.1021/acs.jnatprod.5b00990
  20. Laavola M; Haavikko R; Hämäläinen M; Leppänen T; Nieminen R; Alakurtti S; Moreira VM; Yli-Kauhaluoma J; Moilanen E. "Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo". Journal of Natural Products 79 (2016): 274-280. https://doi.org/10.1021/acs.jnatprod.5b00709.
    10.1021/acs.jnatprod.5b00709
  21. Vahermo, Mikko; Krogerus, Sara; Nasereddin, Abdelmajeed; Kaiser, Marcel; Brun, Reto; Jaffe, Charles L.; Yli-Kauhaluoma, Jari; Moreira, Vânia M.. "Antiprotozoal activity of dehydroabietic acid derivatives against Leishmania donovani and Trypanosoma cruzi". MedChemComm 7 3 (2016): 457-463. http://dx.doi.org/10.1039/c5md00498e.
    10.1039/c5md00498e
  22. Moreira, Vania. "New derivatives of dehydroabietic acid target planktonic and biofilm bacteria in Staphylococcus aureus and effectively disrupt bacterial membrane integrity". European Journal of Medicinal Chemistry (2015): https://doi.org/10.1016/j.ejmech.2015.07.038.
    10.1016/j.ejmech.2015.07.038
  23. Härmä V; Haavikko R; Virtanen J; Ahonen I; Schukov HP; Alakurtti S; Purev E; et al. "Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development.". PLoS ONE 10 (2015): e0126111. https://doi.org/10.1371/journal.pone.0126111.
    10.1371/journal.pone.0126111
  24. Bromann, K.; Viljanen, K.; Moreira, V. M.; Yli-Kauhaluoma, J.; Ruohonen, L.; Nakari-Setala, T.. "Isolation and purification of ent-pimara-8(14),15-diene from engineered Aspergillus nidulans by accelerated solvent extraction combined with HPLC". Analytical Methods 6 4 (2014): 1227-1234. https://doi.org/10.1039/C3AY41640B.
    10.1039/c3ay41640b
  25. Chaaban, Ibrahim; El Khawass, El Sayeda M.; Abd El Razik, Heba A.; El Salamouni, Nehad S.; Redondo-Horcajo, Mariano; Barasoain, Isabel; Diaz, J. Fernando; Yli-Kauhaluoma, Jari; Moreira, Vania M.. "Synthesis and biological evaluation of new oxadiazoline-substituted naphthalenyl acetates as anticancer agents". European journal of medicinal chemistry 87 (2014): 805-13. https://doi.org/10.1016/j.ejmech.2014.10.015.
    10.1016/j.ejmech.2014.10.015
  26. Moreira, Vania M.; Salvador, Jorge A. R.; Simoes, Sergio; Destro, Federica; Gavioli, Riccardo. "Novel oleanolic vinyl boronates: Synthesis and antitumor activity". European Journal of Medicinal Chemistry 63 (2013): 46-56. https://doi.org/10.1016/j.ejmech.2013.01.040.
    10.1016/j.ejmech.2013.01.040
  27. Fallarero A; Kujala J; Moreira VM; Rajaratnam M; Skogman M; Vuorela P; Yli-Kauhaluoma J. "(+)-Dehydroabietic Acid, an Abietane-Type Diterpene, Inhibits Staphylococcus aureus Biofilms in Vitro.". International Journal of Molecular Sciences 14 (2013): 12054-12072. https://doi.org/10.3390/ijms140612054.
    10.3390/ijms140612054
  28. Napolitano, Francesco; Zhao, Yan; Moreira, Vania M.; Tagliaferri, Roberto; Kere, Juha; D'Amato, Mauro; Greco, Dario. "Drug repositioning: a machine-learning approach through data integration". Journal of Cheminformatics 5 (2013): 30. https://doi.org/10.1186/1758-2946-5-30.
    10.1186/1758-2946-5-30
  29. Jorge A. R. Salvador; Samuel M. Silvestre; Vânia M Moreira. "Recent Developments in Oxidative Processes in Steroid Chemistry". Current Organic Chemistry 16 (2012): 1243-1276. https://doi.org/10.2174/138527212800564204.
  30. Salvador, Jorge A R; Moreira, Vânia M; Pinto, Rui M A; Leal, Ana S; Paixão, José A. "Efficient oxidation of oleanolic acid derivatives using magnesium bis(monoperoxyphthalate) hexahydrate (MMPP): A convenient 2-step procedure towards 12-oxo-28-carboxylic acid derivatives". Beilstein Journal of Organic Chemistry 8 (2012): 164-169. http://dx.doi.org/10.3762/bjoc.8.17.
    10.3762/bjoc.8.17
  31. Salvador, Jorge A. R.; Moreira, Vânia M.; Gonçalves, Bruno M. F.; Leal, Ana S.; Jing, Yongkui. "Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs". Natural Product Reports 29 12 (2012): 1463. http://dx.doi.org/10.1039/c2np20060k.
    10.1039/c2np20060k
  32. Salvador, Jorge A. R.; Moreira, Vânia M.; Pinto, Rui M. A.; Leal, Ana S.; Le Roux, Christophe. "Bismuth(III) Triflate-Based Catalytic Direct Opening of Oleanolic Hydroxy-¿-lactones to Afford 12-Oxo-28-carboxylic Acids". Advanced Synthesis & Catalysis 353 14-15 (2011): 2637-2642. http://dx.doi.org/10.1002/adsc.201100155.
    10.1002/adsc.201100155
  33. Vânia M Moreira; Jorge A. R. Salvador; Ana Matos Beja; José A. Paixão. "The reaction of azoles with 17-chloro-16-formylandrosta-5,16-dien-3-yl-acetate: Synthesis and structural elucidation of novel 16-azolylmethylene-17-oxoandrostanes.". Steroids 76 (2011): 582-587. https://doi.org/10.1016/j.steroids.2011.02.009.
