IVO CRISTIANO DA ROCHA MARTINS (8C17-BB8B-E8DB)

Curriculum Vitae

IVO CRISTIANO DA ROCHA MARTINS

I graduated in Microbiology in 2002 at UCP, Porto, PT (1st of 46 students), joining Serrano lab, EMBL, Heidelberg, Germany, in 2003. There I met my PhD supervisors, Frederic Rousseau & Joost Schymkowitz, Switch Lab, VIB, VUB, Brussels, BE ¿ now at VIB, Catholic University of Leuven (KUL), Leuven, BE. My PhD in Bioengineering ¿ Biophysics, funded by BIF (2004-2006) & FCT (2006-2009), led to 3 articles and a patented fibril disassembly method. The PhD defence (2009/02/23) on amyloid fibrils stability was awarded a ¿Greatest Distinction¿ grade (maximum). My post-doc (2009-2013) on dengue virus capsid protein biophysics was funded by FCT and a prestigious Marie Curie EU grant and done between Portugal and Brazil. It led to the Gulbenkian Frontiers Research Prize in 2010, given the good results: 7 articles, 3 awards to me (2 to my students), >20 media articles and a patented dengue inhibitor. In 2014 I started an independent position, working on protein-ligand interactions at iMM, Lisbon, PT. I obtained funding, supervised students and purchased equipment. This led to 3 new international collaborations, >20 top publications (>10 as senior author) and a Hans Neurath Outstanding Promise Award in 2015 (becoming a Protein Society Honorary Member). I also promoted my team, with my students giving >30 oral presentations and receiving >10 prizes themselves. In 2016, with two PhD students, I was selected for the COHiTEC Program, focused on translating lab data into business, via a technology conceived by me to beat current disease detection limits. We won the program, with a business plan centred on monetizing the technology. Then, in 2017, I co-founded DART Diagnostics, with venture capital funding (Caixa Capital). In 2018, DART Diagnostics was awarded an European H2020 SME Instruments Phase I Funding (top 2% of applications), to use DART technology for early pathogen detection (patented in February 2020, definitive paten in February 2021). In 2020/2021, I led a 488k EUR consortium of four institutions, funded by P2020, to apply DART technology for SARS-CoV-2/COVID-19 early detection. Given all my experience, skills and know-how I was also invited in 2019 to teach medical biochemistry to medical doctor students at FMUL, being since then assistant professor at FMUL. I am alos currently leading an exploratory project, funded by FCT, to develop dengue inhibitors. Overall, I have over 3300 citations at Google Scholar (https://scholar.google.com/citations?user=VCMp9iEAAAAJ&hl=en). Scopus h-index: 18, Scopus citations: 2396.

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Identificação

Identificação pessoal

Nome completo: IVO CRISTIANO DA ROCHA MARTINS

Nomes de citação

Martins, Ivo C.

Identificadores de autor

Ciência ID: 8C17-BB8B-E8DB
ORCID iD: 0000-0002-9284-8599
Google Scholar ID: https://scholar.google.pt/citations?user=VCMp9iEAAAAJ&hl=en&oi=ao

Moradas

DART Diagnostics, Tec Labs - Centro de Inovação, Campus da FCUL, 1749-016, Lisboa, Lisboa, Portugal (Profissional)
Faculdade de Medicina, Universidade de Lisboa (FMUL), Av. Professor Egas Moniz, Edifício Egas Moniz, 1649-028, Lisboa, Lisboa, Portugal (Profissional)

Websites

www.dart-diagnostics.com (Profissional)
https://scholar.google.pt/citations?user=VCMp9iEAAAAJ&hl=en&oi=ao (Académico)

Domínios de atuação

Ciências Naturais - Ciências Biológicas - Biofísica
Ciências Naturais - Ciências Biológicas - Bioquímica

Idiomas

Idioma	Conversação	Leitura	Escrita	Compreensão
Português (Idioma materno)
Inglês	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)	Utilizador proficiente (C2)
Espanhol; Castelhano	Utilizador elementar (A2)	Utilizador independente (B1)	Utilizador elementar (A2)	Utilizador independente (B1)
Francês	Utilizador elementar (A1)	Utilizador independente (B1)	Utilizador elementar (A1)	Utilizador elementar (A1)

