Ana Maria Chiorcea Paquim (9715-0DA9-18D8)

Curriculum Vitae

Ana Maria Chiorcea Paquim

- Ana Maria Chiorcea Paquim obtained a PhD degree in Biochemistry, Biochemical Technology, from University of Coimbra in 2003. Currently she is Scientific Researcher at University of Coimbra (2009-present), integrating the Centre for Mechanical Engineering, Materials and Processes (CEMMPRE). - She taught the Analytical Chemistry II Theoretical-Practical Lectures of the Biochemistry and Chemistry BSc Courses (2019-present), General Chemistry Theoretical-Practical Lectures of the Physics Engineering and Biomedical Engineering Integrated MSc Courses (2020-present), the Bioelectrochemistry Practical Lectures of the Biochemistry and Chemistry BSc, MSc in Chemistry and Biochemistry (2019-2020), the AFM practical classes included in the Bioelectrochemistry Lectures of the Chemistry BSc Course and Advanced Methods of Analysis Lectures of the MSc in Chemistry (2011-present), the Chemistry Theoretical-Practical Lectures of the Biology and Geology BSc Courses (2011-2014). She was also involved in the supervision of a large number of postdoc, PhD, MSc and BSc students from University of Coimbra and University of Bucharest. - She published 6 book chapters, 57 articles in international peer review journals and 1 article in a national peer review journal, with a h-index=24 and 1594 citations. Her research was presented in 58 oral and 35 poster presentations in international conferences. - She and participated in 14 national and European R&D projects, 1 as principal investigator and 13 as member collaborator. She was the Principal Investigator of the R&D project Nanostructured human telomeric DNA electrochemical biosensor for screening anticancer drugs, PTDC/SAU-BMA/118531/2010 (FCT, 2012-2015, 99755.00 Euros, Rated Excellent). - She established an important network of international collaborations with research groups from Spain, Germany, Romania, United Kingdom, Russia, Lithuania, Slovakia, Brazil, South Africa, and USA, which resulted in the publication of more than 30 research articles, exchanges of students and numerous scientific visits. - She is Editorial Board Member of Sensors (ISSN 1424-8220; CODEN: SENSC9, CiteScore 5.0, Q1 ranked), member of the International Society of Electrochemistry (ISE), Bioelectrochemistry Society (BES), Sociedade Portuguesa de Química (SPQ), and invited referee to journals from Elsevier, Wiley, Springer, MDPI, RSC, etc . She was member of the organising committee of 2 international conferences. - Ana Maria Chiorcea Paquim is one of the first AFM and STM users in Portugal, with 20 years of experience in Nanoscience, Nanotecnology, Electrochemistry and Biosensor Technology. Her research activities focused on the: (i) development of nanotechnological sensors devices applied to medical diagnosis and treatment, environment monitoring, security and food quality control, (ii) bottom-up self-assembly of molecules (nucleic acids, proteins, lipids, polymeric matrixes, pharmaceutical drugs, metallic, ceramic and composite materials, etc.), controlled by the appropriate choice of immobilisation procedure, (iii) characterization at nanoscale by in situ AFM and STM, combined with electrochemical methods (cyclic, differential pulse and square wave voltammetry, and electrochemical impedance spectroscopy), and enhanced by complementary studies, such as high-performance liquid chromatography, UV-VIS spectrophotometry, quartz crystal microbalance, gel electrophoresis, scanning electron microscopy, (iv) determination in real-time and at single-molecular level of the biomolecules structure and function at electrified solid-liquid interface, and their interaction with drugs, hazard compounds and pollution agents, (v) development, management and collaboration in R&D projects related to Nanotechnology and Biomaterials, inserted in the scientific fields of Nanotechnologies for Improved Quality of Life.

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Identificação

Identificação pessoal

Nome completo: Ana Maria Chiorcea Paquim

Nomes de citação

Chiorcea Paquim, A.M.

Identificadores de autor

Ciência ID: 9715-0DA9-18D8
ORCID iD: 0000-0002-0605-5147
Researcher Id: F-5036-2013
Scopus Author Id: 9040831500

Endereços de correio eletrónico

anachior@ipn.pt (Profissional)

Telefones

Telefone

239700978 (Profissional)

Moradas

Instituto Pedro Nunes. Rua Pedro Nunes, 3030-199, Coimbra, Coimbra, Portugal (Profissional)

Websites

https://www.uc.pt/en/iii/research_centers/CEMMPRE/researchers/Phd_Res/16 (Profissional)

Domínios de atuação

Ciências da Engenharia e Tecnologias - Nanotecnologia
Ciências Exatas - Química - Eletroquímica
Ciências Médicas e da Saúde - Biotecnologia Médica - Biotecnologia Aplicada à Saúde
Ciências Médicas e da Saúde - Biotecnologia Médica - Biomateriais
Ciências da Engenharia e Tecnologias - Nanotecnologia - Nanoprocessos
Ciências Naturais - Ciências Biológicas - Bioquímica
Ciências Naturais - Ciências Biológicas - Biofísica

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão	Peer-review
Português	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)
Romeno	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)
Inglês	Utilizador proficiente (C2)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C1)	Utilizador proficiente (C2)
Francês	Utilizador independente (B2)	Utilizador independente (B2)	Utilizador independente (B1)	Utilizador independente (B1)	Utilizador independente (B1)
Espanhol; Castelhano	Utilizador elementar (A2)	Utilizador independente (B1)	Utilizador elementar (A2)	Utilizador independente (B1)	Utilizador elementar (A2)
Italiano	Utilizador elementar (A1)	Utilizador elementar (A2)	Utilizador elementar (A1)	Utilizador elementar (A2)	Utilizador elementar (A1)

Formação

	Grau	Classificação
2003 Concluído	Biochemistry (Doutoramento) Especialização em Biochemical Technology Universidade de Coimbra Faculdade de Ciencias e Tecnologia, Portugal "Scanning probe microscopy of DNA and other biological molecules adsorbed on the electrodes surfaces" (TESE/DISSERTAÇÃO)	Aprovado com Distinção e Louvor por Unanimidade
1999 Concluído	Biophysics (Master) Universitatea din Bucuresti Facultatea de Fizica, Roménia "Imaging Guanosine by Scanning Probe Microscopy" (TESE/DISSERTAÇÃO)	10.00 (ten). Marks from 1 to 10.
1997 Concluído	Physics (Licence) Universitatea din Bucuresti Facultatea de Fizica, Roménia "Thermoluminescent dosimetry applied on medical radiography" (TESE/DISSERTAÇÃO)	9.58 (nine, 58%) Marks from 1 to 10.

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2018/12/20 - Atual	Investigador Contratado (Investigação)	Universidade de Coimbra, Portugal

2014/06/01 - 2018/12/19	Pós-doutorado (Investigação)	Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal

2009/06/01 - 2014/05/31	Investigador Auxiliar (carreira) (Investigação)	Universidade de Coimbra, Portugal

2006/12/01 - 2009/05/30	Pós-doutorado (Investigação)	Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal

2003/12/01 - 2006/11/30	Pós-doutorado (Investigação)	Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2011/10/01 - 2014/08/31	Professor Auxiliar Convidado (Docente Universitário)	Universidade de Coimbra, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
1999/10/01 - 2003/09/30	Ph.D. Scientific Research, FCT grant PRAXIS XXI/BD/19728/99	Universidade de Coimbra, Portugal

1998/10/01 - 1999/06/30	Scientific Research Activity that led to the elaboration of the M.Sc. Thesis, SOCRATES–ERASMUS fellowship	Universidade de Coimbra, Portugal

1996/11/01 - 1997/07/01	Scientific Research Activity that led to the elaboration of the B.Sc. Thesis	Institutul National de Sanatate Publica, Roménia