  34. Manuela R. Silva; Vânia M Moreira; Cláudia Cardoso; Ana Matos Beja; Jorge A. R. Salvador. "3-Oxoandrosta-4,6-dien-17beta-yl-2'-methyl-1H-imidazole-1-carboxylate and 3-oxo-5a-androst-17beta-yl-2'-methyl-1H-imidazole-1-carboxylate: C¿H..p and p¿¿¿p intermolecular interactions". Acta Crystallographica. Section C: Crystal Structure Communications C65 (2009): o88-o91. https://doi.org/10.1107/S0108270109003278.
  35. Vânia M Moreira; Tadas S. Vasaitis; Zhiyong Guo; Vincent C. O. Njar; Jorge A. R. Salvador. "Synthesis of novel C17 steroidal carbamates. Studies on CYP17 action, androgen receptor binding and function, and prostate cancer cell growth". Steroids 73 (2008): 1217-1227. https://doi.org/10.1016/j.steroids.2008.05.010.
  36. Moreira, V.; Salvador, J.; Vasaitis, T.; Njar, V.. "CYP17 Inhibitors for Prostate Cancer Treatment – An Update". Current Medicinal Chemistry 15 9 (2008): 868-899. http://dx.doi.org/10.2174/092986708783955428.
    10.2174/092986708783955428
  37. Manuela R. Silva; Vânia M Moreira; Cláudia Cardoso; Ana M. Beja; Jorge A. R. Salvador. "1H-and 2H-indazole derivatives of androsta-5,16-dien-3ß-ol". Acta Crystallographica. Section C: Crystal Structure Communications C64 (2008): o217-o219. https://doi.org/10.1107/S0108270108005842.
  38. Manuela R. Silva; Vânia M Moreira; Cláudia Cardoso; Ana Matos Beja; Jorge A. R. Salvador. "Conformation of 17-Chloro-16-formylandrosta-5,16-dien-3ß-yl acetate and 17-chloroandrosta-5,16-dien-3ß-yl acetate". Acta Crystallographica. Section C: Crystal Structure Communications C64 (2008): o529-o531. https://doi.org/10.1107/S0108270108025997.
  39. Jorge A. R. Salvador; Samuel M. Silvestre; Vânia M Moreira. "Catalytic Epoxidation and syn-Dihydroxylation Reactions in Steroid Chemistry". Current Organic Chemistry 12 (2008): 492-522. https://doi.org/10.2174/138527208784083897.
  40. Ramos Silva, Manuela; Matos Beja, Ana; Moreira, Vânia M.; Santos, Rita C.; Salvador, Jorge A. R.. "3-Oxoandrost-4-en-17ß-yl 1H-imidazole-1-carboxylate". Acta Crystallographica Section E Structure Reports Online 63 12 (2007): o4824-o4824. http://dx.doi.org/10.1107/s1600536807057625.
    10.1107/s1600536807057625
  41. Vânia M Moreira; Tadas S Vasaitis; Vincent C. O. Njar; Jorge A. R. Salvador. "Synthesis and evaluation of novel 17-indazole androstene derivatives designed as CYP17 inhibitors". Steroids 72 (2007): 939-948. https://doi.org/10.1016/j.steroids.2007.08.004.
  42. Jorge A. R. Salvador; Samuel M. Silvestre; Vânia M Moreira. "Catalytic oxidative processes in steroid chemistry: allylic oxidation, ß-selective epoxidation, alcohol oxidations and remote functionalization reactions". Current Organic Chemistry 10 (2006): 2227-2257. https://doi.org/10.2174/138527206778742641.
  43. Jorge A. R. Salvador; Vânia M Moreira; James R. Hanson; Rui A. Carvalho. "One-pot, high yield synthesis of a-ketols from delta5-steroids". Steroids 71 (2005): 266-272. https://doi.org/10.1016/j.steroids.2005.11.002.
Capítulo de livro
  1. Vânia M Moreira. "Carbocations". In Organic Reaction Mechanisms 2019: An annual survey covering the literature dated January to December 2019, 257-285. John Wiley & Sons Ltd, 2023.
    10.1002/9781119608288.ch6
  2. Moreira, Vania. "Carbocations". In Organic Reaction Mechanisms 2018: An annual survey covering the literature dated January to December 2018, 227-245. John Wiley & Sons Ltd, 2021.
    Publicado • 10.1002/9781119531975
  3. Jorge A. R. Salvador; Vânia M Moreira; Samuel M. Silvestre; R. Salvador, Jorge A.; M., Vania; M., Samuel. "Steroidal CYP17 Inhibitors for Prostate Cancer Treatment. From Concept to Clinic.". In Advances in Prostate Cancer, editado por Gerhard Hamilton, 275-304. INTECHopen, 2013.
    10.5772/45948
  4. R. Salvador, Jorge A.; M., Vania. "Highlights of Natural Products in Prostate Cancer Drug Discovery". In Prostate Cancer - From Bench to Bedside, editado por Spiess, {Philippe E.. InTech, 2011.
    10.5772/27401
  5. Jorge A. R. Salvador; Vânia M Moreira. "Semisynthetic Pentacyclic Triterpenoids in the Cancer Setting: Ursolic Acid and its Derivatives". editado por Salvador, {Jorge A. R.. Nova Science Publishers, 2010.
    Publicado
  6. Jorge A. R. Salvador; Vânia M Moreira. "Natural Products Action on Prostate Cancer Cell Growth, Signaling and Survival". editado por Meredith, {Alan T.. Nova Science Publishers, 2009.
    Publicado
Tese / Dissertação
  1. Moreira, Vania. "Novos esteróides inibidores da biossíntese de androgénios". Doutoramento, Universidade de Coimbra, 2008.