Formação

	Grau	Classificação
2009/02/23 Concluído	Bioengineering - Biophysics (Doutoramento) Vrije Universiteit Brussel, Bélgica "Biophysical Studies of Amyloid Fiber Stability" (TESE/DISSERTAÇÃO)	"Greatest Distinction" (maximum grade)
2002 Concluído	Licenciatura em Microbiologia (Licenciatura) Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal "Transferrin receptor expression in activated T-cells (awarded "18 valores", out of 20 maximum)" (TESE/DISSERTAÇÃO)	16 valores (out of 20, highest ranked)

Percurso profissional

Ciência

	Categoria Profissional Instituição de acolhimento	Empregador
2019/03/01 - Atual	Investigador Auxiliar (carreira) (Investigação)	Instituto de Medicina Molecular, Portugal
	Instituto de Medicina Molecular, Portugal
2017/03/13 - Atual	Investigador Coordenador (carreira) (Investigação)	DART DIagnostics, Portugal
	DART DIagnostics, Portugal

Docência no Ensino Superior

	Categoria Profissional Instituição de acolhimento	Empregador
2019/11/01 - Atual	Professor Auxiliar Convidado (Docente Universitário)	Faculdade de Medicina, Universidade de Lisboa, Portugal
	Faculdade de Medicina, Universidade de Lisboa, Portugal

Outros

	Categoria Profissional Instituição de acolhimento	Empregador
2014/01/01 - 2018/12/31	Principal Investigator, Investigador FCT Program, Starting Grant Level, Project IF/00772/2013: A nanotechnology approach to Flavivirus-targeted drug development strategies.	Instituto de Medicina Molecular, Portugal

2011/06/15 - 2013/12/31	Portuguese Foundation for Science and Technology post-doctoral research fellow	Instituto de Medicina Molecular, Portugal

2010/06/05 - 2011/06/05	Marie Curie Return Experienced Researcher	Instituto de Medicina Molecular, Portugal

2009/06/05 - 2010/06/05	Marie Curie Outgoing Experienced Researcher	Universidade Federal do Rio de Janeiro Instituto de Bioquímica Médica, Brasil

2009/03/01 - 2009/05/31	Portuguese Foundation for Science and Technology post-doctoral research fellow	Instituto de Medicina Molecular, Portugal

2006/10/01 - 2009/02/23	Portuguese Foundation for Science and Technology Ph.D. student research fellow	Vrije Universiteit Brussel Faculteit Wetenschappen en Bio-ingenieurswetenschappen, Bélgica

2004/04/01 - 2006/09/30	Boerhinger Ingelheim Fonds (BIF) Ph.D. student research fellow	Vrije Universiteit Brussel Faculteit Wetenschappen en Bio-ingenieurswetenschappen, Bélgica

2003/11/01 - 2004/03/31	Graduate researcher	Vlaams Instituut voor Biotechnologie - Vrije Universiteit Brussel Campus, Bélgica

2003/07/01 - 2003/10/31	Summer research trainee	European Molecular Biology Laboratory, Alemanha

2002/10/01 - 2003/06/30	Graduate research trainee	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

2001/08/01 - 2002/07/31	Undergraduate researcher	Universidade do Porto Instituto de Biologia Molecular e Celular, Portugal

2000/07/01 - 2000/08/31	Summer intern	Instituto Português de Oncologia do Porto Francisco Gentil EPE, Portugal