Projetos

Projeto

	Designação	Financiadores
2012/03/01 - 2015/08/31	Nanostructured human telomeric DNA electrochemical biosensor for screening anti-cancer drugs PTDC/SAU-BMA/118531/2010 Investigador responsável Fundação para a Ciência e a Tecnologia, Portugal	Fundação para a Ciência e a Tecnologia Concluído
2013/07 - 2015/06	DNA-protein and DNA-cancer cell interactions characterized by AFM and electrochemistry PTDC/QEQ-MED/0586/2012 Investigador	Fundação para a Ciência e a Tecnologia, I.P.
2010/06 - 2013/12	Development, characterization and applications of DNA biosensors PTDC/SAU-BEB/104643/2008 Investigador	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2010/06 - 2013/05	Development of an electrochemical biosensor for sceening of new anti-cancer drugs based on the inhibition of tyrosine kinase enzyme PTDC/SAU-BEB/104643/2008 Investigador	Fundação para a Ciência e a Tecnologia Concluído
2008 - 2012	Self-Assembled Guanosine Structures for Molecular Electronic Devices - European Network on G-Quartets and Quadruplex Nucleic Acids (G4-NET) (Partner) COST Action MP0802 Investigador	European Union Concluído
2009/01 - 2011/12	Novel strategies for electrode surface modification and adsorption: nanoscale characterisation and application to sensor development and corrosion inhibition PTDC/QUI/65732/2006 Investigador	Fundação para a Ciência e a Tecnologia, I.P.
2008/01 - 2010/12	Nanobioelectrochemistry: development, surface characterization and applications of layer by layer nanostrutured DNA- and enzyme-modified electrodes PTDC/QUI/65255/2006 Investigador	Fundação para a Ciência e a Tecnologia, I.P. Concluído
2003 - 2006	DNA-electrochemical biosensors – Surface characterization by scanning probe microscopy (SPM) POCTI/QUI/47201/2002 Investigador	Fundação para a Ciência e a Tecnologia Concluído
2000 - 2003	Evaluation/Validation of novel biosensors in real environmental and food samples QLK3-2000-01311 Investigador	European Union Concluído
2000 - 2003	Biomarker for DNA oxidative lesions POCTI/ESP/33305/2000 Investigador	Fundação para a Ciência e a Tecnologia Concluído
1999 - 2003	On-line electrochemical pathogen alarm based on DNA hybridisation (PATH–ALARM) INCO – Copernicus (ERBICT15CT960804) Investigador	European Union Concluído
1999 - 2001	Development and medical applications of electrochemical DNA-biosensors PRAXIS/C/SAU/93/96 Investigador	Fundação para a Ciência e a Tecnologia Concluído

Outro

	Designação	Financiadores
2020 - 2023	R&D Unit Funding - CEMMPRE UID/EMS/00285/2020 Investigador	Fundação para a Ciência e a Tecnologia, I.P. Em curso
2015 - 2018	Financiamento da Unidade de I&D CEMUC, UID/EMS/00285/2013 UID/EMS/00285/2013 Investigador