Propriedade Intelectual

Patente
  1. Vânia M Moreira; Adyary Fallarero; Jari Tapani Yli-Kauhaluoma; Pia Vuorela; Mikko Martti Antero Vahermo. 2016. "Abietane-type diterpenoids (WO 2016/051013 A1)".
Atividades

Apresentação oral de trabalho

Título da apresentação Nome do evento
Anfitrião (Local do evento)
2022/11 Round table discussion: "Ciência em Portugal" VIII Encontro Científico do Núcleo de Estudantes de Química (NEQAAC)
(Coimbra, Portugal)
2022/04 "Highlights of naturally occurring terpenes and flavonoids in drug discovery for pain". Part of the workshop entitled “Plants for pain: current use, future possibilities and concerns”. EFIC2022 – Pain in Europe
(Dublin, Irlanda)
2021/04/08 Abietane-based nanocellulose films: Fully sustainable, anionic, biocompatible and non-leaching surfaces to efficiently prevent bacterial fouling (paper 3553643) ACS Spring 2021. Macromolecular Chemistry: The Second Century
(Estados Unidos)
2021/03/30 Painel Química Farmacêutica Biomédica Tem Futuro! III Semana de Farmácia Biomédica
(Portugal)
2021/03/15 Incursions into the untapped medicinal potential of the abietane-type diterpenoids PDBEB Advanced Course- Fighting infection
CNC, Coimbra (Portugal)
2021/03/04 The medicinal potential of the abietanes from rosin Research Seminar Series 2020-2021
Trinity College Dublin, Ireland
2021/01/30 Saídas Profissionais em Química Farmacêutica Semana de Farmácia Biomédica: Biomédica Tem Futuro!
Comissão de Curso da Licenciatura em Farmácia Biomédica, FFUC, Coimbra (Portugal)
2021/01/12 Explorations into the medicinal potential of the abietanes: a tale of innovative antimicrobial compounds and materials Drug Research Webinar series
Faculty of Pharmacy, University of Helsinki, Finland (Finlândia)
2021/01/07 Projectos de investigação na FFUC PharmCareer NEF, FFUC, Coimbra
NEF-AAC, Coimbra (Portugal)
2020/09/19 Explorations into the medicinal potential of the abietanes: a tale of innovative antimicrobial compounds and materials 2nd CIBB Innovative Therapies Retreat 2020
(Coimbra, Portugal)
2020/01 Harnessing the power of resin acids for innovative antimicrobial research 13th National Organic Chemistry Meeting (13ENQO) and the 6th National Medicinal Chemistry Meeting (6ENQT)
(Aveiro, Portugal)
2019/10 Diterpenoid-based biomaterials for antimicrobial and wound-healing effects Tenovus Scotland Symposium
(Perth, Reino Unido)
2019/08 Resin-acids driven innovations in antimicrobial research GP2A, Nottingham, 2019
(Nottingham, Reino Unido)
2018/12 Harnessing the power of resin acids for innovative antimicrobial research SIPBS Research Day
(Glasgow, Reino Unido)
2018/10 Bio-based hybrid antimicrobial surfaces Invited talk at the Institute during research visit
Leibniz-Institut für Polymerforstung e.V. (Dresden)
2018/07 Bio-based hybrid antimicrobial surfaces Invited lecture at the Department
Biomedical Engineering Department, University of Strathclyde (Glasgow, Reino Unido)
2017/12 Resin-acids based antimicrobial and anti-biofilm solutions 2nd International Caparica Christmas Congress on Translational Chemistry
(Caparica, Portugal)
2016/05 Research activities at the University of Helsinki within the theme of COST Action 1307 Working Group 1 and 4 meeting of COST Action CM1307
(Porto, Portugal)
2015/08 Synthesis of new opioid derivatives 3rd Project Meeting of the GLORIA consortium
(Vienna, Áustria)
2013/08 Design and Synthesis of New Bioactive Diterpenes 11th FIPS & FinMedChem
(Helsinki)
2013/06 Oleanolic vinyl boronates. Antiproliferative activity and proteasome inhibition studies Nordic Natural Products Conference
(Turku, Finlândia)
2011/09 C16 and C17-Heterocyclic bearing androstanes. CYP17 inhibition studies and multiple effects on prostate cancer cells 4th BBBB – Bled International Conference on Pharmaceutical Sciences
(Bled, Eslovénia)
2011/07 Multiple Actions of CYP17 Inhibitors on Prostate Cancer Cells VII Joint Meeting on Medicinal Chemistry
(Catania, Itália)
2008/11 Multiple targeted action of CYP17 inhibitors on prostate cancer cells 1º Encontro Nacional de Química Terapêutica
(Porto, Portugal)
2007/12 Inibidores da CYP17 para o tratamento do cancro da próstata II Congresso Científico Anual, XXI Anos NEF/AAC
(Coimbra, Portugal)