Projetos

Bolsa

	Designação	Financiadores
2020 - 2021	2020 -2021: P2020, Agência Nacional para a Inovação (ANI), P2020 I&D Empresas - COVID-19 (¿488.640): Highly sensitive immunoassay for SARS-CoV2 detection using new amplification technology. HighSenseCoV2 Investigador responsável DART DIagnostics, Portugal International Iberian Nanotechnology Laboratory, Portugal Inova+, Portugal Universidade de Lisboa Faculdade de Medicina, Portugal Instituto de Medicina Molecular, Portugal
2012/03 - 2015/02	AMYLOIDETECTORS: Employing amyloid fibrils as biosensors of the interaction of peptides with phospholipids and/or protein domains. Provided by PTCRIS: 117013 117013	Fundação para a Ciência e a Tecnologia, I.P.
2011/03 - 2014/08	LIPIDENGUE: The role of hepatic lipid membranes and lipid droplets in Dengue virus encapsidation. A gateway to new therapies. 112929 Provided by PTCRIS: 112929	Fundação para a Ciência e a Tecnologia, I.P.
2013 - 2014	2013-2014: FCG & FMUL, Project 20130008/PEC/BG (¿3.000): Studying the interaction with biological membranes of pep14-23, a novel dengue virus capsid protein inhibitor. FCG & FMUL, Project 20130008/PEC/BG Investigador responsável	Concluído
2010/01 - 2013/06	Amyloidogenic proteins: role of lipid-protein interaction in amyloid-like fibril formation 99947 Provided by PTCRIS: 99947 Investigador responsável	Fundação para a Ciência e a Tecnologia, I.P.

Projeto

	Designação	Financiadores
2019/03/01 - 2025/02/28	2019-2025: Developing peptide-based drugs against Zika and Dengue virus capsid proteins CEECIND/01670/2017/CP1396/CT0005 10.54499/CEECIND/01670/2017/CP1396/CT0005 Investigador responsável Universidade de Lisboa Instituto de Medicina Molecular João Lobo Antunes, Portugal	Fundação para a Ciência e a Tecnologia Em curso

Outro

	Designação	Financiadores
2010 - 2025	The interplay between lipid droplets, RNA and the capsid protein of dengue virus. 2010 Calouste Gulbenkian Life Sciences Frontier Research Award Investigador responsável
2017 - 2021	2017-ongoing: Caixa Capital & CoHiTEC, Translating Science into Business Award (¿100.000): DART Diagnostics ¿ Early disease detection made possible. DART Investigador responsável DART DIagnostics, Portugal
2018 - 2019	2018-2019: European Union SME Phase 1 Instrument, H2020 Award (¿50.000): DART Diagnostics ¿ Saving Time, Money and Lives Through Rapid Plug & Play Salmonella Diagnostics. DART SME Phase 1 Instrument Investigador responsável DART DIagnostics, Portugal	Concluído
2015 - 2017	2015-2017: FCG & FMUL, Project 20150014 (¿2.500): Improving flavivirus inhibitor pep14-23 biological activity. FCG & FMUL, Project 20150014 Investigador responsável	Concluído