Produções

Publicações

Artigo em revista	Chiorcea-Paquim, Ana-Maria. Autor correspondente: Chiorcea-Paquim, Ana-Maria. "8-oxoguanine and 8-oxodeoxyguanosine Biomarkers of Oxidative DNA Damage: A Review on HPLC–ECD Determination". Molecules 27 5 (2022): 1620. http://dx.doi.org/10.3390/molecules27051620. Acesso aberto • Publicado • 10.3390/molecules27051620 Chiorcea-Paquim, Ana-Maria; Oliveira-Brett, Ana Maria. Autor correspondente: Oliveira-Brett, Ana Maria. "Amyloid beta peptides electrochemistry: A review". Current Opinion in Electrochemistry 31 (2022): 100837. http://dx.doi.org/10.1016/j.coelec.2021.100837. Publicado • 10.1016/j.coelec.2021.100837 Chiorcea-Paquim, Ana-Maria; Oliveira-Brett, Ana Maria. "DNA Electrochemical Biosensors for In Situ Probing of Pharmaceutical Drug Oxidative DNA Damage". Sensors 21 4 (2021): 1125. http://dx.doi.org/10.3390/s21041125. Acesso aberto • Publicado • 10.3390/s21041125 Chiorcea-Paquim, Ana-Maria; Oliveira-Brett, Ana Maria. "Nanostructured material–based electrochemical sensing of oxidative DNA damage biomarkers 8-oxoguanine and 8-oxodeoxyguanosine: a comprehensive review". Microchimica Acta 188 2 (2021): 58. http://dx.doi.org/10.1007/s00604-020-04689-7. Publicado • 10.1007/s00604-020-04689-7 Fernandes, Isabel Garrido; Chiorcea-Paquim, A.M.; Oliveira-Brett, Ana Maria. "Calcium channel blocker lercanidipine electrochemistry using a carbon black–modified glassy carbon electrode". Analytical and Bioanalytical Chemistry 412 (2020): 6381-6389. http://dx.doi.org/10.1007/s00216-020-02591-y. No prelo • 10.1007/s00216-020-02591-y Chiorcea Paquim, A.M.; Oliveira-Brett, Ana Maria; Enache, T.A.; Eric de Souza Gil. "Natural phenolic antioxidants electrochemistry: towards a new food science methodology". Comprehensive Reviews in Food Science and Food Safety 19 (2020): 1680-1726. Publicado • 10.1111/1541-4337.12566 Oliveira-Brett, Ana Maria; Diculescu, Victor Constatin; Enache, Teodor Adrian; Fernandes, Isabel P.G.; Chiorcea-Paquim, Ana-Maria; Oliveira, S. Carlos B.. "Bioelectrochemistry for sensing amino acids, peptides, proteins and DNA interactions". Current Opinion in Electrochemistry 14 (2019): 173-179. http://dx.doi.org/10.1016/j.coelec.2019.03.008. Publicado • 10.1016/j.coelec.2019.03.008 Jesus, C.S.H.; Chiorcea Paquim, A.M.; Barsan, M.M.; Diculescu, V.C.. "Electrochemical assay for 20S proteasome activity and inhibition with anti-cancer drugs". Talanta (2019): No prelo • 10.1016/j.talanta.2019.02.052 Chiorcea-Paquim, A.-M.; Enache, T.A.; Oliveira-Brett, A.M.. "Electrochemistry of Alzheimer Disease Amyloid Beta Peptides". Current Medicinal Chemistry 25 33 (2018): 4066-4083. 10.2174/0929867325666180214112536 Enache, T.A.; Chiorcea-Paquim, A.-M.; Oliveira-Brett, A.M.. "Amyloid Beta Peptide VHHQ, KLVFF, and IIGLMVGGVV Domains Involved in Fibrilization: AFM and Electrochemical Characterization". Analytical Chemistry 90 3 (2018): 2285-2292. 10.1021/acs.analchem.7b04686 Chiorcea-Paquim, A.-M.; Eritja, R.; Oliveira-Brett, A.M.. "Electrochemical and AFM Characterization of G-Quadruplex Electrochemical Biosensors and Applications". Journal of Nucleic Acids 2018 (2018): 1-20. http://dx.doi.org/10.1155/2018/5307106. 10.1155/2018/5307106 Jesus, C.S.H.; Chiorcea Paquim, A.-M.; Diculescu, V.C.. "Voltammetric and atomic force microscopy characterization of chymotrypsin, trypsin and caspase activities of proteasome". Catalysis Today 306 (2018): 287-293. 10.1016/j.cattod.2017.01.012 Enache, T.A.; Chiorcea-Paquim, A.-M.; Oliveira-Brett, A.M.. "Amyloid–ß peptides time-dependent structural modifications: AFM and voltammetric characterization". Analytica Chimica Acta 926 (2016): 36-47. 10.1016/j.aca.2016.04.015 Chiorcea-Paquim, A.-M.; Oliveira-Brett, A.M.. "Guanine Quadruplex Electrochemical Aptasensors". Chemosensors 4 3 (2016): 13. 10.3390/chemosensors4030013 Diculescu, V.C.; Chiorcea-Paquim, A.-M.; Oliveira-Brett, A.M.. "Applications of a DNA-electrochemical biosensor". TrAC - Trends in Analytical Chemistry 79 (2016): 23-36. 10.1016/j.trac.2016.01.019 Chiorcea-Paquim, A.-M.; Pontinha, A.D.R.; Eritja, R.; Lucarelli, G.; Sparapani, S.; Neidle, S.; Oliveira-Brett, A.M.. "Atomic Force Microscopy and Voltammetric Investigation of Quadruplex Formation between a Triazole-Acridine Conjugate and Guanine-Containing Repeat DNA Sequences". Analytical Chemistry 87 12 (2015): 6141-6149. 10.1021/acs.analchem.5b00743 Chiorcea-Paquim, A.-M.; Pontinha, A.D.R.; Oliveira-Brett, A.M.. "Quadruplex-targeting anticancer drug BRACO-19 voltammetric and AFM characterization". Electrochimica Acta 174 1 (2015): 155-163. 10.1016/j.electacta.2015.05.146 Chiorcea-Paquim, A.-M.; Diculescu, V.C.; Cervini, P.; Cavalheiro, E.T.G.; Oliveira Brett, A.M.. "Graphite-castor oil polyurethane composite electrode surfaces - AFM morphological and electrochemical characterisation". Journal of Electroanalytical Chemistry 731 (2014): 172-178. 10.1016/j.jelechem.2014.07.027 Rodrigues Pontinha, A.D.; Chiorcea-Paquim, A.-M.; Eritja, R.; Oliveira-Brett, A.M.. "Quadruplex nanostructures of d(TGGGGT): Influence of sodium and potassium ions". Analytical Chemistry 86 12 (2014): 5851-5857. 10.1021/ac500624z Chiorcea-Paquim, A.-M.; Pontinha, A.D.R.; Oliveira-Brett, A.M.. "Time-dependent polyguanylic acid structural modifications". Electrochemistry Communications 45 (2014): 71-74. 10.1016/j.elecom.2014.05.019 Chiorcea-Paquim, A.-M.; Oliveira-Brett, A.M.. "Redox behaviour of G-quadruplexes". Electrochimica Acta 126 (2014): 162-170. 10.1016/j.electacta.2013.07.150 Chiorcea-Paquim, A.-M.; Santos, P.V.; Oliveira-Brett, A.M.. "Atomic force microscopy and voltammetric characterisation of synthetic homo-oligodeoxynucleotides". Electrochimica Acta 110 (2013): 599-607. 10.1016/j.electacta.2013.03.103 Chiorcea-Paquim, A.-M.; Santos, P.V.; Eritja, R.; Oliveira-Brett, A.M.. "Self-assembled G-quadruplex nanostructures: AFM and voltammetric characterization". Physical Chemistry Chemical Physics 15 23 (2013): 9117-9124. 10.1039/c3cp50866h Pontinha, A.D.R.; Jorge, S.M.A.; Chiorcea Paquim, A.-M.; Diculescu, V.C.; Oliveira-Brett, A.M.. "In situ evaluation of anticancer drug methotrexate-DNA interaction using a DNA-electrochemical biosensor and AFM characterization". Physical Chemistry Chemical Physics 13 12 (2011): 5227-5234. 10.1039/c0cp02377a Diculescu, V.C.; Chiorcea-Paquim, A.-M.; Eritja, R.; Oliveira-Brett, A.M.. "Evaluation of the structure-activity relationship of thrombin with thrombin binding aptamers by voltammetry and atomic force microscopy". Journal of Electroanalytical Chemistry 656 1-2 (2011): 159-166. 10.1016/j.jelechem.2010.11.037 Batista, T.; Chiorcea-Paquim, A.-M.; Brett, A.M.O.; Schmitt, C.C.; Neumann, M.G.. "Laponite RD/polystyrenesulfonate nanocomposites obtained by photopolymerization". Applied Clay Science 53 1 (2011): 27-32. 10.1016/j.clay.2011.04.007 Corduneanu, O.; Chiorcea Paquim, A.-M.; Diculescu, V.C.; Fiuza, S.M.; Marques, M.P.M.; Oliveira-Brett, A.M.. "DNA interaction with palladium chelates of biogenic polyamines using atomic force microscopy and voltammetric characterization". Analytical Chemistry 82 4 (2010): 1245-1252. 10.1021/ac902127d Diculescu, V.C.; Chiorcea Paquim, A.-M.; Eritja, R.; Oliveira-Brett, A.M.. "Thrombin-binding aptamer quadruplex formation: AFM and voltammetric characterization". Journal of Nucleic Acids 2010 (2010): 10.4061/2010/841932 Corduneanu, O.; Chiorcea Paquim, A.-M.; Fiuza, S.M.; Marques, M.P.M.; Oliveira-Brett, A.M.. "Polynuclear palladium complexes with biogenic polyamines: AFM and voltammetric characterization". Bioelectrochemistry 78 2 (2010): 97-105. 10.1016/j.bioelechem.2009.08.003 Enache, T.A.; Chiorcea Paquim, A.-M.; Fatibello-Filho, O.; Oliveira-Brett, A.M.. "Hydroxyl radicals electrochemically generated in situ on a boron-doped diamond electrode". Electrochemistry Communications 11 7 (2009): 1342-1345. 10.1016/j.elecom.2009.04.017 Chiorcea Paquim, A.-M.; Corduneanu, O.; Oliveira, S.C.B.; Diculescu, V.C.; Oliveira-Brett, A.M.. "Electrochemical and AFM evaluation of hazard compounds-DNA interaction". Electrochimica Acta 54 7 (2009): 1978-1985. 10.1016/j.electacta.2008.07.032 Diculescu, V.C.; Chiorcea Paquim, A.-M.; Tugulea, L.; Vivan, M.; Oliveira-Brett, A.-M.. "Interaction of imatinib with liposomes: Voltammetric and AFM characterization". Bioelectrochemistry 74 2 (2009): 278-288. 10.1016/j.bioelechem.2008.10.003 Oliveira, S.C.B.; Chiorcea Paquim, A.M.; Ribeiro, S.M.; Melo, A.T.P.; Vivan, M.; Oliveira-Brett, A.M.. "In situ electrochemical and AFM study of thalidomide-DNA interaction". Bioelectrochemistry 76 1-2 (2009): 201-207. 10.1016/j.bioelechem.2009.03.003 Corduneanu, O.; Chiorcea Paquim, A.-M.; Garnett, M.; Oliveira-Brett, A.M.. "Lipoic acid-palladium complex interaction with DNA, voltammetric and AFM characterization". Talanta 77 5 (2009): 1843-1853. 10.1016/j.talanta.2008.10.046 Martinovic, J.; Chiorcea Paquim, A.-M.; Diculescu, V.C.; Van Wyk, J.; Iwuoha, E.; Baker, P.; Mapolie, S.; Oliveira-Brett, A.