Orientação

Título / Tema
Papel desempenhado
Curso (Tipo)
Instituição / Organização
2023/11 - Atual Rifamicins as bacterial RNAP inhibitors
Orientador
Universidade de Coimbra, Portugal
2023/11 - Atual Targeting bacterial biofilms with azole -based compounds
Orientador
Universidade de Coimbra, Portugal
2023/11 - Atual Targeting "quorum-sensing" in bacterial biofilms
Orientador
Universidade de Coimbra, Portugal
2023/10/01 - Atual Novos diterpenóides semi-sintéticos para o tratamento das infeções resistentes
Orientador
PhD (Doutoramento)
Universidade de Coimbra, Portugal
2023/10 - Atual Development of new alkaloid derivatives to target drug resistance in cancer
Coorientador
MSc (Mestrado)
Universidade de Coimbra, Portugal
2023/10 - Atual Análises qualitativas de produtos farmacêuticos e soluções terapêuticas em HPLC
Coorientador
MSc (Mestrado)
Universidade de Coimbra, Portugal
2022/10 - Atual Natural product-based anticancer agents for the inhibition of USP7
Coorientador
PhD (Doutoramento)
Universidade de Coimbra, Portugal
2023/10 - 2033/07 Novos compostos antifúngicos no tratamento das dermatofitoses e onicomicoses
Orientador
MICF (Mestrado)
Universidade de Coimbra, Portugal
2023/10 - 2033/02 Derivados do (+)-Esclareólido como Antifúngicos: Investigação e Síntese
Orientador
Licenciatura- Estágios do NEF (Outra)
Universidade de Coimbra, Portugal
2023 - 2033 Síntese de diterpenóides antimicrobianos
Orientador
Licenciatura - Estágios do NEF (Outra)
Universidade de Coimbra, Portugal
2014/09 - 2023/11 Synthesis of chemical probes for studying neuroinflammatory and chronic pain conditions
Orientador
PhD (Doutoramento)
Helsingin Yliopisto, Finlândia
2021/11 - 2022/09 Novas abordagens terapêuticas para infeções fúngicas invasivas
Orientador
MICF (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022/05 - 2022/07 Antimicrobial PHAs
Orientador
Licenciatura - Estágios do NEF (Outra)
Universidade de Coimbra, Portugal
2021/11 - 2022/07 Abordagem farmacológica à leishmaniose canina
Orientador
MICF (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2018/10 - 2022/06 Next generation bio-based antimicrobial agents
Orientador
PhD (Doutoramento)
University of Strathclyde, Reino Unido
2020/12 - 2021/09 Biofilms in the drug discovery of new antimicrobials
Orientador
MICF (Mestrado)
Universidade de Coimbra, Portugal
2020/12 - 2021/09 Anti-biofilm drug discovery
Orientador
MICF (Mestrado)
Universidade de Coimbra, Portugal
2020/12 - 2021/07 Abiraterone Acetate in the Treatment of Advanced Prostatic Cancer
Orientador
MICF (Mestrado)
Universidade de Coimbra, Portugal
2020/10 - 2021/03 Biofilmes e a necessidade de uma terapêutica eficaz
Orientador
Licenciatura- Estágios do NEF (Outra)
Universidade de Coimbra, Portugal
2016/09 - 2021/02 Synthesis of Antimicrobial Surfaces and Compounds to Target Resistant Staphylococcus aureus
Orientador
PhD (Doutoramento)
Helsingin Yliopisto, Finlândia
2020/09 - 2020/12 Antimicrobial abietanes
Orientador
Licenciatura - Estágios do NEF (Outra)
Universidade de Coimbra, Portugal
2020/01 - 2020/08 Drug-likeness of bioactive compounds
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2019/10 - 2020/05 The anticancer and antimicrobial activities of abietane-type diterpenoids
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2019/10 - 2020/05 Recent developments in antimicrobial surfaces
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2019/10 - 2020/05 Anti-biofilm drug discovery
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2016/09 - 2020/04/24 Multifunctional coatings for plant-based textiles and other cellulosic substrates
Coorientador
PhD (Doutoramento)
Helsingin Yliopisto, Finlândia