Produções

Publicações

Artigo em revista

Priscilla L. S. Boon; Ana S. Martins; Xin Ni Lim; Francisco J. Enguita; Nuno C. Santos; Peter J. Bond; Yue Wan; Ivo C. Martins; Roland G. Huber. "Dengue Virus Capsid Protein Facilitates Genome Compaction and Packaging". International Journal of Molecular Sciences (2023): https://doi.org/10.3390/ijms24098158.
10.3390/ijms24098158
Ivo C. Martins; Rafaela C. Ricardo; Nuno C. Santos. "Dengue, West Nile, and Zika Viruses: Potential Novel Antiviral Biologics Drugs Currently at Discovery and Preclinical Development Stages". Pharmaceutics (2022): https://doi.org/10.3390/pharmaceutics14112535.
10.3390/pharmaceutics14112535
Sónia Gonçalves; Ivo C. Martins; Nuno C. Santos. "Nanoparticle-peptide conjugates for bacterial detection and neutralization: Potential applications in diagnostics and therapy". WIREs Nanomedicine and Nanobiotechnology (2022): https://doi.org/10.1002/wnan.1819.
10.1002/wnan.1819
Louis De Falco; Nelly M. Silva; Nuno C. Santos; Roland G. Huber; Ivo C. Martins. "The Pseudo-Circular Genomes of Flaviviruses: Structures, Mechanisms, and Functions of Circularization". Cells (2021): https://doi.org/10.3390/cells10030642.
10.3390/cells10030642
Ferreira, S.; Raimundo, A.; Menezes, R.; Martins, I.. "Islet amyloid polypeptide & amyloid beta peptide roles in Alzheimer's disease: Two triggers, one disease". Neural Regeneration Research 16 6 (2021): 1127-1130. http://www.scopus.com/inward/record.url?eid=2-s2.0-85097405155&partnerID=MN8TOARS.
10.4103/1673-5374.300323
Nelly M. Silva; Nuno C. Santos; Ivo C. Martins. "Dengue and Zika Viruses: Epidemiological History, Potential Therapies, and Promising Vaccines". Tropical Medicine and Infectious Disease 5 4 (2020): 150-150. https://doi.org/10.3390/tropicalmed5040150.
10.3390/tropicalmed5040150
Martins, Ivo C.; Santos, Nuno C.. "Intrinsically disordered protein domains in flavivirus infection". Archives of Biochemistry and Biophysics 683 (2020): 108298. http://dx.doi.org/10.1016/j.abb.2020.108298.
10.1016/j.abb.2020.108298
Raimundo, Ana F.; Ferreira, Sofia; Martins, Ivo C.; Menezes, Regina. "Islet Amyloid Polypeptide: A Partner in Crime With Aß in the Pathology of Alzheimer's Disease". Frontiers in Molecular Neuroscience 13 (2020): http://dx.doi.org/10.3389/fnmol.2020.00035.
10.3389/fnmol.2020.00035
André F. Faustino; Glauce M. Barbosa; Micael Silva; Miguel A. R. B. Castanho; Andrea T. Da Poian; Eurico J. Cabrita; Nuno C. Santos; Fabio C. L. Almeida; Ivo C. Martins. "Fast NMR method to probe solvent accessibility and disordered regions in proteins". Scientific Reports 9 1 (2019): https://doi.org/10.1038/s41598-018-37599-z.
10.1038/s41598-018-37599-z
Faustino, A.F.; Martins, A.S.; Karguth, N.; Artilheiro, V.; Enguita, F.J.; Ricardo, J.C.; Santos, N.C.; Martins, I.C.. "Structural and functional properties of the capsid protein of dengue and related flavivirus". International Journal of Molecular Sciences 20 16 (2019): http://www.scopus.com/inward/record.url?eid=2-s2.0-85071281504&partnerID=MN8TOARS.
10.3390/ijms20163870
Martins, A.S.; Carvalho, F.A.; Faustino, A.F.; Martins, I.C.; Santos, N.C.. "West Nile Virus Capsid Protein Interacts With Biologically Relevant Host Lipid Systems". Frontiers in cellular and infection microbiology 9 (2019): 8-8. http://www.scopus.com/inward/record.url?eid=2-s2.0-85061960310&partnerID=MN8TOARS.