-M.. "Metallo-functionalized first-generation salicylaldimine poly(propylenimine) tetraamine dendrimers: Electrochemical study and atomic force microscopy imaging". Electrochimica Acta 53 14 (2008): 4907-4919. 10.1016/j.electacta.2008.02.013 Chiorcea Paquim, A.-M.; Pauliukaite, R.; Brett, C.M.A.; Oliveira-Brett, A.M.. "AFM nanometer surface morphological study of in situ electropolymerized neutral red redox mediator oxysilane sol-gel encapsulated glucose oxidase electrochemical biosensors". Biosensors and Bioelectronics 24 2 (2008): 297-305. 10.1016/j.bios.2008.04.001 Corduneanu, O.; Diculescu, V.C.; Chiorcea Paquim, A.-M.; Oliveira-Brett, A.-M.. "Shape-controlled palladium nanowires and nanoparticles electrodeposited on carbon electrodes". Journal of Electroanalytical Chemistry 624 1-2 (2008): 97-108. 10.1016/j.jelechem.2008.07.034 Santos, D.P.; Zanoni, M.V.B.; Bergamini, M.F.; Chiorcea Paquim, A.-M.; Diculescu, V.C.; Oliveira Brett, A.-M.. "Poly(glutamic acid) nanofibre modified glassy carbon electrode: Characterization by atomic force microscopy, voltammetry and electrochemical impedance". Electrochimica Acta 53 11 (2008): 3991-4000. 10.1016/j.electacta.2007.08.072 Diculescu, V.C.; Chiorcea Paquim, A.-M.; Corduneanu, O.; Oliveira-Brett, A.M.. "Palladium nanoparticles and nanowires deposited electrochemically: AFM and electrochemical characterization". Journal of Solid State Electrochemistry 11 7 (2007): 887-898. 10.1007/s10008-007-0275-7 Chiorcea Paquim, A.M.; Piedade, J.A.P.; Wombacher, R.; Jäschke, A.; Oliveira-Brett, A.M.. "Atomic force microscopy and anodic voltammetry characterization of a 49-Mer Diels-Alderase ribozyme". Analytical Chemistry 78 24 (2006): 8256-8264. 10.1021/ac061040+ Chiorcea Paquim, A.-M.; Oretskaya, T.S.; Oliveira Brett, A.M.. "Adsorption of synthetic homo- and hetero-oligodeoxynucleotides onto highly oriented pyrolytic graphite: Atomic force microscopy characterization". Biophysical Chemistry 121 2 (2006): 131-141. 10.1016/j.bpc.2005.12.017 Pauliukaite, R.; Chiorcea Paquim, A.M.; Oliveira Brett, A.M.; Brett, C.M.A.. "Electrochemical, EIS and AFM characterisation of biosensors: Trioxysilane sol-gel encapsulated glucose oxidase with two different redox mediators". Electrochimica Acta 52 1 (2006): 1-8. 10.1016/j.electacta.2006.03.081 Chiorcea Paquim, A.-M.; Oretskaya, T.S.; Oliveira Brett, A.M.. "Atomic force microscopy characterization of synthetic pyrimidinic oligodeoxynucleotides adsorbed onto an HOPG electrode under applied potential". Electrochimica Acta 51 24 (2006): 5037-5045. 10.1016/j.electacta.2006.03.041 Oliveira-Brett, A.M.; Chiorcea Paquim, A.-M.; Diculescu, V.C.; Piedade, J.A.P.. "Electrochemistry of nanoscale DNA surface films on carbon". Medical Engineering and Physics 28 10 (2006): 963-970. 10.1016/j.medengphy.2006.05.009 Diculescu, V.C.; Chiorcea Paquim, A.-M.; Brett, A.M.O.. "Electrochemical DNA sensors for detection of DNA damage". Sensors 5 6-10 (2005): 377-393. Oliveira Brett, A.M.; Chiorcea Paquim, A.-M.. "DNA imaged on a HOPG electrode surface by AFM with controlled potential". Bioelectrochemistry 66 (2005): 117-124. 10.1016/j.bioelechem.2004.05.009 Alves, V.A.; Chiorcea Paquim, A.-M.; Cavaleiro, A.; Brett, C.M.A.. "The nanostructure and microstructure of steels: Electrochemical Tafel behaviour and atomic force microscopy". Corrosion Science 47 12 (2005): 2871-2882. 10.1016/j.corsci.2005.05.038 Oliveira Brett, A.M.; Chiorcea Paquim, A.-M.; Diculescu, V.; Oretskaya, T.S.. "Synthetic oligonucleotides: AFM characterisation and electroanalytical studies". Bioelectrochemistry 67 (2005): 181-190. 10.1016/j.bioelechem.2004.06.008 Chiorcea Paquim, A.M.; Oliveira Brett, A.M.; null. "Microscopia de força atómica de moléculas de DNA adsorvidas na superfície de HOPG". Química – Boletim da Sociedade Portuguesa de Química 94 (2004): 57-68. Chiorcea, A.-M.; Brett, A.M.O.. "Atomic force microscopy characterization of an electrochemical DNA-biosensor". Bioelectrochemistry 63 1-2 (2004): 229-232. 10.1016/j.bioelechem.2003.09.029 Chiorcea Paquim, A.-M.; Diculescu, V.C.; Oretskaya, T.S.; Oliveira Brett, A.M.. "AFM and electroanalytical studies of synthetic oligonucleotide hybridization". Biosensors and Bioelectronics 20 5 (2004): 933-944. 10.1016/j.bios.2004.06.018 Oliveira Brett, A.M.; Chiorcea, A.-M.. "Effect of pH and applied potential on the adsorption of DNA on highly oriented pyrolytic graphite electrodes. Atomic force microscopy surface characterisation". Electrochemistry Communications 5 2 (2003): 178-183. 10.1016/S1388-2481(03)00014-6 Oliveira Brett, A.M.; Chiorcea, A.-M.. "Atomic force microscopy of DNA immobilized onto a highly oriented pyrolytic graphite electrode surface". Langmuir 19 9 (2003): 3830-3839. 10.1021/la027047d Chiorcea, A.-M.; Oliveira-Brett, A.M.. "Scanning probe microscopic imaging of guanine on a highly oriented pyrolytic graphite electrode". Bioelectrochemistry 55 1-2 (2002): 63-65. 10.1016/S1567-5394(01)00168-2 Oliveira-Brett, A.M.; Piedade, J.A.P.; Chiorcea, A.-M.. "Anodic voltammetry and AFM imaging of picomoles of adriamycin adsorbed onto carbon surfaces". Journal of Electroanalytical Chemistry 538-539 (2002): 267-276. 10.1016/S0022-0728(02)00944-0
Capítulo de livro	Severino Carlos Bezerra Oliveira; Diculescu, V.C.; Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Electrochemical Biosensors for DNA–Drug Interactions". In Encyclopedia of Interfacial Chemistry, editado por Wandelt, K., 124-139. Elsevier, 2018. Publicado • 10.1016/b978-0-12-409547-2.13499-7 Chiorcea-Paquim, A.-M.; Oliveira, S.C.B.; Diculescu, V.C.; Oliveira-Brett, A.M.. "Applications of DNA-Electrochemical Biosensors in Cancer Research". In Past, Present and Future Challenges of Biosensors and Bioanalytical Tools in Analytical Chemistry: A Tribute to Professor Marco Mascini, editado por Barcelo, D.; Hansen, P.D.; Palchetti, I., 287-336. Elsevier, 2017. 10.1016/bs.coac.2017.06.003 Chiorcea Paquim, A.-M.; Santos, P.; Diculescu, V.C.; Eritja, R.; Oliveira Brett, A.M.. "Electrochemical Characterization of Guanine Quadruplexes". In Guanine Quartets, editado por Spada, G.P., 100-109. Royal Society of Chemistry, 2013. 10.1039/9781849736954-00100 Oliveira Brett, A.M.; Diculescu, V.C.; Chiorcea-Paquim, A.-M.; Serrano, S.H.P. "Chapter 20 DNA-electrochemical biosensors for investigating DNA damage". In Comprehensive Analytical Chemistry, 413-437. Elsevier, 2007. 10.1016/s0166-526x(06)49020-6 Chiorcea Paquim, A.-M.; Oliveira Brett, A.M.. "Procedure 28 Atomic force microscopy characterization of a DNA electrochemical biosensor". In Comprehensive Analytical Chemistry, editado por Alegret, S., e203-e205. Elsevier, 2007. 10.1016/s0166-526x(06)49071-1 Chiorcea, A.-M.; Oliveira Brett, A.M.. "AFM of guanine adsorbed on HOPG under electrochemical control". In Scanning Probe Microscopy: Characterization, Nanofabrication and Device Application of Functional Materials, editado por Vilarinho, P., 467-473. Países Baixos: Kluwer Academic Publishers, 2005. 10.1007/1-4020-3019-3_28
Poster em conferência	Chiorcea Paquim, A.M.; Fernandes, Isabel Garrido; Oliveira-Brett, Ana Maria. "Electrochemistry of the calcium channel blocker lercanidipine at a carbon black modified glassy carbon electrode". Trabalho apresentado em Analítica 2020, 10º Encontro da Divisão de Química Analítica da SPQ, 2020. Chiorcea Paquim, A.M.; Fernandes, Isabel Garrido; Oliveira-Brett, Ana Maria. "Electrochemistry of the calcium channel blocker lercanidipine at a carbon black modified glassy carbon electrode". Trabalho apresentado em 71st Annual Meeting of the International Society of Electrochemistry, 2020. Chiorcea Paquim, A.M.; Pontinha, A.D.R.; Eritja, R.; Oliveira-Brett, A.M.. "Tetrahymena telomeric repeat sequence d(TG4T) binding with triazole-acridine conjugate GL15". Trabalho apresentado em XXIII International Symposium on Bioelectrochemistry and Bioenergetics, Malmö, Sweden, 2015. Chiorcea Paquim, A.M.; Manaia, M.N.. "Voltammetric characterization of pyrrole, porphine and meso-substituted porphyrins". Trabalho apresentado em International Symposium on Bioelectrochemistry and Bioenergetics, Malmö, Sweden, 2015. Chiorcea Paquim, A.M.; Pontinha, A.D.R.; Eritja, R.; Oliveira-Brett, A.M.. "G-rich DNA Quadruplex Nanostructures: Influence of Sodium and Potassium Ions". Trabalho apresentado em 65th Annual Meeting of the International Society of Electrochemistry, Lausanne, Switzerland, 2014. Pontinha, A.D.R.; Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Time-dependent polyguanylic acid structural modifications characterization by atomic force microscopy and voltammetry". Trabalho apresentado em Symposium of the Analytical Division of SPQ-Analítica-2014, Coimbra, Portugal, 2014. Chiorcea Paquim, A.M.; Pontinha, A.D.R.; Oliveira-Brett, A.M.. "Atomic force microscopy and voltammetric characterization of d(TG4T)". Trabalho apresentado em Symposium of the Analytical Division of