2019/05 - 2019/08 Development of an in-silico model for inhibition of cell wall synthesis in Staphylococcus aureus
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2019/05 - 2019/08 Dehydroabietic acid derivatives targeting Staphylococcus aureus infections as prevention of Squamous Cells Carcinoma (SCC) of the skin
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2019/05 - 2019/08 Investigation of Biocompatibility and Antimicrobial activity of diterpenoid amine-cellulose constructs
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2019/05 - 2019/08 An investigation into the antimicrobial properties of diterpenoid amine-cellulose constructs
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2018/10 - 2019/03 CYP17 inhibitors in advanced prostatic cancer
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2018/10 - 2019/03 The impact of biofilms in the drug discovery of new antimicrobials
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2018/05 - 2019/03 Anti-biofilm activity testing in drug discovery
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2014 - 2019/01 Synthesis of Abietane-Type Diterpenoids with Anticancer Activity
Orientador
PhD (Doutoramento)
Helsingin Yliopisto, Finlândia
2018/05 - 2018/08 The anticancer activity of picealactones
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2018/05 - 2018/08 Cellulose antimicrobial solutions
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2017/05 - 2017/08 Targeting metabolic serine hydrolases for the development of new anti-inflammatory drug leads
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2017/05 - 2017/08 Exploiting the potential of abietane-type diterpenoids for the design and synthesis of antimicrobial and anti-biofilm agents
Orientador
MSc (Mestrado)
University of Strathclyde, Reino Unido
2016/09 - 2016/12 New diterpenoids in chronic pain treatment
Orientador
MSc (Mestrado)
Helsingin Yliopisto, Finlândia
2016/09 - 2016/12 Synthesis of dehydroabietic acid derivatives prepared using eco-friendly oxidation reagents
Orientador
Helsingin Yliopisto, Finlândia
2016 - 2016 Synthesis of 5-methylene(thio)ureas (thio)barbiturates as potential xanthine oxidase inhibitors
Coorientador
MSc (Mestrado)
Helsingin Yliopisto, Finlândia
2015 - 2016 Benzylic oxidations of dehydroabietic acid derivatives at positions 7 and 15
Orientador
MSc (Mestrado)
Helsingin Yliopisto, Finlândia
2015 - 2016 Synthesis of abietic and dehydroabietic acid derivatives to target bacterial biofilms
Orientador
MSc (Mestrado)
Helsingin Yliopisto, Finlândia
2015 - 2015 Derivatives of abietic acid and their bioactivity
Coorientador
MSc (Mestrado)
Helsingin Yliopisto, Finlândia
2012 - 2015 Synthesis of betulins with new bioactivities
Coorientador
PhD (Doutoramento)
Helsingin Yliopisto, Finlândia
2014/06 - 2014/09 Synthesis and characterization of chemical compounds
Orientador
Helsingin Yliopisto, Finlândia
2014/04 - 2014/07 Synthesis and characterization of morphine derivatives
Orientador
Helsingin Yliopisto, Finlândia
2013 - 2014 Modification of resin acids for the production of biologically active molecules
Orientador
MSc (Mestrado)
Helsingin Yliopisto, Finlândia
2013/06 - 2013/09 Synthesis of 1,2,3,4-tetrahydro-[1,7]-naphthyridines
Orientador
Helsingin Yliopisto, Finlândia
2012 - 2013 Design and synthesis of some novel phenolic compounds and their quinone oxidation products of potential biological activities
Coorientador
PhD (Doutoramento)
Helsingin Yliopisto, Finlândia
2012 - 2013 Lääkeaineisiin ja rohdoksiin liittyvien tutkimuksellisten kokeellisten töiden kehittäminen lukion kemianopetukseen
Coorientador
MSc (Mestrado)
Helsingin Yliopisto, Finlândia