10.3389/fcimb.2019.00008
Guedes, A.F.; Carvalho, F.A.; Domingues, M.M.; Macrae, F.L.; McPherson, H.R.; Sabban, A.; Martins, I.C.; et al. "Impact of ¿'¿' fibrinogen interaction with red blood cells on fibrin clots". Nanomedicine 13 19 (2018): 2491-2505. http://www.scopus.com/inward/record.url?eid=2-s2.0-85055917620&partnerID=MN8TOARS.
10.2217/nnm-2018-0136
Martins, A.S.; Martins, I.C.; Santos, N.C.. "Methods for lipid droplet biophysical characterization in flaviviridae infections". Frontiers in Microbiology 9 AUG (2018): http://www.scopus.com/inward/record.url?eid=2-s2.0-85051847327&partnerID=MN8TOARS.
10.3389/fmicb.2018.01951
Vicente Miranda, Hugo; Szego, Éva M.; Oliveira, Luís M. A.; Breda, Carlo; Darendelioglu, Ekrem; de Oliveira, Rita M.; Ferreira, Diana G.; et al. "Glycation potentiates a-synuclein-associated neurodegeneration in synucleinopathies". Brain 140 5 (2017): 1399-1419. http://dx.doi.org/10.1093/brain/awx056.
10.1093/brain/awx056
Remédios, M.; Carvalho, F.A.; Enguita, F.J.; Cardoso, C.; Martins, I.C.; Santos, N.C.; Leitão, A.L.. "Effects of Penicillium chrysogenum var. halophenolicum on kraft lignin: color stabilization and cytotoxicity evaluation". 3 Biotech 6 1 (2016): http://www.scopus.com/inward/record.url?eid=2-s2.0-84992305859&partnerID=MN8TOARS.
10.1007/s13205-016-0414-x
Faustino, André F.; Martins, Ivo C.; Carvalho, Filomena A.; Castanho, Miguel A. R. B.; Maurer-Stroh, Sebastian; Santos, Nuno C.. "Understanding Dengue Virus Capsid Protein Interaction with Key Biological Targets". Scientific Reports 5 1 (2015): http://dx.doi.org/10.1038/srep10592.
10.1038/srep10592
Faustino, A.F.; Guerra, G.M.; Huber, R.G.; Hollmann, A.; Domingues, M.M.; Barbosa, G.M.; Enguita, F.J.; et al. "Understanding dengue virus capsid protein disordered N-terminus and pep14-23-based inhibition". ACS Chemical Biology 10 2 (2015): 517-526. http://www.scopus.com/inward/record.url?eid=2-s2.0-84923345392&partnerID=MN8TOARS.
10.1021/cb500640t
Hauser, Charlotte A. E.; Maurer-Stroh, Sebastian; Martins, Ivo C.. "Amyloid-based nanosensors and nanodevices". Chemical Society Reviews 43 15 (2014): 5326. http://dx.doi.org/10.1039/c4cs00082j.
10.1039/c4cs00082j
Faustino, A.F.; Carvalho, F.A.; Martins, I.C.; Castanho, M.A.R.B.; Mohana-Borges, R.; Almeida, F.C.L.; Da Poian, A.T.; Santos, N.C.. "Dengue virus capsid protein interacts specifically with very low-density lipoproteins". Nanomedicine: Nanotechnology, Biology, and Medicine 10 1 (2014): 247-255. http://www.scopus.com/inward/record.url?eid=2-s2.0-84891022612&partnerID=MN8TOARS.
10.1016/j.nano.2013.06.004
Carvalho, F.A.; Martins, I.C.; Santos, N.C.. "Atomic force microscopy and force spectroscopy on the assessment of protein folding and functionality". Archives of Biochemistry and Biophysics 531 1-2 (2013): 116-127. http://www.scopus.com/inward/record.url?eid=2-s2.0-84876517392&partnerID=MN8TOARS.
10.1016/j.abb.2012.11.007