SPQ-Analítica-2014, Coimbra, Portugal, 2014. Chiorcea Paquim, A.M.; Santos, P.V.; Oliveira-Brett, A.M.. "Atomic Force Microscopy and Voltammetric Characterization of Homo-Oligodeoxynucleotides". Trabalho apresentado em Biochemistry 2013, 12th Topical Meeting of the International Society of Electrochemistry and XXII International Symposium on Bioelectrochemistry and Bioenergetics of the Bioelectrochemical Society, Bochum, Germany, 2013. Chiorcea Paquim, A.M.; Santos, P.V.; Oliveira-Brett, A.M.. "Effect of pH and secondary structure on the adsorption and voltammetric behaviour of guanine-containing Oligodeoxynucleotides". Trabalho apresentado em Third Regional Symposium on Electrochemistry South-East Europe (RSE–SEE3), Bucharest, Romania, 2012. Diculescu, V.C.; Chiorcea Paquim, A.M.; Corduneanu, O.; Fiuza, S.M.; Oliveira-Brett, A.M.. "DNA Interaction with Palladium Chelates of Biogenic Polyamines – AFM and Voltammetric Characterization". Trabalho apresentado em The 61st Annual Meeting of the International Society of Electrochemistry - ISE 2010, Nice, France, 2010. Pontinha, A.D.R.; Diculescu, V.C.; Jorge, S.M.A.; Vivan, M.; Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Voltammetric and AFM Study of Methotrexate-DNA Interaction". Trabalho apresentado em The 61st Annual Meeting of the International Society of Electrochemistry - ISE 2010, Nice, France, 2010. Diculescu, V.C.; Chiorcea Paquim, A.M.; Santos, D.P.; Oliveira-Brett, A.M.. "Electrochemistry and AFM studies of DNA and Guanine-rich oligomers structural modifications". Trabalho apresentado em Training School on Fundamentals of guanosine self-assembly and quadruplex formation, Ischia, Italy, 2009. Chiorcea Paquim, A.M.; Diculescu, V.C.; Tugulea, L.; Oliveira-Brett, A.M.. "Atomic force microscopy characterization of imatinib-liposomes interactions". Trabalho apresentado em Journées d’Electrochimie, Sinaia, Romania, 2009. Chiorcea Paquim, A.M.; Oretskaya, T.S.; Oliveira-Brett, A.M.. "Effect of pH on the adsorption of synthetic oligonucleotides onto highly oriented pyrolytic graphite electrode". Trabalho apresentado em International Spring School of Biophysics & Bioelectrochemistry for Medicine, Cisnadioara, Romania, 2009. Corduneanu, O.; Chiorcea Paquim, A.M.; Garnett, M.; Oliveira-Brett, A.M.. "Lipoic acid – palladium complexes adsorbed on carbon electrode surfaces. Voltammetric and AFM study". Trabalho apresentado em The 59th Annual Meeting of the International Society of Electrochemistry, Seville, Spain, 2008. Chiorcea Paquim, A.M.; Corduneanu, O.; Diculescu, V.C.; Oliveira-Brett, A.M.. "Atomic force microscopy and voltammetric characterization of lipoic acid – palladium complexes adsorbed on carbon electrode surfaces". Trabalho apresentado em Seeing at the Nanoscale VI – Exploring the Future of Nanotechnology Using SPM and Related Techniques, Berlin, Germany, 2008. Corduneanu, O.; Chiorcea Paquim, A.M.; Diculescu, V.C.; Oliveira-Brett, A.M.. "Characterization of electrodeposited palladium nanoparticles and nanowires on carbon electrodes". Trabalho apresentado em ESEAC–2008. 12th International Conference on Electroanalysis, Prague, Czech Republic. Best poster Award, 3rd place, 2008. Diculescu, V.C.; Chiorcea Paquim, A.M.; Corduneanu, O.; Oliveira-Brett, A.M.. "Electrochemical behaviour of palladium nanoparticles deposited onto carbon surfaces". Trabalho apresentado em 1st Regional Sumposium on Electrochemistry on South – East Europe, Rovinj, Croatia, 2008. Chiorcea Paquim, A.M.; Corduneanu, O.; Diculescu, V.C.; Oliveira-Brett, A.M.. "Atomic force microscopy and electrochemical studies of palladium nanoparticles and nanowires electrodeposited onto carbon electrode surfaces". Trabalho apresentado em NanoSpain2008, Braga, Portugal, 2008. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "AFM characterization of nucleic acid nanofilms on charged surfaces". Trabalho apresentado em XIXth International Symposium on Bioelectrochemistry and Bioenergetics, Toulouse, France, 2007. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "AFM characterization of DNA–biosensor nanofilms adsorbed onto charged surfaces,". Trabalho apresentado em AFM BioMed Conference – International Meeting on AFM in Life Sciences and Medicine, Barcelona, Spain, 2007. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "AFM characterization of synthetic homo and hetero–oligonucleotides adsorbed onto HOPG". Trabalho apresentado em Linz Winter Workshop, Linz, Austria, 2007. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Effect of applied potential on the adsorption of synthetic pyrimidinic oligonucleotides onto HOPG electrode". Trabalho apresentado em Second International Workshop on Biosensors for Food Safety and Environmental Monitoring, Agadir, Morocco, 2005. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Electroanalysis of natural and synthetic polynucleotides". Trabalho apresentado em SPQ–Analítica’05, 5º Encontro da Divisão de Química Analítica da SPQ, Coimbra, Portugal, 2005. Chiorcea Paquim, A.M.; Oretskaya, T.S.; Oliveira-Brett, A.M.. "Atomic force microscopy characterization of synthetic poly– and oligo–homonucleotides adsorbed onto HOPG". Trabalho apresentado em XVIII International Symposium on Bioelectrochemistry and Bioenergetics of the Bioelectrochemical Society (BES) and 3rd Spring Meeting of the International Society of Electrochemistry (ISE), Coimbra, Portugal, 2005. Diculescu, V.C.; Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Electrochemical analysis of natural and synthetic polynucleotides". Trabalho apresentado em XVIII International Symposium on Bioelectrochemistry and Bioenergetics of the Bioelectrochemical Society (BES) and 3rd Spring Meeting of the International Society of Electrochemistry (ISE, Coimbra, Portugal), 2005. Chiorcea Paquim, A.M.; Piedade, J.A.P.; Wombacher, R.; Jäschke, A.; Oliveira-Brett, A.M.. "Atomic force microscopy and anodic voltammetry characterization of 49–mer Diels–Alderase ribozymes". Trabalho apresentado em XVIII International Symposium on Bioelectrochemistry and Bioenergetics of the Bioelectrochemical Society (BES) and 3rd Spring Meeting of the International Society of Electrochemistry (ISE), Coimbra, Portugal, 2005. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Effect of sequence and applied potential on the adsorption of nucleic acids molecules on HOPG electrodes. AFM surface characterization". Trabalho apresentado em International Society of Electrochemistry, 55th Annual Meeting, Thessaloniki, Greece, 2004. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Imaging synthetic oligonucleotides and homopolymer nucleic acids by atomic force microscopy". Trabalho apresentado em EMBO/FEBS Workshop on AFM Applications in Biology, Instituto Gulbenkian de Ciência, Oeiras, Portugal, 2004. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Atomic force microscopy characterization of synthetic oligonucleotides adsorbed onto highly oriented pyrolytic graphite". Trabalho apresentado em Life Sciences Interface Spring School, Nottingham, UK, 2004. Chiorcea Paquim, A.M.; Oliveira Brett, A.M.. "Atomic force microscopy characterization of synthetic oligonucleotides adsorbed onto highly oriented pyrolytic graphite". Trabalho apresentado em UK SPM 2004, A Royal Microscopical Society Meeting, Nottingham, UK, 2004. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Effect of pH and applied potential on the adsorption of DNA on highly oriented pyrolytic graphite electrodes". Trabalho apresentado em XVIIth International Symposium on Bioelectrochemistry and Bioenergetics, Florence, Italy, 2003. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "AFM of guanine adsorbed on HOPG under electrochemical control". Trabalho apresentado em NATO Advanced Study Institute, Scanning Probe Microscopy: Characterization, Nanofabrication and Device Application of Functional Materials, Albufeira, Portugal, 2002. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Electrochemical atomic force microscopy of adriamycin adsorbed on a highly oriented pyrolytic graphite electrode surface". Trabalho apresentado em 53rd Annual Meeting of the International Society of Electrochemistry, Düsseldorf, Germany, 2002. Chiorcea Paquim, A.M.; Oliveira-Brett, A.M.. "Scanning probe microscopic imaging of guanine on a highly oriented pyrolytic graphite electrode". Trabalho apresentado em XVIth International Symposium on Bioelectrochemistry and Bioenergetics, Bratislava, Slovak Republic, 2001.
Tese / Dissertação	Chiorcea Paquim, A.M.. "Scanning probe microscopy of DNA and other biological molecules adsorbed on the electrodes surfaces". Doutoramento, Universidade de Coimbra, 2003. Chiorcea Paquim, A.M.. "Imaging guanosine by scanning probe microscopy". Mestrado, Universitatea din Bucuresti Facultatea de Fizica, 1999. Chiorcea Paquim, A.M.. "Thermoluminescent dosimetry applied on medical radiography". Licenciatura, Universitatea din Bucuresti Facultatea de Fizica, 1997.