Organização de evento

Nome do evento
Tipo de evento (Tipo de participação)
Instituição / Organização
2024/08/28 - 2024/08/31 32nd Annual Meeting of the GP2A, Coimbra, Portugal (2024/08/28 - 2024/08/31)
Encontro (Presidente da Comissão Organizadora)
Universidade de Coimbra, Portugal
2022/08/24 - 2022/08/26 GP2A 2022 30th Annual Conference (2022 - 2022)
Conferência (Membro da Comissão Organizadora)
The University of Dublin Trinity College, Irlanda
2022/06 - 2022/06 Encontro anual CIBB 2022 (2022/06 - 2022/06)
Oficina (workshop) (Membro da Comissão Organizadora)
Universidade de Coimbra, Portugal
2021/08/25 - 2021/08/27 GP2A 2021 - 29th Annual Conference (Online) (2021 - 2021)
Congresso (Membro da Comissão Organizadora)
2021/03/05 - 2021/03/05 GP2A 2021 online conference: Drug discovery in the era of antimicrobial resistance (2021 - 2021)
Conferência (Membro da Comissão Científica)
2020/08/27 - 2020/08/27 28th Annual GP2A Conference (2020 - 2020)
Conferência (Membro da Comissão Científica)
2016/09 - 2016/09 INTERNATIONAL SCIENTIFIC ADVISORY COMMITTEE, XXIV EFMC International Symposium on Medicinal Chemistry 2016 (2016/09 - 2016/09)
2010/11 - 2010/11 2nd National Meeting on Medicinal Chemistry (2010/11 - 2010/11)
Conferência (Membro da Comissão Organizadora)