Pimenta, J.; Sardinha, J.; Marques, C.C.; Domingos, A.; Baptista, M.C.; Barbas, J.P.; Martins, I.C.; et al. "Inhibition of ovine in vitro fertilization by anti-Prt antibody: Hypothetical model for Prt/ZP interaction". Reproductive Biology and Endocrinology 11 1 (2013): http://www.scopus.com/inward/record.url?eid=2-s2.0-84875307776&partnerID=MN8TOARS.
10.1186/1477-7827-11-25
Pimenta, J.; Viegas, A.; Sardinha, J.; Martins, I.C.; Cabrita, E.J.; Fontes, C.M.G.A.; Prates, J.A.; Pereira, R.M.L.N.. "NMR solution structure and SRP54M predicted interaction of the N-terminal sequence (1-30) of the ovine Doppel protein". Peptides 49 (2013): 32-40. http://www.scopus.com/inward/record.url?eid=2-s2.0-84884176200&partnerID=MN8TOARS.
10.1016/j.peptides.2013.08.013
Carvalho, F.A.; Carneiro, F.A.; Martins, I.C.; Assunção-Miranda, I.; Faustino, A.F.; Pereira, R.M.; Bozza, P.T.; et al. "Dengue virus capsid protein binding to hepatic lipid droplets (LD) is potassium ion dependent and is mediated by LD surface proteins". Journal of Virology 86 4 (2012): 2096-2108. http://www.scopus.com/inward/record.url?eid=2-s2.0-84857094659&partnerID=MN8TOARS.
10.1128/JVI.06796-11
Martins, I.C.; Gomes-Neto, F.; Faustino, A.F.; Carvalho, F.A.; Carneiro, F.A.; Bozza, P.T.; Mohana-Borges, R.; et al. "The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif". Biochemical Journal 444 3 (2012): 405-415. http://www.scopus.com/inward/record.url?eid=2-s2.0-84862165670&partnerID=MN8TOARS.
10.1042/BJ20112219
Maurer-Stroh, S.; Debulpaep, M.; Kuemmerer, N.; De La Paz, M.L.; Martins, I.C.; Reumers, J.; Morris, K.L.; et al. "Exploring the sequence determinants of amyloid structure using position-specific scoring matrices". Nature Methods 7 3 (2010): 237-242. http://www.scopus.com/inward/record.url?eid=2-s2.0-77649265357&partnerID=MN8TOARS.
10.1038/nmeth.1432
Kuperstein, I.; Broersen, K.; Benilova, I.; Rozenski, J.; Jonckheere, W.; Debulpaep, M.; Vandersteen, A.; et al. "Neurotoxicity of Alzheimer's disease Aß peptides is induced by small changes in the Aß42 to Aß40 ratio". EMBO Journal 29 19 (2010): 3408-3420. http://www.scopus.com/inward/record.url?eid=2-s2.0-77957785420&partnerID=MN8TOARS.
10.1038/emboj.2010.211
Maurer-Stroh, S.; Debulpaep, M.; Kuemmerer, N.; De La Paz, M.L.; Martins, I.C.; Reumers, J.; Morris, K.L.; et al. "Erratum: Exploring the sequence determinants of amyloid structure using position-specific scoring matrices (Nature Methods (2010) 7 (237-242))". Nature Methods 7 10 (2010): http://www.scopus.com/inward/record.url?eid=2-s2.0-77957670464&partnerID=MN8TOARS.
10.1038/nmeth1010-855a
Martins, I.C.; Kuperstein, I.; Wilkinson, H.; Maes, E.; Vanbrabant, M.; Jonckheere, W.; Van Gelder, P.; et al. "Lipids revert inert Aß amyloid fibrils to neurotoxic protofibrils that affect learning in mice". EMBO Journal 27 1 (2008): 224-233. http://www.scopus.com/inward/record.url?eid=2-s2.0-38049056730&partnerID=MN8TOARS.
10.1038/sj.emboj.7601953
Schymkowitz, J.W.H.; Rousseau, F.; Martins, I.C.; Ferkinghoff-Borg, J.; Stricher, F.; Serrano, L.. "Prediction of water and metal binding sites and their affinities by using the Fold-X force field". Proceedings of the National Academy of Sciences of the United States of America 102 29 (2005): 10147-10152. http://www.scopus.com/inward/record.url?eid=2-s2.0-22544450150&partnerID=MN8TOARS.
10.1073/pnas.0501980102