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2021/05	Calcium channel blocker lercanidipine electrochemistry at a carbon black modified glassy carbon electrode	XXVIth International Symposium on Bioelectrochemistry and Bioenergetics of the Bioelectrochemical Society on Bioelectrochemistry for improved Life Quality Bioelectrochemical Society (Cluj-Napoca, Roménia)
2019/09/09	Voltammetric and atomic force microscopy of amyloid beta peptides	XXI Mendeleev Congress on General an Applied Chemistry (Saint Petersburg, Rússia)
2019/07/07	Electrochemistry of Alzhaimer disease amyloid beta peptides	47th IUPAC World Chemistry Congress and the 50th General Assembly (Paris, França)
2019/05/26	Amyloid beta peptides time-dependent structural modifications: AFM and voltammetric characterization	XXV International Symposium on Bioelectrochemistry and Bioenergetics (Limerick, Irlanda)
2018/06	Agregação e fibrilação dos péptidos beta amilóide da doença de Alzheimer: Caracterização por AFM e eletroquímica	XXIII Congresso de la Sociedad Iberoamericana de Electroquímica SIBAE 2018 (Cuscu, Peru)
2018/05	Protein-DNA interactions and protein electrochemical oxidation	23rd Topical Meeting of the International Society of Electrochemistry (Vilnius, Lituânia)
2017/10	In situ sensing of immunotherapeutic drug at a DNA-nanostructured electrochemical biosensor	Eighth International Workshop on biosensors for food safety and environmental monitoring (Rabat, Marrocos)
2017/08	Electrochemistry of Alzheimer’s disease amyloid beta peptides	68th Annual Meeting of the International Society of Electrochemistry (Providence, Rhode Island, Estados Unidos)
2017/07	Amyloid Beta Peptides Structural Modifications: AFM and Voltammetric Characterization	IUPAC 2017 – 46th World Chemistry Congress and 40ª Reunião Anual da Sociedade Brasileira de Química (São Paulo, Brasil)
2016/10	Electrochemical biosensors for DNA-drug interactions	First Workshop on Electrochemistry Devices – (Bio)Sensors IEEE (Porto, Portugal)
2016/10	Alzheimer’s Disease Amyloid Beta Peptides: AFM and Voltammetric Characterization	PRIME – Pacific Rim Meeting on Electrochemical and Solid State Science 2016 (Honolulu, Hawaii, Estados Unidos)
2016/08	Alzheimer’s disease amyloid beta peptides in vitro oxidation and time-dependent structural modifications: AFM and voltammetric characterization	67th Annual Meeting of the International Society of Electrochemistry (Hague, Países Baixos)
2016/06	Electroanalytical detection of telomeric G-quadruplexes and their application in nanomedicine cancer treatment	SPQ – Analítica 2016 (Lisbon, Portugal)
2016/05	Protein-DNA interaction and protein electrochemical oxidation for bioelectroanalysis of pharmaceuticals	ACSD 2016 – The Third International Symposium on Analytical Chemistry for Sustainable Development (Marrakech, Marrocos)
2016/02	Quadruplex formation between a triazole-acridine conjugate and guanine-containing repeat DNA sequences. Atomic force microscopy and voltammetric characterization	nanoPT 2016 International Conference (Braga, Portugal)
2015/10	Amyloid ß Peptides Nanostructures: Voltammetric and Atomic Force Microscopy Characterization	The 66th Annual Meeting of the International Society of Electrochemistry, Green Electrochemistry for Tomorrow’s Society (Taipei, Taiwan)
2013/08	Effect Of Na+ and K+ ions on G-Quadruplex nanostructures structural conformations,	44th World Chemistry congress of IUPAC (Istambul, Turquia)
2013/06	DNA-electrochemical biosensors for investigating DNA damage based on structural changes	Summer School on Electrochemistry for environmental and medical applications (Cluj-Napoca)
2013/05	In situ sensing of DNA oxidative damage with DNA-nanostructured electrochemical biosensors	FASC, The Second International Symposium on “Analytical Chemistry for Sustainable Development” – ACSD 2013 – The 4th Federation of African Societies of Chemistry (FASC) Congress (Marrakech, Marrocos)
2013/01	Self-assembled G-quadruplex nanowires: AFM and electrochemical characterisation	Fifth ISEAC Triennial International Conference on Advances and Recent Trends in Electrochemistry, (Ramoji Film City, Hyderabad, Índia)
2012/11	DNA-electrochemical biosensors for the detection of specific interactions and oxidative damage to DNA	Simposio Chileno de Electroquímica da sociedade Chilena de Química, División de Electroquímica (Olmué, V Región Valparaíso, Chile)
2012/08	Atomic force microscopy and voltammetric characterisation of quadruplex formation in guanine-containing oligodeoxynucleotides	63rd Annual Meeting of the International Society of Electrochemistry (Prague, República Checa)
2011/11	Quadruplex formation of guanine containing oligodeoxynucleotides: voltammetric and AFM characterization	Third International Meeting on G-quadruplexes and G-assembly (Sorrento, Itália)
2010/11	Guanosine-quadruplex Structures in Thrombine Binding Aptamer - AFM and Voltammetric Characterization	The 61st Annual Meeting of the International Society of Electrochemistry - ISE 2010 (Nice, França)
2010/07	Estudo voltamétrico da interacção com DNA e incorporação em liposomas de derivados fenilaminopirimidinicos com propriedades anticancerígenas	Congreso da Sociedad Iberoamericana de Electroquímica (SIBAE) (Alcalá de Henares, Espanha)
2010/06	In situ electrochemical evaluation of methotrexate-DNA damage	13th International Conference on Electroanalysis, ESEAC (Gijon, Espanha)
2009/08	Electrodeposition of palladium nanoparticles and nanowires onto carbon substrates	International Symposium on Electrochemistry for Energy Conversion and Storage (ISEECS) (Wuhan-Three Gorges, China)
2009/08	DNA-Nanoscale Electrochemical Biosensor: AFM Characterization and Applications	60th Annual Meeting of the International Society of Electrochemistry (ISE) (Beijing, China)
2009/08	In situ sensing of DNA damage with a nanoscale DNA-electrochemical biosensor	12th International Symposium on Electroanalytical Chemistry (12th ISEC) (Changchun, China)
2009/06	Electrochemical atomic force microscopy characterisation of guanosine and guanine self-assemblies onto a HOPG electrode surface	ESF Research Conference on Self-Assembly of Guanosine Derivatives: From Biological Systems to Nanotechnological Applications (Obergurgl, Áustria)
2009/05	Interaction of DNA with palladium and palladium containing compounds. Atomic force microscopy characterization	XXth Symposium of the International Society of Bioelectrochemistry (BES 2009) (Sibiu, Roménia)
2009/05	Voltammetric study of in situ DNA oxidative damage and interaction with liposomes of the antileukemia drug imatinib	XXth Symposium of the International Society of Bioelectrochemistry (BES 2009) (sibiu, Roménia)
2008/09	Palladium nanoparticles and nanowires electrodeposited onto carbon electrodes: AFM and electrochemical studies	The 59th Annual Meeting of the International Society of Electrochemistry (Seville, Espanha)
2008/03	In situ evaluation of hazard compounds–DNA interactions using na electrochemical DNA–biosensor	6th Spring Meeting of the International Society of Electrochemistry (Foz do Iguaçu, Brasil)
2008/03	Nanobioelectroquímica: Caracterização de eléctrodos modificados e aplicações	XVIII Congreso de la Sociedad Iberoamericana de Electroquímica (Medellin, Colômbia)
2007/09	Electrochemistry for probing in situ DNA damage	58th Annual Meeting of the International Society of Electrochemistry (Banff, Canadá)
2007/05	In situ sensing of DNA damage using a nanoscale film DNA–electrochemical biosensor	First Iberic Meeting on Medical Chemistry Anticancer Agents (Régua, Portugal)
2006/12	DNA–electrochemical nanoscale biosensor films: AFM characterization and applications	Química Sustentável, Um Tema. Uma Reflexão, XX Encontro Nacional Sociedade Portuguesa de Química Campus de Caparica – FCTIUNL (Lisbon, Portugal)
2006/09	Atomic microscopy characterization of nucleic acids nanofilms adsorbed onto HOPG electrode surfaces	57th Annual Meeting of the International Society of Electrochemistry (Edinburgh, Reino Unido)
2005/09	AFM characterization of DNA–electrochemical nanoscale biosensor films on carbon electrode surfaces	The 56th Annual Meeting of the International Society of Electrochemistry (Bussan, Coreia do Sul)
2005/09	Influence of steel nanostructure on electrochemical corrosion resistance	The Europeen Corrosion Congress (Lisbon, Portugal)
2005/08	DNA–electrochemical nanoscale biosensor films on carbon electrode surfaces: AFM characterization and applications	40th IUPAC Congress (Beijing, China)
2005/06	AFM characterization of DNA nanoscale biosensor films prepared under applied potential	XVIII International Symposium on Bioelectrochemistry and Bioenergetics of the Bioelectrochemical Society (BES) and 3rd Spring Meeting of the International Society of Electrochemistry (ISE) (Coimbra, Portugal)
2004/09	AFM characterization of synthetic nucleotides and homopolymer nucleic acids adsorbed onto HOPG	International Society of Electrochemistry, 55th Annual Meeting (Thessaloniki, Grécia)
2004/07	AFM characterization and applications of electrochemical DNA–biosensors	International Conference on Electrified Interfaces, 10th in a Series on Non–Traditional Methods (Spa, Bélgica)
2004/05	AFM characterisation and electroanalytical studies of synthetic oligonucleotides	The Eighth World Congress on Biosensors (Granada, Espanha)
2003/11	Atomic force microscopy of DNA immobilized onto a highly oriented pyrolytic graphite electrode surface	SMCBS International Workshop on Surface Modification for Chemical and Biochemical Sensing (Bialowieza, Polónia)
2003/11	Electrochemical DNA–biosensors. Surface AFM characterization and applications	54th Annual Meeting of the International Society of Electrochemistry (São Pedro, Brasil)
2003/10	Synthetic oligonucleotides: AFM characterization and electroanalytical studies	Workshop on “New Trends in Nucleic Acids Based Biosensors” (Florence, Itália)
2003/10	Applications of an electrochemical DNA biosensor	International Workshop on “Biosensors for Food Safety and Environmental Monitoring” (Marrakech, Marrocos)
2003/06	Atomic force microscopy characterisation of an electrochemical DNA–biosensor	XVIIth International Symposium on Bioelectrochemistry and Bioenergetics (Florence, Itália)
2002/11	Analysing structure–function relationship with electrochemical DNA–biosensors	53rd Annual Meeting of the International Society of Electrochemistry (Düsseldorf, Alemanha)
2002/11	Biossensor electroquímico com DNA	XV Congresso da Sociedade Ibero–Americana de Electroquímica (Evora, Portugal)
2002/04	An electrochemical atomic force microscopy study of DNA adsorbed on a highly oriented pyrolytic graphite electrode surface	2nd Workshop of the Concerted Action. “Evaluation / Validation of Novel Biosensors in Real Environmental and Food Samples”, IEEE (Florence, Itália)
2001/10	Biossensor electroquímico de DNA	5as Jornadas do Instituto de Ciência e Engenharia de Materiais e Superfícies (ICEMS) (Coimbra, Portugal)
2001/04	Scanning probe microscopy of adriamycin on highly oriented pyrolytic graphite	10º Encontro da Sociedade Portuguesa de Materiais (SPM), Materiais’ 2001, 1st International Materials Symposium (Coimbra, Portugal)
2000/03	Scanning probe microscopy of guanosine on gold electrode	In Situ Nano Biochemistry – 2000 Workshop, The Royal Danish Academy of Sciences and Letters (Copenhagen, Dinamarca)
1999/10	Imaging guanosine by scanning probe microscopy	5th Workshop “Biosensors for Direct Monitoring of Environmental Pollutants in the Field (Otrokovice, República Checa)