Júri de grau académico

Tema
Tipo de participação
Nome do candidato (Tipo de grau)
Instituição / Organização
2024/02 Combining synthesis inspired in natural products and nanotechnology: a rational strategy to treat biofilm infections
Arguente principal
Daniela Raquel Pontes Loureiro (Doutoramento)
Universidade do Porto, Portugal
2023/10 Proteolysis-targeting chimeras (PROTACs): A precision medicine strategy for cancer treatment
Arguente principal
Inês Maria Nunes da Silva (Mestrado)
Universidade de Coimbra, Portugal
2023/09 1H,3H-Pirrolo[1,2-C]tiazóis quirais no tratamento do cancro colorretal: Síntese de novos derivados do composto líder MANIO
Arguente principal
Adelino Manuel Reis Pereira (Mestrado)
Universidade de Coimbra, Portugal
2023/09 Click chemistry derived 1,2,3-triazole hybrids in lung cancer therapy
Arguente principal
José Maria Canelas gomes Teixeira (Mestrado)
Universidade de Coimbra, Portugal
2023/03 Targeting necroptosis: discovery and optimization of novel Ripk1 inhibitors
Arguente principal
Mariana Rita Silvestre Baleia (Mestrado)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2023/02 Target-based and Phenotypic Studies towards the Discovery of Antimicrobial Adjuvants
Arguente principal
Fernando André Pereira Marques Durães (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2022/11 Preparation and biological evaluation of new triterpenoid derivatives of glycyrrhetinic acid
Arguente
Daniela Pereira Santana Alho (Doutoramento)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022/10 Radiofármacos utilizados em terapia
Arguente principal
Ivanna Stakhiv (Mestrado)
Universidade de Coimbra Faculdade de Farmácia, Portugal
2022/09 Bio-triggered triazenes: a novel approach to release triazene alkylating agents
Arguente
Cláudia Braga (Doutoramento)
Universidade de Lisboa Faculdade de Farmácia, Portugal
2021/12/14 Overcoming environmental problems associated with antifouling agents: synthesis of Nature-inspired nontoxic agents and immobilization in polymeric coatings
Arguente principal
Ana Rita da Conceição Neves (Doutoramento)
Universidade do Porto Faculdade de Farmácia, Portugal
2020/11/05 Ubiquitin Specific Protease 7 (USP7) Inhibitors as New Agents in Cancer Treatment
Arguente principal
Rui Mendes (Mestrado)
Universidade de Coimbra, Portugal
2020/10/09 Synthesis and Evaluation of Quinoline-5,8-diones and Isoquinoline-5,8-diones as Anticancer Agents.
Arguente principal
Ryan Kruschel (Doutoramento)
University College Cork, Irlanda
2020/09/24 Inibidores do proteassoma no tratamento do mieloma múltiplo
Arguente principal
Marco Alves (Mestrado)
Universidade de Coimbra, Portugal
2019/03 Utilisation of metabolomics for targeted isolation and production of secondary metabolites in microbial symbionts isolated from extreme environment
Arguente
Bela Sanches (Doutoramento)
University of Strathclyde, Reino Unido
2018/03 Implementing metabolomic tools in the search for new cytotoxic agents from the plant-associated endophytes
Arguente
Yahia Tabaza (Doutoramento)
University of Strathclyde, Reino Unido
2017/10 Member of steering committee for the doctoral thesis - Ralica Arnaudova Ralica Arnaudova (Doutoramento)
Helsingin Yliopisto, Finlândia
2015/09 Potential of cellulose betainates as antimicrobial films
Arguente principal
Lingdai Liu (Mestrado)
Helsingin Yliopisto, Finlândia
2015/05 Synthesis of purpurealidin E derivatives
Arguente
Eero Mäki-Lohiluoma (Mestrado)
Helsingin Yliopisto, Finlândia
2015/01 Member of steering committee for the doctoral thesis - Sofia Montalvão Sofia Montalvão (Doutoramento)
Helsingin Yliopisto, Finlândia
2013/12 Development and syntheses of phosphodiesterase 7 radiotracers for brain imaging
Arguente
Tiina Ahonen (Mestrado)
Helsingin Yliopisto, Finlândia