Tese / Dissertação

Nascimento, André Rodrigues. "Biological activity and functions of the capsid protein of Zika virus and related flaviviruses". Mestrado, 2018. http://hdl.handle.net/10451/33851.

Propriedade Intelectual

Patente

Martins, Ivo C.. 2021. "Biomaterials. UKIPO, Provisional Nr. 2002343.8 (date: 20/02/2020); INPI, Provisional Nr: 20201000007119 (date: 10/02/2020); EPO, Definitive Nr. PCT/EP2021/053235 (filling date: 10/02/2021)".
Martins, Ivo C.. 2012. "DENV-DERIVED PEPTIDES AND METHODS FOR THE INHIBITION OF THE FLAVIVIRUS REPLICATION".
Martins, Ivo C.. 2011. "pep14-23 inhibition. Int. Patent Off., Patent Nr WO/2012/159187 (priority date: 26/05/2011)".
Martins, Ivo C.. 2007. "Means and methods for the production of amyloid oligomers". Bélgica.
Martins, Ivo C.. 2006. "Amyloid disassembly method. Int. Patent Off., Patent Nr WO/2008/028939 (priority: 13/03/2008; 04/05/2007; 08/09/2006)".

Atividades

Apresentação oral de trabalho

	Título da apresentação	Nome do evento Anfitrião (Local do evento)
2010	PRESENTATIONS AT CONFERENCES (2010-2021) Besides invited teaching and lectures presentations, I have been invited to present at 7 major national (3) and international (4) meetings, namely for large audiences: BPS Annual Meeting, Philadelphia, USA). Moreover, I have been selected for 19 oral communications and have contributed with 36 poster communications.

Orientação

	Título / Tema Papel desempenhado	Curso (Tipo) Instituição / Organização
2010 - 2021	GRADUATE RESEARCHERS SUPERVISION ACTIVITIES (ongoing & concluded): Post-doc (2): Joana Ricardo (2021-ongoing); Inês Santarino (2017-2019). Ph.D. students (3): Nelly Silva (2019-ongoing); Ana Martins (2015-ongoing), André Faustino (2012-2016). M.Sc. Students (6): Rafaela Ricardo (2020-ONGOING); Ana Silvestre (2018-2019), Nina Karguth (2018-2019); Mafalda Longarito (2017-2018), André Nascimento (2016-2018), Ana Martins (2013-2014), André Faustino (2010-2011). Orientador	SEVERAL (Ph.D. & M.Sc.) Instituto de Medicina Molecular, Portugal DART DIagnostics, Portugal
2010 - 2021	MD STUDENTS & OTHER RESEARCHERS SUPERVISION ACTIVITIES (ongoing & concluded): MD students: Clara Simões (2018-2019), Mafalda Longarito (2013-2017), Vanessa Artilheiro (2013-2015), International MD students’ SCORE program advisor (2010-2012). Graduate researchers: Ana Silvestre (2018), Patricia Carvalho (2015-2016), Gabriela Guerra (2012-2015). Undergraduate trainees: Raquel Gouveia (2020-2021), Teresa Rebelo (2020), Pedro Matias (2018), Margarida Pinto (2017), Ciência Viva supervisor (2012-2013). Orientador	Instituto de Medicina Molecular, Portugal DART DIagnostics, Portugal

Organização de evento

	Nome do evento Tipo de evento (Tipo de participação)	Instituição / Organização
2012 - 2017	ORGANISATION OF SCIENTIFIC ACTIVITIES: 2017/09: Invited workshop moderator, Integrated Methodologies for Studying IDPs, COST Meeting, Jerusalem, Israel, September 14-15, 2017. 2014/09: Organiser & lecturer of BPS networking event Protein-Ligand Interactions, CAML & iMM-FMUL, Lisbon, PT. 2013/12:Co-chair of iMM/FMUL 2013 PhD students meeting, iMM-FMUL, Lisbon, PT. 2013/02:Organiser & lecturer of BPS (USA) networking event Nanomedicine nanocourse, CAML PhD program, iMM-FMUL, Lisbon, PT 2012/06: Coordinator, lecturer & organiser of PLI course, iMM (2012 - 2017)

Curso / Disciplina lecionado

	Disciplina	Curso (Tipo)	Instituição / Organização
2019 - 2021	TEACHING: 2019-ongoing: Invited professor of biochemistry, MD students theoretical-practical biochemistry classes, FMUL, Lisbon, PT.
2017 - 2018	TEACHING: 2018/10: Invited workshop lecturer with the topic “DART Diagnostics, the ongoing journey of a startup” at 2nd NMS Symposium, CEDOC, Nova Medical School, Lisbon, PT, October 18-19, 2018. 2018/04: Invited workshop lecturer of “Emerging Magnetic Resonance Techniques to Study Dynamic Molecular Machines”, COST Action, Arrábida Monastery, Setúbal, PT, April 14-16, 2018. 2018/01 (T/L): Invited lecturer on “From proteins to peptides, From Science to entrepreneurship”, in LisbonBioMed PhD program, iMM-FMUL, Lisbon, PT, January 30, 2018.
2015 - 2017	TEACHING: 2017/04:Invited lecturer on “Structural biology and drug design meet atomic force microscopy”, IST, Lisbon, PT, April 21, 2017. 2017/01: Invited lecturer with the topic “From Dengue to Zika through West-Nile virus: a tale of three proteins and a peptide”, in LisbonBioMed PhD program, iMM-FMUL, Lisbon, PT, January 30, 2017. 2015/03: Invited lecturer at ITQB PhD program funded by FCT MolBioS, Oeiras, Pt. 2015/01 (T/L): Invited lecturer, iMM PhD program funded by FCT LisbonBioMed. IMM/FMUL/CAML;, Lisbon, PT