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2022 - 2022	Estudo do comportamento redox de compostos antioxidantes Orientador	Engenharia Biomédica (Licenciatura/Bacharelato) Instituto Politécnico de Coimbra Instituto Superior de Engenharia de Coimbra, Portugal
2013 - 2015	Research Fellow supervised within the R&D project Nanostructured human telomeric DNA electrochemical biosensor for screening anti-cancer drugs - PTDC/SAU-BMA/118531/2010, FCT. Publications: 2 articles submitted, 2 articles in preparation. Orientador	Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2012 - 2015	Post-doctoral researcher in the R&D project Nanostructured human telomeric DNA electrochemical biosensor for screening anti-cancer drugs – PTDC/SAU-BMA/118531/2010. Publications: 2 articles. Orientador	Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2012 - 2015	Post-doctoral researcher in the R&D project Nanostructured human telomeric DNA electrochemical biosensor for screening anti-cancer drugs – PTDC/SAU-BMA/118531/2010 Publications: 1 article. Orientador	Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal
2012 - 2013	Ph.D. student supervised within the R&D project Nanostructured human telomeric DNA electrochemical biosensor for screening anti-cancer drugs – PTDC/SAU-BMA/118531/2010. Orientador	Associação para a Inovação e Desenvolvimento em Ciência e Tecnologia, Portugal