Comissão de avaliação

Descrição da atividade
Tipo de assessoria
Instituição / Organização Entidade financiadora
2023/06 - Atual REVISOR EXTERNO para o Cyprus Research and Innovation Foundation (RIF)
Avaliador
2021/07 - Atual External reviewer for The Science Fund of the Republic of Serbia
Avaliador
2019/12 - 2019/12 External Reviewer for the BBSRC (UK)
Avaliador
2019/06 - 2019/06 External Reviewer for the Doctoral Programme in Drug Research, University of Eastern Finland
Avaliador
2019/01 - 2019/01 External reviewer for the Slovenian Research Agency (ARRS), Slovenia
Avaliador
2018/12 - 2018/12 External Reviewer for the Independent Research Fund Denmark | Technology and Production
Avaliador
2017/09 - 2017/09 Examination of the Quality of the Research Outputs and Standing of Members of the Staff, South Africa National Research Foundation
Avaliador

Membro de associação

Nome da associação Tipo de participação
2019 - Atual Group for the Promotion of Pharmaceutical chemistry in Academia (GP2A) Member
2011 - Atual European Federation of Medicinal Chemistry (EFMC) Member
2011 - Atual Portuguese Society of Chemistry (SPQ) Member
2003 - Atual American Chemical Society Member
2012 - 2017 Finnish Pharmaceutical Society Member

Membro de comissão

Descrição da atividade
Tipo de participação
Instituição / Organização
2019 - Atual Committee Member for the Group for the Promotion of Pharmaceutical chemistry in Academia (GP2A)
Membro
2018/10 - 2020/08 Elected member of the Faculty of Science Resources and Planning Committee (FRAP)
Membro
University of Strathclyde, Reino Unido
2016/01 - 2018/03 Management Committee Member (representing Finland) - the European Cooperation in Science & Technology (COST) Action CM1307 named “Targeted chemotherapy towards diseases caused by endoparasites“
Membro
Helsingin Yliopisto, Finlândia

Outro júri / avaliação

Descrição da atividade Instituição / Organização
2023/08 - Atual VOGAL DO JÚRI DE RECRUTAMENTO de bolsa de investigação, com a referência IT137-23-311, no âmbito do projeto MiCRoARTiS - Microwave Fingerprinting Artificial Molecular Motors in Virtual Isolation Universidade de Coimbra, Portugal
2023/07 - Atual Júri da disciplina de Seminários II Nuno Campos - "Chiral Tag Rotational Spectroscopy" Doutoramento em Física Atómica e Molecular Universidade de Coimbra, Portugal
2023/02 - Atual VOGAL DO JÚRI DE RECRUTAMENTO de um Junior Researcher, com a referência IT057-23-13543, área disciplinar de Física ou Engenharia Física, no âmbito do projeto MiCRoARTiS: Microwave Fingerprinting Artificial Molecular Motors in Virtual Isolation Universidade de Coimbra, Portugal

Tutoria

Tópico Nome do aluno
2017/05 - 2018/08 Post-Doc mentoring (PROJECT RESICELL) Dr. Xing Wan
2016/09 - 2017/04 Post-Doc mentoring (PROJECT RESICELL) Dr. Leena Keurulainen
Distinções

Prémio

2017 Chancellor´s Research Fellowship
University of Strathclyde, Reino Unido
2003 Sociedade Farmacêutica Lusitana Award

Título

2015 Title of Docent
Helsingin Yliopisto, Finlândia

Outra distinção

2023 Selected for making a video for promotion of the “PHAsFilm” project (INOVC+)
2023 Selected by the weekly newspaper EXPRESSO for an interview within their project "50 women, 50 ideias to change health"
2016 Highlighted as one of the New Talents Europe 2016, EFMC
2015 Selected for the interview step with Starting Grant proposal 2015
European Research Council, Bélgica
2013 Semi-finalist team in OneStart Competition
Oxbridge Ltd, Reino Unido
2012 Doctoral work highlighted in the European "Atomium Culture Chemistry"