Outro júri / avaliação

	Descrição da atividade	Instituição / Organização
2010 - 2021	PEER-REVIEWER ACTIVITIES 2019: Invited external evaluator for the French National Agency for Scientific Research (ANR). Since 2012: Invited reviewer for scientific journals: ACS Chem. Biol., Sci. Rep., RSC Adv., Antimicr. Agents & Chemotherapy, Chem. Comm., New J of Chem., Virol., Int. J. Mol. Sci. and ACS Nano.	Instituto de Medicina Molecular, Portugal
2011 - 2019	JURY OF M.Sc. THESIS: 12/2019: Ana S. Silvestre, Microbiology M.Sc., FCUL, Lisbon, PT. 09/2019: Nina Karguth, Mol. Genet. Biomed. M.Sc., FCT-UNL, Caparica, PT. 06/2018: Mafalda L. Vasconcelos, Integrated M.Sc. in Medicine, FMUL, Lisbon, PT. 05/2018: André Nascimento, Biochemistry M.Sc., FCUL, Lisbon, PT. 07/2015: Rafalea F. Cássio, Neurosciences M.Sc., FMUL, Lisbon, PT. 10/2014: Ana S. Martins, Molec. Genet. Biomed. M.Sc., FCT-UNL, Caparica, PT. 09/2011:: André F.C. Faustino, Biochemistry M.Sc., FCUL, Lisbon, PT.	Instituto de Medicina Molecular, Portugal DART DIagnostics, Portugal Universidade Nova de Lisboa Faculdade de Ciências e Tecnologia, Portugal Universidade de Lisboa Faculdade de Ciências, Portugal Faculdade de Medicina, Universidade de Lisboa, Portugal
2012 - 2015	INSTITUTIONAL RESPONSIBILITIES AS SELECTION JURY OF GRANTHOLDERS CONTRACTS: 2015: iMM BI/2-2015 grant funded via FCT project PTDC/SAU-ENB/117013/2010, Lisbon, PT. 2012: iMM BI/52-2012 grant funded via FCT project PTDC/SAU-ENB/117013/2010, Lisbon, PT. 2012: iMM BI/53/2012 grant funded via FCT project PTDC/QUI-BIQ/112929/2009, Lisbon, PT. 2012: iMM BI/16-2012 grant funded via FCT project PTDC/SAU-ENB/117013/2010, Lisbon, PT. 2012: iMM BI/68-2011 grant funded via FCT project PTDC/QUI-BIQ/112929/2009, Lisbon, PT.	Instituto de Medicina Molecular, Portugal

Distinções

Prémio

2019	FCT Program Fellow, Concurso Estimulo ao Emprego Científico (CEEC/IND/01670/2017). Fundação para a Ciência e a Tecnologia, Portugal
2017	2016 COHiTEC & Caixa Capital Empreender Award
2017	COST & MCAA Travel Award
2015	International Travel Award Protein Society, Estados Unidos
2015	Hans Neurath Outstanding Promise Award Protein Society, Estados Unidos
2012	Young Scientists 2012 Program Bursary
2011	International Travel Award Biophysical Society (BPS), Estados Unidos
2010	Life Sciences Frontier Research Prize Fundação Calouste Gulbenkian, Portugal
2001	Best academic performance award Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
2000	Best academic performance award Universidade Católica Portuguesa Escola Superior de Biotecnologia, Portugal
1998	EU Young Scientists Portuguese first prize

Outra distinção

2008	Congress travel fellowship
2007	Travel fellowship Fundação para a Ciência e a Tecnologia, Portugal
1997	Final of the IV Environment Olympics Quercus Associação Nacional de Conservação da Natureza, Portugal