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2014/04/14 - 2014/04/15	Member of the Organizing Committee of the Symposium of the Analytical Division of SPQ-Analítica-2014, 14-15 April 2014, Coimbra, Portugal (2014/04/14 - 2014/04/15) Conferência (Membro da Comissão Organizadora)	Sociedade Portuguesa de Química (SPQ), Portugal Universidade de Coimbra, Portugal
2005/06 - 2005/06	Member of the Organizing Committee of XVIII International Symposium on Bioelectrochemistry and Bioenergetics of the Bioelectrochemical Society (BES) and 3rd Spring Meeting of the International Society of Electrochemistry (ISE). (2005/06/19 - 2005/06/24) Congresso (Membro da Comissão Organizadora)	Universidade de Coimbra, Portugal

Participação em evento

	Descrição da atividade Tipo de evento	Nome do evento Instituição / Organização
2010/01 - 2010/01	Scientific training in the international research group of Institute for Research in Biomedicine, Barcelona, Spain. Outro	Institut de Recerca Biomèdica, Espanha
2006/12 - 2006/12	Scientific training in the international research group of Laboratory of Biophysics, Faculty of Physics, University of Bucharest, Bucharest, Romania. Outro	Universitatea din Bucuresti Facultatea de Fizica, Roménia
2005/11 - 2005/11	Scientific training in the international research group of Laboratory of Biophysics, Faculty of Physics, University of Bucharest, Bucharest, Romania. Outro	Universitatea din Bucuresti Facultatea de Fizica, Roménia
2001/07 - 2001/07	Scientific training in the international research group of European Office of Molecular Imaging Corporation, Witec GmbH, Ulm, Germany. Outro	European Office of Molecular Imaging Corporation, Witec GmbH, Alemanha
2001/02 - 2001/02	Scientific training in the international research group of Laboratory of Electrochemistry, University of Bern, Bern, Switzerland. Outro	Fernfachhochschule Schweiz Regionalzentrum Bern, Suiça
2000/02 - 2000/03	Scientific training in the international research group of Laboratory of Biophysics, Faculty of Mathematics, Physics and Informatics, Comenius University, Bratislava, Slovakia. Outro	Univerzita Komenského v Bratislave, Eslováquia

Júri de grau académico

	Tema Tipo de participação	Nome do candidato (Tipo de grau) Instituição / Organização
2013/07	Estudo eletroquímico do ferrocianeto de potássio (K4[Fe(CN)6].3H2O) Arguente	Edilzo Andrade Silva Filho (Outro) Universidade de Coimbra, Portugal

Arbitragem científica em conferência

	Nome da conferência	Local da conferência
2014/04/14 - 2014/04/15	Symposium of the Analytical Division of SPQ	Coimbra, Portugal

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2002 - Atual	Practical lectures on atomic force microscopy (AFM) included in the Bioelectrochemistry Course, 3rd year of the Chemistry Course, Department of Chemistry.	(Licenciatura)	Universidade de Coimbra, Portugal
2002 - Atual	Practical lectures on atomic force microscopy (AFM) included in the Advanced Methods of Analysis Course, MSc. in Chemistry, Department of Chemistry.	(Mestrado)	Universidade de Coimbra, Portugal
2020 - 2022	Chemistry	Química Geral (Mestrado integrado)	Universidade de Coimbra, Portugal
2020 - 2022	Analytical Chemistry II	Química Analítica II (Licenciatura)	Universidade de Coimbra Departamento de Química, Portugal Universidade de Coimbra Departamento de Ciências da Vida, Portugal
2020 - 2022	Chemistry	Química Geral (Mestrado integrado)	Universidade de Coimbra, Portugal
2019 - 2020	Bioelectrochemistry	Bioquímica (Mestrado integrado)	Universidade de Coimbra, Portugal Universidade de Coimbra Departamento de Química, Portugal
2019 - 2020	Analytical Chemistry	Química Analítica II (Licenciatura)	Universidade de Coimbra Departamento de Química, Portugal
2013 - 2014	Chemistry I Theoretical-Practical Lecture Course, 1st year of Geology B.Sc. Course	(Licenciatura)	Universidade de Coimbra, Portugal
2011 - 2014	Chemistry Theoretical-Practical Lectures, 1st year of Biology B.Sc. Course	(Licenciatura)	Universidade de Coimbra, Portugal

Membro de associação

	Nome da associação	Tipo de participação
2017 - Atual	Sociedade Portuguesa de Química (SPQ)
2013 - Atual	International Society of Electrochemistry (ISE)
2013 - Atual	Bioelectrochemistry Society (BES)

Membro de comissão

	Descrição da atividade Tipo de participação	Instituição / Organização
2021/03/01 - Atual	Editorial Board Member of Sensors (ISSN 1424-8220; CODEN: SENSC9), published by MDPI. CiteScore (2019 Scopus data): 5.0 - ranked 17/129 (Q1) in 'Physics and Astronomy: Instrumentation' and 147/670 (Q1) in 'Electrical and Electronic Engineering' and 70/300 (Q1) in 'Computer Science: Information Systems'. Membro	Sensors (ISSN 1424-8220; CODEN: SENSC9), Suiça

Outro júri / avaliação

	Descrição da atividade	Instituição / Organização
2013 - 2013	Supplemental Member of the PhD Board of Examiners Ph.D. Student: Elena Bernalte Morgado Ph.D. Thesis: Desarrollo y Aplicabilidad de Metodologías Analíticas para la Evaluacíon de Contaminantes Ambientales de Especial Peligrosidad: Hidrocarburos Aromáticos policíclicos y Mercurio	Universidad de Extremadura, Espanha

Tutoria

	Tópico	Nome do aluno
2018 - 2019	Electrochemical characterisation of amyloid beta peptides	Wesley Bruno da Silva Machini
2017 - 2017	Mecanismos eletroquímicos de derivados da isatina e de proteínas membranares calmodulina e caveolinas	Isabel Patrícia Garrido Fernandes
2017 - 2017	Voltammetric study of potassium ferricyanide redox behavior at different electrode materials	Lígia Ferreira Carreira
2012 - 2013	Atomic force microscopy characterisation of G-quadruplex nanostructures	Ana Dora Rodrigues Pontinha
2012 - 2013	Self-assembled G-quadruplex nanostructures characterization	Paulina Viegas Santos
2011 - 2011	Atomic force microscopy characterisation of DNA interaction with methotrexate	Ana Dora Rodrigues Pontinha
2007 - 2010	Atomic force microscopy characterisation of palladium nanowires and nanoparticles, and polynuclear palladium complexes with biogenic polyamines and their interaction with DNA	Oana Corduneanu
2009 - 2009	Hydroxyl radicals electrochemically generated in situ on a boron-doped diamond electrode	Adrian Teodor Enache
2008 - 2009	Atomic force microscopy characterisation of DNA interaction with hazard compounds and thalidomine	Severino Carlos Bezerra de Oliveira
2008 - 2008	Atomic force microscopy characterisation of carbon electrodes	Carla Isabel Madaleno Gouveia Branco Caridade
2007 - 2007	Atomic force microscopy characterisation of metallo–functionalized first–generation salicylaldimine poly(propylenimine) tetraamine dendrimers	Jasmina Martinovic
2007 - 2007	Atomic force microscopy characterisation of Poly(glutamic acid) nanofibre modified glassy carbon electrodes	Daniela Pereira dos Santos
2000 - 2000	Atomic force microscopy characterisation of steel nanostructures on electrochemical corrosion resistance	Valeria Alves
1999 - 2000	Atomic force microscopy of biomaterias	Ana Paula Fonseca Piedade